Produção Nacional
Revisado por pares
Paula Maria Silveira Soares Moura, Izildinha Maestá, Lígia M. S. S. Rugolo, Luís Felipe Ramos Berbel Angulski, Antônio Prates Caldeira, José Carlos Peraçoli, Marilza Vieira Cunha Rudge,
According to the World Health Organization, there are over 6.3 million perinatal deaths (PND) a year worldwide. Identifying the factors associated with PND is very helpful in building strategies to improve the care provided to mothers and their babies.To investigate the maternal, gestational and neonatal factors associated with PND at two different levels of care.Case-control study including 299 PND cases and 1161 infants that survived the early neonatal period (controls) between 2001-2006 in two ...
Tópico(s): Neonatal Respiratory Health Research
2014 - BioMed Central | Reproductive Health
José A. M. Prates, António Mário R. Ribeiro, António A.Dias Correia,
The role of endogenous cysteine endopeptidases (EC 3.4.22; calpains and cathepsins B, L and H) in rabbit (Oryctolagus cuniculus L.) meat tenderisation and some related changes (formation of the 30 kDa fragment and myofibrillar structure weakening), during ageing (9 days at +4°C), was studied for different types of muscle (I, IIB and IID). The results strongly suggest that cysteine peptidases, possibly calpains, play a major role in rabbit meat tenderisation, myofibrillar structure weakening and formation ...
Tópico(s): Animal Nutrition and Physiology
2001 - Elsevier BV | Meat Science
José Restolho, António Prates, Maria Norberta de Pinho, Maria Diná Afonso,
Thin spent sulphite liquor (SSL) generated in pulp and paper mills is a biomass resource that is usually concentrated and burnt in steam boilers. The general aim of this work was to investigate the application of membrane processes to filter the SSL produced by Eucalyptus globulus sulphite pulping, namely for the separation of the lignosulphonates (LS) from the sugars, LS fractionation to produce valuable products, and sugars concentration. Laboratory experiments were conducted in total recirculation, ...
Tópico(s): Lignin and Wood Chemistry
2009 - Elsevier BV | Biomass and Bioenergy
Produção Nacional
Revisado por pares
Alex Rafacho, Letícia Prates Roma, Sebastião Roberto Taboga, Antônio C. Boschero, José Roberto Bosqueiro,
Augmented glucose-stimulated insulin secretion (GSIS) is an adaptive mechanism exhibited by pancreatic islets from insulin-resistant animal models. Gap junction proteins have been proposed to contribute to islet function. As such, we investigated the expression of connexin 36 (Cx36), connexin 43 (Cx43), and the glucose transporter Glut2 at mRNA and protein levels in pancreatic islets of dexamethasone (DEX)-induced insulin-resistant rats. Study rats received daily injections of DEX (1 mg/kg body mass, ...
Tópico(s): Adipose Tissue and Metabolism
2007 - NRC Research Press | Canadian Journal of Physiology and Pharmacology
Produção Nacional
Revisado por pares
Gizele Carmem Fagundes Ramos, Jair Almeida Carneiro, Ana Teresa Fernandes Barbosa, José Márcio Girardi de Mendonça, Antônio Prates Caldeira,
Objetivo Avaliar a prevalência e os fatores associados aos sintomas depressivos em idosos não institucionalizados. Métodos Estudo transversal, analítico, de base populacional, cujos dados foram coletados entre maio e julho de 2013, em visitas domiciliares. Foi aplicado um questionário com variáveis sociodemográficas, comorbidades, utilização de serviços de saúde, escala de fragilidade (Edmonton Frail Scale), teste Timed Get Up and Go e a Escala de Depressão Geriátrica (Geriatric Depression Scale – GDS- ...
Tópico(s): Health, Nursing, Elderly Care
2015 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Jornal Brasileiro de Psiquiatria
Produção Nacional
Revisado por pares
Letícia Prates Roma, Kleber L.A. Souza, Everardo M. Carneiro, Antônio C. Boschero, José Roberto Bosqueiro,
Chronic administration of glucocorticoids (GC) leads to characteristic features of type 2 diabetes in mammals.The main action of dexamethasone in target cells occurs through modulation of gene expression, although the exact mechanisms are still unknown.We therefore investigated the gene expression profile of pancreatic islets from rats treated with dexamethasone using a cDNA array screening analysis.The expression of selected genes and proteins involved in mitochondrial apoptosis was further analyzed ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2012 - AEPress | General Physiology and Biophysics
O.A. Rego, Susana P. Alves, L.M.S. Antunes, H.J.D. Rosa, Cristina M. Alfaia, José A. M. Prates, Ana R. J. Cabrita, António J. M. Fonseca, R.J.B. Bessa,
The effects of supplementation with rapeseed, sunflower, and linseed oils (0.5 kg/d; good sources of oleic, linoleic, and linolenic acids, respectively) on milk responses and milk fat fatty acid (FA) profile, with special emphasis on rumen-derived biohydrogenation intermediates (BI), were evaluated in a replicated 4 x 4 Latin square study using 16 grazing dairy cows. The dietary treatments were 1) control diet: 20-h access to grazing pasture supplemented with 5 kg/d of corn-based concentrate mixture ( ...
Tópico(s): Muscle metabolism and nutrition
2009 - Elsevier BV | Journal of Dairy Science
José A. M. Prates, F. Garcia e Costa, António Mário R. Ribeiro, António A.Dias Correia,
The contribution of major structural (myofibrillar fragmentation upon mechanical treatment) and ultra-structural (Z-line degradation, loss of electron density of M-line, transversal disruption of sarcomeres at N2-line level, longitudinal fissure of myofibrils, and loss of transversal alignments of Z- and M-lines) changes in myofibrils to rabbit (Oryctolagus cuniculus L.) meat tenderisation, during the ageing period (9 days at +4 °C), was studied for different types of muscle (type I, semimembranosus proprius; ...
Tópico(s): Calpain Protease Function and Regulation
2002 - Elsevier BV | Meat Science
Produção Nacional
Revisado por pares
Laíse Angélica Mendes Rodrigues, Andreá Maria Eleutério de Barros Lima Martins, Marise Fagundes Silveira, Raquel Conceição Ferreira, João Gabriel Silva Souza, José António Raimundo Mendes da Silva, Antônio Prates Caldeira,
The prevalence and factors associated with the use of dental services in a representative, probabilistic, complex sample with two-stage clusters of preschoolers aged 18 to 36 months was estimated. Structured questionnaires were answered by parents/guardians and the preschoolers were assessed by trained and qualified dental surgeons. In the analysis the corrections for the design effect were considered and the magnitudes of the associations based on logistic regression (OR/IC 95%) were estimated. ...
Tópico(s): Global Maternal and Child Health
2014 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
José António Raimundo Mendes da Silva, Antônio Prates Caldeira,
Objetivou-se verificar a adequação de equipes de saúde da família aos padrões de qualidade do Ministério da Saúde e sua correlação com ações de atenção à saúde, segundo os profissionais de saúde. Foi utilizado o instrumento de Avaliação para Melhoria da Qualidade da Estratégia Saúde da Família (AMQ) em entrevistas conjuntas com médicos, enfermeiros e cirurgiões-dentistas. Foram definidos escores para cada uma das subdimensões avaliadas, segundo o número de conformidades aos padrões definidos no AMQ. ...
Tópico(s): Healthcare Policy and Management
2010 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Produção Nacional
Revisado por pares
Lucinéia de Pinho, João Marcus Oliveira Andrade, Alanna Fernandes Paraíso, Aristides Batista Maia Filho, John David Feltenberger, André Luiz Sena Guimarães, Alfredo Maurício Batista de Paula, Antônio Prates Caldeira, Ana Cristina de Carvalho Botelho, Maria José Campagnole‐Santos, Sérgio Henrique Sousa Santos,
The aim of this study was to evaluate the expression of RAS components and SIRTs enzymes in the adipose tissue of mice fed diets with different macronutrient composition.The body weight, food intake, and energy intake (kcal) were evaluated. Blood parameters (insulin sensitivity, glucose tolerance, total cholesterol, HDL-C triglyceride, and glucose levels) were also assessed. Real-time PCR was performed in epididymal adipose tissue samples to analyze the expression of renin, angiotensinogen (AGT), angiotensin- ...
Tópico(s): Biochemical effects in animals
2013 - Wiley | Obesity
Produção Nacional
Revisado por pares
Antônio Gonçalves Maciel, Francisco José Lopes de Sousa Diniz, Antônio Prates Caldeira,
Este estudo verifica o potencial da Estrategia Saude da Familia em reduzir a morbidade hospitalar por condicoes sensiveis a atencao primaria em Minas Gerais. Utilizou-se a analise longitudinal retrospectiva em serie historica de dez anos. A tecnica aplicou o modelo de regressao e, a partir do estimador encontrado, observou-se o percentual de cobertura capaz de impactar a reducao das taxas de morbidade hospitalar. Foi demonstrada a reducao de 68,87 pontos nas taxas de internacoes sensiveis ao cuidado ...
Tópico(s): Rural Development and Agriculture
2014 - Centro Brasileiro de Estudos de Saúde | Saúde em Debate
Produção Nacional
Revisado por pares
Mirna Rossi Barbosa-Medeiros, José F. Camargo, Luiza Augusta Rossi Barbosa, Antônio Prates Caldeira,
RESUMO O curso de Medicina possui elevada carga horária e habitualmente demanda grande envolvimento dos estudantes. Em consequência, acadêmicos de Medicina podem apresentar alta prevalência de estresse, Síndrome de Burnout e sintomas depressivos, que podem comprometer a qualidade de sua vida. Tais aspectos demonstram a necessidade de estudos mais profundos deste grupo populacional, especialmente em um novo contexto de acesso ao ensino superior. O presente estudo teve por objetivo avaliar globalmente ...
Tópico(s): Stress and Burnout Research
2018 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Jorge Pimenta, João Sardinha, C.C. Marques, Ana Domingos, M.C. Baptista, J.P. Barbas, Ivo C. Martins, Patrícia Mesquita, Pedro Pessa, Rui S. Soares, Aldino Viegas, Eurico J. Cabrita, EM António Horta, C.M.G.A. Fontes, AM José Prates, R.M. Pereira,
The impact of prion proteins in the rules that dictate biological reproduction is still poorly understood. Likewise, the role of prnt gene, encoding the prion-like protein testis specific (Prt), in ram reproductive physiology remains largely unknown. In this study, we assessed the effect of Prt in ovine fertilization by using an anti-Prt antibody (APPA) in fertilization medium incubated with spermatozoa and oocytes. Moreover, a computational model was constructed to infer how the results obtained ...
Tópico(s): Reproductive System and Pregnancy
2013 - BioMed Central | Reproductive Biology and Endocrinology
Produção Nacional
Revisado por pares
Silvio Antônio Garbelotti, Célio Fernando de Sousa‐Rodrigues, Emerson Alexandre Sgrott, José Carlos Prates,
Tópico(s): Shoulder and Clavicle Injuries
2001 - Springer Science+Business Media | Surgical and Radiologic Anatomy
Produção Nacional
Revisado por pares
Alessandra Aparecida Zinato Rodrigues, José Humberto de Queiróz, L. R. D. Faroni, Lucas Henrique Figueiredo Prates, Antônio Augusto Neves, André Fernando de Oliveira, Jéssika Faêda de Freitas, Fernanda Fernandes Heleno, Laércio Zambolim,
Food safety problems caused by pesticide residues in vegetables have become a top issue to raise public concern. In this study, bell peppers were grown in an experimental field and sprayed with two systemic (azoxystrobin and difenoconazole) and one contact (chlorothalonil) fungicides. Ozone (ozonated water and water continuously bubble with ozone) or conventional domestic (washing with distilled water, detergent, acetic acid, sodium bicarbonate, and sodium hypochlorite solutions) procedures were investigated ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2021 - Elsevier BV | Food Research International
Produção Nacional
José António Raimundo Mendes da Silva, Antônio Prates Caldeira,
A proposta Avaliação para Melhoria da Qualidade da Estratégia Saúde da Família (AMQ) foi desenvolvida para oferecer, aos gestores municipais, ferramentas de avaliação e gestão da qualidade da Estratégia Saúde da Família (ESF). No presente estudo, apresenta-se uma perspectiva de avaliação mediante a AMQ, focada na percepção dos profissionais de saúde. Foram realizadas entrevistas com os profissionais de nível superior das três categorias mais envolvidas com a ESF, utilizando-se os instrumentos da AMQ ...
Tópico(s): Global Maternal and Child Health
2011 - Fundação Oswaldo Cruz, Escola Politécnica de Saúde Joaquim Venâncio | Trabalho Educação e Saúde
Produção Nacional
Revisado por pares
Jair Almeida Carneiro, Gizele Carmem Fagundes Ramos, Ana Teresa Fernandes Barbosa, José Márcio Girardi de Mendonça, Fernanda Marques da Costa, Antônio Prates Caldeira,
RESUMO Objetivo: verificar a prevalência e os fatores associados à fragilidade em idosos não institucionalizados residentes ao norte de Minas Gerais, Brasil. Método: a coleta de dados ocorreu no domicílio em 2013, a partir de uma amostragem censitária por conglomerado. Foram analisadas variáveis demográficas e socioeconômicas, morbidades, utilização de serviços de saúde e o escore da Escala de Fragilidade de Edmonton. As razões de prevalências ajustadas foram obtidas por análise múltipla de regressão ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2016 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Produção Nacional
Revisado por pares
Carla Gabrielli, E Olave, António Sarmento, Cristina Ioshie Mizusaki, José Carlos Prates,
Tópico(s): Vascular Procedures and Complications
1997 - Springer Science+Business Media | Surgical and Radiologic Anatomy
Produção Nacional
Revisado por pares
Letícia Prates Roma, José Roberto Bosqueiro, Daniel A. Cunha, Everardo M. Carneiro, Ewa Gurgul-Convey, Sigurd Lenzen, Antônio C. Boschero, Kleber L.A. Souza,
Pancreatic β cells are very sensitive to reactive oxygen species (ROS) and this might play an important role in β cell death in diabetes. Dexamethasone is a synthetic diabetogenic glucocorticoid, which impairs pancreatic β cell function. Therefore we investigated the toxicity of dexamethasone in RINm5F insulin-producing cells and its dependence on the expression level of the antioxidant enzyme catalase, which inactivates hydrogen peroxide. This was correlated with oxidative stress and cell death. ...
Tópico(s): Diabetes and associated disorders
2009 - Elsevier BV | Free Radical Biology and Medicine
Produção Nacional
Revisado por pares
Cristiane Wanderley Cardoso, Monaise Madalena Oliveira e Silva, Antônio Carlos Bandeira, Renan Bispo Silva, Ana Paula Pitanga Barbuda Prates, Ênio Silva Soares, José Jorge Moreno Silva, Lázaro José Rodrigues de Souza, Mirela Maisa da Silva Souza, Marcela Almeida Muhana, Rosildete Silva Santos Pires, José Fernando Araujo Neto, Manuela Sampaio Souza Santos, Luiz Laureno Mafra, Thiago Alves, Mathias Alberto Schramm, Guilherme S. Ribeiro,
From late 2016 to early 2021, cases of Haff disease, a rare cause of rhabdomyolysis, possibly due to poisoning by palytoxin-like compounds in seafood, were detected in Salvador, Brazil. Surveillance was established to detect additional cases aiming at describing the clinical characteristics of the cases, identifying associated factors, estimating disease attack rate, and investigating the presence of biotoxins and trace metals in selected fish specimens obtained from cases.Between December/2016- ...
Tópico(s): Venomous Animal Envenomation and Studies
2021 - Elsevier BV | The Lancet Regional Health - Americas
Produção Nacional
Revisado por pares
Maria das Graças Mota Mourão, Antônio Prates Caldeira, José Vasconcelos-Raposo,
Este artigo tem por objetivo aprofundar a discussão acerca da avaliação no ensino superior no contexto atual das escolas médicas brasileiras, com vistas a estimular a reflexão e a discussão de todos aqueles que de uma forma ou de outra estejam envolvidos no processo educativo. Entendemos que pesquisas a respeito da temática nos permitem repensar práticas e construir propostas mais participativas, voltadas aos processos, considerando a própria experiência, as diversidades e a complexidade da instituição. ...
Tópico(s): Education and Public Policy
2009 - Associção Brasileira de Educação Médica | Revista Brasileira de Educação Médica
Produção Nacional
Revisado por pares
Maria José Reis, Stefanie Alvarenga Santos, Luciana L. Prates, Edênio Detmann, Gleidson Giordano Pinto de Carvalho, Antônio Carneiro Santana dos Santos, Luana Marta de Almeida Rufino, Lays Débora Silva Mariz, Felipe da Silva Neri, Eduardo Costa,
The main focus of this work was to verify the hypothesis that there are differences between cattle and sheep to obtain internal markers in tropical forages using in situ ruminal incubation. A presupposition that the indigestible fraction is exclusively inherent to feed was considered, and its ruminal incubation in different animal species should not change the estimate of this fraction; but should change the minimum time required to obtain this value, or the critical-time (Tc). The Tc to obtain indigestible ...
Tópico(s): Agriculture and Farm Safety
2017 - Elsevier BV | Animal Feed Science and Technology
Antonio Piras, Gianfranca Carta, Elisabetta Murru, Paula A. Lopes, Susana V. Martins, José A. M. Prates, Sebastiano Banni,
We have recently shown that PPAR alpha agonists induce N-oleoylethanolamide (OEA) and N-palmitoylethanolamide (PEA) biosynthesis. Conjugated linoleic acid (CLA), a known dietary PPAR alpha inducer, may therefore increase OEA and PEA levels and favor docosahexaenoic acid (DHA) biosynthesis by enhancing peroxisomal β-oxidation via induction of liver PPARα. To evaluate whether CLA is able to increase DHA, OEA and PEA levels and thereby influencing liver lipid deposition in a model of visceral obesity-induced ...
Tópico(s): Lipid metabolism and biosynthesis
2015 - Elsevier BV | Prostaglandins Leukotrienes and Essential Fatty Acids
Cristina M. Alfaia, Paulo J.L.C. Ribeiro, Maria João Trigo, António J. Alfaia, Matilde Castro, C.M.G.A. Fontes, R.J.B. Bessa, José A. M. Prates,
The effect of gamma radiation processing on the lipid content, fatty acid composition and conjugated linoleic acid (CLA) profile in frozen lamb meat was investigated. Samples of longissimus thoracis muscle from lambs fed lucerne basal diets either unsupplemented or supplemented with polyunsaturated vegetable oils were irradiated (7kGy) and analysed. CLA contents in lamb meat did not affect (P>0.05) the levels of lipid oxidation induced by the irradiation. No significant differences (P>0.05) were observed ...
Tópico(s): Animal Nutrition and Physiology
2007 - Elsevier BV | Meat Science
Produção Nacional
Sérgio Ricardo Marques, Ana María Itezerote, Romina Moreira, Marco Antonio De Angelis, José Carlos Prates,
RESUMEN: Debido a la importancia que tienen las variaciones musculares para cirujanos, como tambien para los profesionales del area de las imagenes, describimos dos variaciones de origen de la arteria occipital. Disecamos la region del cuello en 110 cadaveres de individuos, adultos, brasileros de ambos sexos, determinandose el origen, trayecto y diametro de la arteria occipital. La arteria occipital que se origina generalmente de la pared posterior de la arteria carotida externa, a nivel de la arteria ...
Tópico(s): Cerebral Venous Sinus Thrombosis
2002 - SciELO | Revista chilena de anatomía
Jorge Pimenta, Ana Domingos, P. Santos, C.C. Marques, Cátia Cantante, Ana Paula Santos, J.P. Barbas, M.C. Baptista, António Eduardo Horta, Aldino Viegas, Patrícia Mesquita, João Gonçalves, C.M.G.A. Fontes, José A. M. Prates, R.M. Pereira,
A hallmark of prion diseases or transmissible spongiform encephalopaties is the conversion of the cellular prion protein (PrPC), expressed by the prion gene (prnp), into an abnormally folded isoform (PrPSc) with amyloid-like features that causes scrapie in sheep among other diseases. prnp together with prnd (which encodes a prion-like protein designated as Doppel), and prnt (that encodes the prion protein testis specific - Prt) with sprn (shadow of prion protein gene, that encodes Shadoo or Sho) genes, ...
Tópico(s): Reproductive System and Pregnancy
2012 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Ana Márjory Paiva Sousa, Hévila Oliveira Salles, Hermógenes David de Oliveira, Beatriz Blenda Pinheiro de Souza, José de Lima Cardozo Filho, Daniel Nogoceke Sifuentes, Maura V. Prates, Carlos Bloch, Marcelo P. Bemquerer, Antônio Sílvio do Egito,
Cationic peptides found in Moringa oleifera seeds belong to different protein families and are described as the main flocculating agents of the species. In this study we report the identification and isolation of four new flocculant peptides, called Mo-HLPs 1–4, belonging to the family of hevein-like peptides, previously only known for their members' antimicrobial activity. Purification of the peptides followed two sequential membrane ultrafiltration steps and separation by reverse-phase liquid ...
Tópico(s): Coagulation and Flocculation Studies
2020 - Elsevier BV | Journal of Proteomics
Produção Nacional
Revisado por pares
M. M. Gontijo Neto, José Antônio Obeid, Odilon Gomes Pereira, Paulo Roberto Cecon, Augusto César de Queiroz, Cláudio Prates Zago, Magno José Duarte Cândido, Lídia Ferreira Miranda,
Foram avaliadas características agronômicas, fibra em detergente neutro (FDN), fibra em detergente ácido (FDA) e carboidratos solúveis e estruturais de cinco híbridos de sorgo forrageiro (AG-2002, AG-2005E, AGX-202, AGX-213 e AGX-215), cultivados sob quatro níveis de adubação NPK. Utilizou-se o delineamento em blocos casualizados, em esquema fatorial 5 x 4, com quatro repetições. As médias dos fatores qualitativos foram comparadas pelo teste de Tukey a 5 e 1% de probabilidade. Os híbridos avaliados ...
Tópico(s): Soil Management and Crop Yield
2004 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Célia Costa, Isabel Rosmaninho, Arminda Guilherme, José Alberto Ferreira, Joana Antunes, Ana Ortins‐Pina, Sara Prates, João Gaspar Marques, Filomena Azevedo, Ana Paula Cunha Chaves, Celeste Brito, António Fernandes Massa, João Sousa, Glória Velho, Inês Raposo, Gabriela Marques Pinto, V. Teixeira de Sousa, Ana Rodrigues Martins,
Introduction: There is a paucity of information regarding chronic urticaria patients’ care in a real-world setting. The objective of this study was to report and evaluate the baseline characteristics of Portuguese chronic urticaria patients refractory to H1-antihistamines included in the AWARE study. Material and Methods: This is a non-interventional cohort study. Adult patients with a diagnosis of chronic urticaria with symptoms for at least two months, refractory to H1-antihistamines, consulting ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2019 - Ordem dos Médicos | Acta Médica Portuguesa