Produção Nacional
Revisado por pares
Roque Aras, José Alberto Martins da Matta, Gildo Mota, Irênio Gomes, Aílton Melo,
OBJECTIVE: To determine the frequency of encephalic infarction and its contribution to lethality in patients with Chagas' disease and heart failure. METHODS: Medical records and autopsy reports of patients with Chagas' disease complicated by heart failure, who died at the Professor Edgar Santos Hospital of the Federal University of Bahia in the past 45 years were retrospectively analyzed. Data comprised information regarding the clinical history on hospital admission, complementary and anatomicopathological ...
Tópico(s): Adenosine and Purinergic Signaling
2003 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Aras Kadioglu, José Echenique, Sonia Manco, Marie‐Claude Trombe, Peter W. Andrew,
ABSTRACT In Streptococcus pneumoniae , the two-component signaling system MicAB was previously shown to contribute to repression of competence when oxygen is limited. In virulent strains expressing the serotype 2 and 6 capsule, mutation of the MicB kinase reduced the lag period of growth when cultures were switched from an aerobic to anaerobic atmosphere. After intranasal challenge of mice, the micB :: km mutation decreased virulence, as shown by the absence of symptoms and by a lower level of recovery ...
Tópico(s): Antibiotic Resistance in Bacteria
2003 - American Society for Microbiology | Infection and Immunity
Produção Nacional
Revisado por pares
Cristiano Silva Pinho, Alex Cleber Improta‐Caria, Roque Aras, Francisco José Gondim Pitanga,
SUMMARY INTRODUCTION The COVID-19 pandemic, caused by infections from a novel human coronavirus, has been reported since December 2019 in China but was only made official in March 2020. Since then, it has had an impact worldwide, both due to its aggressiveness and its fast propagation. Society has been facing this pandemic by following the recommendations and determinations of the WHO and the strategies deployed by governmental institutions. Among these, social isolation has been shown to be the ...
Tópico(s): Physical Education and Training Studies
2020 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Dashti Ali, Aras Asaad, María-José Jiménez, Vidit Nanda, Eduardo Paluzo-Hidalgo, M. Soriano-Trigueros,
Attempts to incorporate topological information in supervised learning tasks have resulted in the creation of several techniques for vectorizing persistent homology barcodes. In this paper, we study thirteen such methods. Besides describing an organizational framework for these methods, we comprehensively benchmark them against three well-known classification tasks. Surprisingly, we discover that the best-performing method is a simple vectorization, which consists only of a few elementary summary ...
Tópico(s): Image Retrieval and Classification Techniques
2023 - IEEE Computer Society | IEEE Transactions on Pattern Analysis and Machine Intelligence
Federica Pederiva, Rosa Aras‐López, José Ignacio Rodrı́guez, L Martínez, Juan A. Tovar,
Abstract Introduction Pulmonary morbidity in survivors of congenital diaphragmatic hernia (CDH) is caused by hypoplasia, barotraumas, or other reasons. We have previously shown deficient tracheal innervation in rats with CDH. Now we examine whether bronchopulmonary innervation is also abnormal in both infants and rats with CDH. Material and Methods Sections of E15, E18, and E21 rat lungs were immunostained for Protein gene product 9.5 and S100 antibodies. Similar immunostaining was performed on tissue from ...
Tópico(s): Neuroscience of respiration and sleep
2010 - Elsevier BV | Journal of Pediatric Surgery
Produção Nacional
Revisado por pares
Júlio César Vieira Braga, Francisco José Farias Borges dos Reis, Roque Aras, Nei Dantas Costa, Claudilson José de Carvalho Bastos, Renata Silva, Alana Cristiny Miranda Soares, Ademir Moura Júnior, Silvana Ásfora, Adriana Lopes Latado,
OBJETIVO: Descrever as características clínicas e terapêuticas de pacientes com insuficiência cardíaca (IC) secundária a miocardiopatia chagásica crônica, bem como avaliar se estas são diferentes nas demais etiologias. MÉTODOS: Foram analisados prospectivamente pacientes atendidos no período de agosto de 2003 a junho de 2004, em um ambulatório de referência para IC. RESULTADOS: Foram incluídos 356 pacientes com o diagnóstico de IC. Miocardiopatia chagásica foi a etiologia mais freqüente, (48% dos ...
Tópico(s): Cardiomyopathy and Myosin Studies
2006 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Claudilson J. C. Bastos, Roque Aras, Gildo Mota, Francisco José Farias Borges dos Reis, Juarez Pereira Dias, Robson Silva de Jesus, Miralba Silva Freire, Eline Gomes de Araújo, Juliana Prazeres, Maria Fernanda Rios Grassi,
Background Outbreaks of orally transmitted Trypanosoma cruzi continue to be reported in Brazil and are associated with a high mortality rate, mainly due to myocarditis. Methods This study is a detailed report on the disease progression of acute Chagas disease in 13 patients who were infected during two micro-outbreaks in two northeastern Brazilian towns. Clinical outcomes as well as EKG and ECHO results are described, both before and after benznidazole treatment. Results Fever and dyspnea were the ...
Tópico(s): Viral Infections and Immunology Research
2010 - Public Library of Science | PLoS neglected tropical diseases
Ani Ozcelik, Raquel Pereira, Alexander von Weber, M. Paszkiewicz, Marco Carlotti, Tobias Paintner, L. Zhang, Tao Lin, Yi‐Qi Zhang, Johannes V. Barth, T. van den Nobelen, Ryan C. Chiechi, Matthias Jakob, Ueli Heiz, S. Chiussi, Aras Kartouzian, Florian Klappenberger, José Lorenzo Alonso‐Gómez,
Chiroptical methods have been proven to be superior compared to their achiral counterparts for the structural elucidation of many compounds. To expand the use of chiroptical systems to everyday applications, the development of functional materials exhibiting intense chiroptical responses is essential. Particularly, tailored and robust interfaces compatible with standard device operation conditions are required. Herein, we present the design and synthesis of chiral allenes and their use for the functionalization ...
Tópico(s): Surface Chemistry and Catalysis
2018 - American Chemical Society | Langmuir
José Echenique, Aras Kadioglu, Susana Romão, Peter W. Andrew, Marie‐Claude Trombe,
ABSTRACT In the Streptococcus pneumoniae genome, stkP , encoding a membrane-associated serine/threonine kinase, is not redundant (L. Novakova, S. Romao, J. Echenique, P. Branny, and M.-C. Trombe, unpublished results). The data presented here demonstrate that StkP belongs to the signaling network involved in competence triggering in vitro and lung infection and bloodstream invasion in vivo. In competence, functional StkP is required for activation of comCDE upstream of the autoregulated ring orchestrated ...
Tópico(s): Bacterial Infections and Vaccines
2004 - American Society for Microbiology | Infection and Immunity
António Gil‐Nagel, Mercé Falip, Rocío Sánchez‐Carpintero, María Reyes Abad, José Luís Poveda, José Ángel Aibar, Elena Cardenal‐Muñoz, Luís Miguel Aras, Rosa Sánchez, Arantxa Sancho-López, José Luís Trillo, María Torrejón, Alicia Gil,
Dravet Syndrome (DS) is a severe, developmental epileptic encephalopathy (DEE) that begins in infancy and is characterized by pharmaco-resistant epilepsy and neurodevelopmental delay. Despite available antiseizure medications (ASMs), there is a need for new therapeutic options with greater efficacy in reducing seizure frequency and with adequate safety and tolerability profiles. Fenfluramine is a new ASM for the treatment of seizures associated with DS as add-on therapy to other ASMs for patients aged ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
2022 - Elsevier BV | Epilepsy & Behavior
Produção Nacional
Revisado por pares
Wanessa Maria de Freitas Aras, Juliana S.M. Barroso, Alberto Blay, José Augusto Rodrigues, Alessandra Cassoni,
The aim of this study was to evaluate Y-TZP surface pretreatment with different protocols on microshear bond strength (μSBS) ceramic-cement interface. One hundred and sixty pre-sintered IPS e-max ZirCAD (Ivoclar-Vivadent) blocks were randomly divided into sixteen groups according to surface treatment (n=20): G1- no treatment (control); G2- ceramic primer; G3- tribochemical silica coating; G4- tribochemical silica coating+primer; G5- airborne particle abrasion (Al2O3); G6- airborne particle abrasion (Al2O3)+ ...
Tópico(s): Endodontics and Root Canal Treatments
2016 - Elsevier BV | Ceramics International
Zeynep Ciğeroğlu, Ömür Aras, Carlos A. Pinto, Mahmut Bayramoğlu, Ş. İsmail Kırbaşlar, José M. Lorenzo, Francisco J. Barba, Jorge A. Saraiva, Selin Şahin,
The extraction of phenolic compounds from grapefruit leaves assisted by ultrasound-assisted extraction (UAE) was optimized using response surface methodology (RSM) by means of D-optimal experimental design and artificial neural network (ANN). For this purpose, five numerical factors were selected: ethanol concentration (0-50%), extraction time (15-60 min), extraction temperature (25-50 °C), solid:liquid ratio (50-100 g L-1 ) and calorimetric energy density of ultrasound (0.25-0.50 kW L-1 ), whereas ultrasound ...
Tópico(s): Food Industry and Aquatic Biology
2018 - Wiley | Journal of the Science of Food and Agriculture
Ana Catarina Fragoso, Rosa Aras‐López, L Martínez, José Estevão‐Costa, Juan A. Tovar,
Tópico(s): Tracheal and airway disorders
2012 - Springer Science+Business Media | Pediatric Surgery International
Produção Nacional
Revisado por pares
Eugênia da Silva Lima, Cristiano Gonçalves da Cruz, Fabiane Costa Santos, Mansueto Gomes Neto, Hugo Souza Bittencourt, Francisco José Farias Borges dos Reis, Roque Aras, Armênio Costa Guimarães, Erenaldo de Souza Rodrigues-Junior,
FUNDAMENTO: A insuficiência cardíaca é um importante problema de saúde pública, apresentando a dispneia e a fadiga como principais sintomas clínicos. A utilização do suporte ventilatório não invasivo vem atuando como coadjuvante da reabilitação cardíaca na tentativa de melhorar a capacidade funcional dos pacientes. OBJETIVO: Avaliar a capacidade funcional de pacientes com insuficiência cardíaca submetidos ao suporte ventilatório. MÉTODOS: Foram avaliados dados sociodemográficos, qualidade de vida, ...
Tópico(s): Cardiovascular Function and Risk Factors
2011 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Eugênia da Silva Lima, Cristiano Gonçalves da Cruz, Fabiane Costa Santos, Mansueto Gomes Neto, Hugo Souza Bittencourt, Francisco José Farias Borges dos Reis, Roque Aras, Armênio Costa Guimarães, Erenaldo de Souza Rodrigues-Junior,
Heart failure (HF) is an important public health problem, of which main clinical symptoms are dyspnea and fatigue. Noninvasive ventilatory support has been used as adjuvant therapy in cardiac rehabilitation in order to improve the functional capacity of patients.To evaluate the functional capacity of patients with HF submitted to ventilatory support.We evaluated the sociodemographic information, as well as data on quality of life, blood pressure (BP), peripheral oxygen saturation (SpO2), dyspnea, lactate ...
Tópico(s): Cardiovascular and exercise physiology
2011 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
José Alberto Martins da Matta, Roque Aras, Cristiano Macedo, Cristiano Gonçalves da Cruz, Eduardo Martins Netto,
Background Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease. We studied stroke correlates in cardiomyopathy patients with focus on the chagasic etiology. Methodology/Principal Findings We performed a cross-sectional review of medical records of 790 patients with a cardiomyopathy. Patients with chagasic (329) and non-chagasic (461) cardiomyopathies were compared. There were 108 stroke cases, significantly more ...
Tópico(s): Advanced battery technologies research
2012 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Jamary Oliveira‐Filho, Ana C.P. Ornellas, Cathy R. Zhang, Luciana Mattos Barros Oliveira, Théo Araújo-Santos, Valéria M. Borges, Laís M. G. B. Ventura, Francisco José Farias Borges dos Reis, Roque Aras, André Maurício Souza Fernandes, Jonathan Rosand, Steven M. Greenberg, Karen L. Furie, Natalia S. Rost,
To investigate the effect of COX-2 polymorphism and its product, prostaglandin E2 (PGE2), on stroke risk in an endemic area for Chagas disease. In a separate cohort, to investigate the effect of COX-2 polymorphisms on the total burden of cerebral white matter disease.Cases were outpatients with ischemic stroke; controls were stroke-free subjects from 2 outpatient clinics (heart failure and caregivers of a movement disorders clinic). We extracted DNA from total blood to investigate the rs20417 COX- ...
Tópico(s): Insect symbiosis and bacterial influences
2015 - Elsevier BV | Journal of Stroke and Cerebrovascular Diseases
Produção Nacional
Revisado por pares
Roque Aras, Claudilson Bastos, Gildo Mota, Fábio L. Sodré, Agnaluce Moreira, Armando Dias Tavares, José Carlos Lima,
Chagas disease is still a major tropical diseasein Latin America, affecting 16 to 18 million people.About 6 million people are infected with thecausative organism, Trypanosoma cruzi , in Brazil[1]. However, it often remains for decades in itsindeterminate form, symptomless, with tissue injuryin about 30% of the cases, which eventually willevolve to serious arrhythmia and sudden death [1].There is no effective clinical or laboratorytechnique to monitor chronic Chagas myocarditis.Several researchers ...
Tópico(s): Cardiomyopathy and Myosin Studies
2003 - Elsevier BV | The Brazilian Journal of Infectious Diseases
António Assunção, José d’ Encarnação, Amílcar Guerra,
EnglishOn etudie deux autels identifies, en 2008, dans le territoire de la civitas Igaeditanorum, quand on etait en train de faire la rehabilitation d�une ancienne eglise chretienne. Ils sont dedies a Asidia, divinite preromaine jusqu�a present inconnue, qui porte sur un des autels l�epithete de Poltucea, sans doute lie a la gentilitas Polturiciorum, qui fait une des dedicaces. A son tour, le nom de la gentilitas doit etre lie a l�anthroponyme Polturus, qui est lui aussi y mentionne. Ces circonstances ...
Tópico(s): Medieval Architecture and Archaeology
2010 - | Revista portuguesa de arqueologia
Clériston Jesus da Cruz, Denise Silva Bitencourt,
... trabalho, alguns trechos de Meu folclore (1957), de José Aras, pelo pseudônimo de Jota Sara, são observados à ... da Enciclopédia Católica Popular e outras obras de José Aras (1963, 2003, 2009). Ademais, Fiorin (2006), Barros (2005), ...
Tópico(s): Cultural, Media, and Literary Studies
2016 - Universidade de São Paulo, Letras e Ciências Humanas | Estudos Semióticos
Produção Nacional
André Rodrigues Durães, Yasmin de Souza Lima Bitar, Igor Schonhofen, Kethyren Santos Oliveira Travassos, Larissa Vitória Pereira, José Admirço Lima Filho, Mansueto Gomes Neto, Roque Aras, Leonardo Roever,
Tópico(s): Cardiac Valve Diseases and Treatments
2020 - Adis, Springer Healthcare | American Journal of Cardiovascular Drugs
Angel Moya, Richard Sutton, Fabrizio Ammirati, Jean‐Jacques Blanc, Michele Brignole, Johannes B. Dahm, Jean‐Claude Deharo, Jacek Gajek, Knut Gjesdal, Andrew D. Krahn, M Massin, Mauro Pepi, Thomas Pezawas, R. Ruiz Granell, François Sarasin, Andrea Ungar, J. Gert van Dijk, Edmond Walma, Wouter Wieling, M. O. Evseev,
... 3 (USA), Henning Mølgard (Denmark), Rain Paju (Эстония), Aras Puodziukynas (Литва), Antonio Raviele (Италия), Pilar Roman5 (Испания), Martin Scherer (Германия), Ronald Schondorf 9 (Канада), Rosa Sicari (Италия), Peter Vanbrabant 4 (Бельгия), Christian Wolpert1 (Германия), Jose Luis Zamorano (Испания).
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2010 - Stolichnaya Izdatelskaya Kompaniya | Rational Pharmacotherapy in Cardiology
Produção Nacional
Revisado por pares
Júlio César Vieira Braga, Francisco José Farias Borges dos Reis, Roque Aras, Nei Dantas, Almir Galvão Vieira Bitencourt, Flavia S. Neves, Adriana Lopes Latado,
Some studies showed increased mortality in chagasic patients but most of these studies did not perform statistical adjustments to socioeconomic variables. The main objective of this study was to investigate if there is an independent association between Chagas etiology and mortality in patients with heart failure and moderate to severe left ventricle systolic dysfunction. Stratified analysis by the variables associated to chagasic etiology and multivariate analysis through logistic regression were ...
Tópico(s): Cardiomyopathy and Myosin Studies
2007 - Elsevier BV | International Journal of Cardiology
Tolga Aksu, Kıvanç Yalın, Leah A. John, José Osorio, Jeffrey R. Winterfield, Dursun Aras, Rakesh Gopinathannair,
We aimed to determine the effects of conscious and deep sedation on vagal response (VR) characteristics during ganglionated plexus (GP) ablation.Forty consecutive patients undergoing GP ablation for vasovagal syncope were divided to receive conscious sedation with midazolam (Group 1, n = 29) or deep sedation with the midazolam-propofol combination (Group 2, n = 11). VR was defined on three levels. R-R interval increase of >50% (Level 1); R-R interval increase of 20%-50% (Level 2); and R-R interval increase ...
Tópico(s): Pain Management and Treatment
2021 - Wiley | Journal of Cardiovascular Electrophysiology
Ángel Aledo‐Serrano, Ana Mingorance, Vicente Villanueva, Juan José García‐Peñas, António Gil‐Nagel, Susana Boronat, JoséÁngel Aibar, Silvia Cámara, María José Yániz, Luís Miguel Aras, Bárbara Blanco, Rocío Sánchez‐Carpintero,
The appropriate management of patients with Dravet Syndrome (DS) is challenging, given the severity of symptoms and the burden of the disease for patients and caregivers. This study aimed to identify, through a qualitative methodology and a Delphi consensus-driven process, a set of recommendations for the management of DS to guide clinicians in the assessment of the clinical condition and quality of life (QoL) of DS patients, with a special focus on patient- and caregiver-reported outcomes (PROs).This ...
Tópico(s): Infant Development and Preterm Care
2022 - Frontiers Media | Frontiers in Neurology
Jörn Lepelmeier, José Lorenzo Alonso‐Gómez, Farinaz Mortaheb, Ulrich Boesl, Ueli Heiz, Aras Kartouzian,
Experimental observation of chiroptical inversion within the same electronic transition due to single vibronic excitations in a supersonic beam.
Tópico(s): Spectroscopy and Quantum Chemical Studies
2017 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Andrés Moyá, Richard Sutton, Fabrizio Ammirati, Jean-Jacques Blanc, Michele Brignole, Johannes B. Dahm, Jean‐Claude Deharo, Jacek Gajek, Knut Gjesdal, Andrew D. Krahn, M Massin, Mauro Pepi, Thomas Pezawas, R. Ruiz Granell, François Sarasin, Andrea Ungar, J. Gert van Dijk, Edmond Walma, Wouter Wieling, Haruhiko Abe, David G. Benditt, Wyatt W. Decker, Blair P. Grubb, Horacio Kaufmann, Carlos A. Morillo, Brian Olshansky, Steve W. Parry, Robert S. Sheldon, Win K. Shen, Alec Vahanian, A. Auricchio, Jeroen J. Bax, Claudio Ceconi, Verónica Dean, Gerasimos Filippatos, Christian Funck‐Brentano, Richard Hobbs, Patricia M. Kearney, Theresa A. McDonagh, Keith McGregor, Bogdan A. Popescu, Željko Reiner, Udo Sechtem, Per Anton Sirnes, Michał Tendera, Panos Vardas, Petr Widimský, A. Auricchio, Esmeray Acartürk, Felicita Andreotti, Riccardo Asteggiano, Urs Bauersfeld, Abdelouahab Bellou, Athanase Bénétos, Johan Brandt, Mina K. Chung, Pietro Cortelli, Antoine Da Costa, Fabrice Extramiana, José M. Ferro, Bülent Görenek, Antti Hedman, Rafael Hirsch, Gabriela Kaliská, Rose Anne Kenny, Keld Per Kjeldse, Rachel Lampert, Henning Mølgard, Rain Paju, Aras Puodžiūkynas, Antonio Raviele, Pilar Román, Martin Scherer, Ronald Schondorf, Rosa Sicari, Peter Vanbrabant, Christian Wolpert, José Luis Zamorano,
Las Guías de Práctica Clínica recogen la opinión de la ESC y se han elaborado tras una consideración minuciosa de las evidencias disponibles en el momento en que fueron escritas. Se anima a los profesionales de la sanidad a que las tengan en plena consideración cuando ejerzan su juicio clínico. No obstante, las Guías de Práctica Clínica no deben invalidar la responsabilidad individual de los profesionales de la salud a la hora de tomar decisiones adecuadas a las circunstancias individuales de cada ...
Tópico(s): Medical research and treatments
2009 - Elsevier BV | Revista Española de Cardiología
Sara Lonardi, Iwona Ługowska, Christopher Jackson, Anne O’Donnell, Rastilav Bahleda, Marcelo Garrido, Loes M Latten-Jansen, Matías Chacón, Habte A. Yimer, Trixia Camacho, Srivani Konduri, Urvi Aras, Kinjal Sanghavi, Heather Vezina, Sonia Dolfi, Federica Alessi, R. Donald Harvey, José Trigo, Aitana Calvo,
2575 Background: Immunotherapy has transformed cancer survival expectations. Nivolumab (NIVO), a programmed death-1 inhibitor, is approved for intravenous (IV) administration across multiple cancers. BMS is developing a subcutaneous (SC) NIVO formulation with a permeation enhancer, recombinant human hyaluronidase PH20 enzyme (rHuPH20), to allow for more rapid delivery and the potential to decrease treatment burden. We report the first data on pharmacokinetics (PK), pharmacodynamics, safety, and immunogenicity ...
Tópico(s): Lung Cancer Research Studies
2021 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... BAYTAŞOĞLU Evaluatıon of The Water Qualıty of Kura-Aras Rıver Basıns, Transboundary Rıvers of Türkiye, Accordıng to Some Bıotıc Indıces, Journal of Anatolian Environmental and Animal Sciences 8, no.33 (Sep 2023): 474–483.https://doi.org/10.35229/jaes.1331904Ignacio Masson, Andrea Bertora, Juan José Rosso, José González Castelain, Sabrina Dubny, Natalia Othax, ...
Tópico(s): Invertebrate Taxonomy and Ecology
1993 - University of Chicago Press | Journal of the North American Benthological Society
Tópico(s): Electric and Hybrid Vehicle Technologies
2023 - | Revista aragonesa de administración pública/Revista aragonesa de administración pública