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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Cynthia Siqueira Silva, Humberto Pena Couto, Rony Antônio Ferreira, José Brandão Fonseca, Augusto Vidal da Costa Gomes, Rita da Trindade Ribeiro Nobre Soares,

Este trabalho foi realizado com o objetivo de determinar os valores nutricionais de milhos de quatro qualidades, obtidos por meio de estratificação em mesa densimétrica, para frangos de corte em diferentes idades. Os milhos foram designados como: MDA - milho de densidade alta; MDI - milho de densidade intermediária; MDB - milho de densidade baixa; e MDT - milho de densidade total, composto de 30% de MDA, 60% de MDI e 10% de MDB. Dois ensaios biológicos foram conduzidos utilizando-se o método tradicional ...

Tópico(s): Livestock and Poultry Management

2008 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia

Artigo Brasil Produção Nacional Revisado por pares

Domingos Sávio Campos Paciullo, Priscila Beligoli Fernandes, Carlos Augusto Brandão de Carvalho, Mirton José Frota Morenz, Marina Aparecida Lima, Rogério Martins Maurício, Carlos Augusto de Miranda Gomide,

The objective of this study was to evaluate the pasture traits and performance of crossbreed dairy heifers in a silvopastoral system (SPS) and open pasture (OP) of Urochloa decumbens, after 14-years of management. In the SPS, an average reduction of 46% in the photosynthetically active radiation (PAR) was calculated in relation to the OP. Experimental design was a randomized complete block, with three replications and two treatments (SPS and OP), evaluated in two seasons (summer and autumn), during three ...

Tópico(s): Rangeland Management and Livestock Ecology

2021 - Elsevier BV | Livestock Science

Artigo Brasil Produção Nacional Revisado por pares

Ana Nunes Paiva, Josivan Gomes Lima, Anna Cecília Queiroz de Medeiros, Heverton A O Figueiredo, Raiana L de Andrade, Marcela Abbott Galvão Ururahy, Adriana Augusto de Rezende, José Brandão‐Neto, Maria das Graças Almeida,

Chromium is an essential mineral that contributes to normal glucose function and lipid metabolism. This study evaluated the effect of chromium picolinate (CrPic) supplementation in patients with type 2 diabetes mellitus (T2DM). A four month controlled, single blind, randomized trial was performed with 71 patients with poorly controlled (hemoglobin A1c [HbA1c] > 7%) T2DM divided into 2 groups: Control (n = 39, using placebo), and supplemented (n = 32, using 600 μg/day CrPic). All patients received nutritional ...

Tópico(s): Metabolism, Diabetes, and Cancer

2015 - Elsevier BV | Journal of Trace Elements in Medicine and Biology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Naira Josele Neves de Brito, Jorge A. López, Maria Aparecida do Nascimento, José Benilson Martins Macedo, Gabriel Araújo da Silva, Cláudia Nunes Oliveira, Adriana Augusto de Rezende, José Brandão‐Neto, Aline Schwarz, Maria das Graças Almeida,

The present study aimed to determine whether the leaves of Turnera ulmifolia Linn. var. elegans extract exert significant antioxidant activity. The antioxidant activity of its hydroethanolic extract (HEETU) was evaluated by assessing (a) its radical scavenging ability in vitro, and (b) its in vivo effect on lipid peroxidation and antioxidant enzyme activities. The in vitro antioxidant assay (DPPH) clearly supported HEETU free radical scavenging potential. Moreover, glutathione content and antioxidant ...

Tópico(s): Antioxidant Activity and Oxidative Stress

2012 - Elsevier BV | Food and Chemical Toxicology

Artigo Acesso aberto

Eva Brandão, Augusto Ferreria, José L. Loureiro,

The anterior biopercular syndrome is characterized by facio-pharyngo-glosso-masticatory diplegia, with automatic dissociation of movements. It generally translates bilateral opercular lesion, often of vascular etiology. There are very few cases described with unilateral lesions. We present the case of a patient with a bilateral anterior opercular syndrome caused by unilateral infarction. A síndrome biopercular anterior caracteriza-se por diplegia facio-faringo-glosso-mastigatória, com dissociação ...

Tópico(s): Reconstructive Surgery and Microvascular Techniques

2013 - Ordem dos Médicos | Acta Médica Portuguesa

Artigo Brasil Produção Nacional

Lauro Seda, Ródio Brandão Câmara, Arthur Cukiert, José Augusto Burattini, Pedro Paulo Mariani,

Different techniques have already been described for reconstructing the sellar floor after transsphenoidal (TS) procedures. This paper reports on the use of fibrin glue alone without grafting or the use of implants in the reconstruction of the sellar floor after TS. Five hundred sixty-seven patients who submitted to TS for pituitary and sellar region tumors were studied. No intraoperative cerebrospinal fluid (CSF) leak occurred in 503 patients (group 1); in the remaining 64 patients (group 2), intraoperative ...

Tópico(s): Meningioma and schwannoma management

2006 - Elsevier BV | Surgical Neurology

Artigo Brasil Produção Nacional Revisado por pares

Anelise Cristina Osorio César Dória, Fernanda Ramos Figueira, Jhonatan S. Brandão de Lima, José Augusto Nunes Figueira, Alonso Hernan Ricci Castro, Bogos Nubar Sismanoglu, Gilberto Petraconi Filho, Homero Santiago Maciel, Sônia Khouri, Rodrigo Sávio Pessoa,

Candida spp are present in 70%–90% of invasive infections and non-thermal plasmas operated at atmospheric pressure have been gaining attention as a new antimicrobial strategy for medical devices. This work presents studies on the inactivation efficacy of biofilms of Candida albicans grown in polyurethane (PU), main constituent of central venous catheter, by atmospheric gliding arc plasma jet operated at different process parameters: gas chemistry/flow (argon, helium, or its mixture with air) and plasma ...

Tópico(s): Plasma Diagnostics and Applications

2018 - IOP Publishing | Plasma Research Express

Artigo Brasil Produção Nacional Revisado por pares

Rand Randall Martins, Ulisvaldo Brunno de Oliveira Macedo, Lúcia Dantas Leite, Adriana Augusto de Rezende, José Brandão‐Neto, Maria das Graças Almeida,

The generation of reactive oxygen species resulting from physical activity may trigger adaptive processes at the reproductive level and in the antioxidant defense system itself. The objective of this study was to investigate the effects of moderate daily swimming and lipoic acid (LA) supplementation on estrous cycle duration and pro-oxident and antioxidant markers in young Wistar rats. Animals were submitted to daily swimming (for 1 h) for 30 days, between 1300 h and 1400 h. The following study groups ...

Tópico(s): Muscle metabolism and nutrition

2011 - NRC Research Press | Applied Physiology Nutrition and Metabolism

Artigo Brasil Produção Nacional Revisado por pares

Tiago Felipe Senes-Lopes, Jorge A. López, Viviane Souza do Amaral, José Brandão‐Neto, Adriana Augusto de Rezende, Jefferson Romáryo Duarte da Luz, Zaira da Rosa Guterres, Maria das Graças Almeida,

Medicinal plants have been used in primary healthcare since the earliest days of humankind. Turnera subulata and Spondias mombin × Spondias tuberosa are widely used in the Brazilian Northeast to treat several diseases. The aim of this study was to evaluate the genotoxic effects of the leaf extracts of these species by the somatic mutation and recombination test in the somatic cells of Drosophila melanogaster wings. The experiments were performed using standard and high-bioactivation cross and three ...

Tópico(s): Essential Oils and Antimicrobial Activity

2018 - Mary Ann Liebert, Inc. | Journal of Medicinal Food

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Jefferson Romáryo Duarte da Luz, Thayse Evellyn Silva do Nascimento, Gabriel Araújo da Silva, Adriana Augusto de Rezende, José Brandão‐Neto, Marcela Abbott Galvão Ururahy, André Ducati Luchessi, Jorge A. López, Hugo Alexandre Oliveira Rocha, Maria das Graças Almeida,

The present study evaluated the in vitro and in vivo potential toxicological effects, and the in vitro anticoagulant action of Licania rigida Benth crude leaf extract (CELR) and ethyl acetate fraction (AFLR). The in vitro toxicity was assessed by means of the MTT assay using mouse fibroblasts (3T3) and human embryonic kidney cells (HEK-293), while the acute oral toxicity test employed Wistar rats. No apparent toxicity was observed after exposure to the extracts. Regarding the anticoagulant capacity, ...

Tópico(s): Bee Products Chemical Analysis

2021 - Elsevier BV | South African Journal of Botany

Artigo Brasil Produção Nacional Revisado por pares

Igor Paiva Ramos, Heleno Brandão, Augusto S. Zanatta, Érica de Oliveira Penha Zica, Reinaldo José da Silva, Daercy M.M. de Rezende-Ayroza, Edmir Daniel Carvalho,

Historically, the ichthyofauna of large Brazilian rivers has been subject to anthropogenic interference, such as impoundments. Currently, cage fish farming systems are a new source of impact on aquatic ecosystems. The objective of this study was to characterise the impact of freshwater fish farms on the feeding of five species of Neotropical freshwater fish. Specimens of Astyanax altiparanae, Galeocharax knerii, Iheringicthys labrosus, Pimelodus maculatus and Plagioscion squamosissimus were sampled ...

Tópico(s): Fish Biology and Ecology Studies

2013 - Elsevier BV | Aquaculture

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Martha Lima Brandão, Márcia Chame, José Luís Passos Cordeiro, Sérgio Augusto de Miranda Chaves,

Estudos sobre biodiversidade permitem avaliações ecossistêmicas e monitoramentos de impactos e mudanças ambientais

Tópico(s): Helminth infection and control

2009 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology

Artigo Acesso aberto Revisado por pares

José Barros, Augusto Ferreira Umpiérrez, Ana Filipa Brandão, Carolina Lemos, Fernando Dias Correia, Joana Damásio, Assunção Tuna, Jorge Sequeiros, Paula Coutinho, Isabel Alonso, José Pereira‐Monteiro,

SCN1A is the most relevant gene in epilepsy. Only seven SCN1A mutations have been identified in 10 familial hemiplegic migraine (FHM) kindreds worldwide.In 2009, we presented a kindred with FHM due to the L263V SCN1A mutation. In the current study, we report a novel FHM3 kindred from the same village. The first family exhibited the co-occurrence of FHM and epilepsy. No case of epilepsy was observed in the new kindred. An L263V mutation was found in all patients, and the haplotype analysis supports ...

Tópico(s): Neurological disorders and treatments

2014 - SAGE Publishing | Cephalalgia

Artigo Brasil Produção Nacional Revisado por pares

Jefferson Romáryo Duarte da Luz, Thayse Evellyn Silva do Nascimento, Leandro Vinícius Fernandes de Morais, Ana Katarina Menezes da Cruz, Adriana Augusto de Rezende, José Brandão Neto, Marcela Abbott Galvão Ururahy, André Ducati Luchessi, Jorge A. López, Hugo Alexandre Oliveira Rocha, Maria das Graças Almeida,

Cardiovascular and thromboembolic disturbances are the main causes of disease-related deaths worldwide. Regardless of the etiological factors involved in thrombus formation, coagulation is mainly activated by thrombin, one of the most important blood clotting molecules. Thus, this study evaluated the Turnera subulata leaf crude extract, its ethyl acetate fraction effect on the coagulation cascade, and its possible side effects. Their phytocomposition indicated polyphenols, mainly flavonol-3-O-glycosylate ...

Tópico(s): Blood Pressure and Hypertension Studies

2019 - Mary Ann Liebert, Inc. | Journal of Medicinal Food

Artigo Brasil Produção Nacional Revisado por pares

Elaine C Ferreira, Raul Hernandes Bortolin, Francisco Paulo Freire‐Neto, Karla Simone Costa de Souza, João Felipe Bezerra, Marcela Abbott Galvão Ururahy, Ana Maria de Oliveira Ramos, Silvia Tchernin Himelfarb, Bento João Abreu, Thiago Vinícius Nadaleto Didone, Lúcia Fátima Campos Pedrosa, Aldo Cunha Medeiros, Sonia Q. Doi, José Brandão‐Neto, Rosário Dominguez Crespo Hirata, Luciana Augusto de Rezende, Maria das Graças Almeida, Mário Hiroyuki Hirata, Adriana Augusto de Rezende,

Type 1 diabetes mellitus (T1DM) and estrogen deficiency are associated with several alterations in bone turnover. Zinc (Zn) is required for growth, development, and overall health. Zinc has been used in complementary therapy against bone loss in several diseases. We hypothesized that Zn supplementation represents a potential therapy against severe bone loss induced by the combined effect of estrogen deficiency and T1DM. We evaluated the protective effect of Zn against bone alterations in a chronic ...

Tópico(s): Trace Elements in Health

2017 - Elsevier BV | Nutrition Research

Artigo Brasil Produção Nacional Revisado por pares

José Brandão‐Neto, Carlos A.B. Silva, Adriana Augusto de Rezende, Maria das Graças Almeida, Valéria Sf Sales, Júlio Sérgio Marchini,

Zinc is an essential micronutrient that is directly involved in the physiology of insulin, and zinc metabolism could play a role in the pathogenesis of diabetes mellitus and its complications. On the other hand, low zinc absorption and hyperzincuria in diabetic animals and humans have indicated that diabetics are more susceptible to zinc deficiency. This study was designed to compare zinc metabolism in ten insulin-dependent diabetic patients with ten healthy controls, using an oral zinc tolerance ...

Tópico(s): Pharmacological Effects and Toxicity Studies

2003 - Elsevier BV | Nutrition Research

Artigo Brasil Produção Nacional Revisado por pares

Ulisvaldo Brunno de Oliveira Macedo, Rand Randall Martins, Francisco Paulo Freire Neto, Yonara Monique da Costa Oliveira, Aldo da Cunha Medeiros, José Brandão‐Neto, Adriana Augusto de Rezende, Maria das Graças Almeida,

Oxidative stress is associated with postmenopause and is also responsible for various metabolic alterations. The redox imbalance observed during ovarian decline can be induced experimentally by bilateral ovariectomy in rats. In addition to hormone replacement, regular moderate physical exercise is indicated to prevent several common postmenopausal diseases. This study aimed to assess the effect of daily swimming on the antioxidant defense system of oophorectomized Wistar rats. Control and oophorectomized ...

Tópico(s): Paraoxonase enzyme and polymorphisms

2013 - NRC Research Press | Applied Physiology Nutrition and Metabolism

Artigo Acesso aberto Brasil Produção Nacional

José Francalino Vital, Germán Augusto Murrieta Morey, Natália Brandão PEREIRA, José Celso de Oliveira Malta,

O presente estudo investiga a presença de diplostomídeos parasitas em dois peixes curimatídeos, Potamorhina latior e Potamorhina pristigaster, além de listar todos os peixes reportados como hospedeiros para Austrodiplostomum compactum na Amazônia brasileira. Os peixes foram coletados em oito lagos de várzea do rio Solimões, no período de fevereiro de 2013 a dezembro de 2015. Foram analisados cem indivíduos de P. latior e sessenta e nove indivíduos de P. pristigaster, nos quais foram encontrados ...

Tópico(s): Fish Biology and Ecology Studies

2017 - | Folia Amazónica

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Domingos Sávio Campos Paciullo, Carlos Augusto Brandão de Carvalho, Luiz Januário Magalhães Aroeira, Mirton José Frota Morenz, Fernando César Ferraz Lopes, Roberto Oscar Pereyra Rossiello,

O objetivo deste trabalho foi avaliar características morfofisiológicas e o valor nutritivo da Brachiaria decumbens, nas épocas chuvosas de 2003 e 2004, em um sistema silvipastoril, com faixas de 30 m de largura com essa gramínea, alternadas com faixas de 10 m com árvores de Acacia mangium, A. angustissima, Mimosa artemisiana, Leucaena leucocephala x L. diversifolia, Eucalyptus grandis. Foi adotado o delineamento de blocos ao acaso, em parcelas subsubdivididas (características morfofisiológicas) ...

Tópico(s): Soil Management and Crop Yield

2007 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira

Artigo Brasil Produção Nacional Revisado por pares

Thiago Nogueira Lucon, Adivane Terezinha Costa, Paulo Galvão, Mariângela Garcia Praça Leite, Thiago José Augusto Madeira, Leonardo Brandão Nogueira,

The main public water supply in the São Miguel watershed (MG, Brazil) comes from a well-developed karst region, where information about hydraulic communications between caves entrances, sinkholes, recharge and discharge areas are still unknown. The study aims to identify regional hydrogeological processes describing groundwater hydrochemical evolution, interactions between meteoric, surface and ground waters, recharge and discharge sources, and possible hydraulic communications for proper management ...

Tópico(s): Groundwater and Watershed Analysis

2020 - Elsevier BV | Journal of South American Earth Sciences

Artigo Brasil Produção Nacional Revisado por pares

Érika Dantas de Medeiros Rocha, Lúcia Dantas Leite, Maria de Fátima Paiva Baracho, Maria Goretti do Nascimento Santos, Dina Maria de Araújo, Mardone Cavalcante França, Carlos Antônio Bruno da Silva, Maria das Graças Almeida, Adriana Augusto de Rezende, Júlio Sérgio Marchini, José Brandão‐Neto,

<i>Background/Aims:</i> Berardinelli-Seip syndrome (BSS), also termed congenital generalized lipodystrophy or congenital generalized lipoatropic diabetes, is a rare autosomal recessive disease characterized by the nearly complete absence of metabolically active adipose tissue from birth, extreme insulin resistance, diabetes mellitus, and hepatomegaly. The aim of this study was to evaluate the effect of diet intervention and oral zinc supplementation on the metabolic control of BSS patients. < ...

Tópico(s): RNA Research and Splicing

2010 - Karger Publishers | Annals of Nutrition and Metabolism

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Júlia Brandão Gontijo, Fabiana S. Paula, Andressa Monteiro Venturini, Caio Augusto Yoshiura, Clóvis Daniel Borges, José Mauro Sousa de Moura, Brendan J. M. Bohannan, Klaus Nüsslein, Jorge L. M. Rodrigues, Siu Mui Tsai,

The Amazonian floodplain forests are dynamic ecosystems of great importance for the regional hydrological and biogeochemical cycles and function as a significant CH4 source contributing to the global carbon balance. Unique geochemical factors may drive the microbial community composition and, consequently, affect CH4 emissions across floodplain areas. Here, we report the in situ composition of CH4 cycling microbial communities in Amazonian floodplain sediments. We considered how abiotic factors ...

Tópico(s): Microbial Community Ecology and Physiology

2021 - Wiley | Molecular Ecology

Artigo Brasil Produção Nacional Revisado por pares

Arthur Cukiert, José Augusto Burattini, Pedro Paulo Mariani, Ródio Brandão Câmara, Lauro Seda, Cristine Mella Baldauf, Meire Argentoni, Carla Baise‐Zung, Cássio Roberto Forster, Valeria Antakli Mello,

Summary: Purpose: We report on the efficacy and safety of extended one‐stage callosal section performed in a large and homogeneous series of patients. Methods: Seventy‐six patients with Lennox–Gastaut (n = 28) and Lennox‐like (n = 48) syndrome were studied (42 male patients; mean age, 11.2 years). All patients had multiple seizure types per day, including atonic, tonic–clonic, atypical absence, myoclonic, and tonic seizures. All of them were developmentally impaired. The EEG showed intense secondary bilateral ...

Tópico(s): Neonatal and fetal brain pathology

2006 - Wiley | Epilepsia

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Verônica Schmitz, Rhana Berto da Silva Prata, Mayara Garcia de Mattos Barbosa, Mayara Abud Mendes, Sheila Santos Brandão, Thaís Porto Amadeu, Luciana Silva Rodrigues, Helen Ferreira, Fabrício da Mota Ramalho Costa, Jéssica Brandão dos Santos, Fabiana dos Santos Pacheco, Alice de Miranda Machado, José Augusto da Costa Nery, Mariana A. Hacker, Anna Maria Sales, Roberta Olmo Pinheiro, Euzenir Nunes Sarno,

Erythema Nodosum Leprosum (ENL) is an immune reaction in leprosy that aggravates the patient´s clinical condition. ENL presents systemic symptoms of an acute infectious syndrome with high leukocytosis and intense malaise clinically similar to sepsis. The treatment of ENL patients requires immunosuppression and thus needs to be early and efficient to prevent both disabilities and permanent nerve damage. Some patients experience multiple episodes of ENL and prolonged use of immunosuppressive drugs ...

Tópico(s): Blood disorders and treatments

2016 - Public Library of Science | PLoS neglected tropical diseases

Artigo Revisado por pares

Ângela Carneiro, Rufino Silva, Maria J. Veludo, Augusto Barbosa, José M. Ruiz‐Moreno, Manuel Falcão, Elisete Brandão, Fernando Falcão‐Reis,

<i>Aim:</i> Evaluation of safety and efficacy of intravitreal ranibizumab in the treatment of choroidal neovascularization (CNV) secondary to causes other than age-related macular degeneration (AMD) or pathological myopia (PM). <i>Methods:</i> Retrospective and multicentric analysis of 21 eyes with CNV. Nine eyes had angioid streaks, 5 inflammatory chorioretinal diseases, 3 central serous chorioretinopathy and 4 idiopathic CNV. Follow-ups lasted ≧3 months. Best-corrected visual acuity ( ...

Tópico(s): Glaucoma and retinal disorders

2010 - Karger Publishers | Ophthalmologica

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Lucas F. de Lima, Pedro F. Brandão, Tiago Augusto Donegatti, Rui Miguel Ramos, Luís Moreira Gonçalves, Arnaldo Alves Cardoso, Elisabete Alves Pereira, José A. Rodrigues,

Aldehydes are relevant analytes in a wide range of samples, in particular, food and beverages but also body fluids. Hydrazines can undergo nucleophilic addition with aldehydes or ketones giving origin to hydrazones (a group of stable imines) that can be suitably used in the identification of aldehydes. Herein, 4-hydrazinobenzoic acid (HBA) was, for the first time, used as the derivatizing agent in analytical methodologies using liquid chromatography aiming the determination of low-molecular aldehydes. ...

Tópico(s): Analytical chemistry methods development

2018 - Elsevier BV | Talanta

Capítulo de livro Brasil Produção Nacional Revisado por pares

Guilherme Valle Loures Brandão, Wilian Daniel Henriques do Amaral, Caio Augusto Rabite de Almeida, José Alberto Barroso Castañon,

Every year many technologies are developed and implemented in such a way that fundamentally alters how we create, develop and interact with the environment. Virtual Reality has been broadly spread on architecture by allowing users to immerse on a digital universe or in an unbuilt project simulation. On engineering and architecture, project solutions and proposal visualization are essential for the diverse steps understanding and new project solutions development. Such tools help on speeding up processes, ...

Tópico(s): Architecture, Art, Education

2018 - Springer Science+Business Media | Lecture notes in computer science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Juliano Lara Fernandes, Roney Orismar Sampaio, Carlos Manuel de Almeida Brandão, Tarso Augusto Duenhas Accorsi, Luiz Francisco Cardoso, Guilherme Sobreira Spina, Flávio Tarasoutchi, Pablo Maria Alberto Pomerantzeff, José Otávio Costa Auler Júnior, Max Grinberg,

Pulmonary hypertension represents an important cause of morbidity and mortality in patients with mitral stenosis who undergo cardiac surgery, especially in the postoperative period. The aim of this study was to test the hypothesis that inhaled nitric oxide (iNO) would improve the hemodynamic effects and short-term clinical outcomes of patients with mitral stenosis and severe pulmonary hypertension who undergo cardiac surgery in a randomized, controlled study. Twenty-nine patients (4 men, 25 women; ...

Tópico(s): Cardiac Arrest and Resuscitation

2011 - Elsevier BV | The American Journal of Cardiology

Artigo Revisado por pares

Ana M. G. Silva, Kléber T. de Oliveira, M. Amparo F. Faustino, Maria G. P. M. S. Neves, Augusto C. Tomé, Artur M. S. Silva, José A. S. Cavaleiro, Paula Brandão, Vı́tor Félix,

Abstract β‐Butadienyl‐ and β,β′‐dibutadienylporphyrins were prepared by the Wittig reaction of β‐formyl‐ and β,β′‐diformyl‐ meso ‐tetraphenylporphyrins with allylic phosphorus ylide. Subsequent treatment of β‐butadienylporphyrin with dienophiles afforded the corresponding Diels–Alder adducts. In the absence of dienophiles, β‐butadienylporphyrin underwent electrocyclization, followed by oxidation, to give monobenzoporphyrin in good yield. Similarly, adjacent and opposite dibenzoporphyrins were successfully ...

Tópico(s): Photodynamic Therapy Research Studies

2007 - Wiley | European Journal of Organic Chemistry