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COURTNEY OF PENWITH., February 2. F. J. C. HEARNSHAW., BRONZE STAR., F. H. ELY, President, EVALINE D. HUTCHINSON. Hon, W. BRAMWELL BOOTH., J. B. CAPPER., L. S. JAMESON. 4, Thurloe-place, S.W., Feb. 2., GEORGE E. BUCKLE. London, Feb. 2., Wallington, Feb. 3. E. BRABROOK., E. P. STILL, Secretary.,

... And Sugar., "The Cleansing Stain." A Play By José Echegaray., Grave Dutch Anxiety. Faced By Starvation., Greek View ...

1917 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Gülden Gökşen, Didem Demir, Kuldeep Dhama, Manoj Kumar, Ping Shao, Fengwei Xie, Noemí Echegaray, José M. Lorenzo,

Current trends are shifting away from using synthetic compounds in favor of discovering new natural component sources that will allow them to create goods that are healthful, environmentally friendly, sustainable, and profitable. The food industry, in light of these trends, has opted to look for safe natural ingredients that will allow the production of low-fat, artificial-additive-free, gluten-free, prebiotic, and fortified foods. Similarly, the pharmaceutical and medical industries have attempted ...

Tópico(s): Food composition and properties

2023 - Elsevier BV | International Journal of Biological Macromolecules

Artigo Acesso aberto

Sergio García-Benítez, Txomin Pérez-Bilbao, Martín Echegaray, José Luis Felipe,

ResumenEl objetivo del presente estudio fue analizar la estructura temporal y las acciones características del pádel de élite.Se analizaron 9 torneos del Padel Pro Tour ® 2012 con un total de 28 partidos y 59 sets (32 categoría masculina vs. 27 femenina).Los partidos fueron analizados mediante el software LongMatch V.0.20.1 ® , comparando ítems sobre aspectos temporales y acciones de juego entre hombres y mujeres.Los resultados ponen de manifiesto diferencias significativas en la mayoría de las variables ...

Tópico(s): Health and Lifestyle Studies

2016 - Universidad Católica San Antonio de Murcia | Cultura Ciencia y Deporte

Artigo Acesso aberto Revisado por pares

María del C. Rivera-Sánchez, Marilyn García-Arriaga, Gerard Hobley, Ana V. Morales-de-Echegaray, José M. Rivera,

Most drugs are small molecules because of their attractive pharmacokinetics, manageable development and manufacturing, and effective binding into the concave crevices of bio-macromolecules. Despite these features, they often fall short when it comes to effectively recognizing the surfaces of bio-macromolecules. One way to overcome the challenge of biomolecular surface recognition is to develop small molecules that become self-assembled ligands (SALs) prior to binding. Herein, we report SALs made ...

Tópico(s): Bacteriophages and microbial interactions

2017 - American Chemical Society | ACS Omega

Artigo Acesso aberto Revisado por pares

Derek J. Royer, Jose Echegaray-Mendez, Liwen Lin, Grzegorz B. Gmyrek, Rose Mathew, Daniel R. Saban, Victor L. Perez, Daniel J.J. Carr,

Whether complement dysregulation directly contributes to the pathogenesis of peripheral nervous system diseases, including sensory neuropathies, is unclear. We addressed this important question in a mouse model of ocular HSV-1 infection, where sensory nerve damage is a common clinical problem. Through genetic and pharmacologic targeting, we uncovered a central role for C3 in sensory nerve damage at the morphological and functional levels. Interestingly, CD4 T cells were central in facilitating this ...

Tópico(s): Complement system in diseases

2019 - eLife Sciences Publications Ltd | eLife

Artigo Revisado por pares

Susana Ravassa, Begoña López, Ramón Querejeta, Kattalin Echegaray, Gorka San José, María U. Moreno, Javier Beaumont, Arantxa González, Javier Dı́ez,

Objective: Myocardial fibrosis is associated with alterations in the cross-linking and deposition of collagen type I (CCL and CD, respectively). We aimed to evaluate whether the combination of circulating biomarkers of CCL [the carboxy-terminal telopeptide of collagen type I to matrix metalloproteinase-1 ratio (CITP : MMP-1)] and CD [the carboxy-terminal propeptide of procollagen type I (PICP)] identifies myocardial fibrosis phenotypes with distinct clinical outcome in hypertensive patients with heart ...

Tópico(s): Lipoproteins and Cardiovascular Health

2017 - Lippincott Williams & Wilkins | Journal of Hypertension

Artigo Revisado por pares

Santiago Ramirez, Ana Barahona,

... del Rio Hortega. Jose M. Lopez Pinero Jose Echegaray. Jose Manuel Sanchez RonSantiago Ramirez and Ana BarahonaSantiago Ramirez ...

Tópico(s): Archaeological and Historical Studies

1993 - University of Chicago Press | Isis

Artigo Revisado por pares

Naiara Aginako, Goretti Echegaray, José María Martínez‐Otzeta, Igor Rodríguez, Elena Lazkano, Basilio Sierra,

This paper presents a novel approach for iris dissimilarity computation based on Computer Vision and Machine Learning. First, iris images are processed using well-known image processing algorithms. Pixels of the output image are considered the input of the previously trained classifiers, obtaining the a posteriori probability for each of the considered class values. The main novelty of the presented work remains in the computation of the dissimilarity value of two iris images as the distance between ...

Tópico(s): User Authentication and Security Systems

2017 - Elsevier BV | Pattern Recognition Letters

Artigo Revisado por pares

Nimesh A. Patel, Kenneth C. Fan, Nicolas A. Yannuzzi, Jose J. Echegaray, Nish Patel, Sander R. Dubovy, David Sia, David Ehmann, Basil K. Williams, Ajay E. Kuriyan, Luis J. Haddock, André J. Witkin, Ninel Z. Gregori, Caroline R. Baumal, Jayanth Sridhar,

Abstract We report a case series of 12 eyes that underwent retinal detachment (RD) repair after secondary implantation of Akreos AO60 intraocular lens (IOL) with a subset experiencing the complication of IOL opacification. Major predisposing risk factors for retinal detachment included trauma (42%), prior vitrectomy (33%), and ectopia lentis (17%). Opacification developed in two eyes with gas tamponade and three with silicone oil tamponade. Two eyes required explantation of the IOL. Permanent visually ...

Tópico(s): Glaucoma and retinal disorders

2020 - Elsevier BV | Ophthalmology Retina

Revisão Revisado por pares

Michael Ramos, Jose J. Echegaray, Sonia Kuhn-Asif, Allan Wilkinson, Alex Yuan, Arun D. Singh, Andrew Browne,

Radiation retinopathy is a serious vision-impairing complication of radiation therapy used to treat ocular tumors. Characterized by retinal vasculopathy and subsequent retinal damage, the first sign of radiation retinopathy is the preferential loss of vascular endothelial cells. Ensuing ischemia leads to retinal degradation and late stage neovascularization. Despite the established disease progression, the pathophysiology and cellular mechanisms contributing to radiation retinopathy remain unclear. ...

Tópico(s): Glaucoma and retinal disorders

2019 - Elsevier BV | Experimental Eye Research

Artigo Revisado por pares

Xiaoyu Xu, Nicolas A. Yannuzzi, Pedro Fernández-Avellaneda, Jose J. Echegaray, Kimberly D. Tran, Jonathan F. Russell, Nimesh A. Patel, Rehan M. Hussain, David Sarraf, K. Bailey Freund,

To introduce a simple method for differentiating retinal veins from arteries on optical coherence tomography angiography (OCTA).Cross-sectional pilot study.Four default en face slabs including color depth encoded, grayscale full-thickness retina, superficial plexus, and deep capillary plexus (DCP) from nine 3×3-mm and nine 6×6-mm OCTA scans were exported and aligned. Nine ophthalmologists with minimum OCTA experience from 2 eye institutions were instructed to classify labeled vessels as arteries or ...

Tópico(s): Retinal and Optic Conditions

2019 - Elsevier BV | American Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Ninel Z. Gregori, Jose J. Echegaray, Harry W. Flynn,

We report localized opacification of a sclera-fixated Akreos® hydrophilic acrylic intraocular lens after successful repair of rhegmatogenous retinal detachment with silicone oil tamponade in a nondiabetic patient. No intraoperative lens opacification during air-fluid exchange or lens dislocation was encountered. Granular opacities within the optic were noted at 5 months after surgery, and did not relent to scrubbing with a vitrector during oil removal. Akreos lens opacification under silicone oil ...

Tópico(s): Corneal surgery and disorders

2019 - Adis, Springer Healthcare | Ophthalmology and Therapy

Artigo Revisado por pares

Jose J. Echegaray, Yahya Alzahrani, Arun D. Singh,

Background/Aims To report visual outcomes, survival outcomes and complications following episcleral brachytherapy (EB) for retinoblastoma. Methods Retrospective review of retinoblastoma cases treated with EB in a single institution. Survival outcomes were analysed using the Kaplan-Meier method. Results Eleven tumours of 11 eyes were treated with either iodine-125 or ruthenium-106 EB with a mean apical dose of 44 Gy. The tumours were classified as group B in 5 (46%), C in 3 (27%) or D in 3 (27%) eyes, ...

Tópico(s): Head and Neck Surgical Oncology

2019 - BMJ | British Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Macarena I. de la Fuente, Juan Pablo Alderuccio, Isildinha M. Reis, Antonio Omuro, Arnold M. Markoe, Jose J. Echegaray, Janet L. Davis, J. William Harbour, Izidore S. Lossos,

Primary vitreoretinal lymphoma (PVRL) is a subset of primary CNS lymphoma that presents as isolated ocular disease without brain involvement. Although ocular radiotherapy (RT) is an effective treatment for PVRL, the optimal treatment is uncertain. PVRL may later involve the brain in 56%-85% of patients. We report on 12 PVRL patients treated with a combination of bilateral RT and a systemic chemotherapy (CT) regimen containing high-dose methotrexate (M). Ten received RT (30-40 Gy) followed by CT, one ...

Tópico(s): Glioma Diagnosis and Treatment

2019 - Wiley | American Journal of Hematology

Revisão Acesso aberto

Jose J. Echegaray, Nikolaos E. Bechrakis, Nakul Singh, Claudine Bellerive, Arun D. Singh,

To investigate whether lower radiation doses may yield similar outcome measures to those from the COMS trial.A literature review of English language articles was performed using the PubMed database of the U.S. National Library of Medicine and the Cochrane Central Register of Controlled Trials using the following keywords: uveal melanoma, choroidal melanoma, primary uveal malignant melanoma, iodine-125 brachytherapy, local recurrence, local treatment failure, and local tumor control. The relationships ...

Tópico(s): Nanoplatforms for cancer theranostics

2017 - | Ocular Oncology and Pathology

Artigo Acesso aberto Revisado por pares

Hua Gao, Peng Song, Jose J. Echegaray, Yanni Jia, Suxia Li, Man Du, Victor L. Perez, Weiyun Shi,

Objective. To evaluate the therapeutic effect of big bubble deep anterior lamellar keratoplasty (DALK) in patients with deep fungal keratitis. Methods.Consecutive patients who had DALK for deep fungal keratitis at Shandong Eye Hospital between July 2011 and December 2012 were included. In all patients, the infiltration depth was more than 4/5ths of the corneal thickness. DALK surgery was performed with bare Descemet membrane (DM) using the big bubble technique. Corrected distance visual acuity (CDVA), ...

Tópico(s): Ocular Surface and Contact Lens

2014 - Hindawi Publishing Corporation | Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Fernando Cruz‐Guilloty, Ali Saeed, Jose J. Echegaray, Stéphanie Duffort, Asha Ballmick, Yaohong Tan, Michel Betancourt, Eduardo Viteri, Ghansham C. Ramkhellawan, E. J. Ewald, William J. Feuer, Deqiang Huang, Rong Wen, Hong Li, Hua Wang, James Laird, Abdoulaye Sène, Rajendra S. Apte, Robert G. Salomon, Joe G. Hollyfield, Víctor Pérez,

Age-related macular degeneration (AMD) is a major cause of blindness in the developed world. Oxidative stress and inflammation are implicated in AMD, but precise mechanisms remain poorly defined. Carboxyethylpyrrole (CEP) is an AMD-associated lipid peroxidation product. We previously demonstrated that mice immunized with CEP-modified albumin developed AMD-like degenerative changes in the outer retina. Here, we examined the kinetics of lesion development in immunized mice and the presence of macrophages ...

Tópico(s): Retinal Development and Disorders

2013 - Hindawi Publishing Corporation | International Journal of Inflammation

Artigo Revisado por pares

Hua Gao, Xiuxian Wang, Jose J. Echegaray, Suxia Li, Ting Wang, Weiyun Shi,

Tópico(s): Ocular Surface and Contact Lens

2014 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology

Artigo Acesso aberto Revisado por pares

José Manuel Sánchez Ron,

Cuando Echegaray iba a intentar entrar en la Escuela de Caminos, se acababa de fundar una Escuela Preparatoria para las carreras de ingenieros de

Tópico(s): History, Culture, and Society

2004 - Spanish National Research Council | Arbor

Artigo Acesso aberto Revisado por pares

Jose J. Echegaray, Stephanie M. Llop, Melissa Sepulveda, Román Vélez-Rosario, Noel Perez, Armando L. Oliver,

To report a rare case of secondary intraocular lymphoma treated with intravitreal rituximab, following pars plana vitrectomy.A 74-year-old female with history of parotid gland large B-cell lymphoma presented bilateral intraocular recurrence 10 years after the onset of the primary malignancy. Systemic work-up including PET/CT Scan, bone marrow biopsy, brain MRI and CSF analysis were unremarkable, and the patient declined to undergo systemic chemotherapy. Vision loss in her left eye was severe due ...

Tópico(s): Chronic Lymphocytic Leukemia Research

2018 - Elsevier BV | American Journal of Ophthalmology Case Reports

Artigo Revisado por pares

Jose J. Echegaray, Rachel Chen, Claudine Bellerive, Arun D. Singh,

A 4-year-old female with a unilateral circumscribed choroidal hemangioma and secondary total exudative retinal detachment. A nasal skin scar-like lesion incised to confirm a histopathologic diagnosis of linear nevus sebaceous. Further imaging disclosed asymmetry of the lateral ventricle frontal horns, suggestive of the diagnosis of linear nevus sebaceous syndrome. The choroidal hemangioma was treated with I-125 episcleral brachytherapy (apical dose of 45 Gy). At 6 months post-radiation, the tumor ...

Tópico(s): Dermatological and Skeletal Disorders

2018 - Taylor & Francis | Ophthalmic Genetics

Artigo Acesso aberto

Sander R. Dubovy, Maria Paula Fernandez, Jose J. Echegaray, Norman L. Block, Noriyuki Unoki, Roberto Pérez‐Castañeda, Irving Vidaurre, Richard K. Lee, Mehrdad Nadji, Andrew V. Schally,

Extrapituitary roles for hypothalamic neurohormones have recently become apparent and clinically relevant, based on the use of synthetic peptide analogs for the treatment of multiple conditions including cancers, pulmonary edema and myocardial infarction. In the eye, it has been suggested that some of these hormones and their receptors may be present in the ciliary body, iris, trabecular meshwork and retina, but their physiological role has yet to be elucidated. Our study intends to comprehensively ...

Tópico(s): Regulation of Appetite and Obesity

2017 - Impact Journals LLC | Oncotarget

Artigo Acesso aberto Revisado por pares

Karl T. Weber, Javier Dı́ez,

... González A, Zubillaga E, Bonavila C, Bergés M, Echegaray K, Beaumont J, Moreno MU, San José G, Larman M, Querejeta R, Díez J. Myocardial ...

Tópico(s): Cardiac Fibrosis and Remodeling

2016 - Lippincott Williams & Wilkins | Circulation Heart Failure

Revisão Revisado por pares

Yusra F. Shao, Jose J. Echegaray, Nakul Singh, Arun D. Singh,

Survival of patients with uveal melanoma classified to have a bad prognosis.To explore reasons for reported variability in survival of patients with uveal melanoma classified to have a bad prognosis.We searched PUBMED, MEDLINE, and EMBASE for studies reporting survival data for uveal melanoma undergoing prognostic testing with chromosome 3 status by fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), microsatellite analysis (MSA), multiplex ligation-dependent probe amplification ( ...

Tópico(s): Corneal Surgery and Treatments

2018 - Elsevier BV | Ophthalmology Retina