Everyday a constant stream of data is generated as a result of social interactions, Internet of things, e‐commerce and other business processes. This vast amount of data should be collected, stored, transformed, monitored and analyzed in a relatively brief period of time. Reason behind is data may contain the answer to business insights and new ideas fostering competitiveness and innovation. Big Data technologies/methodologies have emerged as the solution to this need. However, being a relatively ...
Tópico(s): Digital Platforms and Economics
2013 - Halmstad University College | Journal of Intelligence Studies in Business
Iago Portela-Pino, Antonio López Castedo, Maria José Martínez‐Patiño, Teresa Valverde Esteve, José Domínguez Alonso,
A total of 852 adolescents between 12 and 17 years of age were evaluated (M = 14.86, SD = 1.67), randomly selected among a population of secondary school and Baccalaureate students. We applied an “ad hoc” questionnaire on sociodemographic data and the Self-Report of Reasons for the Practice of Physical Exercise (AMPEF) and Self-Report of Barriers to the Practice of Physical Exercise (ABPEF) questionnaires. The results obtained show a prevalence of competition, social recognition, and challenge as motivational ...
Tópico(s): Physical Activity and Health
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Estéfani García‐Ríos, María Ruiz‐Rico, José Manuel Guillamón, Édgar Pérez‐Esteve, José Manuel Barat Baviera,
Wine, as a fermented drink, is considered a microbiologically safe beverage, but the growth of spoilage microorganisms can cause economic damage. As a new preservative process, the application of immobilised essential oil components (EOCs) is proposed in this study. EOCs were attached to the surface of three different commercial supports (silica particles, cellulose particles and cellulosic membrane) to avoid the disadvantages of using these compounds in their free form, such as volatility, low water ...
Tópico(s): Fermentation and Sensory Analysis
2018 - Elsevier BV | Food Control
María‐Victoria Mateos, Lucía López‐Corral, Miguel‐Teodoro Hernández, Pilar Giraldo, Javier de la Rubia, Felipe de Arriba, Laura Rosiñol, Juan José Lahuerta, Luis Palomera, Joan Bargay, Albert Oriol, Felipe Prósper, José García‐Laraña, Eduardo Olavarría, M.L. Martino, Ana-Isabel Teruel, José‐Ángel Hernández‐Rivas, Graça Esteves, José Mariz, Fernando Leal-da-Costa, Adrián Alegre, Jose-Luis Guzman, Ana López de la Guía, Nuria Quintana, José Luis Baquero, Jose Luis Monteserin Garcia, Jesús F. San Miguel,
Tópico(s): Cancer Treatment and Pharmacology
2010 - Elsevier BV | Blood
Produção Nacional
Pedro José Labronici, Saulo Santos Blunck, Flavius Ribeiro Lana, Bruno Bandeira Esteves, José Sergio Franco, Junji Miller Fukuyama, Robinson Esteves Santos Pires,
Compare the level of vitamin D with the bone mineral density (BMD) in postmenopausal women, with or without fractures.250 women with mean age of 71.1 were evaluated. The serum levels of vitamin D considered sufficient were ≥ 30 ng/mL, insufficient between 20 and 30 ng/mL and deficient < 20 ng/mL. The bone mineral density was measured and considered osteopenia when T value total of lumbar spine or hip was between -1 and -2.5 and osteoporosis < 2.5. The patients with fractures accounted for 25.2%.There was ...
Tópico(s): Vitamin C and Antioxidants Research
2013 - Brazilian Society of Orthopedics and Traumatology | Revista Brasileira de Ortopedia (English Edition)
Miguel Sá, José Miguel Cardoso, Hugo Reis, Marta Esteves, José Sampaio, Isabel Gouveia, Pilar Carballada, Célia Pinheiro, Duarte Machado,
The quadratus lumborum block was initially described in 2007 and aims at blocking the same nerves as the ones involved on the Transverse Abdominis Plane block, while accomplishing some visceral enervation as well due to closer proximity with the neuroaxis and sympathetic trunk. Given its versatility, we have successfully used it in a wide range of procedures. We report two cases where we believe the dispersion of local anesthetic is likely to have led to a previously undescribed complication. We ...
Tópico(s): Anesthesia and Sedative Agents
2016 - Elsevier BV | Brazilian Journal of Anesthesiology (English Edition)
Miguel Sá, José Miguel Cardoso, Hugo Reis, Marta Esteves, José Sampaio, Isabel Gouveia, Pilar Carballada, Célia Pinheiro, Duarte Machado,
The quadratus lumborum block was initially described in 2007 and aims at blocking the same nerves as the ones involved on the Transverse Abdominis Plane block, while accomplishing some visceral enervation as well due to closer proximity with the neuroaxis and sympathetic trunk. Given its versatility, we have successfully used it in a wide range of procedures. We report two cases where we believe the dispersion of local anesthetic is likely to have led to a previously undescribed complication.We ...
Tópico(s): Nausea and vomiting management
2017 - Elsevier BV | Brazilian Journal of Anesthesiology
M. Mar Bernal, Francesc Marco, Álex Soriano, Manel Almela, José Antonio Martínez, Montserrat Rovira, Jordi Esteve, José Mensa,
This study was part of a bloodstream infection surveillance programme that prospectively collected data on consecutive patients with bacteraemia in our institution from 1991 to 2012. We included 2092 bacteraemias in neutropenic patients. Shock and mortality accounted for 299 and 349 cases, respectively (14% and 17%). The main microorganisms isolated were coagulase-negative staphylococci (CoNS, 634, 30%), Escherichia coli (468, 22%) and Pseudomonas aeruginosa (235, 11%). During 2006-2012, there were ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2014 - Cambridge University Press | Epidemiology and Infection
Francisco Ortega, José María Moreno‐Navarrete, Vicent Ribas, Eduardo Esteve, José Ignacio Rodríguez-Hermosa, Bartomeu Ruiz, Belén Peral, Wifredo Ricart, António Zorzano, José Manuel Fernández‐Real,
The aims of this work were to evaluate thyroid hormone receptor-alpha (TR alpha), TR alpha 1, and TR alpha 2 mRNA gene expression and TR alpha 1:TR alpha 2 ratio, identified as candidate factors for explaining regional differences between human adipose tissue depots. TR alpha, TR alpha 1, and TR alpha 2 mRNA levels, and the gene expressions of arginine-serine-rich, splicing factor 2 (SF2), heterogeneous nuclear ribonucleoprotein H1 (hnRNP H1), heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), and ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
2009 - Wiley | Obesity
Marcela Fu, Esteve Fernández, José M. Martínez-Sánchez, Noemi San Emeterio, N. Palacios Quirós, Xisca Sureda, Montse Ballbè, Glòria Muñoz, Anna Riccobene, Francesc Centrich, Esteve Saltó, María José López,
Smoke-free legislation in indoor public places has concentrated smokers in the areas outside building entrances or other outdoor areas. This study assessed the drift of second-hand smoke between outdoor and indoor areas of cafés and restaurants in Barcelona, Spain, and characterized the exposure on outdoor terraces. Using a cross-sectional design, we monitored vapor-phase nicotine in indoor areas and outside entrances simultaneously (n=47), and on some outdoor terraces (n=51). We computed the median ...
Tópico(s): Noise Effects and Management
2016 - Elsevier BV | Environmental Research
José R. López, Arkady Uryash, Gilles Faury, É. Estève, José A. Adams,
Duchenne muscular dystrophy (DMD) is an irreversible and severe muscle wasting X-linked genetic disease characterized by a progressive loss of muscle function, decreased ambulation, and ultimately death as a result of cardiac or respiratory failure. DMD is caused by the lack of dystrophin, a protein that is important for membrane stability and signaling in excitable cells. Although vascular smooth muscle cells (VSMCs) dysfunction occurs in many pathological conditions, little is known about vascular ...
Tópico(s): Exercise and Physiological Responses
2020 - Frontiers Media | Frontiers in Physiology
Francisco Ortega, Dolores Mayas, José María Moreno‐Navarrete, Victoria Catalán, Javier Gómez‐Ambrosi, Eduardo Esteve, José Ignacio Rodríguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Belén Peral, Gema Frühbeck, Francisco J. Tinahones, José Manuel Fernández‐Real,
Contradictory findings regarding the gene expression of the main lipogenic enzymes in human adipose tissue depots have been reported. In this cross-sectional study, we aimed to evaluate the mRNA expression of fatty acid synthase (FAS) and acetyl-CoA carboxilase (ACC) in omental and subcutaneous (SC) fat depots from subjects who varied widely in terms of body fat mass. FAS and ACC gene expression were evaluated by real time-PCR in 188 samples of visceral adipose tissue which were obtained during elective ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2009 - Wiley | Obesity
Juan José Esteve-Paredes, J. J. Palacios,
We present a comprehensive study of the velocity operator, \hat{\boldsymbol{v}}=\frac{i}{\hbar} [\hat{H},\hat{\boldsymbol{r}}]\, 𝐯 ̂ = i ℏ [ H ̂ , 𝐫 ̂ ] , when used in crystalline solids calculations. The velocity operator is key to the evaluation of a number of physical properties and its computation, both from a practical and fundamental perspective, has been a long-standing debate for decades. Our work summarizes the different approaches found in the literature, but never connected before in a comprehensive ...
Tópico(s): Solid-state spectroscopy and crystallography
2023 - SciPost.org | SciPost Physics Core
María Chaparro, Ana Garre, Andrea Núñez Ortiz, M T Diz-Lois Palomares, Cristina Rodríguez, Sabino Riestra, Milagros Vela, J M Benítez, Estela Fernández Salgado, Eugenia Sánchez Rodríguez, Vicent Hernández, R Ferreiro-Iglesias, Ángel Ponferrada Díaz, Jesús Barrio, José María Huguet, Beatriz Sicilia, María Dolores Martín‐Arranz, Xavier Calvet, Daniel Ginard, Inmaculada Alonso-Abreu, Luis Fernández‐Salazar, Pilar Varela Trastoy, Montserrat Rivero, Isabel Vera‐Mendoza, Pablo Vega, Pablo Navarro, Mónica Sierra, José Luis Cabriada, Mariam Aguas, Raquel Vicente, Mercè Navarro‐Llavat, Ana Echarri, Fernando Gomollón, Elena Guerra del Río, Concepción Piñero, María José Casanova, Kateřina Špičáková, Jone Ortiz de Zárate, Emilio Torrella Cortés, Ana Gutiérrez, Horacio Alonso‐Galán, Álvaro Hernández-Martínez, José Miguel Marrero, Rufo Lorente Poyatos, Margalida Calafat, Lidia Martí Romero, Pilar Robledo, Orencio Bosch, Nuria Jiménez, María Esteve, José María Duque, Ana Fuentes Coronel, Manuela Josefa Sampedro, Eva Sesé Abizanda, Belén Herreros Martínez, Liliana Pozzati, Hipólito Fernández Rosáenz, Belén Crespo Suarez, Pilar López Serrano, Alfredo J. Lucendo, Margarita Muñoz Vicente, Fernando Bermejo, José Ramírez Palanca, Margarita Menacho, Amalia Carmona, Raquel Camargo, Sandra Torrá Alsina, Nuria Maroto, Juan Nerín de la Puerta, Elena Castro, Ignacio Marín‐Jiménez, Belén Botella, Amparo Sapiña, Noelia Cruz, José Luis Fernández Forcelledo, Abdel Bouhmidi, Carlos Castańo-Milla, Verónica Opio, Isabel Nicolás, Marcos Kutz, A. Abraldes Bechiarelli, Jordi Gordillo, Yolanda Ber, Yolanda Torres Domínguez, M. Novella Durán, Silvia Rodríguez Mondéjar, Francisco J. Martínez-Cerezo, Lilyan Kolle, M Sàbat, César Ledezma, Eduardo Iyo, Óscar Roncero, Rebeca Irisarri, Laia Lluis, Isabel Blázquez Gómez, Eva Zapata, María José Fernández Alcalá, Cristina Martínez Pascual, María Montealegre, Laura Mata, Ana Monrobel, Alejandro Hernández-Camba, Luis Hernández, Marı́a Jesús Gómez de Tejada, Alberto Mir, María Luisa Galve, Marta Soler, Daniel Hervías, José Antonio Gómez-Valero, Manuel Barreiro–de Acosta, Fernando Rodríguez‐Artalejo, Esther García‐Esquinas, Javier P. Gisbert,
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 ...
Tópico(s): Pregnancy and Medication Impact
2021 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
José D. Torres‐Peña, Luis M. Pérez-Belmonte, Francisco Fuentes, Ma Dolores López Carmona, Pablo Pérez‐Martínez, José López‐Miranda, Francisco Javier Carrasco-Sánchez, Juan Antonio Vargas, Esther del Corral Beamonte, Jeffrey Óskar Magallanes Gamboa, Andrés González García, Julio González Moraleja, Andrés Cortés Troncoso, María Luisa Taboada Martínez, María del Pilar del Fidalgo Montero, José Miguel Seguí Ripol, Ricardo Gil Sánchez, Diana Alegre González, Ramón Boixeda, Begoña Cortés Rodríguez, Javier Ena, Gema María García García, Ana Ventura Esteve, José Manuel Ramos, Ricardo Gómez‐Huelgas,
Tópico(s): Long-Term Effects of COVID-19
2021 - Adis, Springer Healthcare | Drugs
Xisca Sureda, José M. Martínez-Sánchez, Marcela Fu, Raúl Pérez‐Ortuño, Cristina Martínez, Esther Carabasa, María José López, Esteve Saltó, José A. Pascual, Esteve Fernández,
Background In 2006, Spain implemented a national smoke-free legislation that prohibited smoking in enclosed public places and workplaces (except in hospitality venues). In 2011, it was extended to all hospitality venues and selected outdoor areas (hospital campuses, educational centers, and playgrounds). The objective of the study is to evaluate changes in exposure to secondhand smoke among the adult non-smoking population before the first law (2004-05) and after the second law (2011–12). Methods Repeated ...
Tópico(s): Air Quality and Health Impacts
2014 - Public Library of Science | PLoS ONE
José M. Martínez-Sánchez, Xisca Sureda, Marcela Fu, Raúl Pérez‐Ortuño, Montse Ballbè, María José López, Esteve Saltó, José A. Pascual, Esteve Fernández,
We assessed and characterized the relationship among biomarkers of secondhand smoke (SHS) exposure in non-smokers according to their exposure at home as measured by airborne markers. We conducted an observational study on exposure to SHS at home using airborne markers (nicotine and benzene) and biomarkers from the non-smokers living in these homes. We selected 49 non-smoking volunteers from different homes: 25 non-smokers living with at least one smoker and 24 non-smokers living in smoke-free homes. ...
Tópico(s): Noise Effects and Management
2014 - Elsevier BV | Environmental Research
S. Catalan, L. Cadarso, Flavia Maria Esteves, José Salgado‐Borges, M. Lopez, Carmén Cadarso-Suárez,
Purpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n = 22) and normal fellow eyes (n = 22) in patients with asymmetric keratoconus and normal eyes (n = 104) in healthy subjects. Areas under the curve (AUC) of receiver operator characteristic (ROC) curves for each variable ...
Tópico(s): Glaucoma and retinal disorders
2016 - Hindawi Publishing Corporation | Journal of Ophthalmology
Vicent Esteve, José Thiers Carneiro, Fátima Moreno, Miquel Fulquet, Salud Garriga, Mónica Pou, Verónica Duarte, Anna Saurina, Irati Tapia, Manel Ramírez de Arellano,
Haemodialysis (HD) patients are characterised by significant muscle loss. Recently, neuromuscular electrical stimulation (NMES) has emerged as a new therapeutic alternative to improve these patients' physical condition. To date, no studies on the effects of NMES on body composition in HD patients have been published.To analyse the effect of NMES on muscle strength, functional capacity and body composition in our HD patients.A 12-week, single-centre, prospective study. The patients were assigned to ...
Tópico(s): Medical research and treatments
2016 - Elsevier BV | Nefrología
Sergio Morales‐Torres, Carla M.P. Esteves, José L. Figueiredo, Adrián M.T. Silva,
Polysulfone (PSf) membrane supports were blended with pristine multi-walled carbon nanotubes (MWCTNs), functionalized MWCNTs (MWf), graphene oxide (GO) and their corresponding carbon-TiO2 composites. The surface hydrophilicity and the porous structure of the supports depended markedly on loading, type and surface chemistry of the nanostructured material, as well as on the addition or not of polyvinylpyrrolidone (PVP). These PSf supports were used to develop polyamide thin-film composite (TFC) membranes, ...
Tópico(s): Nanopore and Nanochannel Transport Studies
2016 - Elsevier BV | Journal of Membrane Science
Produção Nacional
Revisado por pares
Paulo Emílio Corrêa Leite, Mariana Rodrigues Pereira, Carlos Antônio do Nascimento Santos, Andréa Campos, Ticiana Mota Esteves, José Mauro Granjeiro,
Gold nanoparticles (AuNP) have been widely used for many applications, including as biological carriers. A better understanding concerning AuNP safety on muscle cells is crucial, since it could be a potential tool in the nanomedicine field. Here, we describe the impact of polyethylene glycol-coated gold nanoparticles (PEG-AuNP) interaction with differentiated skeletal muscle C2C12 cells on cell viability, mitochondria function, cell signaling related to survival, cytokine levels and susceptibility ...
Tópico(s): Advanced Nanomaterials in Catalysis
2015 - Elsevier BV | Toxicology in Vitro
Produção Nacional
Margarida Figueiredo, Larissa Sapucaia Ferreira Esteves, José Neves, Henrique Vicente,
This study reports the use of data mining tools in order to examine the influence of the methodology used in chemistry lab classes, on the weight attributed by the students to the lab work on learning and own motivation. The answer frequency analysis was unable to discriminate the opinions expressed by the respondents according to the type of the teaching methodology used in the lab classes. Conversely, the data mining approach using k -means clustering models, allowed a deeper analysis of the results, ...
Tópico(s): Innovative Teaching and Learning Methods
2015 - Royal Society of Chemistry | Chemistry Education Research and Practice
Rajiv Agarwal, Wanzhu Tu, Alfredo E. Farjat, Youssef M.K. Farag, Robert D. Toto, Sanjay Kaul, Robert Lawatscheck, Katja Rohwedder, Luís M. Ruilope, Peter Rossing, Bertram Pitt, Gerasimos Filippatos, Stefan D. Anker, George L. Bakris, Augusto Vallejos, Richard J. MacIsaac, Guntram Schernthaner, Pieter Gillard, Maria Eugênia Fernandes Canziani, Theodora Temelkova‐Kurktschiev, Ellen Burgess, Sheldon W. Tobe, Fernando González, Zhihong Liu, Andrés Ángelo Cadena Bonfanti, Carlos Jaramillo, Martin Prázný, Jorma Strand, Michel Marre, Roland E. Schmieder, Christoph Wanner, Pantelis Sarafidis, Juliana C.N. Chan, László Rosivall, Joseph A. Eustace, Ehud Grossman, Yoram Yagil, Giuseppe Remuzzi, Daisuke Koya, Takashi Wada, Magdalena Madero Rovalo, Ron T. Gansevoort, Adriaan Kooy, Trine Finnes, Froilan DeLeon, Janusz Gumprecht, Fernando Teixeira e Costa, Alexander Dreval, Anantharaman Vathsala, Aslam Amod, Sin Gon Kim, Byung‐Wan Lee, Julio Pascual Santos, Bengt-Olov Tengmark, Michel Burnier, Chien‐Te Lee, Sukit Yamwong, Ramazan Sarı, Kieran McCafferty, Borys Mankovsky, Sharon G. Adler, Linda F. Fried, Mark V. Williams, Tran Quang Khanh, Diego Aizenberg, Inés Bartolacci, Diego Besada, Julio Bittar, Mariano Chahin, Alicia Elbert, Elizabeth Gelersztein, Alberto Liberman, Laura Maffei, Federico Pérez Manghi, Hugo Sanabria, Gloria Viñes, Alfredo Wassermann, Walter P. Abhayaratna, Shamasunder Acharya, Elif I. Ekinci, Darren Lee, Peak Mann Mah, Craig Nelson, David Packham, Alexia Pape, Simon D. Roger, Hugo Stephenson, Michael Suranyi, Gary Wittert, Elizabeth Vale, Martin Clodi, Christoph Ebenbichler, Evelyn Fließer-Görzer, Ursula Hanusch, Michael Krebs, Karl Lhotta, Bernhard Ludvik, Gert Mayer, Peter Neudorfer, Bernhard Paulweber, Rudolf Prager, Wolfgang Preiß, Friedrich C. Prischl, G. Schernthaner, Harald Sourij, Martin Wiesholzer, Peter Doubel, W. Engelen, Pieter Gillard, Jean‐Michel Hougardy, Jean-Marie Krzesinski, Bart Maes, Marijn M. Speeckaert, Koen Stas, Luc Van Gaal, Hilde Vanbelleghem, Daniela Antunes, Roberto Botelho, Cláudia Brito, Luís Henrique Santos Canani, Maria Eugênia Fernandes Canziani, Maria Cerqueira, Rogério de Paula, Freddy G. Eliaschewitz, Carlos Eduardo Poli‐de‐Figueiredo, Adriana Costa e Forti, Miguel Nasser Hissa, Maurilo Leite, Emerson de Lima, Irene L. Noronha, Bruno Paolino, Nathalia Paschoalin, Raphael Paschoalin, Roberto Pécoits-Filho, Marcio Pereira, Evandro Portes, Dalton Bertolim Précoma, Rosângela Réa, Miguel C. Riella, João Eduardo Nunes Salles, Eduardo Vasconcellos, Sérgio Vencio, Paul E. Barré, Brian Carlson, James Conway, Serge Cournoyer, R Dumas, Sameh Fikry, Richard Goluch, Pavel Hamet, Randolph Hart, Sam Henein, Joanne Liutkus, François Madore, Valdemar Martinho, Giuseppe Mazza, Philip A. McFarlane, Dennis O’ Keefe, Sean D. Peterson, Daniel Schwartz, Daniel Shu, Andrew Steele, Guy Tellier, Karthik Tennankore, Sheldon W. Tobe, George Tsoukas, Richard Tytus, Louise Vitou, Michael Walsh, S. John Weisnagel, Igor Wilderman, Jean‐François Yale, Jorge Cobos, Juan Godoy, Fernando González, Sergio Lobos, Juan Carlos Palma, Juan Carlos Prieto, Eliana Reyes, Carmen Romero, Víctor Saavedra, Mario Vega, Ruifang Bu, Cai H, Nan Chen, Qinkai Chen, Dejun Chen, Jinluo Cheng, Youping Dong, Junwu Dong, Tianjun Guan, Chuan‐Ming Hao, Wen Huang, Fangfang Jiang, Minxiang Lei, Ling Li, Zhonghe Li, Xuemei Li, Jingmei Li, Yan Li, Xinling Liang, Bo Liang, Fang Liu, Yinghong Liu, Yuan-Tao Liu, Zhihong Liu, Gang Long, Guoyuan Lu, Weiping Lu, Yibing Lu, Ping Luo, Jianhua Ma, Zhaohui Mo, Jianying Niu, Ai Peng, Jiansong Shen, Feixia Shen, Bingyin Shi, Qing Su, Zhuxing Sun, Shuifu Tang, Nanwei Tong, Hao Wang, Xinjun Wang, Lihua Wang, Guixia Wang, Jianqin Wang, Yangang Wang, Li Wang, Jiali Wei, Tianfeng Wu, Chao-Qing Wu, Xing Changying, Fei Xiong, Xudong Xu, Ning Xu, Tiekun Yan, Jinkui Yang, Aiping Yin, Longyi Zeng, Hao Zhang, Yanlin Zhang, Ying Zhang, Wenjing Zhao, Zhiquan Zhao, Hongguang Zheng, Ling Zhong, Dalong Zhu, Yongze Zhuang, Clara Arango, Sandra Barrera, Nelly Beltrán López, Diego Benitez, Guillermo Blanco, Andrés Cadena, Julián Coronel, Carlos Cure, Carlos Durán, Alexander Ariel Padrón González, Gustavo Guzmán, Eric Hernández, Jaime Ibarra, Carlos Jaramillo, Nicolás Jaramillo, William Kattah, Dora I. Molina, Gregorio Sánchez, Mónica Terront, Freddy Trujillo, Miguel Urina‐Triana, Ruben Vargas, Iván Villegas, Hernán Yupanqui, D Alferi, Michal Brada, Jiri Brezina, Petr Bucek, Tomáš Edelsberger, Drahomira Gulakova, J Zapletalová, Olga Hola, Lucie Hornova, Jana Houdova, Helena Hrmova, David Karásek, Sarka Kopecka, Richard Kovar, Eva Krčová, Jiří Kuchař, Vlasta Kutejova, H Lubanda, Ivo Matyasek, Magdaléna Mokrejšová, Libor Okenka, Martin Prázný, Jiri Pumprla,
In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown.
American College of Physicians
Héctor Gómez-Llorente, Pau Hervás, Édgar Pérez‐Esteve, José Manuel Barat Baviera, Isabel Fernández‐Segovia,
The purpose of this work was to evaluate Spanish consumers' opinions on using nanotechnology in food processing and packaging. For this purpose, a literature review was carried out in the main research database to determine the most widespread uses of nanotechnology in the food industry and the most promising developments. Of all the nanotechnology uses in food, five areas of application were identified: developing new ingredients or additives, formulating new antimicrobial systems, and designing ...
Tópico(s): Consumer Packaging Perceptions and Trends
2022 - Elsevier BV | NanoImpact
Peter Rossing, Ellen Burgess, Rajiv Agarwal, Stefan D. Anker, Gerasimos Filippatos, Bertram Pitt, Luís M. Ruilope, Pieter Gillard, Richard J. MacIsaac, Julio Wainstein, Amer Joseph, Meike Brinker, Lothar Roessig, Charlie Scott, George L. Bakris, Augusto Vallejos, Richard J. MacIsaac, Guntram Schernthaner, Pieter Gillard, Maria Eugênia Fernandes Canziani, Theodora Temelkova‐Kurktschiev, Ellen Burgess, Sheldon W. Tobe, Fernando González, Zhihong Liu, Andrés Ángelo, Cadena Bonfanti, Carlos Jaramillo, Martin Prázný, Peter Rossing, Jorma Strand, Michel Marre, Roland E. Schmieder, Christoph Wanner, Pantelis Sarafidis, Juliana C.N. Chan, László Rosivall, Joseph A. Eustace, Ehud Grossman, Yoram Yagil, Giuseppe Remuzzi, Daisuke Koya, Takashi Wada, Magdalena Madero Rovalo, Ron T. Gansevoort, Adriaan Kooy, Trine Finnes, Froilan De Leon, Janusz Gumprecht, Fernando Teixeira e Costa, Alexander Dreval, Anantharaman Vathsala, Aslam Amod, Sin Gon Kim, Byung‐Wan Lee, Julio Pascual Santos, Bengt-Olov Tengmark, Michel Burnier, Chien‐Te Lee, Sukit Yamwong, Ramazan Sarı, Kieran McCafferty, Borys Mankovsky, Sharon G. Adler, Linda P. Fried, Robert Toto, Mark V. Williams, Tran Quang Khanh, Diego Aizenberg, Inés Bartolacci, Diego Besada, Julio Bittar, Mariano Chahin, Alicia Elbert, Elizabeth Gelersztein, Alberto Liberman, Laura Maffei, Federico Pérez Manghi, Hugo Sanabria, Gloria Viñes, Alfredo Wassermann, Walter P. Abhayaratna, Shamasunder Acharya, Elif I. Ekinci, Darren Lee, Peak Mann Mah, Craig Nelson, David Packham, Alexia Pape, Simon D. Roger, Hugo Stephenson, Michael Suranyi, Gary Wittert, Elizabeth Vale, Martin Clodi, Christoph Ebenbichler, Evelyn Fließer-Görzer, Ursula Hanusch, Michael Krebs, Karl Lhotta, Bernhard Ludvik, Gert Mayer, Peter Neudorfer, Bernhard Paulweber, Rudolf Prager, Wolfgang Preiß, Friedrich C. Prischl, G. Schernthaner, Harald Sourij, Martin Wiesholzer, Peter Doubel, W. Engelen, Jean‐Michel Hougardy, Jean-Marie Krzesinski, Bart Maes, Marijn M. Speeckaert, Koen Stas, Luc Van Gaal, Hilde Vanbelleghem, Daniela Antunes, Roberto Botelho, Cláudia Brito, Luís Henrique Santos Canani, Maria Eugênia Fernandes Canziani, Maria Cerqueira, Rogério de Paula, Freddy G. Eliaschewitz, Carlos Eduardo Poli‐de‐Figueiredo, Adriana Costa e Forti, Miguel Nasser Hissa, Maurilo Leite, Emerson de Lima, Irene L. Noronha, Bruno Paolino, Nathalia Paschoalin, Raphael Paschoalin, Roberto Pécoits-Filho, Marcio Pereira, Evandro Portes, Dalton Bertolim Précoma, Rosângela Réa, Miguel C. Riella, João Eduardo Nunes Salles, Eduardo Vasconcellos, Sérgio Vencio, Emiliya Apostolova, Radostina Boshnyashka, Ghassan Farah, Dimitar Georgiev, Valentina Gushterova, Neli Klyuchkova, Mariya Lucheva, Petya Manova, Dotska Minkova, Boyan Nonchev, Mariyana Pichmanova, Zhulieta Prakova, Rangel Rangelov, Rosen Rashkov, Pavel Stanchev, Bilyana Stoyanovska-Elencheva, Zhivko Tagarev, Theodora Temelkova-Kurktschieva, S Vasileva, Mariana Yoncheva-Mihaylova, Paul E. Barré, Brian Carlson, James Conway, Serge Cournoyer, R Dumas, Sameh Fikry, Richard Goluch, Pavel Hamet, Randolph Hart, Sam Henein, Joanne Liutkus, François Madore, Valdemar Martinho, Giuseppe Mazza, Philip A. McFarlane, Dennis D. O’Keefe, Sean Peterson, Daniel M. Schwartz, Daniel Shu, Andrew Steele, Guy Tellier, Karthik Tennankore, George Tsoukas, Richard Tytus, Louise Vitou, Michael Walsh, S. John Weisnagel, Igor Wilderman, Jean‐François Yale, Jorge Cobos, Juan Godoy, Sergio Lobos, Juan Carlos Palma, Juan Carlos Prieto, Eliana Reyes, Carmen Romero, Víctor Saavedra, Mario Vega, Ruifang Bu, Cai H, Nan Chen, Qinkai Chen, Dejun Chen, Jinluo Cheng, Youping Dong, Junwu Dong, Tianjun Guan, Chuan‐Ming Hao, Wen Huang, Fangfang Jiang, Minxiang Lei, Ling Li, Zhonghe Li, Xuemei Li, Jingmei Li, Yan Li, Xinling Liang, Bo Liang, Fang Liu, Yinghong Liu, Yuan-Tao Liu, Zhihong Liu, Gang Long, Guoyuan Lu, Weiping Lu, Yibing Lu, Ping Luo, Jianhua Ma, Zhaohui Mo, Jianying Niu, Ai Peng, Jiansong Shen, Feixia Shen, Bingyin Shi, Qing Su, Zhuxing Sun, Shuifu Tang, Nanwei Tong, Hao Wang, Xinjun Wang, Lihua Wang, Guixia Wang, Jianqin Wang, Yangang Wang, Li Wang, Jiali Wei, Tianfeng Wu, Chao-Qing Wu, Xing Changying, Fei Xiong, Xudong Xu, Ning Xu, Tiekun Yan, Jin‐Kui Yang, Aiping Yin, Longyi Zeng, Hao Zhang, Yanlin Zhang, Ying Zhang, Wenjing Zhao, Zhiquan Zhao, Hongguang Zheng, Ling Zhong, Dalong Zhu, Yongze Zhuang, Clara Arango, Sandra Barrera, Nelly Beltrán López, Diego Benitez, Guillermo Blanco, Andrés Cadena, Julián Coronel, Carlos Cure, Carlos Durán, Alexander Ariel Padrón González, Gustavo Guzmán, Eric Hernández, Jaime Ibarra, Carlos Jaramillo, Nicolás Jaramillo, William Kattah, Dora I. Molina, Gregorio Sánchez, Mónica Terront, Freddy Trujillo, Miguel Urina‐Triana, Ruben Vargas, Iván Villegas, Hernán Yupanqui, D Alferi, Michal Brada,
Finerenone significantly improved cardiorenal outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial. We explored whether baseline HbA1c level and insulin treatment influenced outcomes.Patients with T2D, urine albumin-to-creatinine ratio (UACR) of 30-5,000 mg/g, estimated glomerular filtration rate (eGFR) of 25 to <75 mL/min/1.73 m2, and treated with optimized renin-angiotensin ...
American Diabetes Association
Peter Rossing, Stefan D. Anker, Gerasimos Filippatos, Bertram Pitt, Luís M. Ruilope, Andreas L. Birkenfeld, Janet B. McGill, Sylvia E. Rosas, Amer Joseph, Martin Gebel, Luke Roberts, Markus F. Scheerer, George L. Bakris, Rajiv Agarwal, Diego Aizenberg, Inés Bartolacci, Diego Besada, Julio Bittar, Mariano Chahin, Alicia Elbert, Elizabeth Gelersztein, Alberto Liberman, Laura Maffei, Federico Pérez Manghi, Hugo Sanabria, Augusto Vallejos, Gloria Viñes, Alfredo Wassermann, Walter P. Abhayaratna, Shamasunder Acharya, Elif I. Ekinci, Darren Lee, Richard J. MacIsaac, Peak Mann Mah, Craig Nelson, David Packham, Alexia Pape, Simon D. Roger, Hugo Stephenson, Michael Suranyi, Gary Wittert, Elizabeth Vale, Peter G. Colman, David Colquhoun, Chris Ellis, Kim Joshua, Eugenia Pedagogos, Paul Regal, Duncan J. Topliss, James Vandeleur, Johan Verjans, Gary Wittert, Katie-Jane Wynne, Martin Clodi, Christoph Ebenbichler, Evelyn Fließer-Görzer, Ursula Hanusch, Michael Krebs, Karl Lhotta, Bernhard Ludvik, Gert Mayer, Peter Neudorfer, Bernhard Paulweber, Rudolf Prager, Wolfgang Preiß, Friedrich C. Prischl, G. Schernthaner, Harald Sourij, Martin Wiesholzer, Heinz Drexel, Rainer Oberbauer, Hans‐Robert Schönherr, Peter Doubel, W. Engelen, Pieter Gillard, Jean‐Michel Hougardy, Jean-Marie Krzesinski, Bart Maes, Marijn M. Speeckaert, Koen Stas, Luc Van Gaal, Hilde Vanbelleghem, Francis Duyck, André Scheen, Daniela Antunes, Roberto Botelho, Cláudia Brito, Luís Henrique Santos Canani, Maria Eugênia Fernandes Canziani, Maria Cerqueira, Rogério de Paula, Freddy G. Eliaschewitz, Carlos Eduardo Poli‐de‐Figueiredo, Adriana Costa e Forti, Miguel Nasser Hissa, Maurilo Leite, Emerson de Lima, Irene L. Noronha, Bruno Paolino, Nathalia Paschoalin, Raphael Paschoalin, Roberto Pécoits-Filho, Marcio Pereira, Evandro Portes, Dalton Bertolim Précoma, Rosângela Réa, Miguel C. Riella, João Eduardo Nunes Salles, Eduardo Vasconcellos, Sérgio Vencio, Marcelo Rodrigues Bacci, Lília Nigro Maia, Aline Sterque Villacorta, Emiliya Apostolova, Radostina Boshnyashka, Ghassan Farah, Dimitar Georgiev, Valentina Gushterova, Neli Klyuchkova, Mariya Lucheva, Petya Manova, Dotska Minkova, Boyan Nonchev, Mariyana Pichmanova, Zhulieta Prakova, Rangel Rangelov, Rosen Rashkov, Pavel Stanchev, Bilyana Stoyanovska-Elencheva, Zhivko Tagarev, Theodora Temelkova-Kurktschieva, S Vasileva, Mariana Yoncheva-Mihaylova, Angel Marinchev, Mariya Miteva, Paul E. Barré, Brian Carlson, James Conway, Serge Cournoyer, R Dumas, Sameh Fikry, Richard Goluch, Pavel Hamet, Randolph Hart, Sam Henein, Joanne Liutkus, François Madore, Valdemar Martinho, Giuseppe Mazza, Philip A. McFarlane, Dennis D. O’Keefe, Sean D. Peterson, Daniel Schwartz, Daniel Shu, Andrew Steele, Guy Tellier, Karthik Tennankore, Sheldon W. Tobe, George Tsoukas, Richard Tytus, Louise Vitou, Michael Walsh, S. John Weisnagel, Igor Wilderman, Jean‐François Yale, Fadia El Boreky, Alan Kelly, Lawrence A. Leiter, Ivor Teitelbaum, Jorge Cobos, Juan Godoy, Fernando González, Sergio Lobos, Juan Carlos Palma, Juan Carlos Prieto Dominguez, Eliana Reyes, Carmen Romero, Víctor Saavedra, Mario Vega, Marcelo Gabriel Medina, Paola Varleta, Ruifang Bu, Cai H, Nan Chen, Qinkai Chen, Dejun Chen, Jinluo Cheng, Youping Dong, Junwu Dong, Tianjun Guan, Chuan‐Ming Hao, Wen Huang, Fangfang Jiang, Minxiang Lei, Ling Li, Zhonghe Li, Xuemei Li, Jingmei Li, Yan Li, Xinling Liang, Bo Liang, Fang Liu, Yinghong Liu, Yuantao Liu, Zhihong Liu, Gang Long, Guoyuan Lu, Weiping Lu, Yibing Lu, Ping Luo, Jianhua Ma, Zhaohui Mo, Jianying Niu, Ai Peng, Jiansong Shen, Feixia Shen, Bingyin Shi, Qing Su, Zhuxing Sun, Shuifu Tang, Nanwei Tong, Hao Wang, Xinjun Wang, Guixia Wang, Jianqin Wang, Yangang Wang, Li Wang, Jiali Wei, Tianfeng Wu, Chao-Qing Wu, Xing Changying, Fei Xiong, Xudong Xu, Ning Xu, Tiekun Yan, Jinkui Yang, Aiping Yin, Longyi Zeng, Hao Zhang, Yanlin Zhang, Ying Zhang, Wenjing Zhao, Zhiquan Zhao, Hongguang Zheng, Ling Zhong, Dalong Zhu, Yongze Zhuang, Yuming Du, Yi Fang, Weiying Guo, Sheng Jiang, Jian Kuang, Dongmei Li, Hongmei Li, Yinan Li, Yuxiu Li, Liu Jian, Yu Liu, Heng Miao, Wen Peng, Lihua Wang, Mingtong Xu, Liyong Zhong, Jun Zhu, Clara Arango, Sandra Barrera, Nelly Beltrán López, Diego Benitez, Guillermo Blanco, Andrés Cadena, Julián Coronel, Carlos Cure, Carlos E. Durán, Alexander Ariel Padrón González, Gustavo Guzmán, Eric Hernández, Jaime Ibarra, Carlos Jaramillo, Nicolás Jaramillo, William Kattah, Dora I. Molina, Gregorio Sánchez, Mónica Terront, Freddy Trujillo, Miguel Urina‐Triana, Ruben Vargas, Iván Villegas, Hernán Yupanqui, Édgar Arcos, Gustavo Aroca, Germán Barreto, Andrés Bermúdez, Rodrigo Botero, Tatiana Cárdenas, Wilmer Figueroa, Mónica Jaramillo,
Finerenone reduced the risk of kidney and cardiovascular events in people with chronic kidney disease (CKD) and type 2 diabetes in the FIDELIO-DKD and FIGARO-DKD phase 3 studies. Effects of finerenone on outcomes in patients taking sodium-glucose cotransporter 2 inhibitors (SGLT2is) were evaluated in a prespecified pooled analysis of these studies.Patients with type 2 diabetes and urine albumin-to-creatinine ratio (UACR) ≥30 to ≤5,000 mg/g and estimated glomerular filtration rate (eGFR) ≥25 mL/min/1.73 ...
American Diabetes Association
Francisco Esteves, José Rueff, Michel Kranendonk,
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxygenases play a pivotal role in the detoxification of xenobiotics, participating in the metabolism of many structurally diverge compounds. This short-review is intended to provide a summary on the major roles of CYPs in Phase I xenobiotic metabolism. The ...
Tópico(s): Computational Drug Discovery Methods
2021 - PAGEPress (Italy) | Journal of Xenobiotics
Produção Nacional
Thiago de Jesus Esteves, José dos Santos Souza,
O artigo tem como objeto de análise o processo de transformação do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (INEP) em agência de avaliação da educação brasileira no contexto das reformas gerenciais implementadas a partir do governo de Fernando Henrique Cardoso (1995-2002) e aperfeiçoadas pelos governos de Lula da Silva (2003-2010) e Dilma Roussef (2011-2016). Seu objetivo é evidenciar o papel do INEP na reforma gerencial da educação. A promulgação da Lei nº 9.394/1996, ...
Tópico(s): Academic Research in Diverse Fields
2020 - | Educere et Educare
Damián Valverde García, Édgar Pérez‐Esteve, José Manuel Barat Baviera,
Abstract Alkalization, also known as “Dutching,” is an optional, but very useful, step taken in the production chain of cocoa to darken its color, modify its taste, and increase natural cocoa solubility. Over the years, various attempts have been made to design new and more effective alkalization methods. Moreover, different authors have attempted to elucidate the impact of alkalization on the physicochemical, nutritional, functional, microbiological, and sensory characteristics of alkalized cocoa. ...
Tópico(s): Proteins in Food Systems
2020 - Wiley | Comprehensive Reviews in Food Science and Food Safety
Produção Nacional
Revisado por pares
Natália E. C. de Almeida, Franciele Grego Esteves, José Roberto Aparecido dos Santos‐Pinto, Carla Peres de Paula, Anderson Ferreira da Cunha, Iran Malavazi, Mário Sérgio Palma, Edson Rodrigues‐Filho,
Celiac disease (CD) is a chronic illness characterized by an inflammatory process triggered by gluten protein intake. Recent evidence has suggested that the lower relative abundance of bifidobacteria in the intestinal lumen may be associated with CD. Herein, we assessed the effect of the Bifidobacterium species Bifidobacterium bifidum, Bifidobacterium longum, Bembidion breve, Bifidobacterium animalis alone, and also a Bifidobacterium consortium on the digestion of intact gluten proteins (gliadins ...
Tópico(s): Microscopic Colitis
2020 - American Chemical Society | Journal of Agricultural and Food Chemistry