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Primary Document Acesso aberto

Antonio Ramírez,

Pressmark Cup. 405 g.2 (32) Book.

1835 - Gale Group | World Scholar Latin America

Artigo Revisado por pares

Ricardo Aroca, Juan Manuel Ruíz-Lozano, Ángel M. Zamarreño, José Antonio Souto Paz, José Maria García‐Mina, Marı́a J. Pozo, Juan A. López‐Ráez,

Arbuscular mycorrhizal (AM) symbiosis can alleviate salt stress in plants. However the intimate mechanisms involved, as well as the effect of salinity on the production of signalling molecules associated to the host plant-AM fungus interaction remains largely unknown. In the present work, we have investigated the effects of salinity on lettuce plant performance and production of strigolactones, and assessed its influence on mycorrhizal root colonization. Three different salt concentrations were applied ...

Tópico(s): Mycorrhizal Fungi and Plant Interactions

2012 - Elsevier BV | Journal of Plant Physiology

Primary Document Acesso aberto

José María Paz,

Pressmark Cup. 405 b.36 Book.

1848 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

Rafael Borge, Daeun Jung, Iciar Lejarraga, David de la Paz, José María Cordero,

According to the Air Quality (AQ) Directive (2008/50/EC), European Member States should establish (and revise every five years) their own AQ zones, where the air quality and population exposure are homogeneous. In Madrid, there are currently seven AQ zones, which were determined based on administrative geographic and land use criteria in 2014. However, so far, there has been no standardized methodology to define an objective AQ zoning. In this study, a new methodology is applied to revise the AQ zones ...

Tópico(s): Atmospheric chemistry and aerosols

2022 - Elsevier BV | Atmospheric Environment

Primary Document Acesso aberto

José María Paz,

Pressmark Cup. 405 g.2 (7) Book.

1829 - Gale Group | World Scholar Latin America

Revisão Revisado por pares

María Paz Sánchez‐Seco, José María Navarro,

Las arbovirosis, infecciones virales transmitidas por artrópodos, son un problema de salud de ámbito mundial. La reaparición de brotes de algunas de ellas, como el dengue o la encefalitis por el virus del Nilo occidental, en regiones en las que no son habituales, justifica la necesidad de establecer medidas globales para su control. En Europa, las arbovirosis más frecuentes son: encefalitis transmitida por garrapatas (Tick borne encephalitis [TBE]), fiebre transmitida por flebotomos (sand fly fever ...

Tópico(s): Viral Infections and Outbreaks Research

2005 - Elsevier BV | Enfermedades Infecciosas y Microbiología Clínica

Jornais Acesso aberto

FROM OUR SPECIAL CORRESPONDENT., FROM OUR NEWMARKET CORRESPONDENT., FROM OUR CRICKET CORRESPONDENT., From Our Special Correspondents., FROM OUR CORRESPONDENT., By CALLISTHENES., BY A MILITARY CORRESPONDENT., FROM A CORRESPONDENT., FROM OUR OWN CORRESPONDENT., FROM OUR CORRESPONDENT AT GENEVA., From Our Labour Correspondent., From Our Special Correspondent., G. W. HOLMES., J. A. R. MARRIOTT., L. P. WINBY., W. HOWARD HAZELL., C. H. P. MAYO., W. MOORE EDE., MURRAY F. SUETER., A MOTORIST OF MORE THAN August 8. 500, 000 MILES., J. A. GIBB., FROM OUR CHESS CORRESPONDENT., A correspondent, From Our Madrid Correspondent., By JOSÉ MARIA GONZALEZ., By R. Ruiz Ferry., FROM A CORRESPONDENT IN SEVILLE., By RAMON HERNANDEZ MATEOS, From a Spanish Correspondent., By JOSÉ CALVO SOTELO, BY OUR OWN CORRESPONDENT., By J. H. PERRY., By L. E. ELLIOTT., By AUBREY F. G. BELL., FROM A CORRESPONDENT IN SPAIN., By SEVERIANO VEGA DE SEOANE, BY CARLOS MENDOZA., By H. T. CORY, By CARLOS POSADA., By Professor R. CARANDE, By JULIO LOPEZ OLIVAN., By THE DUKE OF ALBA., By W. G. CASS., By Brig.-General G. V. CLARKE., FROM OUR MADRID CORRESPONDENT., By E. CUNARD., By F. MARTÍN-SANCHEZ JULIÁ., By LUIS GARCIA GUIJARRO., By MARCELINO DE ARANA, By JOSÉ CASTILLEJO., By F. RESTREPO, S.J., By "BEATRIZ GALINDO.", By RAMIRO DE MAEZTU., By J. B. TREND., By SIR CHARLES BEDFORD, By JOAQUIN DE ZUAZAGOITIA., By Dr. JOSÉ M. GIL ROBLES., By Professor ELIAS TORMO, By MILDRED STAPLEY BYNE., By Professor L. JORDANA., By the MARQUIS MERRY DEL VAL., By ADOLFO POSADA., De nuestro corresponsal en Madrid., DE UN CORRESPONSAL., Por DON JOSÉ MARIA GONZALEZ, Por DON RICARDO RUÍZ FERRY., DE UN CORRESPONSAL EN SEVILLA., POR UN CORRESPONSAL., Por DON RAMÓN HERNÁNDEZ MATEOS, Ingeniero Civil., De un Corresponsal Español., Por Don JOSÉ CALVO SOTELO., DE NUESTRO CORRESPONSAL., Por J. H. PERRY., Por L. E. ELLIOTT., Por AUBREY F. G. BELL., DE UN CORRESPONSAL EN ESPAÑA., Por DON SEVERIANO VEGA DE SEOANE, Ingeniero de Minas., Por DON CARLOS MENDOZA, Por H. T. CORY, Por DON CARLOS POSADA., Por el Profesor R. CARANDE., Por DON JULIO LÓPEZ OLIVÁN, , Por el DUQUE DE ALBA., Por W. G. CASS., Por el GENERAL G. V. CLARKE, DE NUESTRO CORRESPONSAL EN MADRID., Por E. CUNARD., Por DON F. MARTÍN SANCHEZ JULIÁ, Ingeniero Agronomo., Por DON LUIS GARCÍA GUIJARRO., Por DON MARCELINO ARANA., Por DON LUIS GARCIA GUIJARRO., Por DON JOSÉ CASTILLEJO., Por el PADRE F. RESTREPO., Por, , BEATRIZ GALINDO.", Por DON RAMIRO DE MAEZTU., Por J. B. TREND., Por SIR CHARLES BEDFORD, Por DON JOAQUÍN DE ZUAZAGOITIA., Por DON JOSÉ M. GIL DE ROBLES, Por DON ELLAS TORMO, Por MILDRED STAPLEY BYNE., Por el Profesor L. JORDANA, Por el MARQUÉS DE MERRY DEL VAL., Por, , BEATRIZ GALINDO.", Por DON ADOLFO POSADA.,

Births. Marriages. Deaths. Classified Advertising: Transfer Books., Road Transport., London Hotels, Domestic Situations Vacant, Entertainments Index., ...

1926 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Mario Fernández‐Ruiz, Francisco López‐Medrano, E Romo, Luis María Allende, J.C. Meneu, Yilliam Fundora, Rafael San Juan, Manuel Lizasoaín, Estela Paz‐Artal, José María Aguado,

Patients with end-stage liver disease (ESLD) show a low absolute number of peripheral blood lymphocyte subpopulations (PBLSs). We investigated if the baseline PBLS could categorize orthotopic liver transplantation (OLT) recipients into groups at high or low risk for infection after transplantation. PBLSs were prospectively studied in 63 consecutive patients (42 males; mean age +/- standard deviation: 53.5 +/- 10.3 years) with ESLD prior to OLT. Thirty-five patients (55.6%) developed a total of 79 infectious ...

Tópico(s): Liver Diseases and Immunity

2009 - Lippincott Williams & Wilkins | Liver Transplantation

Jornais Acesso aberto

Barbara Hall, Jenny Woolf, Mike Graham, Philip Wearne, Paul Nelson, John Davison, Jon Swain, Mike Durham, Rob Hughes, John Peter, Sheila Stonham, Andrew Grice Political Correspondent, Tel Aviv, Susan d'Arcy, Alistair Scott, Liz Black, David Smith, Jane Goodall, William Green, Frederic Raphael, Mark Ellis, Edward Welsh, R. Buchanan-Dunlop, A F Lumley, Tony Allen-Mills, Patrick Stoddart, Susan Marling, Robert Sandall, Iain Johnstone, David Brierley, Irwin Stelzer, Mark Ottaway, Deryk Brown, Wendy Leigh, Richard Palmer Home Affairs Correspondent, La Paz, Maria Laura Avignolo, Hugh Canning, Margarette Driscoll, Arabella Fitzmaurice, David Cairns, Fiona Walsh Assistant City Editor, Frank Allaun President, Robert Harris, Caroline Lees, Flona Walsh, George Perry, Magdalena Buznea, Sue Mott, Mark Skipworth, Valerie Green, Bernard Cafferty, Stuart Wavell, Roger Eglin, Marie Colvin Middle East Correspondent, Paul Donovan, Janette Marshall, Ian Macwhinnie, Jeff Randall, Deirdre McQUILLAN, Rev John McKnight, S Keith, Walter Grey, Michael Durham, David Lawrenson, General De La Billiere, Douglas Farah, Charles Hymas Education Correspondent, Gareth David, Brian Reading, John Karter, Horton Northampton, Patrick Taylor-Martin, Marie Colvin, Diana Wright, Los Angeles, Stephen Jones, Ronald Hayman, Dr Karl Pagac President, R Johnson, Patricia Valentine, Martin Searby, Norman Stone, Malcolm Wlnton, Mitchell Symons, Aileen Ballantyne Medical Correspondent, Orna Mulcahy, Rebecca Fowler, Andrew Yates, David Hunn, James Blitz, Mihir Bose, Michael Austin, Paul Barker, Brian Glanville, Stan Levenson, Greta Scacchi, Norman Macrae, Chris Dighton, Helen Berg, Andrew Lorenz, Martin Anscombe Board Member National Chamber of Trade, Duncan Bryson, David Wickers, Sam Kiley, Tom Nairn, Chris Lightbown, Andrew Davidson, Paula Reed, Margaret Park, Neil MacLean, Anthony Howard, Peter Roebuck, Joanna Simon, James Dalrymple, Ron Suthers, David Ariev, Boris Schapiro,

Contents Secret Gulf papers stolen from car in security blunder Setback for Major as poll puts Labour in the lead Kuoni Contents Cold comfort: After the ...

1990 - Gale Group | Sunday Times HA GDA

Artigo Revisado por pares

Mariona Jové, José C. E. Serrano, Nàdia Ortega-Olivé, Victòria Ayala, Neus Anglès, Jordi Reguant, José Ramón Morelló, MaríaPaz Romero, MaríaJosé Motilva, Joan Prat, Reinald Pamplona, Manuel Portero‐Otín,

Metabonomics has recently been used to study the physiological response to a given nutritional intervention, but such studies have usually been restricted to changes in either plasma or urine. In the present study, we demonstrate that the use of LC-Q-TOF-based metabolome analyses (foodstuff, plasma, urine, and caecal content metabolomes) in mice offer higher order information, including intra- and intercompartment relationships. To illustrate this, we performed an intervention study with three different ...

Tópico(s): Ginseng Biological Effects and Applications

2011 - American Chemical Society | Journal of Proteome Research

Artigo Revisado por pares

José Ramón Morelló, MaríaPaz Romero, MaríaJosé Motilva,

Abstract The aim of this work was to determine the effect of the climatological conditions of the olive crop season on the composition of monovarietal virgin olive oils obtained from the Arbequina cultivar with special emphasis on the phenolic fraction, its percent distribution, and related oil quality parameters such as oxidative stability and bitter index. The main differences were due to freeze injuries caused by low temperatures in December 2001. The levels of chlorophylls and carotenoids in ...

Tópico(s): Essential Oils and Antimicrobial Activity

2006 - Wiley | Journal of the American Oil Chemists Society

Artigo Revisado por pares

José-Ramón Morelló, MaríaPaz Romero, MaríaJosé Motilva,

The purpose of the work was to investigate the effect of the maturation process of the olive fruit on the phenolic fraction of drupes and oils from Arbequina, Farga, and Morrut cultivars. The level in the phenolic content of olive drupes declines rapidly during the black maturation phase. A general decreasing trend was observed too in the phenolic content of olive oils during the ripening process in the three varieties studied. Important differences in the high-performance liquid chromatography ...

Tópico(s): Essential Oils and Antimicrobial Activity

2004 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Víctor Emanuel Pessoa Martins, Marlos Gomes Martins, José Maria Paz de Araújo, Luís Osvaldo Rodrigues Silva, Hamilton Antônio de Oliveira Monteiro, Francisco Corrêa Castro, Pedro Fernando da Costa Vasconcelos, Maria Izabel Florindo Guedes,

Pela primeira vez é registrada a ocorrência de Aedes (Stegomyia) albopictus em área urbana da cidade de Fortaleza, no Estado do Ceará, Brasil. De janeiro a julho de 2005 foram utilizadas ovitrampas para a coleta de ovos de Aedes spp., os quais foram mantidos em laboratório para desenvolvimento até a fase adulta. Os mosquitos resultantes foram identificados e submetidos a testes para o isolamento dos vírus da dengue. Foram identificados 13 espécimes de Aedes albopictus, todos fêmeas. Não foi isolado ...

Tópico(s): Insect Pest Control Strategies

2006 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública

Artigo Acesso aberto Revisado por pares

Yoana Nuevo Ordóñez, Marı́a Montes-Bayón, Elisa Blanco‐González, J. Paz-Jiménez, José María Tejerina-Lobo, José Miguel Peña-López, Alfredo Sanz‐Medel,

A study on the level of metals released to body fluids from patients carrying metal-on-metal (based on Co–Cr alloys) total hip prosthesis and titanium alloys dental implants has been conducted. In the first part, total elemental determination of Co, Cr, Ti, Mo and Mn was done in whole blood and urine for both, control individuals and hip arthroplasty patients. Additionally, the work was extended to patients who carried dental implants. The samples, either acid digested (blood) or just diluted (urine) ...

Tópico(s): Extraction and Separation Processes

2009 - Royal Society of Chemistry | Journal of Analytical Atomic Spectrometry

Artigo Revisado por pares

Paz Delgado, José María Ruiz Sánchez de León, Eduardo J. Pedrero Pérez,

Introduccion. Las quejas subjetivas de memoria constituyen uno de los motivos de consulta mas frecuentes a los servicios sanitarios, aunque apenas existen instrumentos validados en castellano para valorar su magnitud. Asi como los cuestionarios de quejas de memoria habitualmente incluyen items referentes a aspectos atencionales y ejecutivos, se formulan hipotesis acerca de su relacion con otros procesos dependientes de la integridad de la corteza prefrontal. Objetivo. Se trata de estudiar las propiedades ...

Tópico(s): Neural and Behavioral Psychology Studies

2012 - Viguera Publishers | Revista de Neurología

Artigo Revisado por pares

Mario Fernández‐Ruiz, Francisco López‐Medrano, Luís M. Allende, Amado Andrés, Ana García‐Reyne, Carlos Lumbreras, Rafael San Juan, J.M. Morales, Estela Paz‐Artal, José María Aguado,

Serial monitoring of peripheral blood lymphocyte subpopulations (PBLSs) counts might be useful in predicting post-transplant opportunistic infection (OI) after kidney transplantation (KT). PBLSs were prospectively measured in 304 KT recipients at baseline and post-transplant months 1 and 6. Areas under receiver operating characteristic curves were used to evaluate the accuracy of different subpopulations in predicting the occurrence of overall OI and, specifically, cytomegalovirus (CMV) disease. We ...

Tópico(s): Renal Transplantation Outcomes and Treatments

2014 - Springer Science+Business Media | Transplant International

Artigo Acesso aberto Revisado por pares

Mario Fernández‐Ruiz, Francisco López‐Medrano, P. Varela-Peña, J.M. Morales, Ana García‐Reyne, Rafael San Juan, Carlos Lumbreras, David Lora, Natalia Polanco, Amado Andrés, Estela Paz‐Artal, José María Aguado,

The usefulness of monitoring of complement levels in predicting the occurrence of infection in kidney transplant (KT) recipients remains largely unknown. We prospectively assessed serum complement levels (C3 and C4) at baseline and at months 1 and 6 in 270 patients undergoing KT. Adjusted hazard ratios (aHRs) for infection in each posttransplant period were estimated by Cox regression. The prevalence of C3 hypocomplementemia progressively decreased from 21.5% at baseline to 11.6% at month 6 (p = 0.017), ...

Tópico(s): Neurological Complications and Syndromes

2013 - Elsevier BV | American Journal of Transplantation

Artigo Acesso aberto Revisado por pares

Dorleta García, Raúl Prellezo, Paz Sampedro, José María Da Rocha, José Castro, Santiago Cerviño, Javier García-Cutrin, Marı́a-José Gutiérrez,

The landing obligation policy was one of the major innovations introduced in the last Common Fisheries Policy reform in Europe. It is foreseen that the policy will affect the use of fishing opportunities and hence the economic performance of the fleets. The problem with fishing opportunities could be solved if single-stock total allowable catches (TACs) could be achieved simultaneously for all the stocks. In this study, we evaluate the economic impact of the landing obligation policy on the Spanish ...

Tópico(s): Fish Ecology and Management Studies

2016 - Oxford University Press | ICES Journal of Marine Science

Artigo Acesso aberto Revisado por pares

Mario Fernández‐Ruiz, Patricia Almendro-Vázquez, Octavio Carretero, Tamara Ruiz‐Merlo, Rocío Laguna‐Goya, Rafael San Juan, Francisco López‐Medrano, Estéfani García‐Ríos, Vicente Más, Miguel Moreno-Batenero, Carmelo Loinaz, Amado Andrés, Pilar Pérez‐Romero, Estela Paz‐Artal, José María Aguado,

Severe acute respiratory syndrome coronavirus 2-specific cell-mediated immunity (SARS-CoV-2-CMI) elicited by mRNA-based vaccines in solid organ transplant (SOT) recipients and its correlation with antibody responses remain poorly characterized.We included 44 (28 kidney, 14 liver, and 2 double organ) recipients who received the full series of the mRNA-1273 vaccine. SARS-CoV-2-CMI was evaluated at baseline, before the second dose, and at 2 wk after completion of vaccination by an ELISpot-based interferon- ...

Tópico(s): Viral gastroenteritis research and epidemiology

2021 - Wolters Kluwer | Transplantation Direct

Artigo Revisado por pares

María‐Victoria Mateos, Albert Oriol, Joaquín Martínez‐López, Ma Teresa Cibeira, Raquel de Paz, María José Terol, José García‐Laraña, Enrique Garcíá Bengoechea, Rafael Martínez, Alejandro Martı́n, Felipe de Arriba, Luis Palomera, José‐Ángel Hernández‐Rivas, José-Luis Bello, Maria Luisa Martín, Yolanda González, Joan Bladé, Juan José Lahuerta, J.F. San Miguel,

Abstract Melphalan – Prednisone (MP) has been the Standard of care for elderly multiple myeloma patients in the past 40 years. However, bortezomib and thalidomide-based combinations have demonstrated to improve the efficacy in terms of both response rate and time to events as compared to MP. In two recent Phase II and phase III trials we have shown (Mateos et al. Blood 2006; San Miguel JF et al. EHA 2008) that the combination VMP is highly effective, but it remains to be elucidated which agent is the ...

Tópico(s): Peptidase Inhibition and Analysis

2008 - Elsevier BV | Blood

Errata Acesso aberto Brasil Produção Nacional Revisado por pares

Fábio Bastos Russomano, Bruno Reis Paz, Maria José de Camargo, Beatriz Gilda Jegerhorn Grinstejn, Ruth Khalili Friedman, Maria Aparecida Tristão, Caroline Alves de Oliveira,

In the article "Recurrence of cervical intraepithelial neoplasia in human immunodeficiency virus-infected women treated by means of electrosurgical excision of the transformation zone (LLETZ) in Rio de Janeiro, Brazil", published in the São Paulo Medical Journal, volume 131, issue number 6, 2013, the correct name of the fourth author is Beatriz Grinsztejn and not Beatriz Gilda Jegerhorn Grinstejn.

Tópico(s): Syphilis Diagnosis and Treatment

2013 - Medical Association of São Paulo | Sao Paulo Medical Journal

Artigo Revisado por pares

Luis Jiménez, Javier Ortiz-Tudela, Cástor Méndez Paz, María José Lorda,

Imitative behavior is known to be affected in Autism Spectrum Conditions. This issue has been addressed with a wide range of tasks and from many different perspectives. Here we use a version of Hamilton, Brindley, and Frith's (2007) bar-task in a sample of individuals with ASC and matched controls, to assess spontaneous imitation of goal-oriented actions. Contrary to previous studies which relied on ambiguous instructions to explore the spontaneous tendency to copy inefficient action patterns (Jiménez, ...

Tópico(s): Child and Animal Learning Development

2015 - Elsevier BV | Research in autism spectrum disorders

Revisão Acesso aberto Revisado por pares

Fátima Morales, Sergio Montserrat‐de la Paz, María José León, Fernando Rivero‐Pino,

Malnutrition refers to a person's status as under- or overnourished, and it is usually associated with an inflammation status, which can subsequently imply a different health status, as the risk of infection is increased, along with a deterioration of the immune system. Children's immune systems are generally more susceptible to problems than adults. In the situation of malnutrition, because malnourished children's immune systems are compromised, they are more likely to die. However, little is known ...

Tópico(s): Birth, Development, and Health

2023 - Multidisciplinary Digital Publishing Institute | Nutrients

Artigo Revisado por pares

José-Ramón Morelló, Satu Vuorela, MaríaPaz Romero, MaríaJosé Motilva, Marina Heinonen,

The aim of this study was to characterize antioxidant activities of phenolic compounds that appear in olive pulp and olive oils using both radical scavenging and antioxidant activity tests. Antiradical and antioxidant activities of olive pulp and olive oil phenolic compounds were due mainly to the presence of a 3,4-dihydroxy moiety linked to an aromatic ring, and the effect depended on the polarity of the phenolic compound. Glucosides and more complex phenolics exhibited higher antioxidant activities ...

Tópico(s): Free Radicals and Antioxidants

2005 - American Chemical Society | Journal of Agricultural and Food Chemistry

Carta Acesso aberto Revisado por pares

Mario Fernández‐Ruiz, Francisco López‐Medrano, Luís M. Allende, Amado Andrés, Estela Paz‐Artal, José María Aguado,

... López-Medrano1 Luis M. Allende2 Amado Andrés3 Estela Paz-Artal2 José María Aguado1 1 Unit of Infectious Diseases Instituto de ...

Tópico(s): Renal Transplantation Outcomes and Treatments

2014 - Wolters Kluwer | Transplantation

Carta Acesso aberto Revisado por pares

Mario Fernández‐Ruiz, Francisco López‐Medrano, Rafael San Juan, Luís M. Allende, Estela Paz‐Artal, José María Aguado,

Tópico(s): Cytomegalovirus and herpesvirus research

2015 - Oxford University Press | The Journal of Infectious Diseases

Artigo Revisado por pares

Luz S. Artajo, MaríaPaz Romero, José Ramón Morelló, MaríaJosé Motilva,

The study of the antioxidant effects of biophenolic compounds is supported by the current interest in natural products and the ongoing replacement of synthetic antioxidants by natural antioxidants from plant sources. Olives and olive oil, especially extra virgin olive oil, contain a variety of bioactive compounds (phytochemicals) widely considered to be potentially beneficial for health. This research was focused on evaluating the antioxidant activity of the enriched refined olive oil to discover ...

Tópico(s): Free Radicals and Antioxidants

2006 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Revisado por pares

Daniel Cacabelos, Victòria Ayala, Ana Belén Granado‐Serrano, Mariona Jové, Pascual Torres, Jordi Boada, Rosanna Cabré, Omar Ramírez‐Núñez, Hugo Gonzalo‐Benito, Aranzazu Soler-Cantero, José C. E. Serrano, Marı́a Josep Bellmunt, MaríaPaz Romero, MaríaJosé Motilva, Takashi Nonaka, Masato Hasegawa, Isidró Ferrer, Reinald Pamplona, Manuel Portero‐Otín,

Docosahexaenoic acid (DHA), a key lipid in nervous system homeostasis, is depleted in the spinal cord of sporadic amyotrophic lateral sclerosis (sALS) patients. However, the basis for such loss was unknown.DHA synthetic machinery was evaluated in spinal cord samples from ALS patients and controls by immunohistochemistry and western blot. Further, lipid composition was measured in organotypic spinal cord cultures by gas chromatography and liquid chromatography coupled to mass spectrometry. In these ...

Tópico(s): Neurogenetic and Muscular Disorders Research

2016 - Elsevier BV | Neurobiology of Disease

Artigo Revisado por pares

Víctor Asensi, Victoria Álvarez, Eulalia Valle-Garay, Álvaro Meana, Joshua Fierer, Eliécer Coto, J. A. Cartón, J. A. Maradona, José Paz, María Ángeles Diéguez, Belén de la Fuente, A. Moreno, Silvino Rubio, Maria José Tuya, Julián González Sarasúa, Sara Llames, J.M. Merino Arribas,

Abstract As osteomyelitis (OM) induces the synthesis of inflammatory cytokines and IL‐1 mediates bone resorption by osteoclasts we determined if there is an association between certain common polymorphisms of the genes encoding proinflammatory cytokines (IL‐1α and β, IL‐6, TNF‐α) and OM in adults. The IL‐1α (− 889) TT genotype was significantly more frequent among 52 OM patients than in 109 healthy controls (13/52, [25.0%] vs. 9/109, [8.3%], P = 0.0081, χ 2 = 7.01, OR = 3.7, 95% CI, 1.35–10.34). Patients who ...

Tópico(s): Immune Response and Inflammation

2003 - Wiley | American Journal of Medical Genetics Part A