From Peter Hazelhurst, By Michael Horsnell, , John Witherow, Richard Ford, By Clifford Webb Midlands Industrial Correspondent, By Frances Gibb, By George Clark Political Correspondent, From Robert Fisk, From Paul Routledge Labour Editor, By Fred Emery Political Editor, By a Staff Reporter, By Michael Baily Transport Correspondent, From Annabel Ferriman Health Services Correspondent, By Ian Bradley, By Edward Townsend, By Our Political Editor, From Our Correspondent, By John Roper, From Christopher Warman, By Hugh Clayton Agriculture Correspondent, By Nicholas Timmins, From Arthur Osman, By Henry Stanhope Defence Correspondent, By John Young Planning Reporter, From Our Education Correspondent, By Kenneth Gosling Arts Reporter, By Harry Golombek Chess Correspondent, By Pat Healy Social Services Correspondent, By Diana Geddes Education Correspondent, By Lucy Hodges, By Arthur Reed Air Correspondent, By Stanley Baldwin, From Patricia Clough, From David Wood, From Charles Hargrove, From Robert Schuil, From Patrick Brogan, By Hugh Noyes Parliamentary Correspondent, From Patrick Knight, by Arrigo Levi, From Christopher Walker, From Tewfik Mishlawi, From Michael Leapman, From Ivor Davis, From Hasan Akhtar, From Denis Reinhardt, Dessa Trevisan, From Richard Hughes, Michael Ratcliffe, Jacky Gillott, H. R. F. Keating, Michael Church, Ned Chaillet, Brian Martin, Nikolai Tolstoy, John Hackett, Jenny Woolf, Shona Crawford Poole, Hugh Clayton, John Higgins, John Percival, Joan Bakewell, Stanley Sadie, Barry Millington, Ronald Butt, Bernard Levin, Alan Hamilton, CARLOS BRAGA, , JOAOUIM JOSE, , BARBOSA ROMERO, , JULIO BARREIROS, MARTINS, , JOSE MANUEL VAZ, , CARLOS AUGUSTO, , G. MOURA BRANCO, , HERNANI LOPES, , da SILVA MALA, , L. CHAINHO, , PEREIRA, , L. de JESUS, SANTOS SOARES, , S. SANTOS, , JOAO PINHEIRO, , C. A. A. BERNARDO, , JOAO FERREIRA, , MARIA ISABEL, CALADO FERREIRA, , VIRGINIA M. GERGORIO, , EDITE M. G. P. FERNANDES, , JOSE MANUEL E. VALENCA, , MARIA RAQUEL VALENCA, , RAUL VIDAL, MARIO de ARAUJO, , REX DAVIS, , T. A. BIRRELL, , HUGH PESKETT, , W. E. BAUGH, , IAIN MONCREIFFE OF THAT ILK, , W. H. HANKIN, , ANTONY WHITAKER, , A. L. S. CORNER, , RICHARD RITGHIE, , TITO BENADY, , KENNET, , NOEL ANNAN, , MICHAEL HOLROYD, , DAVID GARNETT, , VICTOR PRITCHETT, , EVAN LUARD, , D. R. MIDGLEY, , ADRIAN C. BOULT, , GERTRUDE M. BANNISTER, , By the Staff of Nature, From Our Own Correspondent, By Geraldine Norman Sale Room Correspondent, By Clifford Longley Religious Affairs Correspondent, Cyril Bainbridge, By our Arts Reporter, W. W. W. and J. B. write:, Baroness Airey of Abingdon writes:, By Mitchell Platts, By Keith Macklin, By John Nicholls, John Young, From Richard Streeton, By John Woodcock Cricket Correspondent, By Michael Seely, By Norman Fox Football Correspondent, By Our Rifle Shooting Correspondent, By Pamela Macgregor-Morris, By John Watson, By Peter Hill Industrial Editor, By David Felton Labour Reporter, By Roman Eisenstein Banking Correspondent, By John Whitmore Financial Correspondent, By Tim Jones, From Michael Hornsby, By Peter Wilson-Smith, From Frank Vogl, William Olsen, By Kenneth Owen Technology Editor, By Bill Johnstone, By Margaret Stone, By Nicholas Hirst Energy Correspondent, MELVILLE BERNSTEIN, , MRS M. D. LOVEDAY, , JOHN GADD, , A. C. PARSONS, , J. B. DANEL, , HUGH CAWDRON, , BY THE FINANCIAL EDITOR, Ross Davies, David Blake, Derek Harris, Michael Prest Mining correspondent, By Our Financial Staff, By Rosemary Unsworth, Peter Davalle,
News: EEC budget is approved seven months late, Latest pamphlets Religious beliefs of Elgar, The Times Cook Separate ways with eggs, Kidnap victim is ...
1980 - Gale Group | TDA
Produção Nacional
Revisado por pares
Wolney de Andrade Martins, Evandro Tinoco Mesquita, Delma Maria da Cunha, Luiz Augusto de Freitas Pinheiro, Luiz José Martins Romêo Fo, Raul Carlos Pareto,
Anatomical and functional assessment of the heart through Doppler and echocardiography in patients with cell anemia (SCA).Twenty-five patients with SCA and ages ranging from 14 to 45 years were prospectively studied in a comparison with 25 healthy volunteers. All of them underwent clinical and laboratory evaluation and Doppler echocardiography as well. The measurements were converted into body surface indices.There were increases in all chamber diameters and left ventricle (LV) mass of the SCA patients. ...
Tópico(s): Acute Myocardial Infarction Research
1999 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Isabelle C. V. S. Martins, Natália Alvarenga Borges, Peter Stenvinkel, Bengt Lindholm, Hervé Rogez, Maria Conceição Nascimento Pinheiro, José Luíz Martins do Nascimento, Denise Mafra,
Tópico(s): Ginkgo biloba and Cashew Applications
2018 - Springer Science+Business Media | International Urology and Nephrology
Produção Nacional
Revisado por pares
Wolney de Andrade Martins, Evandro Tinoco Mesquita, Delma Maria da Cunha, Anelise Hagen Ferrari, Luiz Augusto de Freitas Pinheiro, Luiz José Martins Romêo Fo, Raul Carlos Pareto,
A anemia falciforme (AF) é uma hemoglobinopatia hereditária atribuída a uma lesão molecular específica, que é a troca do ácido glutâmico por valina no 6º resíduo da cadeia beta da hemoglobina 1 .Desta troca resulta a polimerização da hemoglobina em longas fibras formando um gel, o que torna a hemácia rígida e em forma de foice, diminuindo então sua flexibilidade e dificultando, conseqüentemente, sua passagem através da microcirculação 2 .Estudos de biologia molecular identificaram a origem africana ...
Tópico(s): Folate and B Vitamins Research
1998 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Produção Nacional
Revisado por pares
Liana Geraldo Souza de Oliveira, Daiany Alves Ribeiro, Manuele Eufrasio Saraiva, Delmácia Gonçalves de Macêdo, Julimery Gonçalves Ferreira Macedo, Patrícia Gonçalves Pinheiro, José Galberto Martins da Costa, Marta Maria de Almeida Souza, Irwin Rose Alencar de Menezes,
In most of the ethnobotanical studies among species with greater versatility, the Copaifera langsdorffii Desf. stands out due to the high number of therapeutic properties attributed to the oil-resin of its trunks. This species is widely distributed occurring both in preserved and anthropogenic environments. Plants that occur in different environmental conditions present qualitative and quantitative variation of the chemical constituents responsible for the biological activity, moreover, physiological ...
Tópico(s): Sesquiterpenes and Asteraceae Studies
2017 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Revisado por pares
María Elena Crespo-López, Gisele L. Macêdo, Gabriela de Paula Arrifano, Maria da Conceição Nascimento Pinheiro, José Luíz Martins do Nascimento, Anderson Manoel Herculano,
Mercury is an important source of environmental contamination affecting human beings throughout the world and especially in the Amazon. Riverside populations have been chronically exposed to relatively high levels of methylmercury for many years. Long-term effects of mercury exposure are not well known, but human genotoxicity was already showed in both in vitro and epidemiological studies. However, to date, only two studies were carried out in Amazonian populations with conflicting results and without ...
Tópico(s): Toxic Organic Pollutants Impact
2010 - Elsevier BV | Environment International
Produção Nacional
Maria da Conceição Nascimento Pinheiro, José Luíz Martins do Nascimento, Luiz Carlos L. Silveira, João Batista Teixeira da Rocha, Michael Aschner,
Mercury (Hg) toxicity is governed by cellular thiol compounds and its capacity to generate reactive oxygen radicals and oxidative stress. Selenium (Se) plays a key role in the prevention of the toxic effects of Hg by modulating the activity of several Se-dependent enzymes, including glutathione peroxidase (GSH-Px). In addition, dietary Se can reduce Hg toxicity by directly interacting with either Hg(II) or methylmercury (MeHg) to form inert products, such as HgSe complexes.. Although experimental and ...
Tópico(s): Heavy metals in environment
2009 - Taylor & Francis | Environmental Bioindicators
Produção Nacional
Revisado por pares
Larissa O. Paulista, Rui A.R. Boaventura, Vítor J.P. Vilar, Alexei Lorenzetti Novaes Pinheiro, Ramiro José Espinheira Martins,
Anaerobic digestion of crude glycerol from biodiesel production is a feasible way for methane production. However, crude glycerol (CG) contains impurities, such as long-chain fatty acids (LCFA) that can inhibit methanogenic microorganisms. Ultrasound promotes the hydrolysis of LCFA and deagglomerates the microorganisms in biological flocs. Furthermore, Aspergillus niger and Escherichia coli produce lipases capable of degrading LCFA. This study aims at improving the methane yield from anaerobic digestion ...
Tópico(s): Biofuel production and bioconversion
2019 - Springer Science+Business Media | Environmental Science and Pollution Research
João Pinheiro-Costa, José Mário Martins Costa, João Beato, Paulo Freitas‐da‐Costa, Elisete Brandão, Manuel Falcão, Fernando Falcão‐Reis, Ângela Carneiro,
<b><i>Purpose:</i></b> To report the clinical outcomes of intravitreal aflibercept therapy in eyes with refractory and recurrent neovascular age-related macular degeneration (AMD) switched from intravitreal bevacizumab or ranibizumab. <b><i>Methods:</i></b> This is a retrospective review of eyes with neovascular AMD switched to intravitreal aflibercept with at least 1 year of follow-up after the switch. All patients had had a minimum of 3 injections of ...
Tópico(s): Retinal Development and Disorders
2015 - Karger Publishers | Ophthalmologica
Produção Nacional
Revisado por pares
Onivaldo Bretan, Rafael Martins Pinheiro, José Eduardo Corrente,
Impaired balance is one of several factors that increase an elderly's susceptibility to falls. Balance assessment can be performed using postural tests and plantar cutaneous sensitivity tests.To assess balance disorders and loss of plantar cutaneous sensitivity in the elderly and look for association between these alterations.A descriptive cross-sectional study involving 45 elderly submitted to the Berg Balance Scale (BBS) and the plantar sensitivity test with nylon monofilament. We used chi-square ...
Tópico(s): Injury Epidemiology and Prevention
2010 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Produção Nacional
Revisado por pares
Delma Maria Cunha, Ademir Batista da Cunha, Wolney de Andrade Martins, Luís Augusto de Freitas Pinheiro, Luís José Martins Romêo, Álvaro V Moraes, Fernando Morcerf,
OBJECTIVE: To identiy left ventricular geometric patterns in hypertensive patients on echocardiography, and to correlate those patterns with casual blood pressure measurements and with the parameters obtained on a 24-hour ambulatory blood pressure monitoring. METHODS: We studied sixty hypertensive patients, grouped according to the Joint National Committee stages of hypertension.. Using the single- and two-dimensional Doppler Echocardiography, we analyzed the left ventricular mass and the geometric ...
Tópico(s): Heart Rate Variability and Autonomic Control
2001 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Karin Hardt, An Vandebosch, Jerald Sadoff, Mathieu Le Gars, Carla Truyers, D. Lowson, Ilse Van Dromme, Johan Vingerhoets, Tobias Kamphuis, Gert C. Scheper, Javier Ruiz‐Guiñazú, Saul N. Faust, Christoph D. Spinner, Hanneke Schuitemaker, Johan Van Hoof, Macaya Douoguih, Frank Struyf, Brian T. Garibaldi, Timothy E. Albertson, Christian Sandrock, Janet Lee, Mark R. Looney, Victor F. Tapson, Charles Shey Wiysonge, Luis Humberto Anaya Velarde, Daniel Backenroth, Jisha Bhushanan, Boerries Brandenburg, Vicky Cárdenas, Bohang Chen, Fei Chen, Polan Chetty, Pei-Ling Chu, Kimberly L. Cooper, Jerome Custers, Hilde Delanghe, A. Duca, Tracy Henrick, Jarek Juraszek, Catherine Nalpas, Monika Peeters, José Cirı́aco Pinheiro, Sanne Roels, Martin Ryser, José A. Salas, Samantha Santoro Matias, Ilse Scheys, Pallavi Shetty, Georgi Shukarev, Jeffrey J. Stoddard, Willem Talloen, NamPhuong Tran, Nathalie Vaissière, Elisabeth van Son-Palmen, Jiajun Xu, Erin Goecker, Alexander L. Greninger, Keith R. Jerome, Pavitra Roychoudhury, Simbarashe Takuva, J.L. Mendoza, Eric D. Achtyes, Habibul Ahsan, Azhar Alhatemi, Nancy A. Allen, José Ramón Arribas, Ghazaleh Bahrami, Lucía Bailón, Ali Ahsan Bajwa, Jonathan Baker, Mira Baron, Susana Benet, Driss Berdaï, Patrick Berger, Todd Bertoch, Claire Bethune, Sybille Bevilacqua, Maria Silvia Biagioni Santos, Ian Binnian, Karen Bisnauthsing, Jean‐Marc Boivin, Hilde Bollen, Sandrine Bonnet, Alberto M. Borobia, Élisabeth Botelho-Nevers, Phil Bright, Vianne Britten, Claire Brown, Amanda Buadi, Erik Buntinx, Lesley Burgess, Larry M. Bush, María Rosario Capeding, Quito Osuna Carr, Amparo Carrasco Mas, Hélène Catala, Katrina Cathie, T S Caudill, Fernando Cereto Castro, Kénora Chau, Steven Chavoustie, Marie Chowdhury, Nicolas Chronos, Paola Cicconi, Liliana Cifuentes, Sara Maria Cobo, Helen Collins, Hayley Colton, Carlos Rolando G. Cuaño, Valentino D’Onofrio, Paul I. Dargan, Thomas C. Darton, Peter Deane, José Luís del Pozo, Inge Derdelinckx, Amisha Desai, Michael Dever, Beatriz Díaz‐Pollán, Mark DiBuono, Matthew W. Doust, C.J. Duncan, José Maria Echave-Sustaeta, Frank Eder, Kimberly M. Ellis, Stanton R. Elzi, Stevan R. Emmett, Johannes Engelbrecht, Mim Evans, Theo Farah, Timothy Felton, João Pedro Ferreira, Catherine Floutier, Patrick A. Flume, Stacy Ford, Veronica G. Fragoso, Andrew Freedman, Emilia Frentiu, Chris Galloway, Florence Galtier, Julia Garcia Diaz, Irene García-García, Alcaide Garcia, Zoe Gardener, Pascale Gauteul, S Geller, Andrew Gibson, Claudia Gillet, Nicolas Girerd, Pierre‐Olivier Girodet, Maria Tarcela Gler, Richard Glover, Herschel Don D. Go, Karishma Gokani, Damien Gonthier, Christopher Green, Richard N. Greenberg, Carl J. Griffin, Coert Grobbelaar, Adonis Guancia, Gloria Hakkarainen, James B. Harris, Michael Hassman, Deirdre Heimer, Elizabeth Hellstrom-Louw, Yoan Herades, Christopher Holroyd, Nazreen Jeewa Hussen, Marie Grace Dawn Isidro, Yvonne Jackson, Manish Jain, Esaú João, Daniel Johnson, Ben Jones, Natasha Joseph, Analyn Jumeras, Patricia Junquera, Johanna Kellett‐Wright, Patrick Kennedy, Paul E. Kilgore, Kenneth Kim, Murray Kimmel, George Konis, Mark Kutner, Karine Lacombe, Odile Launay, Rajeka Lazarus, S. Lederman, Gigi Lefebvre, Katrina Lennon Collins, Isabel Leroux–Roels, Kenneth Wilson O. Lim, Muriel Lins, Edward Liu, Martin Llewelyn, Akbar Mahomed, Bernardo Maia, Alícia Marín-Candon, Xavier Martínez‐Gómez, Jean Benoît Martinot, Andrea Mazzella, Frank McCaughan, Louise McCormack, John McGettigan, Purvi Mehra, Rhonda Mejeur, Vicki Miller, Anthony Mills, Jose Molto Marhuenda, Prebashan Moodley, Marta Mora-Rillo, Beatriz Mothe, Daniel Mullan, Alasdair Munro, Paul J. Myers, Jeremy Nell, Tamara Newman Lobato Souza, Jane A. O’Halloran, Maria Dolores Ochoa Mazarro, Abigail Oliver, Jose Millan Onate Gutierrez, Jessica Ortega, Masaru Oshita, Susana Otero‐Romero, Jeffrey S. Overcash, DR Owens, Alice Packham, Mihaela Pacurar, Leonardo Paiva de Sousa, Adrian Palfreeman, Christian José Pallares, Rahul P. Patel, Suchet Patel, Leslie Pelkey, Denise Peluso, Florentina Penciu, Simmy Pinto, Kevin Pounds, Joe Pouzar, Antoinette Pragalos, Rachel M. Presti, Ashley Price, Ehsaan Qureshi, José Valdez Madruga, Mayur Ramesh, Bruce Rankin, Béatrice Razat, Breno Santos, Robert Riesenberg, Ernie Riffer, Siobhan Roche, Katie Rose, Pietro Rosellini, Patrick Rossignol, Beth Safirstein, Hernan Salazar, Gregorio Sánchez Vallejo, Smrithi Santhosh, Enrique Seco-Meseguer, Michael Seep, Emma Sherry, Philip Short, Patrick Soentjens, Joel Solis, Alejandro Soriano Viladomiu, Caroline Sorli, Selwyn Spangenthal, Niamh Spence, Elaine Stephenson, Cynthia Strout, Ronald Surowitz, Kristy Michelle Taladua, David Tellalian, Claire Thalamas, Nang Thiriphoo, Judith M. Thomas, Neal J. Thomas, Guillermo Trout, Mikel Urroz, Bernard Veekmans, Laurent Veekmans, Ralph Elvi Villalobos, Sarah Warren, Brian Webster, Alexander G. White, Gail Williams, Hayes Williams, Barbara A. Wilson, Alan Winston, Martin Wiselka, Marcus Zervos,
BackgroundDespite the availability of effective vaccines against COVID-19, booster vaccinations are needed to maintain vaccine-induced protection against variant strains and breakthrough infections. This study aimed to investigate the efficacy, safety, and immunogenicity of the Ad26.COV2.S vaccine (Janssen) as primary vaccination plus a booster dose.MethodsENSEMBLE2 is a randomised, double-blind, placebo-controlled, phase 3 trial including crossover vaccination after emergency authorisation of COVID- ...
Elsevier BV
Produção Nacional
Revisado por pares
Bruna Silva de Melo, Brenda Pinto de Morais, Vaniza Sheila de Souza Ferreira Sá, Filipe Dantas Lourinho, Ingrid Perpétuo Socorro Pinheiro Toda, José Luíz Martins do Nascimento, Dienifer Negrão Marques, Márcia Cristina Freitas da Silva, Giuliana Thaissa Modesto Cardoso, Luís André Luz Barbas, Marcelo Ferreira Torres, Nilton Akio Muto, Vanessa Jóia de Mello, Moisés Hamoy,
Nerium oleander Linn. is an Apocynaceae shrub which is among the most toxic ornamental plants. Although seizures are one of the symptoms associated with N. Oleander poisoning in humans, only a few studies are available on the behavioural and electrophysiological alterations caused by this plant poisoning. This study aimed at providing a thorough description of the electroencephalographic (EEG) and electromyographic (EMG) profiles throughout the experimental poisoning of Wistar rats (200–250 g) using ...
Tópico(s): Marine Toxins and Detection Methods
2020 - Elsevier BV | NeuroToxicology
Rui Pedro Gomes Pereira, Ana Cristina Pinheiro Guerra, Maria José Peixoto, Teresa Martins, Maria do Céu Barbieri‐Figueiredo, António Cândido Vaz Carneiro,
OBJECTIVES: to describe the process of translation and linguistic and cultural validation of the Evidence Based Practice Questionnaire for the Portuguese context: Questionário de Eficácia Clínica e Prática Baseada em Evidências (QECPBE). METHOD: a methodological and cross-sectional study was developed. The translation and back translation was performed according to traditional standards. Principal Components Analysis with orthogonal rotation according to the Varimax method was used to verify the ...
Tópico(s): Health Education and Validation
2015 - UNIVERSIDADE DE SÃO PAULO | Revista Latino-Americana de Enfermagem
Produção Nacional
Revisado por pares
José de Souza Filho, Elaine Yoshiko Matsubara, Leonardo Pereira Franchi, Igor Pinheiro Martins, Luis Miguel Ramires Rivera, José Maurício Rosolen, César Koppe Grisólia,
This is a detailed in vivo study of the biological response to carbon nanotubes network as probed by the zebrafish model. First, we prepared pristine carbon nanotubes (CNTs) by methanol chemical vapor deposition in the presence of Mn and Co as catalysts, followed by purification in acid, which furnished curved tubes with diameters lying between 10 and 130 nm. The CNT network consisted of pristine CNTs dispersed in water in the presence of a surfactant. The CNT network pellets corresponded to agglomerated ...
Tópico(s): Anesthesia and Neurotoxicity Research
2014 - Elsevier BV | Environmental Research
Produção Nacional
Revisado por pares
Eliene Lopes de Souza, Paulo Galvão, Cleane Do Socorro Da Silva Pinheiro, Marcus Paulus Martins Baessa, José Geilson Alves Demetrio, Wilker Roberto Rodrigues Brito,
Mapas geológicos e cartas estratigráficas das bacias sedimentares do Amazonas e do Solimões foram revisados, enfatizando-se as formações Alter do Chão, Içá e Solimões, detentoras das maiores reservas de água doce subterrânea, nessas bacias. A carência de informações sobre essas formações foi minimizada pela utilização de amostras de sondagens estratigráficas e de perfis construtivos, litológicos e geofísicos de poços de captação de água e de petróleo obtidos na Base Operacional Geólogo Pedro de ...
Tópico(s): Geological formations and processes
2013 - UNIVERSIDADE DE SÃO PAULO | Geologia USP Série Científica
Produção Nacional
Revisado por pares
Ulisses Rocha de Oliveira, Leonardo José Brandão Lima de Matos, Maria Cristiane Martins de Souza, Bruna Bandeira Pinheiro, José Cleiton Sousa dos Santos, Luciana Rocha Barros Gonçalves,
Tópico(s): Electrochemical sensors and biosensors
2018 - Springer Nature | Molecular Biology Reports
Produção Nacional
Revisado por pares
Ulisses Rocha de Oliveira, Leonardo José Brandão Lima de Matos, Maria Cristiane Martins de Souza, Bruna Bandeira Pinheiro, José Cleiton Sousa dos Santos, Luciana Rocha Barros Gonçalves,
Tópico(s): Analytical Chemistry and Chromatography
2017 - Springer Science+Business Media | Applied Biochemistry and Biotechnology
Produção Nacional
Revisado por pares
Leda R. C. Guimarães, Ana Paula Rodrigues, Patrícia Santana Barbosa Marinho, Adolfo H. Müller, Giselle Maria Skelding Pinheiro Guilhon, Lourivaldo da Silva Santos, José Luíz Martins do Nascimento, Edilene O. Silva,
Tópico(s): Toxin Mechanisms and Immunotoxins
2010 - Springer Science+Business Media | Parasitology Research
Produção Nacional
Revisado por pares
Lily Paola Martínez Abad, Caroline de Souza Almeida, Ana Márcia Menezes de Mattos, Ana Carolina P. Mendonça, Márcio José Martins Alves, Aimara Costa Pinheiro, Renato Porrozzi, Elfadil Abass, Ulrich Steinhoff, Henrique Couto Teixeira,
Canine visceral leishmaniasis (CVL) represents an important public health issue. Despite numerous diagnostic tests available, CVL diagnosis still needs to be improved to achieve a more accurate detection rate. Recently, rKLO8, a new antigenic protein of Sudanese Leishmania donovani, was studied for the first time in diagnosis of human visceral leishmaniasis (HVL) and showed good performance. The present study aimed to evaluate serum reactivity to rKL08 and the reference antigen rK26, and to compare ...
Tópico(s): Research on Leishmaniasis Studies
2016 - Elsevier BV | Acta Tropica
Produção Nacional
Revisado por pares
Francisca Idalina Neta, Amélia Carolina Lopes Fernandes, Adson José Martins Vale, Francisco Irochima Pinheiro, Ricardo Ney Cobucci, Eduardo Pereira de Azevedo, Fausto Pierdoná Gúzen,
SARS-CoV-2 infects host cells mainly through the interaction between the virus's Spike protein and the viral receptors namely Angiotensin-Converting Enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2). Both are highly expressed in the gastrointestinal tract, in the nasal and bronchial epithelium, as well as in the type II alveolar epithelial cells. The aim of this review is to report the evidences from the scientific literature on the pathophysiology and the available treatments for olfactory- ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2021 - Elsevier BV | Current Research in Pharmacology and Drug Discovery
Produção Nacional
Revisado por pares
Ivan Antônio Pinheiro, Luciano José Martins Vieira, Paulo César Motta,
Em que pesem as diferenças que os singularizam, os domínios da Literatura e da Gestão apresentam áreas em comum, possibilitando que a partir de uma, no caso a Literatura, se estude e amplie o conhecimento sobre a outra, a Administração. O presente artigo tem como objetivos realçar algumas das contribuições do mundo das artes para os estudos organizacionais e relatar e compartilhar com a comunidade acadêmica a experiência vivida, bem como tecer considerações críticas sobre o Projeto Literatura & Gestão. ...
Tópico(s): Business and Management Studies
2010 - UNIVERSIDADE FEDERAL DA BAHIA | Organizações & Sociedade
Ingo G. Reichenbach, Martin Bohley, Fábio José Pinheiro Sousa, Jan C. Aurich,
Nowadays, the prototypes of microfluidic systems are generally produced via micromilling of thermoplastic polymethyl methacrylate (PMMA). The main limitations are the design of micro tools with diameters D ≤ 50 μm adapted for each application, and the understanding of the machining process itself. The objective of this research work is to contribute to mastering the process of PMMA micromilling with tool diameters D ≤ 50 μm on a 3-axes precision milling machine. For this purpose, the process design must ...
Tópico(s): Advanced Surface Polishing Techniques
2018 - Springer Science+Business Media | The International Journal of Advanced Manufacturing Technology
... Giovanni Freitas Gomes André Zeni Salgado Antônio Carlos Pinheiro Oliveira Helton José Reis Universidade Federal de Minas Gerais, Belo Horizonte, Brazil Correspondence Gabriela Lopes Martins, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. ...
Tópico(s): Advanced MRI Techniques and Applications
2020 - Wiley | Alzheimer s & Dementia
José Lima Santos, Ana Martins Pinheiro, Ana Novais, Maria João Canadas,
The public-good nature of benefits of fuel management explains its current undersupply and the consequent wildfire blow. Policies to promote fuel management are thus required. To be cost-effective, they need to be informed by context-specific estimates of forest owners’ willingness-to-accept (WTA) for managing fuel. This study develops a choice-modeling approach to this problem. A survey of forest owners was undertaken in a wildfire-prone parish in Portugal. Respondents were asked about their willingness ...
Tópico(s): Conservation, Biodiversity, and Resource Management
2021 - Multidisciplinary Digital Publishing Institute | Forests
Margarida Simões, José Rino, Inês Pinheiro, Carlos Martins, Fernando Ferreira,
Viral interactions with host nucleus have been thoroughly studied, clarifying molecular mechanisms and providing new antiviral targets. Considering that African swine fever virus (ASFV) intranuclear phase of infection is poorly understood, viral interplay with subnuclear domains and chromatin architecture were addressed. Nuclear speckles, Cajal bodies, and promyelocytic leukaemia nuclear bodies (PML-NBs) were evaluated by immunofluorescence microscopy and Western blot. Further, efficient PML protein ...
Tópico(s): Herpesvirus Infections and Treatments
2015 - Multidisciplinary Digital Publishing Institute | Viruses
Produção Nacional
Revisado por pares
Adriana Guirado Artur, Jaciane Rosa Maria de Souza, Hermano Melo Queiroz, William Natale, José Israel Pinheiro, Thaís da Silva Martins, Carlos Alberto Kenji Taniguchi,
The association of mineral and organic fertilization is a nitrogen supply system for the melon crop. Nitrogen (N) fractionation is an important tool to understand its dynamics in the soil and the contribution of each fraction to N bioavailability. This study aimed to evaluate the effects of organic and mineral fertilization on organic and inorganic forms of soil N of the cultivation of yellow melon. The experiment was conducted in the Experimental Field of Pacajus, belonging to Embrapa Agroindústria ...
Tópico(s): Banana Cultivation and Research
2021 - Taylor & Francis | Communications in Soil Science and Plant Analysis
... org/10.1016/j.cbpb.2004.04.009Marcel José Martins dos Santos, Marcelo Antônio Amaro Pinheiro, , Ablação ocular no camarão Macrobrachium rosenbergii (De Man) ( ...
Tópico(s): Neurobiology and Insect Physiology Research
1968 - University of Chicago Press | Physiological Zoology
Produção Nacional
Revisado por pares
Rafael Pinheiro Amantéa, Mauri Fortes, José Helvecio Martins, Wanyr Romero Ferreira,
As a first objective, this study addresses a novel approach to drying efficiency analysis through transient models based on both the first and second laws of thermodynamics. As a second objective, we developed a numerical meshless scheme based on cubic radial basis functions to solve the associated nonlinear coupled advection-dominated set of partial differential equations. The simulated results showed excellent accuracy when compared with available literature data on drying. Finally, and most significantly, ...
Tópico(s): Heat Transfer Mechanisms
2013 - Taylor & Francis | Drying Technology
Produção Nacional
Revisado por pares
Wesley P. Calixto, A. Paulo Coimbra, Bernardo Pinheiro de Alvarenga, José Paulo Molin, Alexandre Cardoso, Luciano Martins Neto,
The purpose of this paper is to present an innovative methodology for 3-D soil stratification based on geoelectrical prospection. This methodology is useful in optimal substation grounding system designs by providing an accurate 3-D soil resistivity model. In the present methodology, the area being studied is subdivided into squared subareas and a recently developed geoelectrical prospection method based on the Wenner's method and on a genetic algorithm is applied to each subarea's edge. For each ...
Tópico(s): Electromagnetic Scattering and Analysis
2012 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Power Delivery