Produção Nacional
Revisado por pares
Denílson Campos de Albuquerque, Lineu José Miziara, José Francisco Kerr Saraiva, Ulisses S. Rodrigues, Artur Beltrame Ribeiro, Maurı́cio Wajngarten,
To evaluate the efficacy, safety and tolerability of sildenafil among Brazilian patients with hypertension treated with combinations of anti-hypertensive drugs.One hundred twenty hypertensive men aged 30 to 81 years old under treatment with 2 or more anti-hypertensive drugs and with erectile dysfunction (ED) lasting for at least 6 months were enrolled at 7 research centers in Brazil. Patients were randomized to receive treatment with either sildenafil or placebo taken 1 hour before sexual intercourse ( ...
Tópico(s): Migraine and Headache Studies
2005 - Sociedade Brasileira de Urologia | International braz j urol
Produção Nacional
Revisado por pares
Cláudio R. Reis-Filho, Elisângela R. Silva, Adalberto B. Martins, Fernanda F. Pessoa, Paula V.N. Gomes, Mariana Sponholz Araújo, Melissa Nunes Miziara, José Bento Alves,
In this study we investigated the possible use of human demineralised dentine matrix (DHDM), obtained from the extracted teeth, as bone graft material and evaluated the expression of vascular endothelial growth factor (VEGF) induced by this material in the healing process of tooth sockets of rats. To evaluate bone regeneration and expression of VEGF induced by DHDM, thirty-two male Wistar rats weighing approximately 200 g were used. After maxillary second molar extraction, the left sockets were filled ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2011 - Elsevier BV | Archives of Oral Biology
Produção Nacional
Revisado por pares
Luciana Marquez, Fernando Antônio Mauad de Abreu, Cynthia Lopes Ferreira, Guilherme Dias Alves, Melissa Nunes Miziara, José Bento Alves,
Considering the potential use of growth factors carried by liposomes for bone repair, this study aimed to assess the progress of bone healing process in injured alveoli of rats after administering EGF within liposomes. For this assessment we used 48 male Wistar rats that had their maxillary second molar extracted and separated into 5 groups: sockets filled with blood clot (BC), treated with empty liposome (L), PBS (P), EGF in PBS (EGF-P) and EGF in liposome (EGF-L). The animals were sacrificed after ...
Tópico(s): Orthopaedic implants and arthroplasty
2012 - Elsevier BV | Injury
Produção Nacional
Revisado por pares
Cynthia Lopes Ferreira, Fernando Antônio Mauad de Abreu, Gerluza Aparecida Borges Silva, Frank Ferreira Silveira, Luana Beatriz Araújo Barreto, Tony de Paiva Paulino, Melissa Nunes Miziara, José Bento Alves,
In this work we evaluated the bone-forming potential of BMP4, TGFβ1 and BMP4/TGFβ1 mixed by performing histological and morphometric analysis. We also evaluated the immunolabelling of fibronectin (FN) and collagen type III (Col III), two determinant proteins for the early phase of bone repair. Histological, histomorphometric and immunohistochemistry analysis were used to evaluate new bone and blood vessels formation as well as fibronectin and collagen type III expression. 112 male Wistar rats weighing ...
Tópico(s): Bone and Dental Protein Studies
2013 - Elsevier BV | Archives of Oral Biology
Produção Nacional
Revisado por pares
Lineu José Miziara, Marcelo E. Bigal, Carlos Alberto Bordini, José Geraldo Speciali,
Ao redor de 60% das mulheres com migrânea associam o período menstrual com a desencadear das crises. Para cefaléias não migranosas, essa relação é menos evidente. O objetivo desse estudo é apresentar a caracterização clínica da cefaléia menstrual. Cefaléia menstrual foi conceituada, em nosso estudo, como aquela cefaléia compreendida entre dois dias antes do primeiro dia da menstruação e o último dia da mesma. As variáveis avaliadas foram: intensidade, características e localização da dor e dos sintomas ...
Tópico(s): Breastfeeding Practices and Influences
2003 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
Luciana Baria Perdiz, Guilherme Henrique Campos Furtado, Marcelo Moura Linhares, Adriano Miziara Gonzalez, José Osmar Medina Pestana, Eduardo Alexandrino Medeiros,
A simultaneous pancreas-kidney transplantation (SPKT) is the best treatment option for type I diabetic patients with advanced chronic renal failure. Infectious complications affect 7-50% of the patients receiving this procedure. We conducted a nested case-control study to assess the risk factors for surgical site infection (SSI) in patients receiving SPKT at our centre between 2000 and 2006. Of the 119 evaluated transplant recipients, 55 (46.2%) developed SSIs and the 30 day mortality was 11.8%. Gram- ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2009 - Elsevier BV | Journal of Hospital Infection
Produção Nacional
Revisado por pares
Alcides Augusto Salzedas Netto, Alexandre Alberto Barros Duarte, Marcelo Moura Linhares, R. H. G. M. Mattar, Karina Lúcio Medeiros, Edson Khodor Cury, Gaspar de Jesus Lopes Filho, Adriano Miziara Gonzalez, José Luiz Martins,
Children with extrahepatic portal vein obstruction can be managed successfully by surgical intervention and should be evaluated for potential meso-Rex bypass. A Rex shunt variation is described to treat portal and superior mesenteric vein thrombosis. This technique uses the internal jugular vein as a conduit between the splenic vein and the left portal vein with splenic preservation.
Tópico(s): Gastroesophageal reflux and treatments
2011 - Elsevier BV | Journal of Pediatric Surgery
Produção Nacional
Revisado por pares
Giorgio V. Scagliotti, Silvia Novello, Joachim von Pawel, Martin Reck, José Rodrigues Pereira, Michael Thomas, José Elias Miziara, Beatrix Bálint, Filippo de Marinis, Alan Keller, Osvaldo Rudy Aren, Maria Csollak, István Albert, Carlos H. Barrios, Francesco Grossi, Maciej Krzakowski, Lisa Cupit, Frank Cihon, Sandra DiMatteo, Nasser H. Hanna,
PURPOSE This phase III, multicenter, randomized, placebo-controlled trial assessed the efficacy and safety of sorafenib, an oral multikinase inhibitor, in combination with carboplatin and paclitaxel in chemotherapy-naïve patients with unresectable stage IIIB or IV non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS Nine hundred twenty-six patients were randomly assigned to receive up to six 21-day cycles of carboplatin area under the curve 6 and paclitaxel 200 mg/m(2) (CP) on day 1, followed ...
Tópico(s): Cancer Genomics and Diagnostics
2010 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Giorgio V. Scagliotti, Maciej Krzakowski, Aleksandra Szczęsna, János Strausz, А. Н. Махсон, Martin Reck, Rafal Wierzbicki, István Albert, Michael Thomas, José Elias Miziara, Zsolt Pápai, Nina Karaseva, Sumitra Thongprasert, E. Dalmau, Joachim von Pawel, Ke Zhang, Paulina Selaru, L. Tye, Richard C. Chao, Ramaswamy Govindan,
Sunitinib plus erlotinib may enhance antitumor activity compared with either agent alone in non-small-cell lung cancer (NSCLC), based on the importance of the signaling pathways involved in tumor growth, angiogenesis, and metastasis. This phase III trial investigated overall survival (OS) for sunitinib plus erlotinib versus placebo plus erlotinib in patients with refractory NSCLC.Patients previously treated with one to two chemotherapy regimens (including one platinum-based regimen) for recurrent NSCLC, ...
Tópico(s): Colorectal Cancer Treatments and Studies
2012 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Produção Nacional
Revisado por pares
Adriane Feijó Evangelista, Maicon Fernando Zanon, Adriana Cruvinel Carloni, Flávia Escremim de Paula, Mariana Andozia Morini, Maressa Ferreira-Neto, Iberê Cauduro Soares, José Elias Miziara, Pedro De Marchi, Cristovam Scapulatempo‐Neto, Rui Manuel Reis,
ALK-rearranged lung cancers exhibit specific pathologic and clinical features and are responsive to anti-ALK therapies. Therefore, the detection of ALK-rearrangement is fundamental for personalized lung cancer therapy. Recently, new molecular techniques, such as NanoString nCounter, have been developed to detect ALK fusions with more accuracy and sensitivity.In the present study, we intended to validate a NanoString nCounter ALK-fusion panel in routine biopsies of FFPE lung cancer patients. A total ...
Tópico(s): Lung Cancer Research Studies
2017 - BioMed Central | BMC Pulmonary Medicine
Produção Nacional
Revisado por pares
Letícia Ferro Leal, Flávia Escremim de Paula, Pedro De Marchi, Luciano de Souza Viana, Gustavo Dix Junqueira Pinto, Carolina Dias Carlos, Gustavo Nóriz Berardinelli, José Elias Miziara, Carlos Maciel da Silva, Eduardo Caetano Albino da Silva, Rui Pereira, Marco Antônio de Oliveira, Cristovam Scapulatempo‐Neto, Rui Manuel Reis,
Abstract Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and smoking. The impact of EGFR and KRAS mutations in Brazilian lung cancer remains poorly explored. Thus, we investigated the frequency of EGFR and KRAS mutations in a large Brazilian series of lung adenocarcinoma together with patients’ genetic ancestry, clinicopathological and sociodemographic characteristics. The mutational frequency of ...
Tópico(s): Lung Cancer Research Studies
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Luis Paz‐Ares, J. Mezger, Tudor‐Eliade Ciuleanu, Jürgen R. Fischer, Joachim von Pawel, Mariano Provencio, Andrzej Każarnowicz, György Losonczy, Gilberto de Castro, Aleksandra Szczęsna, Lucio Crinó, Martin Reck, Rodryg Ramlau, Ernst Ulsperger, Christian Schumann, José Elias Miziara, Álvaro Edson Ramos Lessa, Mircea Dediu, Beatrix Bálint, H. Depenbrock, Victoria Soldatenkova, Raffael Kurek, Fred R. Hirsch, Nick Thatcher, Mark A. Socinski,
Summary Background Necitumumab is a second-generation recombinant human immunoglobulin G1 EGFR monoclonal antibody that competitively inhibits ligand binding. We aimed to compare necitumumab plus pemetrexed and cisplatin with pemetrexed and cisplatin alone in patients with previously untreated, stage IV, non-squamous non-small-cell lung cancer (NSCLC). Methods We did this randomised, open-label, controlled phase 3 study at 103 sites in 20 countries. Patients aged 18 years or older, with an Eastern Cooperative ...
Tópico(s): HER2/EGFR in Cancer Research
2015 - Elsevier BV | The Lancet Oncology
Produção Nacional
Revisado por pares
Juliana Muniz Miziara, Euclides Timóteo da Rocha, José Elias Miziara, Gustavo Fabene Garcia, Maria Izilda Previato Simões, Marco Antônio Borges Lopes, Lígia Maria Kerr, Carlos Alberto Buchpiguel,
The proper nodal staging of non-small cell lung cancer is important for choosing the best treatment modality. Although computed tomography remains the first-line imaging test for the primary staging of lung cancer, its limitations for mediastinum nodal staging are well known. The aim of this study is to evaluate the accuracy of hybrid single-photon emission computed tomography and computed tomography using 99mTc-sestamibi in the nodal staging of patients with non-small cell lung cancer and to identify ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2011 - Elsevier BV | Clinics
Produção Nacional
Revisado por pares
Lucas Gomes Patrocı́nio, Marcelo de Oliveira Rangel, Gustavo Sousa Marques Miziara, Alexandre Menezes Rodrigues, José Antônio Patrocı́nio, Tomás Patrocínio,
Postoperative pain is a serious problem, requiring an appropriate response from the medical doctor. In otolaryngology special attention is needed after uvulopala topharyngoplasty (UP3). Aim: To compare the efficacy of postoperative analgesia using ketorolac and ketoprofen after UP3. Patients and Methods: A prospective, randomized, double-blind study was made of 24 patients that were divided into 2 groups (14 received ketorolac and 10 received ketoprofen). Pain intensity was based on an analog visual ...
Tópico(s): Inflammatory mediators and NSAID effects
2007 - Elsevier BV | Brazilian Journal of Otorhinolaryngology
Produção Nacional
Revisado por pares
Fernando Antônio Mauad de Abreu, Cynthia Lopes Ferreira, Gerluza Aparecida Borges Silva, Camila de Oliveira Paulo, Melissa Nunes Miziara, Frank Ferreira Silveira, José Bento Alves,
This work evaluated the bone-forming potential of the platelet-derived growth factor isoform BB (PDGF-BB), insulin-like growth factor I (IGF-I), and mixed PDGF-BB/IGF-I delivered in liposomes compared with phosphate buffered saline (PBS), in the healing process of rat tooth sockets. One hundred and twelve Wistar rats were randomized into 7 groups of 16 animals each and were evaluated at 3, 7, 14 and 21 days after extraction of the maxillary second molars. The left sockets were treated with PBS (P), ...
Tópico(s): Bone and Dental Protein Studies
2013 - Fundação Odontológica de Ribeirão Preto | Brazilian Dental Journal
E. R. Lopes, E Chapadeiro, S. M. Batista, J.G. Saraiva da Cunha, Arthur Farias Rocha, Lineu José Miziara, João Ulisses Ribeiro, Renato J. Patto,
In an attempt to improve the post-mortem diagnosis of Chagas's disease, the authors performed haemagglutination tests (HAT), fluorescent Trypanosoma cruzi antibody tests (FAT), and complement fixation tests (CFT) on the pericardial fluid obtained at autopsy of 50 individuals with Chagas's heart disease, and 93 patients in whom this disease was not thought to be present. The results demonstrate that all three tests are efficient for the post-mortem diagnosis of Chagas's disease but suggest that their ...
Tópico(s): Viral Infections and Immunology Research
1978 - Oxford University Press | Transactions of the Royal Society of Tropical Medicine and Hygiene
M. O’Brien, Alan Sandler, Alexander Y. Popovich, Hristo Ganchev, Natalia Bogdanova, José Elias Miziara,
Tópico(s): Lung Cancer Research Studies
2005 - Elsevier BV | Lung Cancer
Produção Nacional
Revisado por pares
Rodrigo Sampaio Chiarantano, Fabiana de Lima Vazquez, Alexánder Franco, Larissa Cristina Ferreira, Maraisa Costa, Thais Talarico, Ângela Neves Oliveira, José Elias Miziara, Edmundo Carvalho Mauad, Eduardo Caetano da Silva, Luís Marcelo Ventura, Raphael Luiz Haikel, Letícia Ferro Leal, Rui Manuel Reis,
Lung cancer is the deadliest cancer worldwide and in Brazil. Despite strong evidence, lung cancer screening by low-dose computed tomography (LDCT) in high-risk individuals is far from a reality in many countries, particularly in Brazil. Brazil has a universal public health system marked with important inequalities. One affordable strategy to increase the coverage of resources is to use mobile units.To describe the implementation and results of an innovative lung cancer prevention program that integrates ...
Tópico(s): Lung Cancer Research Studies
2022 - SAGE Publishing | Cancer Control
Produção Nacional
Revisado por pares
Alcides Augusto Salzedas Netto, P.C.M. Silva, Fernando P. Vicentine, Fernanda Takamatsu, Adriano Miziara Gonzalez, José Ernesto Succi, J. L. Martins,
Congenital tracheobiliary fistula is an extremely rare malformation which involves an anomalous connection between respiratory and biliary trees. There are few cases described on literature, and so far at the moment there are 36 cases described. Patients usually show up with respiratory distress and bile stained expectoration. The diagnosis is made with images exams, like bronchoscopy, broncography, cholangiography, CT or MRI scan. The surgical approach must be as early as possible to prevent respiratory ...
Tópico(s): Biliary and Gastrointestinal Fistulas
2017 - Elsevier BV | Journal of Pediatric Surgery Case Reports
Produção Nacional
Revisado por pares
Érika Bevilaqua Rangel, João Roberto de Sá, Samirah Abreu Gomes, Aluízio Barbosa Carvalho, Cláudio S. Melaragno, Adriano Miziara Gonzalez, Marcelo Moura Linhares, José Osmar Medina Pestana,
Background Immunosuppressive regimen is associated with several metabolic adverse effects. Bone loss and fractures are frequent after transplantation and involve multifactorial mechanisms. Methods A retrospective analysis of 130 patients submitted to simultaneous pancreas-kidney transplantation (SPKT) and an identification of risk factors involved in de novo Charcot neuroarthropathy by multivariate analysis were used; P 78 mg/kg) and not adjusted to body weight were associated with Charcot neuroarthropathy ( ...
Tópico(s): Neurological and metabolic disorders
2012 - Wolters Kluwer | Transplantation
Produção Nacional
Revisado por pares
Alcides Augusto Salzedas Netto, E.S. Chinen, de Oliveira, Alberto Pasquetti, Ramiro Anthero de Azevedo, F.F. da Silva Patricio, Edson Khodor Cury, Adriano Miziara Gonzalez, Fernando P. Vicentine, José Luiz Martins,
Biliary atresia (BA) is the most common cause of liver transplantation in children. The earlier the treatment is done, the better the prognosis. The aim is to evaluate the impact of late diagnosis in children with BA, including the histopathological findings and success rate of biliary drainage in patients submitted to hepatic portoenterostomy (HPE).A retrospective study of cases of BA in the Department of Pediatric Surgery, Federal University of São Paulo (UNIFESP) between 1998-2011. We found 63 cases ...
Tópico(s): Congenital Anomalies and Fetal Surgery
2014 - Elsevier BV | Transplantation Proceedings
Produção Nacional
Revisado por pares
Mariana Gatto, Mariana Miziara de Abreu, Karen Ingrid Tasca, José Cláudio Simão, Carlos Magno Castelo Branco Fortaleza, Paulo Câmara Marques Pereira, Sueli Aparecida Calvi,
Introduction Visceral leishmaniasis (VL) is caused by the intracellular protozoan Leishmania donovani complex. VL may be asymptomatic or progressive and is characterized by fever, anemia, weight loss and the enlargement of the spleen and liver. The nutritional status of the patients with VL is a major determinant of the progression, severity and mortality of the disease, as it affects the clinical progression of the disease. Changes in lipoproteins and plasma proteins may have major impacts in the ...
Tópico(s): Viral gastroenteritis research and epidemiology
2013 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Rodrigo de Oliveira Cavagna, Icaro Alves Pinto, Flávia Escremim de Paula, Gustavo Nóriz Berardinelli, Débora Sant'Anna, Iara Viana Vidigal Santana, Vinícius Duval da Silva, Eduardo Caetano Albino da Silva, José Elias Miziara, Josiane Mourão Dias, Augusto Antoniazzi, Alexandre Arthur Jacinto, Pedro De Marchi, Miguel Ángel Molina‐Vila, Letícia Ferro Leal, Rui Manuel Reis,
TP53 is the most frequently mutated gene in lung tumors, but its prognostic role in admixed populations, such as Brazilians, remains unclear. In this study, we aimed to evaluate the frequency and clinicopathological impact of TP53 mutations in non-small cell lung cancer (NSCLC) patients in Brazil.We analyzed 446 NSCLC patients from Barretos Cancer Hospital. TP53 mutational status was evaluated through targeted next-generation sequencing (NGS) and the variants were biologically classified as disruptive/ ...
Tópico(s): Viral-associated cancers and disorders
2023 - Karger Publishers | Pathobiology
Produção Nacional
Revisado por pares
Rodrigo de Oliveira Cavagna, Flávia Escremim de Paula, Débora Sant'Anna, Iara Viana Vidigal Santana, Vinícius Duval da Silva, Eduardo Caetano Albino da Silva, Carlos E. Bacchi, José Elias Miziara, Josiane Mourão Dias, Pedro De Marchi, Letícia Ferro Leal, Rui Manuel Reis,
Recently, the agents AMG-510 (sotorasib, Amgen, Thousand Oaks, CA) and MRTX849 (adagrasib, Mirati Therapeutics, San Diego, CA) were developed to target the KRAS p.Gly12Cys mutation. 24,255][26] In a phase I study, 32.2% (19 out of 59) of sotorasib-treated patients presented with objective response, and 88.1% (52 out of 59) presented with the disease control. 26In a phase I and II study, 94% (17 out of 18) adagrasib-treated lung patients presented with disease control, and objective response was not yet ...
Tópico(s): Lung Cancer Research Studies
2021 - Lippincott Williams & Wilkins | JCO Global Oncology
Produção Nacional
Revisado por pares
Marina Baitello, Nelson Zocoler Galante, Luciano de Souza Coutinho, Érika Bevilaqua Rangel, Cláudio S. Melaragno, Adriano Miziara Gonzalez, José Medina‐Pestana,
OBJETIVO: O transplante pâncreas-rim é efetivo para pacientes com doença renal crônica terminal e diabetes mellitus insulino-dependente. A função retardada do enxerto pancreático é condição frequente exercendo impacto significativo nos resultados em curto prazo dos transplantes pâncreas-rim. O objetivo foi analisar o impacto da função retardada do enxerto pancreático no transplante pâncreas-rim. MÉTODOS: Análise retrospectiva de 180 receptores de transplante pâncreas-rim, incluindo dados demográficos ...
Tópico(s): Organ Donation and Transplantation
2011 - Sociedade Brasileira de Nefrologia | Brazilian Journal of Nephrology
Produção Nacional
Revisado por pares
Ricardo Alexandre Faria, Carlos Maciel da Silva, José Elias Miziara, Fernando Yaeda de Melo, Sandra Regina Morini da Silva, Cristiano Ribeiro Viana,
Relatamos o caso de uma paciente de 74 anos portadora de tumor de células gigantes em osso esterno. A apresentação clínica e radiológica indicava neoplasia primária de osso esterno. A paciente realizou exames complementares e cirurgia. O exame patológico confirmou o diagnóstico. Comumente observado em ossos longos no esqueleto apendicular, esse tipo de tumor caracteriza-se por sua agressividade local e pelo potencial metastático. Também fazemos uma revisão sobre o tema.
Tópico(s): Sarcoma Diagnosis and Treatment
2010 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Produção Nacional
Revisado por pares
Érika Bevilaqua Rangel, João Roberto de Sá, Cláudio S. Melaragno, Adriano Miziara Gonzalez, Marcelo Moura Linhares, Alcides Salzedas, José Osmar Medina Pestana,
Diabetes is a disease of increasing worldwide prevalence and is the main cause of chronic renal failure. Type 1 diabetic patients with chronic renal failure have the following therapy options: kidney transplant from a living donor, pancreas after kidney transplant, simultaneous pancreas-kidney transplant, or awaiting a deceased donor kidney transplant. For type 2 diabetic patients, only kidney transplant from deceased or living donors are recommended. Patient survival after kidney transplant has ...
Tópico(s): Diabetes and associated disorders
2009 - BioMed Central | Diabetology & Metabolic Syndrome
Andrea Miziara, José Antônio Marin‐Neto, Júlio Flávio Meirelles Marchini, Geraldo Figueiredo, Antônio O. Pintya, Marcus Vinı́cius Simões, Cleyde M. Antloga,
INTRODUÇÃO: A alteração regional da mobilidade segmentar do ventrículo esquerdo é marcador precoce de miocardiopatia chagásica crônica. Demonstramos recentemente que a discinergia em algumas regiões ventriculares pode ser revertida pela potenciação pós-extrassistólica. Apesar de angiografia coronária normal, pacientes com miocardiopatia chagásica apresentam falhas de perfusão, corroborando a hipótese de que a hibernação miocárdica pode ser responsável pelas anormalidades de mobilidade segmentar ...
Tópico(s): Cardiac Structural Anomalies and Repair
2009 - Elsevier BV | Revista Brasileira de Cardiologia Invasiva
Produção Nacional
Revisado por pares
Adriano Miziara Gonzalez, Gaspar de Jesus Lopes Filho, José Osmar Medina Pestana, Marcelo Moura Linhares, Maria Helena G. Silva, Rita Maria Aparecida Monteiro Moura, Cl udio Melaragno, Jo o Roberto de S, Erica Rangel, Tarcísio Triviño,
Belzer solution is considered to be the best preservation media used for pancreas transplantation; however, its high cost accounts for approximately 14.5% of all resources allocated by the Brazilian government toward each pancreatic transplant. The objective of the present study was to test a reduction of Belzer solution during pancreas harvest, thereby lowering procedural cost.The patients received pancreas-kidney transplantations during the period from January 2003 to August 2004. Patients were ...
Tópico(s): Organ Donation and Transplantation
2005 - Wolters Kluwer | Transplantation
E Herskovits, A. Famulari, Leopoldo Tamaroff, Adriano Miziara Gonzalez, A. Vázquez, R. Domı́nguez, H. Fraiman, José Henrique Andrade Vila,
A comparative study of the prevention of recurrences of cerebral transient ischemic attacks during a 6-month observation period was conducted in 73 patients treated with a combination of acetylsalicylic acid and dipyridamole (ASAD, 1,050 mg + 150 mg/day) and in 65 patients treated with pentoxifylline (PTX 1,200 mg/day, Trental® 400 t.d.s). The patients were randomly assigned to the treatments. Risk factor analysis showed high prevalence of arterial hypertension, hyperlipidemia and smoking in these patients. ...
Tópico(s): Neurological Disease Mechanisms and Treatments
1985 - Karger Publishers | European Neurology