Eleuterio Álvarez, Luz Candenas, Ricardo Pérez, José L. Ravelo, Julio D. Martı́n,
... Trans-Fused Polyether ToxinsEleuterio Alvarez, Maria-Luz Candenas, Ricardo Perez, Jose Luis Ravelo, and Julio Delgado MartinCite this: Chem. ...
Tópico(s): Dendrimers and Hyperbranched Polymers
1995 - American Chemical Society | Chemical Reviews
Eleuterio Álvarez, M. T. Fernández‐Díaz, Ricardo Pérez, José L. Ravelo, Alicia Regueiro, Jose A. Vera, Dácil Zurita, Julio D. Martı́n,
... Oxygen Bond-Forming CyclizationsEleuterio Alvarez, Maria T. Diaz, Ricardo Perez, Jose L. Ravelo, Alicia Regueiro, Jose A. Vera, Dacil ...
Tópico(s): Synthetic Organic Chemistry Methods
1994 - American Chemical Society | The Journal of Organic Chemistry
Carlos Montalbán, Víctor Abraira, Luca Arcaini, Eva Domingo‐Domènech, Pablo Guisado‐Vasco, Emilio Iannitto, Manuela Mollejo, Estella Matutes, Andrés J.M. Ferreri, Antonio Salar, Sara Rattotti, Andrea Carpaneto, Ricardo Pérez, José-Luis Bello, Miguel‐Teodoro Hernández, Dolores Caballero, Félix Carbonell, Miguel Á. Piris,
Splenic marginal zone lymphoma (SMZL) is a well- established type of indolent B-cell lymphoma [1] that usually involves the bone marrow, peripheral blood and spleen, and only rarely presents with n...
Tópico(s): Viral-associated cancers and disorders
2013 - Taylor & Francis | Leukemia & lymphoma/Leukemia and lymphoma
Elyse Swallow, Andrew Messali, Sameer R. Ghate, Evangeline McDonald, Emilie D. Duchesneau, José Ricardo Pérez,
When considering optimal second-line treatments for metastatic renal cell carcinoma (mRCC), clinicians and payers seek to understand the relative clinical benefits and costs of treatment.
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2018 - AMCP | Journal of Managed Care & Specialty Pharmacy
Sumanta K. Pal, Sameer R. Ghate, Nanxin Li, Elyse Swallow, Miranda Peeples, Miriam L. Zichlin, José Ricardo Pérez, Neeraj Agarwal, Nicholas J. Vogelzang,
BackgroundThe real-world survival outcomes and prognostic factors among patients receiving first-line targeted therapy for advanced renal cell carcinoma (aRCC) are not well known.Patients and MethodsAdult patients diagnosed with RCC and treated with first-line targeted therapy were identified from the Surveillance, Epidemiology, and End Results–Medicare database (January 1, 1993 to December 31, 2012). The patients were grouped into early (2006-2009) or late (2010-2012) targeted therapy era cohorts by ...
Tópico(s): Cancer Genomics and Diagnostics
2017 - Elsevier BV | Clinical Genitourinary Cancer
Anne Skalicky, Sameer R. Ghate, José Ricardo Pérez, Anne M. Rentz,
The objective of this research was to develop a disease-specific symptom inventory for soft tissue sarcoma.Literature review and clinical expert and patient interviews were conducted to determine disease-specific symptoms important to patients with one of the four STS subtypes. Clinical experts identified the most relevant STS symptom items from the item pool developed from literature review. Concept elicitation interviews were conducted with patients to elicit their STS symptom experiences followed ...
Tópico(s): Testicular diseases and treatments
2017 - Hindawi Publishing Corporation | Sarcoma
Nicholas J. Vogelzang, Sumanta K. Pal, Sameer R. Ghate, Elyse Swallow, Nanxin Li, Miranda Peeples, Miriam L. Zichlin, Mark K. Meiselbach, José Ricardo Pérez, Neeraj Agarwal,
Studies indicate similar survival and toxicity between pazopanib and sunitinib, but few have examined real-world outcomes among elderly patients with advanced renal cell carcinoma (RCC). The purpose of this retrospective claims analysis was to assess real-world overall survival (OS), healthcare resource utilization (HRU), and healthcare costs (both all-cause and associated with RCC diagnosis) among elderly advanced RCC patients starting pazopanib or sunitinib treatment.Advanced RCC patients aged 65 ...
Tópico(s): Renal and related cancers
2017 - Adis, Springer Healthcare | Advances in Therapy
Dimas Hernández, José Ricardo Pérez,
Abstract Background. Systemic chemotherapy is a treatment modality in the management of epidemic Kaposi's sarcoma (EKS). We conducted a prospective trial to compare bleomycin as a single agent with a regimen of low‐dose doxorubicin, bleomycin, and vincristine (ABV) in patients with advanced EKS. Methods. Twenty‐four homosexual or bisexual patients, between 21 and 40 years old, with positive enzyme‐linked Immunosorbent assay (ELISA) test for HIV and extensive EKS were included in the study. Half of ...
Tópico(s): Fungal Infections and Studies
1996 - Wiley | International Journal of Dermatology
Henry J. Henk, April Teitelbaum, José Ricardo Pérez, Satyin Kaura,
Zoledronic acid (ZOL), an intravenous bisphosphonate, has been shown to reduce and delay the incidence of skeletal-related events (SREs) in multiple myeloma (MM) patients with bone disease. A retrospective claims-based analysis was conducted that used two distinct US managed care databases to examine the relationship between persistency with ZOL and clinical benefit. Patients >18 years, diagnosed with MM, and with at least one claim for ZOL (or a claim for malignant bone disease and ZOL initiation within ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2012 - Wiley | American Journal of Hematology
Giorgio V. Scagliotti, P. Kosmidis, Filippo de Marinis, A. J. M. Schreurs, István Albert, Walburga Engel-Riedel, Denis Schallier, Santi Barbera, H.‐P. Kuo, V. Sallo, José Ricardo Pérez, C. Manegold,
BackgroundBone metastases are common in patients with advanced non-small-cell lung cancer (NSCLC) and can have devastating consequences. Preventing or delaying bone metastases may improve outcomes.Patients and methodsThis study evaluated whether zoledronic acid (ZOL) delayed disease progression or recurrence in patients with controlled stage IIIA/B NSCLC after first-line therapy. Patients received vitamin D and calcium supplementation and were randomized to i.v. ZOL (every 3–4 weeks) or no treatment ( ...
Tópico(s): Medical Imaging and Pathology Studies
2012 - Elsevier BV | Annals of Oncology
M. J. Durán-Avelar, Ricardo Pérez-Enríquez, José Francisco Zambrano‐Zaragoza, Leobardo Montoya‐Rodríguez, Ricardo Vázquez‐Juárez, Norberto Vibanco‐Pérez,
White spot disease (WSD) causes high mortality in cultured shrimp throughout the world. Its etiologic agent is the white spot syndrome virus (WSSV). The genomic repeat regions ORF 75, ORF 94, and ORF 125 have been used to classify WSSV isolates in epidemiological studies using PCR with specific primers and sequencing. The present study investigated the variation in nucleotide sequences from 107, 150, and 143 isolates of WSSV collected from Litopenaeus vannamei shrimp ponds with WSD outbreaks in northwestern ...
Tópico(s): Aquaculture disease management and microbiota
2015 - Inter-Research | Diseases of Aquatic Organisms
Humberto Lobato‐Morales, Alonso Corona‐Chávez, José‐Luis Olvera‐Cervantes, Ricardo A. Chavez‐Perez, José Luis Medina‐Monroy,
A wireless sensing system for the evaluation of the complex dielectric permittivity of solvent liquids is presented. Two sensing tags are proposed for testing of the samples. The first tag is based on a cavity resonator and the second makes use of the epsilon-near-zero effect. Both circuits are designed over the planar substrate-integrated-waveguide (SIW) technology, and operate at 4 GHz. A quartz capillary tube is used for the liquid measurements where only a small amount of sample volume is required. ...
Tópico(s): Microwave Engineering and Waveguides
2014 - IEEE Microwave Theory and Techniques Society | IEEE Transactions on Microwave Theory and Techniques
A. Astigarraga, Ana Oleaga, Ricardo Pérez‐Sánchez, JOSÉ. A. BARANDA, A. Encinas-Grandes,
We analysed in mice why the salivary gland extract (SGE‐2) from Ornithodoros erraticus and O. moubata induce a protective response with Freund's adjuvants (FAs) in swine while the saliva, in natural conditions, does not. Such protection has been ascribed to the fact that administration of SGE‐2 plus FAs permits the recognition of certain salivary components that under natural conditions are not immunogenic. The present findings confirm this hypothesis since in mice, which are unable to recognize the ...
Tópico(s): Aquaculture disease management and microbiota
1997 - Wiley | Parasite Immunology
Ricardo Pérez-Solís, José Juan Gervacio-Arciniega, Boby Joseph, M.E. Mendoza, Abel Moreno,
In this work, we report the synthesis of a monoclinic hydroxyapatite [Ca10(PO4)6(OH)2] (hereafter called HA) prepared by the sol-gel method assisted by ultrasound radiation at room temperature. The characterization of both the monoclinic and the hexagonal phases were performed by powder X-ray diffraction (PXRD) and using synchrotron radiation (SR). The measurement of the piezoelectricity was performed by piezoresponse force microscopy (PFM). The synthesis produced a mixture of monoclinic and hexagonal ...
Tópico(s): Luminescence Properties of Advanced Materials
2018 - Multidisciplinary Digital Publishing Institute | Crystals
Ricardo Pérez-Díaz, José Madrid‐Espinoza, Josselyn Salinas‐Cornejo, Enrique González-Villanueva, Simón Ruíz-Lara,
In plant cells, flavonoids are synthesized in the cytosol and then are transported and accumulated in the vacuole. Glutathione S-transferase-mediated transport has been proposed as a mechanism involved in flavonoid transport, however, whether binding of flavonoids to glutathione S-transferase (GST) or their transport is glutathione-dependent is not well understood. Glutathione S-transferases from Vitis vinífera (VviGSTs) have been associated with the transport of anthocyanins, however, their ability ...
Tópico(s): Horticultural and Viticultural Research
2016 - Frontiers Media | Frontiers in Plant Science
Ricardo Pérez‐Castillo, José A. Cruz-Lemus, Ignacio García Rodriguez de Guzmán, Mario Piattini,
Highlights? Business processes, most of which are automated by information systems, have become a key asset in organizations. ? During software modernization, ageing systems cannot be entirely discarded because they gradually embed meaningful business knowledge, which is not present in any other artifact. ? Recover business processes from legacy systems help to preserve the embedded business knowledge. ? A family of industrial case studies demonstrates that business process recovery is feasible in terms ...
Tópico(s): Software Engineering Research
2012 - Elsevier BV | Journal of Systems and Software
Carlos Montalbán, Víctor Abraira, Luca Arcaini, Eva Domingo‐Domènech, Pablo Guisado‐Vasco, Emilio Iannito, Manuela Mollejo, Estella Matutes, Andrés J.M. Ferreri, Antonio Salar, Sara Rattotti, Andrea Carpaneto, Ricardo Pérez Fernández, José Belló, Miguel‐Teodoro Hernández, Dolores Caballero, Félix Carbonell, Miguel Á. Piris,
Summary This international retrospective study of 593 S plenic M arginal Z one L ymphoma ( SMZL ) patients aimed to identify factors that determine treatment initiation and influence lymphoma‐specific survival ( LSS ). Logistic regression was used to identify the factors associated with treatment. A Cox regression was used to analyse LSS in a derivation cohort of 366 patients. This produced a prognostic index ( PI ) and enabled the identification of three risk groups. The resulting stratification was validated ...
Tópico(s): Viral-associated cancers and disorders
2012 - Wiley | British Journal of Haematology
Produção Nacional
Revisado por pares
André M. Faria, Ricardo Vessoni Perez, José Antônio Miguel Marcondes, Daniel Soares Freire, Roberto Blasbalg, José Maria Soares, Kleber Simões, Sylvia Asaka Yamashita Hayashida, Maria Adelaide A. Pereira,
Tópico(s): Reproductive Biology and Fertility
2011 - Nature Portfolio | Nature Reviews Endocrinology
Eduardo de la Torre-Escudero, Raúl Manzano-Román, Mar Siles‐Lucas, Ricardo Pérez‐Sánchez, Jose Carlos Moyano, Inmaculada Barrera, Ana Oleaga,
Tópico(s): Trace Elements in Health
2011 - Elsevier BV | Veterinary Parasitology
Ricardo José Comans-Pérez, José E. Sánchez, Laith Khalil Tawfeeq Al‐Ani, Manasés González‐Cortázar, Gloria Sarahi Castañeda-Ramírez, Pedro Mendoza de Gives, Alma Delia Sánchez-García, Jair Millán-Orozco, Liliana Aguilar-Marcelino,
This study evaluated in vitro the morphology of ten strains of edible mushroom: Pleurotus ostreatus (strains 1123 and 0152), P. eryngii (strains 1290 and 1291), P. cornucopiae (strains 1328 and 1330), Coprinus comatus (strain 1103), Panus sp. (strain 801), Lentinula edodes (strain 401) and L. boryanus (strain 402) on different growing media. In addition, the in vitro anthelmintic activity (AH) of the mycelium of the fungi against Haemonchus contortus infective larvae was evaluated in Petri dishes. Finally, ...
Tópico(s): Nematode management and characterization studies
2020 - Elsevier BV | Biological Control
Amit Mahajan, Omar Ibrahim, Ricardo José Bravo Pérez, Catherine L. Oberg, Adnan Majid, Erik Folch,
Central airway obstruction (CAO) is associated with significant morbidity and increased mortality. Bronchoscopic electrosurgical and laser ablative tools have proven to be safe and effective instruments for the treatment of malignant CAO. Although therapeutic modalities such as electrocautery, argon plasma coagulation, and laser have been used for decades, additional tools including radiofrequency ablation catheters continue to be developed for the treatment of CAO. These modalities are considered ...
Tópico(s): Esophageal and GI Pathology
2019 - Elsevier BV | CHEST Journal
Sumanta K. Pal, James Signorovitch, Nanxin Li, Miriam L. Zichlin, Zhimei Liu, Sameer R. Ghate, José Ricardo Pérez, Nicholas J. Vogelzang,
To assess real-world treatment patterns of targeted therapies after failure of first-line tyrosine kinase inhibitors in patients with advanced renal cell carcinoma.A large, retrospective review of medical charts of patients with advanced renal cell carcinoma in the USA was carried out. Descriptive statistics were used to summarize physicians' and patients' characteristics, treatment sequences, and reasons for treatment choices. P-values were calculated using χ2 -tests for categorical variables and ...
Tópico(s): Cancer Genomics and Diagnostics
2017 - Wiley | International Journal of Urology
Nicholas J. Vogelzang, Sumanta K. Pal, James Signorovitch, William M. Reichmann, Nanxin Li, Chelsey Yang, Zhimei Liu, José Ricardo Pérez, Eric Jonasch,
Background Second targeted therapies for metastatic renal cell carcinoma (mRCC) include mammalian target of rapamycin inhibitors (mTORis) and tyrosine kinase inhibitors (TKIs). This observational study compares overall survival (OS) and progression-free survival (PFS) of patients treated with everolimus (an mTORi) and axitinib (a TKI) following first TKI, and assesses the impact of type and duration of first TKI on the relative effectiveness of these second targeted therapies. Methods Retrospective reviews ...
Tópico(s): Cancer Genomics and Diagnostics
2016 - Taylor & Francis | Current Medical Research and Opinion
Rebecca Aft, Jose-Ricardo Perez, Noopur Raje, Vera Hirsh, Fred Saad,
Although dissemination may occur early in the course of many cancers, the development of overt metastases depends upon a variety of factors inherent to the cancer cells and the tissue(s) they colonize. The time lag between initial dissemination and established metastases could be several years, during which period the bone marrow may provide an unwitting sanctuary for disseminated tumor cells (DTCs). Survival in a dormant state within the bone marrow may help DTCs weather the effects of anticancer ...
Tópico(s): Medical Imaging and Pathology Studies
2011 - Elsevier BV | Critical Reviews in Oncology/Hematology
Santiago P. Aubourg, Ricardo I. Pérez‐Martín, Isabel Medina, José Manuel Gallardo,
... with acetaldehyde in a model systemSantiago P. Aubourg, Ricardo I. Perez-Martin, Isabel. Medina, and Jose M. GallardoCite this: J. Agric. Food Chem. 1992, ...
Tópico(s): Rabbits: Nutrition, Reproduction, Health
1992 - American Chemical Society | Journal of Agricultural and Food Chemistry
Zail Omán Rodríguez-Moré, Humberto Lobato‐Morales, Ricardo A. Chavez‐Perez, José Luis Medina‐Monroy,
An analysis of the complex dielectric permittivity of rum ʻHavana Club Añejo 3 Años' and its mixtures with methanol, ethanol, and deionized water is presented in this work. Measurements are carried out using the open-ended coaxial probe technique within a frequency range from 500 MHz to 15 GHz. Curves of the real and imaginary parts as well as the permittivity spectra (Cole–Cole diagram) and relaxation parameters of the liquids-under-test are presented. Distribution of the relaxation parameters for ...
Tópico(s): Acoustic Wave Phenomena Research
2018 - Taylor & Francis | Journal of Microwave Power and Electromagnetic Energy
María Blanco, Javier Fraguas, Cármen G. Sotelo, Ricardo I. Pérez‐Martín, José Antonio Vázquez,
This study illustrates the optimisation of the experimental conditions of three sequential steps for chondroitin sulphate (CS) recovery from three cartilaginous materials of Scyliorhinus canicula by-products. Optimum conditions of temperature and pH were first obtained for alcalase proteolysis of head cartilage (58 °C/pH 8.5/0.1% (v/w)/10 h of hydrolysis). Then, similar optimal conditions were observed for skeletons and fin materials. Enzymatic hydrolysates were subsequently treated with a combination ...
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2015 - Multidisciplinary Digital Publishing Institute | Marine Drugs
Carmen Piñeiro, Jorge Barros‐Velázquez, Ricardo I. Pérez‐Martín, José M. Gallardo,
The presence of specific enzymes in the sarcoplasmic protein fraction of eight gadoid fish species has been investigated following isoelectric focusing (IEF) in the 3.5–9.5 pH range. Lactate dehydrogenase (LDH) and glycerol-3-phosphate-dehydrogenase (G-3-PD) allowed the differentiation of most of the gadoids tested, even in the case of closely related species belonging to the genus Merluccius. Investigation of arginine kinase and creatine kinase afforded non-specific enzyme patterns in the species ...
Tópico(s): Aquaculture disease management and microbiota
2000 - Elsevier BV | Food Chemistry
Cármen G. Sotelo, Carmen Piñeiro, Ricardo I. Pérez‐Martín, José Manuel Gallardo,
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2000 - Springer Science+Business Media | European Food Research and Technology
Carmen Piñeiro, Jorge Barros‐Velázquez, Cármen G. Sotelo, Ricardo I. Pérez‐Martín, José M. Gallardo,
Eight gadoid fishesfive hakes (Merluccius spp.), cod (Gadus morhua), pollack (Pollachius pollachius), and blue whiting (Micromesistius poutassou)were characterized in their water-soluble protein profiles by two-dimensional (2D) electrophoresis both by nondenaturing isoelectric focusing (IEF) in the 4−6.5 pH range and gradient SDS−PAGE in the 12−14% range. Species-specific parvalbumin patterns (MW < 13 kDa, pI < 4.6) were observed in most of the species. 2D analysis of mixed extracts revealed that M. merluccius ...
Tópico(s): Meat and Animal Product Quality
1998 - American Chemical Society | Journal of Agricultural and Food Chemistry