Produção Nacional
Revisado por pares
Kátia Rocha, Luciana Salles, Francisco A. Alcaraz Garcia, Alberto Sardinha, José Paulo Teixeira,
Real estate investments in emerging economies are characterized by low liquidity, slow payback and high sunk costs; enduring uncertainties about demand, price/m2 and land costs. The introduction of the real options methodology in their analysis considers a housing development as an investment opportunity encompassing several options regarding information acquisition, deferral and abandonment. The model proposed values these managerial flexibilities and shows improved risk management, identifying ...
Tópico(s): Financial Reporting and Valuation Research
2007 - Elsevier BV | Emerging Markets Review
Produção Nacional
Revisado por pares
Suzana Matayoshi, Alfred Van Baak, Alexandra Lemos Cozac, Mariluze Sardinha, José Byron Vicente Dias Fernandes, Eurípedes da Mota Moura,
BACKGROUND After the advent of dacryocystorhinostomy (DCR), dacryocystectomy (DCT) was regarded as mutilant surgery and reserved for lacrimal sac tumors. PURPOSE To present current indications for dacryocystectomy. METHODS Eighteen eyes from 11 patients subjected to DCT were reviewed retrospectively. Nine patients had chronic dacryocystitis confirmed by dacryocystography and two patients had lacrimal sac tumors. RESULTS The indications for DCT were: three patients with systemic medical problems, three ...
Tópico(s): Ocular Surface and Contact Lens
2004 - Taylor & Francis | Orbit
César Agostinis‐Sobrinho, Carla Moreira, Sandra Abreu, Luís Lopes, Luís B. Sardinha, José Oliveira‐Santos, André Oliveira, Jorge Mota, Rute Santos,
This study aimed to evaluate the associations between muscular fitness and inflammatory biomarkers and to investigate the relationship between muscular fitness and selected clustered inflammatory biomarkers in adolescents. This is a cross‐sectional analysis with 529 adolescents (267 girls) aged 12‐18 years. Handgrip strength and standing long jump tests assessed MF . Continuous scores of clustered inflammatory biomarkers (sum of Z ‐scores of C‐reactive protein [ CRP ], C3, C4, fibrinogen, and leptin); metabolic ...
Tópico(s): Physical Activity and Health
2016 - Wiley | Scandinavian Journal of Medicine and Science in Sports
Produção Nacional
Revisado por pares
Venâncio Pereira Dantas Filho, Antônio Luís Eiras Falcão, Luis Antonio da Costa Sardinha, José Jorge Facure, Sebastião Araújo, Renato Giuseppe Giovanni Terzi,
A busca de fatores prognósticos para o traumatismo craniencefálico (TCE) tem sido alvo de muitos estudos nas últimas décadas. A identificação de indicadores consistentes da evolução destes pacientes tem representado um grande desafio e sua utilidade considerada evidente tanto para orientar o tratamento, quanto para a estimativa do resultado final. Baseados numa casuística de 206 pacientes com TCE grave (8 pontos ou menos pela Escala de Coma de Glasgow - ECG), estudamos a influência de vários fatores ...
Tópico(s): Trauma and Emergency Care Studies
2004 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Manuel Sardinha, José N. Canongia Lopes, Afonso Gusmão, L. Reis, Marco Leite,
Fused Filament Fabrication (FFF) applications are growing at an accelerated rate. As the impact of FFF in industries becomes more significant, accuracy and reliability of parts can compromise its adoption. Warping is a distortion where the surfaces of the printed part do not follow the intended shape of the design and is one of the most common problems when 3D printing with ABS material. In a previous work, ironing, a type of layer-by-layer heat treatment developed to reduce surface roughness, has ...
Tópico(s): Additive Manufacturing Materials and Processes
2022 - Elsevier BV | Procedia Structural Integrity
Nadja Apelt, Alda Pereira da Silva, Joana Ferreira, Irina Alho, Cristina P. Monteiro, Cláudia Marinho, Pedro J. Teixeira, Luís B. Sardinha, Maria José Laires, Mário Rui Mascarenhas, Manuel Bicho,
Erythrocyte acid phosphatase (ACP locus 1), also known as low-molecular-weight protein tyrosine phosphatase, has previously been associated to glycemia, dyslipidemia, and obesity. In this study, ACP1 genotype and activity were tested in 318 women aged 19 to 83 (mean, 51.74 +/- 13.44) years. ACP1 genotype was found to directly correlate to glutathione reductase activity (P < .001) and levels of low-density lipoprotein cholesterol (P = .038). Glutathione reductase activity was in turn found to correlate to a series ...
Tópico(s): Adipose Tissue and Metabolism
2009 - Elsevier BV | Metabolism
... Ascenção Rodrigues, Concha Rodríguez, Carlos Sáez, José Salgueiro, José-Alberto Sardinha, Julieta Silva, Dolors Sistac, José-Tomás Sousa and Acetre, Tecnosaga, Francesc Tomás, Fátima ...
Tópico(s): Musicology and Musical Analysis
2008 - Taylor & Francis | Ethnomusicology Forum
Diana A. Santos, Catarina N. Matias, Cristina P. Monteiro, Analiza M. Silva, Paulo Rocha, Cláudia S. Minderico, Luís B. Sardinha, Maria José Laires,
Magnesium plays significant roles in promoting strength. Surveys of athletes reveal that intake of magnesium is often below recommended levels. We aimed to understand the impact of magnesium intake on strength in elite male basketball, handball, and volleyball players. Energy and nutrient intake were assessed from seven-day diet record. Strength tests included maximal isometric trunk flexion, extension, and rotation, handgrip, squat and countermovement Abalakov jump, and maximal isokinetic knee ...
Tópico(s): Bone health and osteoporosis research
2011 - John Libbey Eurotext | Magnesium Research
Catarina N. Matias, Diana A. Santos, Cristina P. Monteiro, Ana Vasco, Fátima Baptista, Luís B. Sardinha, Maria José Laires, Analiza M. Silva,
Magnesium (Mg) deficiency has been associated with bone disorders. Physical activity is also crucial for bone mineralization. Bone mass loss has been observed to be accelerated in subjects with low Mg intake. We aim to understand if Mg intake mediates the association between bone mineral density (BMD) and lean soft tissue (LST) in elite swimmers. Seventeen elite swimmers (eight males; nine females) were evaluated. Bone mineral content, BMD, LST, and fat mass were assessed using dual energy X-ray absorptiometry. ...
Tópico(s): Parathyroid Disorders and Treatments
2012 - John Libbey Eurotext | Magnesium Research
Produção Nacional
Revisado por pares
Fernanda de Souza Nogueira Sardinha Mendes, José A. Pérez‐Molina, Andrea Angheben, Sheba Meymandi, Sergio Sosa‐Estáni, Israel Molina,
As a result of globalization and constant migratory flows, Chagas disease is now present in almost all continents. The management and treatment of the disease is often influenced by the economic and social context of the societies that host patients. In this manuscript, we aim to provide a comparative review of approaches to patients with Chagas disease in the Americas and Europe.
Tópico(s): Research on Leishmaniasis Studies
2022 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
... Oliveira Martins, Teixeira de Pascoaes, Fernando Pessoa, António Sardinha, Almada Negreiros, José Saramago, Eduardo Lourenço, Natália Correia and Miguel Torga.
Tópico(s): Linguistic and Sociocultural Studies
2014 - Intellect | International Journal of Iberian Studies
José P. Morgado, Catarina N. Matias, Cristina P. Monteiro, Francisco Alves, Joana F. Reis, Diana A. Santos, Analiza M. Silva, Fátima Martins, Maria Teresa Seixas, Petronila Rocha‐Pereira, Luís B. Sardinha, Maria José Laires,
There is general perception that elite athletes are highly susceptible to changes in immunohematological profile. The objective of this study was to compare immunohematological parameters of elite athletes of different aerobic and muscular strength sports and analyze changes over 2 months. Sixteen judoists and 14 swimmers were evaluated 2 months before (M1) and immediately prior to competition (M2). Hemogram and lymphocytes subpopulations were assessed with automatic counter and flow cytometry, respectively. ...
Tópico(s): Muscle metabolism and nutrition
2016 - NRC Research Press | Applied Physiology Nutrition and Metabolism
Produção Nacional
Revisado por pares
Venâncio Pereira Dantas Filho, Antônio Luís Eiras Falcão, Luis Antonio da Costa Sardinha, José Jorge Facure, Sebastião Araújo, Renato Giuseppe Giovanni Terzi,
The search for head injury prognostic factors has been intense in the last decades. The importance of identification of these factors has been also recognised to treatment orientation and results estimatives. Based on 206 severe head injuried patients series, we analyzed the influence of factors over the outcome. The initial severity by Glasgow coma scale, the presence of intracranial hypertension (over 20 mmHg), the type of intracranial lesion and the presence of hypoxia, systemic hypotension or ...
Tópico(s): Traumatic Brain Injury and Neurovascular Disturbances
2004 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
Gabriel Carreira Lencioni, Rafael Vieira de Sousa, Edson José de Souza Sardinha, Rodrigo Romero Corrêa, Adroaldo José Zanella,
The aim of this study was to develop and evaluate a machine vision algorithm to assess the pain level in horses, using an automatic computational classifier based on the Horse Grimace Scale (HGS) and trained by machine learning method. The use of the Horse Grimace Scale is dependent on a human observer, who most of the time does not have availability to evaluate the animal for long periods and must also be well trained in order to apply the evaluation system correctly. In addition, even with adequate ...
Tópico(s): Bee Products Chemical Analysis
2021 - Public Library of Science | PLoS ONE
José P. Sardinha, M.H. Gil, Josep V. Mercader, A. Montoya,
Azinphos-methyl (AM), O,O-dimethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate, is a dithiophosphorous insecticide extensively used for the control of fruit culture pests. In this work the ELIFA system, initially developed and marketed to substitute conventional ELISA methods, was used for the screening of supports and immunoreagents in the development of a flow immunosensor to AM. The objective was to find the optimal antibody concentration, support quantity and enzymatic tracer ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2002 - Elsevier BV | Journal of Immunological Methods
Produção Nacional
Revisado por pares
Karina R. B. Bastos, Renato Barboza, Luiz Roberto Sardinha, Momtchilo Russo, José María Álvarez, Maria Regina D’Império Lima,
Besides the established role of interleukin-12 (IL-12) and IL-18 on interferon-γ (IFN-γ) production by natural killer (NK), T, and B cells, the effects of these cytokines on macrophages are largely unknown. Here, we investigated the role of IL-12/IL-18 on nitric oxide (NO) and tumor necrosis factor-α (TNF-α) production by CD11b+ adherent peritoneal cells, focusing on the involvement of endogenously produced IFN-γ. C57BL/6 cells released substantial amounts of NO when stimulated with IFN-γ or lipopolysaccharide ( ...
Tópico(s): Immune Cell Function and Interaction
2007 - Mary Ann Liebert, Inc. | Journal of Interferon & Cytokine Research
Mădălina V. Natu, José P. Sardinha, Ilídio J. Correia, M.H. Gil,
Hydrogels and lyophilisates were obtained by chemical crosslinking of gelatin using N-hydroxysuccinimide and N, N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride. The systems were characterized with respect to the degree of crosslinking, morphology, water uptake, in vitro drug release and biocompatibility studies. Pilocarpine hydrochloride, a drug for the treatment of glaucoma, was loaded by soaking in an aqueous solution containing the drug. In vitro, the released drug percentage varied ...
Tópico(s): Hydrogels: synthesis, properties, applications
2007 - IOP Publishing | Biomedical Materials
Produção Nacional
Revisado por pares
Adele Schwartz Benzaken, Enrique Galbán García, José Carlos Sardinha, Valderiza Lourenço Pedrosa, Vera Paiva,
OBJETIVO: Descrever estudo de caso de intervenção de base comunitária, desenvolvido na perspectiva construcionista-emancipatória, para o controle das DST/Aids. MÉTODOS: Estudo descritivo desenvolvido no município de Manacapuru, Amazonas, de 1997-2004, sobre a utilização de procedimentos desenhados em colaboração com agentes governamentais, profissionais de saúde e comunidade. Foram levantados dados sobre a dinâmica da prostituição e a venda de preservativos na cidade, características comportamentais, ...
Tópico(s): HIV/AIDS Research and Interventions
2007 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Elsie Place, Luís Rojo, Eileen Gentleman, José P. Sardinha, Molly M. Stevens,
The development of bone replacement materials is an important healthcare objective due to the drawbacks of treating defects with bone autografts. In this work we propose a bone tissue engineering approach in which arginine-glycine-aspartic acid (RGD)-modified alginate hydrogels are crosslinked with bioactive strontium and zinc ions as well as calcium. Strontium was chosen for its ability to stimulate bone formation, and zinc is essential for alkaline phosphatase (ALP) activity. Calcium and strontium ...
Tópico(s): Bone Metabolism and Diseases
2011 - Mary Ann Liebert, Inc. | Tissue Engineering Part A
Erh-Hsuin Lim, José P. Sardinha, Simon Myers,
Cartilage has a limited regenerative capacity. Faced with the clinical challenge of reconstruction of cartilage defects, the field of cartilage engineering has evolved. This article reviews current concepts and strategies in cartilage engineering with an emphasis on the application of nanotechnology in the production of biomimetic cartilage regenerative scaffolds. The structural architecture and composition of the cartilage extracellular matrix and the evolution of tissue engineering concepts and ...
Tópico(s): Knee injuries and reconstruction techniques
2014 - Thieme Medical Publishers (Germany) | Archives of Plastic Surgery
Erh-Hsuin Lim, José P. Sardinha, Simon Myers, Molly M. Stevens,
Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed incorporating latent transforming growth factor-β1 (LTGF) into an electrospun poly(L-lactide) scaffold. Methods The electrospun scaffold was surface modified with NH3 plasma and biofunctionalised with LTGF to produce both random and orientated biofunctionalised ...
Tópico(s): Mesenchymal stem cell research
2013 - Thieme Medical Publishers (Germany) | Archives of Plastic Surgery
Tânia I. Pinto, José P. Coelho, Bruna I. Pires, Nuno R. Neng, J.M.F. Nogueira, João C. Bordado, José P. Sardinha,
Bran of different rice cultivars produced in Portugal were used to study supercritical carbon dioxide extraction conditions of rice bran oil (RBO) and evaluate and compare antioxidant activity and fatty acid composition of the different rice bran varieties. The effect of plant loading (10–20 g), CO2 flow rate (0.5–1.5 L/min), pressure (20–60 MPa), and temperature (40–80 °C) was studied. The amount of oil extracted ranged from 11.72%, for Ariete cultivar, to 15.60%, for Sirio cultivar. The main fatty acids ...
Tópico(s): Edible Oils Quality and Analysis
2021 - Multidisciplinary Digital Publishing Institute | Separations
Austine Ofondu Chinomso Iroegbu, Suprakas Sinha Ray, Vuyelwa Mbarane, João C. Bordado, José P. Sardinha,
Plastic pollution is a persistent challenge worldwide with the first reports evidencing its impact on the living and nonliving components of the environment dating back more than half a century. The rising concerns regarding the immediate and long-term consequences of plastic matter entrainment into foods and water cannot be overemphasized in light of our pursuit of sustainability (in terms of food, water, environment, and our health). Hence, some schools of thought recommend the revisitation and ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2021 - American Chemical Society | ACS Omega
Adele Schwartz Benzaken, Enrique Galbán García, José Carlos Sardinha, João Catarino Dutra, Rosanna W. Peeling,
Correct, early diagnosis and treatment of syphilis are essential for its control. Traditional diagnostic tests depend on specialized equipment, installations, and human resources. In the search for quick, simple tests, a project was conducted on the validation and reproducibility of four different tests, previously assessed by WHO reference laboratories. The study also verified the operational characteristics and acceptance by patients and health professionals. Samples obtained at an STD clinic ...
Tópico(s): HIV/AIDS Research and Interventions
2007 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Mauro Cunha Ramos, Maria Rita Castilhos Nicola, Natália Tenório Cavalcante Bezerra, José Carlos Sardinha, Júlia Sampaio de Souza Morais, Antônio Pedro Mendes Schettini,
Genital ulcers (GUs) represent a diagnostic challenge and can be secondary to neoplastic and inflammatory processes of different causes. Among those of infectious etiology, there are sexually transmitted infections (STIs), a very frequent reason for seeking the health service. The most common agents are herpes simplex virus and Treponema pallidum and, more rarely, Haemophilus ducreyi, Klebsiella granulomatis and Chlamydia trachomatis. A careful dermatological examination offers important diagnostic ...
Tópico(s): Reproductive tract infections research
2022 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
José Carlos Sardinha, Lívia Lima de Lima, Marcel Heibel, Antônio Pedro Mendes Schettini, Sinésio Talhari, Carolina Talhari,
Syphilis is one of the most common diseases that start with genital ulcers. Aside from the initial, classic ulcerative lesion of syphilis, called hard chancre, atypical presentations are common, with erosions, erythema, edema, balanitis, and other dermatological manifestations. Associated with initial genital lesions, the presence of inguinal adenopathies is frequent, and the presence of hardened and painless lymphangitis on the dorsum of the penis is rare.To describe atypical penile manifestations ...
Tópico(s): Body Image and Dysmorphia Studies
2020 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Regiane Aparecida Cavinato, Karina R. B. Bastos, Luiz Roberto Sardinha, Rosa Maria Elias, José María Álvarez, Maria Regina D’Império Lima,
The mechanisms by which antibodies interfere with Plasmodium growth are still under debate. Characterizing the asexual erythrocyte stages susceptible to antibodies from hyperimmune individuals is therefore a relevant contribution to vaccine research. In this study, using a virulent and synchronous murine malaria parasite, Plasmodium chabaudi chabaudi AJ, we have shown that trophozoites and circulating schizonts are not the main targets for antibodies from hyperimmune serum. In drug‐cured mice challenged ...
Tópico(s): Trypanosoma species research and implications
2001 - Wiley | Parasite Immunology
Produção Nacional
Revisado por pares
Jonas Rodrigues de Menezes Filho, José Carlos Sardinha, Enrique Galbán, Valéria Saraceni, Carolina Talhari,
Background: Urethral discharge syndrome (UDS) is characterized by the presence of purulent or mucopurulent urethral discharge.The main etiological agents of this syndrome are Neisseria gonorrhoeae and Chlamydia trachomatis. Objectives: To evaluate the effectiveness of the syndromic management to resolve symptoms in male urethral discharge syndrome cases in Manaus, Amazonas, Brazil. Methods: Retrospective cohort of male cases of urethral discharge syndrome observed at a clinic for sexually transmitted ...
Tópico(s): Syphilis Diagnosis and Treatment
2017 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Jose Dias Dias-Neto, Geovânio Milton Oliveira de, Geraldo Clelio Batista dos Santos,
A partir de 2001 ocorreu uma nova, lenta, mas continuada, recuperação da produção de sardinha-verdadeira (Sardinella brasiliensis), atingindo 83.920 t, em 2009. A queda de produção em 2010, da ordem de 30,59 %, em relação a 2009, indica a possibilidade de um novo ciclo de declínio, que pode levar a mais um grande colapso na pescaria de sardinha-verdadeira, se medidas urgentes não forem tomadas por parte dos gestores. A grande dinâmica de barcos permissionados, de ano para ano, pode apontar para um descontrole ...
Tópico(s): Aquaculture Nutrition and Growth
2011 - | Revista CEPSUL - Biodiversidade e Conservação Marinha
Produção Nacional
Revisado por pares
Renata Cassar, Fátima A. Sardinha, José Alfredo Gomes Arêas,
Summary Expanded products have been developed by extrusion of non‐conventional highly nutritious raw materials such as amaranth and chickpea blended with bovine lung. As sensory acceptance of these snacks is restricted, this study aimed at improving their texture, through the addition of monosodium glutamate (MSG) and disodium inosinate (IMP) flavor enhancers to the feeding material, or to the flavor added after the extrusion. Sensory and mechanical analyses showed that both enhancers affected texture, ...
Tópico(s): Sensory Analysis and Statistical Methods
2008 - Wiley | International Journal of Food Science & Technology