José G. Ramírez, R.J. Del Vecchio, José G. Ramírez,
Tópico(s): Engineering Education and Curriculum Development
1999 - Taylor & Francis | Technometrics
Produção Nacional
Revisado por pares
Norberto Garcia‐Cairasco, Miguel Moysés Neto, Flávio Del Vecchio, José Antônio Cortes de Oliveira, Francisco L. dos Santos, Olagide Wagner de Castro, Gabriel Maisonnave Arisi, Márcio Dantas, Ruither Oliveira Gomes Carolino, Joaquim Coutinho‐Netto, André Dagostin, M. Rodrigues, Ricardo M. Leão, Samir A. P. Quintiliano, Luiz F. Silva, Leonardo Gobbo‐Neto, Norberto Peporine Lopes,
Caramboxin: Patients suffering from chronic kidney disease are frequently intoxicated after ingesting star fruit. The main symptoms of this intoxication are named in the picture. Bioguided chemical procedures resulted in the discovery of caramboxin, which is a phenylalanine-like molecule that is responsible for intoxication. Functional experiments in vivo and in vitro point towards the glutamatergic ionotropic molecular actions of caramboxin, which explains its convulsant and neurodegenerative properties.
Tópico(s): Bioactive natural compounds
2013 - Wiley | Angewandte Chemie International Edition
Patrick B. Mark, Pantelis Sarafidis, Robert Ekart, Charles J. Ferro, Olga Balafa, Beatriz Fernández‐Fernández, William G. Herrington, Patrick Rossignol, Lucia Del Vecchio, José Manuel Valdivielso, Francesca Mallamaci, Alberto Ortíz, Ionuţ Nistor, Mario Cozzolino,
ABSTRACT Chronic kidney disease (CKD) is a major public health issue affecting an estimated 850 million people globally. The leading causes of CKD is diabetes and hypertension, which together account for >50% of patients with end-stage kidney disease. Progressive CKD leads to the requirement for kidney replacement therapy with transplantation or dialysis. In addition, CKD, is a risk factor for premature cardiovascular disease, particularly from structural heart disease and heart failure (HF). Until ...
Tópico(s): Pharmacology and Obesity Treatment
2023 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Norberto Garcia‐Cairasco, Miguel Moysés Neto, Flávio Del Vecchio, José Antônio Cortes de Oliveira, Francisco L. dos Santos, Olagide Wagner de Castro, Gabriel Maisonnave Arisi, Márcio Dantas, Ruither Oliveira Gomes Carolino, Joaquim Coutinho‐Netto, André Dagostin, Marcelo Cairrão Araújo Rodrigues, Ricardo M. Leão, Samir A. P. Quintiliano, Luiz F. Silva, Leonardo Gobbo‐Neto, Norberto Peporine Lopes,
Caramboxin: Bei Patienten mit chronischen Nierenkrankheiten treten nach dem Verzehr der Sternfrucht oft Vergiftungserscheinungen auf, deren Symptome im Bild genannt sind. Chemische Untersuchungen führten zur Entdeckung von Caramboxin, einem Phenylalanin-ähnlichen Molekül, das für die Vergiftung verantwortlich ist. Funktionale Experimente in vivo und in vitro weisen auf glutamaterge ionotrope molekulare Wirkungsweisen von Caramboxin hin, die zu konvulsiven und neurodegenerativen Eigenschaften führen.
Tópico(s): Alkaloids: synthesis and pharmacology
2013 - Wiley | Angewandte Chemie
C. Rivoisy, Antonio Vena, Laura Schaeffer, Caroline Charlier, Arnaud Fontanet, François Delahaye, Emilio Bouza, Olivier Lortholary, Patricia Muñóz, A. Lefort, Yazdan Yazdanpanah, Michel Wolff, Sandrine Houzé, Tristan Ferry, Martine Wallon, C. Strady, D. Toubas, Nicolas Bréchot, Benoît Henry, Arnaud Fekkar, Thierry Fourme, Isabelle Amouroux, Jean‐Luc Mainardi, Éric Dannaoui, O. Rogeaux, Marion Levast, Catherine Chirouze, L. MILLION, Frédéric Bastides, J. Chandenier, J P Lançon, Anne Ovize, P. Abgueguen, Jean-Philippe Bouchara, Laurent Tric, Gilbert Habib, Frederic Gourriet, Laurent Aaron, Osipova Yu.L., Marie‐Elisabeth Bougnoux, Fabrice Camou, Isabelle Accoceberry, Fernando Fernández Sánchez, Mariam Noureddine, Gabriel Rosas, Javier de la Torre, José I. Aramendi, Elena Bereciartúa, María Victoria Boado, Marta Campaña Lázaro, Josune Goikoetxea, J.J. Goiti, José L. Hernández, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Pedro María Pérez, Regino Rodríguez, Roberto Voces, Ma Victoria García López, Radka Ivanova Georgieva, Manuel Márquez, Isabel Rodríguez Bailón, Josefa Ruíz Morales, Ana María Cuende, Tomás Echeverría, Ana Fuerte, Eduardo Gaminde, Miguel Ángel Goenaga, Pedro Idígoras, José Antonio Iribarren, Alberto Izaguirre Yarza, Xabier Kortajarena Urkola, Carlos Reviejo, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Nemesio Álvarez, José María Bravo-Ferrer, Laura Castelo, José J. Cuenca‐Castillo, Pedro Llinares, Enrique Míguez Rey, María Rodríguez Mayo, Efrén Sánchez, Dolores Sousa Regueiro, F.J. Martínez-Moreno, M.M. Alonso, Beatriz Castro, Dácil García Marrero, Ma del Carmen Durán, Ma Antonia Miguel Gómez, Juan La Calzada, Ibrahim Nassar, Antonio Pláta Ciézar, José Ma Reguera Iglesias, Víctor Ortega Asensio, Clara V. Álvarez, Carlos Costas, Jesús de la Hera, Jonathan Fernández-Suárez, Lisardo Iglesias Fraile, Víctor León, José López Menéndez, Pilar Mencia-Bajo, Carlos Morales, Alfonso Moreno Torrico, Carmen Palomo, B. Martínez, Ángeles Rodríguez Esteban, Raquel Rodríguez-García, Mauricio Telenti Asensio, Manuel Almela, Yolanda Armero, Manuel Azqueta, Merçè Brunet, Ramón Cartañá, Carlos Cervera, Carlos Falces, Guillermina Fita, David Fuster, Cristina García de la Mària, José M. Gatell, Jaume Llopis Pérez, Francesc Marco, Carlos A. Mestres, José Ma Miró, Asunción Moreno, Salvador Pié i Ninot, Eduard Quintana, Carlos Paré, Juan M. Pericàs, José Luís Pomar, José Ramírez, Irene Rovira, Marta Sitges, Dolors Soy, Adrián Téllez, Jordi Vilà, Javier Bermejo, Eleonor Venegas B, Gregorio Cuerpo, Viviana de Egea, Alia Eworo, Ana Fernández‐Cruz, Ma Eugenia García Leoni, Marcela González del Vecchio, Víctor José González Ramallo, Martha Kestler Hernández, Mercedes Marín, Manuel Martínez‐Sellés, Ma Cruz Menárguez, Patricia Muñóz, Cristina Rincón, Hugo Rodríguez-Abella, Marta Rodríguez‐Créixems, Blanca Pinilla, Ángel Pinto, Maricela Valerio, Eduardo Verde Moreno, Isabel Antorrena, Belén Loeches, Mar Moreno, Ulises Ramírez, Verónica Rial Bastón, María Pilar Romero‐Gómez, Araceli Saldaña, Carlos Armiñanzas Castillo, Ana Arnáiz, José R. Berrazueta, Sara Bellisco, Manuel Cobo Belaustegui, Raquel Durán, MaCarmen Fariñas, Concepción Fariñas-Álvarez, Carlos Fernández Mazarrasa, Rubén Gómez Izquierdo, Claudia Gonzalez‐Rico, José Gutiérrez Díez, Rafael Martín Durán, Marcos Pajarón, José Antonio Parra, Ramón Teira, Jesús Zarauza, Pablo García Pavía, Jesús González, Beatriz Orden, António Ramos, Elena Rodríguez‐González, Tomasa Centella, José Manuel Hermida, José Luis Betrán Moya, Pilar Martín‐Dávila, Enrique Navas, Enrique Oliva, Alejandro del Río, Soledad Ruíz, Carmen Hidalgo Tenorio, Antonio de Castro, Marina de Cueto, Pastora Gallego, Juan Gálvez-Acebal, Jesús Rodríguez‐Baño, Arístides de Alarcón, Emilio García, Juan Luis Haro, José Antonio Lepe, Francisco López, Rafael Luque, Luis Javier Alonso, José Manuel Azcona, José Ramón Blanco, Lara García-Álvarez, José A. Oteo, Natividad Benito, Mercè Gurguí, Cristina Pacho, R. Pericás, Guillem Pons, Mar Álvarez, Ángel L. Fernández, AmparoMartínez, A. Prieto, Benito Regueiro, E. Tijeira, Marino Vega, Andrés Canut Blasco, José Cordo Mollar, Juan Carlos Gainzarain Arana, Oscar García Uriarte, Alejandro Martín López, Zuriñe Ortiz de Zárate, José Antonio Urturi Matos, Ma Belén Nacle, Antonio Sánchez-Porto, Luis Vallejo, José Ma Arribas-Leal, Elisa García Vázquez, Alicia Hernández Torres, Ana Lozano-Blázquez, Gonzalo de la Morena, Ángel Barajas, Javier Aramburu, Felicitas Elena Calvo, Anai Moreno Rodríguez, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, José Largo Pau, Ma Antonia Sepúlveda, Pilar Toledano Sierra, Sadaf Zafar Iqbal-Mirza, Eva Cascales Alcolea, Pilar Egea Serrano, Jose Roca,
Prosthetic valve endocarditis caused by Candida spp. (PVE-C) is rare and devastating, with international guidelines based on expert recommendations supporting the combination of surgery and subsequent azole treatment.We retrospectively analyzed PVE-C cases collected in Spain and France between 2001 and 2015, with a focus on management and outcome.Forty-six cases were followed up for a median of 9 months. Twenty-two patients (48%) had a history of endocarditis, 30 cases (65%) were nosocomial or healthcare ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2017 - Oxford University Press | Clinical Infectious Diseases
Josefa Ruiz‐Morales, Rada Ivanova–Georgieva, Núria Fernández-Hidalgo, Emilio García-Cabrera, José M. Miró, Patricia Muñóz, Benito Almirante, Antonio Pláta Ciézar, Víctor José González Ramallo, Juan Gálvez-Acebal, María Carmen Fariñas, José María Bravo-Ferrer, Miguel Á. Goenaga-Sánchez, Carmen Hidalgo-Tenorio, Josune Goikoetxea, A. de Alarcón-González, Fernando Fernández Sánchez, M. Noureddine, Gabriel Rosas, Javier de la Torre, José I. Aramendi, Elena Bereciartúa, María Victoria Boado, Marta Campaña Lázaro, J.J. Goiti, José L. Hernández, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Pedro María Pérez, Regino Rodríguez, Roberto Voces, Ma Victoria García López, Manuel Márquez, Isabel Rodríguez Bailón, Gemma Sánchez Espín, Juan C. Otero, Ana María Cuende, Eduardo Gaminde, Pedro Idígoras, José Antonio Iribarren, Alberto Izaguirre Yarza, Carlos Reviejo, Tomás Echeverría, Eduardo Gaminde, Ana María de Caso Fuertes, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Nemesio Álvarez, María del Mar Carmona, Laura Castelo, José Cuenca, Pedro Llinares, Enrique Míguez Rey, María Rodríguez Mayo, Dolores Sousa, Ma Carmen Zúñiga, Francisco Javier Martı́nez-Marcos, Joaquin Cabezas, M.M. Alonso, Beatriz Castro, Dácil García Marrero, Ma del Carmen Durán, Ma Antonia Miguel Gómez, Juan La Calzada, Ibrahim Nassar, José Ma Reguera Iglesias, Víctor Asensi, Carlos Costas, Jesús de la Hera, Jonathan Fernández-Suárez, José Manuel García Ruiz, Lisardo Iglesias Fraile, José López Menéndez, Pilar Mencía Bajo, Carlos Montilla, Alfonso Moreno Torrico, Carmen Palomo, B. Martínez, Ángeles Rodríguez, Raquel Rodríguez-García, Mauricio Telenti, Manuel Almela, Yolanda Armero, Manuel Azqueta, Ximena Castañeda, Carlos Cervera, Carlos Falces, C. García-de-la-Mària, José M. Gatell, Jaume Llopis, Francesc Marco, Carlos A. Mestres, Asunción Moreno, Salvador Pié i Ninot, J. M. Ramírez, Marta Sitges, Carlos Paré, Juan M. Pericàs, Javier Bermejo, Emilio Bouza, Viviana de Egea, Alia Eworo, Ana Fernández‐Cruz, Ma Eugenia García Leoni, Marcela González del Vecchio, Víctor José González Ramallo, Martha Kestler Hernández, Mercedes Marín, Manuel Martínez‐Sellés, Ma Cruz Menárguez, Hugo Rodríguez-Abella, Marta Rodríguez‐Créixems, J. Roda, Blanca Pinilla, Ángel Pinto, Maricela Valerio, Eduardo Verde Moreno, Isabel Antorrena, Mar Moreno, José Ramón Paño, Sandra Rosillo, María Romero, Araceli Saldaña, Carlos Armiñanzas Castillo, Ana Arnáiz, José R. Berrazueta, Sara Bellisco, Manuel Cobo Belaustegui, Raquel Durán, Concepción Fariñas-Álvarez, Carlos Fernández Mazarrasa, Rubén Gómez Izquierdo, Claudia Gonzalez‐Rico, José Gutiérrez Díez, Rafael Martín Durán, Marcos Pajarón, José Antonio Parra, Ramón Teira, Jesús Zarauza, Pablo García Pavía, Jesús Santos González, Beatriz Orden, António Ramos, Elena Rodríguez‐González, Tomasa Centella, José Ramón Fernández Hermida, José Luis Betrán Moya, Pilar Martínez, Enrique Navas, Enrique Oliva, Alejandro del Río, Soledad Ruíz, Antonio de Castro, Marina de Cueto, Pastora Gallego, Jesús Rodríguez‐Baño, José Antonio Lepe, Rafael Luque Márquez, Encarnación Gutiérrez‐Carretero, J Galan, Luis Javier Alonso, José Manuel Azcona, José Ramón Blanco, Lara García-Álvarez, José A. Oteo, Natividad Benito, Mercè Gurguí, Cristina Pacho, Roser Pericas, Guillem Pons, Mar Álvarez, Ángel L. Fernández, Amparo Martínez, A. Prieto, Benito Regueiro, E. Tijeira, Marino Vega, Andrés Canut Blasco, José Cordo Mollar, Juan Carlos Gainzarain Arana, Oscar García Uriarte, Alejandro Martín López, Zuriñe Ortiz de Zárate, José Antonio Urturi Matos, Ma Belén Nacle, Antonio Sánchez-Porto, Luis Vallejo, José María Arribas, Elisa García Vázquez, Alicia Hernández Torres, Joaquín Ruiz Gómez, Gonzalo de la Morena, Ángel Cabo Alonso, Javier Aramburu, Felicitas Elena Calvo, Anai Moreno Rodríguez, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, Ma Antonia Sepúlveda, Eva Cascales Alcolea, Pilar Egea Serrano, Jose Roca,
Summary Objective To evaluate the course of left-sided infective endocarditis (LsIE) in patients with liver cirrhosis (LC) analyzing its influence on mortality and the impact of surgery. Methods Prospective cohort study, conducted from 1984 to 2013 in 26 Spanish hospitals. Results A total of 3.136 patients with LsIE were enrolled and 308 had LC: 151 Child–Pugh A, 103 B, 34 C and 20 were excluded because of unknown stage. Mortality was significantly higher in the patients with LsIE and LC (42.5% vs. 28.4%; ...
Tópico(s): Ultrasound in Clinical Applications
2015 - Elsevier BV | Journal of Infection
Produção Nacional
Revisado por pares
Minelle E. Silva, Bruno S. Silvestre, Roselene C. Del Vecchio Ponte, José Ednilson Oliveira Cabral,
Amidst the high number of frameworks associated with supply chain sustainability (SCS), proper consideration to the role and importance of micro and small enterprises (MSEs) has been missing in the literature. To address this research gap, this paper investigates the driving factors that support MSE supply chains to achieve sustainability. We employ institutional and complexity theories to broaden our understanding of the dynamics behind neglected supply chain structures, especially the ones predominantly ...
Tópico(s): Supply Chain Resilience and Risk Management
2021 - Elsevier BV | Journal of Cleaner Production
Produção Nacional
Revisado por pares
Isabel M. Quadros, Maria Lúcia Oliveira de Souza Formigoni, Raquel Vecchio Fornari, José N. Nóbrega, Maria Gabriela Menezes Oliveira,
Behavioral sensitization to drugs of abuse seems to involve learning processes. In mice, ethanol-induced locomotor sensitization is potentiated by repeated pairing of ethanol (EtOH) injections and the testing chamber. The present study aimed to test: (1). the association between the performance in a contextual conditioning task and the development of behavioral sensitization to EtOH in mice; (2). whether EtOH sensitization would be expressed in a different testing environment. Male albino Swiss mice ( ...
Tópico(s): Memory and Neural Mechanisms
2003 - Lippincott Williams & Wilkins | Behavioural Pharmacology
Alejandro Llanes, Carlos M. Restrepo, Gina Del Vecchio, Franklin José Anguizola, Ricardo Lleonart,
Abstract Kinetoplastid parasites of the Leishmania genus cause several forms of leishmaniasis. Leishmania species pathogenic to human are separated into two subgenera, Leishmania ( Leishmania ) and L. ( Viannia ). Species from the Viannia subgenus cause predominantly cutaneous leishmaniasis in Central and South America, occasionally leading to more severe clinical presentations. Although the genomes of several species of Leishmania have been sequenced to date, only one belongs to this rather different subgenus. ...
Tópico(s): Parasites and Host Interactions
2015 - Nature Portfolio | Scientific Reports
Roger M. Enoka, Jacques Duchateau,
... during a mechanically constrained taskSimon Avrillon, Alessandro Del Vecchio, Dario Farina, José L. Pons, Clément Vogel, Jun Umehara, and François ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2015 - American Physiological Society | Journal of Applied Physiology
Produção Nacional
Revisado por pares
Bianca Miarka, Víctor Silveira Coswig, Fabrício Boscolo Del Vecchio, Ciro José Brito, John Amtmann,
This study aimed to compare time-motion analysis between weight divisions in male fighters and rounds of Mixed Martial Arts (MMA). The sample consisted of 2097 bouts separated by weight divisions (Flyweight n=114, Bantamweight n=224, Featherweight n=286, Lightweight n=450, Welterweight n=390, Middleweight n=316, Light heavyweight n=167, Heavyweight n=150) of 2012-2014 UFC™ events. The time-motion variables were categorized into low or high-intensity, stand-up or groundwork situations by round. Effects ...
Tópico(s): Sports injuries and prevention
2015 - Taylor & Francis | International Journal of Performance Analysis in Sport
Produção Nacional
Revisado por pares
Cristiane Queixa Tilelli, Flávio Del Vecchio, Artur José de Brum Fernandes, Norberto Garcia‐Cairasco,
We investigated a possible correlation between behavior during status epilepticus (SE) and underlying brain damage. Adult rats were electrically stimulated in the left amygdala to induce SE, which was stopped 2 hours later. We observed two different types of SE: (1) typical SE (TSE), with facial automatisms, neck and forelimb myoclonus, rearing and falling, and tonic–clonic seizures; (2) ambulatory SE (ASE), with facial automatisms, neck myoclonus, and concomitant ambulatory behavior. TSE was behaviorally ...
Tópico(s): Memory and Neural Mechanisms
2005 - Elsevier BV | Epilepsy & Behavior
Carlos Henríquez Miranda, José Francisco Del Vecchio, Fabián José Paternina,
La computación en la nube es el modelo que permite el acceso a una red bajo demanda de un conjunto de servicios informáticos configurables tales como infraestructura, aplicaciones y almacenamiento. En los últimos años este modelo ha permitido a las empresas tener presencia en la Web o simplemente adquirirservicios informáticos a un precio razonable sin necesidad de invertir en la compra de equipos físicos y lógicos. Este artículo presenta una visión general de los conceptos más importantes de la ...
Tópico(s): Big Data and Business Intelligence
2015 - Editorial Uniautonoma | Prospectiva
Melania Manco, José Manuel Fernández‐Real, Fabio Maria Vecchio, Valerio Gaetano Vellone, José María Moreno‐Navarrete, Vincenzo Tondolo, GianFranco Bottazzo, G Nanni, Geltrude Mingrone,
Tópico(s): Neuropeptides and Animal Physiology
2010 - Springer Science+Business Media | Obesity Surgery
Produção Nacional
Revisado por pares
Antoine Fouquet, Killian Leblanc, Marlene Framit, Alexandre Réjaud, Miguel Tréfaut Rodrigues, Santiago Castroviejo‐Fisher, Pedro L. V. Peloso, Ivan Prates, Sophie Manzi, Uxue Suescun, Sabrina Baroni, Leandro João Carneiro de Lima Moraes, Renato Sousa Recoder, Sergio Marques de Souza, Francisco Dal Vecchio, Agustín Camacho, José Mário Ghellere, Fernando J. M. Rojas‐Runjaic, Giussepe Gagliardi‐Urrutia, Vinícius Tadeu de Carvalho, Marcelo Gordo, Marcelo Menin, Philippe J. R. Kok, Tomas Hrbek, Fernanda P. Werneck, Andrew J. Crawford, Santiago R. Ron, Jonh Jairo Mueses-Cisneros, Rommel R. Rojas, Dante Pavan, Pedro Ivo Simões, Raffael Ernst, Anne‐Claire Fabre,
Abstract The outstanding biodiversity of the Guiana Shield has raised many questions about its origins and evolution. Frogs of the genera Adelastes, Otophryne and Synapturanus form an ancient lineage distributed mostly across this region. These genera display strikingly disparate morphologies and life-history traits. Notably, Synapturanus is conspicuously adapted to fossoriality and is the only genus within this group to have dispersed further into Amazonia. Moreover, morphological differences among ...
Tópico(s): Lepidoptera: Biology and Taxonomy
2020 - Oxford University Press | Biological Journal of the Linnean Society
Simon Avrillon, Alessandro Del Vecchio, Dario Farina, José L. Pons, Clément Vogel, Jun Umehara, François Hug,
We observed that the distribution of the strength of neural drive between the vastus lateralis and vastus medialis during a single-joint isometric task varied across participants. Also, we observed that the proportion of neural drive that was shared within and between these muscles also varied across participants. These results provide evidence that the neural strategies to control the vastus lateralis and vastus medialis muscles widely vary across individuals, even during a mechanically constrained ...
Tópico(s): Sports Performance and Training
2020 - American Physiological Society | Journal of Applied Physiology
Inés Cerón, Patricia Muñóz, Mercedes Marín, A. Segado, J. Roda, Maricela Valerio, Emilio Bouza, Javier Bermejo, Emilio Bouza, Alia Eworo, Ana Fernández‐Cruz, Gregorio Cuerpo, José Antonio García Robles, Marcela González del Vecchio, Ana García Mansilla, Víctor José González Ramallo, Martha Kestler, Mercedes Marín, Manuel Martínez‐Sellés, Ma Cruz Menárguez, Patricia Muñóz, Enrique Pérez Gutiérrez, B. Pinilla, Ángel Pinto, J. Roda, Marta Rodríguez‐Créixems, Hugo Rodríguez, Manuel Ruiz‐Aravena, Maria Aurora Posadas Salas, A. Segado, Maricela Valerio, Pilar Vázquez, Eduardo Verde,
ObjectivesEnterococcus spp. account for 10% of infective endocarditis (IE). Although daptomycin is a bactericidal drug with in vitro activity against Enterococcus, there is little experience of its use in IE. We analysed the effectiveness of daptomycin in the treatment of enterococcal IE (EIE).
Tópico(s): Streptococcal Infections and Treatments
2014 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Carla Domingues Santos, Míriam Paula Alonso Toldo, Fabrícia Helena Santello, Marina Del Vecchio Filipin, Vânia Brazão, José Clóvis do Prado Júnior,
Dehydroepiandrosterone (DHEA) enhances immune responses against a wide range of viral, bacterial, and parasitic pathogens. In a previous study, we reported that administration of DHEA significantly decreased the numbers of blood parasites in Trypanosoma cruzi experimental infection. The present study was undertaken to determine the effectiveness of DHEA in reducing the severity of acute phase T. cruzi infection of male and female Wistar rats. Animals were treated subcutaneously with 40 mg/kg body ...
Tópico(s): Research on Leishmaniasis Studies
2008 - Elsevier BV | Veterinary Parasitology
Produção Nacional
Revisado por pares
Polianna Delfino-Pereira, Poliana Bertti-Dutra, Flávio Del Vecchio, José Antônio Cortes de Oliveira, Daniel de Castro Medeiros, Daniel Moreira Cestari, Victor Rodrigues Santos, Márcio Flávio Dutra Moraes, João Luís Garcia Rosa, Eduardo Mazoni Andrade Marçal Mendes, Norberto Garcia‐Cairasco,
Background: Clinical and experimental evidence indicates that olfactory stimulation modulates limbic seizures, either blocking or inducing ictal activity. Objective: We aim to evaluate the behavioral and electroencephalographic (EEGraphic) effects of dihydro-2,4,5-trimethylthiazoline (TMT) olfactory exposure on limbic seizures induced by amygdala rapid kindling (ARK). Materials and Methods: Wistar male rats (280-300 g) underwent stereotaxic surgery for electrode implantation in piriform cortex (PC), ...
Tópico(s): Memory and Neural Mechanisms
2020 - Frontiers Media | Frontiers in Neurology
Lara García-Álvarez, M Mercedes Sanz, Mercedes Marín, M. Carmen Fariñas, Miguel Montejo, Josune Goikoetxea, Raquel Rodríguez-García, Arístides de Alarcón, Manuel Almela, Núria Fernández-Hidalgo, M. M. Alonso Socas, Miguel Ángel Goenaga, Enrique Navas, Luís Vicioso, José A. Oteo, Fernando Fernández Sánchez, Mariam Noureddine, Gabriel Rosas, Javier de la Torre, José I. Aramendi, Elena Bereciartúa, María Victoria Boado, Marta Campaña Lázaro, Josune Goikoetxea, J.J. Goiti, José L. Hernández, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Pedro María Pérez, Regino Rodríguez, Roberto Voces, Radka Ivanova Georgieva, Manuel Márquez, Isabel Rodríguez Bailón, Josefa Ruíz Morales, Ana María Cuende, Tomás Echeverría, Ana Fuerte, Eduardo Gaminde, Miguel Ángel Goenaga, Pedro Idígoras, José Antonio Iribarren, Alberto Izaguirre Yarza, Xabier Kortajarena Urkola, Carlos Reviejo, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Nemesio Álvarez, José María Bravo-Ferrer, Laura Castelo, José J. Cuenca‐Castillo, Pedro Llinares, Enrique Míguez Rey, María Rodríguez Mayo, Efrén Sánchez, Dolores Sousa Regueiro, Francisco António, M.M. Alonso, Beatriz Castro, Dácil García Marrero, Ma del Carmen Durán, Ma Antonia Miguel Gómez, Juan La Calzada, Ibrahim Nassar, Antonio Pláta Ciézar, José Ma Reguera Iglesias, Víctor Asensi, Carlos Costas, Jesús de la Hera, Jonathan Fernández-Suárez, Lisardo Iglesias Fraile, Víctor León, José López Menéndez, Pilar Mencía Bajo, Carlos Montilla, Alfonso Moreno Torrico, Carmen Palomo, B. Martínez, Ángeles Rodríguez Esteban, Raquel Rodríguez-García, Mauricio Telenti Asensio, Manuel Almela, Juan Ambrosioni, Yolanda Armero, Manuel Azqueta, Merçè Brunet, Ramón Cartañá, Carlos Falces, Guillermina Fita, David Fuster, Cristina García de la Mària, José M. Gatell, Jaume Llopis Pérez, Christian Manzardo, Francesc Marco, José M. Miró, Asunción Moreno, Salvador Pié i Ninot, Eduard Quintana, Carlos Paré, Daniel Pereda, Juan M. Pericàs, José Luís Pomar, José Ramírez, Irene Rovira, Marta Sitges, Dolors Soy, Adrián Téllez, Bárbara Vidal, Jordi Vilà, Javier Bermejo, Emilio Bouza, Gregorio Cuerpo, Viviana de Egea, Alia Eworo, Ana Fernández‐Cruz, Ma Eugenia García Leoni, Marcela González del Vecchio, Víctor José González Ramallo, Martha Kestler Hernández, Mercedes Marín, Manuel Martínez‐Sellés, Ma Cruz Menárguez, Patricia Muñóz, Cristina Rincón, Hugo Rodríguez-Abella, Marta Rodríguez‐Créixems, Blanca Pinilla, Ángel Pinto, Maricela Valerio, Eduardo Verde Moreno, Isabel Antorrena, Belén Loeches, Mar Moreno, Ulises Ramírez, Verónica Rial Bastón, María Romero, Araceli Saldaña, Carlos Armiñanzas Castillo, Ana María Arnáiz-García, José R. Berrazueta, Sara Bellisco, Manuel Cobo Belaustegui, Raquel Rodríguez-García, MaCarmen Fariñas, Concepción Fariñas-Álvarez, Carlos Fernández Mazarrasa, Rubén Gómez Izquierdo, Claudia Gonzalez‐Rico, José Gutiérrez Díez, Rafael Martín Durán, Marcos Pajarón, José Antonio Parra, Ramón Teira, Jesús Zarauza, Pablo García Pavía, Jesús Santos González, Beatriz Orden, António Ramos, Elena Rodríguez‐González, Tomasa Centella, José Manuel Hermida, José Luis Betrán Moya, Pilar Martín‐Dávila, Enrique Navas, Enrique Oliva, Alejandro del Río, Soledad Ruíz, Carmen Hidalgo Tenorio, Antonio de Castro, Marina de Cueto, Pastora Gallego, Juan Gálvez-Acebal, Jesús Rodríguez‐Baño, Arístides de Alarcón, Emilio Gutiérrez, Juan Luis Haro, José Antonio Lepe, Francisco López, Rafael Luque, Luis Javier Alonso, Pedro Azcárate, José Manuel Azcona, José Ramón Blanco, Lara García-Álvarez, José A. Oteo, Mercedes Sanz, Natividad Benito, Mercè Gurguí, Cristina Pacho, R. Pericás, Guillem Pons, Mar Álvarez, Ángel L. Fernández, Amparo Martínez, A. Prieto, Benito Regueiro, E. Tijeira, E Marino Vega, Andrés Canut Blasco, José Cordo Mollar, Juan Carlos Gainzarain Arana, Oscar García Uriarte, Alejandro Martín López, Zuriñe Ortiz de Zárate, José Antonio Urturi Matos, Ma Belén Nacle, Antonio Sánchez-Porto, Luis Vallejo, José María Arribas, Elisa García Vázquez, Alicia Hernández Torres, Ana Lozano-Blázquez, Gonzalo de la Morena, Ángel Barajas, Javier Aramburu, Felicitas Elena Calvo, Anai Moreno Rodríguez, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, José Largo Pau, Ma Antonia Sepúlveda, Pilar Toledano Sierra, Sadaf Zafar Iqbal-Mirza, Eva Cascales Alcolea, Pilar Egea Serrano, Jose Roca, Eduardo Moreno Escobar, Alejandro Peña Monje, Valme Sánchez Cabrera, David Vinuesa García, Carmen Luna, Juana Núñez Morcillo, Ma Cruz Pérez Seco,
Tropheryma whipplei has been detected in 3.5% of the blood culture-negative cases of endocarditis in Spain. Experience in the management of T. whipplei endocarditis is limited. Here we report the long-term outcome of the treatment of previously reported patients who were diagnosed with infective endocarditis (IE) caused by T. whipplei from the Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES) and discuss potential options for antimicrobial ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2019 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Vânia Brazão, Fabrícia Helena Santello, Leony Cristina Caetano, Marina Del Vecchio Filipin, Míriam Paula Alonso Toldo, José Clóvis do Prado Júnior,
Chagas' disease is considered the sixth most important neglected tropical disease worldwide. Considerable knowledge has been accumulated concerning the role of zinc on cellular immunity. The steroid hormone dehydroepiandrosterone (DHEA) is also known to modulate the immune system. The aims of this paper were to investigate a possible synchronization of their effects on cytokines and NO production and the resistance to Trypanosoma cruzi during the acute phase of infection. It was found that zinc, ...
Tópico(s): Research on Leishmaniasis Studies
2009 - Elsevier BV | Immunobiology
Alessandro Del Vecchio, Andrés Úbeda, Massimo Sartori, José M. Azorín, Francesco Felici, Dario Farina,
Force is generated by muscle units according to the neural activation sent by motor neurons. The motor unit is therefore the interface between the neural coding of movement and the musculotendinous system. Here we propose a method to accurately measure the latency between an estimate of the neural drive to muscle and force. Furthermore, we systematically investigate this latency, which we refer to as the neuromechanical delay (NMD), as a function of the rate of force generation. In two experimental ...
Tópico(s): EEG and Brain-Computer Interfaces
2018 - American Physiological Society | Journal of Applied Physiology
Produção Nacional
Revisado por pares
Bianca Miarka, Fabrício Boscolo Del Vecchio, Ciro José Brito, Montassar Tabben, John Amtmann, Karim Chamari,
The aim of this study was to compare time-motion and technical analysis in mixed martial arts (MMA) home advantage situation with paired bouts of the same athletes in home and away matches. For this purpose, we analyzed, 202 bouts and 606 rounds from UFC™ events (2012-2014), paired by both athletes competing at home (n=101) or away (n=101). The time-motion variables were categorized into low or high intensity, standup or groundwork situations. Techniques were analyzed by observing total strikes to the ...
Tópico(s): Sport Psychology and Performance
2016 - Taylor & Francis | International Journal of Performance Analysis in Sport
Timothy J. Whelan, Jim A. Julian, Tanya Berrang, Do‐Hoon Kim, Isabelle Germain, Alan Nichol, Mohamed Akra, Sophie Lavertu, François Germain, Anthony Fyles, Theresa Trotter, Francisco Perera, Susan Balkwill, Susan Chafe, Thomas McGowan, Thierry Muanza, Wayne Beckham, Boon Chua, Chu Shu Gu, Mark N. Levine, Ivo A. Olivotto, Carson Leong, Beverly Lester, Winkle Kwan, Medhat Zikry Abd-El-Malek, Arthur Cheung, Maha Almahmudi, J.A. Broomfield, Michael Sia, Melanie Reed, J. Frank Wilson, Islam Mohamed, Caroline Holloway, Ken Mills, David Petrik, Juanita Crook, Frances Wong, Hannah Carolan, D. Voduc, Paris‐Ann Ingledew, Sonia Nguyen, Mira Keyes, Lorna Weir, Scott Tyldesley, Peter Lim, Christina Parsons, Robert Olson, Paul Blood, Elaine S. Wai, Pauline T. Truong, Hosam A. Kader, Abraham Alexander, Aminudin R. Mydin, Sally Smith, María T. Vlachaki, Valérie Panet-Raymond, Krystine Lupe, Jennifer Goulart, David H. Nguyen, Karen Chu, Joycelin Canavan, Julianna Caon, Susan A. Tyler, Negin Shahid, Jacqueline Lam, John Amanie, Diane Severin, Bassam Abdul Karim, Keith Tankel, Nadeem Pervez, Kurian Joseph, Zsolt Gabos, Barbara Krause, Fleur Huang, Tien Phan, Peter Craighead, Elizabeth Yan, Jill MacKinnon, Robert Nordal, Siraj Husain, Jon-Paul Voroney, Richie Sinha, James Pinilla, Andrew Cooke, Kalyani Vijayraghavan, Steven Latosinsky, Elizabeth Saettler, Yiu-Keung Lau, Marianne Krahn, Ethel MacIntosh, Maged N. F. Nashed, Bashir Bashir, Valter Torri, Benjamin A. Goldenberg, Christina Kim, V. Basrur, Ramana Rachakonda, Darin Gopaul, Sundeep Shahi, Sofya Kobeleva, Ian S. Dayes, David Hodson, Barbara Strang, S. Voruganti, William McMillan, Harold Reiter, James R. Wright, Jonathan Sussman, Som D. Mukherjee, Susan Gudelis, David D’Souza, Michael Lock, Nancy Read, Olga Vujovic, Brian Yaremko, Edward Yu, Theodore A. Vandenberg, Jawaid Younus, Kylea Potvin, Tracy Sexton, B. Dingle, B. Findlay, Janice Giesbrecht, Philip F. Hughes, Martin Samosh, Michael A. Levesque, Radhika Yelamanchili, Linda Lee, R Vandermeer, David H. Wasserman, Julie Bowen, David Want, Randall Bissett, A. Andronowski, Sarwat Shehata, Hugh L. Prichard, Wayne Koll, Philip C. Y. Chan, Jimmy Mui, Youssef M. Youssef, Holly R. Campbell, Medhat El-Mallah, Fawaad Iqbal, Behzad Banihashemi, Peter H. Dixon, L. Grimard, C. Lochrin, Joanne Meng, P. Cross, Samy El‐Sayed, B. Esche, P. Genest, Jean-Michel Caudrelier, Scott C. Morgan, Jean‐Marc Bourque, Vimoj Nair, Senti Senthelal, Glenn Jones, Jonathan Tsao, John Radwan, Charles Hayter, M. Finlay, JD Lian, Yongjin Wang, Jasper Yuen, Luleul Khan, B.C. John Cho, Christine Koch, Fei‐Fei Liu, L. Manchul, Michael McLean, Pamela Catton, Robert Dinniwell, Woodrow Wells, Wilfred Levin, Lorraine Walsh, Caroline Chung, Kathy Han, Tatiana Conrad, Joelle Helou, Aisling Barry, K Schneider, Khalid Hirmiz, Hakam Abu-Zahra, Isabelle Roy, Jose Ayllon, Pierre Del Vecchio, Marie-Andrée Fortin, Jean‐Pierre Guay, F Méthot, Pierre Rousseau, M. Jolicoeur, Toni Vu, Levon Igidbashian, Anne Dagnault, Luis-Victor Diaz de Bedoya, Chang Shu Wang, A. Fortin, Éric Vigneault, Isabelle Vallières, Paul-Émile Raymond, André‐Guy Martin, Lucie Blondeau, Marie Larochelle, N. Lessard, M Gaudreault, Valérie Théberge, Abdenour Nabid, Olivier Ballivy, Rachel Bujold, Annie Ébacher, Sawyna Provencher, Pierre Chabot, Céline Lemaire, Peter Vavassis, C. Menkarios, Michael Yassa, Khalil Sultanem, Lawrence Panasci, David Melnychuk, François Patenaude, Wilson H. Miller, Catalin Mihalioiu, P.D. Ahlgren, Richard Dalfen, Adrian Langleben, Donna Stern, Jonathan Wan, Christine Lambert, Marc David, Neil Kopek, Annie Carbonneau, Tarek Hijal, Nancy J. Grant, Farah Naz, M. Mohiuddin, Sri Kumar, Robert Rutledge, D. Rheaume, Maureen Nolan, Wladyslawa Cwajna, Suki Gill, Tracie Gleisner, Solveig Grenfell, Michelle Bishop, Niluja Thiruthaneeswaran, Chen Liu, Claire Philips, Roslyn Drummond, Bronwyn King, Steven David, Mary Dwyer, Gillian Campbell, Susan A. Brooks, Ramesh Arunachalam, Giuseppe Sasso, Chelleraj Benjamin, Chakiath Jose, Christine Elder, Hedley Krawitz, Dominique Lee, Roger Huang, Sudha Purchuri, Maria Pearse, Thayavalappil Hemanth, Ruth Angell, Vikash Patel, Glenys Round, Anupam Chaudhuri, C. H. J. Ford,
Background Whole breast irradiation delivered once per day over 3–5 weeks after breast conserving surgery reduces local recurrence with good cosmetic results. Accelerated partial breast irradiation (APBI) delivered over 1 week to the tumour bed was developed to provide a more convenient treatment. In this trial, we investigated if external beam APBI was non-inferior to whole breast irradiation. Methods We did this multicentre, randomised, non-inferiority trial in 33 cancer centres in Canada, Australia ...
Tópico(s): Breast Lesions and Carcinomas
Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
Gaia Sampogna, Giovanni Marcos Lovisi, Francesca Zinno, Valeria Del Vecchio, Mario Luciano, Érika Gonçalves Loureiro Sol, Roberto José Gervásio Unger, Antonio Ventriglio, Andrea Fiorillo,
Background and objectives: The presence of mental health problems in the population of medical students in Italy has been evaluated in several cross-sectional studies, which have used different methodologies and study designs. However, a global overview of the prevalence of mental health problems in Italian medical students is not available, although this would be essential for promoting preventive strategies and supportive treatments. Materials and Methods: An integrative review aiming to describe ...
Tópico(s): Health and Well-being Studies
2020 - Multidisciplinary Digital Publishing Institute | Medicina
Produção Nacional
Revisado por pares
Vânia Brazão, Leony Cristina Caetano, Marina Del Vecchio Filipin, Míriam Paula Alonso Toldo, Luana Naiara Caetano, José Clóvis do Prado Júnior,
Tópico(s): Parasitic Infections and Diagnostics
2008 - Elsevier BV | Veterinary Parasitology
Produção Nacional
Revisado por pares
Vânia Brazão, Leony Cristina Caetano, Marina Del Vecchio Filipin, Fabrícia Helena Santello, Míriam Paula Alonso Toldo, José Clóvis do Prado Júnior,
Zinc is an essential nutritional component required for normal development and maintenance of immune functions. The possible effects of zinc in upregulating the host immune response during the acute and chronic phases of experimental Chagas’ disease were evaluated. In young, infected and Zn-supplemented animals, higher concentrations of IFN-γ and NO were observed. During the chronic phase, decreased concentrations of NO and IFN-γ were found for older infected animals that received Zn supplementation. ...
Tópico(s): Research on Leishmaniasis Studies
2008 - Elsevier BV | Experimental Parasitology
Alberto Ortíz, Charles J. Ferro, Olga Balafa, Michel Burnier, Robert Ekart, Jean‐Michel Halimi, Reinhold Kreutz, Patrick B. Mark, Alexandre Persu, Patrick Rossignol, Luís M. Ruilope, Roland E. Schmieder, José Manuel Valdivielso, Lucia Del Vecchio, Carmine Zoccali, Francesca Mallamaci, Pantelis Sarafidis,
Diabetic kidney disease (DKD) develops in ∼40% of patients with diabetes and is the most common cause of chronic kidney disease (CKD) worldwide. Patients with CKD, especially those with diabetes mellitus, are at high risk of both developing kidney failure and cardiovascular (CV) death. The use of renin-angiotensin system (RAS) blockers to reduce the incidence of kidney failure in patients with DKD dates back to studies that are now ≥20 years old. During the last few years, sodium-glucose co-transporter- ...
Tópico(s): Ion Transport and Channel Regulation
2021 - Oxford University Press | Nephrology Dialysis Transplantation
Yili Qian, Hsin-Ho Huang, José I. Jiménez, Domitilla Del Vecchio,
A common approach to design genetic circuits is to compose gene expression cassettes together. While appealing, this modular approach is challenged by the fact that expression of each gene depends on the availability of transcriptional/translational resources, which is in turn determined by the presence of other genes in the circuit. This raises the question of how competition for resources by different genes affects a circuit's behavior. Here, we create a library of genetic activation cascades ...
Tópico(s): Bacterial Genetics and Biotechnology
2017 - American Chemical Society | ACS Synthetic Biology
Orlando Vieira de Sousa, Glauciemar Del-Vecchio Vieira, José J. R. G. Pinho, Maria Silvana Alves, Maria Auxiliadora Coelho Kaplan,
Tópico(s): Traditional and Medicinal Uses of Annonaceae
2011 - College of Pharmacists of Buenos Aires Province | Latin American Journal of Pharmacy