Maria José Soares Mendes‐Giannini, Juliana Leal Monteiro da Silva, Julhiany de Fátima da Silva, Fabiana Cristina Donofrio, Elaine Toscano Miranda, Patrícia Ferrari Andreotti, Christiane Pienna Soares,
Host-fungal interactions are inherently complex and dynamic. In order to identify new microbial targets and develop more effective anti-fungal therapies, it is important to understand the cellular and molecular mechanisms of disease. Paracoccidioidomycosis provokes a variety of clinical symptoms, and Paracoccidioides brasiliensis can reach many tissues, but primarily attacks the lungs. The ability of the pathogen to interact with the host surface structures is essential to further colonization, ...
Tópico(s): Plant Pathogens and Fungal Diseases
2007 - Springer Science+Business Media | Mycopathologia
Produção Nacional
Revisado por pares
Israel José dos Santos Felipe, Wesley Mendes‐Da‐Silva, Cristiana Cerqueira Leal, Danilo Braun Santos,
The time-to-success of reward crowdfunding campaigns constitutes a relevant topic that has been neglected in business literature. In this study, we employ parametric and semi-parametric models of survival analysis to identify the determining factors of the duration of success of these campaigns. Based on more than 4200 reward crowdfunding campaigns, our results are robust for controls and reveal that the campaigns that attain success most rapidly are located predominantly in cities with greater ...
Tópico(s): Sharing Economy and Platforms
2021 - Elsevier BV | Journal of Business Research
Produção Nacional
Revisado por pares
Denise Mendes da Silva, Edvalda Araújo Leal, Janser Moura Pereira, José Dutra de Oliveira Neto,
Objective – The objective of the study is to identify whether learning styles impact academic performance and online and face-to-face assessment activities in Distance Education.Design/methodology/approach – Learning styles were mapped using the Index of Learning Styles (ILS) of Felder and Soloman (1991). For data analysis, generalized linear models methodology was adopted; the Wald test was used to evaluate the effect of the factors.Theoretical foundation - This research is based on cognitive theory. The ...
Tópico(s): Online Learning and Analytics
2015 - Álvares Penteado School of Commerce Foundation | Review of Business Management
Produção Nacional
Revisado por pares
Maria José Soares Mendes‐Giannini, Samira Abdallah Hanna, Juliana Leal Monteiro da Silva, Patrícia Ferrari Andreotti, Luciana Raquel Vincenzi, Gil Benard, Henrique Leonel Lenzi, Christiane Pienna Soares,
Paracoccidioides brasiliensis (Pb) yeast cells can enter mammalian cells and probably manipulate the host cell environment to favor their own growth and survival. We studied the uptake of strain Pb 18 into A549 lung and Vero epithelial cells, with an emphasis on the repercussions in the cytoskeleton and the apoptosis of host cells. Cytoskeleton components of the host cells, such as actin and tubulin, were involved in the P. brasiliensis invasion process. Cytochalasin D and colchicine treatment substantially ...
Tópico(s): Plant Pathogens and Fungal Diseases
2004 - Elsevier BV | Microbes and Infection
Produção Nacional
Revisado por pares
Luiz Augusto Pereira, Sà ́nia Nair Báo, Mà ́nica Santiago Barbosa, Juliana Leal M. da Silva, Maria Sueli Soares Felipe, Jaime M. Santana, Maria José Soares Mendes‐Giannini, Célia Maria de Almeida Soares,
Paracoccidioides brasiliensis is an important fungal pathogen. The disease it causes, paracoccidioidomycosis (PCM), ranges from localized pulmonary infection to systemic processes that endanger the life of the patient. Paracoccidioides brasiliensis adhesion to host tissues contributes to its virulence, but we know relatively little about molecules and the molecular mechanisms governing fungal adhesion to mammalian cells. Triosephosphate isomerase (TPI: EC 5.3.1.1) of P. brasiliensis (PbTPI) is a fungal ...
Tópico(s): Nail Diseases and Treatments
2007 - Oxford University Press | FEMS Yeast Research
Produção Nacional
Revisado por pares
Lucas Lopes Araújo SOUSA, Wagner Leal Serra e Silva Filho, Regina Ferraz Mendes, José Machado Moita Neto, Raimundo Rosendo Prado Júnior,
To assess the impact of hospitalization on the oral health status of individuals hospitalized for a short period of time.This was an observational study of hospitalized patients. The plaque index (PI), gingival index (GI) was measured at baseline (T0 - first 24 h of hospital admission), and at 3 (T1), 7 (T2), 14 (T3) days.One hundred and sixty-two patients were examined at baseline (T0), 35 examined at 3 days (T1), 23 at 7 days (T2) and 16 at 14 days (T3). The main reason for loss of patients was hospital discharge. ...
Tópico(s): Oral health in cancer treatment
2014 - Wiley | Journal Of Clinical Periodontology
Produção Nacional
Revisado por pares
João Victor da Silva Guerra, José Oliveira dos Santos, Danyllo Oliveira, Gabriela Ferraz Leal, João Ricardo Mendes de Oliveira, Silvia Souza da Costa, Ana Cristina Victorino Krepischi, Angela Maria Vianna‐Morgante, Mariana Maschietto,
Mutations in KDM5C (lysine (K)-specific demethylase 5C) were causally associated with up to 3% of X-linked intellectual disability (ID) in males. By exome and Sanger sequencing, a novel frameshift KDM5C variant, predicted to eliminate the JmjC catalytic domain from the protein, was identified in two monozygotic twins and their older brother, which was inherited from their clinically normal mother, who had completely skewed X-inactivation. DNA methylation (DNAm) data were evaluated using the Illumina ...
Tópico(s): Genetic Syndromes and Imprinting
2019 - Elsevier BV | European Journal of Medical Genetics
Produção Nacional
Revisado por pares
Adriana Del Vecchio, Julhiany de Fátima da Silva, Juliana Leal Monteiro da Silva, Patrícia Ferrari Andreotti, Christiane Pienna Soares, Gil Benard, Maria José Soares Mendes‐Giannini,
Paracoccidioidomycosis presents a variety of clinical manifestations and Paracoccidioides brasiliensis can reach many tissues, most importantly the lungs. The ability of the pathogen to interact with host surface structures is essential to its virulence. The interaction between P. brasiliensis and epithelial cells has been studied, with particular emphasis on the induction of apoptosis. To investigate the expression of different apoptosis-inducing pathways in human A549 cells, we infected these ...
Tópico(s): Cell death mechanisms and regulation
2009 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Maria José Soares Mendes‐Giannini, Patrícia Ferrari Andreotti, Luciana Raquel Vincenzi, Juliana Leal Monteiro da Silva, Henrique Leonel Lenzi, Gil Benard, R M Zancopé-Oliveira, Herbert Leonel de Matos Guedes, Christiane Pienna Soares,
Tópico(s): Nail Diseases and Treatments
2006 - Elsevier BV | Microbes and Infection
Produção Nacional
Revisado por pares
Julhiany de Fátima da Silva, Juliana Vicentim, Haroldo César de Oliveira, Caroline Maria Marcos, Patrícia Akemi Assato, Patrícia Ferrari Andreotti, Juliana Leal Monteiro da Silva, Christiane Pienna Soares, Gil Benard, Ana Marisa Fusco‐Almeida, Maria José Soares Mendes‐Giannini,
The fungal strain Paracoccidioides brasiliensis remains viable inside of epithelial cells and can induce apoptosis in this population. However, until now, the molecules that participate in this process remained unknown. Thus, this study evaluated the contribution of two P. brasiliensis molecules, the 14-3-3 and glycoprotein of 43 kDa proteins, which had been previously described as extracellular matrix adhesins and apoptosis inductors in human pneumocytes. Accordingly, epithelial cells were treated ...
Tópico(s): Plant Disease Resistance and Genetics
2015 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Alisson Mendes Rodrigues, José Manuel Rivas Mercury, Valdemar Silva Leal, Aluísio A. Cabral,
Several analytical models have been widely applied to determine the activation energy of crystallization, E, and the Avrami index, n. In this work, the parameters E and n for the crystallization of fresnoite (2BaO·TiO2·2SiO2) glass were calculated using different approaches (Ozawa, Kissinger, and Matusita & Sakka). Monolithic glass samples (≈ 36 mg) were heated in a DSC furnace from room temperature to 650 °C at 40 °C/min, and held at that temperature for 5 min. To induce the formation of new nuclei mostly ...
Tópico(s): Thermal and Kinetic Analysis
2012 - Elsevier BV | Journal of Non-Crystalline Solids
Produção Nacional
Revisado por pares
Francisca Taciana Sousa Rodrigues, Caren Nádia Soares de Sousa, Naiara Coelho Ximenes, Anália Barbosa Almeida, Lucas Moraes Cabral, Cláudio Felipe Vasconcelos Patrocínio, Aline Holanda Silva, Luzia Kalyne Almeida Moreira Leal, José Eduardo Ribeiro Honório Júnior, Danielle S. Macêdo, Silvânia Maria Mendes Vasconcelos,
The objective of this study was to verify a possible neuroprotective effect of the ethanolic extract of Erythrina velutina (EEEV). Male Swiss mice were submitted to transient cerebral ischemia by occlusion of both carotid arteries for 30 min and treated for 5 days with EEEV (200 or 400 mg/kg) or Memantine (MEM) 10 mg/kg, with initiation of treatment 2 or 24 h after Ischemia. On the 6th day after the induction of ischemia, the animals were submitted to evaluation of locomotor activity and memory and ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2017 - Elsevier BV | Biomedicine & Pharmacotherapy
Produção Nacional
Revisado por pares
Pauline Lorena Kale, Sandra Costa Fonseca, Kátia Silveira da Silva, Penha Maria Mendes da Rocha, Rosana Garcia Silva, Alinne Christina Alves Pires, Maria de Lourdes Tavares Cavalcanti, Antônio José Leal Costa, Tania Zdenka Guillén de Torres,
Smoking epidemic in Brazilian women has later onset, smaller magnitude, and slower decreasing trend, compared to men. Among pregnant women, smoking has an additional deleterious effect. The purpose of this study was to analyze smoking prevalence during pregnancy and associated factors, and to describe the frequency of smoking reduction and cessation in public maternities of Rio de Janeiro State, southeastern Brazil, in 2011.A cross-sectional study was conducted in two maternities located at public ...
Tópico(s): Breastfeeding Practices and Influences
2015 - BioMed Central | BMC Public Health
Produção Nacional
Revisado por pares
Patrícia Ferrari Andreotti, Juliana Leal Monteiro da Silva, Alexandre Melo Bailão, Célia Maria de Almeida Soares, Gil Benard, Christiane Pienna Soares, Maria José Soares Mendes‐Giannini,
The virulence of Paracoccidioides brasiliensis can be attenuated or lost after long periods of repeated subculturing and reestablished after animal inoculation. Only one adhesin (gp43) has been described until now, among the various identified components of P. brasiliensis, and gp43 shows adhesion to laminin. Thus, the present study was designed to isolate and characterize factors putatively related to the capacity of this fungus to adhere to the host by comparing P. brasiliensis samples, taken before ...
Tópico(s): Antifungal resistance and susceptibility
2005 - Elsevier BV | Microbes and Infection
Produção Nacional
Revisado por pares
Mércia Marques Jucá, Francisco Maurício Sales Cysne Filho, Jamily Cunha de Almeida, Dara da Silva Mesquita, Jéssica Rodrigues de Moraes Barriga, Kátia Cilene Ferreira Dias, Talita Matias Barbosa, Luna Costa Vasconcelos, Luzia Kalyne Almeida Moreira Leal, José Eduardo Ribeiro, Silvânia Maria Mendes Vasconcelos,
Flavonoids have aroused much interest in research, since they present a great diversity of biological activities observed in vitro, such as: antioxidant effect, modulation of the enzymatic activity and inhibition of cellular proliferation, exerting beneficial effects on the organism, as well as the use of its therapeutic potential. With wide distribution in the plant kingdom represent a class of phenolic compounds that differ in their chemical structure and particular characteristics. The objective ...
Tópico(s): Bee Products Chemical Analysis
2018 - Taylor & Francis | Natural Product Research
Produção Nacional
Revisado por pares
Roseli Barbosa, Y. Cruz-Mendes, Kerly Shamyra da Silva‐Alves, Francisco Walber Ferreira‐da‐Silva, N.M. Ribeiro, Luís Pereira-de-Morais, José Henrique Leal‐Cardoso,
Lippia sidoides Cham is a typical herb species of Northeast Brazil with widespread use in folk medicine. The major constituents of the essential oil of L. sidoides (EOLs) are thymol, p-cymene, myrcene, and caryophyllene. Several studies have shown that the EOLs and its constituents have pharmacological effects, including antibacterial, anti-inflammatory, antioxidant and neuroprotective activity. Therefore, this work aimed to investigate the effects of the EOLs and their main constituents on rat sciatic ...
Tópico(s): Natural product bioactivities and synthesis
2017 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Francisco Norberto de Moura Neto, Ana Cristina Vasconcelos Fialho, Walter Leal de Moura, Adriana Gadelha Ferreira Rosa, José Milton Elias de Matos, Fernando da Silva Reis, Milton Thélio de Albuquerque Mendes, Elton Santos Dias Sales,
Bone fractures to be corrected need stabilization of their extremities, which is achieved with the use of plates and screws. This research aimed to produce castor bean polyurethane (Ricinus communis), to make resorbable plate, structural and thermal analysis. The production was made by the glycerolysis of the triglycerides present in the oil, after addition of polyol/glycerol and hexamethylene diisocyanate (HDI) to form urethane structures, with and without addition of hydroxyapatite. The characterization ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2019 - Associação Brasileira de Polímeros | Polímeros
Produção Nacional
Revisado por pares
Ariclécio Cunha de Oliveira, Sandra Andreotti, Talita da Silva Mendes de Farias, Francisco Leonardo Torres‐Leal, André Ricardo Gomes de Proença, Amanda Baron Campaña, Arnaldo Henrique de Souza, Rogério Antônio Laurato Sertié, Ângelo Rafael Carpinelli, José Cipolla‐Neto, Fábio Bessa Lima,
Diabetes mellitus is a product of low insulin sensibility and pancreatic β-cell insufficiency. Rats with streptozotocin-induced diabetes during the neonatal period by the fifth day of age develop the classic diabetic picture of hyperglycemia, hypoinsulinemia, polyuria, and polydipsia aggravated by insulin resistance in adulthood. In this study, we investigated whether the effect of long-term treatment with melatonin can improve insulin resistance and other metabolic disorders in these animals. At ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2012 - Oxford University Press | Endocrinology
Produção Nacional
Revisado por pares
Wesley Mendes‐Da‐Silva, Israel José dos Santos Felipe, Cristiana Cerqueira Leal, Marcelo Otone Aguiar,
We study whether the tone of daily news in mass media as a proxy for market sentiment affects the typical daily pledge amount in reward crowdfunding campaigns. Based on unique data for over 350,000 pledges in reward crowdfunding campaigns from over 2,600 cities in Brazil, we find that market sentiment affects the willingness of backers to make larger pledges. Our unprecedented results reveal that good news induces larger pledges. The effect of tone on pledge amounts is inhibited by the geographic ...
Tópico(s): Sharing Economy and Platforms
2022 - Wiley | Journal of Small Business Management
Produção Nacional
Revisado por pares
L.E.R. Vega, Daniel Rodrigo Leiva, Ricardo Mendes Leal Neto, Wágner Batista Silva, Rafael Silva, Tomaz Toshimi Ishikawa, Cláudio Shyinti Kiminami, Walter José Botta Filho,
In this study, we propose a method to produce nanocrystalline TiFe powder by high-energy ball milling, in order to avoid the common sticking problem of the material to the milling tools, assuring a material prompt to absorb hydrogen as well. The method consists of making a preliminary milling operation with the elemental powders (50:50 stoichiometric ratio) to form a strong adhered layer of the milled material on the surfaces of the vial and balls. The main milling operation is then performed with ...
Tópico(s): Nanomaterials for catalytic reactions
2019 - Elsevier BV | International Journal of Hydrogen Energy
Produção Nacional
Revisado por pares
Marisa Jádna Silva Frederico, Allisson Jhonatan Gomes Castro, Alessandra Mascarello, Camila Pires Mendes, Virginia Dermachi Kappel, Taisa Regina Stumpf, Paulo César Leal, Ricardo José Nunes, Rosendo Augusto Yunes, Fátima Regina Mena Barreto Silva,
In this study the in vivo and in vitro antidiabetic effects of four acylhydrazone derivatives were investigated in rats. The secretagogue action, oral glucose tolerance, insulinogenic index and mechanism of action of these acylhydrazones in relation to calcium uptake in pancreatic islets were studied. Also, the insulinomimetic effect on glycemia in diabetic rats was verified. Of the acylhydrazones studied, 1 and 4 were able to increase glucose tolerance in an acute time-course. A powerful secretagogue ...
Tópico(s): Metabolism, Diabetes, and Cancer
2012 - Bentham Science Publishers | Current Topics in Medicinal Chemistry
Produção Nacional
Revisado por pares
Silvânia Maria Mendes Vasconcelos, Gabriel Teixeira Montezuma Sales, Natália da Silva Lima, Rodrigo de Freitas Guimarães Lobato, Danielle S. Macêdo, José Maria Barbosa‐Filho, Luzia Kalyne Almeida Moreira Leal, M.M.F. Fonteles, Francisca Cléa Florenço de Sousa, Jeania Lima Oliveira, Glauce S.B. Viana,
This work studied the anti-inflammatory activities of the hydroalcoholic extracts (HAEs) from Erythrina velutina Willd. (Ev) and E. mulungu Mart. ex Benth. (Em) in the carrageenan- and dextran-induced mice hind paw edema models. These medicinal plants belonging to the Fabaceae family are used in some Brazilian communities to treat pain, inflammation, insomnia and disorders of the central nervous system. In the present work, the extracts were administered orally in male mice at the doses of 200 or 400 ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2011 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Produção Nacional
Revisado por pares
Marisa Jádna Silva Frederico, Alessandra Mascarello, Allisson Jhonatan Gomes Castro, Gabrielle da Luz, Delsi Altenhofen, Camila Pires Mendes, Paulo César Leal, Rosendo Augusto Yunes, Ricardo José Nunes, Fátima Regina Mena Barreto Silva,
To characterize the role and the mechanism of action of (2E)-N'-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide (BZD) on incretin secretion, glucose uptake in skeletal muscle and α-glucosidase activity on intestine, targets for glucose homeostasis. It was assayed on glucose tolerance test (GTT) to analyze GLP-1 secretion and the activity of DPP-4 enzyme in vitro. In skeletal muscle, mechanism of action on glucose uptake was carried out by in vitro experiments. The activity of intestinal disaccharidases ...
Tópico(s): Pancreatic function and diabetes
2015 - Wiley | Journal of Cellular Biochemistry
Produção Nacional
Revisado por pares
Rafael Silva, Ricardo Mendes Leal Neto, Daniel Rodrigo Leiva, Tomaz Toshimi Ishikawa, Cláudio Shyinti Kiminami, Alberto Moreira Jorge, Walter José Botta Filho,
Mg - 40 wt % TiFe nanocomposite was prepared by high-energy ball milling, HEBM, aiming improved hydrogen absorption at room temperature (RT). Four processing routes were chosen to separately investigate the effects of TiFe addition, HEBM processing and dispersion of TiFe particles, being: Route 1 – mechanical mixture of Mg and TiFe powders; Route 2 – HEBM of Mg + TiFe at 400 rpm for 12 h; Route 3 – HEBM of pure Mg at 400 rpm for 12 h to be used as reference; and Route 4 – HEBM of Mg + TiFe at 600 rpm for 36 h. In ...
Tópico(s): Nanomaterials for catalytic reactions
2018 - Elsevier BV | International Journal of Hydrogen Energy
Produção Nacional
Revisado por pares
Leidiane Pinho‐da‐Silva, Paula Virgínia Mendes-Maia, Taylena Maria Teófilo, Roseli Barbosa, Vânia Marilande Ceccatto, Andrelina Noronha Coelho‐de‐Souza, Jáder Santos Cruz, José Henrique Leal‐Cardoso,
trans-Caryophyllene is a major component in the essential oils of various species of medicinal plants used in popular medicine in Brazil. It belongs to the chemical class of the sesquiterpenes and has been the subject of a number of studies. Here, we evaluated the effects of this compound in airway smooth muscle. The biological activities of trans-caryophyllene were examined in isolated bath organs to investigate the effect in basal tonus. Electromechanical and pharmacomechanical couplings were ...
Tópico(s): Natural Compounds in Disease Treatment
2012 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Talita da Silva Mendes de Farias, Ariclécio Cunha de Oliveira, Sandra Andreotti, Fernanda Gaspar do Amaral, Patrícia Chimin, André Ricardo Alves de Proença, Francisco Leonardo Torres‐Leal, Rogério Antônio Laurato Sertié, Amanda Baron Campaña, Andressa Bolsoni Lopes, Arnaldo Henrique de Souza, José Cipolla‐Neto, Fábio Bessa Lima,
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24-hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression (chronobiotic effect) and the modulation of several endocrine functions in peripheral tissues. Assuming that the circadian synchronization of clock genes can play a role in the regulation of energy metabolism and it is influenced by melatonin, our study was designed to assess ...
Tópico(s): Neurobiology and Insect Physiology Research
2015 - Wiley | Journal of Pineal Research
Produção Nacional
Revisado por pares
Leidiane Pinho‐da‐Silva, P.V. Mendes-Maia, T.M. do Nascimento Garcia, Jáder Santos Cruz, Selene Maia de Morais, Andrelina Noronha Coelho‐de‐Souza, Saad Lahlou, José Henrique Leal‐Cardoso,
Plants of the genus Croton have been used extensively in the northeast of Brazil for treating various clinical conditions. Previous studies have demonstrated that the essential oil of some specimens of Croton sp. have a relaxing effect on tracheal smooth muscle. Our study aimed to characterize the effects of Croton sonderianus essential oil samples, collected at 1:00 pm (EO-13) and 9:00 pm (EO-21), on rat tracheal smooth muscle. The two samples were submitted to gas chromatography (GC) and mass spectrometry ( ...
Tópico(s): Bioactive Natural Diterpenoids Research
2010 - Elsevier BV | Phytomedicine
Produção Nacional
Revisado por pares
Pedro Henrique Lopes da Silva, Katherine Kelda Gomes de Castro, Mayara Abud Mendes, Thyago Leal-Calvo, Júlia Monteiro Pereira Leal, José Augusto da Costa Nery, Euzenir Nunes Sarno, Roberto Alves Lourenço, Milton Ozório Moraes, Flávio Alves Lara, Danuza Esquenazi,
Leprosy is an infectious disease that remains endemic in approximately 100 developing countries, where about 200,000 new cases are diagnosed each year. Moreover, multibacillary leprosy, the most contagious form of the disease, has been detected at continuously higher rates among Brazilian elderly people. Due to the so-called immunosenescence, characterized by several alterations in the quality of the immune response during aging, this group is more susceptible to infectious diseases. In view of ...
Tópico(s): Cytomegalovirus and herpesvirus research
2021 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
José Eduardo Ribeiro Honório, Germana Silva Vasconcelos, Francisca Taciana Sousa Rodrigues, José Guedes de Sena Filho, José Maria Barbosa‐Filho, Carlos Clayton Torres Aguiar, Luzia Kalyne Almeida Moreira Leal, Pedro Marcos Gomes Soares, David Woods, Marta Maria de França Fonteles, Silvânia Maria Mendes Vasconcelos,
This work was designed to study MCT effect in histopathological analysis of hippocampus (HC) and parahippocampal cortex (PHC) and in oxidative stress (OS) parameters in brain areas such as hippocampus (HC), prefrontal cortex (PFC), and striatum (ST). Swiss mice (25–30 g) were administered a single i.p. dose of MCT (5, 50, or 100 mg/kg) or 4% Tween 80 in saline (control group). After 30 minutes, the animals were sacrificed by decapitation and the brain areas (HC, PHC, PFC, or ST) were removed for histopathological ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2012 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
... Faustino Xavier de Novais, Camilo Caste-lo Branco, José da Silva Mendes Leal e Guilherme Braga. Na centúria oitocentista, a sátira ...
Tópico(s): Cultural, Media, and Literary Studies
2017 - University of North Carolina at Chapel Hill | Hispanófila/Hispanófila