Suzanne Verstappen, Jos N. Hoes, E. J. ter Borg, J. W. J. Bijlsma, A. A. M. Blaauw, G A van Albada-Kuipers, C van Booma-Frankfort, J. W. G. Jacobs,
To investigate the prevalence and prognostic factors of joint surgery in a large cohort of patients with rheumatoid arthritis, whose treatment, clinical and radiographic data have been assessed at predefined points in time since disease onset.Data on surgical interventions were retrospectively obtained from 482 patients with rheumatoid arthritis whose follow-up data for at least 2 years were available, including treatment and response to treatment during the first 2 years. Survival time until the ...
Tópico(s): Spondyloarthritis Studies and Treatments
2006 - BMJ | Annals of the Rheumatic Diseases
Yanxia Zhang, Aalt D. J. van Dijk, Adrian Scaffidi, Gavin R. Flematti, Manuel Hofmann, Tatsiana Charnikhova, Francel Verstappen, Jo Hepworth, Sander van der Krol, Ottoline Leyser, Steven M. Smith, B. Zwanenburg, Salim Al‐Babili, Carolien Ruyter‐Spira, Harro J. Bouwmeester,
Tópico(s): Plant Diversity and Evolution
2014 - Nature Portfolio | Nature Chemical Biology
Bert Vleeming, Barbra Heskamp, H. Bakker, Leon Verstappen, Jo Finders, Jan Stoeten, Rainer Boerret, Oliver Roempp,
It is widely expected that 193 nm lithography will be the technology of choice for volume production of the 0.10 micrometer device generation. For this purpose the PAS5500/1100 TM Step & Scan system, the second generation ArF tool, was developed. It is based on the PAS5500/900 TM , the body of which has been adapted to fit the new 0.75 NA Starlith TM projection optics. This high NA enables mass manufacturing of devices following the 0.10 micrometer design rule. The system features a 10 W 2 kHz ArF laser ...
Tópico(s): Nanofabrication and Lithography Techniques
2001 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Katarzyna A. Radomska, Mahdi M. Vaezirad, Koen M. Verstappen, Marc M. S. M. Wösten, Jaap A. Wagenaar, Jos P. M. van Putten,
Campylobacter jejuni is the main cause of bacterial food-borne diseases in developed countries. Chickens are the most important source of human infection. Vaccination of poultry is an attractive strategy to reduce the number of C. jejuni in the intestinal tract of chickens. We investigated the immunogenicity and protective efficacy of a recombinant C. jejuni flagellin-based subunit vaccine with intrinsic adjuvant activity. Toll-like receptor activation assays demonstrated the purity and TLR5 stimulating ( ...
Tópico(s): Viral gastroenteritis research and epidemiology
2016 - Public Library of Science | PLoS ONE
G. Verstappen, Leo A. van Grunsven, Chris W. Michiels, Tom Van de Putte, Jacob Souopgui, Jo Van Damme, Eric Bellefroid, Joël Vandekerckhove, Danny Huylebroeck,
Mutations in ZFHX1B cause Mowat–Wilson syndrome (MWS) but the precise mechanisms underlying the aberrant functions of mutant ZFHX1B proteins (also named Smad-interacting protein-1, SIP1) in patients are unknown. Using mass spectrometry analysis, we identified subunits of the NuRD corepressor complex in affinity-purified Zfhx1b complexes. We find that Zfhx1b associates with NuRD through its N-terminal domain, which contains a previously postulated NuRD interacting motif. Interestingly, this motif is ...
Tópico(s): Renal and related cancers
2008 - Oxford University Press | Human Molecular Genetics
Jos N. Hoes, Johannes W. G. Jacobs, Suzanne Verstappen, J. W. J. Bijlsma, Geert J. M. G. van der Heijden,
Objectives: To systematically analyse the literature on reported adverse events of low- to medium-dose glucocorticoids during ⩾1 month for inflammatory diseases. Methods: Data were systematically retrieved and selected from PUBMED, EMBASE and CINAHL databases (6097 hits). Results: A total of 28 studies (2382 patients) met the inclusion criteria. The risk of adverse events over all studies was 150 per 100 patient-years (95% confidence interval (CI) 132 to 169). Psychological and behavioural adverse events (eg, minor ...
Tópico(s): Adrenal Hormones and Disorders
2008 - BMJ | Annals of the Rheumatic Diseases
J. W. J. Bijlsma, Jos N. Hoes, Amalia A. van Everdingen, Suzanne Verstappen, Johannes W. G. Jacobs,
Disease modifying antirheumatic drugs (DMARDs) are drugs used in rheumatoid arthritis (RA) to control the disease and to limit joint damage and improve long-term outcome. The last decade evidence has accumulated that suggests that low dosages of glucocorticoids are indeed able to control the disease and limit the destruction. This role is especially present in early disease and in combination with other drugs. The evidence is carefully evaluated and discussed. The ultimate conclusion is that indeed ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2006 - Wiley | Annals of the New York Academy of Sciences
Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Ira Madan, Suzanne Verstappen, Regina Kunz, Carel Hulshof, Jan L. Hoving,
Objective Synthesising evidence of the effects of interventions to improve work participation among people with health problems is currently difficult due to heterogeneity in outcome measurements. A core outcome set for work participation is needed. Study design and setting Following the Core Outcome Measures in Effectiveness Trials methodology, we used a five-step approach to reach international multistakeholder consensus on a core outcome set for work participation. Five subgroups of stakeholders ...
Tópico(s): Global Health Workforce Issues
2023 - BMJ | BMJ Open
Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Joost G. Daams, Carel Hulshof, Ira Madan, Suzanne Verstappen, Marije Hagendijk, Regina Kunz, Jan L. Hoving,
To investigate how work participation outcomes in randomized controlled trials are measured internationally and across disciplines.We identified trials that reported on work participation in Medline, Embase, PsycINFO and Cochrane Central published between 2014 and 2019. Screening, selection, and data extraction were done by two authors independently. We grouped outcomes into four categories ("employment status", "absence from work", "at-work productivity loss," and "employability") and created subcategories ...
Tópico(s): Retirement, Disability, and Employment
2021 - Elsevier BV | Journal of Clinical Epidemiology
Susan M. Fernandes, Amy Verstappen, Kathy Ackerman, Elizabeth E. Adams, Cheryl Barton, Petar Breitinger, Stephen Crumb, Kirsten B. Dummer, Kana Harada, Paul Khairy, Michael J. Landzberg, Rachel Linstead-Goldsmith, Allison K. Meadows, Jo Ann Nieves, Arwa Saidi, Masato Takahashi, Jing Zhou, Sonja I. Ziniel, Roberta G. Williams,
To assess parental knowledge regarding lifelong congenital cardiac care (LLCCC).National guidelines recommend that nearly 50% of adult survivors with congenital heart disease (CHD) receive LLCCC; the number of adults who receive such care seems far less. Inadequate parental knowledge of LLCCC might contribute to care interruption.In this multicenter study, we administered a questionnaire to parents of children with moderate and complex CHD to assess knowledge of LLCCC.A total of 500 parents participated; ...
Tópico(s): Cardiac pacing and defibrillation studies
2011 - American Academy of Pediatrics | PEDIATRICS
Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Ira Madan, Suzanne Verstappen, Regina Kunz, Carel Hulshof, Jan L. Hoving,
Abstract Purpose Heterogeneity in work participation (WP) outcomes measurements hampers large scale evidence synthesis in systematic reviews of trials. In this survey we explore authors’ reasons for choosing specific WP outcomes and their measurement methods, including employment status, absence from work, at-work productivity loss, and employability. Methods We contacted authors of 260 trials and 69 systematic reviews and asked closed and open-ended questions about previously used WP outcomes and ...
Tópico(s): Occupational Therapy Practice and Research
2022 - Springer Science+Business Media | Journal of Occupational Rehabilitation
Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Ira Madan, Suzanne Verstappen, Regina Kunz, Carel Hulshof, Jan L. Hoving,
Abstract Background Work participation is important for health and can be considered as engagement in a major area of life which is of significance for most people, but it can also be thought of as fulfilling or discharging a role. Currently, academic research lacks a comprehensive classification of work participation outcomes. The International Classification of Functioning is the foremost model in defining work functioning and its counterpart work disability, but it does not provide a critical ( ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2022 - BioMed Central | BMC Public Health
Fabrizio De Benedetti, Jordi Antón, M. Gattorno, Helen Lachmann, I. Kone-Paut, Seza Özen, Joost Frenkel, A. Simon, Andrew Zeft, E. Ben-Chetrit, Hal M. Hoffman, Y. Joubert, K. Lheritier, A. Speziale, J. Guido, Roberta Caorsi, Federica Penco, Alice Grossi, Antonella Insalaco, Maria Alessio, Giovanni Conti, Federico Marchetti, Alberto Tommasini, Silvana Martino, Romina Gallizzi, Annalisa Salis, Francesca Schena, Francesco Caroli, Alberto Martini, Gianluca Damonte, Isabella Ceccherini, Marco Gattorno, Marie‐Louise Frémond, Carolina Uggenti, Lien Van Eyck, Isabelle Melki, Darragh Duffy, Vincent Bondet, Yoann Rose, Bénédicte Neven, Yanick J. Crow, Mathieu P. Rodero, Yvonne Kusche, Johannes Roth, Katarzyna Barczyk‐Kahlert, Giovanna Ferrara, Annalisa Chiocchetti, Silvio Polizzi, Josef Vuch, Diego Vozzi, Anna Mondino, Erica Valencic, Serena Pastore, Andrea Taddio, Flavio Faletra, Umberto Dianzani, Ugo Ramenghi, Alberto Tommasini, Qing Zhou, Xiaomin Yu, Erkan Demirkaya, Natalie Deuitch, Deborah L. Stone, Wanxia Li Tsai, Amanda K. Ombrello, Tina Romeo, Elaine F. Remmers, JaeJin Chae, Massimo Gadina, Steven B. Welch, Seza Özen, Rezan Topaloğlu, Mario Abinun, Daniel L. Kastner, Ivona Aksentijevich, Donatella Vairo, Rosalba Monica Ferraro, Giulia Zani, Jessica Galli, Micaela De Simone, Marco Cattalini, Elisa Fazzi, Silvia Giliani, Ebun Omoyinmi, Ariane Standing, Dorota Rowczenio, Annette Keylock, Sónia Gomes, Fiona Price-Kuehne, Sira Nanthapisal, Claire Murphy, Thomas Cullup, Lucy Jenkins, Kimberly Gilmour, Despina Eleftheriou, Helen Lachmann, Philip N. Hawkins, Nigel Klein, Paul Brogan, Anita Dhanrajani, Mercedes Chan, Stephanie Pau, Janet Ellsworth, Jaime Guzmán, Florence A. Aeschlimann, Marinka Twilt, Simon Eng, Shehla Sheikh, Ronald M. Laxer, Diane Hébert, Damien Noone, Christian Pagnoux, Susanne M. Benseler, Rae S. M. Yeung, Christoph Kessel, Katrin Lippitz, Toni Weinhage, Claas Hinze, Helmut Wittkowski, Dirk Holzinger, N.G. Grün, Dirk Föll, Pieter van Dijkhuizen, Federica Del Chierico, Clara Malattia, Alessandra Russo, Denise Pires Marafon, Nienke M. ter Haar, Silvia Magni‐Manzoni, Sebastiaan J. Vastert, Bruno Dallapiccola, Berent Prakken, Alberto Martini, Fabrizio De Benedetti, Lorenza Putignani, Berna Eren Fidancı, Kenan Barut, Serap Arıcı, Doğan ŞİMŞEK, Mustafa Çakan, Ezgi Deniz Batu, Sezgin Şahin, Ayşenur Kısaarslan, Ebru Yılmaz, Özge Başaran, Ferhat Demir, Kubra Ozturk, Zübeyde Gunduz, Betül Sözeri, Balahan Makay, Nuray Aktay Ayaz, Önder Yavaşcan, Özlem Aydoğ, Yelda Bilginer, Zelal Ekinci, Dilek Yıldız, Faysal Gök, Müferret Ergüven, Erbil Unsal, Özgür Kasapçopur, Seza Özen, Erkan Demirkaya, Hafize Emine Sönmez, Ezgi Deniz Batu, Betül Sözeri, Yonatan Butbul, Yelda Bilginer, Seza Özen, Claudia Bracaglia, Giusi Prencipe, Manuela Pardeo, G Lapeyre, Emiliano Marasco, Antonella Insalaco, Walter G. Ferlin, Robert D. Nelson, Cristina de Min, Fabrizio De Benedetti, Nicolino Ruperto, Hermine I. Brunner, Pierre Quartier, T. Constantin, E. Alexeeva, Isabelle Koné‐Paut, K. Marzan, Nico Wulffraat, R. Schneider, Shai Padeh, V. Chasnyk, C. Wouters, J. B. Kuemmerle‐Deschner, T. Kallinich, Bernard Lauwerys, E. Haddad, E. Nasonov, M. Trachana, Olga Vougiouka, K. Leon, E. Vritzali, K. Lheritier, Alberto Martini, Daniel J. Lovell, Francesca Schena, Stefano Volpi, Roberta Caorsi, Federica Penco, Claudia Pastorino, Francesca Kalli, Alessia Omenetti, Sabrina Chiesa, Arinna Bertoni, Paolo Picco, Gilberto Filaci, Ivona Aksentijevich, Alice Grossi, Isabella Ceccherini, Alberto Martini, Elisabetta Traggiai, Marco Gattorno, Isabelle Melki, Yoann Rose, Carolina Uggenti, Marie‐Louise Frémond, Lien Van Eyck, Naoki Kitabayashi, Marco Gattorno, Stefano Volpi, Oliviero Sacco, Isabelle Meyts, Marie‐Anne Morren, Carine Wouters, Eric Legius, Isabelle Callebaut, Christine Bodemer, Frédéric Rieux‐Laucat, Mathieu P. Rodero, Yanick J. Crow, Marie‐Louise Frémond, Mathieu P. Rodero, Nadia Jeremiah, Alexandre Bélot, Éric Jeziorski, Darragh Duffy, D. Bessis, Guilhem Cros, Gillian Rice, Bruno Charbit, Anne Hulin, Nihel Khoudour, Consuelo Modesto Caballero, Christine Bodemer, Monique Fabrè, Laureline Berteloot, Muriel Le Bourgeois, Philippe Reix, Thierry Walzer, Despina Moshous, Stéphane Blanche, Alain Fischer, Brigitte Bader‐Meunier, Frédéric Rieux‐Laucat, Yanick J. Crow, Bénédicte Neven, Kim V. Annink, Nienke M. ter Haar, Sulaiman M. Al‐Mayouf, Gayane Amaryan, Jordi Antón, KS Barron, Susanne M. Benseler, Paul Brogan, L. Cantarini, Marco Cattalini, Alexis Virgil Cochino, Fabrizio De Benedetti, F. Dedeoglu, A. De Jesus, O. Dellacasa, Erkan Demirkaya, Pavla Doležalová, K. Durrant, Fabio Gavarini, Romina Gallizzi, Raphaela Goldbach‐Mansky, E. Hachulla, Véronique Hentgen, Troels Herlin, M. Hofer, H. Hoffman, Antonella Insalaco, Annette Jansson, T. Kallinich, Isabelle Koné‐Paut, Anastasiia Kozlova, Jasmin Kuemmerle‐Deschner, Helen Lachmann,
Introduction: Gain-of-function mutations in TMEM173 encoding STING (Stimulator of Interferon Genes) underlie a novel type I interferonopathy, minimally responsive to conventional immunosuppressive therapies and associated with high childhood morbidity and mortality.A newly emerging treatment strategy in STING-related inflammation aims to control interferon (IFN) signalling post-binding of the IFN receptor, by targeting JAK1/2.We hypothesized that inhibition of IFN production itself might represent ...
BioMed Central
... J, Schoonheim-Klein M, Suvan J, Ulbricht S, Verstappen P, Walter C, Warnakulasuriya S, Wennström J, Wickholm ...
Tópico(s): Oral and Maxillofacial Pathology
2011 - Wiley | Periodontology 2000
Jan L. Hoving, Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Regina Kunz, Suzanne Verstappen, Ira Madan, Joost G. Daams, Carel Hulshof,
Tópico(s): Workplace Health and Well-being
2022 - Elsevier BV | Safety and Health at Work
Margarita Ravinskaya, Jos Verbeek, Miranda Langendam, Regina Kunz, Suzanne Verstappen, Ira Madan, Carel Hulshof, Jan L. Hoving,
Tópico(s): Workplace Health and Well-being
2022 - Elsevier BV | Safety and Health at Work
Sarah Karrar, Shiwen Xu, Joanne Nikotorowicz-Buniak, David Abraham, CP Denton, Richard Stratton, Rachel Bayley, K. A. Kite, E Clay, J. P. Smith, George D. Kitas, C Buckley, Stephen P. Young, Lin Ye, Lei Zhang, Jane Goodall, Hill Gaston, Hui Xu, Pamela Lutalo, Yin Zhao, LeeMeng Choong, Shirish Sangle, Jo Spencer, D. D’Cruz, Oliwia Ryśnik, Kieran McHugh, Paul Bowness, L. Rump-Goodrich, Derek L. Mattey, Oksana Kehoe, Jennifer T Middleton, Anton Cartwright, Caroline Schmutz, A. Askari, Jennifer T Middleton, Dianne Gardner, Louisa Jeffery, Karim Raza, David M. Sansom, E Clay, Rachel Bayley, Myra Fitzpatrick, Gordon G. Wallace, Stephen P. Young, Jacqueline Shaw, Hisanori Hatano, Alberto Cauli, Joanna L. Giles, Kieran McHugh, Alessandro Mathieu, Paul Bowness, Simon Kollnberger, Sha Webster, Lou Ellis, Louise O’Brien, Tim J. Fitzmaurice, Hill Gaston, Jane Goodall, Abdul Nazeer Moideen, Laura Evans, L. Osgood, Amanda C de C Williams, Simon Jones, Christine Thomas, Vicki O’Donnell, Mari A. Nowell, Lylia Ouboussad, Sinisa Savic, LJ Dickie, J. Hintze, Charis Wong, Gayle Cook, MH Buch, Paul Emery, Michael McDermott, Sarah Hardcastle, Celia L. Gregson, Kevin Deere, George Davey Smith, P. Dieppe, Jonathan H. Tobias, Elaine Dennison, Mark H. Edwards, J. Bennett, David Coggon, K. T. Palmer, Cary L. Cooper, Daniel F. McWilliams, April M. Young, Patrick Kiely, David A. Walsh, H. J. Taylor, IJ Harding, John N. Hutchinson, Ian Nelson, Anna M. Blom, Jonathan H. Tobias, Edward A. Clark, Joel S. Parker, M. Bukhari, Daniel F. McWilliams, Keeranur Jayakumar, April M. Young, Patrick Kiely, David A. Walsh, Janet Diffin, Mark Lunt, Tarnya Marshall, J. Chipping, Deborah Symmons, Suzanne Verstappen, H. J. Taylor, IJ Harding, John N. Hutchinson, Ian Nelson, Jonathan H. Tobias, Edward A. Clark, James Bluett, John Bowes, Peter Ho, N. McHugh, D. Buden, Oliver FitzGerald, Anne Barton, John R. Glossop, Nicola B Nixon, Richard D. Emes, P. T. Dawes, William E. Farrell, Derek L. Mattey, Ian C. Scott, Sophia Steer, Seth Seegobin, A. M. Hinks, Stephen Eyre, Ann W. Morgan, Anthony G. Wilson, L. Hocking, P. Wordsworth, Anne Barton, Jane Worthington, Andrew P. Cope, Cathryn M. Lewis, Sandra G. Guerra, Billow A. Ahmed, C. Denton, David Abraham, Carmen Fonseca, James P. Robinson, Julian Taylor, Lubna Rashid, Edward Flynn, Stephen Eyre, Jane Worthington, Anne Barton, J. Isaacs, John Bowes, Anthony G. Wilson, Jennifer H. Barrett, Ann W. Morgan, Belinda Kingston, M. Ahmed, John Kirwan, R. Marshall, Kathryn Chapman, Robert Pearson, C. Heycock, C. Kelly, M. Rynne, Vadivelu Saravanan, James Hamilton, A. Saeed, Robert J. Coughlan, John J. Carey, Ziad Farah, Wilbert Matthews, Christopher G. Bell, Sharon Petford, Lisa Tibbetts, Karen Douglas, Ward A. Holden, Joanna Ledingham, M. Fletcher, Robert D. Winfield, Zane Price, K. Mackay, C. Jane Dixon, Raymond Oppong, Sue Jowett, Elaine Nicholls, David G. T. Whitehurst, Sarah J. Hill, Alison Hammond, Elaine M. Hay, Krysia Dziedzic, C Righetti, M. Lebmeier, V Manning, Michael J. Hurley, Darwin Scott, Ernest Choy, Lindsay Bearne, Elena Nikiphorou, Scott Morris, David James, Patrick Kiely, David A. Walsh, April M. Young, Edward C.C. Wong, Julie A. Long, Anne Fletcher, M. Fletcher, S. Holmes, Peter Hockey, M. Abbas, C. Chattopadhyay, Jonathan Flint, Mary Gayed, Karin Schreiber, S. Arthanari, M. Nisar, M. Khamashta, Caroline Gordon, Ian Giles, Joanna Robson, A. Kiran, J. Maskell, Nigel Arden, Andrew Hutchings, A Emin, David Culliford, Bhaskar Dasgupta, William L. Hamilton, Raashid Luqmani, Hannah Jethwa, DM Rowczenio, Hadija Trojer, Tom Russell, Juergen Loeffler, Philip N. Hawkins, Helen J. Lachmann, I. Verma, Ashit Syngle, P. Krishan, Nidhi Garg, Jonathan Flint, Mary Gayed, Karin Schreiber, S. Arthanari, M. Nisar, M. Khamashta, Caroline Gordon, Ian Giles, Sarah Mcgowan, Dave T. Gerrard, Helen Krich Chinoy, William Ollier, R. G. Cooper, Janine A. Lamb, L. Taborda, P. Correia Azevedo, David Isenberg, K.M. Leyland, A. Kiran, Andrew Judge, Daniel A. Hunter, D. Hart, M K Javaid, Nigel Arden, C. Cooper, Mark H. Edwards, Anna Litwic, Anthony James, Djh Deeg, C. Cooper, Elaine Dennison, Mark H. Edwards, Anthony James, J Cushnaghan, Avan Aihie Sayer, Djh Deeg, C. Cooper, Elaine Dennison, Darshan Jagannath, C. Parsons, J Cushnaghan, C. Cooper, Mark H. Edwards, Elaine Dennison, L.A. Stoppiello, P.I. Mapp, Sadaf Ashraf, David R. Wilson, Ronald A. Hill, Brigitte E. Scammell, David A. Walsh,
Oxford University Press
Puja Mehta, Sue Holder, BA Fisher, Tonia L. Vincent, Kavitha Nadesalingam, Helen MacIver, William Shingler, Jyoti Bakshi, Sevda Hassan, David D’Cruz, Anthony K.C. Chan, Anna Litwic, F McCrae, Raghav Seth, F McCrae, Anupama Nandagudi, Elizabeth C. Jury, David Isenberg, Uma Karjigi, Anekwe Somtochukwu Paul, Frances Rees, Emma O’Dowd, W J Kinnear, Simon R. Johnson, Peter Lanyon, Jyoti Bakshi, Richard Stevens, Nehal Narayan, Christopher Marguerie, Heather A. Robinson, Lorrette Ffolkes, F.S. Worsnop, L.S. Ostlere, Patrick Kiely, Chethana Dharmapalaiah, N. Hassan, Anupama Nandagudi, A. Bharadwaj, Małgorzata Skibińska, Nagui Gendi, E. J. Davies, Mohamed Akil, Rachael Kilding, Jagdish Nair, Mary Norine Walsh, W. Edmund Farrar, R. N. Thompson, L. Borukhson, Charles McFadyen, D Singh, V. Rajagopal, Andrew M. Chan, L. Wearn Koh, Jason D. Christie, L. Croot, Mary Gayed, Benjamin Disney, Suman Singhal, K A Grindulis, Timothy D. Reynolds, K. Conway, David M. Williams, Jacquelyn A. Quin, G. Dean, Dennis Churchill, Karen Walker‐Bone, Iain Goff, G Reynolds, Matthew Grove, P. Patel, M. N. Lazarus, Federico Roncaroli, Carolyn Gabriel, Anne Kinderlerer, Elena Nikiphorou, Frances Hall, Ellen Bruce, Leanne Gray, Maria Krutikov, Surabhi Wig, Ian N Bruce, Maria Antonietta D’Agostino, Richard J. Wakefield, Hilde Berner Hammer, O. Vittecoq, M. Galeazzi, P. Balint, Emilio Filippucci, Ingrid Möller, Annamaria Iagnocco, Esperanza Naredo, Mikkel Østergaard, Corine Gaillez, W. Kerselaers, Kathy Holder, Manuela Le Bars, Millicent Stone, Frances M. K. Williams, Lisa E. Wolber, Jaro Karppinen, Juhani Määttä, Bobbye Jo Thompson, I. Atchia, Alice Lorenzi, G. Raftery, Philip Platt, Philip Platt, Arthur G. Pratt, Tom Turmezei, Graham M. Treece, Andrew H. Gee, Kenneth Poole, Priyanka Chandratre, Edward Roddy, L. H. Clarson, Jane Richardson, Samantha Hider, Christian Mallen, A. Lieberman, P. Prouse, P. Mahendran, Amanda Samarawickrama, Dennis Churchill, Karen Walker‐Bone, Faith D. Ottery, Robert A. Yood, Marsha Wolfson, Alfonso Ang, P. Riches, John Thomson, G. Nuki, Jennifer Humphreys, Suzanne Verstappen, J. Chipping, Kimme L Hyrich, Tarnya Marshall, Deborah Symmons, Maxim Roy, John Kirwan, R. W. Marshall, Faith Matcham, Ian C. Scott, Lauren Rayner, Matthew Hotopf, Gabrielle Kingsley, David L. Scott, Sophia Steer, M. H., Chanaka Dahanayake, Ian C. Scott, Gabrielle Kingsley, Andrew P. Cope, David L. Scott, Chanaka Dahanayake, M. H., Ian C. Scott, Gabrielle Kingsley, Andrew P. Cope, David L. Scott, Aaron Wernham, Laura Ward, David Carruthers, A. Deeming, Christopher D. Buckley, K. Raza, Paola de Pablo, Elena Nikiphorou, Lewis Carpenter, Keeranur Jayakumar, C. Solymossy, J. Dixey, Alexander S. Young, Animesh Singh, Henry Penn, Nicolas Ellerby, Derek L. Mattey, Jon Packham, P. T. Dawes, Samantha Hider, Nora Ng, F. Humby, Stefano Bombardieri, S. Kelly, Maria Di Cicco, Simon Dadoun, Rebecca Hands, Vidalba Rocher, B. L. Kidd, David B. Pyne, Costantino Pitzalis, S. Poore, David Hutchinson, A. Low, Mark Lunt, Louise Mercer, James Galloway, Rebecca Davies, Kerrie Watson, William G Dixon, Deborah Symmons, Kimme L Hyrich, Louise Mercer, Mark Lunt, A. Low, James Galloway, K. D. Watson, William G Dixon, Deborah Symmons, Kimme L Hyrich, A. Low, Mark Lunt, Louise Mercer, Ellen Bruce, William G Dixon, Kimme L Hyrich, Deborah Symmons, Shaista Malik, Clive Kelly, Jean Hamilton, C. Heycock, V. Saravanan, M. Rynne, H Harris, Fiona J. Tweedie, Y. Skaparis, Matthew T. White, Nicola Scott, K. Samson, C. Mercieca, Sophie Clarke, Amy J. Warner, Jennifer Humphreys, Mark Lunt, Tarnya Marshall, Deborah Symmons, Suzanne Verstappen, Emilie Chan, Clive Kelly, Felix Woodhead, Muhammad Nisar, S. Arthanari, Julie Dawson, N. Sathi, Yasmin Ahmad, Gouri Koduri, Alexander S. Young, Clive Kelly, Emilie Chan, Yasmin Ahmad, Felix Woodhead, Muhammad Nisar, S. Arthanari, Julie Dawson, N. Sathi, Gouri Koduri, Alexander S. Young, J. Cumming, P. Stannett, R G Hull, Giorgos S. Metsios, Antonios Stavropoulos‐Kalinoglou, Jet Veldhuijzen Zanten, P. Nightingale, Yiannis Koutedakis, George D. Kitas, Elena Nikiphorou, J. Dixey, Paul Williams, Patrick Kiely, David A. Walsh, Lewis Carpenter, Alexander S. Young, Elizabeth Perry, Clive Kelly, Anthony De Soyza, Tom J. Moullaali, P. Eggleton, David Hutchinson, Jet Veldhuijzen Zanten, Giorgos S. Metsios, Antonios Stavropoulos‐Kalinoglou, Aamer Sandoo, George D. Kitas, Paola de Pablo, Fiona Maggs, David Carruthers, Abdul Faizal, Mark T Pugh, Paresh Jobanputra, Oksana Kehoe, Anton Cartwright, A. Askari, A El Haj, Jim Middleton, Sarah Aynsley, J Hardy,
Background: Thoracic aortic aneurysms (TAA) and dissections are not uncommon causes of sudden death in young adults. Loeys-Dietz syndrome (LDS) is a rare, recently described, autosomal dominant, connective tissue disease characterized by aggressive arterial aneurysms, resulting from mutations in the transforming growth factor beta (TGFβ) receptor genes TGFBR1 and TGFBR2. Mean age at death is 26.1 years, most often due to aortic dissection. We report an unusually late presentation of LDS, diagnosed ...
Oxford University Press
G. J. Navis, Geert Jan Sterk, J. W. van Nispen, M Hichens, Alexandra Sauter, H. Lingeman, C. M. B. van den Beld, U.R. Tjaden, J. van der Greef, Dominic M. Desiderio, D. C. Cubbins, C. McMartin, R. L. Webb, Lawrence P. Wennogle, H. E. Wysowskyi, M. B. Zimmerman, Vincent H. L. Lee, J. Sandow, H. Seidel, R. Schmiedel, Bradley T. Keller, Kevin R. Smith, Ronald T. Borchardt, W. A. Banks, Abba J. Kastin, D. de Wied, Patrick P. DeLuca, James R. Robinson, Susanne Lundin, Hans Vilhardt, Murray Saffran, Gulshan Kumar, D. G. Neckers, Frederick E. Williams, J B Field, Rebecca Jones, L. Panepinto, A. S. Harris, Alan C. Moses, Shozo Muranishi, Harry E. Boddé, Maria Ponec, John Verhoef, Gary G. Liversidge, Gerard J. Boer, J. Kruisbrink, H. de Nijs, T. R. M. Bouwman, M. J. D. Eenink, Harish M. Patel, H. Bundgaard, J. D. Larsen, M. N. Nielsen, Anders Buur, U. R. Tjadeh, Michel Lemaire, H. Andres, Peter Marbach, L. Widlund, O. Guilbaud, Peter Wilton, Joost B. M. M. van Bree, K. L. Audus, Johanna Deinum, Karin Norén, Morgan Sohtell, Björn Weström, Hans G. Folkesson, Börje W. Karlsson, Christiane Damgé, C. Michel, M. Aprahamian, Patrick Couvreur, F. Puisieux, Elka Touítou, Franco Alhaique, Paula Fisher, Adriana Memoli, F.M. Riccieri, E. Santucci, W. A. J. J. Hermens, S. G. Romei jn, F. W. H. H. Merkus, C Schneider, T. W. Smith, K. -D. Bremecker, K. -D. Hungerer, Y. Tabata, Y. Ikada, Kiyohiro Uno, S. Muramatsu, J. W. Bruning, F.H.J. Claas, M. J. Kardol, J. M. van Ree, C. J. J. Rust, W. Verduyn, V. M. Wiegant, G. Wolterink, Ewoud J. van Hoogdalem, C. D. Heijligers-Feijen, Albertus G. de Boer, D. D. Breimer, C. B. Lambalk, H. van Kessel, J. de Koning, J. A. M. J. van Dieten, G. P. van Rees, J. Schoemaker, J. -Ph. Devissaguet, K. Orieu, F. Dray, Éric Ezan, J.evissaguet, K. Drieu, Patricia L. Dray, E. Ezah, D. J. Barnfield, Y. K. Barker, Simon Knott, G. S. Miles, A. Warrander, Hugh K. Adam, Y. Barker, F Hutchinson, R. Milsted, R. H. Moore, Alan Swaisland, Y. Barke, E. T. Porter, Bob Holmes, Marie Barnard, Jos H. Beijnen, S. C. H. Lubbers, O.A.G.J. van der Houwen, M. W. Lobbezoo, W.J.M. Underberg, Th. Cachet, E. Roets, Jos Hoogmartens, H. Vanderhaeghe, H. de Bree, D. J. K. van der Stel, O. A. M. Brockhoff, M. P. van Berkel, K. Sierat, Gerard de Groot, B. C. A. Tepas, Onno E. de Noord, J. Hempenius, P.M.J. Coenegracht, J. H. G. Jonkman, D.A. Doornbos, J.A. De Schutter, P. De Moerloose, L. P. C. Delbressine, F. M. Kaspersen, Arjan Blokland, Alexander L. L. Duchateau, T. A. Verstappen, P. J. H. Hendricks, F. Elferink, Oscar Leeuwenkamp, H. M. Pinedo, W. J. F. vd Vijgh, K. Ensing, D. A. Bloemhof, W. G. in 't Hout, Dick de Zeeuw, Karla G. Feitsma, Ben F. H. Drenth, Dick de Zeeuw, T. K. Gerding, Ben F. H. Drenth, A. S. Horn, C. Groen, J. Tipker, J. K. van den Bergh-Swart, F. J. Spruit, J. H. M. van den Berg, E. H. Groot Bramel, Otto Bekers, Masaki Otagiri, P. S. L. Janssen, J. W. van Nispen, P. A. T. A. Melgers, M. J. M. v. Zeeland, R. L. A. E. Hamelinck, B. C. Goverde, G. W. M. v. Aalst, P.R. Kootstra, H. H. van den Broek, Elbert A. Hogendoorn, C. E. Goewie, P.J.M. Kwakman, U.A.Th. Brinkman, R. W. Frei, G. J. de Jong, N. Lammers, N. Lammers, H. M. Ruijten, J. de Jong, P. A. Maessen, K. Mross, H. M. Plnedo, W. J. F. van der Vljgh, Naeem Hasan Khan, Jos Hoogmartens, S. V. Rose, L. G. D. Lammerts van Bueren, P. H. van Amsterdam, H. van Beek, A.J. Baars, Leendert A. van Ginkel, H. M. Steinbuch, H.J. van Rossum, H. van Blitterswijk, P.W. Zoontjes, E. van der Heeft, A. J. P. M. de Jong, R. W. Stephany, R. van Gijn, J. J. M. de Clippeleir, S. L. Verweij, A. C. A. Paalman, M.A.J. van Opstal, P. Krabbenborg, J.J.M. Holthuis, W.P. van Bennekom, A. Bult, Frank A. Redegeld, E. Houdkamp, C. van de Water, N. Haagsma, D. J. K. van der Stel, D.E.M.M. Vendrig, A. Mekking, J. Teeuwsen,
Tópico(s): Histone Deacetylase Inhibitors Research
1988 - Springer Nature | Pharmaceutisch Weekblad
M. Barnard, Jos H. Beijnen, Samuel Lubbers, O.A.G.J. van der Houwen, M. W. Lobbezoo, W.J.M. Underberg, Th. Cachet, E. Roets, J. Hoogmartens, H. Vanderhaeghe, H. de Bree, D. J. K. van der Stel, O. A. M. Brockhoff, M. P. van Berkel, K. Sierat, G. de Groot, B. C. A. Tepas, Onno E. de Noord, J. Hempenius, P.M.J. Coenegracht, J. H. G. Jonkman, D. A. Doornbos, J.A. De Schutter, P. De Moerloose, L. P. C. Delbressine, F. M. Kaspersen, A. Blokland, Alexander L. L. Duchateau, T. A. Verstappen, P. J. H. Hendricks, F. Elferink, Oscar Leeuwenkamp, Herbert M. Pinedo, W. J. F. vd Vijh, K. Ensing, D. A. Bloemhof, W. G. in 't Hout, Dick de Zeeuw, Karla G. Feitsma, Ben F. H. Drenth, Dick de Zeeuw, T. K. Gerding, Ben F. H. Drenth, Dick de Zeeuw, A. S. Horn, Cornelis Petrus Groen, J. Tipker, J. K. van den Bergh-Swart, F. J. Spruit, J. H. N. van den Berg, E. H. Groot Bramel, Jos H. Beijnen, O. Beckers, M. Otagiri, W.J.M. Underberg, P. S. L. Janssen, J. W. van Nispen, P. A. T. A. Melgers, M. J. M. v. Zeeland, R. L. A. E. Hanmelinck, B. C. Goverde, G. W. M. v. Aalst, P.R. Kootstra, H. H. van den Broek, Elbert A. Hogendoorn, C. E. Goewie, P.J.M. Kwakman, U.A.Th. Brinkman, R.W. Frei, G. J. de Jong, F. J. Spruit, N. Lammers, J. H. M. van den Berg, N. Lammers, Cornelis Petrus Groen, H. M. Ruijten, P. A. Maessen, K. B. Mross, Herbert M. Pinedo, W. J. F. van der Vijgh, Naeem Hasan Khan, J. Hoogmartens, E. Roets, H. Vanderhaeghe, S. V. Rose, L. G. D. Lammerts van Bueren, H. van Beek, A.J. Baars, Leendert A. van Ginkel, H. M. Steinbuch, H.J. van Rossum, H. van Blitterswijk, P.W. Zoontjes, E. van der Heeft, A. J. P. M. de Jong, R. W. Stephany, R. van Gijn, J. J. M. de Clippeleir, Jos H. Beijnen, W.J.M. Underberg, S. L. Verweij, A. C. A. Paalman, M.A.J. van Opstal, P. Krabbenborg, J.J.M. Holthuis, W.P. van Bennekom, A. Bult, C. van de Water, N. Haagsma, D. J. K. van der Stel, H. de Bree, O. A. M. Brockhoff, D.E.M.M. Vendrig, A. Mekking, J. Teeuwsen, J.J.M. Holthuis,
Tópico(s): Biochemical effects in animals
1988 - Springer Nature | Pharmaceutisch Weekblad
Mariëtte T. Ackermans, Erik Endert, J. Aluoch, I. Ouintens, E. Roets, Jos Hoogmartens, G. Barka, C. Opper, H. Kerkdijk, Dirk T. Witte, Fieke Bruggeman, Jan Piet Franke, Swier Copinga, Joke Jansen, Dick de Zeeuw, Ingrid J. Bosman, K. Ensing, Ige Dekker, Ir. A. B. J. M. Dams, C. M. J. De Pooter, Anne Marie J. Fichtinger-Schepman, Pierre Scalliet, R. A. A. Maes, Felicity Berends, A.T. van Oosterom, E. A. Bruijn, L. A. Fay, C. J. Verstappen, W. Pluijms, H. Irth, A. J. Oosterkamp, W. Welle, Kasim Khan, J. Paesen, P. L. Jacobs, Marcel P. de Vries, Norbert Lammers, Frans Biermans, Eric Witte, P. Mussche, M.H. Lamoree, N.J. Reinhoud, U.R. Tjaden, W.M.A. Niessen, J. van der Greef, A. Solie, Aran Paulus, Antje Klockow, Gerard Bruin, Léon Reubsaet, Jos H. Beijnen, A. Bult, J. Teeuwsen, Emily Koster, Joop C. M. Waterval, W.J.M. Underberg, W. Cypers, P. Claeys, Michael H. Simonian, H.A.H. Rongen, Helma M. Horst, A. Bult, W.P. van Bennekom, J. Šmisterová, G.N. Thoithi, Ann Van Schepdael, Karel Wouters, Piet Herdewijn, D.E.M.M. Vendrig, E. Gout, P. M. J. Santvoort, R. L. A. E. Hamelinck, M. J. M. v. Zeeland, P. S. L. Janssen, R.J.M. Vervoort, M. W. J. Derksen, F.A. Maris, Yongxin Zhu, C. Hendrix, R. BUSSON, G. Janssen,
Tópico(s): Science, Research, and Medicine
1994 - Springer Science+Business Media | Pharmacy World & Science
David Tovey, Peter Commentaries, Ralph I. Horwitz, Gabriella Lobitz, McKayla Mawn, Allison Hayes‐Conroy, Mark R. Cullen, Ida Sim, Burton H. Singer, Nathan Ford, Rebekah Thomas, John W. Grove, Rafael Leite Pacheco, Ana Lúiza, Cabrera Martimbianco, Rachel Riera, Liam Mccoy, Connor T. A. Brenna, Stacy S. Chen, Karina Vold, Sunit Das, H Leufkens, Tim Morris, Maarten van Smeden, Jean Digitale, Jeffrey Martin, M. Maria Glymour, Carlos A. Cuello‐García, Nancy Santesso, Rebecca Morgan, Jos Verbeek, Kris Thayer, Mohammed Ansari, Joerg J Meerpohl, Lukas Schwingshackl, Vittal Srinivasa, Jan Katikireddi, Barnaby Brozek, Mohammad Reeves, Maicon Murad, Reem Falavigna, Deborah Mustafa, E. Paul, Paul Alexander, Elie Garner, Gordon Akl, Holger Guyatt, Qi Wang, Ya Xiao, Taotao Guo, Hongfei Zhu, Jieyun Li, Honghao Lai, Ying Zhang, Fengwen Yang, Yu Liu, Kehu Yang, Yaolong Chen, Jinhui Tian, Guowu Ding, Long Ge, Jadbinder Seehra, Kristina Bertl, Clóvis Mariano Faggion, Nikolaos Pandis, Margarita Ravinskaya, Miranda Langendam, Joost G. Daams, Carel Hulshof, Ira Madan, Suzanne Verstappen, Marije Hagendijk, Regina Kunz, Jan W. Hoving,
Missing trials in drug regulatory dossiers may have good reasons, but should be predefined and transparent
2022 - Elsevier BV | Journal of Clinical Epidemiology
Marian T. Hannan, Leslie J. Crofford, Catherine L. Backman, Hermine I. Brunner, David Daikh, San Francisco, Robert F. DeVellis, Chapel Hill, Monique A. M. Gignac, Seoyoung C. Kim, Michael P. LaValley, Carlo A. Marra, Kaleb Michaud, Pascale Schwab, Daniel K. White, Nora G. Singer, Kelli D. Allen, Cecilia P. Chung, Kim Jones, Brian L. Kotzin, Los Angeles, Janet L. Poole, Albuquerque Amr, H Sawalha, Ann Arbor, Nancy Parker, Atlanta Parry, Atlanta Hutto, Atlanta Palmer, Atlanta Fladger, Carolyn Kaut Roth, Ilana N. Ackerman, Graciela S. Alarcón, James S. Andrews, Felix Angst, Joshua F. Baker, Bonnie L. Bermas, Androniki Bili, Susan J. Blalock, Teresa J. Brady, Atlanta Burgos-Vargas, Mexico City, Vivian P. Bykerk, Pascal Claudepierre, Delphine S. Courvoisier, Lisa Criscione‐Schreiber, Randall Cron, James A. Dale, Aileen M. Davis, Joost Dekker, Christina Drenkard, A. P. Dunlop, John M. Esdaile, Elizabeth D. Ferucci, Barbara Gandek, Michael George, Jon T. Giles, New York, Yvonne M. Golightly, Shintaro Hirata, Sheree E. Hurn, Kei Ikeda, Linda Kwakkenbos, Jungwha Lee, Yvonne Lee, Linda Li, Elena Losina, Natalie McCormick, Robert R. McLean, Shannon E. Munteanu, Jingbo Niu, George Peat, Anthony V. Perruccio, Gabriela Schmajuk, Ami Shah, Julia F. Simard, Emily C. Somers, Sara K. Tedeschi, Kristina A. Theis, Atlanta Suzanne, M. Verstappen, Pamela F. Weiss, David Haag, Afton L. Hassett, Sandra Mintz, Alyssa B. Dufour, Adam P. Goode, Marie Westby, Janet Stevens, Elizabeth A. Schlenk, Hazel Breland, Susan Richmond, Invited Guest, Christine Stamatos, Great Neck, Edward Herzig, Eric T. Hsieh, Nortin M. Hadler, Richard S. Panush, Calvin R. Brown, Kenneth S. O’Rourke, Howard A. Fuchs, Chaim Putterman, Irene Tan, Joanne Valeriano‐Marcet, Evelyn Hsieh, Sarah Zirkle, Marcy Rheumatoid, Harlan Sayles, Debra Bergman, Grant W. Cannon, Ted R. Mikuls, Jennifer L. Barton, Philip Hamann, Richard Holland, Kimme L Hyrich, John D Pauling, Gavin Shaddick, Alison Nightingale, Neil McHugh, Melanie Rohr, Stanley Cohen, J. Carter Thorne, James R. O’Dell, Ayako Hirata, Takehisa Ogura, Norihide Hayashi, Sayaka Takenaka, Hideki Ito, Kennosuke Mizushina, Yuki Fujisawa, Naoko Yamashita, Sumie Nakahashi, M. Imamura, Rie Kujime, Hideto Kameda, Mari€ Ette De Rooij, M. van der Leeden, John Cheung, M. van der Esch, Arja H€ Akkinen, Dani€ El Haverkamp, Leo D. Roorda, Jos W. R. Twisk,
Arthritis Care & ResearchVolume 69, Issue 6 Issue InformationFree Access Issue Information First published: 29 May 2017 https://doi.org/10.1002/acr.23050AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link ...
Tópico(s): Osteoarthritis Treatment and Mechanisms
2017 - Wiley | Arthritis Care & Research
Sarah Kathleen Heathfield, Ben Parker, Leo Zeef, Ian N Bruce, M. Yvonne Alexander, Fraser L. Collins, Megan Stone, Emily Wang, Anwen S. Williams, Helen L. Wright, H Thomas, Robert J. Moots, Steven W. Edwards, Chevelle Bullock, V. Chapman, David A. Walsh, Ali Mobasheri, Dave Kendal, Sally Kelly, Rachel Bayley, Christopher D. Buckley, Stephen P. Young, L. Rump-Goodrich, Jim Middleton, Linkao Chen, Robin Fisher, Simon Kollnberger, Nilabh Shastri, Benedikt M. Kessler, Paul Bowness, Abdul Nazeer Moideen, Laura Evans, L. Osgood, Anwen S. Williams, Simon A. Jones, M. A. Nowell, Y. Mahadik, Stephen P. Young, M. D. Morgan, Caroline Gordon, Lorraine Harper, Joanna L. Giles, B. Paul Morgan, Claire L. Harris, Oliwia Ryśnik, Kirk M. McHugh, Simon Kollnberger, Sravan Payeli, Oscar C. Marroquin, Jacqueline Shaw, C Renner, Paul Bowness, Saba Nayar, Thomas Cloake, Stefano Bombardieri, Costantino Pitzalis, Christopher D. Buckley, Francesca Barone, Francesca Barone, Saba Nayar, Thomas Cloake, Pat Lane, M C Coles, Christopher D. Buckley, Emma L. Williams, Christopher J Edwards, Cary L. Cooper, Richard O. C. Oreffo, Sara Dunn, Aileen Crawford, Mark Wilkinson, Christine L. Le Maitre, R.A.D. Bunning, J. Daniels, K. L. E. Phillips, N. Chiverton, Christine L. Le Maitre, Simon Kollnberger, Jacqueline Shaw, Anne J. Ridley, Isabel Wong‐Baeza, Kirk M. McHugh, Sarah Keidel, Antoni Chan, Paul Bowness, Nicola Gullick, Hanan Sayed M. Abozaid, David M. Jayaraj, Hayley G. Evans, Darwin Scott, Ernest Choy, Leonie S. Taams, Maela Hickling, Georg Golor, A. Jullion, S. Shaw, Kosmas Kretsos, Shahla Bari, Brian Rhys-Dillon, N. Amos, Stefan Siebert, K. L. E. Phillips, N. Chiverton, R. D. Bunning, G. Haddock, Alison K. Cross, Christine L. Le Maitre, I. L. ten Kate, Emma Phillips, Alison K. Cross, N. Chiverton, G. Haddock, R.A.D. Bunning, Christine L. Le Maitre, Sabrina Ceeraz, Jo Spencer, E. Choy, Valerie Corrigall, Anne Crilly, H. P. Palmer, John C. Lockhart, Robin Plevin, William R. Ferrell, Iain B. McInnes, David Hutchinson, L. A. Perry, Maria DiCicco, F. Humby, Sally Kelly, Rebecca Hands, Christopher D. Buckley, Iain B. McInnes, Peter C. Taylor, Stefano Bombardieri, Costantino Pitzalis, Puja Mehta, Alison Mitchell, Carolyn Tysoe, Richard Caswell, Martina Owens, T. Vincent, Tahir Hashmi, Alec Price-Forbes, Christopher Sharp, Hedwig S. Murphy, E. F. Wood, Teresa Doherty, Julie Sheldon, Nidhi Sofat, Iain Goff, Philip Platt, Rizwan Suliankatchi Abdulkader, Gavin Clunie, Mediola Ismajli, Elena Nikiphorou, Adam Young, Nicola Tugnet, J. Dixey, Samudra Prosad Banik, David Alcorn, John Hunter, Win Win Maw, Pradnya D. Patil, Finbarr Hayes, Way Main Wong, Frances Borg, Bhaskar DasGupta, A. P. Malaviya, A. J. Ostor, Jasroop Chana, Ashfaq Ahmed, Sally Edmonds, Finbarr Hayes, Lucy Coward, Frances Borg, Jennifer Heaney, Nicole Amft, J. Simpson, V. S. Dhillon, Yezenash Ayalew, F. Khattak, Mary Gayed, Roshan Amarasena, Frank McKenna, Roshan Amarasena, Frank McKenna, M. Mc Laughlin, K Baburaj, Zozik Fattah, Nora Ng, Joanna B. Wilson, B. Colaco, M. Williams, Tochukwu Adizie, Bhaskar DasGupta, Michelle Casey, Stefanie Lip, Siao Pei Tan, David Anderson, Calum Robertson, I. Devanny, Michael Field, Douglas G. Walker, Sandra Robinson, Sarah Ryan, Andrew Hassell, Joyce Bateman, Maggie Allen, Derek Davies, Claire Cowen Crouch, Karen Walker‐Bone, Nicola Gainsborough, Nicola Gullick, Pamela Lutalo, Usa Davies, Karen Walker‐Bone, J. R. Mckew, Andrena Millar, Stephen Wright, A. L. Bell, M. Thapper, Trianthi Roussou, J. CUMMING, R G Hull, M. Thapper, Trianthi Roussou, John McKeogh, M. B. O’Connor, A. I. Hassan, Ursula Bond, John M. Swan, Mark J. Phelan, David Coady, Neil G. Kumar, Luke Farrow, Marwan Bukhari, Alexander Oldroyd, C. Greenbank, John McBeth, Robert J. Duncan, Deborah Brown, M.A. Horan, Neil Pendleton, Alastair Littlewood, Lis Cordingley, M. R. Mulvey, Elizabeth M. Curtis, Zoe Cole, Sarah Crozier, N. Georgia, Sandra Robinson, Keith M. Godfrey, Avan Aihie Sayer, Hazel Inskip, Cary L. Cooper, Nicholas C. Harvey, Rebecca Davies, Louise Mercer, James Galloway, Andrea Low, K. Watson, Mark Lunt, Deborah Symmons, Kimme L Hyrich, Sarang Chitale, C. Estrach, Robert J. Moots, Nicola Goodson, E.C.C. Rankin, C Q Jiang, Kun-Ching Cheng, TH Lam, Peymané Adab, Stephanie Ling, Sarang Chitale, Robert J. Moots, C. Estrach, Nicola Goodson, Jennifer Humphreys, C.J. Ellis, Diane Bunn, Suzanne Verstappen, Deborah Symmons, E. Fluess, Gary J. Macfarlane, Christine Bond, Gareth T. Jones, Ian C. Scott, S. Steer, Cathryn M. Lewis, Andrew P. Cope, M. R. Mulvey, Gary J. Macfarlane, Deborah Symmons, Karina Lovell, Philip Keeley,
Background: Cardiovascular disease is a major comorbidity of rheumatoid arthritis (RA) and a leading cause of death. Chronic systemic inflammation involving tumour necrosis factor alpha (TNF) could contribute to endothelial activation and atherogenesis. A number of anti-TNF therapies are in current use for the treatment of RA, including certolizumab pegol (CZP), (Cimzia ®; UCB, Belgium). Anti-TNF therapy has been associated with reduced clinical cardiovascular disease risk and ameliorated vascular function ...
Oxford University Press