Héctor Rudilla, Alexandra Merlos, Eulàlia Sans-Serramitjana, Ester Fusté, Josep M. Sierra, Antonio Zalacain, Teresa Vinuesa, Miguel Viñas,
The emergence of antimicrobial resistance due to the overuse of antimicrobials together with the existence of naturally untreatable infections well demonstrates the need for new instruments to fight microbes. Antimicrobial peptides (AMPs) are a promising family of molecules in this regard, because they abundantly occur in nature and the results of preliminary studies of their clinical potential have been encouraging. However, further progress will benefit from the standardization of research methods ...
Tópico(s): Antimicrobial agents and applications
2018 - AIMS Press | AIMS Microbiology
Patricia Pereiro, Pablo Balseiro, Alex Romero, S. Dios, Gabriel Forn‐Cuní, Berta Fusté, Josep V. Planas, Sergi Beltrán, Beatriz Novoa, António Figueras,
Background Turbot (Scophthalmus maximus L.) is an important aquacultural resource both in Europe and Asia. However, there is little information on gene sequences available in public databases. Currently, one of the main problems affecting the culture of this flatfish is mortality due to several pathogens, especially viral diseases which are not treatable. In order to identify new genes involved in immune defense, we conducted 454-pyrosequencing of the turbot transcriptome after different immune stimulations. ...
Tópico(s): Antimicrobial Peptides and Activities
2012 - Public Library of Science | PLoS ONE
Manuel Yúfera, Silke Halm, Sergi Beltrán, Berta Fusté, Josep V. Planas, Gonzalo Martínez‐Rodríguez,
Gilthead seabream (Sparus aurata) is a teleost belonging to the family Sparidae with a high economical relevance in the Mediterranean countries. Although genomic tools have been developed in this species in order to investigate its physiology at the molecular level and consequently its culture, genomic information on post-embryonic development is still scarce. In this study, we have investigated the transcriptome of a marine teleost during the larval stage (from hatching to 60 days after hatching) ...
Tópico(s): Aquaculture Nutrition and Growth
2011 - Springer Science+Business Media | Marine Biotechnology
Rosa Gassió, M. Antònia Vilaseca, Nilo Lambruschini, C Boix, María E. Fusté, Josep M. Campistol,
Cognitive functions were assessed in 9 patients with mild to moderate phenylketonuria (PKU) ranging from 6 to 18 years of age, who were in long-term treatment (>5 years) with 5-9 mg/kg/day tetrahydrobiopterin (BH4) on compassionate use, provided by Schircks Inc. An extensive study of cognitive functions (intelligence quotient (IQ), visuospatial, visual memory, fine motor, executive and attentional functions) was conducted, and behavior was assessed using the ADHD Rating Scale and the Behavior Rating Inventory ...
Tópico(s): Diet and metabolism studies
2009 - Elsevier BV | Molecular Genetics and Metabolism
Xavier Fusté, Josep María Gili,
In October 1977 the model of general circulation of the water masses off the coast of Galicia, and the presence of a coastal upwelling, led to a high primary productivity. This high productivity in rum favoured the development of a rich population of decapod larvae. The abundance and distribution pattern of these organisms were closely linked (I) to the abundant presence of the corresponding adult species in the area, (li) with the spatial distribution of phytoplanlctonic populations concurrently ...
Tópico(s): Marine Bivalve and Aquaculture Studies
1991 - Oxford University Press | Journal of Plankton Research
Maria-Jesús Pueyo-Sánchez, M. Larrosa, Xavier Surís, E. Casado, Jaume Auleda, Josep Fusté, Vicente Ortún Rubio,
Objectivesto describe the secular trend and seasonal variation in the incidence of hip fracture (HF) over 12 years (2003–2014) in Catalonia, the community with the highest incidence of HF in Spain.
Tópico(s): Hip disorders and treatments
2016 - Oxford University Press | Age and Ageing
Ramón Escuriet, María Pueyo, Mercedes Pérez-Botella, Xavi Espada, Isabel Salgado, Analía Gómez, Herminia Biescas, Isabel Espiga, Joanna White, Rosa Fernández, Josep Fusté, Vicente Ortún Rubio,
In Spain, the Strategy for Assistance in Normal Childbirth (SANC) promoted a model of care, which respects the physiological birth process and discards unnecessary routine interventions, such as episiotomies. We evaluated the rate of episiotomy use and perineal trauma as indicators of how selective introduction of the SANC initiative has impacted childbirth outcomes in hospitals of Catalonia. Cross-sectional study of all singleton vaginal term deliveries without instrument registered in the Minimum ...
Tópico(s): Ureteral procedures and complications
2015 - BioMed Central | BMC Health Services Research
Josep Fusté, Elisa Séculi, Pilar Brugulat, Antònia Medina, Salvi Juncà,
Conocer las diferencias en las características socioeconómicas, el estado de salud, la utilización de servicios y la satisfacción con éstos entre la población catalana que dispone únicamente de aseguramiento sanitario público y la que tiene doble cobertura de aseguramiento. Datos de la Encuesta de Salud de Cataluña 2002 con entrevista a 8.400 personas. Entre los individuos que tenían cobertura pública de servicios sanitarios, se han diferenciado los que también tenían cobertura por entidades de ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2005 - Elsevier BV | Gaceta Sanitaria
Elisa Séculi, Josep Fusté, Pilar Brugulat, S. Juncà, Montserrat Rué, Montserrat Guillén,
Analizar las diferencias en la percepción del estado de salud de los varones y mujeres en las últimas etapas de la vida y explorar su relación con variables sociodemográficas y de salud. Datos procedentes de la Encuesta de Salud de Cataluña de 1994, de 1.459 varones y 1.993 mujeres de 60 y más años. Se realizó un análisis de la autovaloración del estado de salud según la edad, el sexo, la clase social, la declaración de enfermedades crónicas y la discapacidades y se aplicó un modelo de análisis ...
Tópico(s): Aging and Gerontology Research
2001 - Elsevier BV | Gaceta Sanitaria
To determine whether variability exists among primary care teams (PCTs) in Catalonia in opportunistic screening activities (screening for smoking, drinking, hypertension and tetanus vaccination) and to analyze the explanatory factors in the individual characteristics of the population treated and the characteristics of the PCT.A multilevel analysis with individual and PCT explanatory variables was performed. The data were draw from a sample of 3,000 clinical histories from the adult population treated ...
Tópico(s): Primary Care and Health Outcomes
2001 - Elsevier BV | Gaceta Sanitaria
Mark Benney, Everett C. Hughes,
... Rueda, Margarita Sánchez-Candamio, Jordi Sanz, Àngels Elias, Josep Fusté Incorporación de las visiones de ciudadanos, profesionales y ...
Tópico(s): Public Spaces through Art
1956 - University of Chicago Press | American Journal of Sociology
Ramón Escuriet, María Pueyo, Herminia Biescas, Cristina Colls, Isabel Espiga, Joanna White, Xavi Espada, Josep Fusté, Vicente Ortún Rubio,
Childbirth assistance in highly technological settings and existing variability in the interventions performed are cause for concern. In recent years, numerous recommendations have been made concerning the importance of the physiological process during birth. In Spain and Catalonia, work has been carried out to implement evidence-based practices for childbirth and to reduce unnecessary interventions. To identify obstetric intervention rates among all births, determine whether there are differences ...
Tópico(s): Global Maternal and Child Health
2014 - BioMed Central | BMC Pregnancy and Childbirth
Josep Fusté, Bonaventura Bólibar, Ángel Castillo, Jordi Coderch, Irene Ruano, Antoni Sicras,
Tópico(s): Medical Coding and Health Information
2002 - Elsevier BV | Atención Primaria
Lídia López-Jiménez, Ester Fusté, Blanca Martínez‐Garriga, Josep Arnabat‐Domínguez, Teresa Vinuesa, Miguel Viñas,
Microbial biofilms are involved in almost all infectious pathologies of the oral cavity. This has led to the search for novel therapies specifically aimed at biofilm elimination. In this study, we used atomic force microscopy (AFM) to visualize injuries and to determine surface roughness, as well as confocal laser scanning microscopy (CLSM) to enumerate live and dead bacterial cells, to determine the effects of photodynamic therapy (PDT) on Enterococcus faecalis biofilms. The AFM images showed that ...
Tópico(s): Legionella and Acanthamoeba research
2015 - Springer Science+Business Media | Lasers in Medical Science
Rita Fernández-Hernández, Marta Rafel, Noel P. Fusté, Rafael Aguayo Ortiz, Josep Manel Casanova, Joaquim Egea, Francisco Ferrezuelo, Eloi Garí,
The function of Cyclin D1 (CycD1) has been widely studied in the cell nucleus as a regulatory subunit of the cyclin-dependent kinases Cdk4/6 involved in the control of proliferation and development in mammals. CycD1 has been also localized in the cytoplasm, where its function nevertheless is poorly characterized. In this work we have observed that in normal skin as well as in primary cultures of human keratinocytes, cytoplasmic localization of CycD1 correlated with the degree of differentiation of ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2013 - Taylor & Francis | Cell Cycle
J. Bosch-Fusté, Montserrat Riu-Aumatell, Josep M. Guadayol, Josep Caixach, Elvira López‐Tamames, Susana Buxaderas,
Simultaneous distillation extraction (SDE) and closed-loop stripping analysis (CLSA) show great capacity for organic compound extraction. Here we used these techniques to obtain and characterize a wide range of volatile compounds from aged cava sparkling wine. We also explored the potential application of head space-solid phase micro extraction (HS-SPME) to determine the distinctive volatile compounds of aged cava as this technique is a common extraction method in quality flavour control. For SDE, ...
Tópico(s): Phytochemicals and Antioxidant Activities
2007 - Elsevier BV | Food Chemistry
Victoria Villalta‐Gil, Iria Meléndez-Pérez, Tamara Russell, Simon Surguladze, Joaquim Raduà, Montserrat Fusté, Christian Stephan‐Otto, Josep María Haro,
Neurofunctional and behavioral abnormalities in facial emotion processing (FEmoP) have been consistently found in schizophrenia patients, but studies assessing brain functioning in early phases are scarce and the variety of experimental paradigms in current literature make comparisons difficult. The present work focuses on assessing FEmoP in people experiencing a psychotic episode for the first time with different experimental paradigm approaches.Twenty-two patients with a first psychotic episode ( ...
Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
2013 - Elsevier BV | Schizophrenia Research
J. Bosch-Fusté, Elisa Sartini, Cintia Flores, Josep Caixach, Elvira López‐Tamames, Susana Buxaderas,
To evaluate the viability of the A280 value for monitoring the development of cava sparkling wine during its ageing in contact with lees and its commercial shelf life, an accelerated test was applied to four types of sparkling wines obtained at industrial scale. All cava types were stored under oxygen and carbon dioxide conditions at 37 °C for 13 weeks. During the accelerated test, a positive relationship between absorbance at 280 nm (A280) and time was observed, while the main phenolic compounds ...
Tópico(s): Horticultural and Viticultural Research
2008 - Elsevier BV | Food Chemistry
Blanca Goñi-Fuste, Iris Crespo, Cristina Monforte‐Royo, Josep Porta‐Sales, Albert Balaguer, Denise Pergolizzi,
The comprehensive assessment of needs in palliative care identifies where patients most want attention to guide clinical decisions that tailor care provision from their first encounters.To define how and what needs are identified by the comprehensive assessment of needs in the original peer-reviewed articles in the field of palliative care.An integrative systematic review as outlined by Whittemore and Knafl. Quality appraisal performed using the Mixed Methods Appraisal Tool.PubMed, CINAHL, PsycINFO, ...
Tópico(s): Grief, Bereavement, and Mental Health
2021 - SAGE Publishing | Palliative Medicine
Eva Sanchez Armengol, Òscar Domènech, Ester Fusté, Isabel Pérez-Guillén, Jordi Hernández‐Borrell, Josep M. Sierra, Miguel Viñas,
Despite its use was abandoned several decades ago, the polycationic peptide colistin has become the last hope to treat severe infections caused by multidrug-resistant Gram-negative bacteria. Thus, the development of colistin resistance may seriously compromise the efficacy of treatment. Moreover, colistin has high toxicity being dose dependent. A potentially effective strategy to avoid resistance may be to combine colistin with other antimicrobials. This may help in the rescue of old antimicrobials ...
Tópico(s): Bacterial Genetics and Biotechnology
2019 - Dove Medical Press | Infection and Drug Resistance
Paula Espinal, Ester Fusté, Josep M. Sierra, Guadalupe Jiménez-Galisteo, Teresa Vinuesa, Miguel Viñas,
Introduction To overcome the challenge of multidrug resistance, natural and synthetic peptides are candidates to become the basis of innovative therapeutics, featuring diverse mechanisms of action. Traditionally, the time elapsed from medical discoveries to their application is long. The urgency derived from the emergence of antibiotic resistance recommends an acceleration of research to put the new weapons in the hands of clinicians.Areas covered This narrative review introduces ideas and suggestions ...
Tópico(s): Antibiotic Resistance in Bacteria
2023 - Taylor & Francis | Expert Opinion on Biological Therapy
Anna Ruiz‐Comellas, Glòria Saüch Valmaña, Queralt Miró Catalina, Isabel Gómez Baena, Jacobo Mendioroz, Pere Roura‐Poch, Anna Sabata Carrera, Irene Cornet Pujol, Àngels Casaldàliga Solà, Montserrat Fusté Gamisans, Carme Saldaña Vila, Lorena Vázquez Abanades, Josep Vidal‐Alaball,
The percentage of older people is increasing worldwide. Loneliness and anxious–depressive states are emerging health conditions in this population group, and these conditions give rise to higher morbidity and mortality. Physical activity (PA) and social relationships have been linked to physical and mental health. The objective of this study was to evaluate whether a 4-month programme of moderate PA in a group would improve the emotional state, levels of social support, and quality of life in a sample ...
Tópico(s): Health and Wellbeing Research
2022 - Multidisciplinary Digital Publishing Institute | Healthcare
Josep M. Sierra, Ester Fusté, Francesc Rabanal, Teresa Vinuesa, Miguel Viñas,
Introduction: The recent dramatic increase in the incidence of antimicrobial resistance has been recognized by organizations such as the United Nations and World Health Organization as well as the governments of the USA and several European countries. A relatively new weapon in the fight against severe infections caused by multi-drug resistant bacteria is antimicrobial peptides (AMPs). These include colistin, currently regarded as the last line of antimicrobial therapy against multi-drug resistant ...
Tópico(s): Probiotics and Fermented Foods
2017 - Taylor & Francis | Expert Opinion on Biological Therapy
Rebeca Moreira, Pablo Balseiro, Josep V. Planas, Berta Fusté, Sergi Beltrán, Beatriz Novoa, António Figueras,
Background The Manila clam (Ruditapes philippinarum) is a worldwide cultured bivalve species with important commercial value. Diseases affecting this species can result in large economic losses. Because knowledge of the molecular mechanisms of the immune response in bivalves, especially clams, is scarce and fragmentary, we sequenced RNA from immune-stimulated R. philippinarum hemocytes by 454-pyrosequencing to identify genes involved in their immune defense against infectious diseases. Methodology ...
Tópico(s): Calcium Carbonate Crystallization and Inhibition
2012 - Public Library of Science | PLoS ONE
María Luisa de la Puente, Josep Fusté,
En el año 2004 se da un impulso político a la planificación y evaluación sanitaria en Cataluña, con el objetivo de dirigir más eficazmente el presupuesto público a la salud de los ciudadanos y a la calidad del sistema. La planificación sanitaria se ejerce desde las estructuras centrales y regionales del Departamento de Salud y se desarrolla mediante instrumentos de planificación. El Mapa Sanitario, Sociosanitario y de Salud Pública es el nuevo instrumento de planificación de servicios. Elabora estrategias ...
Tópico(s): Health disparities and outcomes
2008 - Elsevier BV | Medicina Clínica
Montserrat Fusté, Raquel Pinacho, Iria Meléndez-Pérez, Núria Villalmanzo, Victoria Villalta‐Gil, Josep María Haro, Belén Ramos,
Alterations of transcription factor specificity protein 4 (SP4) and 1 (SP1) have been linked to different neuropsychiatric diseases. Reduced SP4 and SP1 protein levels in the prefrontal cortex have been associated with bipolar disorder and schizophrenia, respectively, suggesting that both factors could be involved in the pathogenesis of disorders with psychotic features. The aim of this study was to investigate whether the reduction of SP1, SP4 and SP3 protein and mRNA expression in peripheral blood ...
Tópico(s): Genetic Associations and Epidemiology
2013 - Elsevier BV | Journal of Psychiatric Research
Montserrat Fusté, Astrid Pauls, Amanda Worker, Antje A. T. S. Reinders, Andrew Simmons, Steven Williams, Josep María Haro, Kate Hazelgrove, Susan Pawlby, Susan Conroy, Costanza Vecchio, Gertrude Seneviratne, Carmine M. Pariante, Mitul A. Mehta, Paola Dazzan,
Abstract Postpartum psychosis (PP) is the most severe psychiatric disorder associated with childbirth. The risk of PP is very high in women with a history of bipolar affective disorder or schizoaffective disorder. However, the neurobiological basis of PP remains poorly understood and no study has evaluated brain structure in women at risk of, or with, PP. We performed a cross-sectional study of 256 women at risk of PP and 21 healthy controls (HC) in the same postpartum period. Among women at risk, ...
Tópico(s): Schizophrenia research and treatment
2017 - Springer Nature | Translational Psychiatry
María Calderon-Mediavilla, Regina Vila-Badía, Montse Dolz, Anna Butjosa, Ana Barajas, N. Del Cacho, Bernardo Sánchez, Marta Pardo, Iris Baños, Judith Usall, Susana Ochoa, Susana Araya, Belén Arranz, María Verónica Muñoz Arteaga, R Pérez Asensio, J. Autonell, Iris Baños, M. Bañuelos, Ana Barajas, Marta Barceló, Michel Blanc, Miquel Borràs, Ester Busquets, Janina Carlson, Vanessa Carral, Elena Castro, Casimiro Corbacho, Marta Coromina, I. Dachs, Laia Miquel, Montse Dolz, Margarita Domènech, María Elías, I. Espezel, E. Falo, Arnau Fargas, Alexandrina Foix, Montserrat Fusté, M. Godrid, David Delgado‐Gómez, Olga Molinero González, Luis Granell, L. Gumà, Josep María Haro, Sávia Denise Silva Carlotto Herrera, Elena Huerta, Fernando Lacasa, Nuria de Mas, L. Martí, R. Gómez Martínez, Josep Lluís Matalí, A. Miñambres, Daniel Muñoz, Verónica Pérez Muñoz, R. Nogueroles, M. Núñez, Susana Ochoa, José Ortíz, Marta Pardo, M. Planella, Trinidad Pélaez, S. Peruzzi, J. Portos, S. Benítez Rivero, María José Cubillas Rodríguez, E. Rubio, Stéphanie Sammut, Margot Sanchez, Bernardo Sánchez, Eduardo Serrano‐Troncoso, C. Solís, Christian Stephan‐Otto, Patricia García Tabuenca, S. Teba, A. Torres, David Urbano, Judith Usall, Míriam Vilaplana, V. Villalta, A. Ahicart, M. Álvarez, Belén Arranz, V. Barneda, J.L. Bogas, Rosalba Rosales Bonilla, Anna Butjosa, T. Casalí, B. Fernández Colomer, Marta Coromina, A. Cuautle, Jorge Cuevas‐Esteban, Ruth Cunill, O. Cuñat, N. Del Cacho, B. del Hoyo, Y. Delisau, Montse Dolz, I. Ferrer, Alexandrina Foix, N. Grases, Maria Iglesias‐González, G. Ledesma-Ipaguirre, Cristina López-Ortiz, P. Membrive, A. Miñambres, Daniel Muñoz‐Samons, Susana Ochoa, N. Pastrana, María José Cubillas Rodríguez, Trinidad Pélaez, C. Saltó, S. Sibelo, Christian Núñez, M. Núñez, Marta Pardo, J. Redin, IRiera-Lopez de Aguileta, C. Romans, Elena Rubio‐Abadal, Adriana Maria Barsante Santos, L. Sole, Aleix Arnau‐Soler, S. Teba, Judith Usall, Regina Vila-Badía,
Tópico(s): Tryptophan and brain disorders
2020 - Springer Science+Business Media | European Child & Adolescent Psychiatry
Anna Butjosa, Juana Gómez‐Benito, Inez Myin‐Germeys, Ana Barajas, Iris Baños, Judith Usall, Norma Grau, Luis Granell, Andrea Sola, Janina Carlson, Montserrat Dolz, Bernardo Sánchez, Josep María Haro, Susana Ochoa, Susana Araya, Belén Arranz, María Verónica Muñoz Arteaga, R Pérez Asensio, J. Autonell, Iris Baños, M. Bañuelos, Ana Barajas, Marta Barceló, Michel Blanc, Miquel Borràs, Ester Busquets, Anna Butjosa, Janina Carlson, Vanessa Carral, Elena Castro, Casimiro Corbacho, Marta Coromina, I. Dachs, Montserrat Dolz, Margarita Domènech, María Elías, I. Espezel, E. Falo, Arnau Fargas, Alexandrina Foix, Montserrat Fusté, M. Godrid, David Delgado‐Gómez, Olga Molinero González, Luis Granell, L. Gumà, Josep María Haro, Sávia Denise Silva Carlotto Herrera, Elena Huerta, Fernando Lacasa, Nuria de Mas, L. Martí, R. Gómez Martínez, Josep Lluís Matalí, A. Miñambres, Laia Miquel, Daniel Muñoz, Verónica Pérez Muñoz, R. Nogueroles, Susana Ochoa, José Ortíz, Marta Pardo, M. Planella, Trinidad Pélaez, S. Peruzzi, S. Benítez Rivero, María José Cubillas Rodríguez, E. Rubio, Stephen Sammut, Margot Sanchez, Bernardo Sánchez, Eduardo Serrano‐Troncoso, C. Solís, Christian Stephan‐Otto, Patricia García Tabuenca, S. Teba, A. Torres, David Urbano, Judith Usall, Míriam Vilaplana, V. Villalta,
Stressful life events (SLEs) are important indicators prior to the onset of first-episode psychosis (FEP). Although there are well-validated interviews and self-reports for assessing SLE on proximate events, unfortunately there are no instruments to assess SLE covering an entire lifetime. This study includes detailed specific items of childhood, adolescence, and adulthood focused on the presence of SLE, emotional impact (stressfulness), and the age at which the event occurred. Our research describes ...
Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
2017 - Elsevier BV | Journal of Psychiatric Research
Pilar Brugulat, Elisa Séculi, Josep Fusté, Salvi Juncà, V. Martínez, Antònia Medina, Mercè Mercader, Emília Sànchez,
Conocer la opinión de los profesionales sanitarios sobre el Plan de Salud (PS) de Cataluña y obtener nuevos elementos para la formulación y gestión de nuevos planes. Combinación de metodología cuantitativa y cualitativa. Encuesta postal a personal médico y de enfermería, por muestreo aleatorio polietápico con estratificación. Se obtuvieron 3.223 cuestionarios (tasa de respuesta del 34,1%). Entrevista a una muestra de conveniencia formada por 41 profesionales asistenciales y de la gestión. El PS es ...
Tópico(s): Health Policy Implementation Science
2003 - Elsevier BV | Gaceta Sanitaria