César Augusto Henao, Juan Carlos Muñoz, Juan‐Carlos Ferrer,
Using personnel scheduling to reduce overstaffing and understaffing in a service industry across multiple periods is often undermined by lack of flexibility due to the exclusive use of specialized personnel. This study analyses the impacts of assigning multi-skilled personnel to different activities and its potential for improving schedule efficiency. A proposed mixed integer linear programming model determines which employees are trained to work in which activities and their assignments over a ...
Tópico(s): Vehicle Routing Optimization Methods
2015 - Palgrave Macmillan | Journal of the Operational Research Society
César Augusto Henao, Juan‐Carlos Ferrer, Juan Carlos Muñoz, Jorge Vera,
Variability and seasonality is an inherent characteristic in many service industries. This leads to the problem of mismatch between employee supply and demand. In this work we present a mixed integer linear programming model and a constructive heuristic to address this problem. The proposed methodology applies the concept of multiskilling, an attractive source of flexibility for improving service levels and reducing the costs to firms of staff shortages and surpluses induced by employee demand variability. ...
Tópico(s): Scheduling and Optimization Algorithms
2016 - Elsevier BV | International Journal of Production Economics
César Augusto Henao, Juan Carlos Muñoz, Juan‐Carlos Ferrer,
A new methodology is presented for structuring the multiskilling characteristics of a set of initially single-skilled employees in the context of a multi-department service sector business, more specifically in the retail industry. Assuming stochastic demand under continuous modeling of the workforce, the methodology decomposes the multiskilling problem into three stages that are then solved sequentially. The first stage delivers a novel analytic expression for estimating the number of multiskilled ...
Tópico(s): Transportation Planning and Optimization
2018 - Elsevier BV | Computers & Industrial Engineering
Jorge Corona‐Castuera, Daniela Rodriguez-Delgado, John Henao, Juan Carlos Castro-Sandoval, Carlos A. Poblano-Salas,
As a larger elderly human population is expected worldwide in the next 30 years, the occurrence of aging-associated illnesses will also be increased. The use of prosthetic devices by this population is currently important and will be even more dramatic in the near future. Hence, the design of prosthetic devices able to reduce some of the problems associated with the use of current components, such as stress shielding, reduced mobility, infection, discomfort, etc., becomes relevant. The use of additive ...
Tópico(s): Bone Tissue Engineering Materials
2021 - American Chemical Society | ACS Omega
Elizabeth Emperatriz García-Salirrosas, Ángel Acevedo-Duque, Viviana Marin Chaves, Paula Andrea Mejía Mejía Henao, Juan Carlos Molano,
The aim of the research is to gain an understanding of consumer behavior in developing countries in the electronic environment. For this purpose, the four constructs of the PREVEINCOSA scale were analyzed: purchase intention as the dependent variable and trust, perceived value, and satisfaction as the determining variables of the former. For this purpose, by means of convenience sampling, an online questionnaire was shared with citizens in Mexico, Peru, and Colombia. A total of 330 questionnaires ...
Tópico(s): Digital Marketing and Social Media
2022 - Multidisciplinary Digital Publishing Institute | Sustainability
El dano es uno de los temas de mayor importancia en el derecho. En esta obra el autor estudia los elementos necesarios para que se pueda predicar que el dano existe, esto es, que sea cierto y personal; examina la tipologia del dano, o sea la forma como se presentan los diversos rubros del mismo y, por ultimo, estudia la liquidacion del dano a partir de ejemplos concretos. Incluye ademas un gran acopio de informacion jurisprudencial y doctrinaria que cubre la evolucion de la responsabilidad del poder ...
Tópico(s): Administrative Law and Governance
2007 - | Books
Andrés Fernando Ospina Garzón,
... la jurisprudencia. Se incluye un estudio preliminar de Juan Carlos Henao acerca del aporte de la jurisprudencia administrativa al ...
Tópico(s): Legal processes and jurisprudence
2013 - | Books
<p>Este trabajo comporta un análisis crítico de la reparación del daño en el derecho administrativo colombiano. A partir del estudio de las nociones de ‘daño’ y ‘reparación’, esenciales para la atribución de responsabilidad civil, se demuestra el carácter limitado del entendimiento clásico de la responsabilidad extracontractual del Estado. Así pues, el artículo propone una comprensión de la reparación a partir del criterio de ‘universalización’, con independencia de las acciones por medio de ...
Tópico(s): Criminal Justice and Penology
2015 - Universidad Externado de Colombia | Revista de Derecho Privado
Juan Carlos Henao, Adriana Grismaldo, Alfonso Barreto, Viviana Marcela Rodríguez-Pardo, Claudia Camila Mejía-Cruz, Efrain Leal-García, Rafael Pérez-Núñez, Patricio Rojas, Ramón Latorre, Ingrid Carvacho, Yolima P. Torres,
Various families of ion channels have been characterized in mesenchymal stem cells (MSCs), including some members of transient receptor potential (TRP) channels family. TRP channels are involved in critical cellular processes as differentiation and cell proliferation. Here, we analyzed the expression of TRPM8 channel in human bone marrow MSCs (hBM-MSCs), and its relation with osteogenic differentiation. Patch-clamp recordings showed that hBM-MSCs expressed outwardly rectifying currents which were increased ...
Tópico(s): Ion channel regulation and function
2021 - Frontiers Media | Frontiers in Cell and Developmental Biology
Laura Rey-Vargas, Juan Carlos Mejía-Henao, María Carolina Sanabria‐Salas, Silvia J. Serrano‐Gómez,
Abstract Background Breast cancer clinical management requires the assessment of hormone receptors (estrogen (ER) and progesterone receptor (PR)), human epidermal growth factor receptor 2 (HER2) and cellular proliferation index Ki67, by immunohistochemistry (IHC), in order to choose and guide therapy according to tumor biology. Many studies have reported contradictory results regarding changes in the biomarker profile after neoadjuvant therapy (NAT). Given its clinical implications for the disease management, ...
Tópico(s): Cancer Cells and Metastasis
2020 - BioMed Central | BMC Cancer
Carlos A. Arias, Julieta Henao, José Hernán Martínez, Juan Carlos Arias, Leonardo Beltrán,
Omeprazole is metabolized by the hepatic cytochrome P450 (CYP) 2C19 enzyme to 5-hydroxyomeprazole. CYP2C19 exhibits genetic polymorphisms responsible for the presence of poor metabolizers (PMs), intermediate metabolizers (IMs) and extensive metabolizers (EMs). The defective mutations of the enzyme and their frequencies change between different ethnic groups; however, the polymorphism of the CYP2C19 gene has not been studied in Colombian mestizos. The aim of this study was to evaluate the genotype and ...
Tópico(s): Drug Transport and Resistance Mechanisms
2007 - BioMed Central | BMC Clinical Pharmacology
María Paula Acosta-Luque, Julián E. López, Nancy Henao, Daniela Zapata, Juan Carlos Pacheco Giraldo, Juan F. Saldarriaga,
Abstract Soil contamination by Pb can result from different anthropogenic sources such as lead-based paints, gasoline, pesticides, coal burning, mining, among others. This work aimed to evaluate the potential of P-loaded biochar (Biochar-based slow-release P fertilizer) to remediate a Pb-contaminated soil. In addition, we aim to propose a biomonitoring alternative after soil remediation. First, rice husk-derived biochar was obtained at different temperatures (450, 500, 550, and 600 °C) (raw biochars). ...
Tópico(s): Arsenic contamination and mitigation
2023 - Nature Portfolio | Scientific Reports
Camilo Hurtado‐Parrado, Myriam Carmenza Sierra-Puentes, Mohammed El Hazzouri, Alexandra Morales, Diana Gutiérrez-Villamarín, Laura Maria Velásquez‐Díaz, Andrea Correa‐Chica, Juan Carlos Rincón-Vásquez, Karen Henao, Juan Gabriel Castañeda Polanco, Wilson López‐López,
Control of negative emotions (e.g., anger and fear) by political cues perpetuate intractable conflict by mobilizing public support for aggressive actions. Halperin et al. (2013) found that reappraisal – an adaptive form of emotion regulation – decreased negative emotions triggered by anger-inducing information related to the Israeli-Palestinian conflict, and increased support for conciliatory statements. We tested these effects in the context of the conflict between the Colombian government and the Fuerzas ...
Tópico(s): Resilience and Mental Health
2019 - Frontiers Media | Frontiers in Psychology
Jaime Eduardo Becerra, Óscar Zorro, Rafael Ruiz‐Gaviria, Camilo Castañeda‐Cardona, Margarita Otálora Esteban, Sara Henao-Romero, S. Navarrete, Juan Carlos Acevedo González, Diego Rosselli,
Parkinson disease (PD) is a chronic multifaceted neurodegenerative disorder of adult onset that affects quality of life and places a burden on patients, caregivers, and society. In early disease, dopaminergic therapy improves motor symptoms, but as the disease progresses, symptoms tend to increase in frequency and severity, even with best medical treatment (BMT). Deep brain stimulation (DBS) becomes an option for certain patients, but cost becomes an important issue. We performed a systematic review ...
Tópico(s): Autism Spectrum Disorder Research
2016 - Elsevier BV | World Neurosurgery
Euclides Murcia Londoño, Juan Carlos Henao López,
This review article presents some epistemological concretely training elements of mathematical thinking to the level of primary and secondary education in Colombia, within the possible methodological errors made in the transformation processes in common language towards the structured mathematical language; It also presents some new training trends as a starting point for a research that is currently being developed.
Tópico(s): Business, Education, Mathematics Research
2015 - | Entre ciencia e ingeniería
Jairo A. Grajales, Héctor Fabio Quintero Riaza, Carlos Romero, Edison Henao, Juan Fernando López López, Daniela Torres,
An estimation method of the combustion chamber pressure, in an internal combustion engine, based on the processing of the vibration (acceleration) signal of the cylinder head, at constant speed and no load conditions is presented in this paper. The model is created based on the comparison of the vibration and pressure signals around the peaks of highest vibration, after a preprocessing and filtering of the signal using the most similar frequency bands between the sources. A polynomial regression ...
Tópico(s): Combustion and flame dynamics
2016 - JVE International | Journal of Vibroengineering
Zulma M. Cucunubá, Pierre Nouvellet, Lesong Conteh, Mauricio Vera, Vı́ctor Manuel Angulo, Juan Carlos Dib, Gabriel Parra-Henao, Marı́a-Gloria Basáñez,
WHO's 2020 milestones for Chagas disease include having all endemic Latin American countries certified with no intradomiciliary Trypanosoma cruzi transmission, and infected patients under care. Evaluating the variation in historical exposure to infection is crucial for assessing progress and for understanding the priorities to achieve these milestones.Focusing on Colombia, all the available age-structured serological surveys (undertaken between 1995 and 2014) were searched and compiled. A total of ...
Tópico(s): Parasites and Host Interactions
2017 - BMJ | BMJ Global Health
Michael Mac-Vicar, Juan‐Carlos Ferrer, Juan Carlos Muñoz, César Augusto Henao,
Retailers must frequently deal with alterations in planned customer service levels due to unexpected demand variations or unscheduled employee absences. Although personnel scheduling techniques have been extensively studied and successfully applied, previous treatments of scheduling adjustments in response to demand and employee contingencies have not systematically considered all of the relevant issues. After presenting a mathematical specification of the problem, this study develops various algorithms ...
Tópico(s): Vehicle Routing Optimization Methods
2017 - Elsevier BV | Computers & Industrial Engineering
Esteban Álvarez, Juan‐Carlos Ferrer, Juan Carlos Muñoz, César Augusto Henao,
A work shift scheduling methodology is presented that can assign shifts incorporating multiple breaks, providing the flexibility vital to service sector firms for reducing staff surpluses and shortages and thereby improve staff demand coverage. The proposed approach differs from previous works in the literature because it attempts to minimize the levels of overstaffing and understaffing, but also the possible negative impacts associated to a strategy of multiple breaks. The approach is built around ...
Tópico(s): Optimization and Mathematical Programming
2020 - Elsevier BV | Computers & Industrial Engineering
Jorge Alejandro Henao, Nora Vanegas, Oscar David Cano, Juan Carlos Hiromi, Marı́a Teresa Rugeles,
Currently, at least 42 million people are infected worldwide with the human immunodeficiency virus type 1 (HIV-1). Of these, 3.2 million are children infected, in 90% of the cases, through vertical transmission. In Colombia, approximately 200,000 persons have been infected since the beginning of the pandemic, with an increasing trend in the seroprevalence among pregnant women. Although HIV-1 is basically lymphotropic, its capacity to invade the central nervous system (CNS) is well known, generating ...
Tópico(s): Tryptophan and brain disorders
2005 - National Institute of Health | Biomédica
Stephen R. Benoit, Beatriz López, Wences Arvelo, Olga L. Henao, Michele B. Parsons, Lissette Reyes, Juan Carlos Moir, Kim A. Lindblade,
Campylobacteriosis is one of the leading causes of gastroenteritis worldwide. This study describes the epidemiology of laboratory-confirmed Campylobacter diarrheal infections in two facility-based surveillance sites in Guatemala.Clinical, epidemiologic, and laboratory data were collected on patients presenting with acute diarrhea from select healthcare facilities in the departments of Santa Rosa and Quetzaltenango, Guatemala, from January 2008 through August 2012. Stool specimens were cultured for ...
Tópico(s): Food Safety and Hygiene
2013 - Elsevier BV | Journal of Epidemiology and Global Health
Tópico(s): Comparative constitutional jurisprudence studies
1999 - National Autonomous University of Mexico | Revista de la Facultad de Derecho de México
Juan Carlos Henao Zambrano, Olga Teresa Barreto Cruz,
Dado el constante crecimiento demográfico a nivel mundial observado en el paso del tiempo, se ha percibido la necesidad de tener un esquema social donde la oferta de alimentos saludables sea constante y suficiente para solventar las insuficiencias existentes en la población humana. Ante esta situación, la eficiencia de los modelos pecuarios de producción animal se ha visto comprometida como consecuencia de la competencia de las especies animales por los recursos alimenticios que el hombre consume. ...
Tópico(s): Coconut Research and Applications
2016 - Universidad Nacional Abierta y a Distancia | Revista de Investigación Agraria y Ambiental
Santiago Echeverry, Adriana Grismaldo, C. A. Sanchez, Cristian Sierra, Juan Carlos Henao, Sara T. Granados, Jhon Jairo Sutachan, Yolima P. Torres,
Due to their capacity to proliferate, migrate, and differentiate, mesenchymal stem cells (MSCs) are considered to be good candidates for regenerative medicine applications. The mechanisms underlying proliferation and differentiation of MSCs have been study. However, much less is known about the mechanisms regulating the migration of MSCs. Platelet lysate (PL), a supplement used to promote cell expansion, has been shown to promote MSCs migration; however the underlying mechanism are unknown. Here, ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2020 - Frontiers Media | Frontiers in Physiology
Mariano Altamiranda‐Saavedra, Luis Osorio‐Olvera, Carlos Yáñez‐Arenas, Juan Carlos Marín-Ortiz, Gabriel Parra-Henao,
Ecoepidemiological scenarios for Chagas disease transmission are complex, so vector control measures to decrease human–vector contact and prevent infection transmission are difficult to implement in all geographic contexts. This study assessed the geographic abundance patterns of two vector species of Chagas disease: Triatoma maculata (Erichson, 1848) and Rhodnius pallescens (Barber, 1932) in Latin America. We modeled their potential distribution using the maximum entropy algorithm implemented in ...
Tópico(s): Evolution and Genetic Dynamics
2020 - Public Library of Science | PLoS ONE
Wences Arvelo, Aron J. Hall, Olga L. Henao, Beatriz López, Chris Bernart, Juan Carlos Moir, Lissette Reyes, Susan P. Montgomery, Oliver Morgan, Alejandra Estévez, Michele B. Parsons, María R. López, Gerry Gomez, Jan Vinjé, Nicole Gregoricus, Umesh D. Parashar, Eric D. Mintz, John P. McCracken, Joe P. Bryan, Kim A. Lindblade,
Abstract Background Diarrhea is a major cause of morbidity and mortality, yet incidence and etiology data are limited. We conducted laboratory-based diarrhea surveillance in Guatemala. Methods A diarrhea case was defined as ≥3 loose stools in a 24-h period in a person presenting to the surveillance facilities. Epidemiologic data and stool specimens were collected. Specimens were tested for bacterial, parasitic, and viral pathogens. Yearly incidence was adjusted for healthcare seeking behaviors determined ...
Tópico(s): Food Security and Health in Diverse Populations
2019 - BioMed Central | BMC Public Health
Lily Johanna Toro, Germán Alberto Téllez Ramírez, Diana Carolina Henao, Juan David Rivera Duran, Juan Pablo Bedoya Agudelo, Jhon Carlos Castaño Osório,
Dung beetles are exposed to a complex microbiological ecosystem during their life cycle. Characterization of novel host-defense peptides (HDP) is essential to understanding the host innate immune response in insects. It constitutes a promising alternative to look for new therapeutic agents against pathogenic microbes. We identified four new HDP, Oxysterlins 1, 2, 3, and 4 from the transcriptome of the Oxysternon conspicillatum dung beetle. These HDP display a highly conserved signal peptide and a ...
Tópico(s): Insect Resistance and Genetics
2017 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Valentina Arias, Wilson Daniel Caicedo Chacon, Angélica M. Carvajal Soto, Germán Ayala Valencia, Juan Carlos Granada Echeverri, Ana Cecilia Agudelo Henao,
Abstract Carbon quantum dots (CQDs) are a special type of nanostructure characterized for their low toxicity, environmentally friendliness, and ease of manufacture from varied carbon sources like carbohydrates. This carbon source is abundant in natural products and organic wastes, and it is suitable to be used in food applications like nano sensors for food quality and safety. Indeed, CQDs are foreseen as a potential new type of practical and unexpensive sensor to detect harmful substances commonly ...
Tópico(s): Nanocluster Synthesis and Applications
2021 - Wiley | Starch - Stärke
... la democracia.Propuestas para una refundación.Prólogo de Juan Carlos Henao (Bogotá, Universidad Externado de Colombia) 202 pp.En ...
Tópico(s): Public Policy and Governance
2021 - Pontificia Universidad Catolica de Chile | Revista Chilena de Derecho
T. Sosa, Natividad Chaves, Juan Carlos Alías, José Carlos Escudero, Fernando Henao, Carlos Gutiérrez‐Merino,
Tópico(s): Chemical synthesis and alkaloids
2004 - Springer Science+Business Media | Journal of Chemical Ecology