Manuel Romero‐Gómez, Juan Córdoba, Rodrigo Jover, Juan A. del Olmo, M Cabello Ramirez, Ramón Rey, Enrique de‐Madaria, Carmina Montoliú, David Brandariz-Núñez, Montse Flavià, Luís Compañy, José Rodrigo, Vicente Felipo,
Minimal hepatic encephalopathy (MHE) is mainly diagnosed using psychometric tests such as the psychometric hepatic encephalopathy score (PHES). Despite the clinical and social relevance of MHE, psychometric testing is not widespread in routine clinical care. We assessed the usefulness of the critical flicker frequency (CFF), for the diagnosis of MHE and for the prediction of the development of overt episodes of HE. The normal range of PHES in the Spanish population was evaluated in a control group. ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2007 - Lippincott Williams & Wilkins | Hepatology
Manuel Romero‐Gómez, Juan Córdoba, Rodrigo Jover, Juan del Olmo, Ana Fernández‐Palacín, Montse Flavià, Luís Compañy, María Poveda, Vicente Felipo,
La encefalopatía hepática mínima (EHM) ha ganado importancia en la práctica clínica porque su presencia se asocia a un claro deterioro de la calidad de vida del paciente cirrótico y a la incapacidad de conducir automóviles, y es la antesala para el desarrollo de episodios de encefalopatía hepática clínica. La Psychometric Hepatic Encephalopathy Score (PHES), compuesta por el test de conexión numérica A (TCN-A), el test de conexión numérica B (TCN-B), el test de símbolos y números (TSN), el test de marcación ...
Tópico(s): Alcohol Consumption and Health Effects
2006 - Elsevier BV | Medicina Clínica
Juan Parrado, E. Miramontes, María Jover, Juan Fco Gutierrez, Laura Collantes de Terán, Juan Bautista,
The production, stabilization, by enzymatic treatment, physicochemical composition, and biological properties (including the anti-proliferative activity), of a water-soluble rice bran enzymatic extract (RBEE) are described. The main component of RBEE is proteins (38.1%) – in the form of peptide and free amino acids – having a 6% content of sulfur amino acids. The second component is fat (30.0%), with oleic and linoleic acids as the major components, and 1.2 mg/g of γ-oryzanol. Carbohydrates (14.2%) are comprised ...
Tópico(s): Phytase and its Applications
2005 - Elsevier BV | Food Chemistry
Raquel Rollín, P. Tornero, Fernando Marco, Emilio Camafeita, Enrique Calvo, L. López-Durán, Juan Ángel Jover, Juan Antonio López, José Ramón Lamas, Benjamín Fernández‐Gutiérrez,
Cartilage damage is a major problem in osteoarthritis (OA).To gain insight into the pathogenesis of OA, we have analyzed the differential proteome of articular chondrocytes from these patients.Protein extracts were prepared from cultured chondrocytes from 6 patients with end-stage OA and 6 normal donors and were analyzed by 2D-DIGE.Differentially expressed proteins were identified by mass spectrometry (MS).Significant differential expression was observed for 27 proteins, with 14 underexpressed and ...
Tópico(s): Immune Response and Inflammation
2008 - OMICS Publishing Group | Journal of Proteomics & Bioinformatics
David S. Peñaranda, L. Pérez, Víctor Gallego, M. Jover, Juan F. Asturiano,
Sperm production has been obtained from European and Japanese eels, but its quality and quantity tend to be changeable. So, its cryopreservation has been tried in both species. Dimethyl sulfoxide (Me2SO) is the best cryoprotectant for European eel sperm, but increases the medium osmolality, inducing the activation of spermatozoa motility. To avoid this, different combinations of pH (6.5 and 8.5) and NaHCO3 concentrations (20, 40 and 80 mM) were tested with two Me2SO concentrations (5% and 10%). Foetal ...
Tópico(s): Reproductive Biology and Fertility
2009 - Elsevier BV | Cryobiology
Raquel Rollín, Fernando Marco, Emilio Camafeita, Enrique Calvo, L. López-Durán, J. A. Jover, Juan Antonio López, Benjamín Fernández‐Gutiérrez,
Adult mesenchymal stem cells (MSCs) are multipotent cells whose primary reservoir is bone marrow (BM). Following situations of extensive tissue damage, MSCs are mobilized and migrate to the site of injury. Osteoarthritis (OA) is a condition that involves extensive cartilage and bone damage. To gain insight into the pathogenesis of OA, we have analyzed the differential BM-MSCs proteome of OA patients.MSCs protein extracts were prepared from BM aspirates from six patients with OA and from six hip fracture ...
Tópico(s): Mesenchymal stem cell research
2008 - Elsevier BV | Osteoarthritis and Cartilage
David S. Peñaranda, L. Pérez, Víctor Gallego, Rodolfo Barrera, M. Jover, Juan F. Asturiano,
Contents The sperm of European eel shows a high density and the time of spermatozoa motility is very short after activation with sea water. These characteristics make difficult the sperm handling and its quality assessment. Several diluents were previously described for the Japanese eel obtaining over 3 weeks’ conservation times under refrigeration, but they rendered bad results in the European species. In the present study, several diluents were developed taking as basis the P1 medium, and using ...
Tópico(s): Reproductive Biology and Fertility
2008 - Wiley | Reproduction in Domestic Animals
Maïté Courel, Alex Soler-Jover, Juan L. Rodriguez‐Flores, Sushil K. Mahata, Salah Élias, Maïté Montero‐Hadjadje, Youssef Anouar, Richard J. Giuly, Daniel T. O’Connor, Laurent Taupenot,
Processes underlying the formation of dense core secretory granules (DCGs) of neuroendocrine cells are poorly understood. Here, we present evidence that DCG biogenesis is dependent on the secretory protein secretogranin (Sg) II, a member of the granin family of pro-hormone cargo of DCGs in neuroendocrine cells. Depletion of SgII expression in PC12 cells leads to a decrease in both the number and size of DCGs and impairs DCG trafficking of other regulated hormones. Expression of SgII fusion proteins ...
Tópico(s): RNA Interference and Gene Delivery
2010 - Elsevier BV | Journal of Biological Chemistry
David S. Peñaranda, Francisco Marco‐Jiménez, L. Pérez, Víctor Gallego, I. Mazzeo, J.S. Vicente, M. Jover, Juan F. Asturiano,
In order to study different storage conditions, dilution ratios and additives for fresh European eel sperm were assayed to determinate the optimum conditions for short-term storage. Two experiments were conducted, analysing the sperm motility and its viability at different times of incubation (1, 4, 7, 11 and 14 days). In the first part of the work, 19 pooled samples were used, and seven in the second experiment. Firstly, exposure to atmospheric and air-limited conditions were compared, registering ...
Tópico(s): Reproductive Biology and Fertility
2010 - Wiley | Journal of Applied Ichthyology
DL Garzón, David S. Peñaranda, L. Pérez, Francisco Marco‐Jiménez, X Espert, Tamás Müller, M. Jover, Juan F. Asturiano,
Contents The main objective of the present study was to evaluate the influence of pH and bicarbonate concentration in the activation or inhibition of European eel ( Anguilla anguilla ) spermatozoa and to evaluate the effect of different cryoprotectants: dimethyl sulphoxide (DMSO), acetamide, ethylene glycol, propanol, glycerol and methanol (MeOH). The effect of these factors was evaluated comparing the percentage of motile cells, the percentage of alive cells (by Hoechst staining) and the spermatozoa morphometry ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2007 - Wiley | Reproduction in Domestic Animals
Diana Hernández-Jover, Juan Carlos Pernas, Silvia Gonzalez-Ceballos, Ion Lupu, Josep M. Monill, C. Pérez,
Tópico(s): Pancreatic and Hepatic Oncology Research
2011 - Springer Science+Business Media | Journal of Gastrointestinal Surgery
Francisco Marco‐Jiménez, D.L. Garzón, David S. Peñaranda, L. Pérez, M.P. Viudes-de-Castro, J.S. Vicente, M. Jover, Juan F. Asturiano,
The main aim of the present study was to investigate the effect of sperm freezing medium dilution ratio (1:1, 1:2, and 1:5 v/v), two cryoprotectants: dimethyl sulphoxide (Me2SO) and methanol (MeOH), and the addition of foetal bovine serum (FBS) on the cryopreservation of European eel sperm. The effect of these factors was evaluated comparing post-thawing viability with fluorescent staining (Hoechst bisbenzimide 33258) and the spermatozoa head morphometry, determined with computer-assisted morphology ...
Tópico(s): Reproductive Biology and Fertility
2006 - Elsevier BV | Cryobiology
Carles Gil, Alex Soler-Jover, Juan Blasi, José Aguilera,
The biochemical characterization of the SNARE proteins present in lipid microdomains, also known as "lipid rafts," has been addressed in earlier studies, with conflicting data from different laboratories. In this study, we use rat brain synaptosomes as a model with which to examine the presence of proteins involved in exocytosis in detergent-resistant membranes (DRM), also known as 'lipid rafts.' By means of buoyancy analysis in sucrose gradients of Triton X-100-solubilized synaptosomes, we identified ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2005 - Elsevier BV | Biochemical and Biophysical Research Communications
Francisco Marco‐Jiménez, L. Pérez, M.P. Viudes-de-Castro, D.L. Garzón, David S. Peñaranda, J.S. Vicente, M. Jover, Juan F. Asturiano,
The aim of the present study was to characterise European eel spermatozoa morphometrically, as a basis for future studies on the morphological effects of methods for sperm cryopreservation and sperm quality. This characterisation was carried out measuring several spermatozoa morphology parameters (head length, width, area and perimeter) by scanning electron microscopy (SEM), in comparison with measurements developed in European eel spermatozoa with computer-assisted morphology analysis (ASMA). Spermatozoa ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2005 - Elsevier BV | Theriogenology
Alex Soler-Jover, Juan Blasi, Inma Gómez de Aranda, Piedad Navarro, Maryse Gibert, Michel R. Popoff, Mireia Martín‐Satué,
Epsilon toxin (∊-toxin), produced by Clostridium perfringens types B and D, causes fatal enterotoxemia, also known as pulpy kidney disease, in livestock. Recombinant ∊-toxin–green fluorescence protein (∊-toxin–GFP) and ∊-prototoxin–GFP were successfully expressed in Escherichia coli. MTT assays on MDCK cells confirmed that recombinant ∊-toxin–GFP retained the cytotoxicity of the native toxin. Direct fluorescence analysis of MDCK cells revealed a homogeneous peripheral pattern that was temperature sensitive ...
Tópico(s): Gut microbiota and health
2004 - SAGE Publishing | Journal of Histochemistry & Cytochemistry
Rodrigo Jover, Juan Perez-Serra, Felix Vera, Justin E. Alamo, Carlos Muñoz, Carlos Yago, Ramon Martinez-Ramirez, Jose Vicente Vidal,
Tópico(s): Protein purification and stability
2001 - Lippincott Williams & Wilkins | The American Journal of Gastroenterology
M. Basora, M.J. Colomina, V. Moral, Marcin Lis, E. Boix, José Luis de Miguel Jover, Juan V. Llau, P. Rodrigo, Javier Ripollés, J.M. Calvo Vecino,
The present Clinical practice guide responds to the clinical questions about security in the choice of fluid (crystalloid, colloid or hydroxyethyl starch 130) in patients who require volume replacement during perioperative period of non-cardiac surgeries. From the evidence summary, recommendations were made following the GRADE methodology. In this population fluid therapy based on crystalloids is suggested (weak recommendation, low quality evidence). In the events where volume replacement is not reached ...
Tópico(s): Renal function and acid-base balance
2015 - Elsevier BV | Revista Española de Anestesiología y Reanimación
Nere Zorrozua, Asier Aldalur, Alfredo Herrero, Beñat Diaz, Sergio Delgado, Carola Sanpera, Lluís Jover, Juan Arizaga,
The ecology of opportunistic foragers can be highly dependent on anthropogenic food sources, such as landfills, resulting in changes in several ecological and demographic aspects. The total closure of several landfill sites and the use of deterrence systems to prevent access to the remaining open landfill sites in a region in the northern Iberian Peninsula provided an excellent opportunity to evaluate the consequences of landfills on the trophic ecology of an opportunistic forager, the Yellow‐legged ...
Tópico(s): Fish Ecology and Management Studies
2018 - Wiley | Ibis
Irene Esteban-Millat, Francisco J. Martínez–López, María Pujol-Jover, Juan Carlos Gázquez–Abad, Alejandro Alegret,
This study advances the understanding of the process by which students accept and use e-learning environments. This is a key aspect in studying the online behaviour of students, as it directly influences their conduct in their capacity as users of learning products. To address the lack of empirical data on the adoption of this type of learning environment, we present and validate a model of the phenomenon. The study considers the utilitarian aspects included in the technology acceptance model (TAM) ...
Tópico(s): Digital Marketing and Social Media
2018 - Taylor & Francis | Interactive Learning Environments
Pedro María Martínez Pérez-Crespo, Joaquín Felipe Lanz-García, José María Bravo-Ferrer, María Luisa Cantón‐Bulnes, Adrián Sousa, Josune Goikoetxea Aguirre, José María Reguera-Iglesias, Eva María León Jiménez, Carlos Armiñanzas Castillo, María Ángeles Mantecón Vallejo, Teresa Marrodán Ciordia, Jonathan Fernández-Suárez, Lucía Boix-Palop, Jordi Pedragosa, A Jover, Juan Sevilla Blanco, Fátima Galán‐Sánchez, Clara Natera Kindelán, Alfonso del Arco, Alberto Bahamonde-Carrasco, Alejandro Smithson Amat, David Vinuesa García, Carmen Rodríguez, Isabel María Reche Molina, Inés Pérez Camacho, Antonio Sánchez-Porto, Marcos Guzmán García, Berta Becerril Carral, Esperanza Merino, Inmaculada López-Hernández, Jesús Rodríguez‐Baño, Luis Eduardo López-Cortés,
Tópico(s): Streptococcal Infections and Treatments
2021 - Elsevier BV | International Journal of Antimicrobial Agents
I. Mazzeo, Víctor Gallego, L. Pérez, David S. Peñaranda, M. Jover, Juan F. Asturiano,
As no studies have been carried out to investigate the role of fatty acids in male European eel (Anguilla anguilla) maturation, the main aim of this work was to determine which fatty acids could play a central role in sexual maturation. To this end, European eel males were hormonally induced to sexual maturation and variations in fatty acid composition in muscle, liver, testis and milt were studied. Eels were injected weekly with hCG (Human Chorionic Gonadotropin) for 13 weeks and 10 eels per week ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2010 - Wiley | Journal of Applied Ichthyology
Isabel Ochando, Sara Jover‐Gil, Juan José Ripoll, Héctor Candela, Antonio Vera, Marı́a Rosa Ponce, Antonio Martínez‐Laborda, José Luis Micol,
Abstract Here, we describe how the semidominant, gain-of-function icu4-1 and icu4-2 alleles of the INCURVATA4 (ICU4) gene alter leaf phyllotaxis and cell organization in the root apical meristem, reduce root length, and cause xylem overgrowth in the stem. The ICU4 gene was positionally cloned and found to encode the ATHB15 transcription factor, a class III homeodomain/leucine zipper family member, recently named CORONA. The icu4-1 and icu4-2 alleles bear the same point mutation that affects the microRNA ...
Tópico(s): Plant Reproductive Biology
2006 - Oxford University Press | PLANT PHYSIOLOGY
Francisco Javier Jover Maestre, Juan Antonio López Padilla, Carmen Machado Yanes, M. Isabel Herráez Martín, Diego Rivera Núñeź, María Luisa Precioso Arévalo, Rafael Llorach Asunción,
Los trabajos arqueológicos que se llevan a cabo en el yacimiento de la Edad del Bronce de Terlinques (Villena, Alicante) han proporcionado un excepcional conjunto de husos o bobinas de hilo de junco.Éstos se hallaban almacenados en el interior de una habitación destruida por un violento incendio.El detenido estudio de estos singulares objetos y su proceso de análisis y restauración nos permite aproximamos, desde nuevas perspectivas, al conocimiento de la producción textil en las etapas iniciales ...
Tópico(s): Archaeological and Historical Studies
2001 - Spanish National Research Council | Trabajos de Prehistoria
Adrián Mora González, Antonio Delgado‐Huertas, Arsenio Granados, Francisco Contreras Cortés, Francisco Javier Jover Maestre, Juan Antonio López Padilla,
Tópico(s): Tree-ring climate responses
2016 - Springer Science+Business Media | Vegetation History and Archaeobotany
Juan Ángel Jover, César Hernández-Garcı́a, Inmaculada C. Morado, Emilio Vargas, Antonio Bañares, Benjamín Fernández‐Gutiérrez,
... and benefits of each option in individual patients. Juan Angel Jover MD, PhD*, Cesar Hernández-Garcia MD*, Inmaculada C. ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2003 - Wiley | Arthritis & Rheumatism
Juan Arizaga, Lluís Jover, Asier Aldalur, Juan F. Cuadrado, Alfredo Herrero, Carola Sanpera,
Stable isotopes analyses (SIAs) are an efficient tool to obtain a general insight into the diet of generalist consumers, such as the Yellow-legged Gull (Larus michahellis). Here we analysed δ13C, δ15N and δ34S values in feathers of chicks and adults, and used Bayesian triple-isotope mixing models to reconstruct the diet of a Yellow-legged Gull population breeding in the southeastern Bay of Biscay. Questions to test were (1) whether adults and chicks rely on different feeding resources during breeding ...
Tópico(s): Avian ecology and behavior
2013 - Elsevier BV | Marine Environmental Research
Francisco Marco‐Jiménez, David S. Peñaranda, L. Pérez, M.P. Viudes-de-Castro, Constantinos C. Mylonas, M. Jover, Juan F. Asturiano,
As part of a larger study on sperm quality and cryopreservation methods, the present study characterized the head morphometry of sharpsnout sea bream (Diplodus puntazzo) and gilthead sea bream (Sparus aurata) spermatozoa, using both scanning electron microscopy (SEM) and computer-assisted morphology analysis (ASMA). The latter method has been used rarely in fish and this is its first application on sharpsnout sea bream and gilthead sea bream spermatozoa. Results obtained using SEM are expensive and ...
Tópico(s): Sperm and Testicular Function
2008 - Wiley | Journal of Applied Ichthyology
Carmen Cabezas, Ermengol Coma, Nuria Mora-Fernandez, Xintong Li, Montserrat Martínez, Francesc Fina-Avilés, Mireia Fàbregas, Eduardo Hermosilla, Angel Jover, Juan Carlos Contel, Yolanda Lejardi, Belén Enfedaque, Josep María Argimón, Manuel Medina, Daniel Prieto‐Alhambra,
Background: Spain began vaccinating priority groups against COVID-19 with BNT162b2 in late December 2020. We report associations of vaccination with COVID-19 infection, hospitalisation, and mortality among nursing home residents, nursing home staff, and healthcare workers. Methods: We analysed three cohorts of all nursing home residents, nursing home staff, and healthcare workers in Catalonia on 27 December 2020. Data were obtained from linked primary care, RT-PCR and lateral flow test, hospital, ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - RELX Group (Netherlands) | SSRN Electronic Journal
Amparo Ruı́z, Sergio Almenar, Miguel Jover Cerdá, Juan José Hidalgo, Alfonso Puchades, Antonio Llombart‐Bosch,
Ductal carcinoma in situ (DCIS) is a heterogeneous group of lesions that has been subdivided into three types: well differentiated (grade I), moderately differentiated (grade II), and poorly differentiated (grade III). Forty-five cases of DCIS were analyzed for image analysis: nuclear area, DNA ploidy, and vascularization in order to establish a more precise correlation between the histologic grade and these morphometric parameters. Our results confirm that the mean nuclear area, DNA ploidy, and microvessel ...
Tópico(s): Radiomics and Machine Learning in Medical Imaging
2002 - Wiley | The Breast Journal
Francisco Javier Jover Maestre, Juan Antonio López Padilla, Gonzalo García-Donato Layrón,
La investigación arqueológica desarrollada en lasúltimas décadas ha permitido evaluar que en los valles de los ríos Segura yVinalopó se dirimió el contacto entre dos sociedades de la Edad del Bronce dela península Ibérica: el grupo Argárico y el grupo del Prebético Meridional Valenciano.Las excavaciones realizadas en tres yacimientos de este ámbito –Terlinques,Cabezo Pardo y Cabezo Redondo– y las dataciones de radiocarbono obtenidaspermiten por primera vez evaluar la diacronía del proceso histórico ...
Tópico(s): Pleistocene-Era Hominins and Archaeology
2014 - University of Valencia | SAGVNTVM Papeles del Laboratorio de Arqueología de Valencia