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Jornais Acesso aberto

Edwin Morgan, (Dr) Judith Pinnington, David Marquand, Derek Parker, Aelfre, John Glare, D. A. N. Jones, Edward Norman, Kenneth Robinson, Peter Kemp, Keith Kyle, John Grigg, John Holstrom, Calum MacDonald, Martin Young, John Thompson, Hans Keller, Dennis Duncanson, T. M. Higham, Gavin Millar, David Wheeler, Evan Charlton, Stewart Trotter, Stephen Reno, Maire Messenger, Nick Barrett,

... 1933-75. By Stephen Spender. Macmillan £7.95 Fontana £1.50 Don Juan and Don Q The Second Ring of Power. By Carlos Castaneda. Hodder £4.95 Don Q. By Jose Lopez Portillo. James Clark £4.20 Evans Wolsey Hall ...

1978 - Gale Group | The Listener GDA

Artigo Acesso aberto

Flavia Bruna, Leonardo Romeo, Fiorella Campo Verde Arboccó, David Contador, Silvina Gómez, Flavia Santiano, Corina Verónica Sasso, Leila Zyla, Constanza M. López-Fontana, Juan Carlos Calvo, Rubén W. Carón, Virginia Pistone‐Creydt,

Tumor cells can interact with neighboring adipose tissue. We evaluated components present in human adipose explants from normal (hRAN) and kidney cancer (hRAT) tissue, and we evaluated the effects of conditioned media (CMs) from hRAN and hRAT on proliferation, adhesion and migration of tumor and non-tumor human renal epithelial cell lines. In addition, we evaluated the expression of AdipoR1, ObR, CD44, vimentin, pERK and pPI3K on cell lines incubated with CMs. hRAN were obtained from healthy operated ...

Tópico(s): Lymphoma Diagnosis and Treatment

2019 - Impact Journals LLC | Oncotarget

Artigo Acesso aberto Revisado por pares

Juan Fontana, Noelia López-Montero, Richard M. Elliott, José‐Jesús Fernández, Cristina Risco,

Viral factories are novel structures built by viruses in infected cells. During their construction organelles are recruited and build a large scaffold for viral replication and morphogenesis. We have studied how a bunyavirus uses the Golgi to build the factory. With the help of confocal and 3D ultrastructural imaging together with molecular mapping in situ and in vitro we have characterized a tubular structure that harbours the viral replication complexes in a globular domain. Numerous ribonucleoproteins ...

Tópico(s): Vector-borne infectious diseases

2008 - Wiley | Cellular Microbiology

Artigo Acesso aberto Revisado por pares

Juan Fontana, Carmen López‐Iglesias, Wen-Ping Tzeng, Teryl K. Frey, José‐Jesús Fernández, Cristina Risco,

Viral factories are complex structures in the infected cell where viruses compartmentalize their life cycle. Rubella virus (RUBV) assembles factories by recruitment of rough endoplasmic reticulum (RER), mitochondria and Golgi around modified lysosomes known as cytopathic vacuoles or CPVs. These organelles contain active replication complexes that transfer replicated RNA to assembly sites in Golgi membranes. We have studied the structure of RUBV factory in three dimensions by electron tomography and ...

Tópico(s): Virology and Viral Diseases

2010 - Elsevier BV | Virology

Artigo Acesso aberto Revisado por pares

Matías Ferrando, Flavia Bruna, Leonardo Romeo, David Contador, Daiana Lorena Moya-Morales, Flavia Santiano, Leila Zyla, Silvina Gómez, Constanza Matilde LópezFontana, Juan Carlos Calvo, Rubén W. Carón, Judith Toneatto, Virginia Pistone‐Creydt,

Abstract Tumor cells can interact with neighboring adipose cells and adipocyte dedifferentiation appears to be an important aspect of tumorigenesis. We evaluated the size of adipocytes in human adipose explants from normal (hRAN) and kidney cancer (hRAT); changes in the expression of WAT and BAT/beige markers in hRAN and hRAT; the expression of epithelial-mesenchymal transition (EMT) cell markers in human kidney tumor (786-O, ACHN and Caki-1); and non-tumor (HK-2) epithelial cell lines incubated with ...

Tópico(s): Cancer, Hypoxia, and Metabolism

2022 - Nature Portfolio | Scientific Reports

Artigo Acesso aberto Revisado por pares

Maximino Manzanera, Juan Jesús Narváez-Reinaldo, Cristina García‐Fontana, Juan Ignacio Vílchez, J. González‐López,

Arthrobacter koreensis 5J12A is a desiccation-tolerant organism isolated from the Nerium oleander rhizosphere. Here, we report its genome sequence, which may shed light on its role in plant growth promotion. This is believed to be the first published genome of a desiccation-tolerant plant growth promoter from the genus Arthrobacter.

Tópico(s): Legume Nitrogen Fixing Symbiosis

2015 - American Society for Microbiology | Genome Announcements

Artigo Acesso aberto Revisado por pares

Sabrina Johanna Fletcher, Paula Sacca, Mercedes Pistone-Creydt, Federico Coló, María Florencia Serra, Flavia Eliana Santino, Corina Verónica Sasso, Constanza Matilde LópezFontana, Rubén W. Carón, Juan Carlos Calvo, Virginia Pistone‐Creydt,

Adipose microenvironment is involved in signaling pathways that influence breast cancer. We aim to characterize factors that are modified: 1) in tumor and non tumor human breast epithelial cell lines when incubated with conditioned media (CMs) from human breast cancer adipose tissue explants (hATT) or normal breast adipose tissue explants (hATN); 2) in hATN-CMs vs hATT-CMs; 3) in the tumor associated adipocytes vs. non tumor associated adipocytes.We used hATN or hATT- CMs on tumor and non-tumor breast ...

Tópico(s): Glycosylation and Glycoproteins Research

2017 - BioMed Central | Journal of Experimental & Clinical Cancer Research

Artigo Acesso aberto Revisado por pares

Andrew J. Muir, Mitchell L. Shiffman, Atif Zaman, Boris Yoffe, Andrew de la Torre, Steven L. Flamm, Stuart C. Gordon, Paul Marotta, John M. Vierling, Juan Carlos Lopez‐Talavera, Kelly Byrnes-Blake, David Fontana, Jeremy A. Freeman, Todd Gray, Diana F. Hausman, Naomi Hunder, Eric Lawitz,

Interferon lambda 1 (IFN-lambda1) is a type III IFN that produces intracellular responses similar to those of IFN-alpha but in fewer cell types because of differences in the receptor distribution pattern, and this could potentially result in an improved safety profile. This was an open-label three-part study of patients with chronic hepatitis C virus (HCV) genotype 1 infection. Part 1 evaluated single-agent pegylated interferon lambda (PEG-IFN-lambda) at 1.5 or 3.0 microg/kg administered every 2 weeks ...

Tópico(s): Liver Disease Diagnosis and Treatment

2010 - Lippincott Williams & Wilkins | Hepatology

Artigo Acesso aberto Revisado por pares

Juan Ignacio Vílchez, Cristina García‐Fontana, Desireé Román-Naranjo, J. González‐López, Maximino Manzanera,

A collection of desiccation-tolerant xeroprotectant-producing microorganisms was screened for their ability to protect plants against drought, and their role as plant growth-promoting rhizobacteria was investigated in two different crops (tomato and pepper). The most commonly described biochemical mechanisms for plant protection against drought by microorganisms including the production of phytohormones, antioxidants and xeroprotectants were analyzed. In particular, the degree of plant protection ...

Tópico(s): Plant-Microbe Interactions and Immunity

2016 - Frontiers Media | Frontiers in Microbiology

Artigo Acesso aberto Revisado por pares

Alberto Fontana, Enrique J. Benito, Marie Martin, Nuria Sánchez-López, Ramón Alajarı́n, Juan J. Vaquero, Julio Álvarez‐Buílla, Stéphanie Lambel-Giraudet, Stéphane Léonce, Alain St. Pierre, Daniel H. Caignard,

Several new pyridazino[1′,6′:1,2]pyrido[3,4-b]indol-5-inium derivatives were synthesised from β-carboline derivatives and their cytotoxic activity and effect on the cell cycle were evaluated against L1210 cancer cells.

Tópico(s): Synthesis and Reactivity of Heterocycles

2002 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters

Artigo Acesso aberto Revisado por pares

Natalia Palmou‐Fontana, D. Martínez-López, Alfonso Corrales, Javier Rueda‐Gotor, Fernanda Genre, Susana Armesto, Marcos A. González‐López, Juan Carlos Quevedo-Abeledo, Virginia Portilla-González, Ricardo Blanco, José L. Hernández, Javier Llorca, Miguel Á. González‐Gay, Iván Ferraz‐Amaro,

Objective. Because the addition of carotid ultrasound (US) into composite cardiovascular (CV) risk scores has been found effective for identifying patients with inflammatory arthritis and high CV risk, we aimed to determine whether its use would facilitate the reclassification of patients with psoriatic arthritis (PsA) into the very high Systematic Coronary Risk Evaluation (SCORE) risk category and whether this might be related to disease features. Methods. This was a cross-sectional study involving ...

Tópico(s): Rheumatoid Arthritis Research and Therapies

2019 - The Journal of Rheumatology Publishing Company Limited | The Journal of Rheumatology

Artigo Acesso aberto Revisado por pares

Naga Chalasani, Cosme Manzarbeitia, Peter Ferenci, Wolfgang Vogel, Robert J. Fontana, Michael Voigt, Caroline A. Riely, Paul Martin, Lewis Teperman, James Jiao, Juan Carlos Lopez‐Talavera,

There is currently no effective treatment for recurrent hepatitis C after orthotopic liver transplantation (OLT). We therefore performed two randomized, controlled trials—a prophylaxis trial and a treatment trial—to evaluate the safety and efficacy of peginterferon alfa-2a in patients who had undergone OLT. The prophylaxis trial enrolled 54 patients within 3 weeks after OLT, and the treatment trial enrolled 67 patients 6 to 60 months after OLT. In each trial, patients were randomized to treatment ...

Tópico(s): Liver Disease and Transplantation

2005 - Lippincott Williams & Wilkins | Hepatology

Artigo Acesso aberto Revisado por pares

Rocío Galindo Zavala, Rosa Bou, Berta Magallares-López, Concepción Mir-Perelló, Natalia Palmou‐Fontana, Belén Sevilla‐Perez, Marta Medrano-San Ildefonso, María Isabel González, Almudena Román-Pascual, Paula Alcañiz-Rodríguez, Juan Carlos Nieto‐González, Mireia López-Corbeto, Jenaro Graña Gil,

Osteoporosis incidence in children is increasing due to the increased survival rate of patients suffering from chronic diseases and the increased use of drugs that can damage bones. Recent changes made to the definition of childhood osteoporosis, along with the lack of guidelines or national consensuses regarding its diagnosis and treatment, have resulted in a wide variability in the approaches used to treat this disease. For these reasons, the Osteogenesis Imperfecta and Childhood Osteoporosis ...

Tópico(s): Vitamin D Research Studies

2020 - BioMed Central | Pediatric Rheumatology

Artigo Revisado por pares

Iñigo González Mazón, Javier Rueda‐Gotor, Iván Ferraz‐Amaro, Fernanda Genre, Alfonso Corrales, Vanesa Calvo Rio, Natalia Palmou‐Fontana, Virginia Portilla, Javier Llorca, Cristina Mata, Vanesa Hernández-Hernández, Juan Carlos Quevedo-Abeledo, Carlos Rodríguez‐Lozano, Clementina López‐Medina, Lourdes Ladehesa-Pineda, Santos Castañeda, Esther Vicente, Cristina Fernández‐Carballido, María Paz Martínez-Vidal, David Castro Corredor, Joaquín Anino-Fernández, Diana Peiteado, Chamaida Plasencia‐Rodríguez, Maria Luz García-Vivar, E. Galíndez-Agirregoikoa, Esther Montes Pérez, Carlos Mario Fernández Díaz, Ricardo Blanco, Miguel Á. González‐Gay,

To compare the atherosclerosis disease burden between ankylosing spondylitis (AS) and non-radiographic (nr) axial spondyloarthritis (axSpA) and establish a model that allows to identify high-cardiovascular (CV) risk in axial spondyloarthritis patients.Cross-sectional study from the AtheSpAin cohort, a Spanish multicenter cohort aimed to study atherosclerosis in axSpA. Carotid ultrasound (US) was performed to determine the carotid intima-media wall thickness (cIMT) and detect the presence of carotid plaques. ...

Tópico(s): Rheumatoid Arthritis Research and Therapies

2021 - Elsevier BV | Seminars in Arthritis and Rheumatism

Artigo Acesso aberto Revisado por pares

María de Fátima Poza Vilches, Esther García González, Carmen Solís-Espallargas, Leticia Concepción Velasco Martínez, Abigail López-Alcarria, Ligia Isabel Estrada-Vidal, Rocío Jiménez-Fontana, Fátima Rodríguez Marín, María Puig Gutiérrez, Juan Carlos Tójar Hurtado, José Gutiérrez Pérez,

Purpose The purpose of this paper is to analyse the presence of the sustainable development goals (SDGs) proposed by the UN (2015) in university degrees within the fields of education, humanities and environmental sciences (ES) at Andalusian public institutions (Spain). Design/methodology/approach This paper shows an empirical analysis from a mixed methodological model on a total of 99 syllabi and training programs from nine different universities. The collection of information has been carried out ...

Tópico(s): Environmental Education and Sustainability

2021 - Emerald Publishing Limited | International Journal of Sustainability in Higher Education

Artigo Revisado por pares

Gastón López-Fontana, Juan Manuel Guglielmi, Rodrigo López-Fontana, Mariana Lis Hinojosa-Jury, Constanza M. López-Fontana, José Daniel López-Laur,

Objective: To analyze the perioperatory and short-oncological outcomes in 5 cases with CRPC M0 developed after pRT that underwent salvage laparoscopic RP (sLRP) and review the current evidence. Material and Methods: Perioperatory and oncological outcomes were prospectively analyzed. Inclusion criteria were patients that had received pRT and posteriorly presented with CRPC M0 in standard imagines and positron emission tomography MRI coline. Evidence was reviewed in PUBMED database. Results: No surgical ...

Tópico(s): Urologic and reproductive health conditions

2022 - SciELO | Archivos Españoles de Urología

Artigo Acesso aberto

Octavio A Castillo C, Gastón López-Fontana, René Henríquez D, Juan Bravo P,

Ureteral replacement with cecal appendixWe report two cases with ureteral lesions.A 34 years male with a residual retroperitoneal mass caused by a testicular cancer, that persisted after chemotherapy.During the surgical excision of the mass, the involvement of the right ureter was discovered.A 43 years old female with a left ureteral lesion secondary to radiation therapy and with a non-functioning contralateral kidney.In both cases a ureteral replacement with the cecal appendix was performed, without ...

Tópico(s): Abdominal Surgery and Complications

2012 - Elsevier BV | Revista Chilena de Cirugía

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Lucas M. Leveau, Mariana Lucia Bocelli, Sergio Gabriel Quesada-Acuña, César González‐Lagos, Pablo Gutiérrez Tapia, Gabriela Franzoi Dri, Carlos A. Delgado-V, Álvaro Garitano‐Zavala, Jackeline Campos, Yanina Benedetti, Rubén Ortega‐Álvarez, Antonio Isain Contreras Rodríguez, Daniela Souza López, Carla Suertegaray Fontana, Thaiane Weinert da Silva, Sarah Sandri Zalewski Vargas, Maria Cecília Barbosa de Toledo, Juan A. Sarquis, Alejandro R. Giraudo, Ada Lilian Echevarría, María Elisa Fanjul, María Valeria Martínez, Josefina Haedo, Luis Gonzalo Cano Sanz, Yuri A. Peña, Viviana Fernandez, Verónica Marinero, Vinícius Abilhôa, Rafael Amorin, Juan F. Escobar-Ibáñez, María Dolores Juri, Sergio R. Camín, Luis Marone, Augusto João Piratelli, Alexandre Gabriel Franchin, Larissa Crispim, Federico Morelli,

Background Urbanization will increase in the next decades, causing the loss of green areas and bird diversity within cities. There is a lack of studies at a continental scale analyzing the relationship between urban green areas, such as parks and cemeteries, and bird species richness in the Neotropical region. Bird diversity-environment relationships in urban parks and cemeteries may be influenced by latitudinal gradients or species-area relationships. However, the seasonal variation of species ...

Tópico(s): Urban Heat Island Mitigation

2022 - PeerJ, Inc. | PeerJ

Artigo Revisado por pares

Gastón López-Fontana, Juan Manuel Guglielmi, José Daniel López-Laur, Rodrigo López-Fontana,

espanolOBJETIVO: El manejo de la litiasis en anomalias renales es un desafio para el urologo debido a su infrecuencia; motivo por el cual, el objetivo es presentar nuestra experiencia en Cirugia Retrograda Intrarrenal (RIRS) en 4 casos con el uso del videoureterorrenoscopio flexible. MATERIAL Y METODOS: Analizamos retrospectivamente la base de datos de las primeras 100 RIRS por litiasis desde la incorporacion del videoureterorrenoscopio flexible (FLEX-X 8.4 Fr-STORZ®). Un total de 4 (4%) pacientes ...

Tópico(s): Pediatric Urology and Nephrology Studies

2020 - SciELO | Archivos Españoles de Urología

Artigo Acesso aberto

Rodrigo López Fontana, Juan Manuel Guglielmi, José Daniel, López Laur, G Fontana,

Objective: To report a case of forgotten intraabdominal renal tumor due to a self-performing retrieval bag failure, its management and lessons learned.Case Report: A 72 years old man underwent a laparoscopic partial nephrectomy due to 3cm renal tumor.A plastic self-performed retrieval bag was used for specimen extraction.Immediately after surgery, with the patient awake, the tumor was not inside the bag and this was broken at the bottom.A computer tomography showed a small mass next to the renorrhaphy; ...

Tópico(s): Renal and Vascular Pathologies

2019 - MedCrave Group | Urology & Nephrology Open Access Journal

Artigo Revisado por pares

Rodrigo López-Fontana, Gastón López-Fontana, Juan Manuel Guglielmi, José Daniel López-Laur, Mariana Lis Hinojosa Jury,

To report 2 cases of an extremely rare bladder tumor such as Cystitis Glandularis (CG) that were management by different strategies and review the current evidence.Both cases of 43 and 48 years reported the same lower urinary tract symptoms that simulated a malignant bladder tumor. Case 1 presented with an extensive tumor affecting the trigone and the left upper urinary tract; the second case presented a less extensive tumor also at the bladder trigone.The first patient required two bladder tumor ...

Tópico(s): Urologic and reproductive health conditions

2022 - SciELO | Archivos Españoles de Urología

Artigo Acesso aberto Revisado por pares

James M. Clay, Bárbara D. Fontana, Cristina Proserpio, Eduardo J. Fernández, Ella Pagliarini, Fernando De Carvalho Lopes, José Antonio López‐Moreno, Juan J. Canales, Louise Loyant, Ravid Doron, Lorenzo D. Stafford, Matthew O. Parker,

Background: We aimed to assess whether stress, boredom, drinking motives, and/or inhibitory control were related to alcohol use during a period of social isolation.Method: Analyses were carried out on questionnaire data (N = 337) collected during the first wave of the COVID-19 pandemic (7 April–3 May 2020). We first assessed changes in drinking behavior, stress and boredom. We then regressed drinking behavior on drinking motives, inhibitory control, stress, and boredom. We also investigated interactions ...

Tópico(s): Behavioral Health and Interventions

2022 - Taylor & Francis | Addiction Research & Theory

Artigo Acesso aberto

Fontana Gastón López, Fontana Rodrigo López, Guglielmi Juan Manuel, Bellesty Pedro, López Laur José Daniel,

Background: Spontaneous Retroperitoneal Hemorrhage, named Wünderlich Syndrome (WS) is usually managed by emergency surgeons with a conventional laparotomy. The aim is to report a patient with WS successfully treated by a laparoscopic approach avoiding open surgery. Methods: A 50-year-old female was diagnosed with WS hemodynamic instability and flank pain. After a normal CT scan that discarded visceral injuries and stabilized, the patient underwent a laparoscopic renal exploration. Results: Laparoscopic ...

Tópico(s): Renal cell carcinoma treatment

2023 - | Archives of Renal Diseases and Management

Artigo Revisado por pares

Juan Fontana, Noelia López Montero, Cristina Risco,

Las factorias virales son grandes estructuras construidas por componentes celulares y virales, donde los virus insertan los complejos macromoleculares necesarios para la replicacion del genoma y la morfogenesis de nuevas particulas virales. Estamos estudiando como las factorias se construyen aplicando varios metodos de microscopia electronica (ME). Nuestro objetivo es obtener mapas tridimensionales (3D) de estas estructuras complejas para estudiar como se forman los complejos replicativos, como se ...

Tópico(s): Genomics and Phylogenetic Studies

2007 - | Acta microscópica

Artigo Acesso aberto Revisado por pares

Trinidad González-Cejudo, Juan Miguel Villa-Suárez, María Ferrer-Millán, Francisco Andújar-Vera, Victoria Contreras-Bolívar, María Carmen Andreo-López, José Gómez-Vida, Luis Martínez-Heredia, Sheila González-Salvatierra, Tomás de Haro Muñoz, Cristina García‐Fontana, Manuel Muñoz‐Torres, Beatriz García-Fontana,

Since the prevalence of hypophosphatasia (HPP), a rare genetic disease, seems to be underestimated in clinical practice, in this study, a new diagnostic algorithm to identify missed cases of HPP was developed and implemented.

Tópico(s): Biochemical and Molecular Research

2023 - De Gruyter | Clinical Chemistry and Laboratory Medicine (CCLM)

Artigo Acesso aberto Revisado por pares

Natalia Palmou‐Fontana, Inmaculada Calvo, George Rego, A. Garcia-Rogero, Juan Carlos López Robledillo, B. P. Magallares López, P. Mesa del Castillo, E. Moreno, Carlos Redondo‐Figuero, Martina Steiner, Paz Collado,

... 197. Acknowledgements: NIL. Disclosure of Interests Natalia Palmou-Fontana: None declared, Inmaculada Calvo Speakers bureau: ABVIEE, NOVARTIS, JANSEN, GSK, GISELLA DIAZ CORDOVES REGO: None declared, ADRIAN GARCIA-ROGERO: None declared, Juan Carlos Lopez Robledillo: None declared, Berta Paula Magallares López: None ...

Tópico(s): Neurogenetic and Muscular Disorders Research

2023 - BMJ | Annals of the Rheumatic Diseases

Artigo Revisado por pares

Gastón López-Fontana, J.L. Álvarez-Ossorio, Juan Ignacio Ramos, Jesús Angel Viña Castiñeiras, J.L. Moyano, Octavio Castillo,

OBJETIVOS Presentar un caso de Papiloma Invertido (PI) ureteral con resolucion laparoscopica mediante la confeccion de Flap Boari. METODOS Presentamos un paciente varon de 30 anos de edad que consulto por hematuria asintomatica con unico hallazgo de defecto de replecion a nivel del tercio distal del ureter derecho. Debido a biopsia ureteroscopica no concluyente, se realizo una ureterectomia distal con neoimplante vesico-ureteral con tecnica de Flap Boari laparoscopico. El informe histopatologico ...

Tópico(s): Pediatric Urology and Nephrology Studies

2012 - SciELO | Archivos Españoles de Urología