Produção Nacional
Revisado por pares
Adalgisa Paula De Oliveira MARTINS, Maria de Fátima Bezerra, Sérgio Marques Júnior, André Brito, Júlio César de Andrade Neto, José Geraldo Bezerra Galvão Júnior, Dorgival Morais de Lima Júnior, Adriano Henrique do Nascimento Rangel,
The objective of this study was to correlate the gender and behavior of consumers of organic foods enriched with functional properties. The study was carried out by investigating the profile of organic and functional food consumers through the application of a questionnaire. A total of 1230 responses (of the questionnaire) were collected from people from all Brazilian states through social networks and e-mails following the snowball technique during the months of February and March 2017. The results ...
Tópico(s): Consumer Attitudes and Food Labeling
2019 - Sociedade Brasileira de Ciência e Tecnologia de Alimentos | Food Science and Technology
Produção Nacional
Revisado por pares
Priscila T. Rodrigues, Hugo O. Valdivia, Thaís C. de Oliveira, João M. P. Alves, Ana Maria Ribeiro de Castro Duarte, Crispim Cerutti-Junior, Julyana Cerqueira Buery, Cristiana Ferreira Alves de Brito, Júlio César de Souza, Zelinda Maria Braga Hirano, Marina Galvão Bueno, José Luiz Catão‐Dias, Rosely S. Malafronte, Simone Ladeia-Andrade, Toshihiro Mita, Ana María Santamaría, Igor Calzada, Indah Setyawati Tantular, Fumihiko Kawamoto, Leonie R. J. Raijmakers, Ivo Müeller, M. Andreína Pacheco, Ananías A. Escalante, Ingrid Felger, Marcelo U. Ferreira,
We examined the mitogenomes of a large global collection of human malaria parasites to explore how and when Plasmodium falciparum and P. vivax entered the Americas. We found evidence of a significant contribution of African and South Asian lineages to present-day New World malaria parasites with additional P. vivax lineages appearing to originate from Melanesia that were putatively carried by the Australasian peoples who contributed genes to Native Americans. Importantly, mitochondrial lineages ...
Tópico(s): Identification and Quantification in Food
2018 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Roseane Lieko Kubota, Marylene de Brito, Júlio César Voltolini,
Com objetivo de estimar o número mínimo de varreduras para coletar uma amostra representativa das larvas presentes em um grande recipiente, foram adicionadas 200 larvas de quarto estádio em um tambor de 80 litros de água. Com auxílio de peneira plástica, foram feitas dez varreduras em cada réplica do experimento. Os resultados indicaram que oito varreduras foram suficientes para coletar até 72% do total de 200 larvas de quarto estadio presentes no criadouro, ou seja, uma média de 143±1,97. A técnica ...
Tópico(s): Vector-Borne Animal Diseases
2003 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Olívia Diulen Costa Brito, Julio Cesar Batista Ferreira, Isabela Hernandes, Elizeu Junior da Silva, Cláudia Regina Dias‐Arieira,
Summary Nematodes of the genus Meloidogyne are one of the major limiting factors in tomato production and a challenging problem in organic systems. This study aimed to investigate the effect of agro-industrial wastes, their forms of application and doses on tomato plants inoculated with Meloidogyne javanica . First, nematodes were multiplied on tomato under glasshouse conditions to simulate a naturally infested environment. At 60 days after inoculation, plant shoots were removed, new seedlings were ...
Tópico(s): Plant Disease Management Techniques
2020 - Brill | Nematology
Produção Nacional
Revisado por pares
Marianni de Moura Rodrigues, Gisela Rita Alvarenga Monteiro Marques, Lígia Leandro Nunes Serpa, Marylene de Brito Arduíno, Júlio César Voltolini, Gerson Laurindo Barbosa, Valmir Roberto Andrade, Virgília Luna Castor de Lima,
Measure the populations of Ae. aegypti and Ae. albopictus adults according to sex and location inside or outside the residence, estimate Ae. aegypti female density per house and per resident, and test the association with abiotic factors.Adult mosquitoes were collected monthly with a hand net and portable electric catcher in the peridomiciliary and intradomiciliary premises of residences in an urban area with ongoing dengue transmission in the municipality of São Sebastião, Brazil, from February ...
Tópico(s): Insect Pest Control Strategies
2015 - BioMed Central | Parasites & Vectors
Produção Nacional
Revisado por pares
Débora Cristina Sampaio de Assis, Thaís Michelle Liziere da Silva, Rommel Furst Brito, Lorraine Cássia Gonçalves da Silva, William Gustavo Lima, Júlio César Moreira Brito,
We conducted a systematic review and meta-analysis to determine the rate of contamination in bovine meat and meat products with Shiga toxin-producing Escherichia coli (STEC) in Brazil over the last fifteen years. Data were obtained from online databases in February 2020, and 25 papers were selected from 1036 articles identified in the literature search and 13 articles from gray literature, totaling 4286 samples analyzed. The overall rate of STEC was estimated to be 1% in Brazil. The highest rate ( ...
Tópico(s): Food Safety and Hygiene
2020 - Elsevier BV | Meat Science
Produção Nacional
Revisado por pares
Anderson Antônio Carvalho Alves, Lucas Tassoni Andrietta, Rafael Zinni Lopes, Fernando de Oliveira Bussiman, Fabyano Fonseca e Silva, Roberto Carvalheiro, Luiz F. Brito, Júlio César de Carvalho Balieiro, Lúcia Galvão de Albuquerque, Ricardo Vieira Ventura,
This study focused on assessing the usefulness of using audio signal processing in the gaited horse industry. A total of 196 short-time audio files (4 s) were collected from video recordings of Brazilian gaited horses. These files were converted into waveform signals (196 samples by 80,000 columns) and divided into training ( N = 164) and validation ( N = 32) datasets. Twelve single-valued audio features were initially extracted to summarize the training data according to the gait patterns ( Marcha Batida —MB ...
Tópico(s): Genetic and phenotypic traits in livestock
2021 - Frontiers Media | Frontiers in Animal Science
Produção Nacional
Revisado por pares
Júlio César Moreira Brito, Lucas Raposo Carvalho, Amanda Neves de Souza, Guilherme Carneiro, Paula Prazeres Magalhães, Luiz M. Farias, Natália Rocha Guimarães, Rodrigo M. Verly, Jarbas M. Resende, Maria Elena de Lima,
The biological activity of antimicrobial peptides and proteins is closely related to their structural aspects and is sensitive to certain post-translational modifications such as glycosylation, lipidation and PEGylation. However, PEGylation of protein and peptide drugs has expanded in recent years due to the reduction of their toxicity. Due to their size, the PEGylation process can either preserve or compromise the overall structure of these biopolymers and their biological properties. The antimicrobial ...
Tópico(s): Chemical Synthesis and Analysis
2022 - Frontiers Media | Frontiers in Molecular Biosciences
Produção Nacional
Revisado por pares
Rafael Shinji Akiyama Kitamura, Maiara Vicentini, Maiara Carolina Perussolo, Juliana Roratto Lirola, Camilla Freitas Cirilo dos Santos, Júlio César Moreira Brito, Marta Margarete Cestari, Maritana Mela Prodócimo, Marcelo Pedrosa Gomes, Helena Cristina Silva de Assis,
Ciprofloxacin (Cipro) is commonly detected in water worldwide, however, the ecotoxicological effects to aquatic biota is still not fully understood. In this study, using multiple biomarkers, it was investigated sublethal effects of short-term exposure to Cipro concentrations (1, 10 and 100 μg.L-1) in the Neotropical catfish Rhamdia quelen compared to non-exposure treatment (Control). After 96 h of exposure, the fishes were anesthetized for blood collection to hematological and genotoxicity biomarkers ...
Tópico(s): Aquaculture disease management and microbiota
2022 - Elsevier BV | Environmental Pollution
Produção Nacional
Revisado por pares
William Gustavo Lima, Júlio César Moreira Brito, Waleska Stephanie da Cruz Nizer,
Tópico(s): Nosocomial Infections in ICU
2020 - Elsevier BV | Medical Hypotheses
Produção Nacional
Revisado por pares
William Gustavo Lima, Júlio César Moreira Brito, Bárbara Gatti Cardoso, Valbert Nascimento Cardoso, Magna Cristina de Paiva, Maria Elena de Lima, Simone Odília Antunes Fernandes,
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2020 - Springer Science+Business Media | European Journal of Clinical Microbiology & Infectious Diseases
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Júlio César Moreira Brito, Daiane Cristina Rocha, Mário Antônio Navarro-Silva, Philippe Juneau,
We investigated individual and combined effects of environmentally representative concentrations of amoxicillin (AMX; 2 μg l-1), enrofloxacin (ENR; 2 μg l-1), and oxytetracycline (OXY; 1 μg l-1) on the aquatic macrophyte Lemna minor. While the concentrations of AMX and ENR tested were not toxic, OXY decreased plant growth and cell division. OXY induced hydrogen peroxide (H2O2) accumulation and related oxidative stress through its interference with the activities of mitochondria electron transport chain ...
Tópico(s): Pesticide and Herbicide Environmental Studies
2020 - Elsevier BV | Ecotoxicology and Environmental Safety
Júlio César Moreira Brito, William Gustavo Lima, Bárbara Gatti Cardoso, Daniela Carolina Simião, Juliana Mendes Amorim, Cristine de Araujo Silva,
Introduction: COVID-19 is a viral disease that has affected almost 21 million people worldwide. The lethality and considerable morbidity, high contagion and lack of specific drugs against COVID-19, has generated fear enhancing the habit of self-medication by Brazilian people. Objectives: This review aims to address critical issues related to the irrational use of medicines and medicinal plants against infection caused by the novel coronavirus. Results: The placement of fake news on social media, ...
Tópico(s): Healthcare Regulation
2020 - | Brazilian Journal of Health and Pharmacy
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Davi Santos Tavares, Vinícius Sobrinho Richardi, Raizza Zorman Marques, Natalia Wistuba, Júlio César Moreira Brito, Patrícia Soffiatti, Bruno Francisco Sant'Anna‐Santos, Mário Antônio Navarro-Silva, Philippe Juneau,
The co-occurrence of aquatic contaminants, such as antibiotics and herbicides, has motivated investigations into their interactive effects on aquatic organisms. We examined the combined effects of environmental concentrations of the antibiotic Enrofloxacin (Enro; 0–2.25 μg l−1) and Roundup OriginalDI (Roundup®; 0–0.75 μg active ingredient l−1), a glyphosate based-herbicide, on Elodea canadensis. Enro alone was not toxic, but the plants were highly sensitive to Roundup® whose toxicity is related to ...
Tópico(s): Constructed Wetlands for Wastewater Treatment
2019 - Elsevier BV | Environmental Pollution
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Júlio César Moreira Brito, Elisa Monteze Bicalho, Janaína Guernica Silva, Maria de Fátima Gomides, Queila Souza Garcia, Cléber Cunha Figueredo,
The physiological responses of the aquatic liverwort Ricciocarpus natans to ciprofloxacin (Cipro) exposure under different growth temperatures were investigated. Cipro appears to act as an inhibitor of mitochondrial Complex III by blocking the oxidation of quinol, resulting in the formation of hydrogen peroxide (H2O2). H2O2 accumulation upon Cipro exposure is responsible for decreased photosynthesis in plants. The amount of H2O2 in plants is kept under control by antioxidant enzymes, whose activities ...
Tópico(s): Lichen and fungal ecology
2018 - Elsevier BV | Chemosphere
Julio César Candelaria-Brito, Carlos Gutiérrez-Gutiérrez, Héctor Demetrio Bayarre-Vea, Claudia Acosta Cruz, Delia Margarita Montes de, Orestes Labrador-Mazón,
Introducción: la enfermedad renal crónica (ERC) genera numerosos gastos sanitarios y es altamente prevalente en ancianos.Objetivo: caracterizar pacientes adultos mayores con ERC residentes en el municipio Consolación del Sur, Cuba, en el período comprendido entre mayo y septiembre de 2014.Materiales y métodos: estudio observacional, descriptivo y transversal realizado en los consultorios del Programa Médico y Enfermera de la Familia 13, 14 y 42 en el Consejo Popular Entronque de Pilotos. El universo ...
Tópico(s): Health and Lifestyle Studies
2018 - | Revista Colombiana de Nefrología
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Cíntia Almeida Gonçalves, Júlio César Moreira Brito, ANNA MARY DA SILVA SOUZA, Fernanda Vieira da Silva Cruz, Elisa Monteze Bicalho, Cléber Cunha Figueredo, Queila Souza Garcia,
We investigate the physiological responses and antibiotic-uptake capacity of Lemna minor exposed to ciprofloxacin. Ciprofloxacin (Cipro) induced toxic effects and hormesis in plants by significantly modifying photosynthesis and respiration pathways. A toxic effect was induced by a concentration ≥1.05 mg ciprofloxacin l−1 while hormesis occurs at the lowest concentration studied (0.75 mg ciprofloxacin l−1). By impairing normal electron flow in the respiratory electron transport chain, ciprofloxacin ...
Tópico(s): Coastal wetland ecosystem dynamics
2017 - Elsevier BV | Journal of Hazardous Materials
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Júlio César Moreira Brito, Marília Mércia Lima Carvalho Carneiro, Mariem Rodrigues Ribeiro Cunha, Queila Souza Garcia, Cléber Cunha Figueredo,
We investigated the ability of the aquatic fern Azolla to take up ciprofloxacin (Cipro), as well as the effects of that antibiotic on the N-fixing process in plants grown in medium deprived (-N) or provided (+N) with nitrogen (N). Azolla was seen to accumulate Cipro at concentrations greater than 160 μg g −1 dry weight when cultivated in 3.05 mg Cipro l −1 , indicating it as a candidate for Cipro recovery from water. Although Cipro was not seen to interfere with the heterocyst/vegetative cell ratios, the ...
Tópico(s): Aquatic Ecosystems and Phytoplankton Dynamics
2017 - Elsevier BV | Environmental Pollution
Produção Nacional
Revisado por pares
Mônica Maria Souza de Oliveira, Júlio César Moreira Brito, Tânia A. T. Gomes, Beatriz E.C. Guth, M. J. Vieira, Zita V. Furtado Naves, Tânia Vaz, Kinue Irino,
The prevalence, serotypes and virulence profiles of Shiga toxin-producing Escherichia coli (STEC) were investigated in 205 healthy beef and dairy cattle, and 106 goats reared in the southeastern region of Minas Gerais State, Brazil. The prevalence of STEC was 57.5% (61/106) in goats, 39.2%, (40/102) in beef cattle and 17.5% (18/103) in dairy cattle. Among the 514 STEC isolates, 40 different serotypes were found and some of them were identified in a specific host. STEC isolates harboring stx1 corresponded ...
Tópico(s): Salmonella and Campylobacter epidemiology
2008 - Elsevier BV | International Journal of Food Microbiology
Produção Nacional
Revisado por pares
Rafael Shinji Akiyama Kitamura, Júlio César Moreira Brito, Helena Cristina Silva de Assis, Marcelo Pedrosa Gomes,
Tópico(s): Aquatic Ecosystems and Phytoplankton Dynamics
2022 - Springer Science+Business Media | Environmental Science and Pollution Research
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Júlio César Moreira Brito, Fábio Vieira, Rafael Shinji Akiyama Kitamura, Philippe Juneau,
This study investigated the occurrence and risk assessment of ten pharmaceutical products and two herbicides in the water of rivers from the Doce river watershed (Brazil). Of the 12 chemicals studied, ten (acyclovir, amoxicillin, azithromycin, ciprofloxacin, enrofloxacin, fluoxetine, erythromycin, sulfadiazine, sulfamethoxazole, glyphosate and aminomethylphosphonic acid) had a 100% detection rate. In general, total concentrations of all target drugs ranged from 4.6 to 14.5 μg L −1 , with fluoroquinolones ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2022 - Frontiers Media | Frontiers in Environmental Science
Produção Nacional
Revisado por pares
William Gustavo Lima, Rosângela Santos Pereira, Waleska Stephanie da Cruz Nizer, Júlio César Moreira Brito, Isabella Piassi Dias Godói, Valbert Nascimento Cardoso, Simone Odília Antunes Fernandes, Jaqueline Maria Siqueira Ferreira,
Tópico(s): Viral Infections and Vectors
2021 - Springer Science+Business Media | Archives of Virology
Produção Nacional
Revisado por pares
Raizza Zorman Marques, Natalia Wistuba, Júlio César Moreira Brito, Vinícius Bernardoni, Daiane Cristina Rocha, Marcelo Pedrosa Gomes,
The increasing use of antibiotics in animal production has become an emergent environmental problem. The large percentages of applied antibiotic doses eliminated in animal excrement often end up contaminating water resources, which are then used for irrigation - compromising agricultural production and/or food security. Here, we evaluated the effects of crop irrigation with water artificially contaminated by enrofloxacin (10 μg l
Tópico(s): Advanced oxidation water treatment
2021 - Elsevier BV | Ecotoxicology and Environmental Safety
Produção Nacional
Revisado por pares
Júlio César Moreira Brito, William Gustavo Lima, Lídia Pereira Barbosa Cordeiro, Waleska Stephanie da Cruz Nizer,
Viral infections of the lower respiratory tract are considered a public health problem. They affect millions of people worldwide, causing thousands of deaths, and are treated with expensive medicines, such as antivirals or palliative measures. In this study, we conducted a systematic review to describe the use of quercetin‐type flavonols against lower respiratory tract viruses and discussed the preclinical impact of this approach on different signs and clinical mechanisms of infection. The systematic ...
Tópico(s): Herbal Medicine Research Studies
2021 - Wiley | Phytotherapy Research
Produção Nacional
Revisado por pares
Marcelo Pedrosa Gomes, Daiane Cristina Rocha, Júlio César Moreira Brito, Davi Santos Tavares, Raizza Zorman Marques, Patrícia Soffiatti, Bruno Francisco Sant'Anna‐Santos,
Chemicals used to assure agricultural production and the feasibility of planting sites often end up in bodies of water used for crop irrigation. In a pot study, we investigated the consequences associated with the irrigation of maize with water contaminated by ciprofloxacin (Cipro; 0, 0.2, 0.8, 1.4 and 2.0 μg l-1) and/or glyphosate (0, 5, 25 and 50 mg l-1) on yields and food safety. Glyphosate in concentrations ≥25 mg l-1 prevented plant establishment, regardless of Cipro presence. Evaluations made ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2020 - Elsevier BV | Ecotoxicology and Environmental Safety
Produção Nacional
Revisado por pares
William Gustavo Lima, Júlio César Moreira Brito, Joerg Overhage, Waleska Stephanie da Cruz Nizer,
The novel human coronavirus (SARS-CoV-2), the causative agent of COVID-19, has quickly become a threat to the public health and economy worldwide. Despite the severity of some cases, there are no current pathogen-specific antivirals available to treat the disease. Therefore, many studies have focused on the evaluation of the anti-SARS-CoV-2 activity of clinically available drugs. Here, we conducted a systematic review to describe the drug repositioning strategy against SARS-CoV-2 and to discuss the ...
Tópico(s): PARP inhibition in cancer therapy
2020 - Springer Science+Business Media | Archives of Virology
Produção Nacional
Revisado por pares
William Gustavo Lima, Júlio César Moreira Brito, Valbert Nascimento Cardoso, Simone Odília Antunes Fernandes,
Skin infections caused by methicillin-resistant Staphylococcus aureus (MRSA) require the development of new and effective topical antibiotics. In this context, melittin, the main component of apitoxin, has a potent antibacterial effect. However, little is known regarding the anti-inflammatory potential this peptide in infection models, or its ability to induce clinically important resistance. Here, we aimed to conduct an in-depth characterization of the antibacterial potential of melittin in vitro ...
Tópico(s): Biochemical and Structural Characterization
2020 - Elsevier BV | European Journal of Pharmaceutical Sciences
Produção Nacional
Revisado por pares
William Gustavo Lima, Ayslan Barra, Júlio César Moreira Brito, Waleska S.C. Nizer,
To the editor In December 2019 in Wuhan, Hubei province (China), pneumonia of unknown cause with rapid transmission capacity between humans emerged [1]. Posteriorly, the pathogen responsible by this pneumonia was identified such as a new positive-sense single-stranded RNA virus of the genus Betacoronavirus [severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)] and since then the disease has come to be called coronavirus disease 2019 (COVID-19) [2]. COVID-19 quickly spread to several countries, ...
Tópico(s): Blood properties and coagulation
2020 - Lippincott Williams & Wilkins | Blood Coagulation & Fibrinolysis
Produção Nacional
Revisado por pares
William Gustavo Lima, Júlio César Moreira Brito, Waleska Stephanie da Cruz Nizer,
The emergence of novel coronavirus (SARS‐CoV‐2) in 2019 in China marked the third outbreak of a highly pathogenic coronavirus infecting humans. The novel coronavirus disease (COVID‐19) spread worldwide, becoming an emergency of major international concern. However, even after a decade of coronavirus research, there are still no licensed vaccines or therapeutic agents to treat the coronavirus infection. In this context, apitherapy presents as a promising source of pharmacological and nutraceutical ...
Tópico(s): Insect and Pesticide Research
2020 - Wiley | Phytotherapy Research
Produção Nacional
Olívia Diulen Costa Brito, Isabela Hernandes, Júlio César Antunes Ferreira, Michelly Ragazzi Cardoso, Odair Alberton, Cláudia Regina Dias‐Arieira,
Maize (Zea mays L.) is one crop of major relevance in Brazil; however, nematodes are limiting factors in maize growth and productivity due to the difficulty to control them. Studies point out that arbuscular mycorrhizal fungi (AMF) increase plant tolerance to nematodes. Thus, the aim of this study was to assess the association between AMFs and Pratylenchus brachyurus in maize growth. Six AMF species (Rhizophagus clarus, Claroideoglomus etunicatum, Gigaspora rosea, G. margarita, Scutellospora calospora, ...
Tópico(s): Mycorrhizal Fungi and Plant Interactions
2018 - Instituto de Investigaciones Agropecuarias, INIA | Chilean journal of agricultural research