Toshihiko Tashiro, Junji Ito, Ryung-Bo Sim, Kou Miyazawa, Etsuo Hamada, Keio Toi, Hisayoshi Kobayashi, Tomoyasu Ito,
... on MgO Surface. Characterization of Adsorbed SpeciesToshihiko Tashiro, Junji Ito, Ryung-Bo Sim, Kou Miyazawa, Etsuo Hamada, Keio ...
Tópico(s): Ammonia Synthesis and Nitrogen Reduction
1995 - American Chemical Society | The Journal of Physical Chemistry
Shingo Iwano, Tohru Okada, Wataru Koike, Keiji Matsuo, Reiko Toya, Masahiro Yamazaki, Shinya Ito, Junji Ito, Shinji Naganwa,
The aims of this study were to determine interobserver variability in volume measurements of lung tumors (including part-solid and nonsolid types) using novel computer-aided diagnosis (CAD) tools and a machine learning approach and to determine the potential reasons for variability.In 60 consecutive patients with peripheral lung cancer, the three-dimensional volumes of nodules were measured using the perimeter method by an experienced chest radiologist. In addition, for the same patients, maximal ...
Tópico(s): Medical Imaging Techniques and Applications
2009 - Elsevier BV | Academic Radiology
Y. Takéuchi, Nobuhiko Haga, Junji Ito,
Abstract A monoclinic metastable phase of anorthite composition, CaAl 2 Si 2 O 8 , has been synthesized as an artificial product. Crystals are twinned mostly on a submicroscopic scale. In the cell whose dimensions are a = 8.228(1), b = 8.621(1), c = 4.827(1) Å, β = 90.00(5)°, there are two formula units. The space group is P 2 1 . The structure has been worked out with the minimum-function method based upon intensities measured on an automated diffractometer. Final atomic coordinates give an R of 0.06 with ...
Tópico(s): Crystal Structures and Properties
1973 - De Gruyter | Zeitschrift für Kristallographie - Crystalline Materials
Tetsuro Yasuda, Atsushi Araki, Takaaki Kubota, Junji Ito, Yuzuru Mikami, Jane Fromont, Jun’ichi Kobayashi,
Four new bromopyrrole alkaloids, nagelamides O (1) and P (2) and mukanadins E (3) and F (4), were isolated from three collections of Okinawan marine sponges of the genus Agelas. The structures and stereochemistry of 1−4 were elucidated on the basis of their spectroscopic data.
Tópico(s): Microbial Natural Products and Biosynthesis
2009 - American Chemical Society | Journal of Natural Products
Junji Ito, Akihiko Kosugi, Tsutomu Tanaka, Kouichi Kuroda, Seiji Shibasaki, Chiaki Ogino, Mitsuyoshi Ueda, Hideki Fukuda, Roy H. Doi, Akihiko Kondo,
We constructed a novel cell surface display system to control the ratio of target proteins on the Saccharomyces cerevisiae cell surface, using two pairs of protein-protein interactions. One protein pair is the Z domain of protein A derived from Staphylococcus aureus and the Fc domain of human immunoglobulin G. The other is the cohesin (Coh) and dockerin (Dock) from the cellulosome of Clostridium cellulovorans. In this proposed displaying system, the scaffolding proteins (fusion proteins of Z and Coh) ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2009 - American Society for Microbiology | Applied and Environmental Microbiology
Junji Ito, Hiroshi Moriyama, Seiichiro INOKUCHI, Noboru GOTO,
Morphological study of the lower limb muscles is necessary for the analysis of muscle function and its relation to the aging process. In this study, we measured the muscle weight and the muscle fiber morphometry (cross-sectional area and total number of muscle fibers at the muscular belly, and muscle fiber size) of the human lower limb in an adult Japanese cadaver (male, 58 years old). The results presented here can provide the normal control data to elucidate the aging process of the human lower ...
Tópico(s): Muscle Physiology and Disorders
2003 - Keiji Okajima | Okajimas Folia Anatomica Japonica
Junji Ito, Andrey R. Nikolaev, Marjolein Luman, Maartje F. Aukes, Chie Nakatani, Cees van Leeuwen,
According to a widely cited finding by Ellis and Stark (1978 Perception 7 575-581), the duration of eye fixations is longer at the instant of perceptual reversal of an ambiguous figure than before or after the reversal. However, long fixations are more likely to include samples of an independent random event than are short fixations. This sampling bias would produce the pattern of results also when no correlation exists between fixation duration and perceptual reversals. When an appropriate correction ...
Tópico(s): Face Recognition and Perception
2003 - SAGE Publishing | Perception
To discover the generic behaviors of dynamic networks, we study a coupled map system with variable coupling strength. It is found that this system spontaneously forms various types of network structure according to the parameter values. Depending on the synchronized or desynchronized motion of unit dynamics, the network structure can be either static or dynamic. The separation of units into two groups, one composed of units with a large number of outgoing connections and the other units with little ...
Tópico(s): Complex Network Analysis Techniques
2003 - American Physical Society | Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics
Takashi Adachi, Junji Ito, Kouji Kawata, Masahiro Kaya, Hiroki Ishida, Hiroshi Sahara, Yoji Hata, Chiaki Ogino, Hideki Fukuda, Akihiko Kondo,
A novel cell-surface display system was constructed in Aspergillus oryzae. Each of the five genes encoding the putative cell-wall-localized protein from the A. oryzae genome was cloned and these cell-surface anchor functions were examined by fusion to the C-terminal of the green fluorescent protein (GFP). Using the MP1 and CWP proteins as anchor proteins, GFP signals were strongly observed on the cell surface of recombinant A. oryzae. When these proteins were used as anchor proteins for cell-surface ...
Tópico(s): Fungal and yeast genetics research
2008 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Masahiko Kaya, Junji Ito, Atsushi Kotaka, Kengo Matsumura, Hiroki Bando, Hiroshi Sahara, Chiaki Ogino, Seiji Shibasaki, Kouichi Kuroda, Mitsuyoshi Ueda, Akihiko Kondo, Yoji Hata,
Tópico(s): Enzyme Production and Characterization
2008 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Yohei Takahashi, Takaaki Kubota, Junji Ito, Yuzuru Mikami, Jane Fromont, Jun’ichi Kobayashi,
Three new sesquiterpenoid quinones, nakijiquinones G–I (1–3), containing a different amino group derived from amino acids have been isolated from Okinawan marine sponges of the family Spongiidae, and the structures and relative stereochemistry of 1–3 were elucidated on the basis of the spectral data. Nakijiquinones G–I (1–3) showed modest cytotoxicity and inhibitory activity against HER2 kinase, while nakijiquinone H (2) exhibited antimicrobial activity.
Tópico(s): Synthetic Organic Chemistry Methods
2008 - Elsevier BV | Bioorganic & Medicinal Chemistry
Junji Ito, Hiroshi Sahara, Masahiko Kaya, Yoji Hata, Seiji Shibasaki, Koji Kawata, Saori Ishida, Chiaki Ogino, Hideki Fukuda, Akihiko Kondo,
The yeast Saccharomyces cerevisiae GRI-117-UK was transformed to either display or secrete β-glucosidase 1 (BGL1) from the koji mold, Aspergillus oryzae. The β-glucosidase activity of BGL1-displaying yeast strains reached 405.9 U/g dry cell mass after 72 h of cultivation in YPD medium. The optimal pH and temperature for BGL1 displayed on the cell surfaces of the yeast were 5.0 and 55 °C, while the optima for BGL1 secreted by the yeast were 4.0 and 55 °C. The displayed BGL1 was stable at higher pH compared ...
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2008 - Elsevier BV | Journal of Molecular Catalysis B Enzymatic
Takaaki Kubota, Atsushi Araki, Junji Ito, Yuzuru Mikami, Jane Fromont, Jun’ichi Kobayashi,
Two new bromopyrrole alkaloids, nagelamides M (1) and N (2), have been isolated from an Okinawan marine sponge Agelas species, and the structures and stereochemistry were elucidated from the spectroscopic data. Nagelamide M (1) is a novel bromopyrrole alkaloid possessing a 2-amino-octahydropyrrolo[2,3-d]imidazole ring with a taurine unit, while nagelamide N (2) is a new bromopyrrole alkaloid possessing a 2-amino-tetrahydroimidazole-4-one ring with a taurine unit and 3-(dibromopyrrole-2-carboxamido)propanoic ...
Tópico(s): Marine Toxins and Detection Methods
2008 - Elsevier BV | Tetrahedron
Soichiro Tabuchi, Junji Ito, Takashi Adachi, Hiroki Ishida, Yoji Hata, Fumiyoshi Okazaki, Tsutomu Tanaka, Chiaki Ogino, Akihiko Kondo,
A novel cell surface display system in Aspergillus oryzae was established by using a chitin-binding module (CBM) from Saccharomyces cerevisiae as an anchor protein. CBM was fused to the N or C terminus of green fluorescent protein (GFP) and the fusion proteins (GFP-CBM and CBM-GFP) were expressed using A. oryzae as a host. Western blotting and fluorescence microscopy analysis showed that both GFP-CBM and CBM-GFP were successfully expressed on the cell surface. In addition, cell surface display of triacylglycerol ...
Tópico(s): Glycosylation and Glycoproteins Research
2010 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Kengo Ohshita, Haruaki Ishiyama, Yohei Takahashi, Junji Ito, Yuzuru Mikami, Jun’ichi Kobayashi,
A series of stereoisomers for the azetidine ring of penaresidin B was synthesized and their cytotoxic and antimicrobial activities were evaluated. Among six synthetic isomers 1–6, isomers 4 and 5 showed relatively potent cytotoxic activity against A549 (lung) and HT29 (colon) tumor cells as well as antibacterial activity.
Tópico(s): Synthetic Organic Chemistry Methods
2007 - Elsevier BV | Bioorganic & Medicinal Chemistry
Kazunari Takeuchi, Tōru Yokoyama, Atsushi Ono, Takuya Numasawa, Kanichiro Wada, Gentaro Kumagai, Junji Ito, Kazumasa Ueyama, Satoshi Toh,
Study Design A radiographic study in 111 patients using radiographs was conducted. Objective To clarify whether the modified laminoplasty with C3 laminectomy preserving the semispinalis cervicis (SSC) inserted into C2 could maintain the postopertive range of motion (ROM) and sagittal alignment compared with conventional C3-C7 laminoplasty reattaching the muscle to C2. Summary of Background Data Intraoperative injury of the SSC is relevant to the significant loss of ROM and the malalignment after laminoplasty. ...
Tópico(s): Spinal Fractures and Fixation Techniques
2007 - Lippincott Williams & Wilkins | Journal of Spinal Disorders & Techniques
Junji Ito, Andrey R. Nikolaev, Cees van Leeuwen,
Phase patterns of human scalp alpha EEG activity show spontaneous transitions between different globally phase-synchronized states. We studied the dynamical properties of these transitions using the method of symbolic dynamics. We found greater predictability (deterministicity) and heterogeneity in the dynamics than what was expected from corresponding surrogate series in which linear correlations are retained. A possible explanation of these observations within the framework of chaotic itinerancy ...
Tópico(s): Chaos control and synchronization
2007 - Wiley | Human Brain Mapping
Ya-Ching Shen, Yuan‐Bin Cheng, Jun’ichi Kobayashi, Takaaki Kubota, Yohei Takahashi, Yuzuru Mikami, Junji Ito, Yun-Sheng Lin,
Extensive column chromatography of the ethanolic extract of the soft coral Cespitularia taeniata collected in Taiwan has resulted in the isolation of eight new nitrogen-containing verticillene diterpenes, designated cespitulactams D-K ( 1- 8), together with three known diterpenes, cespitulactams A ( 9) and B ( 10) and cespitularin F. In addition, one new derivative, 6- O-acetylcespitulactam F ( 11), was prepared from compound 3. The structures of these compounds were elucidated on the basis of spectroscopic ...
Tópico(s): Synthetic Organic Chemistry Methods
2007 - American Chemical Society | Journal of Natural Products
Junji Ito, Pedro Maldonado, Wolf Singer, Sonja Grün,
During natural vision, primates perform frequent saccadic eye movements, allowing only a narrow time window for processing the visual information at each location. Individual neurons may contribute only with a few spikes to the visual processing during each fixation, suggesting precise spike timing as a relevant mechanism for information processing. We recently found in V1 of monkeys freely viewing natural images, that fixation-related spike synchronization occurs at the early phase of the rate ...
Tópico(s): Photoreceptor and optogenetics research
2011 - Oxford University Press | Cerebral Cortex
Daisuke Katsuki, Ryo Ohmura, Takao Ebinuma, Hideo Narita,
... Matsushita (Hokkaido Branch, Suzuki Shoko Co., Sapporo Japan), Junji Ito (Ito Keiki Kogyosho, Co., Sapporo), Yoshie Takahashi (National ...
Tópico(s): Hydrocarbon exploration and reservoir analysis
2006 - Taylor & Francis | The Philosophical Magazine A Journal of Theoretical Experimental and Applied Physics
Shinsuke Nakahara, Akinori Kubo, Yuzuru Mikami, Junji Ito,
The synthesis of cribrostatin 6 (1), which shows good biological activity as a dark blue cancer cells growth inhibitor and a number of pathogenic bacteria and fungi, was achieved in two steps from 1-acetylaminomethyl-5,7-diethoxy-8-hydroxy-6-methylisoquinoline ( 14).The related compounds (8~11) were also synthesized, and the antimicrobial activities of 1 and its nine
Tópico(s): Marine Sponges and Natural Products
2006 - Elsevier BV | Heterocycles
Chie Nakatani, Junji Ito, Andrey R. Nikolaev, Pulin Gong, Cees van Leeuwen,
Abstract The attentional blink (AB) phenomenon occurs when perceivers must report two targets embedded in a sequence of distracters; if the first target precedes the second by 200-600 msec, the second one is often missed. We investigated AB by measuring dynamic cross-lag phase synchronization for 565 electrode pairs in 40-Hz-range EEG. Phase synchrony, on average, was higher in experimental conditions, where two targets are reported, than in control conditions, where only the second target is reported. ...
Tópico(s): Functional Brain Connectivity Studies
2005 - The MIT Press | Journal of Cognitive Neuroscience
Kazunari Takeuchi, Tōru Yokoyama, Shuichi Aburakawa, Akira Saitō, Takuya Numasawa, Tetsuya Iwasaki, Taito Itabashi, Akihiro Okada, Junji Ito, Kazumasa Ueyama, Satoshi Toh,
Results of C4-C7 laminoplasty with C3 laminectomy and C3-C7 laminoplasty were compared.To clarify prospectively whether the modified laminoplasty preserving the semispinalis cervicis inserted into C2 could reduce the axial symptoms compared with conventional laminoplasty reattaching the muscle to C2.Intraoperative damage of the semispinalis cervicis is relevant to the development of axial symptoms after laminoplasty. In C3-C7 laminoplasty, however, it is difficult to preserve the muscle insertion ...
Tópico(s): Spinal Fractures and Fixation Techniques
2005 - Lippincott Williams & Wilkins | Spine
Junji Ito, Andrey R. Nikolaev, Cees van Leeuwen,
Tópico(s): Functional Brain Connectivity Studies
2004 - Springer Science+Business Media | Biological Cybernetics
Junji Ito, Y. Fujita, Mitsuyoshi Ueda, Hideki Fukuda, Akihiko Kondo,
To improve the cellulolytic activity of a yeast strain displaying endoglucanase II (EGII) from the filamentous fungus Trichoderma reesei QM9414, the genes encoding the cellulose-binding domain (CBD) of EGII, cellobiohydrolase I (CBHI) and cellobiohydrolase II (CBHII) from T. reesei QM9414, were fused with the catalytic domain of EGII and expressed in Saccharomyces cerevisiae. Display of each of the recombinant EGIIs was confirmed using immunofluorescence microscopy. In the case of EGII-displaying yeast ...
Tópico(s): Enzyme Production and Characterization
2004 - American Chemical Society | Biotechnology Progress
Yasuya Fujita, Junji Ito, Mitsuyoshi Ueda, Hideki Fukuda, Akihiko Kondo,
ABSTRACT A whole-cell biocatalyst with the ability to induce synergistic and sequential cellulose-degradation reaction was constructed through codisplay of three types of cellulolytic enzyme on the cell surface of the yeast Saccharomyces cerevisiae . When a cell surface display system based on α-agglutinin was used, Trichoderma reesei endoglucanase II and cellobiohydrolase II and Aspergillus aculeatus β-glucosidase 1 were simultaneously codisplayed as individual fusion proteins with the C-terminal- ...
Tópico(s): Advanced Cellulose Research Studies
2004 - American Society for Microbiology | Applied and Environmental Microbiology
Formation of a layered structure is studied in a globally coupled map of chaotic units with a plastic coupling strength that changes depending on the states of units globally and an external input. In the parameter region characterized by weakly chaotic and desynchronized dynamics, units spontaneously form a hierarchical structure due to the influence of the input. This hierarchical structure is not fixed in time, and is successively reorganized. It is found that the distribution of lifetimes of ...
Tópico(s): Fractal and DNA sequence analysis
2000 - Elsevier BV | Neural Networks
Hidehiko Kodama, Junji Ito, Aiichiro Nagaki, Tetsuo Ohta, Isao Furukawa,
With 3,3′-bis(2-oxazolyl)-1,1′-bi-2-naphthols (BINOL-Box) synthesized from 1,1′-bi-2-naphthol (BINOL), the enantioselective addition of diethylzinc to aryl aldehydes proceeded smoothly to give secondary aryl alcohols in good yield with good enantioselectivity. Interestingly, the yields and enantioselectivities were affected by the mixing sequence of the reactants. Furthermore, the synthesis of both enantiomers of the addition products has been achieved using the same ligands by choosing achiral additives, ...
Tópico(s): Synthetic Organic Chemistry Methods
2000 - Wiley | Applied Organometallic Chemistry
Hidehiko Kodama, Junji Ito, Kazushige Hori, Tetsuo Ohta, Isao Furukawa,
New BINOL-derived ligands, 3,3′-bis(2-oxazolyl)-1,1′-bi-2-naphthols (BINOL-Box), bearing chiral bis-oxazoline at the 3,3′-carbons, were synthesized from commercially available 1,1′-bi-2-naphthol (BINOL). With the new ligands obtained, we found that asymmetric 1,3-dipolar cycloaddition reaction of N-benzylidenebenzylamine N-oxide (2) to 3-((E)-2-butenoyl)-1,3-oxazolidin-2-one (1) was catalyzed by BINOL-Box–scandium complexes to give isoxazolidine 3 in high yield with high diastereo- and enantioselectivity. ...
Tópico(s): Synthesis and Catalytic Reactions
2000 - Elsevier BV | Journal of Organometallic Chemistry
Junji Ito, Supriyo Roy, Y Liu, Ying Cao, M. Fletcher, Lu Liu, John D. Boughter, Sonja Grün, Detlef Heck,
Current evidence suggests that delta oscillations (0.5-4 Hz) in the brain are generated by intrinsic network mechanisms involving cortical and thalamic circuits. Here we report that delta band oscillation in spike and local field potential (LFP) activity in the whisker barrel cortex of awake mice is phase locked to respiration. Furthermore, LFP oscillations in the gamma frequency band (30-80 Hz) are amplitude modulated in phase with the respiratory rhythm. Removal of the olfactory bulb eliminates respiration- ...
Tópico(s): Photoreceptor and optogenetics research
2014 - Nature Portfolio | Nature Communications