Shinichi Maeno, Daijo Hashimoto, Toshiro Otani, Ko Masumoto, Yasuyuki Fukui, Makoto Nishiyama, Masayuki Ishikawa, Nobuyuki Fujita, Hiroya Kanagawa,
Tópico(s): Sports injuries and prevention
2009 - Springer Science+Business Media | Knee Surgery Sports Traumatology Arthroscopy
Takiko Shimada, Yoichi Wakita, Motoyasu Otani, Ko IBA,
A tobacco microsomal ω-3 fatty acid desaturase gene (NtFAD3) under the control of CaMV35S promoter was introduced into rice plants by the microprojectile-mediated transformation. The transgenic plants grew normally and showed high seed fertility and characteristics similar to those of non-transgenic plants. However, the fatty acid compositions in leaves, roots and seeds were modified by the transformation. The content of linoleic acid (18:2) was lower in the transgenic plants than in the non-transgenic ...
Tópico(s): Photosynthetic Processes and Mechanisms
2000 - Japanese Society for Plant Biotechnology | Plant Biotechnology
Shinichi Maeno, Daijo Hashimoto, Toshiro Otani, Ko Masumoto, Hideo Matsumoto, Hiroyuki Enomoto, Yasuo Niki, Itsuki Yuzawa, Yasuyuki Fukui, Masayuki Ishikawa, Nobuyuki Fujita, Masashi Okubo,
We propose a unique arthroscopic technique, the "hanger-lifting procedure." Unlike conventional arthroscopy, the space in which the arthroscope is placed is not a joint space filled with water but a subcutaneous space filled with air. The space is kept lifted by a semi-loop-shaped hanger and a retraction system by use of a wire. In general, arthroscopes are unable to be applied outside the joint because of the lack of a cavity. However, this method can provide extra-articular visualization of the ...
Tópico(s): Foot and Ankle Surgery
2008 - Elsevier BV | Arthroscopy The Journal of Arthroscopic and Related Surgery
Shinichi Maeno, Daijo Hashimoto, Toshiro Otani, Ko Masumoto, Nobuyuki Fujita, Seiji Saito,
We describe a novel operative technique for patellar fracture. The patient is placed in the supine position for setup of both an image intensifier and arthroscopy. After routine intra-articular inspection with an arthroscope, an extra-articular space including the prepatellar bursa is developed. The space is created with a lifting hanger applied from a portal wherein an arthroscope can then afford both intra- and extra-articular observation of the articular and bony surface of the patella. By use ...
Tópico(s): Total Knee Arthroplasty Outcomes
2013 - Elsevier BV | Arthroscopy Techniques
Daisei Eto, K. Watanabe, Hisafumi Saeki, Ken-Ichi Oinuma, Ko-ichi Otani, Megumi Nobukuni, Hatsumi Shiratori‐Takano, Hideaki Takano, Teruhiko Beppu, Kenji Uéda,
Desferrioxamines (DF's) are siderophores produced by some groups of bacteria. Previously, we discovered that DFE, produced by Streptomyces griseus, induced divergent developmental phenotypes in various Streptomyces isolates. In this study, we isolated bacteria whose phenotype was affected by the presence of 0.1 mM DFB from soil samples, and studied their phylogenetic position via 16 S rRNA gene-based analysis. Isolates belonging to Microbacterium grew only in the presence of DFB in the medium. DFB ...
Tópico(s): Enzyme-mediated dye degradation
2012 - Springer Nature | The Journal of Antibiotics
Shinya Okada, Yoshiro Ebihara, Motoshige Kudo, Hiromi Serizawa, Tohru Shimizu, Masako Otani, Ko Tsuji,
To ascertain the cytologic characteristics of solitary fibrous tumors of the pleura (SFTPs) on smear preparations.Fine needle aspiration cytology (FNAC) was initially attempted preoperatively in five cases, but the specimens were inappropriate for interpretation because only a few tumor cells were obtained. Therefore, scratch smears made at the time of operation were used. Papanicolaou and immunocytochemical staining was performed in all 10 cases, 2 of which were malignant.As expected, cellular tumors ...
Tópico(s): Sarcoma Diagnosis and Treatment
2001 - Karger Publishers | Acta Cytologica
Taishi Kayano, Yura Ko, Kanako Otani, T. Kobayashi, Motoi Suzuki, Hiroshi Nishiura,
Japan implemented its nationwide vaccination program against COVID-19 in 2021, immunizing more than one million people (approximately 1%) a day. However, the direct and indirect impacts of the program at the population level have yet to be fully evaluated. To assess the vaccine effectiveness during the Delta variant (B.1.617.2) epidemic in 2021, we used a renewal process model. A transmission model was fitted to the confirmed cases from 17 February to 30 November 2021. In the absence of vaccination, ...
Tópico(s): Vaccine Coverage and Hesitancy
2023 - Nature Portfolio | Scientific Reports
Taishi Kayano, Misaki Sasanami, T. Kobayashi, Yura K Ko, Kanako Otani, Motoi Suzuki, Hiroshi Nishiura,
BackgroundIn Japan, vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initiated on 17 February 2021, mainly using messenger RNA vaccines and prioritizing health care professionals. Whereas nationwide vaccination alleviated the coronavirus disease 2019 (COVID-19)-related burden, the population impact has yet to be quantified in Japan. We aimed to estimate the numbers of COVID-19 cases and deaths prevented that were attributable to the reduced risk among vaccinated ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - Elsevier BV | The Lancet Regional Health - Western Pacific
Yuzo Arima, Kazuhiko Kanou, Takeshi Arashiro, Yura K Ko, Kanako Otani, Yuuki Tsuchihashi, Takuri Takahashi, Reiko Miyahara, Tomimasa Sunagawa, Motoi Suzuki,
Coronavirus disease 2019 (COVID-19) has caused unprecedented global morbidity and mortality. Japan has faced three epidemic "waves" of COVID-19 from early 2020 through early 2021. Here we narratively review the three waves in Japan, describe the key epidemiologic features of COVID-19, and discuss lessons learned.We assessed publicly available surveillance data, routine surveillance reports, and other relevant sources-multiple indicators were monitored to improve interpretation of surveillance data. ...
Tópico(s): Data-Driven Disease Surveillance
2021 - Japan Medical Association | JMA Journal
Tokumitsu Ko, Hajime Otani, Hiroji Imamura, Kyoko Omori, Chiyoko Inagaki,
Na+/K + adenosinetriphosphatase (sodium pump) may play a key role in the prevention of reperfusion injury caused by Ca 2+ overload.The present study was undertaken to investigate the role of sodium pump activity in warm induction of cardioplegia combined with reperfusion of oxygenated cardioplegic solution.Isolated and perfused rat hearts were subjected to 15 minutes of normothermic ischemia to produce a model of severely failing ~The hearts then received myocardial preservation.Warm (37 ~ C) or cold (4 ~ ...
Tópico(s): Fuel Cells and Related Materials
1995 - Elsevier BV | Journal of Thoracic and Cardiovascular Surgery
Kengo Harato, Aiko Sakurai, Yutaka Kudo, Takeo Nagura, Ko Masumoto, Toshiro Otani, Yasuo Niki,
To date, the knee kinematics of a discoid lateral meniscus (DLM) has not been elucidated. The aim was to investigate the three-dimensional knee kinematics in knees with a DLM using gait analysis.Ten patients (mean: 14years) diagnosed with bilateral DLM and unilaterally symptomatic snapping as well as 10 healthy controls (mean: 23years) participated in the study. Each patient with a DLM had unilaterally snapping knee in full extension and deep flexion. The three-dimensional gait analysis was performed ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2016 - Elsevier BV | The Knee
Shinichi Maeno, Daijo Hashimoto, Toshiro Otani, Ko Masumoto, Catherine Hui,
The "coiling-up procedure" is a novel technique for extra-articular arthroscopy. A coil-shaped lifter is used to create the extra-articular working space, and a dry arthroscopy is performed. It can be combined with conventional intra-articular arthroscopy to enable direct vision from both inside and outside the joint. We have successfully used this technique to perform a vastus lateralis release in cases of painful bipartite patella. This is an innovative technique that offers the possibility of ...
Tópico(s): Shoulder Injury and Treatment
2010 - Elsevier BV | Arthroscopy The Journal of Arthroscopic and Related Surgery
Kenji Takagishi, Tetsuya Matsuura, Takashi Masatomi, Etsuo Chosa, Tsuyoshi Tajika, Mikihiko Watanabe, Tetsu Iwama, Toshiro Otani, Katsunori Inagaki, Hiroyasu Ikegami, Mitsuhiro Aoki, Ko Kato, Toru Okuwaki, Koichi Sairyo, Yasushi Kameyama, Akira Maeda, Moroe Beppu,
Despite recommendations on how to prevent baseball injuries in youths by the Japanese Society of Clinical Sports Medicine, shoulder and elbow pain still frequently occurs in young baseball players. We conducted a questionnaire survey among baseball players at elementary schools across the country to understand the practice conditions of players, examining the risk factors of shoulder and elbow pain in baseball players. The questionnaire survey was conducted among elementary school baseball players ...
Tópico(s): Sports injuries and prevention
2017 - Elsevier BV | Journal of Orthopaedic Science
Kengo Harato, Yasuo Niki, Yutaka Kudo, Aiko Sakurai, Takeo Nagura, T. Hasegawa, Ko Masumoto, Toshiro Otani,
Our purpose was to clarify the differences of three-dimensional knee kinematics in anterior cruciate ligament (ACL)-deficient patients between with and without meniscal injury using gait analysis.A total of 72 knees in 36 young athletes with primary and unilateral ACL injury, with a mean age of 22 years, participated. Gait analysis was done before surgery. According to the arthroscopic findings, patients were divided into two groups. The patients with an unstable meniscal tear were allocated to the ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2015 - Elsevier BV | The Knee
Tadatsugu Imamura, Mayuko Saito, Yura K Ko, Takeaki Imamura, Kanako Otani, Hiroki Akaba, Kota Ninomiya, Yuki Furuse, Reiko Miyahara, Eiichiro Sando, Ikkoh Yasuda, Naho Tsuchiya, Motoi Suzuki, Hitoshi Oshitani,
Background: Roles of children and adolescents in spreading coronavirus disease 2019 (COVID-19) in the community is not fully understood. Methods: We analyzed the data of 7,758 children and adolescents with COVID-19 and characteristics of secondary transmission generated by these cases using case information published by local governments. Ratio of pediatric and adolescent cases generating secondary transmission was calculated for various social settings. Results: The incidence of COVID-19 was 24. ...
Tópico(s): COVID-19 Clinical Research Studies
2021 - Frontiers Media | Frontiers in Pediatrics
Kijae Kim, Yasunobu Ando, Akira Sugahara, Seongjae Ko, Yuki Yamada, Minoru Otani, Masashi Okubo, Atsuo Yamada,
Electrochemical double-layer (EDL) capacitors operating at high charge/discharge rates are an important class of electrochemical energy storage devices. Aqueous EDL capacitors show great potential for use as inexpensive devices with much higher power; however, their energy density is severely limited by the narrow electrochemical window of water (1.23 V) and the small specific capacity of the electrodes. Here, we develop a high-voltage aqueous supercapacitor based on a highly concentrated Li+ aqueous ...
Tópico(s): Advanced Memory and Neural Computing
2019 - American Chemical Society | Chemistry of Materials
Yusuke Kobayashi, Takeshi Arashiro, Miyako Otsuka, Yuuki Tsuchihashi, Takuri Takahashi, Yuzo Arima, Yura Ko, Kanako Otani, Masato Yamauchi, Taro Kamigaki, Tomoko Morita‐Ishihara, Hiromizu Takahashi, Sana Uchikoba, Michitsugu Shimatani, Nozomi Takeshita, Motoi Suzuki, Makoto Ohnishi,
Objective: Monitoring the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is important due to concerns regarding infectivity, transmissibility, immune evasion and disease severity. We evaluated the temporal and regional replacement of previous SARS-CoV-2 variants by the emergent strains, Alpha and Delta. Methods: We obtained the results of polymerase chain reaction screening tests for variants conducted in multiple commercial laboratories. Assuming that all previous ...
Tópico(s): Viral Infections and Outbreaks Research
2022 - World Health Organization | Western Pacific surveillance response journal
Kengo Harato, Yasuo Niki, Takashi Toyoda, Yusaku Kamata, Ko Masumoto, Toshiro Otani, Yasunori Suda,
The TightRope RT (Arthrex, Naples, FL) is a suspensory device for anterior cruciate ligament reconstruction. However, there is a potential risk of the button being pulled too far off the lateral femoral cortex into the soft tissue because the adjustable loop is long. The purpose of this article is to present an easy and safe technique for self-flip. As to the preparation of the graft, we draw the first line in the loop of the TightRope RT at the same length as the femoral tunnel, and we draw the ...
Tópico(s): Sports injuries and prevention
2016 - Elsevier BV | Arthroscopy Techniques
Hajime Otani, Y. Kato, Tokumitsu Ko, Yusuke Sakurai, Kiyoshi Kagawa, Kenji Tanaka, M Fukunaka, Hiroji Imamura, Edward J. Cragoe,
The present study was designed to examine whether activation of Na+/H+ exchange and subsequent massive Ca2+ influx via Na+/Ca2+ exchange are involved in the pathogenesis of myocardial reperfusion injury. We tested the effects of 1 mM amiloride, which is known to inhibit both Na+/H+ and Na+/Ca2+ exchange, and 3 microM 5-(N-ethyl-N-isopropyl) amiloride (EIPA), which is known to act as a specific inhibitor against Na+/H+ exchange, on the incidence of ventricular arrhythmias, isovolumic left ventricular ...
Tópico(s): Electron Spin Resonance Studies
1991 - Japanese Circulation Society | Japanese Circulation Journal
Hiroto Kawano, Shigeki Yamada, Yoshiyuki Watanabe, Satoshi Ii, Tomohiro Otani, Hirotaka Ito, Ko Okada, Chifumi Iseki, Motoki Tanikawa, Shigeo Wada, M. Oshima, Mitsuhito Mase, Kazumichi Yoshida,
How do regional brain volume ratios and cerebral blood flow (CBF, mL/min) change with aging, and are there sex differences? This study aimed to comprehensively evaluate the relationships between regional brain volume ratios and CBF in healthy brains. The study participants were healthy volunteers who underwent three-dimensional T1-weighted MRI, time-of-flight MR angiography, and four-dimensional (4D) flow MRI between 2020 and 2022. The brain was automatically segmented into 21 brain subregions from ...
Tópico(s): Advanced MRI Techniques and Applications
2023 - Buck Institute for Research on Aging | Aging and Disease
Reiko Miyahara, Kosuke Tamura, Tomoko Kato, Mineko Nakazaki, Kanako Otani, Yura K Ko, Taro Kamigaki, Yuzo Arima, Hideki Tani, Kazunori Oishi, Motoi Suzuki,
To determine the effects of age and variants of concern on transmission of SARS-CoV-2, we analyzed infection rates among close contacts over 4 periods in Toyama Prefecture, Japan. Among household contacts, odds of infection were 6.2 times higher during the period of the Omicron variant than during previous periods, particularly among children and adolescents.
Tópico(s): COVID-19 and Mental Health
2023 - Centers for Disease Control and Prevention | Emerging infectious diseases
Yura K Ko, Yuki Furuse, Kota Ninomiya, Kanako Otani, Hiroki Akaba, Reiko Miyahara, Tadatsugu Imamura, Takeaki Imamura, Alex R. Cook, Mayuko Saito, Motoi Suzuki, Hitoshi Oshitani,
Super-spreading events caused by overdispersed secondary transmission are crucial in the transmission of COVID-19. However, the exact level of overdispersion, demographics, and other factors associated with secondary transmission remain elusive. In this study, we aimed to elucidate the frequency and patterns of secondary transmission of SARS-CoV-2 in Japan.
Tópico(s): SARS-CoV-2 detection and testing
2022 - Elsevier BV | International Journal of Infectious Diseases
Kengo Harato, Yasuo Niki, Masaki Nagashima, Ko Masumoto, Toshiro Otani, Yoshiaki Toyama, Yasunori Suda,
Discoid lateral meniscus with snapping phenomenon is a rare pathologic condition. The purpose of this article is to present an arthroscopic technique for the treatment of discoid lateral meniscus with snapping phenomenon. The patient is placed in the supine position for confirmation of snapping. As the patient's knee bends, it can be confirmed by arthroscopy that the posterior horn of the discoid lateral meniscus moves posteriorly and the central portion of the discoid lateral meniscus moves anteriorly ...
Tópico(s): Shoulder Injury and Treatment
2015 - Elsevier BV | Arthroscopy Techniques
Yukito Hagihara, Susumu Tsukamoto, Tadayuki Otani, Goro Arakane, Ko Matsuda,
Tópico(s): Metallurgy and Material Forming
2005 - Springer Science+Business Media | Welding in the World
Toshika Otani, Hiroki Yokoyama, Ko Hanai, Junnosuke Miura, Yasuko Uchigata, Tetsuya Babazono,
The incidence of end-stage renal disease (ESRD) in Japanese patients with type 1 diabetes mellitus (T1DM) was investigated regarding the association between mean HbA1c values during follow-up and the duration of follow-up/illness.The study includes 988 patients diagnosed at ages younger than 30 yr.These patients were initially examined between 1962 and 1999, and HbA1 and/ or HbA1c measurements were taken for at least 3 yr after 1980.The follow-up period was from the date of the first HbA1 or HbA1c ...
Tópico(s): Diabetes and associated disorders
2019 - Japanese Society for Pediatric Endocrinology | Clinical Pediatric Endocrinology
Yukito Hagiwara, Susumu Tsukamoto, Tadayuki Otani, Goro Arakane, Ko Matsuda,
Fracture path deviation (FPD) is often observed in the standard Charpy V-notch (STD-Cv) test on laser welded joint due to the steep gradient of hardness distribution. The side notched Charpy V-notch (SN-Cv) test is often used to avoid FPD. Fundamental study on the comparison between STD- and SN-Cv tests on laser welded joint for high strength ultra-fine grained steel and on base metal for conventional steels indicates that the results obtained from SN-Cv test gives higher transition temperature and ...
Tópico(s): Welding Techniques and Residual Stresses
2004 - The Iron and Steel Institute of Japan | Tetsu-to-Hagane
Koji Amano, Isseki Maeda, Hiroto Ishiki, Tomofumi Miura, Yutaka Hatano, Hiroaki Tsukuura, Tomohiko Taniyama, Yoshihisa Matsumoto, Yosuke Matsuda, Hiroyuki Kohara, Tatsuya Morita, Masanori Mori, Satoshi Inoue, Naosuke Yokomichi, Kengo Imai, Toshihiro Yamauchi, Akemi Shirado Naito, Yu Uneno, Akira Yoshioka, Shuji Hiramoto, Ayako Kikuchi, Tetsuo Hori, Hiromi Funaki, Keiko Tanaka, Kozue Suzuki, Tina Kamei, Yukari Azuma, Teruaki Uno, Jiro Miyamoto, Hirofumi Katayama, Hideyuki Kashiwagi, Eri Matsumoto, Kiyofumi Oya, Takeya Yamaguchi, Tomonao Okamura, Hoshu Hashimoto, Shunsuke Kosugi, Nao Ikuta, Yaichiro Matsumoto, Takashi Ohmori, Takehiro Nakai, Takashi Ikee, Yuto Unoki, Kazuki Kitade, Shu Koito, Nanao Ishibashi, Masaya Ehara, Kosuke Kuwahara, Shohei Ueno, Shunsuke Nakashima, Yuta Ishiyama, Akihiro Sakashita, Ryo Matsunuma, Hana Takatsu, Takashi Yamaguchi, Satoko Ito, Toru Terabayashi, Jun Nakagawa, Tetsuya Yamagiwa, Akira Inoue, Takuhiro Yamaguchi, Mitsunori Miyashita, Saran Yoshida, Yusuke Hiratsuka, Keita Tagami, Hiroaki Watanabe, Takuya Odagiri, Tetsuya Ito, Masayuki Ikenaga, Keiji Shimizu, Akira Hayakawa, Rena Kamura, Takeru Okoshi, Tomohiro Nishi, Kazuhiro Kosugi, Yasuhiro Shibata, Takayuki Hisanaga, Takahiro Higashibata, Ritsuko Yabuki, Shingo Hagiwara, Miho Shimokawa, Satoshi Miyaké, Junko Nozato, Tetsuji Iriyama, Keisuke Kaneishi, Mika Baba, Ayumi Okizaki, Yuki Watanabe, Yuko Uehara, Eriko Satomi, Kaoru Nishijima, Junichi Shimoinaba, Ryoichi Nakahori, Takeshi Hirohashi, Jun Hamano, Natsuki Kawashima, Takashi Kawaguchi, Megumi Uchida, Ko Sato, Yoichi Matsuda, Satoru Tsuneto, Sayaka Maeda, Yoshiyuki Kizawa, Hiroyuki Otani,
Summary Background & aims The benefits of artificial nutrition and hydration in patients with advanced cancer remain unknown. Therefore, we conducted a prospective study to evaluate effects of enteral nutrition (EN) and parenteral nutrition and hydration (PNH) on survival in palliative care units. Methods This study involved a secondary analysis of a multicenter cohort study. Data of primary nutritional administration routes during the first week after admission (oral intake, enteral tube feeding, parenteral ...
Tópico(s): Frailty in Older Adults
2020 - Elsevier BV | Clinical Nutrition
Bongho Kim, Sunghan Bae, H. Choi, S. Choi, N. Kawamura, R. Kitamura, H. S. Ko, Yasuhiro Kondo, T. Mibe, M. Otani, G.P. Razuvaev, E. Won,
A beam profile monitor (BPM) based on a microchannel plate has been developed for muon beams with low transverse momentum for the measurement of the muon anomalous magnetic moment and electric dipole moment at high precision, with capability of diagnosing muon beams of kinetic energy range from a few keV to 4 MeV. The performance of the BPM has been evaluated using a surface muon beam at J-PARC and additionally with an ultraviolet (UV) light source. It has been confirmed that the BPM has a dynamic ...
Tópico(s): Particle accelerators and beam dynamics
2018 - Elsevier BV | Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment
Naoya Otani, Koichi Tomita, Mifue Taminato, Kenji Yano, Ko Hosokawa,
Supplemental Digital Content is available in the text.
Tópico(s): Body Contouring and Surgery
2018 - Wolters Kluwer | Plastic & Reconstructive Surgery Global Open
Masanori Mori, Takashi Kawaguchi, Kengo Imai, Naosuke Yokomichi, Takashi Yamaguchi, Kozue Suzuki, Ryo Matsunuma, Hiroaki Watanabe, Isseki Maeda, Yuko Uehara, Tatsuya Morita, Satoshi Inoue, Naosuke Yokomichi, Kengo Imai, Tatsuya Morita, Masanori Mori, Hiroaki Tsukuura, Toshihiro Yamauchi, Akemi Shirado Naito, Yu Uneno, Akira Yoshioka, Shuji Hiramoto, Ayako Kikuchi, Tetsuo Hori, Yosuke Matsuda, Hiroyuki Kohara, Hiromi Fanaki, Keiko Tanaka, Kozue Suzuki, Tina Kamei, Yukari Azuma, Koji Amano, Teruaki Uno, Jiro Miyamoto, Hirofumi Katayama, Hideyuki Kashiwagi, Eri Matsumoto, Kiyofumi Oya, Takeya Yamaguchi, Tomonao Okamura, Hoshu Hashimoto, Shunsuke Kosugi, Nao Ikuta, Yaichiro Matsumoto, Takashi Ohmori, Takehiro Nakai, Takashi Ikee, Yuto Unoki, Kazuki Kitade, Shu Koito, Nanao Ishibashi, Masaya Ehara, Kosuke Kuwahara, Shohei Ueno, Shunsuke Nakashima, Yuta Ishiyama, Akihiro Sakashita, Ryo Matsunuma, Hana Takatsu, Takashi Yamaguchi, Satoko Ito, Toru Terabayashi, Jun Nakagawa, Tetsuya Yamagiwa, Akira Inoue, Takuhiro Yamaguchi, Mitsunori Miyashita, Saran Yoshida, Yusuke Hiratsuka, Keita Tagami, Hiroaki Watanabe, Takuya Odagiri, Tetsuya Ito, Masayuki Ikenaga, Keiji Shimizu, Akira Hayakawa, Rena Kamura, Takeru Okoshi, Isseki Maeda, Tomohiro Nishi, Kazuhiro Kosugi, Yasuhiro Shibata, Takayuki Hisanaga, Takahiro Higashibata, Ritsuko Yabuki, Shingo Hagiwara, Miho Shimokawa, Satoshi Miyaké, Junko Nozato, Hiroto Ishiki, Tetsuji Iriyama, Keisuke Kaneishi, Mika Baba, Tomofumi Miura, Yoshihisa Matsumoto, Ayumi Okizaki, Yuki Watanabe, Yuko Uehara, Eriko Satomi, Kaoru Nishijima, Junichi Shimoinaba, Ryoichi Nakahori, Takeshi Hirohashi, Jun Hamano, Natsuki Kawashima, Takashi Kawaguchi, Megumi Uchida, Ko Sato, Yoichi Matsuda, Yutaka Hatano, Satoru Tsuneto, Sayaka Maeda, Yoshiyuki Kizawa, Hiroyuki Otani,
Context Parenteral morphine is widely used for dyspnea of imminently dying cancer patients (terminal dyspnea). However, the efficacy of other opioids such as oxycodone remains largely unknown. Objectives To explore the efficacy of parenteral oxycodone vs. morphine by continuous infusion over 24 hours in cancer patients with terminal dyspnea. Methods This was a pre-planned subgroup analysis of a multicenter prospective observational study. Inclusion criteria were advanced cancer patients admitted ...
Tópico(s): Pain Management and Opioid Use
2020 - Elsevier BV | Journal of Pain and Symptom Management