Produção Nacional
Revisado por pares
Rafael Antunes Vieira, Rodrigo Duarte Seabra,
... Como objeto de investigação, foram avaliadas as interfaces KDE Plasma 5.22, Cinnamon, Gnome com alterações do Ubuntu 21. ... Desktop. Os resultados obtidos revelaram que a interface KDE Plasma 5.22 foi a que obteve a melhor usabilidade ...
Tópico(s): Green IT and Sustainability
2023 - Associação Sul-Rio-Grandense de Pesquisadores em História da Educação (ASPHE) | RENOTE
D. Biskamp, E. Schwarz, A. Zeiler, Antonio Celani, J. F. Drake,
Electron magnetohydrodynamic (EMHD) turbulence is studied in two- and three-dimensional (2D and 3D) systems. Results in 2D are particularly noteworthy. Energy dissipation rates are found to be independent of the diffusion coefficients. The energy spectrum follows a k−5/3 law for kde>1 and k−7/3 for kde<1, which is consistent with a local spectral energy transfer independent of the linear wave properties, contrary to magnetohydrodynamic (MHD) turbulence, where the Alfvén effect dominates ...
Tópico(s): Fluid Dynamics and Turbulent Flows
1999 - American Institute of Physics | Physics of Plasmas
Elena Fernandez Redondo, Joaquín Martínez‐López, Ramón García‐Sánz, María-Ángeles Montalbán, Pilar Martínez‐Sánchez, Bruno Paiva, María‐Victoria Mateos, Laura Rosiñol, Maria Luisa Martín, Rosa Ayala, Rafael Martínez, Javier López, Adrián Alegre, Joan Besalduch, Joan Bargay, MT Hernández, María Eugenia Sarasquete, Pedro Sánchez‐Godoy, M Callís, Manuela Fernández, Joan Bladé, Jesús F. San Miguel, Juan José Lahuerta,
... IGK) rearrangements K-VJ and Kappa deleting element (KDE). DHJ and light chain rearrangements detected at the diagnosis were used in the follow-up. The sensitivity of PCR was between 1/103 and 1/104 as Martínez P. et al previously published in BJH, 2008. Regarding MFC the following monoclonal antibody combinations (FITC/PE/PerCP-Cy5.5/APC) were used at the diagnosis to identify different aberrant plasma cells phenotypes which were used as patient-specific ...
Tópico(s): Glycosylation and Glycoproteins Research
2011 - Elsevier BV | Blood
Jihye Ha, Hyeonah Lee, Saeam Shin, Hyunsoo Cho, Haerim Chung, Ji Eun Jang, Soo‐Jeong Kim, June‐Won Cheong, Seung‐Tae Lee, Jin Seok Kim, Jong Rak Choi,
... Vκ-Jκ; IGKB: Vκ-Kde; and JκCκ intron-Kde).‡ NGS analysis was performed with the LymphoTrack IGH FR1 Assay and LymphoTrack IGK Assay (Invivoscribe Technologies).§ Conventional myelomas refer to myeloma with Ig with both heavy and light chain molecules. Open table in a new tab NGS, next-generation sequencing. To examine the correlation between plasma cell percentage and clonality positivity, an analysis was ...
Tópico(s): Glycosylation and Glycoproteins Research
2021 - Elsevier BV | Journal of Molecular Diagnostics
Waleed Alduaij, Laura K. Hilton, Muntadhar Al Moosawi, Susana Ben‐Neriah, Barbara Meissner, Merrill Boyle, Kelly Mekwunye, David W. Scott, Heather A. Leitch, Jeffrey W. Craig,
... no clonal peaks (data not shown), the Vk-Kde/intron-Kde reaction (tube B) identified a single prominent peak ... bp) length amplified by the Vk2f/Vk4/Vk5-Kde primer set,6 consistent with a clonal B-cell population (Vk-Kde 3, Figure 2A, B). The same peak was ... analysis of composite tumor components using IGK Vk-Kde/intron-Kde BIOMED-2 primer sets in (A) the cervical ... shown in the lower panel. The IGK Vk-Kde/intron-Kde reaction yields 3 discrete collections of PCR products ... and their anticipated PCR product size ranges: Vk-Kde 1: Vk1f/6/Vk7-Kde, 210-250 bp, ...
Tópico(s): Viral-associated cancers and disorders
2022 - Wolters Kluwer | HemaSphere
Charu Chaudhry, Matthew C. Weston, Peter Schuck, Christian Rosenmund, Mark L. Mayer,
... type and three mutants. The rate of desensitization (kdes) is fastest for wild type, ∼200-fold slower ... of desensitization relative to wild type (−RT ln kdes/kwt) for each mutant (symbol and error bars). ... produced progressively slower rates of onset of desensitization (kdes) with rank-order responses to 10 mM glutamate ... The most effective combination of mutations, -HERLK-, slowed kdes 190-fold compared with wild-type GluR6, producing ... 298 K for SE and SV experiments, respectively). kdes, kdeact, % des, and krec are the rates of ...
Tópico(s): Cellular transport and secretion
2009 - Springer Nature | The EMBO Journal
Wei Wang, Yi Ding, Andrew Campbell, Beverly C. Handy, L. Jeffrey Medeiros, Pei Lin,
... the lymph node revealed the kappa deleting element (kde), which led to inactivation of the IGK allele; ... dominant IGK clone from lymph node revealed the kde rearranged to the Jk-Ck intron (IGKintr-IGKdel, Fig. 4D). The rearrangement involving kde has been shown to inactivate the IGK allele ... heterogeneous population composed of lymphocytes, plasmacytoid lymphocytes and plasma cells. Similar to other haematopoietic diseases, however, clonal ...
Tópico(s): Lymphoma Diagnosis and Treatment
2019 - Elsevier BV | Pathology
Mark Screen, Per Harald Jonson, Olayinka Raheem, Johanna Palmio, Reijo Laaksonen, Terho Lehtimäki, Mario Sirito, Ralf Krahe, Peter Hackman, Bjarne Udd,
... array raw intensity signals were analyzed with Inforsense KDE version 2.0.4 (Inforsense, London, UK) by ...
Tópico(s): Mitochondrial Function and Pathology
2014 - Elsevier BV | American Journal Of Pathology
Caroline Cox, Michael H. Surgan,
... chapter35_.html [accessed 28 September 2006]. Google ScholarEverett KDE, Dickerson HW. 2003. Ichthyophthirius multifilis and Tetrahymena thermophila ...
Tópico(s): Insect and Pesticide Research
2006 - National Institute of Environmental Health Sciences | Environmental Health Perspectives
Andrey A. Komissarov, Peter A. Andreasen, Julie Støve Bødker, Paul Declerck, John Anagli, Joseph D. Shore,
... large{⇄}k1EIk−2\large{⇄}k2E∼I′kiamp;↗ksamp;↘kdE−I∗↓I∗+E Inhibitory pathwaySubstrate pathway(Eq. 1) ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2004 - Elsevier BV | Journal of Biological Chemistry
Jing Li, Jianguo Zhi, Michael Wenger, Nancy Valente, Jennifer Visich,
... initial value following the first infusion. The term Kdes represents the actual rate of change from the ... 577 mL/day), and the rate of change (Kdes) from the specific clearance (mediated by CD20) to ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2009 - Elsevier BV | Blood
... sets: IGHV-IGHJ, IGHD-IGHJ, IGKV-IGKJ, IGKV-KDE/intronRSS-KDE. The forward primer sets in IGHV target the ... the deletion event involves the κ deleting element (Kde) in the intron (intron-Kde), the initial IGK V-J rearrangement is preserved. ... genes have unproductive rearrangements and both undergo intron-Kde–mediated deletion, it is possible to find evidence ... rearrangements per cell, in addition to two intron-Kde rearrangements. In the second case, two IGKVJ rearrangements ... deletion events, one of which was a IGKV-Kde deletion which removes any VJ rearrangement(s) on ...
Tópico(s): Lymphoma Diagnosis and Treatment
2021 - Elsevier BV | Journal of Molecular Diagnostics
T. M. Abdalla, V. P. Lakhin, T. J. Schep, E. Westerhof,
... electron magnetohydrodynamics are studied numerically. In the range kde<1 the energy exhibits a direct cascade ...
Tópico(s): Fluid Dynamics and Turbulent Flows
2003 - American Institute of Physics | Physics of Plasmas
Javad Ghorbani, Peter D. Wentzell, Mohsen Kompany‐Zareh, Nematollah Omidikia,
... modulator (MPM) adsorption model parameters such as β, kdes,0, and Keq,0, were fitted to the ... 00 are calculated interquartile range (IQR) for β, kdes,0, and Keq,0, respectively. Finally, results show three and two outliers for β and kdes,0, respectively.
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2022 - Elsevier BV | Journal of Chromatography A
Jelena Palić, Annabelle Heier, Annika Lehmbecker, Wolfgang Baumgärtner, María Elena Turba,
... lambda light chain (IgL), and kappa deleting element (Kde). Differential diagnoses for the lymphoproliferative disease in this ...
Tópico(s): Platelet Disorders and Treatments
2022 - Wiley | Veterinary Clinical Pathology
Michaela Nováková, Aleš Janda, Marcin W. Włodarski, Martina Suková, Vít Campr, Markéta Žaliová, Eva Froňková, Elena Vodickova, Ondřej Zapletal, Jan Blatný, Kateřina Lejhancová, Dagmar Pospı́šilová, Zdena Černá, Tomáš Kuhn, Zuzana Zemanová, Jan Trka, Ondřej Hrušák, Jan Starý, Ester Mejstříková,
... were analyzed by FC. The level of intronRSS-Kde recombination excision circles (KREC) and T-cell receptor ...
Tópico(s): Cystic Fibrosis Research Advances
2014 - Elsevier BV | Blood
Giovanna Piras, Maria Monne, Antonella Uras, Laura Pilo, Luciana Arca, Maurizio Cucca, Angelo Palmas, Anna Calvisi, Annalisa Noli, Marco Murineddu, A. Gabbas,
... analysis. IGHV-J, IGHD-J, IGKV-J, IGKV-KDE, IGKJ-C-INTRON-KDE rearrangements were amplified by PCR and analyzed following ... and the 60% presented the non-productive IGKV-KDE and IGKJ-C-INTRON-KDE rearrangements. Parallel analysis of clonality pattern and chromosomal ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2007 - Elsevier BV | Blood
Lloyd Hutchinson, Jong Seo Lee, Bruce A. Woda, Ediz F. Cosar,
... in three multiplexed PCR reactions to target IGK, KDE and IGL rearrangements. Variable region (V) primers were ... FRIII: 29.7%/100%, IGK: 80.4%/100%, KDE: 25.0%/100%, and IGL: 35.1%/96.8%. The combination of IGH FRIII, IGK, and KDE detected 83.8% (31/37) vs 67.3% ( ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2016 - OMICS Publishing Group | Journal of Molecular Biomarkers & Diagnosis
E. Sokol, V I Vasilyev, Svetlana Smirnova, Т Н Сафонова, S G Palshina, Е Б Родионова, Н В Кокосадзе, А. М. Ковригина,
... Ig kappa chain rearrangements (Vκ-Jk and Vκ-KDE/Intron RSS-KDE) in 1 case. The latter patient didn9t have ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2015 - BMJ | Annals of the Rheumatic Diseases