Chung Koo Kim, Ilya Drozdov, Kazuhiro Fujita, J. C. Davis, I. Božović, T. Valla,
Angle-resolved photoemission spectroscopy (ARPES) is the key momentum-resolved technique for direct probing of the electronic structure of a material. However, since it is highly surface-sensitive, it has been applied to a relatively small set of complex oxides that can be easily cleaved in ultra-high vacuum. Here we describe a new multi-module system at Brookhaven National Laboratory (BNL) in which an oxide molecular beam epitaxy (OMBE) is interconnected with an ARPES and a spectroscopic-imaging scanning ...
Tópico(s): Copper-based nanomaterials and applications
2018 - Elsevier BV | Journal of Electron Spectroscopy and Related Phenomena
Sourin Mukhopadhyay, Rahul Sharma, Chung Koo Kim, Stephen Edkins, Mohammad Hamidian, Hiroshi Eisaki, Shin‐ichi Uchida, Eun-Ah Kim, Michael J. Lawler, A. P. Mackenzie, J. C. Davis, Kazuhiro Fujita,
The CuO$_2$ antiferromagnetic insulator is transformed by hole-doping into an exotic quantum fluid usually referred to as the pseudogap (PG) phase. Its defining characteristic is a strong suppression of the electronic density-of-states D(E) for energies |E|<$\Delta^*$, where $\Delta^*$ is the pseudogap energy. Unanticipated broken-symmetry phases have been detected by a wide variety of techniques in the PG regime, most significantly a finite Q density-wave (DW) state and a Q=0 nematic (NE) state. Sublattice- ...
Tópico(s): Magnetic properties of thin films
2019 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Giichi Misawa, Mohachi Motegi, Kazuhiro Fujita, Kanetoshi Hattori,
Tópico(s): Cognitive Abilities and Testing
1984 - Elsevier BV | Personality and Individual Differences
Shuzo Kawarazaki, Kazuhiro Fujita, Katsumi Yasuda, Yutaka Sasaki, Takao Mizusaki, Akira Hirai,
It is shown by a brief calculation that the method of anisotropy measurement of $\ensuremath{\gamma}$-ray emission from spin-polarized nuclei is a useful tool to investigate multiple-spin-modulation waves which have been suggested to exist in several kinds of materials but have not yet been proven by definitive experimental evidence. An application of this method is made for a fcc antiferromagnetic Mn-Ni alloy and the first direct experimental evidence for a triple-Q spin-density wave is given.
Tópico(s): Magnetic properties of thin films
1988 - American Physical Society | Physical Review Letters
Mikiko Uchigashima, Mai Saigusa, Hiroshi Yamashita, Shiro Míyake, Kazuhiro Fujita, Masahiro Nakajima, Motohiro NISHIJIMA,
An organic solvent-tolerant monoclonal antibody specific to aflatoxins B(1), B(2), G(1), G(2), and M(1) (AFB(1), AFB(2), AFG(1), AFG(2), and AFM(1)) was prepared. In an indirect competitive enzyme-linked immunosorbent assay, the half maximal inhibitory concentration (IC(50)) values were 1.9, 2.1, 2.1, 2.4, and 2.8 ng/mL for AFB(1), AFB(2), AFG(1), AFG(2), and AFM(1), respectively. Antibody reactivity was retained at 40% methanol concentration or at acetonitrile concentrations up to 40%. An immunoaffinity ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2009 - American Chemical Society | Journal of Agricultural and Food Chemistry
Jun Hosogi, Hideyuki Tanaka, Kazuhiro Fujita, Takashi Kuwabara, Shigeo Ikegawa, Norihiro Kobayashi, Nariyasu Mano, Junichi Goto,
Determination of estrogens in plasma is important in evaluation of effects of some anticancer drugs, such as aromatase inhibitors. However, as reported previously, high performance liquid chromatography–radio immunoassay (HPLC–RIA) and liquid chromatography–tandem mass spectrometry (LC–MS/MS) with chemical derivatization require complicated sample preparation. In this study, a highly sensitive and simple method for determination of estrone (E1), 17β-estradiol (E2) and estrone 3-sulfate (E1S) in human ...
Tópico(s): Pharmacological Effects and Assays
2009 - Elsevier BV | Journal of Chromatography B
Shigeharu Tsurumi, Yuichi Nakamura, Kazuhiro Maki, Mitsuhiro Omine, Kazuhiro Fujita, Takashi Okamura, Yoshiyuki Niho, Sachiko Hashimoto, Keiko Kanno, Kenshi Suzuki, Akira Hangaishi, Seishi Ogawa, Hisamaru Hirai, Kinuko Mitani,
Abstract Alterations of the N‐ras oncogene and p53 tumor suppressor gene have been demonstrated to play an important role in pathogenesis of hematological malignancies. We simultaneously investigated genetic lesions of both genes in bone marrow cells from 64 Japanese patients with myeloproliferative disorders (MPD), including polycythemia vera (PV), essential thrombocythemia (ET), and idiopathic myelofibrosis (MF), by direct sequencing analysis. No mutations of the N‐ras gene were detected in any cases. ...
Tópico(s): Eosinophilic Disorders and Syndromes
2002 - Wiley | American Journal of Hematology
Satoshi Kumagai, Masahiro Nakajima, Setsuko TABATA, Eiichi Ishikuro, Toshitsugu Tanaka, Hiroko Norizuki, Yuhki Itoh, Koji Aoyama, Kazuhiro Fujita, Shigemi Kai, T. Sato, Shingo Saito, N. Yoshiike, Yoshiko Sugita‐Konishi,
A survey was undertaken of aflatoxin B1 (AFB1), B2 (AFB2), G1 (AFG1), G2 (AFG2), ochratoxin A (OTA), and fumonisin B1 (FB1), B2 (FB2) and B3 (FB3) contamination of various retail foods in Japan during 2004–05. The mycotoxins were analysed by high-performance liquid chromatography (HPLC), liquid chromatography/mass spectrometry (LC/MS) or high-performance thin-layer chromatography (HPTLC). Aflatoxins (AFs) were detected in ten of 21 peanut butter and in 22 of 44 bitter chocolate samples; the highest level of ...
Tópico(s): Potato Plant Research
2008 - Taylor & Francis | Food Additives & Contaminants Part A
Kazuhiro Fujita, Yu Toyoshima, Shinsuke Uda, Yu-ichi Ozaki, Hiroyuki Kubota, Shinya Kuroda,
In cellular signal transduction, the information in an external stimulus is encoded in temporal patterns in the activities of signaling molecules; for example, pulses of a stimulus may produce an increasing response or may produce pulsatile responses in the signaling molecules. Here, we show how the Akt pathway, which is involved in cell growth, specifically transmits temporal information contained in upstream signals to downstream effectors. We modeled the epidermal growth factor (EGF)-dependent ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2010 - American Association for the Advancement of Science | Science Signaling
Koji Aoyama, Masahiro Nakajima, Setsuko TABATA, Eiichi Ishikuro, Toshitsugu Tanaka, Hiroko Norizuki, Yoshinori Itoh, Kazuhiro Fujita, Shigemi Kai, Toru Tsutsumi, Masanori Takahashi, Hiroki Tanaka, Seiichiro Iizuka, Motoki OGISO, Mamoru Maeda, Shigeaki Yamaguchi, Kei‐ichi Sugiyama, Yoshiko Sugita‐Konishi, Susumu Kumagai,
Between 2004 and 2007 we examined foods from Japanese retail shops for contamination with ochratoxin A (OTA) and fumonisins B(1), B(2), and B(3). A total of 1,358 samples of 27 different products were examined for OTA, and 831 samples of 16 different products were examined for fumonisins. The limits of quantification ranged from 0.01 to 0.5 microg/kg for OTA and 2 to 10 microg/kg for the fumonisins. OTA was detected in amounts higher than limits of quantification in wheat flour, pasta, oatmeal, rye, ...
Tópico(s): Listeria monocytogenes in Food Safety
2010 - Elsevier BV | Journal of Food Protection
Ryosuke Matsui, Kentaro Seto, Kazuhiro Fujita, Takahiro Suzuki, Atsuo Nakazaki, Susumu Kobayashi,
Tied back: The title reaction was observed when a silicon-tethered diene was treated with the Hoveyda–Grubbs second-generation catalyst. The structural requirements for the E-olefin-forming ring-closing metathesis, and the transition state leading to E olefin are discussed. This methodology will be useful in the synthesis of polyketides containing a pent-2-ene-1,5-diol unit.
Tópico(s): Model-Driven Software Engineering Techniques
2010 - Wiley | Angewandte Chemie International Edition
Tetsuo Inui, Kazuhiro Fujita, Masaru Kitano, Toshihiro Nakamura,
A simple method using solid-phase extraction combined with metal furnace atomic absorption spectrometry was developed for the determination of Cr(III) and Cr(VI) at sub-ppb levels in water. A 500-ml water sample was adjusted to pH 3 with nitric acid and then passed through an iminodiacetate extraction disk placed on a cation-exchange extraction disk at a flow rate of 20-40 ml min(-1) for concentrating Cr(III). The filtrate was adjusted to pH 10 with aqueous ammonia and then passed through an anion- ...
Tópico(s): Extraction and Separation Processes
2010 - Springer Nature | Analytical Sciences
J. F. Douglas, Hideaki Iwasawa, Zhe Sun, А. В. Федоров, M. Ishikado, T. Saitoh, Hiroshi Eisaki, Hiroshi Bando, Takeshi Iwase, A. Ino, Masashi Arita, K. Shimada, H. Namatame, M. Taniguchi, T. Masui, S. Tajima, Kazuhiro Fujita, Shin-ichi Uchida, Y. Aiura, D. S. Dessau,
The possibility that a pairing boson might act as the 'glue' to bind electrons into a Cooper pair in superconductors with a high critical temperature (T(c)) is being actively pursued in condensed-matter physics. Gweon et al. claim that there is a large and unusual oxygen-isotope effect on the electronic structure, indicating that phonons have a special importance in high-temperature superconductors. However, we are unable to detect this unusual oxygen-isotope effect in new data collected under almost ...
Tópico(s): Advanced Condensed Matter Physics
2007 - Nature Portfolio | Nature
Jian Zheng, Hyoe Takata, Keiko Tagami, Tatsuo Aono, Kazuhiro Fujita, Shigeo Uchida,
Tópico(s): Radioactive contamination and transfer
2011 - Elsevier BV | Microchemical Journal
Tomomi Kimura, Yoko Shibata, Keiko Yamauchi, Akira Igarashi, Sumito Inoue, Shuichi Abe, Kazuhiro Fujita, Yoichi Uosaki, Isao Kubota,
Tópico(s): Respiratory Support and Mechanisms
2011 - Springer Science+Business Media | Lung
Hiroyuki Ohtsuka, Kazuhiro Fujita, Hiroyuki Kobayashi,
The sex difference of fentanyl (CAS 990-73-8) pharmacokinetics was investigated after intravenous administration to male and female rats at a dose of 0.03 mg/kg. The plasma concentrations of fentanyl disappeared mono-phasically in both male and female rats. Plasma concentrations and pharmacokinetic parameters were not significantly different in male and female rats, but plasma concentrations of fentanyl in female rats were lower than those in male rats until 1 h after administration. The distribution ...
Tópico(s): Diet and metabolism studies
2011 - Thieme Medical Publishers (Germany) | Arzneimittelforschung
Yoshiko Sugita‐Konishi, Masahiro Nakajima, Setsuko TABATA, Eiichi Ishikuro, Toshitsugu Tanaka, Hiroko Norizuki, Yoshinori Itoh, Koji Aoyama, Kazuhiro Fujita, Shigemi Kai, Susumu Kumagai,
We conducted a survey of aflatoxin B1, B2, G1, and G2, ochratoxin A, and fumonisin B1, B2, and B3 contamination in various foods on the retail market in Japan in 2004 and 2005. The mycotoxins were analyzed by high-performance liquid chromatography, liquid chromatography–mass spectrometry, or high-performance thin-layer chromatography. Aflatoxins were detected in 10 of 21 peanut butter samples; the highest concentration of aflatoxin B1 was 2.59 μg/kg. Aflatoxin contamination was not found in corn ...
Tópico(s): Wheat and Barley Genetics and Pathology
2006 - Elsevier BV | Journal of Food Protection
Wataru Abe, Satoshi Isaka, Yuya Koike, Kazuhiko Nakano, Kazuhiro Fujita, Toshihiro Nakamura,
A simple and convenient x-ray fluorescence analysis procedure for trace amounts of Mn, Fe, Co, Ni, Cu, Zn, Cd, Hg and Pb in water was developed using preconcentration with an iminodiacetate extraction disk (IED). The IED was coated on both faces with commercially available laminate film to prevent x-ray damage to the IED by strong x-irradiation (4 kW; 50 kV, 80 mA) of the wavelength-dispersive x-ray fluorescence spectrometer. Lamination of the IED prolongs its life from 7 to about 200 min at 4 kW ...
Tópico(s): Heavy metals in environment
2006 - Wiley | X-Ray Spectrometry
Kazuhiro Fujita, Hideki Kawaguchi, Igor Zagorodnov, T. Weiland,
We describe and demonstrate a time-domain boundary-element method for numerical computation of wake fields. The accelerator structure is modeled with a surface mesh, and the wake field is easily split from the self fields of the source particles. The formulation for three-dimensional structures is introduced first, followed by two formulations for axisymmetric structures. We briefly describe methods for computing the wake potential in a boundary-element code. Finally, we compare the fully axisymmetric ...
Tópico(s): Electromagnetic Scattering and Analysis
2006 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Nuclear Science
Kazuhiro Fujita, Andrew Schmidt, Eun-Ah Kim, Michael J. Lawler, Dung-Hai Lee, J. C. Davis, Hiroshi Eisaki, Shin‐ichi Uchida,
One of the key motivations for the development of atomically resolved spectroscopic imaging STM (SI-STM) has been to probe the electronic structure of cuprate high temperature superconductors. In both the d-wave superconducting (dSC) and the pseudogap (PG) phases of underdoped cuprates, two distinct classes of electronic states are observed using SI-STM. The first class consists of the dispersive Bogoliubov quasiparticles of a homogeneous d-wave superconductor. These are detected below a lower energy ...
Tópico(s): Inorganic Fluorides and Related Compounds
2012 - Physical Society of Japan | Journal of the Physical Society of Japan
Yu Toyoshima, Hiroaki Kakuda, Kazuhiro Fujita, Shinsuke Uda, Shinya Kuroda,
Sensitivity is one of the hallmarks of biological and pharmacological responses. However, the principle of controlling sensitivity remains unclear. Here we theoretically analyse a simple biochemical reaction and find that the signal transfer efficiency of the transient peak amplitude attenuates depending on the strength of negative regulation. We experimentally find that many signalling pathways in various cell lines, including the Akt and ERK pathways, can be approximated by simple biochemical ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2012 - Nature Portfolio | Nature Communications
Kazuhiro Fujita, Ryosuke Matsui, Takahiro Suzuki, Susumu Kobayashi,
The MIDA touch: A concise and highly convergent protecting-group-free total synthesis of (−)-myxalamide A involves a stereoselective vinylogous Mukaiyama aldol reaction of a vinylketene silyl N,O-acetal, together with a one-pot Stille/Suzuki–Miyaura cross-coupling reaction using Burke's N-methyliminodiacetic acid (MIDA) boronate to connect left- and right-hand fragments of the molecule (see scheme).
Tópico(s): Chemical synthesis and alkaloids
2012 - Wiley | Angewandte Chemie International Edition
Hyoe Takata, Jian Zheng, Keiko Tagami, Tatsuo Aono, Kazuhiro Fujita, Shin-ichi Yamasaki, Noriyoshi Tsuchiya, Shigeo Uchida,
Tópico(s): Groundwater and Isotope Geochemistry
2012 - Springer Science+Business Media | Environmental Monitoring and Assessment
Inna Vishik, Makoto Hashimoto, Ruihua He, Wei-Sheng Lee, F. Schmitt, Dong-Hui Lu, R. G. Moore, Chao Zhang, W. Meevasana, T. Sasagawa, S. Uchida, Kazuhiro Fujita, Shigeyuki Ishida, M. Ishikado, Yoshiyuki Yoshida, Hiroshi Eisaki, Zahid Hussain, Thomas Devereaux, Zhi‐Xun Shen,
A detailed phenomenology of low energy excitations is a crucial starting point for microscopic understanding of complex materials, such as the cuprate high-temperature superconductors. Because of its unique momentum-space discrimination, angle-resolved photoemission spectroscopy (ARPES) is ideally suited for this task in the cuprates, where emergent phases, particularly superconductivity and the pseudogap, have anisotropic gap structure in momentum space. We present a comprehensive doping- and temperature- ...
Tópico(s): Iron-based superconductors research
2012 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Yasuo Yoshida, Kazuyoshi Horiike, Kazuhiro Fujita,
Tópico(s): Optical Systems and Laser Technology
1993 - Institute of Electronics, Information and Communication Engineers | IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences
Satoru Sasagawa, Yuichi Ozaki, Kazuhiro Fujita, Shinya Kuroda,
Tópico(s): Protein Kinase Regulation and GTPase Signaling
2005 - Nature Portfolio | Nature Cell Biology
Koji Kishimoto, Takashi Kitamura, Kazuhiro Fujita, Genshu Tate, Toshiyuki Mitsuya,
Fine-needle aspiration cytology (FNAC) is a well-established technique for diagnosis of malignant lymphoma (ML). Generally, Giemsa but not Pap stain is used in FNAC. However, cytologic features obtained from Pap stain are also valuable. Very few studies on the cytologic characteristics of ML, as determined by Pap stain, are available. It is easier to observe nuclear irregularity and to identify nucleoli in ML cells by Pap stain than by Giemsa stain. Here, we applied Pap stain for cytomorphologic differential ...
Tópico(s): Ovarian cancer diagnosis and treatment
2005 - Wiley | Diagnostic Cytopathology
Keisuke Ishimaru, Hiroyuki Mizuguchi, Chikanori Hashimoto, Takao Ueda, Kazuhiro Fujita, Masaaki OHMI,
In the Shikoku area, it is eager to request an alternative fine aggregate in stead of natural sand, in particular sea sand, by the reason of prohibition of borrowing sea sand in Seto Island Sea. In this study, the fundamental properties of concrete using copper slag (JIS A 5011-3) or second class fly ash (JIS A 6201) as a part of fine aggregate to apply for plain concrete structure is investigated. It is concluded that the concrete of 20 mm in coarse aggregate maximum size, 50% in water-cement ratio ...
Tópico(s): Bauxite Residue and Utilization
2005 - Society of Materials Science | Journal of the Society of Materials Science Japan
Makoto Hashimoto, Elizabeth Nowadnick, Ruihua He, Inna Vishik, Brian Moritz, Yu He, Kiyohisa Tanaka, R. G. Moore, Dong-Hui Lu, Yoshiyuki Yoshida, M. Ishikado, T. Sasagawa, Kazuhiro Fujita, Shigeyuki Ishida, Shin‐ichi Uchida, Hiroshi Eisaki, Zahid Hussain, Thomas Devereaux, Zhi‐Xun Shen,
In the high-temperature (T(c)) cuprate superconductors, a growing body of evidence suggests that the pseudogap phase, existing below the pseudogap temperature T*, is characterized by some broken electronic symmetries distinct from those associated with superconductivity. In particular, recent scattering experiments have suggested that charge ordering competes with superconductivity. However, no direct link of an interplay between the two phases has been identified from the important low-energy excitations. ...
Tópico(s): Magnetic properties of thin films
2014 - Nature Portfolio | Nature Materials
Akio Watanabe, Tsuyoshi Kato, Yusuke Ito, Izumi Yoshida, Teppei Harada, Takashi Mishima, Kazuhiro Fujita, Masatoshi Watai, Kiyotaka Nakagawa, Teruo Miyazawa,
Toddalia asiatica (L.) Lam. (T. asiatica) has been utilized traditionally for medicinal purposes such as the treatment of diabetes. Currently, the extract is considered to be a good source of anti-diabetic agents, but the active compounds have yet to be identified. In this study, we investigated the effects of fractionated T. asiatica extracts on the differentiation of 3T3-L1 preadipocytes and identified aculeatin as a potential active agent. When 3T3-L1 preadipocytes were treated with aculeatin isolated ...
Tópico(s): Bioactive natural compounds
2014 - Elsevier BV | Biochemical and Biophysical Research Communications