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Gráinne Gilmore, Giles Smith, Andrew Robson, Janice Turner, Amanda Andrews, Christina Hardyment, Nicholas Mosley, Mike Fowle, John McNamara, Caroline Mills, Mike Gerrard, Sebastian Faulks, Edward Owen, Anthony Gibson NFU Director of Communications, Stuart Mansfield, Miranda McLachlan, Simon Singh, Anita Bennett, David Brown, Caroline Stacey, Mr P. G. Brooke, David Aaronovitch, Jane MacQuitty, Simon Barnes, Amanda Ursell, Robert Gutfreund-Walmsley, Peter Lansley, Ashling O'Connor Olympics Correspondent, Simon Hills, Robert Lindsay, Mark Frary, Gwyneth Paltrow, Owen Rees, John Mulvey, Jane Knight, Ivo Tennant, Diana James, Alexandra Frean Education Editor, Emma Cook, Maggie Alexander, Philip Howard, D. J. Hutson, Julia Brookes, Carol Midgley, John Wilkins, David Chater, Ben Hoyle Arts Reporter, Michael Binyon, James Bone, Rachel Campbell-Johnston, Lyubov Osinkina, Dominic Wells, Melissa Katsoulis, Clive Davis, Charles G. Blake, Patrick Kidd, Graham Stewart, Lauren Thompson, Amanda Andrews Media Business Correspondent, Miles Costello Finance Correspondent, Wendy Ide, John Bungey, Kevin Eason, Patricia, Lucy Bannerman, Hillary Clinton, Giles Coren, Caroline Hendrie, Sathnam Sanghera, Dr Copperfield, Ben Webster Transport Correspondent, Pat Gibson, Nancy Durrant, Mike Wade, Jane MacArtney, Vinny Lee, James Collis, Nicci French, Siobhan Kennedy, Francis Elliott, Katherine Swift, Deborah Haynes, Jack Malvern, Dominic Walsh, Charlie Flindt, Dan Sabbagh Media Editor, Debra Craine, Rory Watson, Gary Jacob, Matthew Barbour, Victoria Segal, Greg Watts, Norman Harris, J. Cook, Carolyn Lyons, Tim Reid, Daniel Finkelstein, Allan Simmons, Ruth Gledhill Religion Correspondent, Laura Lovett, David Croghan, Phoebe Greenwood, Jo Morris, Gethin Jones, Nick Wyke, Sophie Harris, Rhys Blakely, Derek Thom, Valerie Elliott Consumer Editor, Richard Lloyd Parry, Andrew Ellson Personal Finance Editor, David Hands, WPW, Norman Parry, Laura Miller, Jamie Walker, Adam Sherwin Media Correspondent, Ben MacHell, Karl A. Ziegler, Lucy Sweeney, David Charter, Stuart Machin, Edward Gorman, Derwent May, Pat Murphy Chairman, Jeremy Plester, Tim Teeman, Theo Wells, Aggie MacKenzie, Lesley Diss, Russell Kempson, Ed Potton, Julia Roberts, Gary Duncan Economics Editor, Ayo Odelusi, Oliver Kay, Stephen Anderton, David Lister, Mark Atherton, Lisa Armstrong, Mat Smith, John Westerby, Michael Theodoulou, Sarah Vine, Peter Ellegard, Tom Baldwin, Jane Wheatley, Sam Coates, Lord Ravensdale, Sally Baker, Pete Paphides, David Baddiel, Rose Heiney, Rob Wright, Geoffrey Dean, Robert Knight, Christina Koning, Edward Gorman Motor Racing Correspondent, Neil Harman Tennis Correspondent, Raymond Keene, J. D. Holiday, Suzi Godson, Kate Saunders, Lewis Smith, Matthew Pryor, Matt Hughes, Gordon Ramsay, Rob Hastings Cricket Master, Sean O'Neill, Jean Donaldson, Roger Phillips, Rick Jones, Neville Scott, Chris Campling, David Gibbs Education Officer, Vernon Scarborough, Christopher Martin-Jenkins Chief Cricket Correspondent, Rebecca O'connor, Ross Leckie, Erica Wagner, Roger Boyes, Marcel Berlins, Francis Elliott Deputy Political Editor, Philip Mathews, James Charles, Nick Hasell, Thomasina Miers, Margaret Reynolds, Nell Fisher, David Hands Rugby Correspondent, Kevin Maher, Paul Simmonds, Nicholas Clee, Steve Jelbert, Nigel Kendall, Joanna Pitman, Dominic Kennedy, Giles Whittell, Richard Frost, Richard Ehrlich, Robert Crampton, Steve Hawkes, Jane Shilling, Tim Hames, Harriet Addison, Barbara Aldridge, Dominic Maxwell, James Anderson, Kevin Keegan, Matthew Parris, Mark Bridge, Richard Owen Rome Correspondent, Thomas Catan, Angus MacLeod, Mike Smith, George Caulkin, Amanda Craig, Russell Jenkins, Neil Fisher, Sheila Keating, Celia Dodd, Caitlin Moran, Iain Finlayson, David Lunan, Ben MacIntyre, John Flanders, Tony Dawe, Joe Clay, David Hutcheon, Rajeev Syal, Philip Webster, John Naish, Philip Pangalos, Bojan Pancevski, Ben MacIntyre, former new York correspondent, Martin Waller, Karen Johnston, James Jackson, Patrick Foster, Wayne Nation, Anna Shepard, Louise Cohen, Benedict Nightingale, Roger Dobson, Dr Thomas Stuttaford, Stephen Dalton, Leo Lewis, Russell Celyn Jones, Global Hippy, Richard Morrison, Robert Mighall, James Christopher, Robert Cole Personal Investor, Alice Miles, David Budworth, Valerie Grove, Simon Crompton, Archie Goodwin, Michael Evans, Alan Lee Racing Correspondent, Lisa Tuttle, Alan Jackson, Matt Roberts, wendy Ide, Roy Foster, Miles Costello, Timothy L. Tatham, R, Gloucestershire, William Palin, Steve Keenan Online Travel Editor, Mark Bristow, Christopher Irvine,

... dignity, says Kevin Maher Death Note Director: Shusuke Kaneko, 12A, 126 min Stars: Tatsuya Fujiwara, Ken'ichi Matsuyama, Asaka Seto, Erika Toda On selected ...

2008 - Gale Group | TDA

Artigo Revisado por pares

Tatsuo Kaneko, Ken Imamura, Junji Watanabe,

... Main-Chain Type of Liquid Crystalline PolyimideTatsuo I. Kaneko, Ken Imamura, and Junji WatanabeView Author Information Department of ...

Tópico(s): Epoxy Resin Curing Processes

1997 - American Chemical Society | Macromolecules

Artigo Revisado por pares

Kenichi Kaneko, Nobuo Hashimoto,

... O9 and Yersinia pseudotuberculosis in Mice Ken-ichi Kaneko, Ken-ichi Kaneko Department of Veterinary Public Health, Faculty ... for more papers by this author Ken-ichi Kaneko, Ken-ichi Kaneko Department of Veterinary Public Health, Faculty of Veterinary ...

Tópico(s): Ginseng Biological Effects and Applications

1983 - Wiley | Microbiology and Immunology

Carta Revisado por pares

Shunzo Chiba, Kenichi Kaneko, Nobuo Hashimoto, Tooru Nakao,

Chiba, Shunzo M.D.; Kaneko, Ken-ichi D.V.M.; Hashimoto, Nobuo D.V.M.; Nakao, Tooru M.D. Author Information

Tópico(s): Streptococcal Infections and Treatments

1983 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal

Revisão Acesso aberto Revisado por pares

Ken Asada, Syuzo Kaneko, Ken Takasawa, Hidenori Machino, Satoshi Takahashi, Norio Shinkai, Ryo Shimoyama, Masaaki Komatsu, Ryuji Hamamoto,

With the completion of the International Human Genome Project, we have entered what is known as the post-genome era, and efforts to apply genomic information to medicine have become more active. In particular, with the announcement of the Precision Medicine Initiative by U.S. President Barack Obama in his State of the Union address at the beginning of 2015, "precision medicine," which aims to divide patients and potential patients into subgroups with respect to disease susceptibility, has become ...

Tópico(s): RNA modifications and cancer

2021 - Frontiers Media | Frontiers in Oncology

Artigo Acesso aberto Revisado por pares

T. Kaneko, Ken’ya Furuta, Kazuhiro Oiwa, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa,

Nanopatterning of motors reveals that the number and spacing of kinesin-14, and not of kinesin-1, dictate microtubule velocity.

Tópico(s): Cellular Mechanics and Interactions

2020 - American Association for the Advancement of Science | Science Advances

Artigo Acesso aberto Revisado por pares

Kentaro Hara, Tamotsu Kuroki, Shohei Kaneko, Ken Taniguchi, Masashi Fukuda, Toru Onita, Terumitsu Sawai,

Compartment syndrome that occurs after lengthy surgery in the lithotomy position is known as well-leg compartment syndrome. It has serious consequences for patients, including amyotrophic renal failure, limb loss, and sometimes even death. This study aimed to identify effective preventive measures against well-leg compartment syndrome using a retrospective cohort study of 1,951 patients (985 and 966 in the prevention and control groups, respectively).The following preventive interventions were analyzed: ( ...

Tópico(s): Electroconvulsive Therapy Studies

2020 - Elsevier BV | Surgery Open Science

Artigo Acesso aberto Revisado por pares

Hitomi Ogata, Masaki Horie, Momoko Kayaba, Yoshiaki Tanaka, Akira Ando, Insung Park, Simeng Zhang, Katsuhiko Yajima, Junichi Shoda, Naomi Omi, Miki Kaneko, Ken Kiyono, Makoto Satoh, Kumpei Tokuyama,

Breakfast is often described as “the most important meal of the day” and human studies have revealed that post-prandial responses are dependent on meal timing, but little is known of the effects of meal timing per se on human circadian rhythms. We evaluated the effects of skipping breakfast for 6 days on core body temperature, dim light melatonin onset, heart rate variability, and clock gene expression in 10 healthy young men, with a repeated-measures design. Subjects were provided an isocaloric ...

Tópico(s): Sleep and related disorders

2020 - Multidisciplinary Digital Publishing Institute | Nutrients

Artigo Revisado por pares

Satoshi Kawamura, Daisuke Tanaka, Taisuke Tanaka, Daisuke Noguchi, Yuichiro Hayakawa, Minami Kaneko, Ken Saito, Fumio Uchikoba,

Tópico(s): Prosthetics and Rehabilitation Robotics

2018 - Springer Science+Business Media | Artificial Life and Robotics

Artigo Revisado por pares

Samar Helou, Elie El Helou, Naoko Evans, Taiki Shigematsu, Jeanine El Helou, Miki Kaneko, Ken Kiyono,

Eye contact is generally considered a beneficial non-verbal behavior in patient-physician communication. Physicians are advised to simulate eye contact during video consultations by gazing at the camera, although we lack evidence that doing so is beneficial. This work is a cross-cultural experiment that aims to answer: “Are physicians who gaze at the camera during video consultations perceived as making eye contact, and are their communication skills rated higher?” 43 Japanese and 61 Lebanese participants ...

Tópico(s): Social Media in Health Education

2022 - Elsevier BV | International Journal of Medical Informatics

Artigo Acesso aberto Revisado por pares

Junichi Miyazaki, Akiko Makabe, Yohei Matsui, Naoya Ebina, Saki Tsutsumi, Jun-ichiro Ishibashi, Chong Chen, Sho Kaneko, Ken Takai, Shinsuke Kawagucci,

Deep-sea geofluid systems, such as hydrothermal vents and cold seeps, are key to understanding subseafloor environments of Earth. Fluid chemistry, especially, provides crucial information towards elucidating the physical, chemical and biological processes that occur in these ecosystems. To accurately assess fluid and gas properties of deep-sea geofluids, well-designed pressure-tight fluid samplers are indispensable and as such they are important assets of deep-sea geofluid research. Here, the development ...

Tópico(s): Hydrocarbon exploration and reservoir analysis

2017 - Frontiers Media | Frontiers in Earth Science

Artigo Acesso aberto Revisado por pares

Yohei Yamaguchi, Gentaro Iribe, Toshiyuki Kaneko, Ken Takahashi, Takuro Numaga‐Tomita, Motohiro Nishida, Lutz Birnbaumer, Keiji Naruse,

When a cardiac muscle is held in a stretched position, its [Ca2+] transient increases slowly over several minutes in a process known as stress-induced slow increase in intracellular Ca2+ concentration ([Ca2+]i) (SSC). Transient receptor potential canonical (TRPC) 3 forms a non-selective cation channel regulated by the angiotensin II type 1 receptor (AT1R). In this study, we investigated the role of TRPC3 in the SSC. Isolated mouse ventricular myocytes were electrically stimulated and subjected to sustained ...

Tópico(s): Insect and Pesticide Research

2017 - BioMed Central | The Journal of Physiological Sciences

Artigo Acesso aberto Revisado por pares

Toshimitsu Honma, Hirotomo Ohba, Ayako Kaneko, Ken Nakamura, Tomoyuki Makino, Hidetaka Katou,

Concentrations of arsenic (As) and cadmium (Cd) in rice grains are of public concern for human health. We conducted field experiments to investigate the effects of soil amendment applications, combined with different water management practices, on As and Cd uptake by rice plants (Oryza sativa L. cv. Koshihikari). Prolonged flooding, practiced for pre-heading 3 weeks and post-heading 3 weeks, led to elevated As concentrations in the soil solution and rice grain. Rainfed water management, in which no ...

Tópico(s): Heavy Metal Exposure and Toxicity

2016 - Taylor & Francis | Soil Science & Plant Nutrition

Revisão Acesso aberto Revisado por pares

Hiroko Segawa, Yuji Shiozaki, Ichiro Kaneko, Ken–ichi Miyamoto,

Inorganic phosphate (Pi) is an essential compound for several biologic functions. Pi levels outside the normal range, however, contribute to several pathological processes. Hypophosphatemia leads to bone abnormalities, such as rickets/osteomalacia. Hyperphosphatemia contributes to vascular calcification in patients with chronic kidney disease and hemodialysis patients and is independently associated with cardiac mortality.Pi homeostasis is regulated by the coordinated function of renal and intestinal ...

Tópico(s): Magnesium in Health and Disease

2015 - Center for Academic Publications Japan | Journal of Nutritional Science and Vitaminology

Artigo Acesso aberto Revisado por pares

Shin-ichi Kaneko, Ken Matsuba, Muhammad Hafiz, Keigo Yamasaki, Erika Kakizaki, Nobuhiko Nishida, Hiroyuki Takeya, K. Hirata, Takuto Kawakami, Takeshi Mizushima, Kazushige Machida,

Quantized bound states at a vortex core are discretized in YNi 2 B 2 C. By using scanning tunneling spectroscopy with an unprecedented 0.1 nm spatial resolution, we find and identify the localized spectral structure, where in addition to the first main peak with a positive low energy, a second subpeak coming from the fourfold symmetric gap structure is seen inside the energy gap. Those spectral features are understood solving the Bogoliubov–de Gennes equation for a fully three-dimensional gap structure. ...

Tópico(s): Rare-earth and actinide compounds

2012 - Physical Society of Japan | Journal of the Physical Society of Japan

Artigo Acesso aberto Revisado por pares

Keita Kuroiwa, Masaki Yoshida, Shigeyuki Masaoka, Kenji Kaneko, Ken Sakai, Nobuo Kimizuka,

Mix and shake: Lipid packaged dinuclear ruthenium(II,III) complexes of class III mixed-valence state produce a reversible hypochromic effect upon external physical stimuli, such as shaking, due to the arrangement of transition dipole moments. The effect is accompanied by tubular-to-ribbon structural changes (see scheme). Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available ...

Tópico(s): Supramolecular Chemistry and Complexes

2011 - Wiley | Angewandte Chemie International Edition

Artigo Revisado por pares

Tsuyoshi Saito, Hiroyuki Mitomi, Hiroshi Izumi, Yoshiyuki Suehara, Taketo Okubo, Tomoaki Torigoe, Tatsuya Takagi, Kazuo Kaneko, Ken Sato, Toshiharu Matsumoto, Takashi Yao,

A 46-year-old man was admitted to the hospital with a recurrent giant-cell tumor of the distal femur. This was his fourth recurrence, and it had occurred 16 years after his last treatment. The resected recurrent tumor was histologically determined to be a conventional giant-cell tumor. However, a single lung metastatic lesion and local recurrence were noticed 6 months after the resection, both of which were surgically excised. The lung lesion was histologically determined to be an implantation of ...

Tópico(s): Sarcoma Diagnosis and Treatment

2011 - Elsevier BV | Human Pathology

Artigo Revisado por pares

Kazunari Kaneko, Ken Yoshimura, Atsushi Ohashi, Takahisa Kimata, Tomohiko Shimo, Shoji Tsuji,

Tópico(s): Cardiac Structural Anomalies and Repair

2011 - Springer Science+Business Media | Pediatric Cardiology

Artigo Acesso aberto Revisado por pares

Mariko Noguchi, Tomoko Suzuki, Kazuya Kabayama, Hiroki Takahashi, Hirofumi Chiba, Masanori Shiratori, Shosaku Abe, Atsushi Watanabe, Masaaki Satoh, Tadashi Hasegawa, Seiichi Tagami, Atsushi Ishii, Masaki Saitoh, Masanori Kaneko, Ken Iseki, Yasuyuki Igarashi, Jin‐ichi Inokuchi,

Expression of gangliosides and alterations in their composition have been observed during cell proliferation and differentiation and in certain cell cycle phases, brain development and cancer malignancy. To investigate the characteristics of GM3 synthase, SAT‐I mRNA and ganglioside GM3 expression levels in lung cancer, we examined the expression levels of SAT‐I mRNA as well as GM3 in 40 tumor tissues surgically removed from non‐small cell lung cancer patients. Adenocarcinoma tissues expressed SAT‐ ...

Tópico(s): Caveolin-1 and cellular processes

2007 - Wiley | Cancer Science

Artigo Revisado por pares

Hitoshi Takeda, Takahide Kaneko, Ken Harada, Yasushi Matsuzaki, Hajime Nakano, Katsumi Hanada,

Photodynamic therapy (PDT) using topical delta-aminolevulinic acid (ALA) has been used for nonmelanoma skin cancers, including malignant cutaneous T-cell lymphomas. Moreover, PDT has been tried for benign inflammatory or infectious skin lesions.To evaluate the effects of ALA-PDT on skin lesions of lymphadenosis benigna cutis (LABC).Two 16-year-old females with solitary and infiltrated nodules were treated 5 times with topical ALA-PDT.Both patients responded well and showed dramatic clinical and histopathological ...

Tópico(s): Photodynamic Therapy Research Studies

2005 - Karger Publishers | Dermatology

Artigo Revisado por pares

Kiyoshi Ando, Atsushi Kaneko, Ken‐ichi Kawarabayashi,

Tópico(s): Advanced Graph Theory Research

2005 - Springer Science+Business Media | Graphs and Combinatorics

Artigo Revisado por pares

Shohei Yokoyama, Hajime Nakano, Aya Nishizawa, Takahide Kaneko, Ken Harada, Katsumi Hanada,

Photodynamic therapy (PDT) with topical application of 5-aminolaevulinic acid (ALA) is a promising new treatment option for the management of various cutaneous malignancies. Generally, topical ALA-based PDT has relatively insignificant adverse effects of transient character; these include itching, stinging or burning pain and slight to moderate erythema. We describe the first case of photocontact urticaria induced by topical ALA-based PDT for the treatment of unilesional mycosis fungoides. Although ...

Tópico(s): Nail Diseases and Treatments

2005 - Wiley | The Journal of Dermatology

Artigo Revisado por pares

Kazuyuki Kaneko, Ken’ichi Yokoyama, Keiji Moriyama, Kenzo Asaoka, Jun-ichi Sakai, Michihiko Nagumo,

Tópico(s): Corrosion Behavior and Inhibition

2003 - Elsevier BV | Biomaterials

Artigo Revisado por pares

Kiyoshi Ando, Yoshimi Egawa, Atsushi Kaneko, Ken‐ichi Kawarabayashi, Haruhide Matsuda,

A graph G is called claw-free if G has no induced subgraph isomorphic to K1,3. We prove that if G is a claw-free graph with minimum degree at least d, then G has a path factor such that the order of each path is at least d+1.

Tópico(s): Graph theory and applications

2002 - Elsevier BV | Discrete Mathematics

Artigo Acesso aberto Revisado por pares

Yuji Honda, Shinji Tanimori, Mitsunori Kirihata, Satoshi Kaneko, Ken Tokuyasu, Masayuki Hashimoto, Takeshi Watanabe, Tamo Fukamizo,

The kinetic behavior of chitinase A1 from Bacillus circulans WL-12 was investigated using the novel fluorogenic substrates, N-deacetylated 4-methylumbelliferyl chitobiosides [GlcN-GlcNAc-UMB (2), GlcNAc-GlcN-UMB (3), and (GlcN)(2)-UMB (4)], and the results were compared with those obtained using 4-methylumbelliferyl N, N'-diacetylchitobiose [(GlcNAc)(2)-UMB (1)] as the substrate. The chitinase did not release the UMB moiety from compound 4, but successfully released UMB from the other substrates. k(cat)/ ...

Tópico(s): Legume Nitrogen Fixing Symbiosis

2000 - Wiley | FEBS Letters

Artigo Acesso aberto Revisado por pares

Kaoru Kaneko, Ken Kanada, Masaharu Miyagi, Noriyasu Saito, Tetsuya Ozeki, Hiroshi Yuasa, Yoshio Kanaya,

Sodium alginate (ALNa) of a natural polysaccharide is known to form a water-insoluble gel when combined with a bivalent metal. In this study, we prepared tablets containing ALNa and calcium gluconate (GLCa) as a bivalent metal, and studied the application of the water-insoluble gel involving the controlled release of a test drug by permeation of water. Dry-coated tablets containing theophylline (TP) as a model drug, ALNa and GLCa were prepared by the dry power compression method. The controlled release ...

Tópico(s): Hydrogels: synthesis, properties, applications

1998 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin

Artigo Revisado por pares

Kyosuke Kaji, Koichi Tsuneyama, Yasuni Nakanuma, Kenichi Harada, Motoko Sasaki, Shuichi Kaneko, KEN‐ICHI KOBAYASHI,

ABSTRACT Bile duct damage in patients with chronic hepatitis C (hepatitis‐associated bile duct lesion) as well as that in patients with primary biliary cirrhosis (PBC; chronic non‐suppurative destructive cholangitis), may be causally related to immunological assaults. Efficient antigen presentation is known to require the provision of a costimulatory signal which is dependent on the CD28 on T cell surfaces, and that at least two molecules, B7‐1 and B7‐2, work as costimulatory ligands for CD28. In ...

Tópico(s): Drug Transport and Resistance Mechanisms

1997 - Wiley | Journal of Gastroenterology and Hepatology

Artigo Acesso aberto Revisado por pares

Kaoru Kaneko, Ken Kanada, Tatsuhiko Yamada, Masaharu Miyagi, Noriyasu Saito, Tetsuya Ozeki, Hiroshi Yuasa, Yoshio Kanaya,

Masking of the bitter taste from tablets by a water-insoluble gel formed by sodium alginate and bivalent metal was studied. Amiprilose hydrochloride was selected as the model drug with a bitter taste, and its core tablet was prepared. The core tablet was under-coated with sodium alginate and over-coated with calcium gluconate as a bivalent metal, or it was under-coated with calcium gluconate and over-coated with sodium alginate in order to form a gel on the surface of the tablet in the mouth at ...

Tópico(s): Surfactants and Colloidal Systems

1997 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin

Artigo Acesso aberto Revisado por pares

Takami Tomiyama, Hideshi Kaneko, Ken-ichiro Kataoka, Satoshi Asano, Noriaki Endo,

Rifampicin and its analogues,p-benzoquinone and hydroquinone, inhibited the toxicity of preformed aggregates of human islet amyloid polypeptide, amylin, to rat pheochromocytoma PC12 cells, when preincubated with the aggregated peptide before addition to cell cultures. Immunofluorescence microscopy showed that they prevented the adhesion of amylin aggregates to the cell surface, and this effect was induced probably by their binding to peptide fibrils during preincubation. Other quinone derivatives, ...

Tópico(s): Computational Drug Discovery Methods

1997 - Portland Press | Biochemical Journal

Artigo

Tetsuro Oikawa, Jiro Hitomi, Akira Kono, Eizō Kaneko, Ken Yamaguchi,

Limited information is available concerning the involvement of growth factor receptors and their ligands in the pathogenesis of human pancreatic cancer. We analyzed 12 human pancreatic cancer cell lines by Northern blot analysis for the expression of 9 receptor tyrosine kinases (RTKs) and 6 growth factors. The effect of a monoclonal antibody (MAb) against transforming growth factor-α (TGF-α) on in vitro pancreatic cancer cell growth was also assessed. mRNA for EGF-R, c-erbB-2 and c-erbB-3 was expressed ...

Tópico(s): Pancreatic and Hepatic Oncology Research

1995 - Humana Press | International Journal of Pancreatology