Tomonari Murakami, Teppei Matsui, Masato Uemura, Kenichi Ohki,
Tópico(s): Visual perception and processing mechanisms
2022 - Nature Portfolio | Nature
Misako Nagatsuma, Kei Takasawa, T Yamauchi, Ryuichi Nakagawa, Tomoko Mizuno, Eriko Tanaka, Kouhei Yamamoto, Noriko Uemura, Kenichi Kashimada, Tomohiro Morio,
Tópico(s): Mast cells and histamine
2018 - Springer Nature | Journal of Human Genetics
T. Fukami, Hiroyuki Ishii, Nobuhiko Kobayashi, Takafumi Uemura, Kenichi Sakai, Yugo Okada, Jun Takeya, Kei Hirose,
We find that the phase coherence factor derived from Hall effect measurements of single-crystal thin-film field-effect transistors of pentacene, which relates the intrinsic charge transport with the phase coherence, has a strong correlation with the thermal fluctuations of transfer energies between neighboring molecules. This observation also holds true for other organic semiconductors such as tetracene, dianthrathiophene (DAT)-V, and dinaphtho[2,3-b:2′,3′-f]thieno[3,2-b]thiophene (DNTT). This gives ...
Tópico(s): Organic Electronics and Photovoltaics
2015 - American Institute of Physics | Applied Physics Letters
Shiro Uemura, Kenichi Ishigami, Tsunenari Soeda, Satoshi Okayama, Ji Hee Sung, Hitoshi Nakagawa, Satoshi Somekawa, Yukiji Takeda, Hiroyuki Kawata, Manabu Horii, Yoshihiko Saito,
Morphological characteristics of non-significant coronary plaques (NSCPs) that develop rapid progression have not been fully elucidated. The aim of this study was to clarify the morphological characteristics of NSCPs in patients with coronary artery disease (CAD) using intravascular optical coherence tomography (OCT). Fifty-three consecutive CAD patients undergoing percutaneous coronary intervention were enrolled and 69 NSCPs (per cent diameter stenosis <50%) were identified on baseline angiogram. Baseline ...
Tópico(s): Cardiac Imaging and Diagnostics
2011 - Oxford University Press | European Heart Journal
Tetsuro Yamamoto, Takahiko Horiuchi, Yojiro Arinobu, Yasushi Inoue, Hiroaki Niiro, Yoichiro Kashiwagai, Shin‐ichi Harashima, Hiroshi Tsukamoto, Koichi Akashi, Hisaaki Miyahara, Shigeru Yoshizawa, Junichi Maehara, Eisuke Shono, Kazuto Takamura, Haruhisa Machida, Kaoru Tsujioka, Takehiko Kaneko, N. Uemura, Kenichi Suzawa, Norihiko Inagaki, Noriko Umegaki, Yoshihiro Kasamatsu, Akihito Hara, Tomoko Tahira,
Tópico(s): Autoimmune Bullous Skin Diseases
2011 - Elsevier BV | The American Journal of the Medical Sciences
Takashi Nomura, Yuichi Inoue, Birgit Högl, Yusuke Uemura, Kenichi Yasui, Taeko Sasai, Kazuyoshi Namba, Kenji Nakashima,
Aims: The aim of this study was to evaluate differences in the clinical presentation and polysomnographic characteristics of rapid eye movement sleep behavior disorder (RBD) between patients with Parkinson's disease (PD) and those with multiple system atrophy (MSA). Methods: We conducted clinical interviews examining RBD symptoms, including violent and non‐violent behaviors, in 49 patients with PD and 16 patients with MSA (as well as their bed partners) and performed polysomnography on all subject patients. ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2011 - Wiley | Psychiatry and Clinical Neurosciences
Koichi Kaikita, Masakazu Matsukawa, Kenji Soejima, Shunichiro Fuchigami, Yuji Miyazaki, Takamichi Ono, Takashi Uemura, Kenichi Tsujita, Seiji Hokimoto, Hitoshi Sumida, Kunihiko Matsui, Hiroshige Yamabe, Hisao Ogawa, Mitsutoshi Miura,
Summary High plasma level of von Willebrand factor (VWF) is a marker of future cardiovascular events in patients at high risk of coronary artery disease (CAD). The purpose of this study was to examine the changes and the prognostic value of plasma VWF-cleaving protease (ADAMTS13) levels in patients with CAD. Plasma VWF and ADAMTS13 levels were measured in 225 patients with CAD (152 men and 73 women, age, 70.3 ± 8.9 years, mean ± SD) and 100 patients without CAD who were ageand gender-matched to the CAD ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2010 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Mihoko Kondo-Nakamura, Kaori Shintani‐Ishida, Koichi Uemura, Kenichi Yoshida,
Tópico(s): Neonatal Health and Biochemistry
2010 - Elsevier BV | Biochemical and Biophysical Research Communications
Yoshinobu MORIKAWA, Shiro Uemura, Kenichi Ishigami, Tsunenari Soeda, Satoshi Okayama, Y. Takemoto, Kenji Onoue, Satoshi Somekawa, Taku Nishida, Yukiji Takeda, Hiroyuki Kawata, Manabu Horii, Yoshihiko Saito,
Background Coronary spasm (CS) plays an important role in the pathogenesis of many types of ischemic heart disease, but morphological appearance of non-stenotic coronary segments with CS is not fully understood. We evaluate the morphological characteristics of coronary arteries in patients with coronary spastic angina (CSA) using intravascular optical coherence tomography (OCT). Methods We evaluated 37 patients with resting chest pain whose coronary angiograms did not reveal significant stenosis. These ...
Tópico(s): Optical Coherence Tomography Applications
2009 - Elsevier BV | International Journal of Cardiology
Hiroshi Ikegaya, Makoto Nakajima, Kaori Shintani‐Ishida, Koichi Uemura, Kenichi Yoshida,
Abstract Objective: A 30‐year‐old woman with a 2‐year history of bulimia nervosa and severe abdominal pain after excessive food consumption visited our emergency room. Her abdomen showed marked generalized distension. Method: Aspiration of the gastric contents was not successful, and despite efforts to resuscitate her, the patient died. Result: An autopsy showed a markedly distended stomach containing approximately 6,500 ml of solid foods. The aortomesenteric distance was <1.0 cm and the aortomesenteric ...
Tópico(s): Intestinal Malrotation and Obstruction Disorders
2006 - Wiley | International Journal of Eating Disorders
Kaori Shintani‐Ishida, Makoto Nakajima, Koichi Uemura, Kenichi Yoshida,
Ischemic preconditioning (IP) conferred by brief ischemia–reperfusion induces resistance to cell injury due to the following lethal ischemia. This study aimed to elucidate whether 78-kDa glucose-regulated protein (GRP78), a main ER molecular chaperone, contributes to IP-mediated protection against ischemic myocardial injury. In a rat coronary artery occlusion model, the GRP78 protein level increased to 210% of the sham level by early IP with three cycles of 4-min ischemia and 4-min reperfusion. The ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2006 - Elsevier BV | Biochemical and Biophysical Research Communications
Hajime Nishio, Shinji Takai, Mizuo Miyazaki, Hidekazu Horiuchi, Motoki Osawa, Koichi Uemura, Kenichi Yoshida, Masahiro Mukaida, Yasuhiro Ueno, Koichi Suzuki,
Tópico(s): Asthma and respiratory diseases
2005 - Springer Science+Business Media | International Journal of Legal Medicine
Kyoko Maruyama, Kazumoto Iijima, Masahiro Ikeda, Akiko Kitamura, Hiroyasu Tsukaguchi, Kunihiko Yoshiya, Sakurako Hoshii, Naohiro Wada, Osamu Uemura, Kenichi Satomura, Masataka Honda, Norishige Yoshikawa,
Tópico(s): Chronic Kidney Disease and Diabetes
2003 - Springer Science+Business Media | Pediatric Nephrology
Nobuo Morita, Hirotsugu Uemura, Kenichi Tsumatani, M Cho, Yoshihiko Hirao, Eijiro Okajima, N Konishi, Y Hiasa,
The E-cadherin–catenin complex plays an important role in establishing and maintaining intercellular connections and morphogenesis and reduced expression of its constituent molecules is associated with invasion and metastasis. In the present study, we examined E-cadherin and α-, β- and γ-catenin levels in tumour tissues obtained by radical prostatectomy in order to investigate the relationship with histopathological tumour invasion. Immunohistochemical findings for 45 prostate cancer specimens demonstrated ...
Tópico(s): Kruppel-like factors research
1999 - Springer Nature | British Journal of Cancer
Sumihisa Hoshino, Yousuke Kikuchi, Makoto Nakajima, Hiroko Kimura, Shingo Tsuyama, Koichi Uemura, Kenichi Yoshida,
The link between endothelial nitric oxide synthase (eNOS) activation and vascular diameter during ischemia-reperfusion was investigated in the rat heart. After short ( 45 min) time of ischemia conferred by coronary artery occlusion of the rats, reperfusion caused dilatation and constriction of arterioles, respectively. Partial oxygen pressure (pO2) measurement of the heart by the electrode confirmed the hyper-perfusion and no-reflow phenomena during reperfusion, as well as myocardial ischemia. The vascular ...
Tópico(s): Electron Spin Resonance Studies
2005 - Taylor & Francis | Free Radical Research
Takuya Uemura, Kenichi Kazuki, Mitsuhiro Okada, Takeshi Egi, Kunio Takaoka,
Macrodactyly is a relatively rare congenital abnormality of the fingers and toes and is difficult to treat. We report a new method for treating toe macrodactyly in which a nail with a vascularised pedicle is raised, the toe is shortened to an appropriate length, and the nail transferred to an aesthetically appropriate proximal site. Although this technique is of a higher level of difficulty than conventional procedures involving pedicled nail flaps, allows aesthetically more favourable nail reconstruction ...
Tópico(s): Vascular Malformations and Hemangiomas
2005 - Elsevier BV | British Journal of Plastic Surgery
Tetsuro Shimo, Shinichi Yamasaki, Kenichi Date, Hisako Uemura, Kenichi Somekawa,
Abstract Photosensitized cycloaddition of 4,6‐dimethyl‐2‐pyrone ( 1 ) with methacrylonitrile ( 3b ) afforded two types of [2 + 2]cycloadducts, 4b and 6b , across the C 5 ‐C 6 and C 3 ‐C 4 double bonds in 1 , respectively. Photosensitized reactions of 1 with dimethyl maleate and dimethyl cyclobutene‐1,2‐dicarboxylate gave [2 + 2]cycload‐ducts 4d, 4e across the C 5 ‐C 6 double bond, in addition to [4 + 2]cycloadduct 9d or bicyclo[4.2.0]octadiene 10e . The photoreactions of methyl 2‐pyrone‐5‐carboxylate ( 2 ) with 3b and 2‐chloroacrylonitrile ( ...
Tópico(s): Oxidative Organic Chemistry Reactions
1993 - Wiley | Journal of Heterocyclic Chemistry
Masaaki Waragai, Saori Hata, Toshiharu Suzuki, Ryotaro Ishii, Chihiro Fujii, Takahiko Tokuda, Hiroyuki Arai, Takashi Ohrui, Susumu Higuchi, Madoka Yoshida, Kazuei Igarashi, Masaru Moriya, Naomichi Iwai, Kenichi Uemura,
We validated the utility of SPM8 plus DARTEL (VSRAD) combined with magnetic resonance spectroscopy (1 H MRS) as an adjunct screening technique for dementia due to Alzheimer's disease (AD). We examined the posterior cingulate gyri of 228 subjects usin
Tópico(s): Advanced Neuroimaging Techniques and Applications
2014 - IOS Press | Journal of Alzheimer s Disease
Madoka Yoshida, Kyohei Higashi, Kyoshiro Kuni, Mutsumi Mizoi, Ryotaro Saiki, Mizuho Nakamura, Masaaki Waragai, Kenichi Uemura, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi,
We previously reported that the level of urinary 3-hydroxypropyl mercapturic acid (3-HPMA)/creatinine (Cre) was reduced following stroke. The aim of this study was to determine whether the level of 3-HPMA/Cre in urine was reduced in subjects with dementia. The level of 3-HPMA was measured by LC–MS/MS, and that of amino acid conjugated acrolein (AC-Acro) was by ELISA. The study included 128 elderly subjects divided into 74 non-demented (control), 22 mild cognitive impairment (MCI) and 32 Alzheimer's disease ( ...
Tópico(s): Muscle metabolism and nutrition
2014 - Elsevier BV | Clinica Chimica Acta
Mutsumi Mizoi, Madoka Yoshida, Ryotaro Saiki, Masaaki Waragai, Kenichi Uemura, Hiroyasu Akatsu, Keiko Kashiwagi, Kazuei Igarashi,
We found previously that the amyloid β40/42 (Aβ40/42) ratio and the level of protein-conjugated acrolein (PC-Acro) in plasma were increased in mild cognitive impairment (MCI) and Alzheimer's disease (AD) subjects. We determined whether MCI and AD subjects can be differentiated based on the levels of Aβ40, Aβ42, and PC-Acro in cerebrospinal fluid (CSF). Aβ40, Aβ42, PC-Acro, Tau and phosphorylated Tau in CSF were measured by ELISA. Median values of Aβ40, Aβ40/PC-Acro and Aβ40/42 in CSF were significantly ...
Tópico(s): Folate and B Vitamins Research
2014 - Elsevier BV | Clinica Chimica Acta
Masao Kimura, Y. Niwa, Kenichi Uemura, Tatsuzo Nagai, Yasuhiro Inada, Masaharu Nomura,
We have succeeded in in situ and simultaneously observing the redox reaction of palladium and the oxygen storage/release process in a newly developed palladium-promoted Sr–Fe–O (Pd/Sr–Fe–O) catalyst during redox-gas cycles using dispersive X-ray absorption fine structure (XAFS) analysis at 673 K with a time resolution of less than 20 ms. The Pd/Sr–Fe–O catalyst, which exhibits high performance for automotive emission control, has a unique "multi-phase-domain" structure, where a single grain is composed ...
Tópico(s): Electrocatalysts for Energy Conversion
2013 - | MATERIALS TRANSACTIONS
Masaaki Waragai, Madoka Yoshida, Mutsumi Mizoi, Ryotaro Saiki, Keiko Kashiwagi, Kiyoshi Takagi, Hiroyuki Arai, Jun Tashiro, Makoto Hashimoto, Naomichi Iwai, Kenichi Uemura, Kazuei Igarashi,
The objective of this study was to determine whether plasma levels of acrolein, a compound that causes cell damage, and amyloid-β (Aβ) are useful biochemical markers for Alzheimer's disease (AD). The study included 221 elderly subjects divided into 101 non-demented [33 healthy control and 68 non-demented subjects with white matter hyperintensity (nd-WMH)], 50 mild cognitive impairment (MCI), and 70 AD. Increases in both protein-conjugated acrolein (PC-Acro) and Aβ40/42 ratio were observed in MCI and AD ...
Tópico(s): Ginkgo biloba and Cashew Applications
2012 - IOS Press | Journal of Alzheimer s Disease
Yoshihiro Mori, Kenichi Uemura, Yoshinori Iizuka,
Total-reflection X-ray fluorescence (TXRF) spectrometry with no chemical preconcentration, often called "straight-TXRF", is now widely used in the semiconductor industry. The small detection area of TXRF enablesmapping measurement of contamination of the semiconductor surface, which is very useful in process characterization. However, the small detection area had been believed to limit rapid whole-surface analysis. Contrary to this general understanding, in this study we demonstrated that a new method, ...
Tópico(s): Electron and X-Ray Spectroscopy Techniques
2002 - American Chemical Society | Analytical Chemistry
Hiroshi Ryu, Tokutaro Tanaka, Seiji Yamamoto, Kenichi Uemura, Yasuo Takehara, Haruo Isoda,
Object. The detailed anatomy of intracranial structures has been studied mainly in cadavers, but the absence of cerebrospinal fluid and blood pressure in these models distorts normal spatial relationships. The authors investigated the rotation of the facial nerve (FN), superior vestibular nerve (SVN), inferior vestibular nerve (IVN), and cochlear nerve (CN) in the internal auditory canal (IAC) and cerebellopontine cistern in human volunteers and compared their results with those reported in cadaver studies. ...
Tópico(s): Meningioma and schwannoma management
1999 - American Association of Neurological Surgeons | Journal of neurosurgery
Haruaki Uchiyama, Shigeru Nishizawa, Akihiko Satoh, Tetsuo Yokoyama, Kenichi Uemura,
A 60-year-old female and a 66-year-old male presented with post-traumatic pituitary apoplexy associated with clinically asymptomatic pituitary macroadenoma manifesting as severe visual disturbance that had not developed immediately after the head injury. Skull radiography showed a unilateral linear occipital fracture. Magnetic resonance imaging revealed pituitary tumor with dumbbell-shaped suprasellar extension and fresh intratumoral hemorrhage. Transsphenoidal surgery was performed in the first ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
1999 - Japan Neurological Society | Neurologia medico-chirurgica
Shigeru Nishizawa, Yutaka Oki, Seiji Ohta, Naoki Yokota, Tetsuo Yokoyama, Kenichi Uemura,
OBJECTIVE The goal of surgical treatment for Cushing's disease is "endocrinological cure." The purpose of this study was to determine predictors for postoperative endocrinological cure in Cushing's disease. METHODS Postoperative endocrinological studies were evaluated in 18 patients with Cushing's disease who underwent transsphenoidal surgery for selective adenomectomy. Serum adrenocorticotropic hormone (ACTH) levels were measured by radioimmunoassay during the first week after surgery. One week after ...
Tópico(s): Adrenal and Paraganglionic Tumors
1999 - Lippincott Williams & Wilkins | Neurosurgery
Tetsuo Yokoyama, Kenji Sugiyama, Shigeru Nishizawa, N. Yokota, Seiji Ohta, Kenichi Uemura,
OBJECTIVE: A preliminary study of subthalamic nucleus (STN) stimulation was performed to determine its applicability for the treatment of gait and postural disturbances in Parkinson's disease. METHODS: Five Parkinson's disease patients with freezing gait and postural instability were selected for this study. Their ages ranged from 60 to 73 years (mean ± standard deviation, 65.6 ± 4.8 years). Semi-microelectrode recording was used to identify the STN and to place a chronic electrical stimulation electrode ...
Tópico(s): Transcranial Magnetic Stimulation Studies
1999 - Lippincott Williams & Wilkins | Neurosurgery
Tetsuo Yokoyama, Yoko Imamura, Kenji Sugiyama, Shigeru Nishizawa, Naoki Yokota, Seiji Ohta, Kenichi Uemura,
Pre- and postoperative cognitive function was evaluated in 25 patients with Parkinson's disease (PD) who underwent unilateral posteroventral pallidotomy (PVP) to clarify the effects of this operation on cognitive function.Cognitive function was assessed before surgery and 1 month and 3 months afterward by using a battery of neuropsychological tests consisting of orientation, digit span (forward and backward), digit learning, 5-minute memory of five words, similarities, serial sevens, animal name listing, ...
Tópico(s): Cognitive Functions and Memory
1999 - American Association of Neurological Surgeons | Journal of neurosurgery
Mamoru Tomida, Masaaki Muraki, Kenichi Uemura, Kenji Yamasaki,
We investigated the possibility of predicting the progression of traumatic epidural hematomas (EDHs) and subdural hematomas (SDHs), in the acute stage, by using postcontrast magnetic resonance imaging (MRI) with gadolinium-diethylenetriaminepentaacetic acid.From January 1990 through December 1996, 41 patients with 43 hematomas (21 EDHs and 22 SDHs) underwent postcontrast MRI within 24 hours after injury. T1-weighted MRI was performed by using the spin echo method, after the administration of 0.1 mmol/ ...
Tópico(s): Spinal Fractures and Fixation Techniques
1998 - Lippincott Williams & Wilkins | Neurosurgery
Hiroshi Ryu, Seiji Yamamoto, Kenji Sugiyama, Kenichi Uemura, T Miyamoto,
✓ It is generally accepted that hemifacial spasm (HFS) and trigeminal neuralgia are caused by compression of the facial nerve (seventh cranial nerve) or the trigeminal nerve (fifth cranial nerve) at the nerve's root exit (or entry) zone (REZ); thus, neurosurgeons generally perform neurovascular decompression at the REZ. Neurosurgeons tend to ignore vascular compression at distal portions of the seventh cranial nerve, even when found incidentally while performing neurovascular decompression at the REZ of ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
1998 - American Association of Neurological Surgeons | Journal of neurosurgery