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Revisão Acesso aberto Revisado por pares

Alexandros Stamatopoulos, Theodosios Stamatopoulos, Zakareya Gamie, Eustathios Kenanidis, Ricardo Ribeiro, Kenneth S. Rankin, Craig Gerrand, Kenny Dalgarno, Eleftherios Tsiridis,

Over the past few decades, there has been growing interest in understanding the molecular mechanisms of cancer pathogenesis and progression, as it is still associated with high morbidity and mortality. Current management of large bone sarcomas typically includes the complex therapeutic approach of limb salvage or sacrifice combined with pre- and postoperative multidrug chemotherapy and/or radiotherapy, and is still associated with high recurrence rates. The development of cellular strategies against ...

Tópico(s): Cancer Cells and Metastasis

2019 - Elsevier BV | Journal of bone oncology