Hasan Ejaz, Sonia Younas, Muhammad Usman Qamar, Kashaf Junaid, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Ayman Ali Mohammed Alameen, Mohammed Yagoub Mohammed Elamir, Naveed Ahmad, Sanaa S. Hamam, Eman H. Salem, Syed Nasir Abbas Bukhari,
Plasmid-mediated colistin resistance (Col-R) conferred by mcr genes endangers the last therapeutic option for multifarious β-lactamase-producing bacteria. The current study aimed to explore the mcr gene molecular epidemiology in extensively drug-resistant (XDR) bacteria. Col-R gram-negative bacterial strains were screened using a minimum inhibitory concentration (MIC) breakpoint ≥4 µg/mL. Resistant isolates were examined for mcr variants, extended-spectrum β-lactamase, AmpC, and carbapenemase genes ...
Tópico(s): Pneumonia and Respiratory Infections
2021 - Multidisciplinary Digital Publishing Institute | Antibiotics
Hasan Ejaz, Abdullah Alsrhani, Aizza Zafar, Humera Javed, Kashaf Junaid, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Zeeshan Ahmed, Sonia Younas,
The pandemic situation with the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from China has endangered human lives. Coronavirus disease 2019 (COVID-19) is presented with asymptomatic, mild, or severe pneumonia-like symptoms. COVID-19 patients with diabetes, chronic obstructive pulmonary disease (COPD), cardiovascular diseases (CVD), hypertension, malignancies, HIV, and other comorbidities could develop a life-threatening situation. SARS-CoV-2 utilizes ACE-2 receptors found ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Elsevier BV | Journal of Infection and Public Health
Kashaf Junaid, Hasan Ejaz, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Muhammad Ikram Ullah, Humaira Yasmeen, Sonia Younas, Sanaa S. Hamam, Abdul Rehman,
The third coronavirus outbreak in the last two decades has caused significant damage to the world's economy and community health. The highly contagious COVID-19 infection has affected millions of people to date and has led to hundreds of thousands of deaths worldwide. Aside from the highly infectious nature of SARS-CoV-2, the lack of a treatment or vaccine has been the main reason for its spread. Thus, it has become necessary to find alternative methods for controlling SARS-CoV-2. For the present ...
Tópico(s): Vitamin D Research Studies
2020 - Multidisciplinary Digital Publishing Institute | Nutrients
Hasan Ejaz, Kashaf Junaid, Humaira Yasmeen, Amina Naseer, Hafsa Alam, Sonia Younas, Muhammad Usman Qamar, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Naveed Ahmad, Syed Nasir Abbas Bukhari,
Foodborne pathogens have acquired the ability to produce biofilms to survive in hostile environments. This study evaluated biofilm formation, antimicrobial resistance (AMR), and heavy metal tolerance of bacteria isolated from dairy and non-dairy food products. We aseptically collected and processed 200 dairy and non-dairy food specimens in peptone broth, incubated them overnight at 37 °C, and sub-cultured them on various culture media. Bacterial growth was identified with biochemical tests and API ...
Tópico(s): Gut microbiota and health
2022 - Multidisciplinary Digital Publishing Institute | Foods
Produção Nacional
Revisado por pares
Haroon Ur Rashid, Nasir Ahmad, Mohnad Abdalla, Khalid Khan, Marco António Utrera Martines, Samah Shabana,
The catastrophe of the coronavirus continues from one part of the world to another, and hardly a country is left without its devastations. Millions of people were infected and several hundred thousand died of the COVID-19 pandemic across the world. There is no clear targeted drug therapy available for the treatment of the patients. The discovery of vaccines is not enough to curtail its spread and disastrous implications. An instantly qualifying approach is needed to utilize the current drugs and ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2021 - Elsevier BV | Journal of Molecular Structure
Mohammed Al Mansour, Elsadig Yousif Mohamed, Sawsan Abdalla, Khalid Medani, Waqas Sami, Ahmed Syed Meraj,
Complementary and Alternative Medicine (CAM) is a growing industry in the health care system, and the use of CAM is rapidly evolving. In the Kingdom of Saudi Arabia (KSA), little research has addressed the satisfaction, use and perception of medical students towards CAM. The objectives of the current study were to assess the level of medical students' satisfaction and perception towards studying CAM and to determine their self-use of different modalities of CAM. This descriptive study was conducted ...
Tópico(s): Acupuncture Treatment Research Studies
2015 - Elsevier BV | Journal of Taibah University Medical Sciences
Ayman Salih Omer Idris, Koua Faisal Hammad Mekky, Badr Eldin Elsonni Abdalla, Khalid Altom Ali,
This study was planned to evaluate the liver function in patients with type 2 diabetes mellitus by measuring aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transpeptidase (GGT), total protein and albumin. The study was carried out in Wad Medani, Abo Agla Diabetes Centre. 50 patients with type 2 diabetes mellitus (23 male and 27 female) were included in the study. Their ages ranged between 43 and 79 years. Thirty matched normal individuals were taken as control group. ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2011 - Academic Journals | International Journal of Nutrition and Metabolism
Naseem A. Charoo, Mohammad Ahmed Bashir, Enas Abdalla, Khalid Ibrahim Haj Ali,
Abstract This article describes the development and validation of a first derivative UV quantitative analytical method for determination of candesartan cilexetil in tablet dosage forms. A signal at 270.1 nm of the first derivative spectrum (ID270.1) was found adequate for quantification. The limit of quantification was 3.06 µg/ml. The linearity between ID270.1 nm and concentration of candesartan cilexetil in the range of 6.00–32.00 µg/ml presented a correlation coefficient of (r2) = 0.9990. The mean ...
Tópico(s): Pesticide Residue Analysis and Safety
2009 - Taylor & Francis | Analytical Letters
I. Adam, Osama Elhardello, M. O. Elhadi, Eltayeb AbdAlla, Khalid A Elmardi, Frans Herwig Jansen,
Although artemisinin and its derivatives are widely used for the treatment of malaria, they also have antischistosomal activity. In a small study in eastern Sudan, the effects of the treatment of uncomplicated, Plasmodium falciparum malaria with artesunate-sulfamethoxypyrazine-pyrimethamine (AS-SMP) and artemether-lumefantrine (AT-LU) on co-infections with Schistosoma mansoni were therefore investigated. Faecal samples from 14 of the 306 patients screened on presentation, at the start of a clinical ...
Tópico(s): Research on Leishmaniasis Studies
2007 - Maney Publishing | Annals of Tropical Medicine and Parasitology
Hasan Ejaz, Muhammad Usman Qamar, Kashaf Junaid, Sonia Younas, Zeeshan Taj, Syed Nasir Abbas Bukhari, Abualgasim Elgaili Abdalla, Khalid Omer Abdalla Abosalif, Naveed Ahmad, Zikria Saleem, Eman H. M. Salem,
The emergence of carbapenem-resistant Acinetobacter calcoaceticus-baumannii complex (CRACB) in clinical environments is a significant global concern. These critical pathogens have shown resistance to a broad spectrum of antibacterial drugs, including carbapenems, mostly due to the acquisition of various β-lactamase genes. Clinical samples (n = 1985) were collected aseptically from multiple sources and grown on blood and MacConkey agar. Isolates and antimicrobial susceptibility were confirmed with the ...
Tópico(s): Antibiotic Use and Resistance
2022 - Multidisciplinary Digital Publishing Institute | Antibiotics
Ammar Atif Abdalla, Muhammad Khalid,
Energy is present in every touch we make in our modern life. However, with the increase of energy-consuming devices, there is a burden to meet this demand with a clean power generation. Although solar and wind are considered as clean and renewable energy resources, many issues engender with their higher penetration into electricity grids. However, when renewable energy resources are integrated with battery energy storage systems (BESS), more smoothed and easily dispatchable power can be obtained. ...
Tópico(s): Smart Grid Energy Management
2020 - Institute of Electrical and Electronics Engineers | IEEE Access
Ammar Atif Abdalla, Muhammad Khalid,
Matching of the colossal energy demand with carbon-free resources originates a global challenge to produce and innovate advanced energy technologies that generate clean and friendly energy supplies without threatening our environment. Nevertheless, with the increase in the penetration from renewable energy resources like solar and wind farms many technical issues are presented typically; power stability, power quality, and frequency fluctuations. The aforementioned problems stem from the intermittent ...
Tópico(s): Smart Grid Energy Management
2020 - Institution of Engineering and Technology | IET Renewable Power Generation
Khaled Z. Alawneh, Majdi Al Qawasmeh, Liqaa Raffee, Bashar Abuzayed, Diab A. Bani Hani, Khalid Abdalla, Asma'a Mohammad Al-Mnayyis, Jehad Fataftah,
The burden of stroke can be substantially studied by establishing the functional consequences of stroke and its predictors on the population, economy and to guide rehabilitation efforts. This study aims to determine the subtypes, risk factors, and epidemiology of stroke in Jordan. Methods: A retrospective cohort study design was carried out to determine the risk factors and subtypes of stroke during 2017-2018. The study sample included 176 ischemic stroke patients of the King Abdullah University ...
Tópico(s): Neurological Disease Mechanisms and Treatments
2020 - Wolters Kluwer | Annals of Medicine and Surgery
Ahmed Mahmoud Sayed Sayedahmed, Abubakr Abdalla Abubakr Abdalla, Mohamed Khalid,
Coronavirus disease (COVID-19) is an infectious disease caused by a new coronavirus strain. The first case of the disease was reported as pneumonia of unknown cause in late December 2019, in Wuhan, China, and then the disease started to spread to other countries. This study aimed to assess the knowledge attitude and practice of the Sudanese population toward COVID-19. This cross-sectional online study was conducted among the Sudanese population. The Data was collected by using a self-administered ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Elsevier BV | Scientific African
Omima Mustafa, Khalid Abdalla, Aeshah AlAzmi, Naglla Elimam, Mohammed Burhan Abrar, Wasil Jastaniah,
Background Outcomes of relapsed/refractory childhood acute leukemia remain poor. We analyzed the safety/efficacy of fludarabine, cytarabine, and granulocyte colony stimulating factor, with/without idarubicin (FLAG ± IDA) as salvage therapy compared with recent published results of novel therapies. Methods This retrospective study included children aged 1 to 15 years with relapsed/refractory acute leukemia who received FLAG ± IDA salvage therapy from January 2000 to December 2014. Patients with infant ...
Tópico(s): CAR-T cell therapy research
2018 - SAGE Publishing | Journal of Oncology Pharmacy Practice
Nadir Abuzeid, Sadaf Kalsum, Richin John Koshy, Marie Larsson, Mikaela Glader, Henrik Andersson, Johanna Raffetseder, Elsje Pienaar, Daniel Eklund, Muddathir S. Alhassan, Haidar Abd Algadir, Waleed S. Koko, Thomas Schön, M. Ahmed Mesaik, Omer Mohamed Abdalla, Asaad Khalid, Maria Lerm,
The emergence of multidrug-resistant strains of Mycobacterium tuberculosis underscores the need for continuous development of new and efficient methods to determine the susceptibility of isolates of Mycobacterium tuberculosis in the search for novel antimycobacterial agents. Natural products constitute an important source of new drugs, and design and implementation of antimycobacterial susceptibility testing methods are necessary to evaluate the different extracts and compounds. In this study we ...
Tópico(s): Pharmacological Effects of Natural Compounds
2014 - Elsevier BV | Journal of Ethnopharmacology
Khalid Abdalla, A. Rahmat, Azizan Aziz,
Zinc phosphating is a chemical conversion process that has been widely used in industry for corrosion protection and primer for painting. In this investigation, the effect of activation treatment with nickel acetate on the microstructural evolution and corrosion resistance of the zinc phosphate coating on mild steel was studied. The chemical composition and morphology of the coatings were analyzed via scanning electron microscopy (SEM) and energy‐dispersive spectroscopy (EDS). The corrosion resistance ...
Tópico(s): Magnesium Alloys: Properties and Applications
2013 - Wiley | Materials and Corrosion
Khalid Abdalla, Azmi Rahmat, Azizan Aziz,
Tópico(s): Magnesium Alloys: Properties and Applications
2012 - Springer Science+Business Media | Journal of Coatings Technology and Research
M.I. Al-Jarallah, Fazal‐ur‐Rehman, Khalid Abdalla,
Abstract Short-term indoor radon measurements are used widely. Therefore, it is interesting to find out a correlation between these measurements and long-term measurements which reflect a better average radon concentration of individual measurement. To find the correlation between the two measurements of indoor radon concentrations at low radon levels, a study was carried out at 34 locations of King Fahd University of Petroleum & Minerals (KFUPM), Dhahran, Saudi Arabia using active and passive methods. ...
Tópico(s): Radiation Detection and Scintillator Technologies
2008 - Elsevier BV | Radiation Measurements
Abualgasim Elgaili Abdalla, Mahjoob Osman Mahjoob, Khalid Omer Abdalla Abosalif, Hasan Ejaz, Ayman Ali Mohammed Alameen, Tilal Elsaman,
Human cytomegalovirus (HCMV) can modulate the host cell microenvironment to cause latent infection and is therefore considered a major health concern in immunocompromised patients. HCMV-encoded microRNAs (miRs) have emerged as a key player in regulating the expression of the host cell and viral genes to induce latent infection. HCMV-encoded miRs can inhibit antiviral immune responses, such as proinflammatory mediators production, antigenic presentation, and apoptosis. In addition, HCMV miRs can reduce ...
Tópico(s): Extracellular vesicles in disease
2019 - Elsevier BV | Infection Genetics and Evolution
Hasan Ejaz, Kashaf Junaid, Sonia Younas, Abualgasim Elgaili Abdalla, Syed Nasir Abbas Bukhari, Khalid Omer Abdalla Abosalif, Naveed Ahmad, Zeeshan Ahmed, Manhal Ahmed Hamza, Naeem Anwar,
The monkeypox virus (MPXV) is the cause of a zoonotic infection similar to smallpox. Although it is endemic to Africa, it has recently begun to circulate in other parts of the world. In July 2022, the World Health Organization declared monkeypox an international public health emergency. This review aims to provide an overview of this neglected zoonotic pathogen. MPXV circulates as two distinct clades, the Central African and West African, with case fatality rates of 10.6% and 3.6%, respectively. ...
Tópico(s): Herpesvirus Infections and Treatments
2022 - Elsevier BV | Journal of Infection and Public Health
Bassem Elshahat, A.A. Naqvi, Khalid Abdalla,
Tópico(s): Medical Imaging Techniques and Applications
2007 - Springer Science+Business Media | Journal of Radioanalytical and Nuclear Chemistry
Khalid Abdalla, Azmi Rahmat, Azizan Aziz,
Zinc phosphate coating is commonly used for corrosion protection of metallic materials, mainly mild steel. In this study, influence of the pH of phosphating bath on the surface morphology and corrosion resistance of zinc phosphate coatings on mild steel was investigated. The phosphate layers were deposited on steel from phosphating bath at different pH values (1.75 ~ 2.75). The surface morphology and composition of phosphate coatings were investigated via scanning electron microscopy (SEM), and energy- ...
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
2012 - Trans Tech Publications | Advanced materials research
Khalid Abdalla Ali Abdel Rahim, Ahmed Hassanein, Heikal Abd El Hakim Abd El Azeiz,
One of the major health causing problems is contamination of drinking water sources with human pathogenic bacteria. Enteric bacteria such as Shigella, Salmonella and Escherichia coli are most enteric bacteria causing serious health problems. Occurrence of such bacteria infection, which may resist antibiotics, increases the seriousness of problem.The aim of this study was to examine the prevalence of some enteric bacteria (Shigella, Salmonella and E. coli) in addition to Pseudomonas. The antibiotic ...
Tópico(s): Enterobacteriaceae and Cronobacter Research
2015 - Brieflands | Jundishapur Journal of Microbiology
Abdelhakim Bouyahya, Saad Bakrim, Sara Aboulaghras, Kawtar El Kadri, Tarik Aanniz, Asaad Khalid, Ashraf N. Abdalla, Ahmed A. Abdallah, Chrismawan Ardianto, Long Chiau Ming, Nasreddine El Omari,
Oxidative stress results from a persistent imbalance in oxidation levels that promotes oxidants, playing a crucial role in the early and sustained phases of DNA damage and genomic and epigenetic instability, both of which are intricately linked to the development of tumors. The molecular pathways contributing to carcinogenesis in this context, particularly those related to double-strand and single-strand breaks in DNA, serve as indicators of DNA damage due to oxidation in cancer cases, as well as ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2024 - Elsevier BV | Biomedicine & Pharmacotherapy
Youssef Elouafy, Adil El Yadini, Salma Mortada, Mohamed Hnini, Hicham Harhar, Asaad Khalid, Ashraf N. Abdalla, Abdelhakim Bouyahya, Khang Wen Goh, Long Chiau Ming, My El Abbes Faouzi, Mohamed Tabyaouı,
Objective: To investigate the relationship between triterpenoid saponin content and antioxidant, antimicrobial, and α-glucosidase inhibitory activities of 70% ethanolic, butanolic, aqueous, supernate and precipitate extracts of Juglans regia leaves. Methods: Triterpenoid saponins of different Juglans regia leaf extracts were measured by the vanillin method. Antioxidant activity was evaluated against DPPH and ABTS free radicals. We also assessed α-glucosidase inhibitory and antimicrobial activities ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2023 - Medknow | Asian Pacific Journal of Tropical Biomedicine
Malek Alrobaian, Maram E. A. Abdalla Elsayed, Abdulaziz Khalid Alotaibi, Mosa Alharbi, William N. May, Donald U. Stone,
The purpose of the study is to determine the safety and efficacy of corneal collagen cross-linking for keratoconus in pediatric patients with and without vernal keratoconjunctivitis (VKC).This is a retrospective analysis of 89 eyes of 58 patients <18 years of age that underwent corneal collagen cross-linking for progressive keratoconus; inclusion criteria included a minimum of 2-year follow-up after cross-linking. The main outcomes measures included keratometry, pachymetry, vision, and complications ...
Tópico(s): Glaucoma and retinal disorders
2019 - Medknow | Middle East African Journal of Ophthalmology
Mohamed Gaber, Hazem M. Abu Shawish, Abdalla M. Khedr, Khalid I. Abed-Almonem,
A novel approach for determination of low concentrations of the preservative, benzalkonium chloride (BCCl), in pharmaceutical formulation constitutes is presented. New chemically modified carbon paste electrodes (CMCPEs) are developed. The first is based on an ion-association of BCCl with phosphomolybdic acid (PMA) as the ion-exchanger (BC–PM) dissolved in the mixed plasticizers dibutyl phthalate (DBP) and dioctyl sebacate (DOS) encoded sensor A. In the other electrode, encoded sensor B, the plasticizers ...
Tópico(s): Electrochemical Analysis and Applications
2012 - Elsevier BV | Materials Science and Engineering C
Hazem M. Abu Shawish, Abdalla M. Khedr, Khalid I. Abed-Almonem, Mohamed Gaber,
A comparative study was made between two designs of benzalkonium ion (Bz)-selective electrodes: a silver-coated (solid contact) called electrode A and a PVC membrane (liquid inner contact) called electrode B based on benzalkonium-phosphomolybdate (Bz-PM) as ion-exchanger complex. Electrode A has a linear dynamic range from 2.0×10−8 to 1.0×10−2 mol L−1, with a Nernstian slope of 60±0.3 mV/decade and a detection limit of 2.0×10−8 mol L−1. Electrode B shows linearity over the concentration range from 2. ...
Tópico(s): Electrochemical Analysis and Applications
2012 - Elsevier BV | Talanta
Tarig M. Abdelgader, Abdalla M. Ibrahim, Khalid A Elmardi, Sophie Githinji, Dejan Zurovac, Robert W. Snow, Abdisalan M. Noor,
Abstract Background Effective malaria case-management based on artemisinin-based combination therapy (ACT) and parasitological diagnosis is a major pillar within the 2007-2012 National Malaria Strategic Plan in the Sudan. Three years after the launch of the strategy a health facility survey was undertaken to evaluate case-management practices and readiness of the health facilities and health workers to implement a new malaria case-management strategy. Methods A cross-sectional, cluster sample survey ...
Tópico(s): Parasites and Host Interactions
2012 - BioMed Central | BMC Public Health