Yong‐Dae Kim, Sung‐Chul An, Tsunehiro Oyama, Toshihiro Kawamoto, Heon Kim,
... Activity in Cells Exposed to Low Level Chromium: Yong‐Dae Kim, et al. Department of Preventive Medicine, College of ...
Tópico(s): Trace Elements in Health
2003 - Wiley | Journal of Occupational Health
Yong‐Dae Kim, Chul‐Ho Lee, Hongmei Nan, Jong‐Won Kang, Heon Kim,
... and Urinary 1‐hydroxypyrene and 2‐naphthol Concentrations: Yong‐Dae Kim, et al. Department of Preventive Medicine, College of ...
Tópico(s): DNA Repair Mechanisms
2003 - Wiley | Journal of Occupational Health
Heon Kim, Yong-Dae Kim, Holik Lee, Toshihiro Kawamoto, Mihi Yang, Takahiko Katoh,
This paper describes a novel liquid chromatographic method for the quantitation of 2-naphthol in human urine. Urine samples were extracted after enzymatic hydrolysis of glucuronides and sulfates; 2-naphthol was then separated using reversed-phase high-performance liquid chromatography. The corresponding detection limits were 0.04 ng/ml for the standard sample in acetonitrile and 0.13 ng/ml for urine samples. The level of urinary 2-naphthol in 100 Korean shipyard workers was analyzed using this new ...
Tópico(s): Glutathione Transferases and Polymorphisms
1999 - Elsevier BV | Journal of Chromatography B Biomedical Sciences and Applications
Heon Kim, Yong‐Dae Kim, Soo-Hun Cho,
In our study, we estimated formaldehyde exposure levels of Korean medical students during their cadaver dissection practice hours. In addition, we examined the prevalence rates of formaldehyde-specific immunoglobulin E or immunoglobulin G antibodies and compared the results with the symptoms the students experienced as a result of formaldehyde exposure. There were 167 Korean medical students (i.e., subjects) aged 23.8+/-2.5 y (mean+/-standard deviation) and a control group of 67 premedical students ...
Tópico(s): Infection Control and Ventilation
1999 - Heldref Publications | Archives of Environmental Health An International Journal
Do-Hyeon Yang, Min Jae Shin, Minhee Kim, Yong‐Dae Kim, Heon Kim, Jae Sup Shin,
Tópico(s): Biosensors and Analytical Detection
2016 - Springer Science+Business Media | Microchimica Acta
Hong‐Seop Kho, Ji‐Youn Chang, Yoonyoung Kim, Yong‐Dae Kim,
Expression levels of MUC1 and TLR-2 were evaluated in burning mouth syndrome (BMS) patients and compared with those of controls and oral lichen planus (OLP) patients. The relationships between the expression levels of MUC1 and TLR-2 and levels of salivary pro-inflammatory cytokines were also investigated.Ten female BMS and ten female OLP patients were included. Ten female age-matched volunteers served as controls. RNA was isolated from stimulated whole saliva samples. Real-time PCR was used to quantify ...
Tópico(s): Oral Health Pathology and Treatment
2013 - Elsevier BV | Archives of Oral Biology
Chul Hyun Park, Tae-Jin Ju, Young-Woon Kim, Jinmyoung Dan, Jong-Yeon Kim, Yong‐Dae Kim, Jaesung Seo, So‐Young Park,
The present study examined the effect of the heme oxygenase (HO)-1 inducer hemin on skeletal muscle atrophy induced by single limb immobilization in mice. Immobilization was conducted in the left hindlimb of C57BL/6 mice for 1 week and the right hindlimb was used as a control. Hemin (30 mg/kg) was administered intraperitoneally once a day during the immobilization period. Gastrocnemius muscles were used for analysis. Muscle weight was measured to quantify degree of atrophy, and exhaustion treadmill ...
Tópico(s): Adipose Tissue and Metabolism
2013 - Elsevier BV | Life Sciences
Chang‐Hoon Kim, Jin Kook Kim, Hyun Jun Kim, Jin Hee Cho, Jung Soo Kim, Yong‐Dae Kim, Heung-Man Lee, Sung Wan Kim, Kyu‐Sup Cho, Sang Hag Lee, Chae‐Seo Rhee, Hun‐Jong Dhong, Ki‐Sang Rha, Joo‐Heon Yoon,
Purpose: To evaluate the efficacy and safety of once-daily ciclesonide in comparison to both levocetirizine alone, and a ciclesonide/levocetirizine combination in patients with seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR).Methods: Subjects exhibiting moderate to severe allergic rhinitis for longer than 1 year were randomized in an open-label, 3-arm, parallel group, multicenter study.Subjects received 200 µg ciclesonide, 5 mg levocetirizine, or a combination of both.Changes ...
Tópico(s): Dermatology and Skin Diseases
2015 - | Allergy Asthma and Immunology Research
Tae-Jin Ju, Woo-Young Kwon, Young-Woon Kim, Jong-Yeon Kim, Yong‐Dae Kim, In‐Kyu Lee, So‐Young Park,
The present study examined whether hemin could prevent the development of high-fat diet–induced insulin resistance in the liver and skeletal muscle using a hyperinsulinemic-euglycemic clamp. A four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels of insulin and lipid, which were reduced by hemin. High-fat diet reduced whole body glucose uptake, which were increased by hemin. Insulin-stimulated hepatic glucose production (HGP) was increased by high-fat diet, but ...
Tópico(s): Cannabis and Cannabinoid Research
2014 - Elsevier BV | Journal of Pharmacological Sciences
Yanwei Zhang, Sang‐Yong Eom, Dong‐Hyuk Yim, Young‐Jin Song, Hyo-Yung Yun, Joo‐Seung Park, Sei-Jin Youn, Byung-Sik Kim, Yong‐Dae Kim, Heon Kim,
AIM:To evaluate the relationship among Helicobacter pylori (H.pylori ) infection, CagA status, and dietary factors with RUNX3 promoter hypermethylation. METHODS:Gastric cancer tissue samples were collected from 184 South Korean patients.All patients were interviewed following a semi-quantitative food frequency questionnaire.The average frequencies of intake and portion sizes of 89 common food items were documented, and total intakes of calories, nutrients, vitamins, and minerals were calculated for ...
Tópico(s): Digestive system and related health
2013 - Baishideng Publishing Group | World Journal of Gastroenterology
Sang-Keun Bae, Hey-Na Cha, Tae-Jin Ju, Young-Woon Kim, Hee Sun Kim, Yong‐Dae Kim, Jinmyoung Dan, Jong‐Yeon Kim, Se-dong Kim, So‐Young Park,
The present study examined the effects of inducible nitric oxide synthase (iNOS) deficiency on skeletal muscle atrophy in single leg-immobilized iNOS knockout (KO) and wild-type (WT) mice. The left leg was immobilized for 1 wk, and the right leg was used as the control. Muscle weight and contraction-stimulated glucose uptake were reduced by immobilization in WT mice, which was accompanied with increased iNOS expression in skeletal muscle. Deficiency of iNOS attenuated muscle weight loss and the reduction ...
Tópico(s): Adipose Tissue and Metabolism
2012 - American Physiological Society | Journal of Applied Physiology
Si‐Youn Song, Hyun‐Jae Woo, Chang Hoon Bae, Young-Woon Kim, Yong‐Dae Kim,
Leptin is a pleiotropic hormone that regulates food intake and metabolic and endocrine functions. Serum leptin levels have been reported to be increased in patients with allergic rhinitis and nasal polyposis; however, the explanation for this is unclear. We aimed to demonstrate the differential expression of leptin receptors in normal human nasal mucosa and nasal polyps, and to elucidate the effects of leptin on mucin gene expression in human nasal polyp epithelial cells.Case-control and in vitro ...
Tópico(s): Allergic Rhinitis and Sensitization
2010 - Wiley | The Laryngoscope
Hye-Na Cha, Young-Woon Kim, Jong-Yeon Kim, Yong‐Dae Kim, In‐Hwan Song, Ki-Nam Min, So‐Young Park,
Tópico(s): Regulation of Appetite and Obesity
2010 - Elsevier BV | Experimental Gerontology
Seung‐Yup Ku, Jong Won Kang, Heon Kim, Yong Dae Kim, Byung Chul Jee, Chang Suk Suh, Young Min Choi, Jung Gu Kim, Shin Yong Moon, Seok Hyun Kim,
Age at menarche is known to be regulated by genetic and environmental factors. To date, no menarcheal data are available on North Korean women. In this cross-sectional survey, we investigated age at menarche and its possible influencing factors in North Korean refugees.Four hundred and eleven North Korean refugees were surveyed at a North Korean female refugee camp using a structured questionnaire within 3 months of immigration. Menarcheal age was requested and the data obtained were analysed with ...
Tópico(s): Psychosocial Factors Impacting Youth
2005 - Oxford University Press | Human Reproduction
Sang‐Yong Eom, Seonmi Hong, Dong‐Hyuk Yim, Hyojin Kwon, Dae‐Hoon Kim, Hyo‐Yung Yun, Young‐Jin Song, Sei-jin Youn, Taisun Hyun, Joo‐Seung Park, Byung Sik Kim, Yong‐Dae Kim, Heon Kim,
Abstract Although several studies reported genetic polymorphisms in protein kinase AMP ‐activated alpha 1 catalytic subunit ( PRKAA 1 ) and their associations with gastric cancer risk, few have evaluated associations between Helicobacter pylori infection and PRKAA 1 gene‐environment interactions. Here, we evaluated the effects of interactions between H. pylori infection and PRKAA 1 polymorphisms on gastric cancer risk in Koreans. In this hospital‐based case–control study, PRKAA 1 genotypes were analyzed ...
Tópico(s): Genetic factors in colorectal cancer
2016 - Wiley | Cancer Medicine
Heon Kim, Yong-Dae Kim, Jae Wook Choi,
Since type I allergy caused by specific IgE antibodies may play principal roles and IgG antibody-mediated reactions have been thought to be involved in some parts of the pathogenesis, this study was performed to investigate the role of IgE- or IgG-mediated hypersensitivity reactions in development of toluene diisocyanate (TDI) asthma in Korean workers. For 81 TDI spray painters, self-administrative questionnaires and direct interviews on respiratory symptoms, chest auscultation, and measurements ...
Tópico(s): Indoor Air Quality and Microbial Exposure
1997 - Elsevier BV | Environmental Research
Young‐Il Kim, Kwang-Min Yu, June‐Young Koh, Eun-Ha Kim, Se‐Mi Kim, Eun Ji Kim, Mark Anthony B. Casel, Rare Rollon, Seung‐Gyu Jang, Min‐Suk Song, Su‐Jin Park, Hye Won Jeong, Eung‐Gook Kim, Ok-Jun Lee, Yong‐Dae Kim, Younho Choi, Shin-Ae Lee, Youn Jung Choi, Su‐Hyung Park, Jae U. Jung, Young Ki Choi,
While the seroprevalence of SARS-CoV-2 in healthy people does not differ significantly among age groups, those aged 65 years or older exhibit strikingly higher COVID-19 mortality compared to younger individuals. To further understand differing COVID-19 manifestations in patients of different ages, three age groups of ferrets are infected with SARS-CoV-2. Although SARS-CoV-2 is isolated from all ferrets regardless of age, aged ferrets (≥3 years old) show higher viral loads, longer nasal virus shedding, ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2022 - Nature Portfolio | Nature Communications
Jongho Seo, Jin-Su Kim, Un‐Chang Jeong, Yong-Dae Kim, Young‐Cheol Kim, Hanmin Lee, Jae-Eung Oh,
Tópico(s): Wireless Power Transfer Systems
2016 - Springer Science+Business Media | Journal of the Korean Physical Society
Sang‐Yong Eom, Dong‐Hyuk Yim, Yanwei Zhang, Jung-Kuk Yun, Sun In Moon, Hyo‐Yung Yun, Young‐Jin Song, Sei-jin Youn, Taisun Hyun, Joo‐Seung Park, Byung Sik Kim, Jong‐Young Lee, Yong‐Dae Kim, Heon Kim,
Tópico(s): Carcinogens and Genotoxicity Assessment
2013 - Springer Science+Business Media | Cancer Causes & Control
Chang Hoon Bae, Jun Woo Kim, Sang Baik Ye, Si‐Youn Song, Young-Woon Kim, So‐Young Park, Yong‐Dae Kim,
Adenosine monophosphate-activated protein kinase (AMPK) is a well-known serine/threonine kinase that has been implicated in modulation of glucose and fatty acid metabolism. Recent reports have also implicated AMPK in modulation of mucin secretion. In this study, the effects and signaling pathways of AMPK on MUC5B expression were investigated in human NCI-H292 airway epithelial cells. Metformin, as an activator of AMPK, induced MUC5B expression in a dose-dependent manner. Compound C, as an inhibitor ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2011 - Elsevier BV | Biochemical and Biophysical Research Communications
Chang Hoon Bae, Jung Soo Kim, Si‐Youn Song, Young-Woon Kim, So‐Young Park, Yong‐Dae Kim,
The biologic actions of insulin-like growth factor-1(IGF-1) are associated with cell growth, differentiation, migration, and survival. IGF-1 constitutes the pathogenic factor in formation of nasal polyps and the regulatory factor in expression of mucins. However, the effect of IGF-1 on MUC8 and MUC5B expression has not been reported. Therefore, in this study, the effect and brief signaling pathway of IGF-1 on MUC8 and MUC5B expression were investigated in human airway epithelial cells. In mucin- ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2012 - Elsevier BV | Biochemical and Biophysical Research Communications
Dong‐Hun Kim, Bok-Kwon Lee, Yong‐Dae Kim, Sung‐Keun Rhee, Young‐Chang Kim,
Tópico(s): Bacteriophages and microbial interactions
2010 - Springer Science+Business Media | The Journal of Microbiology
Hyun‐Jae Woo, Woo Jong Yoo, Chang Hoon Bae, Si‐Youn Song, Young-Woon Kim, So‐Young Park, Yong‐Dae Kim,
Leptin, an adipocyte-secreted hormone that regulates food intake and metabolic response, has been recently reported to increase in the serum during inflammatory airway disease associated with mucus-hypersecretion. We investigated the effects of leptin on mucin expression in human airway epithelial cells and the signaling pathways. The expression of the leptin receptor was evaluated in human nasal mucosa and NCI-H292 cells. Leptin-induced expression of major respiratory mucins in NCI-H292 cells was ...
Tópico(s): Proteoglycans and glycosaminoglycans research
2010 - Informa | Experimental Lung Research
Heon Kim, Seungho Cho, Jeong-Woo Kang, Yong-Dae Kim, Hui-Jie Nan, Chih‐Hsin Lee, H. Lee, Toshihiro Kawamoto,
Tópico(s): Carcinogens and Genotoxicity Assessment
2000 - Springer Science+Business Media | International Archives of Occupational and Environmental Health
Sang‐Yong Eom, Yun-Sik Kim, Chung-Jong Lee, Chul‐Ho Lee, Yong‐Dae Kim, Heon Kim,
Paraoxonase 1 (PON1) hydrolyzes a number of toxic organophosphorous compounds and reduces lipid peroxide accumulation, and PON1 genetic polymorphisms in the coding region modulate serum PON1 activity.In this study, we investigated the association between 3 polymorphisms of PON1 located in intron 5 (17899insdelTT and 17974CT) and exon 6 (192QR) and serum PON1 activity.The genetic polymorphisms and serum activity of PON1 were analyzed in 153 healthy Koreans by using a direct sequencing assay and spectrophotometric ...
Tópico(s): Hibiscus Plant Research Studies
2011 - Korean Academy of Medical Sciences | Journal of Korean Medical Science
Sang‐Yong Eom, Jonghyuk Choi, Sanghyuk Bae, Ji-Ae Lim, Guen-Bae Kim, Seung‐Do Yu, Yangho Kim, Hyun‐Sul Lim, Bu‐Soon Son, Domyung Paek, Yong‐Dae Kim, Heon Kim, Mina Ha, Ho‐Jang Kwon,
Several epidemiological studies have reported an association between environmental pollution and various health conditions in individuals residing in industrial complexes. To evaluate the effects of pollution from industrial complex on human health, we performed a pooled analysis of environmental epidemiologic monitoring data for residents living near national industrial complexes in Korea. The respiratory and allergic symptoms and the prevalence of acute and chronic diseases, including cancer, ...
Tópico(s): Indoor Air Quality and Microbial Exposure
2018 - Korean Society of Environmental Helath and Toxicology | Environmental Health and Toxicology
Sang‐Yong Eom, Dong‐Hyuk Yim, Mingai Huang, Choong-Hee Park, Guen-Bae Kim, Seung‐Do Yu, Byung‐Sun Choi, Jung‐Duck Park, Yong‐Dae Kim, Heon Kim,
Abstract Purpose This cross-sectional study aimed to assess the effect of environmental cadmium (Cd) exposure and essential metal imbalance on renal tubular damage and oxidative stress in 979 adults living in a Cd-polluted area near an abandoned copper (Cu) refinery. Methods We analyzed urinary Cd concentrations, renal tubular damage and oxidative stress markers, such as beta-2 microglobulin (β2-MG) and N -acetyl-β- d -glucosaminidase (NAG) activity and urine malondialdehyde (MDA) levels. The serum copper- ...
Tópico(s): Trace Elements in Health
2019 - Springer Science+Business Media | International Archives of Occupational and Environmental Health
Kyoungwoo Kim, Eun‐Young Park, Kwan-Hee Lee, Jung‐Duck Park, Yong‐Dae Kim, Yun‐Chul Hong,
The mechanism of the adverse health effects of ambient particulate matter on humans has not been well-investigated despite many epidemiologic association studies. Measurement of personal exposure to particulate pollutants and relevant biological effect markers are necessary in order to investigate the mechanism of adverse health effects, particularly in fragile populations considered to be more susceptible to the effects of pollutants.We measured personal exposure to PM(2.5) and examined oxidative ...
Tópico(s): Air Quality Monitoring and Forecasting
2008 - Springer Science+Business Media | Environmental Health and Preventive Medicine
Hye Won Jeong, Se‐Mi Kim, Min Kyung Jung, Ji Yun Noh, Ji‐Seung Yoo, Eun-Ha Kim, Young‐Il Kim, Kwang-Min Yu, Seung‐Gyu Jang, Juryeon Gil, Mark Anthony B. Casel, Rollon Rare, Jeong Ho Choi, Hee‐Sung Kim, Jun Hyoung Kim, Jihye Um, Chaeyoon Kim, Yeonjae Kim, Bum Sik Chin, Sungmin Jung, Jun Yong Choi, Kyoung‐Ho Song, Yong‐Dae Kim, Jun-Sun Park, Joon Young Song, Eui‐Cheol Shin, Young Ki Choi,
Omicron has become the globally dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, creating additional challenges due to its ability to evade neutralization. Here, we report that neutralizing antibodies against Omicron variants are undetected following COVID-19 infection with ancestral or past SARS-CoV-2 variant viruses or after two-dose mRNA vaccination. Compared with two-dose vaccination, a three-dose vaccination course induces broad neutralizing antibody responses with ...
Tópico(s): Long-Term Effects of COVID-19
2022 - Elsevier BV | Cell Reports Medicine
Sang‐Yong Eom, Yan Wei Zhang, Sung‐Hoon Kim, Kang‐Hyeon Choe, Kye Young Lee, Jung‐Duck Park, Yun‐Chul Hong, Yong‐Dae Kim, Jong‐Won Kang, Heon Kim,
Tópico(s): Alcohol Consumption and Health Effects
2008 - Springer Science+Business Media | Cancer Causes & Control