W. H. M. Castro, Jörg Jerosch, R. Hepp, Klaus-Peter Schulitz,
This report details the authors' early experience using the automated percutaneous lumbar discectomy (APLD) procedure, developed by Onik et al., in 97 patients with a disc protrusion. In the evaluation of a herniated disc, we used computed tomography (CT) discography. According to the distribution of the dye inside the disc, five different disc types can be differentiated. With a follow-up after 3-7 months, the short-term outcomes of the first 40 APLD-treated patients varied, depending on the shape ...
Tópico(s): Musculoskeletal pain and rehabilitation
1992 - Lippincott Williams & Wilkins | Spine
Produção Nacional
Revisado por pares
Jan Keuter, Kevin Schwedtmann, Alexander Hepp, Klaus Bergander, Oliver Janka, Carsten Doerenkamp, Hellmut Eckert, Christian Mück‐Lichtenfeld, Felicitas Lips,
Abstract Reduktion des Tribromoamidosilans {N(SiMe 3 )Dipp}SiBr 3 mit Kaliumgraphit oder Magnesium führte zur Bildung eines Bicyclo[1.1.0]tetrasilatetraamids [Si 4 {N(SiMe 3 )Dipp} 4 ] ( 1 ). Das Si 4 ‐Motiv in 1 weist keine tetraedrische Struktur auf und hat zwei dreifach‐ und zwei vierfach‐koordinierte Siliciumatome. Die dreifach‐koordinierten Siliciumatome sind positiv und negativ polarisiert, was durch Messungen der magnetischen Suszeptibilität, EPR‐Messungen, DFT‐Rechnungen, 29 Si‐CP‐MAS‐NMR‐ und multinukleare ...
Tópico(s): Coordination Chemistry and Organometallics
2017 - Wiley | Angewandte Chemie
Produção Nacional
Revisado por pares
Jan Keuter, Kevin Schwedtmann, Alexander Hepp, Klaus Bergander, Oliver Janka, Carsten Doerenkamp, Hellmut Eckert, Christian Mück‐Lichtenfeld, Felicitas Lips,
Abstract The reduction of the tribromoamidosilane {N(SiMe 3 )Dipp}SiBr 3 (Dipp=2,6‐ i Pr 2 C 6 H 3 ) with potassium graphite or magnesium resulted in the formation of [Si 4 {N(SiMe 3 )Dipp} 4 ] ( 1 ), a bicyclo[1.1.0]tetrasilatetraamide. The Si 4 motif in 1 does not adopt a tetrahedral substructure and exhibits two three‐coordinate and two four‐coordinate silicon atoms. The electronic situation on the three‐coordinate silicon atoms is rationalized with positive and negative polarization based on EPR analysis, ...
Tópico(s): Coordination Chemistry and Organometallics
2017 - Wiley | Angewandte Chemie International Edition
Jan Keuter, Christian Schwermann, Alexander Hepp, Klaus Bergander, Jörn Droste, Michael Ryan Hansen, Nikos L. Doltsinis, Christian Mück‐Lichtenfeld, Felicitas Lips,
Thermal treatment of the bicyclo[1.1.0]tetrasilatetraamide [Si
Tópico(s): Molecular Junctions and Nanostructures
2020 - Royal Society of Chemistry | Chemical Science
Masao Hirokawa, Jacob Schach Møller, Itaru Sasaki,
... on the occasion of their 70th birthdays, and Klaus Hepp on the occasion of his 80th birthday.
Tópico(s): Cold Atom Physics and Bose-Einstein Condensates
2017 - Institute of Physics | Journal of Physics A Mathematical and Theoretical
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Olfactory and Sensory Function Studies
1970 - American Physiological Society | Journal of Neurophysiology
Albert F. Fuchs, Erich S. Luschei,
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Visual perception and processing mechanisms
1970 - American Physiological Society | Journal of Neurophysiology
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Retinal Development and Disorders
1969 - American Physiological Society | Journal of Neurophysiology
Erich S. Luschei, Albert F. Fuchs,
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Visual perception and processing mechanisms
1972 - American Physiological Society | Journal of Neurophysiology
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Glaucoma and retinal disorders
1977 - American Physiological Society | Journal of Neurophysiology
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Glaucoma and retinal disorders
1974 - American Physiological Society | Journal of Neurophysiology
... Neurons in the MonkeyHansjörg Scherberger, Jan-Harry Cabungcal, Klaus Hepp, Yasuo Suzuki, Dominik Straumann, and Volker Henn2071 August ...
Tópico(s): Glaucoma and retinal disorders
1979 - American Physiological Society | Journal of Neurophysiology
Stephan Braun, F. Hepp, Harald Sommer, Klaus Pantel,
Single micrometastatic tumor cells encased in mesenchymal tissues, such as bone marrow (BM), are regarded as suitable targets for adjuvant immunotherapy since they are easily accessible for both immunoglobulins and immune effector cells. However, the antigen profile of such cells, to which antibody therapy might be targeted, cannot be deduced from the antigen pattern of the primary tumor. To evaluate the antigen profile of disseminated cells found in BM aspirates from 20 breast cancer patients, we ...
Tópico(s): Immunotherapy and Immune Responses
1999 - Wiley | International Journal of Cancer
S. Landsgesell, K. Prokeš, B. Ouladdiaf, Bastian Klemke, O. Prokhnenko, B. Hepp, Klaus H. Kiefer, D. N. Argyriou,
In this paper we investigate the complex transformation of the magnetoelectric properties from the collinear A-type phase to the multiferroic noncollinear spin cycloid in the solid solution Nd${}_{1\ensuremath{-}x}$Y${}_{x}$MnO${}_{3}$ from compositions of $x=0.3$ to 0.55 in single crystal samples. Neutron diffraction experiments at the structural phase transition ($x=0.35$ to 0.45) reveal the coexistence of the A-type order and several incommensurate orders, varying with composition and temperature.
Tópico(s): Ferroelectric and Piezoelectric Materials
2012 - American Physical Society | Physical Review B
Christian Hepp, Martin Grabe, Klaus Hannemann,
Since its first introduction, it has always been a subject of research to find models for a meaningful approximation of the highly accurate but complex Boltzmann equation. In the kinetic Fokker–Planck (FP) approach, a FP operator in velocity space is employed to approximate the collision integral of the Boltzmann equation. Instead of directly solving the resulting FP equation, a Monte Carlo technique is used to model an associated random process. This approach leads to an efficient stochastic solution ...
Tópico(s): Optical properties and cooling technologies in crystalline materials
2020 - American Institute of Physics | Physics of Fluids
Stephan Braun, Manfred Mülller, F. Hepp, Günter Schlimok, Gert Riethmüller, Klaus Pantel,
Tópico(s): Cancer Diagnosis and Treatment
1998 - Oxford University Press | JNCI Journal of the National Cancer Institute
Brigitte Rack, Ulrich Andergassen, Julia Neugebauer, J Salmen, Philip Hepp, Harald Sommer, W. Lichtenegger, Klaus Friese, Matthias W. Beckmann, Dagmar Hauner, Hans Hauner, Wolfgang Janni,
Cohort trials have shown evidence that obesity and a low level of physical activity are not only associated with a higher risk of developing breast cancer, but also with an increased risk for recurrence and reduced survival in breast cancer patients. The SUCCESS C study is the first European trial to evaluate the effect of an intensive lifestyle intervention program on disease-free survival in women with early breast cancer and to examine the predictive value of selected biomarker candidates. A ...
Tópico(s): Cancer survivorship and care
2010 - Karger Publishers | Breast Care
Christian Hepp, Martin Grabe, Klaus Hannemann,
In recent years the kinetic Fokker-Planck approach for modeling gas flows has become increasingly popular. In the Fokker-Planck ansatz the collision integral of the Boltzmann equation is approximated by a Fokker-Planck operator in velocity space. Instead of solving the resulting Fokker-Planck equation directly, the underlying random process is modeled, which leads to an efficient stochastic solution algorithm. Despite the attention to the Fokker-Planck ansatz, the modeling of polyatomic gases has ...
Tópico(s): Thermal properties of materials
2020 - Elsevier BV | Journal of Computational Physics
Juraj Párajka, Alfred Paul Blaschke, Günter Blöschl, Klaus Haslinger, Gerold Hepp, Gregor Laaha, Wolfgang Schöner, Helene Trautvetter, Alberto Viglione, Matthias Zessner,
Abstract. The main objective of the paper is to understand the contributions to the uncertainty in low-flow projections resulting from hydrological model uncertainty and climate projection uncertainty. Model uncertainty is quantified by different parameterisations of a conceptual semi-distributed hydrologic model (TUWmodel) using 11 objective functions in three different decades (1976–1986, 1987–1997, 1998–2008), which allows for disentangling the effect of the objective function-related uncertainty ...
Tópico(s): Hydrology and Drought Analysis
2016 - Copernicus Publications | Hydrology and earth system sciences
Klaus Weinges, Michael Hepp, Hermann Jaggy,
Abstract Aus Blättern des Ginkgo‐Baumes wird ein neues Ginkgolid ( 5 ) isoliert, das wir als Ginkgolid J bezeichnen. Die Strukturaufklärung gelang sowohl mit spektroskopischen Methoden als auch durch chemischen Korrelation mit Ginkgolid C.
Tópico(s): Plant biochemistry and biosynthesis
1987 - Wiley | Liebigs Annalen der Chemie
Klaus Weinges, Michael Hepp, U. HUBER‐PATZ, Hans Rodewald, Hermann Irngartinger,
Abstract Die Titelverbindung 8b , ein Zwischenprodukt der beabsichtigten Partialsynthese von Bilobalid ( 10 ), wird durch Abbau von Ginkgolid A ( 1 ) gewonnen. Durch Röntgenstrukturanalyse von 14,15,16‐Trinorginkgolid A ( 7 ) wird die Struktur der Ringe B – E der Ginkgolide bestätigt.
Tópico(s): Neurological Disease Mechanisms and Treatments
1986 - Wiley | Liebigs Annalen der Chemie
Christian Hepp, Martin Grabe, Klaus Hannemann,
Kinetic Fokker–Planck (FP) methods for modeling rarefied gas flows have received increasing attention over the last few years. However, formulating such models for realistic multi-species gases is still an open subject of research. Therefore, in this letter, we develop a kinetic FP model for describing gas mixtures with particles interacting according to the variable hard-sphere interaction potential. In accordance with the kinetic FP framework, a stochastic solution algorithm is employed in order ...
Tópico(s): Optical properties and cooling technologies in crystalline materials
2020 - American Institute of Physics | AIP Advances
Klaus Weinges, Michael Hepp, Ursula Huber‐Platz, Hermann Irngartinger,
Abstract Bilobalid ( 1a ) zeigt auffallende biologische Wirkungen und ungewöhnliche chemische Eigenschaften. Ausgeprägt ist seine Tendenz, unter gelinden Acylierungsbedingungen zu den Diacyl‐Derivaten 2e–g der Spiro‐Verbindung 2a zu isomerisieren. Die Strukturen von Bilobalid ( 1a ) und 10,12‐Di‐ O ‐pivaloyl‐ iso ‐bilobalid ( 2f ) werden durch Röntgenbeugung bewiesen.
Tópico(s): Plant biochemistry and biosynthesis
1987 - Wiley | Liebigs Annalen der Chemie
Stephan Braun, Christian Schindlbeck, F. Hepp, Wolfgang Janni, Christina Kentenich, Gert Riethmüller, Klaus Pantel,
PURPOSE: Based on conventional tumor staging, primary ovarian cancer is viewed as an intraperitoneal disease that rarely spreads to extraperitoneal organs. However, autopsy studies reveal a much higher rate of occult metastasis, indicating that extraperitoneal spread occurs with much greater frequency than previously appreciated. Consequently, we investigated the incidence of early hematogenous dissemination and its association with distant disease-free and overall survival. PATIENTS AND METHODS: ...
Tópico(s): Cancer Cells and Metastasis
2001 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... of Jürg Fröhlich. Giovanni Felder, Gian Michele Graf, Klaus Hepp (eds). Pp. 857. £126.00. 2009. ISBN: 13- ...
Tópico(s): Surface and Thin Film Phenomena
2010 - Cambridge University Press | The Mathematical Gazette
Stephan Braun, Christina Kentenich, Wolfgang Janni, F. Hepp, J. De Waal, F Willgeroth, Harald Sommer, Klaus Pantel,
PURPOSE: There is an urgent need for markers that can predict the efficacy of adjuvant chemotherapy in patients with solid tumors. This study was designed to evaluate whether monitoring of micrometastases in bone marrow can predict the response to systemic chemotherapy in breast cancer. PATIENTS AND METHODS: Bone marrow aspirates of 59 newly diagnosed breast cancer patients with either inflammatory (n = 23) or advanced (> four nodes involved) disease (n = 36) were examined immunocytochemically with the monoclonal ...
Tópico(s): HER2/EGFR in Cancer Research
2000 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Werner Uhl, Lukas Keweloh, Alexander Hepp, Frank Stegemann, Marcus Layh, Klaus Bergander,
The P–H functionalized Al/P‐based frustrated Lewis pair (FLP) Mes(H)P–C[Al{CH(SiMe 3 ) 2 } 2 ]=C(H)– t Bu ( 3 ) has the typical functionality of FLPs with Lewis acidic and basic centers in a single molecule and is able to transfer the P bound H atom to activated substrates. Nevertheless, 3 reacted with NH 3 only by adduct formation with the N atom coordinated to Al ( 5 ). The relatively low basicity of the P atom prevented the formation of a hydrogen bridge between P and Al. Similarly, benzil and 3 afforded a simple ...
Tópico(s): Coordination Chemistry and Organometallics
2017 - Wiley | Zeitschrift für anorganische und allgemeine Chemie
Brigitte Rack, Julia Jückstöck, Maria Günthner-Biller, Ulrich Andergassen, Julia Neugebauer, Philip Hepp, A. Schoberth, Doris Mayr, Thomas Zwingers, Christian Schindlbeck, Klaus Friese, Wolfgang Janni,
Tópico(s): Glycosylation and Glycoproteins Research
2011 - Springer Science+Business Media | Archives of Gynecology and Obstetrics
Christian Hepp, Martin Grabe, Klaus Hannemann,
In this work we investigate the kinetic Fokker-Planck (FP) model [1, 2] concerning its applicability to simulate hyper-sonic, rarefied gas flow. As in the direct simulation Monte Carlo (DSMC) algorithm, the FP model simulates the stochastic motion of a set of particles through the computational domain which results in a simple coupling of both methods. No collisions must be calculated in the FP approach and so larger cell and time step sizes than by DSMC calculations can be used. Because of this, the ...
Tópico(s): Computational Fluid Dynamics and Aerodynamics
2019 - American Institute of Physics | AIP conference proceedings
... The Authors in Frontiers Nuno Macarico-da-Costa Klaus Hepp Kevan A Martin Google Nuno Macarico-da-Costa Klaus Hepp Kevan A Martin Google Scholar Nuno Macarico-da-Costa Klaus Hepp Kevan A Martin PubMed Nuno Macarico-da-Costa Klaus Hepp Kevan A Martin Related Article in Frontiers Google ...
Tópico(s): Functional Brain Connectivity Studies
2009 - Frontiers Media | Frontiers in Neuroscience