By Christopher Thomas Labour Reporter, By Craig Seton, By Tim Jones Labour Reporter, From Frank Vogl US Economics Correspondent, By Kenneth Gosling, From Patrick Brogan, From Tim Devlin Education Correspondent, From Bert Lodge, , By Clive Borrell Crime Correspondent, From Stewart Tendler, From Ronald Kershaw, By Peter Hennessy, By George Clark Political Correspondent, By Our Political Staff, From a Chess Correspondent, From Our Correspondent, From Ronald Faux, By Pat Healy Social Services Correspondent, By Our Social Services Correspondent, By Our Local Government Correspondent, By Neville Hodgkinson Social Policy Correspondent, From William Chislett, By Our Health Services Correspondent, From Charles Hargrove, From Harry Debelius, From Fred Emery, From Our Own Correspondent, From David Bonavia, From Nicholas Ashford, From Dessa Trevisan, From Robert Fisk, From Moshe Brilliant, From Peter Hazelhurst, By Peter West Rugby Correspondent, By Norman de Mesquita, By Rex Bellamy Squash Rackets Correspondent, By Michael Phillips Racing Correspondent, From John Hennessy, by Elizabeth Young, Katie Stewart, William Mann, John Percival, Paul Overy, Ned Chaillet, Irving Wardle, Stanley Sadie, Clive Bennett, Bernard Levin, Vilem Precan, PHS, David Spanier Diplomatic Correspondent, Stewart Tendler, N. BRITTON, , VICTORIA HURST, , PETER CRAWFORD, , FRED HARDMAN, , JANET JARVIS, , J. BOLINGBROKE, , DEREK EZRA, , J. ROTBLAT, , RON MONTAGUE, , JOHN STEBBING, , C. LE G. EATON, , MICHAL VYVYAN, , G. F. BROOKES, , KAHN, , E. R. HARDCASTLE, , W. A. M. EDWARDS, , W. C. WRIGHT, , ANTONY FLEW, , YVONNE SIEVE, , ENID LAKEMAN, , BRIAN TAYLOR, , From Phillip Howard, By Peter Hill Industrial Correspondent, By Caroline Atkinson, From John Earle, By Christopher Wilkins, By Desmond Quigley, By Malcolm Brown, By David Blake, From Frank Vogl, By Ray Maughan, By Ronald Emler, By Clifford Webb, By Patricia Tisdall, By Peter Hill, By Our Industrial Correspondent, WILFRED BROWN, , TIM FORTESCUE, , B. V. METHER, , A. C. A. HOPKINS, , BY THE FINANCIAL EDITOR, Adrienne Gleeson, Hugh Clayton, ,
... an ancient poem The Triumphs of Petrarch Coliseum, Klaus Schulze London Planetarium, The Ballad of Salomon Pavey Young ...
1977 - Gale Group | TDA
Klaus Schulze, Christian Richter, Karin Klatt, Ralf Ludwig,
... eine neue Synthese von Triazolidin-3-thionen Klaus Schulze, Klaus Schulze Karl-Marx-Universität, Sektion Chemie, Leipzig, DDR- ... 7010Search for more papers by this author Klaus Schulze, Klaus Schulze Karl-Marx-Universität, Sektion Chemie, Leipzig, DDR-7010Search ...
Tópico(s): Synthesis and biological activity
1988 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Hartmut Richter, Klaus Schulze, M. Mühlstädt,
... Universität, LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Institut für Organische Chemie der Karl-Marx- ... Universität, LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Institut für Organische Chemie der Karl-Marx-Universität, ...
Tópico(s): Chemical Reactions and Mechanisms
1968 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Manfred Müuhlstäudt, Klaus Schulze, Hartmut Richter,
... Universität LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität LeipzigSearch ... Universität LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität LeipzigSearch for ...
Tópico(s): Chemistry and Chemical Engineering
1970 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Wolfgang Dietrich, Klaus Schulze, M. Mühlstädt,
... Universität LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität LeipzigSearch ... Universität LeipzigSearch for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität LeipzigSearch for ...
Tópico(s): Asymmetric Synthesis and Catalysis
1975 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
... DDR-7010Search for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, Leipzig, ... DDR-7010Search for more papers by this authorKlaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, Leipzig, DDR- ...
Tópico(s): Asymmetric Synthesis and Catalysis
1988 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Klaus Schulze, Werner Mai, M. Mühlstädt,
... Umlagerung des γ-Chlormethallylrhodanids zum isomeren Chlorvinylsenföl Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR- ... 18Search for more papers by this author Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR-701 ...
Tópico(s): Organic Chemistry Cycloaddition Reactions
1977 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Klaus Schulze, Günter Haufe, Günther Köhler,
... in Gegenwart von Wasser, Eisessig oder Alkoholen Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR- ... 18Search for more papers by this author Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR-7010 ...
Tópico(s): Asymmetric Synthesis and Catalysis
1980 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
... von Hexen-(1)-diin-(3,5) (Vinyldiacetylen) Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität Leipzig, ... 18Search for more papers by this author Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität Leipzig, 701 ...
Tópico(s): Cancer Treatment and Pharmacology
1975 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Heike Bantel, Wolfram Domschke, Klaus Schulze‐Osthoff, Bernd Kaskas, Michael Gregor,
Bantel, Heike MD1,2; Domschke, Wolfram MD1; Schulze-Osthoff, Klaus PhD1; Kaskas, Bernd MD3; Gregor, Michael MD3Author Information
Tópico(s): Immune Response and Inflammation
2000 - Lippincott Williams & Wilkins | The American Journal of Gastroenterology
Klaus Schulze, Angela Vetter, Wolfgang Dietrich, M. Mühlstädt,
... 2-methylenpropan;† Synthese von 1,5-Diazacycloalkanen Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR- ... 18Search for more papers by this author Klaus Schulze, Klaus Schulze Sektion Chemie der Karl-Marx-Universität, DDR-701 ...
Tópico(s): Chemical Reactions and Mechanisms
1977 - Deutscher Verlag für Grundstoffindustrie | Zeitschrift für Chemie
Salma N. Tammam, Peter Nader Zaki Malak, Daphne Correa, Oliver C. Rothfuss, Hassan Mohamed El-Said Azzazy, Alf Lamprecht, Klaus Schulze‐Osthoff,
... M.E. Azzazy 2 , Alf Lamprecht 1, 4, * , Klaus Schulze-Osthoff 3, 5, * 1 Laboratory of Pharmaceutical Technology ... contributed equally and share senior authorship Correspondence to: Klaus Schulze-Osthoff, email: kso@uni-tuebingen.de Keywords: induced ...
Tópico(s): CRISPR and Genetic Engineering
2016 - Impact Journals LLC | Oncotarget
Tópico(s): Social Policy and Reform Studies
2004 - Springer Science+Business Media | KZfSS Kölner Zeitschrift für Soziologie und Sozialpsychologie
Dominik Krilleke, Esat Ucur, Dianne Pulte, Klaus Schulze‐Osthoff, Klaus‐Michael Debatin, Ingrid Herr,
The human leukemic T-cell line Jurkat was used to define the role of the cellular stress pathway with its key player kinase JNK in cancer therapy-induced apoptosis. JNK activity was inhibited by stable transfection with a dominant negative mutant of the upstream kinase JNKK/MKK4 or with the novel, potent and selective JNK1, -2 and -3 inhibitor SP600125. Inhibition of JNK activity delayed the onset of apoptosis induced by cisplatin, doxorubicin, gamma-irradiation and CD95-L but did not prevent apoptosis ...
Tópico(s): NF-κB Signaling Pathways
2003 - Wiley | International Journal of Cancer
Klaus Schulze Osthoff, Heike Bantel,
... effective interventions in ALF and other liver diseases. Klaus Schulze- Osthoff M.D*, Heike Bantel M.D , * Interfaculty ...
Tópico(s): Liver Disease Diagnosis and Treatment
2010 - Lippincott Williams & Wilkins | Hepatology
Marc Schuster, Rainer Glauben, Carlos Plaza‐Sirvent, Lisa Schreiber, Michaela Annemann, Stefan Floess, Anja A. Kühl, Linda K. Clayton, Tim Sparwasser, Klaus Schulze‐Osthoff, Klaus Pfeffer, Jochen Huehn, Britta Siegmund, Ingo Schmitz,
Summary Forkhead box P3 positive (Foxp3 + ) regulatory T (Treg) cells suppress immune responses and regulate peripheral tolerance. Here we show that the atypical inhibitor of NFκB (IκB) IκB NS drives Foxp3 expression via association with the promoter and the conserved noncoding sequence 3 (CNS3) of the Foxp3 locus. Consequently, IκB NS deficiency leads to a substantial reduction of Foxp3 + Treg cells in vivo and impaired Foxp3 induction upon transforming growth factor-β (TGF-β) treatment in vitro. Moreover, fewer ...
Tópico(s): Galectins and Cancer Biology
2012 - Cell Press | Immunity
Kristin Wahl, Martin Siegemund, Frank Lehner, Florian W. R. Vondran, Andreas K. Nüssler, Florian Länger, Till Krech, Roland E. Kontermann, Michael P. Manns, Klaus Schulze‐Osthoff, Klaus Pfizenmaier, Heike Bantel,
As the result of an increasing incidence and a prevalent therapy resistance of hepatocellular carcinoma (HCC), there is a strong need for novel strategies to enhance treatment responses in HCC. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising anticancer drug because it can selectively induce apoptosis in cancer cells, but not in healthy cells. Nevertheless, most tumor cells show TRAIL resistance, emphasizing the requirement for apoptosis-sensitizing ...
Tópico(s): Cancer Research and Treatments
2012 - Lippincott Williams & Wilkins | Hepatology
François Paris, Heike Grassmé, Aida Cremesti, Jonathan S. Zager, Yuman Fong, Adriana Haimovitz–Friedman, Zvi Fuks, Erich Gulbins, Richard Kolesnick,
... anti-caspase 8 (a kind gift of Dr. Klaus Schulze-Osthoff) (87); caspase 9 (Calbiochem 218794); inhibitor of ... anti-caspase 8 (a kind gift of Dr. Klaus Schulze-Osthoff) (87Belka C. Marini P. Lepple-Wienhues A. ...
Tópico(s): Erythrocyte Function and Pathophysiology
2001 - Elsevier BV | Journal of Biological Chemistry
Thorsten Schaefer, Hui Wang, Perihan Mir, Martina Konantz, Tamara C. Pereboom, Anna Paczulla, Britta Merz, Tanja Fehm, Sven Perner, Oliver C. Rothfuss, Lothar Kanz, Klaus Schulze‐Osthoff, Claudia Lengerke,
... 5 , Oliver C. Rothfuss 3 , Lothar Kanz 2 , Klaus Schulze-Osthoff 3, 6 , Claudia Lengerke 1, 2, 7 ...
Tópico(s): Epigenetics and DNA Methylation
2015 - Impact Journals LLC | Oncotarget
Marek Łoś, Ingrid Herr, Claudia Friesen, Simone Fulda, Klaus Schulze‐Osthoff, Klaus‐Michael Debatin,
Abstract The cytotoxic effect of anticancer drugs has been shown to involve induction of apoptosis. We report here that tumor cells resistant to CD95 (APO-1/Fas) -mediated apoptosis were cross-resistant to apoptosis-induced by anticancer drugs. Apoptosis induced in tumor cells by cytarabine, doxorubicin, and methotrexate required the activation of ICE/Ced-3 proteases (caspases), similarly to the CD95 system. After drug treatment, a strong increase of caspase activity was found that preceded cell death. ...
Tópico(s): interferon and immune responses
1997 - Elsevier BV | Blood
Stephan Hailfinger, Klaus Schulze‐Osthoff,
... Hailfinger: http://orcid.org/0000-0003-0276-2263 Klaus Schulze-Osthoff: http://orcid.org/0000-0003-1443-2720 ...
Tópico(s): Tryptophan and brain disorders
2021 - Elsevier BV | Journal of Investigative Dermatology
Ernst‐Detlef Schulze, Klaus Schilling, S. Nagarajah,
Tópico(s): Seed Germination and Physiology
1983 - Springer Science+Business Media | Oecologia
Michael Rettenmaier, Jonas Schulze, Klaus Bengler,
The communication of an automated vehicle (AV) with human road users can be realized by means of an external human–machine interface (eHMI), such as displays mounted on the AV’s surface. For this purpose, the amount of time needed for a human interaction partner to perceive the AV’s message and to act accordingly has to be taken into account. Any message displayed by an AV must satisfy minimum size requirements based on the dynamics of the road traffic and the time required by the human. This paper ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2020 - Multidisciplinary Digital Publishing Institute | Information
Juliane Menzel, Ronald Biemann, Alessa Longree, Berend Isermann, Knut Mai, Matthias B. Schulze, Klaus Abraham, Cornelia Weikert,
Abstract Vegetarian or vegan nutrition might influence inflammatory processes, thereby reducing the risk of chronic diseases. As the vegan diet becomes more importance in modern societies, data from the “Risks and Benefits of a Vegan Diet”-study has been used to investigate the associations of veganism with a comprehensive spectrum of inflammatory biomarkers, compared to omnivores. This cross-sectional study comprises 36 vegans and 36 omnivores (18 men and 18 women each) aged 30–60 years. No significant ...
Tópico(s): Nutrition, Genetics, and Disease
2020 - Nature Portfolio | Scientific Reports
Karl Heinrich Scholz, Björn Lengenfelder, Christian Thilo, Andreas Jeron, Stefan Stefanow, Uwe Janssens, Johann Bauersachs, P. Christian Schulze, Klaus Dieter Winter, Jörg Schröder, Jürgen vom Dahl, Nicolas von Beckerath, Karlheinz Seidl, Tim Friede, Thomas Meyer,
Abstract Aims To assess the impact of the lockdown due to coronavirus disease 2019 (COVID-19) on key quality indicators for the treatment of ST-segment elevation myocardial infarction (STEMI) patients. Methods Data were obtained from 41 hospitals participating in the prospective Feedback Intervention and Treatment Times in ST-Elevation Myocardial Infarction (FITT-STEMI) study, including 15,800 patients treated for acute STEMI from January 2017 to the end of March 2020. Results There was a 12.6% decrease ...
Tópico(s): Acute Myocardial Infarction Research
2020 - Springer Science+Business Media | Clinical Research in Cardiology
Philipp Schulze, Klaus H. Kaiser,
Tópico(s): Mass Spectrometry Techniques and Applications
1971 - Springer Science+Business Media | Chromatographia
Udo Jeschke, Hermann Walzel, Ioannis Mylonas, Panos Papadopoulos, Naim Shabani, Christina Kühn, Sandra Schulze, Klaus Friese, Uwe Karsten, David Anz, M. Kupka,
Mucin 1 (MUC1) is a glycoprotein in human endometrium and is abundant at the luminal epithelial surface in the receptive phase. It has a highly glycosylated ecto-domain that contains keratan sulfate chains, that disappears at the time of implantation. In addition, the glycoforms on MUC1 differ in fertile and infertile women. Therefore the aims of this study were investigations on glycosylation of MUC1 with the Thomsen-Friedenreich (TF) epitope on normal human endometrium throughout the menstrual cycle ...
Tópico(s): Reproductive System and Pregnancy
2009 - SAGE Publishing | Journal of Histochemistry & Cytochemistry
Bettina Tóth, Gitti Saadat, Alrun Geller, Christoph Scholz, Sandra Schulze, Klaus Friese, Udo Jeschke,
Tópico(s): Inflammatory mediators and NSAID effects
2008 - Springer Science+Business Media | Histochemistry and Cell Biology
Philipp Pohlenz, Marco Blessmann, Lars Oesterhelweg, Christan R. Habermann, Philipp G. C. Begemann, Christian Schmidgunst, Felix Blake, Dirk Schulze, Klaus Püschel, Rainer Schmelzle, Max Heiland,
The aim of our study was to demonstrate the image quality of the new device using human cadavers, extending the horizon of available imaging modalities in forensic medicine.Six human cadavers were examined, revealing C-arm data sets of the head, neck thorax, abdomen and pelvis. High-resolution mode was performed with 500 fluoroscopy shots during a 190 degrees orbital movement with a constant tube voltage of 100 kV and a current of 4.6 mA. Based on these data sets subsequent three-dimensional reconstructions ...
Tópico(s): Traumatic Ocular and Foreign Body Injuries
2007 - Elsevier BV | Forensic Science International
V. Minas, Ioannis Mylonas, B Schießl, Doris Mayr, Sandra Schulze, Klaus Friese, Udo Jeschke, Antonis Makrigiannakis,
Tópico(s): Erythrocyte Function and Pathophysiology
2007 - Springer Science+Business Media | Histochemistry and Cell Biology