Belkis Ezgi Arikan, Bianca M. van Kemenade, Katja Fiehler, Tilo Kircher, Knut Drewing, Benjamin Straube,
Abstract Adaptation to delays between actions and sensory feedback is important for efficiently interacting with our environment. Adaptation may rely on predictions of action-feedback pairing (motor-sensory component), or predictions of tactile-proprioceptive sensation from the action and sensory feedback of the action (inter-sensory component). Reliability of temporal information might differ across sensory feedback modalities (e.g. auditory or visual), which in turn influences adaptation. Here, we ...
Tópico(s): Action Observation and Synchronization
2021 - Nature Portfolio | Scientific Reports
Tobias Hertlein, Volker Sturm, Stefan Kircher, Thomas C. Basse-Lüsebrink, Daniel Haddad, Knut Ohlsen, Peter M. Jakob,
Background During the last years, 19F-MRI and perfluorocarbon nanoemulsion (PFC) emerged as a powerful contrast agent based MRI methodology to track cells and to visualize inflammation. We applied this new modality to visualize deep tissue abscesses during acute and chronic phase of inflammation caused by Staphylococcus aureus infection. Methodology and Principal Findings In this study, a murine thigh infection model was used to induce abscess formation and PFC or CLIO (cross linked ironoxides) was ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2011 - Public Library of Science | PLoS ONE
Benjamin Straube, Rasmus Schülke, Knut Drewing, Tilo Kircher, Bianca M. van Kemenade,
Tópico(s): Transcranial Magnetic Stimulation Studies
2017 - Springer Science+Business Media | Experimental Brain Research
Jörn Kircher, Knut Schwalba, A. Hedtmann,
Restoration of subscapularis function is essential for long-term maintenance of good clinical results for both traumatic and nontraumatic rotator cuff tears. The anatomic repair of partially and completely torn tendons from the footprint at the lesser tuberosity is the goal of surgical repair. The described technique, with a combination of an interlocking stitch and additional mattress sutures using a double-loaded suture anchor, provides reduction of the retracted tendon, sufficient pullout strength, ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2015 - Elsevier BV | Arthroscopy Techniques
Robert Lenz, Jörn Kircher, Knut Schwalba, Marc‐André Weber, Thomas Tischer,
Rotator cuff tears are one of the most common reasons for shoulder pain, and patients often present initially to general practitioners. However, subscapularis tears are especially difficult to diagnose and hence adequate therapy is often delayed. General practitioners or non-specialist orthopedic surgeons need reliable MRI findings to allow timely referral of patients to shoulder specialists. The purpose of this study was to determine the validity of the written MRI report of patients with arthroscopically ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2021 - Thieme Medical Publishers (Germany) | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Tiffany C. Ho, Boris A. Gutman, Elena Pozzi, Hans J. Grabe, Norbert Hosten, Katharina Wittfeld, Henry Völzke, Bernhard T. Baune, Udo Dannlowski, Katharina Förster, Dominik Grotegerd, Ronny Redlich, Andreas Jansen, Tilo Kircher, Axel Krug, Susanne Meinert, Igor Nenadić, Nils Opel, Richard Dinga, Dick J. Veltman, Knut Schnell, Ilya M. Veer, Henrik Walter, Ian H. Gotlib, Matthew D. Sacchet, André Alemán, Nynke A. Groenewold, Dan J. Stein, Meng Li, Martin Walter, Christopher R. K. Ching, Neda Jahanshad, Anjanibhargavi Ragothaman, Dmitry Isaev, Artemis Zavaliangos‐Petropulu, Paul M. Thompson, Philipp G. Sämann, Lianne Schmaal,
Alterations in regional subcortical brain volumes have been investigated as part of the efforts of an international consortium, ENIGMA, to identify reliable neural correlates of major depressive disorder (MDD). Given that subcortical structures are comprised of distinct subfields, we sought to build significantly from prior work by precisely mapping localized MDD-related differences in subcortical regions using shape analysis. In this meta-analysis of subcortical shape from the ENIGMA-MDD working ...
Tópico(s): Advanced Neuroimaging Techniques and Applications
2020 - Wiley | Human Brain Mapping
Axel Krug, Maurice Cabanis, Martin Pyka, Katharina Pauly, Henrik Walter, Martin W. Landsberg, N. Jon Shah, Georg Winterer, Wolfgang Wölwer, Francesco Musso, Bernhard Müller, Georg Wiedemann, Jutta Herrlich, Knut Schnell, Kai Vogeley, Leonhard Schilbach, Karin Langohr, Alexander M. Rapp, Stefan Klingberg, Tilo Kircher,
Decision-making is an everyday routine that entails several subprocesses. Decisions under uncertainty occur when either prior information is incomplete or the outcomes of the decision are unclear. The aim of the present study was to disentangle the neural correlates of information gathering as well as reaching a decision and to explore effects of uncertainty acceptance or avoidance in a large sample of healthy subjects. Sixty-four healthy volunteers performed a decision-making under uncertainty ...
Tópico(s): Neuroscience and Music Perception
2013 - Elsevier BV | Behavioural Brain Research
Hanna Remde, Laura Schmidt-Pennington, Miriam Reuter, Laura‐Sophie Landwehr, Marie M. Jensen, Harald Lahner, Otilia Kimpel, Barbara Altieri, Katharina Laubner, J. Schreiner, Joerg Bojunga, Stefan Kircher, Catarina Alisa Kunze, Anne Pohrt, Maria‐Veronica Teleanu, Daniel Hübschmann, Albrecht Stenzinger, Hanno Glimm, Stefan Fröhling, Martin Faßnacht, Knut Mai, Matthias Kroiß,
Clinical trials with immune checkpoint inhibitors (ICI) in adrenocortical carcinoma (ACC) have yielded contradictory results. We aimed to evaluate treatment response and safety of ICI in ACC in a real-life setting.Retrospective cohort study of 54 patients with advanced ACC receiving ICI as compassionate use at 6 German reference centres between 2016 and 2022.Objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS), overall survival (OS), and treatment-related adverse ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2023 - Oxford University Press | European Journal of Endocrinology
Leonardo Tozzi, Lisa Garczarek, Deborah Janowitz, Dan J. Stein, Katharina Wittfeld, Henrik Dobrowolny, Jim Lagopoulos, Sean N. Hatton, Ian B. Hickie, Angela Carballedo, Samantha J. Brooks, Daniella Vuletic, Anne Uhlmann, Ilya M. Veer, Henrik Walter, Robin Bülow, Henry Völzke, Johanna Klinger-König, Knut Schnell, Dieter Schoepf, Dominik Grotegerd, Nils Opel, Udo Dannlowski, Harald Kugel, Elisabeth Schramm, Carsten Konrad, Tilo Kircher, Dilara Jüksel, Igor Nenadić, Axel Krug, Tim Hahn, Olaf Steinsträter, Ronny Redlich, Dario Zaremba, Bartosz Zurowski, Cynthia H.Y. Fu, Danai Dima, James H. Cole, Hans J. Grabe, Colm G. Connolly, Tony T. Yang, Tiffany C. Ho, Kaja Z. LeWinn, Meng Li, Nynke A. Groenewold, Lauren E. Salminen, Martin Walter, Alan N. Simmons, Theo G.M. van Erp, Neda Jahanshad, Bernhard T. Baune, Nic J.A. van der Wee, Marie‐José van Tol, Brenda W.J.H. Penninx, Derrek P. Hibar, Paul M. Thompson, Dick J. Veltman, Lianne Schmaal, Thomas Frodl,
Abstract Background Childhood maltreatment (CM) plays an important role in the development of major depressive disorder (MDD). The aim of this study was to examine whether CM severity and type are associated with MDD-related brain alterations, and how they interact with sex and age. Methods Within the ENIGMA-MDD network, severity and subtypes of CM using the Childhood Trauma Questionnaire were assessed and structural magnetic resonance imaging data from patients with MDD and healthy controls were ...
Tópico(s): Prenatal Substance Exposure Effects
2019 - Cambridge University Press | Psychological Medicine
Maurice Cabanis, Martin Pyka, Stephanie Mehl, Bernhard Müller, Stephanie Loos-Jankowiak, Georg Winterer, Wolfgang Wölwer, Francesco Musso, Stefan Klingberg, Alexander M. Rapp, Karin Langohr, Georg Wiedemann, Jutta Herrlich, Henrik Walter, Michael Wagner, Knut Schnell, Kai Vogeley, Hanna Kockler, N. Jon Shah, Tony Stöcker, Renate Thienel, Katharina Pauly, Axel Krug, Tilo Kircher,
Attributions are constantly assigned in everyday life. A well-known phenomenon is the self-serving bias: that is, people’s tendency to attribute positive events to internal causes (themselves) and negative events to external causes (other persons/circumstances). Here, we investigated the neural correlates of the cognitive processes implicated in self-serving attributions using social situations that differed in their emotional saliences. We administered an attributional bias task during fMRI scanning ...
Tópico(s): Psychosomatic Disorders and Their Treatments
2013 - Springer Science+Business Media | Cognitive Affective & Behavioral Neuroscience
Produção Nacional
Revisado por pares
Eamonn Kennedy, Shashank Vadlamani, Hannah M. Lindsey, Pui‐Wa Lei, Mary Jo Pugh, Paul M. Thompson, David F. Tate, Frank G. Hillary, Emily L. Dennis, Elisabeth A. Wilde, Maheen M. Adamson, Martin Alda, Sílvia Alonso-Lana, Sonia Ambrogi, Tim Anderson, Celso Arango, Robert F. Asarnow, Mihai Avram, Rosa Ayesa‐Arriola, Talin Babikian, Nerisa Banaj, Laura Bird, Stefan Borgwardt, Amy Brodtmann, Katharina Brosch, Karen Caeyenberghs, Vince D. Calhoun, Nancy D. Chiaravalloti, David X. Cifu, Benedicto Crespo‐Facorro, John C. Dalrymple‐Alford, Kristen Dams-O’Connor, Udo Dannlowski, David Darby, Nicholas D. Davenport, John DeLuca, Covadonga M. Díaz‐Caneja, Seth G. Disner, Ekaterina Dobryakova, Stefan Ehrlich, Carrie Esopenko, Fabio Ferrarelli, Lea E. Frank, Carol E. Franz, Paola Fuentes‐Claramonte, Helen M. Genova, Christopher C. Giza, Janik Goltermann, Dominik Grotegerd, Marius Gruber, Alfonso Gutiérrez‐Zotes, Minji Ha, Jan Haavik, Charles H. Hinkin, Kristen R. Hoskinson, Daniela Hubl, Andrei Irimia, Andreas Jansen, Michael Kaess, Xiaojian Kang, Kimbra Kenney, Barbora Keřková, Mohamed Salah Khlif, Minah Kim, Jochen Kindler, Tilo Kircher, Karolína Knížková, Knut K. Kolskår, Denise Krch, William S. Kremen, Taylor Kuhn, Veena Kumari, Jun Soo Kwon, Roberto Langella, Sarah Laskowitz, Jungha Lee, Jean Lengenfelder, Spencer W. Liebel, Victoria Liou‐Johnson, Sara M. Lippa, Marianne Løvstad, Astri J. Lundervold, Cassandra Marotta, Craig A. Marquardt, Paulo Mattos, Ahmad Mayeli, Carrie R. McDonald, Susanne Meinert, Tracy R. Melzer, Jessica Merchán‐Naranjo, Chantal Michel, Rajendra A. Morey, Benson Mwangi, Daniel J. Myall, Igor Nenadić, Mary R. Newsome, Abraham Nunes, Terence J. O’Brien, Viola Oertel, John Ollinger, Alexander Olsen, Víctor Ortiz‐García de la Foz, Mustafa Ozmen, Heath Pardoe, Marise B. Parent, Fabrizio Piras, Federica Piras, Edith Pomarol‐Clotet, Jonathan Repple, Geneviève Richard, Jonathan Rodríguez, Mabel Rodríguez, Kelly Rootes-Murdy, Jared A. Rowland, Nicholas P. Ryan, Raymond Salvador, Anne‐Marthe Sanders, André Schmidt, Jair C. Soares, Gianfranco Spalleta, Filip Španiel, Alena Stasenko, Frederike Stein, Benjamin Straube, April D. Thames, Florian Thomas‐Odenthal, Sophia I. Thomopoulos, Erin B. Tone, Ivan J. Torres, Maya Troyanskaya, Jessica A. Turner, Kristine M. Ulrichsen, Guillermo E. Umpierrez, Elisabet Vilella, Lucy Vivash, William C. Walker, Emilio Werden, Lars T. Westlye, Krista Wild, Adrian Wroblewski, Mon‐Ju Wu, Glenn R. Wylie, Lakshmi N. Yatham, Giovana Zunta‐Soares,
Investigators in neuroscience have turned to Big Data to address replication and reliability issues by increasing sample size. These efforts unveil new questions about how to integrate data across distinct sources and instruments. The goal of this study was to link scores across common auditory verbal learning tasks (AVLTs). This international secondary analysis aggregated multisite raw data for AVLTs across 53 studies totaling 10,505 individuals. Using the ComBat-GAM algorithm, we isolated and removed ...
Tópico(s): Cognitive Science and Mapping
2024 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Eamonn Kennedy, Spencer W. Liebel, Hannah M. Lindsey, Shashank Vadlamani, Pui‐Wa Lei, Maheen M. Adamson, Martin Alda, Sílvia Alonso-Lana, Tim Anderson, Celso Arango, Robert F. Asarnow, Mihai Avram, Rosa Ayesa‐Arriola, Talin Babikian, Nerisa Banaj, Laura Bird, Stefan Borgwardt, Amy Brodtmann, Katharina Brosch, Karen Caeyenberghs, Vince D. Calhoun, Nancy D. Chiaravalloti, David X. Cifu, Benedicto Crespo‐Facorro, John C. Dalrymple‐Alford, Kristen Dams-O’Connor, Udo Dannlowski, David Darby, Nicholas D. Davenport, John DeLuca, Covadonga M. Díaz‐Caneja, Seth G. Disner, Ekaterina Dobryakova, Stefan Ehrlich, Carrie Esopenko, Fabio Ferrarelli, Lea E. Frank, Carol E. Franz, Paola Fuentes‐Claramonte, Helen M. Genova, Christopher C. Giza, Janik Goltermann, Dominik Grotegerd, Marius Gruber, Alfonso Gutiérrez‐Zotes, Minji Ha, Jan Haavik, Charles H. Hinkin, Kristen R. Hoskinson, Daniela Hubl, Andrei Irimia, Andreas Jansen, Michael Kaess, Xiaojian Kang, Kimbra Kenney, Barbora Keřková, Mohamed Salah Khlif, Minah Kim, Jochen Kindler, Tilo Kircher, Karolína Knížková, Knut K. Kolskår, Denise Krch, William S. Kremen, Taylor Kuhn, Veena Kumari, Jun-Soo Kwon, Roberto Langella, Sarah Laskowitz, Jungha Lee, Jean Lengenfelder, Victoria Liou‐Johnson, Sara M. Lippa, Marianne Løvstad, Astri J. Lundervold, Cassandra Marotta, Craig A. Marquardt, Paulo Mattos, Ahmad Mayeli, Carrie R. McDonald, Susanne Meinert, Tracy R. Melzer, Jessica Merchán‐Naranjo, Chantal Michel, Rajendra A. Morey, Benson Mwangi, Daniel J. Myall, Igor Nenadić, Mary R. Newsome, Abraham Nunes, Terence J. O’Brien, Viola Oertel, John Ollinger, Alexander Olsen, Víctor Ortiz‐García de la Foz, Mustafa Ozmen, Heath Pardoe, Marise B. Parent, Fabrizio Piras, Federica Piras, Edith Pomarol‐Clotet, Jonathan Repple, Geneviève Richard, Jonathan Rodríguez, Mabel Rodríguez, Kelly Rootes-Murdy, Jared A. Rowland, Nicholas P. Ryan, Raymond Salvador, Anne‐Marthe Sanders, André Schmidt, Jair C. Soares, Gianfranco Spalleta, Filip Španiel, Scott R. Sponheim, Alena Stasenko, Frederike Stein, Benjamin Straube, April D. Thames, Florian Thomas‐Odenthal, Sophia I. Thomopoulos, Erin B. Tone, Ivan J. Torres, Maya Troyanskaya, Jessica A. Turner, Kristine M. Ulrichsen, Guillermo E. Umpierrez, Daniela Vecchio, Elisabet Vilella, Lucy Vivash, William C. Walker, Emilio Werden, Lars T. Westlye, Krista Wild, Adrian Wroblewski, Mon‐Ju Wu, Glenn R. Wylie, Lakshmi N. Yatham, Giovana Zunta‐Soares, Paul M. Thompson, Mary Jo Pugh, David F. Tate, Frank G. Hillary, Elisabeth A. Wilde, Emily L. Dennis,
Deficits in memory performance have been linked to a wide range of neurological and neuropsychiatric conditions. While many studies have assessed the memory impacts of individual conditions, this study considers a broader perspective by evaluating how memory recall is differentially associated with nine common neuropsychiatric conditions using data drawn from 55 international studies, aggregating 15,883 unique participants aged 15–90. The effects of dementia, mild cognitive impairment, Parkinson’ ...
Tópico(s): Bipolar Disorder and Treatment
2024 - Multidisciplinary Digital Publishing Institute | Brain Sciences
Carolien G. F. de Kovel, Lyubomir I. Aftanas, André Alemán, Aaron Alexander‐Bloch, Bernhard T. Baune, Ivan Brack, Robin Bülow, Geraldo F. Busatto, Angela Carballedo, Colm G. Connolly, Kathryn R. Cullen, Udo Dannlowski, Christopher G. Davey, Danai Dima, Katharina Dohm, Tracy Erwin-Grabner, Thomas Frodl, Cynthia H.Y. Fu, Geoffrey B. Hall, David C. Glahn, Beata R. Godlewska, Ian H. Gotlib, Roberto Goya‐Maldonado, Hans J. Grabe, Nynke A. Groenewold, Dominik Grotegerd, Oliver Gruber, Mathew A. Harris, Ben J. Harrison, Sean N. Hatton, Ian B. Hickie, Tiffany C. Ho, Neda Jahanshad, Tilo Kircher, Bernd Krämer, Axel Krug, Jim Lagopoulos, Elisabeth J. Leehr, Meng Li, Frank P. MacMaster, Glenda MacQueen, Andrew M. McIntosh, Quinn McLellan, Sarah E. Medland, Bryon A. Mueller, Igor Nenadić, Evgeny Osipov, Martina Papmeyer, Marı́a J. Portella, Liesbeth Reneman, Pedro G. P. Rosa, Matthew D. Sacchet, Knut Schnell, Anouk Schrantee, Kang Sim, Egle Simulionyte, Lisa Sindermann, Aditya Singh, Dan J. Stein, Benjamin Ubani, Nic J.A. van der Wee, Steven J.A. van der Werff, Ilya M. Veer, Yolanda Vives‐Gilabert, Henry Völzke, Henrik Walter, Martin Walter, Mindy Westlund Schreiner, Heather C. Whalley, Nils R. Winter, Katharina Wittfeld, Tony T. Yang, Dilara Yüksel, Dario Zaremba, Paul M. Thompson, Dick J. Veltman, Lianne Schmaal, Clyde Francks,
Objective: Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated ...
Tópico(s): Neural and Behavioral Psychology Studies
2019 - American Psychiatric Association | American Journal of Psychiatry
Laura S. van Velzen, Sinéad Kelly, Dmitry Isaev, André Alemán, Lyubomir I. Aftanas, Jochen Bauer, Bernhard T. Baune, И. В. Брак, Angela Carballedo, Colm G. Connolly, Baptiste Couvy‐Duchesne, Kathryn R. Cullen, Konstantin V. Danilenko, Udo Dannlowski, Verena Enneking, Elena Filimonova, Katharina Förster, Thomas Frodl, Ian H. Gotlib, Nynke A. Groenewold, Dominik Grotegerd, Mathew A. Harris, Sean N. Hatton, Emma L. Hawkins, Ian B. Hickie, Tiffany C. Ho, Andreas Jansen, Tilo Kircher, Bonnie Klimes‐Dougan, Peter Kochunov, Axel Krug, Jim Lagopoulos, Renick Lee, Tristram A. Lett, Meng Li, Frank P. MacMaster, Nicholas G. Martin, Andrew M. McIntosh, Quinn McLellan, Susanne Meinert, Igor Nenadić, Evgeny Osipov, Brenda W.J.H. Penninx, Marı́a J. Portella, Jonathan Repple, Annerine Roos, Matthew D. Sacchet, Philipp G. Sämann, Knut Schnell, Xueyi Shen, Kang Sim, Dan J. Stein, Marie‐José van Tol, Alexander S. Tomyshev, Leonardo Tozzi, Ilya M. Veer, Robert Vermeiren, Yolanda Vives‐Gilabert, Henrik Walter, Martin Walter, Nic J.A. van der Wee, Steven J.A. van der Werff, Mindy Westlund Schreiner, Heather C. Whalley, Margaret J. Wright, Tony T. Yang, Alyssa H. Zhu, Dick J. Veltman, Paul M. Thompson, Neda Jahanshad, Lianne Schmaal,
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology of major depressive disorder (MDD). However, previous findings have been inconsistent, partially due to low statistical power and the heterogeneity of depression. In the largest multi-site study to date, we examined WM anisotropy and diffusivity in 1305 MDD patients and 1602 healthy controls (age range 12–88 years) from 20 samples worldwide, which included both adults and adolescents, within the MDD Working ...
Tópico(s): Advanced MRI Techniques and Applications
2019 - Springer Nature | Molecular Psychiatry
Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde, Janita Bralten, Derrek P. Hibar, Penelope A. Lind, Fabrizio Pizzagalli, Christopher R. K. Ching, Mary McMahon, Natalia Shatokhina, Leo Zsembik, Sophia I. Thomopoulos, Alyssa H. Zhu, Lachlan T. Strike, Ingrid Agartz, Saud Alhusaini, Marcio Almeida, Dag Alnæs, Inge K. Amlien, Micael Andersson, Tyler Ard, Nicola J. Armstrong, Allison E. Ashley‐Koch, Joshua R. Atkins, Manon Bernard, Rachel M. Brouwer, Elizabeth E.L. Buimer, Robin Bülow, Christian Bürger, Dara M. Cannon, M. Mallar Chakravarty, Qiang Chen, J. Cheung, Baptiste Couvy‐Duchesne, Anders M. Dale, Shareefa Dalvie, Tânia Kawasaki de Araujo, Greig I. de Zubicaray, Sonja M. C. de Zwarte, Anouk den Braber, Nhat Trung Doan, Katharina Dohm, Stefan Ehrlich, Hannah-Ruth Engelbrecht, Susanne Erk, Chun Fan, Iryna O. Fedko, Sonya Foley, Judith M. Ford, Masaki Fukunaga, Melanie E. Garrett, Tian Ge, Sudheer Giddaluru, Aaron L. Goldman, Melissa J. Green, Nynke A. Groenewold, Dominik Grotegerd, Tiril P. Gurholt, Boris A. Gutman, Narelle K. Hansell, Mathew A. Harris, Marc Harrison, Courtney C. Haswell, Michael A. Hauser, Stefan Herms, Dirk J. Heslenfeld, New Fei Ho, David Hoehn, Per Hoffmann, Laurena Holleran, Martine Hoogman, Jouke‐Jan Hottenga, Masashi Ikeda, Deborah Janowitz, Iris E. Jansen, Tianye Jia, Christiane Jockwitz, Ryota Kanai, Sherif Karama, Dalia Kasperavičiūtė, Tobias Kaufmann, Sinéad Kelly, Masataka Kikuchi, Marieke Klein, Michael Knapp, Annchen R. Knodt, Bernd Krämer, Max Lam, T. Lancaster, Phil H. Lee, Tristram A. Lett, Lindsay B. Lewis, Íscia Lopes‐Cendes, Michelle Luciano, Fabìo Macciardi, André F. Marquand, Samuel R. Mathias, Tracy R. Melzer, Yuri Milaneschi, Nazanin Mirza‐Schreiber, José C.V. Moreira, Thomas W. Mühleisen, Bertram Müller‐Myhsok, Pablo Najt, Soichiro Nakahara, Kwangsik Nho, Loes M. Olde Loohuis, Dimitri Papadopoulos Orfanos, John F. Pearson, Toni L. Pitcher, Benno Pütz, Yann Quidé, Anjanibhargavi Ragothaman, Faisal Rashid, William R. Reay, Ronny Redlich, Céline S. Reinbold, Jonathan Repple, Geneviève Richard, Brandalyn C. Riedel, Shannon L. Risacher, Cristiane S. Rocha, Nina Roth Mota, Lauren E. Salminen, Arvin Saremi, Andrew J. Saykin, Fenja Schlag, Lianne Schmaal, Peter R. Schofield, Rodrigo Secolin, Chin Yang Shapland, Li Shen, Jean Shin, Elena Shumskaya, Ida E. Sønderby, Emma Sprooten, Katherine E. Tansey, Alexander Teumer, Anbupalam Thalamuthu, Diana Tordesillas‐Gutiérrez, Jessica A. Turner, Anne Uhlmann, Costanza L. Vallerga, Dennis van der Meer, Marjolein M. J. van Donkelaar, Liza van Eijk, Theo G.M. van Erp, Neeltje E.M. van Haren, Daan van Rooij, Marie‐José van Tol, Jan H. Veldink, Ellen Verhoef, Esther Walton, Mingyuan Wang, Yunpeng Wang, Joanna M. Wardlaw, Wei Wen, Lars T. Westlye, Christopher D. Whelan, Stephanie H. Witt, Katharina Wittfeld, Christiane Wolf, Thomas Wolfers, Jing Qin Wu, Clarissa Lin Yasuda, Dario Zaremba, Zuo Zhang, Marcel P. Zwiers, Éric Artiges, Amelia A. Assareh, Rosa Ayesa‐Arriola, Ayşenil Belger, Christine L. Brandt, Gregory G. Brown, Sven Cichon, Joanne E. Curran, Gareth E. Davies, Franziska Degenhardt, Michelle F. Dennis, Bruno Dietsche, Srdjan Djurovic, Colin P. Doherty, Ryan Espiritu, Daniel Garijo, Yolanda Gil, Penny Gowland, Robert C. Green, Alexander N. Häusler, Walter Heindel, Beng‐Choon Ho, Wolfgang Hoffmann, Florian Holsboer, Georg Homuth, Norbert Hosten, Clifford R. Jack, MiHyun Jang, Andreas Jansen, Nathan A. Kimbrel, Knut K. Kolskår, Sanne Koops, Axel Krug, Kelvin O. Lim, Jurjen J. Luykx, Daniel H. Mathalon, Karen A. Mather, Venkata S. Mattay, Sarah Matthews, Jacqueline Mayoral-van Son, Sarah McEwen, Ingrid Melle, Derek W. Morris, Bryon A. Mueller, Matthias Nauck, Jan Egil Nordvik, Markus M. Nöthen, Daniel S. OʼLeary, Nils Opel, Marie‐Laure Paillère Martinot, G. Bruce Pike, Adrian Preda, Erin Burke Quinlan, Paul E. Rasser, Varun Ratnakar, Simone Reppermund, Vidar M. Steen, Paul A. Tooney, Fábio R. Torres, Dick J. Veltman, James Voyvodic, Robert Whelan, Tonya White, Hidenaga Yamamori, Hieab H.H. Adams, Joshua C. Bis, Stéphanie Debette, Charles DeCarli, Myriam Fornage, Vilmundur Guðnason, Edith Hofer, M. Arfan Ikram, Lenore J. Launer, W.T. Longstreth, Oscar L. López, Bernard Mazoyer, Thomas H. Mosley, Gennady V. Roshchupkin, Claudia L. Satizábal, Reinhold Schmidt, Sudha Seshadri, Qiong Yang, Marina K. M. Alvim, David Ames, Tim Anderson, Ole A. Andreassen, Alejandro Arias Väsquez, Mark E. Bastin, Bernhard T. Baune, Jean C. Beckham, John Blangero, Dorret I. Boomsma, Henry Brodaty, Han G. Brunner, Randy L. Buckner, Jan K. Buitelaar, Juan Bustillo, Wiepke Cahn, Murray J. Cairns, Vince D. Calhoun, Vaughan J. Carr, Xavier Caseras, Svenja Caspers, Gianpiero L. Cavalleri, Fernando Cendes, Aiden Corvin, Benedicto Crespo‐Facorro, John C. Dalrymple‐Alford, Udo Dannlowski, Eco J. C. de Geus, Ian J. Deary, Norman Delanty, Chantal Depondt, Sylvane Desrivières, Gary Donohoe, Thomas Espeseth, Guillén Fernández, Simon E. Fisher, Herta Flor, Andreas J. Forstner, Clyde Francks, Barbara Franke, David C. Glahn, Randy L. Gollub, Hans J. Grabe, Oliver Gruber, Asta K. Håberg,
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and ...
American Association for the Advancement of Science
Produção Nacional
Revisado por pares
Laura K. M. Han, Richard Dinga, Tim Hahn, Christopher R. K. Ching, Lisa T. Eyler, Lyubomir I. Aftanas, Moji Aghajani, André Alemán, Bernhard T. Baune, Klaus Berger, И. В. Брак, Geraldo F. Busatto, Angela Carballedo, Colm G. Connolly, Baptiste Couvy‐Duchesne, Kathryn R. Cullen, Udo Dannlowski, Christopher G. Davey, Danai Dima, Fábio Duran, Verena Enneking, Elena Filimonova, Stefan Frenzel, Thomas Frodl, Cynthia H.Y. Fu, Beata R. Godlewska, Ian H. Gotlib, Hans J. Grabe, Nynke A. Groenewold, Dominik Grotegerd, Oliver Gruber, Geoffrey B. Hall, Ben J. Harrison, Sean N. Hatton, Marco Hermesdorf, Ian B. Hickie, Tiffany C. Ho, Norbert Hosten, Andreas Jansen, Claas Kähler, Tilo Kircher, Bonnie Klimes‐Dougan, Bernd Krämer, Axel Krug, Jim Lagopoulos, Ramona Leenings, Frank P. MacMaster, Glenda MacQueen, Andrew M. McIntosh, Quinn McLellan, Katie L. McMahon, Sarah E. Medland, Bryon A. Mueller, Benson Mwangi, Evgeny Osipov, Marı́a J. Portella, Elena Pozzi, Liesbeth Reneman, Jonathan Repple, Pedro G. P. Rosa, Matthew D. Sacchet, Philipp G. Sämann, Knut Schnell, Anouk Schrantee, Egle Simulionyte, Jair C. Soares, Jens Sommer, Dan J. Stein, Olaf Steinsträter, Lachlan T. Strike, Sophia I. Thomopoulos, Marie‐José van Tol, Ilya M. Veer, Robert Vermeiren, Henrik Walter, Nic J.A. van der Wee, Steven J.A. van der Werff, Heather C. Whalley, Nils R. Winter, Katharina Wittfeld, Margaret J. Wright, Mon‐Ju Wu, Henry Völzke, Tony T. Yang, Vasileios Zannias, Greig I. de Zubicaray, Giovana Zunta‐Soares, Christoph Abé, Martin Alda, Ole A. Andreassen, Erlend Bøen, Caterina del Mar Bonnín, Erick J. Canales‐Rodríguez, Dara M. Cannon, Xavier Caseras, Tiffany M. Chaim‐Avancini, Torbjørn Elvsåshagen, Pauline Favre, Sonya Foley, Janice M. Fullerton, José Manuel Goikolea, Bartholomeus C. M. Haarman, Tomáš Hájek, Chantal Henry, Josselin Houenou, Fleur M. Howells, Martin Ingvar, Rayus Kuplicki, Beny Lafer, Mikael Landén, Rodrigo Machado‐Vieira, Ulrik Fredrik Malt, Colm McDonald, Philip B. Mitchell, Leila Nabulsi, Maria Concepción García Otaduy, Bronwyn J. Overs, Mircea Polosan, Edith Pomarol‐Clotet, Joaquim Raduà, Maria M. Rive, Gloria Roberts, Henricus G. Ruhé, Raymond Salvador, Salvador Sarró, Theodore D. Satterthwaite, Jonathan Savitz, Aart H. Schene, Peter R. Schofield, Maurício H. Serpa, Kang Sim, Márcio Gerhardt Soeiro‐de‐Souza, Ashley Sutherland, Henk Temmingh, Garrett Timmons, Anne Uhlmann, Eduard Vieta, Daniel H. Wolf, Marcus V. Zanetti, Neda Jahanshad, Paul M. Thompson, Dick J. Veltman, Brenda W.J.H. Penninx, André F. Marquand, James H. Cole, Lianne Schmaal,
Abstract Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in adult MDD patients, and whether this process is associated with clinical characteristics in a large multicenter international dataset. We performed a mega-analysis by pooling brain measures derived from T1-weighted MRI scans from 19 samples worldwide. Healthy brain aging was estimated by predicting chronological age (18– ...
Tópico(s): Tryptophan and brain disorders
2020 - Springer Nature | Molecular Psychiatry
Edith Hofer, Gennady V. Roshchupkin, Hieab H.H. Adams, Maria J. Knol, Honghuang Lin, Shuo Li, Habil Zare, Shahzad Ahmad, Nicola J. Armstrong, Claudia L. Satizábal, Manon Bernard, Joshua C. Bis, Nathan A. Gillespie, Michelle Luciano, Aniket Mishra, Markus Scholz, Alexander Teumer, Rui Xia, Xueqiu Jian, Thomas H. Mosley, Yasaman Saba, Lukas Pirpamer, Stephan Seiler, James T. Becker, Owen Carmichael, Jerome I. Rotter, Bruce M. Psaty, Oscar L. Lopez, Najaf Amin, Sven J. van der Lee, Qiong Yang, Jayandra J. Himali, Pauline Maillard, Alexa S. Beiser, Charles DeCarli, Sherif Karama, Lindsay B. Lewis, Mathew A. Harris, Mark E. Bastin, Ian J. Deary, A. Veronica Witte, Frauke Beyer, Markus Loeffler, Karen A. Mather, Peter R. Schofield, Anbupalam Thalamuthu, John B. Kwok, Margaret J. Wright, David Ames, Julian N. Trollor, Jiyang Jiang, Henry Brodaty, Wei Wen, Meike W. Vernooij, Albert Hofman, André G. Uitterlinden, Wiro J. Niessen, Katharina Wittfeld, Robin Bülow, Uwe Völker, Zdenka Pausová, G. Bruce Pike, Sophie Maingault, Fabrice Crivello, Christophe Tzourio, Philippe Amouyel, Bernard Mazoyer, Michael C. Neale, Carol E. Franz, Michael J. Lyons, Matthew S. Panizzon, Ole A. Andreassen, Anders M. Dale, Mark W. Logue, Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde, Janita Bralten, Derrek P. Hibar, Penelope A. Lind, Fabrizio Pizzagalli, Jason L. Stein, Paul M. Thompson, Sarah E. Medland, Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde, Janita Bralten, Derrek P. Hibar, Penelope A. Lind, Fabrizio Pizzagalli, Christopher R. K. Ching, Mary McMahon, Natalia Shatokhina, Leo Zsembik, Ingrid Agartz, Saud Alhusaini, Marcio A. A. Almeida, Dag Alnæs, Inge K. Amlien, Micael Andersson, Tyler Ard, Nicola J. Armstrong, Allison E. Ashley‐Koch, Manon Bernard, Rachel M. Brouwer, Elizabeth E.L. Buimer, Robin Bülow, Christian Bürger, Dara M. Cannon, M. Mallar Chakravarty, Qiang Chen, Joshua W. Cheung, Baptiste Couvy‐Duchesne, Anders M. Dale, Shareefa Dalvie, Tânia Kawasaki de Araujo, Greig I. de Zubicaray, Sonja M. C. de Zwarte, Anouk den Braber, Nhat Trung Doan, Katharina Dohm, Stefan Ehrlich, Hannah-Ruth Engelbrecht, Susanne Erk, Chun Fan, Iryna O. Fedko, Sonya Foley, Judith M. Ford, Masaki Fukunaga, Melanie E. Garrett, Tian Ge, Sudheer Giddaluru, Aaron L. Goldman, Nynke A. Groenewold, Dominik Grotegerd, Tiril P. Gurholt, Boris A. Gutman, Narelle K. Hansell, Mathew A. Harris, Marc Harrison, Courtney C. Haswell, Michael A. Hauser, Stefan Herms, Dirk J. Heslenfeld, New Fei Ho, David Hoehn, Per Hoffmann, Laurena Holleran, Martine Hoogman, Jouke‐Jan Hottenga, Masashi Ikeda, Deborah Janowitz, Iris E. Jansen, Tianye Jia, Christiane Jockwitz, Ryota Kanai, Sherif Karama, Dalia Kasperavičiūtė, Tobias Kaufmann, Sinéad Kelly, Masataka Kikuchi, Marieke Klein, Michael Knapp, Annchen R. Knodt, Bernd Krämer, Max Lam, T. Lancaster, Phil Hyu Lee, Tristram A. Lett, Lindsay B. Lewis, Íscia Lopes‐Cendes, Michelle Luciano, Fabìo Macciardi, André F. Marquand, Samuel R. Mathias, Tracy R. Melzer, Yuri Milaneschi, Nazanin Mirza‐Schreiber, José Carlos Vasques Moreira, Thomas W. Mühleisen, Bertram Müller-Myhsok, Pablo Najt, Soichiro Nakahara, Kwangsik Nho, Loes M. Olde Loohuis, Dimitri Papadopoulos Orfanos, John F. Pearson, Toni L. Pitcher, Benno Pütz, Anjanibhargavi Ragothaman, Faisal Rashid, Ronny Redlich, Céline S. Reinbold, Jonathan Repple, Geneviève Richard, Brandalyn C. Riedel, Shannon L. Risacher, Cristiane S. Rocha, Nina Roth Mota, Lauren E. Salminen, Arvin Saremi, Andrew J. Saykin, Fenja Schlag, Lianne Schmaal, Peter R. Schofield, Rodrigo Secolin, Chin Yang Shapland, Li Shen, Jean Shin, Alena Shumskaya, Ida E. Sønderby, Emma Sprooten, Lachlan T. Strike, Katherine E. Tansey, Alexander Teumer, Anbupalam Thalamuthu, Sophia I. Thomopoulos, Diana Tordesillas‐Gutiérrez, Jessica A. Turner, Anne Uhlmann, Costanza L. Vallerga, Dennis van der Meer, Marjolein M. J. van Donkelaar, Liza van Eijk, Theo G.M. van Erp, Neeltje E.M. van Haren, Daan van Rooij, Marie‐José van Tol, Jan H. Veldink, Ellen Verhoef, Esther Walton, Mingyuan Wang, Yunpeng Wang, Joanna M. Wardlaw, Wei Wen, Lars T. Westlye, Christopher D. Whelan, Stephanie H. Witt, Katharina Wittfeld, Christiane Wolf, Thomas Wolfers, Clarissa Lin Yasuda, Dario Zaremba, Zuo Zhang, Alyssa H. Zhu, Marcel P. Zwiers, Éric Artiges, Amelia A. Assareh, Rosa Ayesa‐Arriola, Ayşenil Belger, Christine L. Brandt, Gregory G. Brown, Sven Cichon, Joanne E. Curran, Gareth E. Davies, Franziska Degenhardt, Bruno Dietsche, Srdjan Djurovic, Colin P. Doherty, Ryan Espiritu, Daniel Garijo, Yolanda Gil, Penny Gowland, Robert C. Green, Alexander N. Häusler, Walter Heindel, Beng‐Choon Ho, Wolfgang Hoffmann, Florian Holsboer, Georg Homuth, Norbert Hosten, Clifford R. Jack, MiHyun Jang, Andreas Jansen, Knut Kolskår, Sanne Koops, Axel Krug, Kelvin O. Lim, Jurjen J. Luykx, Daniel H. Mathalon, Karen A. Mather, Venkata S. Mattay, Sarah Matthews, Jacqueline Mayoral-van Son, Sarah McEwen, Ingrid Melle, Derek W. Morris, Bryon A. Mueller, Matthias Nauck, Jan Egil Nordvik, Markus M. Nöthen, Daniel S. OʼLeary, Nils Opel,
Abstract Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurological and psychiatric diseases. Here we report heritability, genetic correlations and genome-wide associations of these cortical measures across the whole cortex, and in 34 anatomically predefined regions. Our discovery sample comprises 22,824 individuals from 20 cohorts within the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and the UK Biobank. We identify ...
Nature Portfolio
H Remde, L Schmidt-Pennington, M Reuter, L-S. Landwehr, Martin Bang Jensen, H Lahner, K Laubner, J Schreiner, J Bojunga, S Kircher, A Pohrt, Vozdvijenski M. ., D Hubschmann, A Stenzinger, H Glimm, S Frohling, M Fassnacht, Knut Mai, M. Kroiss,
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Tópico(s): Glioma Diagnosis and Treatment
2022 - Bioscientifica | Endocrine Abstracts
Katharina Pauly, I. Lengsfeld, Sabine Loos, Anna Rotarska-Jagiela, Francesco Musso, Angela Ciaramidaro, Thilo Kellermann, Knut Schnell, Hanna Kockler, J. Brinkmeyer, Maximilian Schwalm, Michael Sauder, Renate Thienel, Stefan Klingberg, Henrik Walter, Georg Wiedemann, Georg Winterer, Kai Vogeley, Bernhard Müller, Alexander M. Rapp, Tilo Kircher,
Tópico(s): Mental Health and Psychiatry
2009 - Oxford University Press | Schizophrenia Bulletin
... Dominik Endres, Dr. Mareike Grotheer, Prof. Dr. Tilo Kircher, Prof. Dr. Anna Schubö, Prof. Dr. Alexander Schütz, ...
Tópico(s): Psychology, Coaching, and Therapy
2022 - Hogrefe Verlag | Psychologische Rundschau