Mamoru Ohashi, Sho-Ichiro Kumasaki, Shosuki Yamamura, Koji Nakanishi, Hisashi Koike,
... A DEGRADATION PRODUCTMamoru Ohashi, Sho-Ichiro Kumasaki, Shosuki Yamamura, Koji Nakanishi, and Hisashi KoikeCite this: J. Am. Chem. ...
Tópico(s): Polyoxometalates: Synthesis and Applications
1959 - American Chemical Society | Journal of the American Chemical Society
Naoki Ohmiya, Masanao Nakamura, Takeshi Yamamura, Kôji Yamada, Asuka Nagura, Toru Yoshimura, Yoshiki Hirooka, Takayuki Matsumoto, Ichiro Hirata, Hidemi Goto,
Ohmiya, Naoki MD, PhD; Nakamura, Masanao MD, PhD; Yamamura, Takeshi MD; Yamada, Koji MD; Nagura, Asuka MD; Yoshimura, Toru MD; Hirooka, ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2013 - Lippincott Williams & Wilkins | Journal of Clinical Gastroenterology
... animation from Japan as anime. For example, when Yamamura Kōji’s Mt. Head (2002, Atamayama) was nominated for ...
Tópico(s): Hong Kong and Taiwan Politics
2014 - University of Minnesota Press | Mechademia Second Arc
Joji Tamaoka, Kazuki Takaoka, Hirokazu Hattori, Miho Ueta, Hanako Maeda, Michiyo Yamamura, Koji Yamanegi, Kazuma Noguchi, Hiromitsu Kishimoto,
Aging is a significant risk factor for the development of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Accumulating evidence suggests that bone aging is associated with oxidative stress (OS), and OS is associated with osteonecrosis. To elucidate the mechanisms of the onset of BRONJ, the present study focused on OS and the effects of treatment with the pro-oxidant DL-buthionine-(S,R)-sulfoximine (BSO), an oxidative stressor, on healing of a surgically induced penetrating injury of the palate. ...
Tópico(s): Osteomyelitis and Bone Disorders Research
2018 - Spandidos Publishing | Experimental and Therapeutic Medicine
Kosumi Yamada, Tsuyoshi Hasegawa, Eiichi Minami, Naoto Shibuya, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
The role of myrosinase (β-thioglucoside glucohydrolase, EC 3.2.3.1) in the phototropic response in radish hypocotyls was investigated. Unilateral illumination with blue light abruptly up-regulated the activity of myrosinase, which releases bioactive 4-methylthio-3-butenyl isothiocyanate (MTBI) from inactive 4-methylthio-3-butenyl glucosinolate (MTBG), in the illuminated halves of radish hypocotyls 10 min after onset of phototropic stimulation, peaking after 30 min and decreasing thereafter. The myrosinase ...
Tópico(s): Phytochemicals and Antioxidant Activities
2003 - Elsevier BV | Journal of Plant Physiology
Shuji Ohno, Kaori Tomita‐Yokotani, Seiji Kosemura, Mari Node, Toshisada Suzuki, Midori Amano, Kazuomi Yasui, Toshio Goto, Shosuke Yamamura, Koji Hasegawa,
Tópico(s): Seed Germination and Physiology
2001 - Elsevier BV | Phytochemistry
Sequence‐dependent DNA conformations of matrix attachment regions (MARs) available in a database were calculated using the wedge model, and compared with randomly chosen genes, promoters, enhancers and transposons. The MARs had a longer bent part and higher angle/helical turn than the other regions. It is known that some MAR sequences have A‐tracts that cause DNA bending, and we also found many A‐tracts in examined MARs. Furthermore, non‐random and clustered distribution of A‐tracts shown here gave ...
Tópico(s): Animal Genetics and Reproduction
2001 - Wiley | FEBS Letters
Tsuyoshi Hasegawa, Kosumi Yamada, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
Tópico(s): Phytochemicals and Antioxidant Activities
2000 - Elsevier BV | Phytochemistry
Kenichiro Yamamura, Koji Yomogita,
An efficient algorithm is proposed for finding all solutions of piecewise-linear (PWL) resistive circuits using linear programming (LP). This algorithm is based on a simple test (termed the LP test) for nonexistence of a solution to a system of PWL equations in a given region. In the LP test, the system of PWL equations is transformed into an LP problem, to which the simplex method is applied. Such an LP problem is obtained by surrounding the PWL functions by rectangles. It is shown that the LP test ...
Tópico(s): VLSI and FPGA Design Techniques
2000 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Circuits and Systems I Fundamental Theory and Applications
Hideki Fujii, Michihiro Iwaki, Hideki Hayashi, Hidenori Toyoda, Satoshi Oeda, Hideyuki Hyogo, Miwa Kawanaka, Asahiro Morishita, Kensuke Munekage, Kazuhito Kawata, Sakura Yamamura, Koji Sawada, Tatsuji Maeshiro, Hiroshi Tobita, Yuichi Yoshida, Masafumi Naito, Asuka Araki, Shingo Arakaki, Takumi Kawaguchi, Hidenao Noritake, Masafumi Ono, Tsutomu Masaki, Satoshi Yasuda, Eiichi Tomita, Masato Yoneda, Norifumi Kawada, Akihiro Tokushige, Yoshihiro Kamada, Hirokazu Takahashi, Shinichiro Ueda, Shinichi Aishima, Yoshio Sumida, Atsushi Nakajima, Takeshi Okanoue,
Background & Aims There are no detailed reports of clinical outcomes in Asian patients with nonalcoholic fatty liver disease (NAFLD) who undergo liver biopsy. We aimed to investigate the clinical outcomes of a large cohort of Asian patients with biopsy-proven NAFLD and evaluate the specific effects of nonalcoholic steatohepatitis and fibrosis stage. Methods This multicenter registry-based retrospective cohort study, called the CLIONE (Clinical Outcome Nonalcoholic Fatty Liver Disease) in Asia, included 1398 patients. ...
Tópico(s): Liver Disease and Transplantation
2022 - Elsevier BV | Clinical Gastroenterology and Hepatology
Yoshifumi Kudo, Ichiro Okano, Tomoaki Toyone, Akira Matsuoka, Hiroshi Maruyama, Ryo Yamamura, Koji Ishikawa, Chikara Hayakawa, Soji Tani, Masaya Sekimizu, Yushi Hoshino, Tomoyuki Ozawa, Toshiyuki Shirahata, Masayori Fujita, Yusuke Oshita, Haruka Emori, Hiroaki Omata, Katsunori Inagaki,
OBJECTIVE The purpose of this study was to compare the clinical results of revision interbody fusion surgery between lateral lumbar interbody fusion (LLIF) and posterior lumbar interbody fusion (PLIF) or transforaminal lumbar interbody fusion (TLIF) with propensity score (PS) adjustments and to investigate the efficacy of indirect decompression with LLIF in previously decompressed segments on the basis of radiological assessment. METHODS A retrospective study of patients who underwent revision surgery ...
Tópico(s): Musculoskeletal pain and rehabilitation
2020 - American Association of Neurological Surgeons | Neurosurgical FOCUS
Masaki Yamamura, Kōji Yamakawa, Yuki Okazaki, Tatsuya Nabeshima,
Abstract Both trans and cis isomers of azobenzene‐linked bis‐terpyridine ligand L1 were incorporated in rigid macrocycles linked by Fe II (tpy) 2 (tpy: terpyridine) units. The complex of the longer trans ‐ L1 is dinuclear [( trans ‐ L1 ) 2 ⋅ Fe II 2 ], whereas the complex of the shorter cis ‐ L1 is mononuclear [ cis ‐ L1⋅ Fe II ]. The complex cis ‐ L1⋅ Fe II was not only thermally stable but also photochemically inactive. These results indicate a perfectly locked state of cis ‐azobenzene. The stable macrocyclic structure of ...
Tópico(s): Supramolecular Chemistry and Complexes
2014 - Wiley | Chemistry - A European Journal
Hiroe Hara-Yamamura, Koji Nakashima, Asiful Hoque, Taro Miyoshi, Katsuki Kimura, Yoshimasa Watanabe, Satoshi Okabe,
DNA microarray-based transcriptome analysis with human hepatoma HepG2 cells was applied to evaluate the impacts of whole wastewater effluents from the membrane bioreactors (MBRs) and the activated sludge process (AS). In addition, the conventional bioassays (i.e., cytotoxicity tests and bioluminescence inhibition test), which were well-established for the evaluation of the overall effluent toxicity, were also performed for the same samples. Transcriptome analysis revealed that 2 to 926 genes, which ...
Tópico(s): Wastewater Treatment and Reuse
2013 - American Chemical Society | Environmental Science & Technology
Sharanjot Saini, Sumit Arora, Shahana Majid, Varahram Shahryari, Yi Chen, Guoren Deng, Soichiro Yamamura, Koji Ueno, Rajvir Dahiya,
Abstract Bladder cancer is often associated with recurrence and progression to invasive metastatic disease that have palliative therapeutic options. The use of traditional chemotherapeutic agents for bladder cancer management often suffers from toxicity and resistance concerns. This emphasizes the need for development of safer, natural, nontoxic compounds as chemotherapeutic/chemopreventive agents. Curcumin (diferuloylmethane) is a natural compound that has been known to possess anticancer properties ...
Tópico(s): Circular RNAs in diseases
2011 - American Association for Cancer Research | Cancer Prevention Research
Kazuto Yamauchi, Hidekazu Mimura, Takashi Kimura, Hirokatsu Yumoto, Soichiro Handa, Satoshi Matsuyama, Kenta Arima, Yasuhisa Sano, Kazuya Yamamura, Koji Inagaki, Hiroki Nakamori, Jangwoo Kim, Kenji Tamasaku, Yoshinori Nishino, Makina Yabashi, Tetsuya Ishikawa,
We have constructed an extremely precise optical system for hard-x-ray nanofocusing in a synchrotron radiation beamline. Precision multilayer mirrors were fabricated, tested, and employed as Kirkpatrick–Baez mirrors with a novel phase error compensator. In the phase compensator, an at-wavelength wavefront error sensing method based on x-ray interferometry and an in situ phase compensator mirror, which adaptively deforms with nanometer precision, were developed to satisfy the Rayleigh criterion to ...
Tópico(s): Laser-Plasma Interactions and Diagnostics
2011 - IOP Publishing | Journal of Physics Condensed Matter
Shahana Majid, Sharanjot Saini, Altaf A. Dar, Hiroshi Hirata, Varahram Shahryari, Yuichiro Tanaka, Soichiro Yamamura, Koji Ueno, Mohd Saif Zaman, Kamaldeep Singh, Inik Chang, Guoren Deng, Rajvir Dahiya,
Abstract The Src family of protein kinases (SFK) plays key roles in regulating fundamental cellular processes, including cell growth, differentiation, cell shape, migration, and survival, and specialized cell signals in various malignancies. The pleiotropic functions of SFKs in cancer make them promising targets for intervention. Here, we sought to investigate the role of microRNA-205 (miR-205) in inhibition of Src-mediated oncogenic pathways in renal cancer. We report that expression of miR-205 was ...
Tópico(s): Cancer-related molecular mechanisms research
2011 - American Association for Cancer Research | Cancer Research
Shahana Majid, Altaf A. Dar, Sharanjot Saini, Yi Chen, Varahram Shahryari, Jan Liu, Mohd Saif Zaman, Hiroshi Hirata, Soichiro Yamamura, Koji Ueno, Yuichiro Tanaka, Rajvir Dahiya,
The minichromosome maintenance (MCM) gene family is essential for DNA replication and is frequently upregulated in various cancers. Here, we examined the role of MCM2 in prostate cancer and the effect of microRNA-1296 (miR-1296), genistein, and trichostatin A (TSA) on the MCM complex. Profiling results showed that expression of MCM genes was higher in tumor samples. Genistein and TSA significantly downregulated the expression of all MCM genes. Genistein, TSA, and small interfering RNA duplexes caused ...
Tópico(s): Circular RNAs in diseases
2010 - American Association for Cancer Research | Cancer Research
Hiroshi Hirata, Yuji Hinoda, Koichi Nakajima, Ken Kawamoto, Nobuyuki Kikuno, Kazumori Kawakami, Soichiro Yamamura, Koji Ueno, Shahana Majid, Sharanjot Saini, Nobuhisa Ishii, Rajvir Dahiya,
Wnt/beta-catenin signaling is involved in renal cancer. DKK2, a Wnt antagonist, is silenced in some cancers, although its function has not been investigated. We hypothesized that DKK2 may be epigenetically silenced and inhibits progression of renal cell carcinoma (RCC).RCC cell lines and a normal kidney cell line were used for methylation and chromatin immunoprecipitation assays. To assess various functions of DKK2, we established stable DKK2-transfected cells and examined them with regard to cell ...
Tópico(s): Cancer-related gene regulation
2009 - American Association for Cancer Research | Clinical Cancer Research
Kaori Yokotani‐Tomita, Nobuharu Gotô, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
A potent growth-promoting allelopathic substance was located from the exudates of germinating Arabidopsis thaliana (line Shokei) seeds and identified by analysis of its spectral data as 2-O-l-rahmnopyranosyl-4-deoxy-α-l-threo-hex-4-enopyranosiduronoic acid (lepidimoic acid).
Tópico(s): Legume Nitrogen Fixing Symbiosis
1998 - Elsevier BV | Phytochemistry
Kosumi Yamada, Toyoaki Anai, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
The structure-activity relationship of lepidimoide and its analogues was investigated by means of the Amaranthus caudatus L. hypocotyl elongation test. In addition, the activities of α-d-galacturonic acid and l-(+)-rhamnose, which are component sugars of lepidimoide, were also studied. The carboxylic acid free type of lepidimoide showed growth-promoting activity as high as the original lepidimoide (sodium type). The acetylated compound showed considerably higher activity than lepidimoide, whereas ...
Tópico(s): Sesquiterpenes and Asteraceae Studies
1996 - Elsevier BV | Phytochemistry
Toyoaki Anai, Hiroko Aizawa, Nobuyuki Ohtake, Seiji Kosemura, Syosuke Yamamura, Koji Hasegawa,
Tópico(s): Weed Control and Herbicide Applications
1996 - Elsevier BV | Phytochemistry
Hideo Asada, Natsuko Okada, H Tei, Teiichi Yamamura, Koji Hashimoto, Kazuhiro Kondo, Koichi Yamanishi, Kunihiko Yoshikawa,
A 36-year-old man had a high titer of antibody to Epstein-Barr virus (EBV) and recurrent necrotizing papules and nodules on his face and oral mucosa. The disease was diagnosed as CD3+4− 8+ large granular lymphocyte leukemia of T-cell origin. Southern blot analysis demonstrated that EBV DNA was present in CD8+ lymphocytes; EBV antigens were also observed in these lymphocytes. These findings demonstrated that EBV latently infected the leukemic cells and may have played a role in the pathogenesis of ...
Tópico(s): Lymphoma Diagnosis and Treatment
1994 - Elsevier BV | Journal of the American Academy of Dermatology
Masako Hoshi-Sakoda, Kenji Usui, Kôzô Ishizuka, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
The structure-activity relationships of the naturally occurring auxin-inhibiting substance, 6-methoxy-2-benzoxazolinone, isolated from maize shoots, and its artificial analogues with respect to auxin activity and membrane-bound auxin-binding protein, were studied. 6-Isobutoxy-2-benzoxazolinone strongly inhibited auxin (1-naphthylacetic acid, NAA)-induced growth of etiolated maize coleoptile segments. 6-Isopropoxy-2-benzoxazolinone, 6-ethoxy-2-benzoxazolinone and 6-methoxy-2-benzoxazolinone showed ...
Tópico(s): Plant tissue culture and regeneration
1994 - Elsevier BV | Phytochemistry
Hisashi Kato‐Noguchi, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
A growth inhibitor which might be involved in light-induced growth inhibition of bean hypocotyl was isolated from light-grown dwarf bean shoots (Phaseolus vulgaris cv Morocco) and its structure was determined by spectral data as R-(−)-3-hydroxy-β-ionone. It inhibited the growth of hypocotyls of lettuce seedlings and hypocotyl segments of dwarf bean seedlings at concentrations greater than 0.03 μM, and its inhibitory activity was higher than ABA.
Tópico(s): Legume Nitrogen Fixing Symbiosis
1993 - Elsevier BV | Phytochemistry
Seji Kosemura, Shosuke Yamamura, Koji Hasegawa,
4-Methylthio-3-butenyl isothiocyanate as the direct precursor of raphanusanins has been isolated from the commercially available radish (Raphanus sativus L.), and some chemical studies on 4-methylthio-3-butenyl isothiocyanate (MTB-ITC) have been carried out, where it has been spontaneously converted into raphanusanins, phototropism-regulating substances of radish hypocotyls, in MeOH-H2O as well as in H2O solution.
Tópico(s): Plant Gene Expression Analysis
1993 - Elsevier BV | Tetrahedron Letters
Nobuyuki Harada, Hisahiro Hagiwara, Hiroshi Ono, Hisashi Uda, Shigeru Ohba, Mari Kubota, Shigeru Nishiyama, Shosuke Yamamura, Koji Hasegawa, Masako Sakoda,
Abstract The structures of raphanusanins A and B, growth inhibitors involved in phototropism of radish hypocotyls, were determined by X-ray crystallographic structure analysis and by spectral studies to be (3R*,6R*)- and (3R*,6S*)-3-[methoxy(methylthio)methyl]-2-pyrrolidinethione, respectively. Therefore, the previously proposed structure of these compounds of 2-piperidinethione skeleton should be revised.
Tópico(s): Bioactive Compounds and Antitumor Agents
1991 - Elsevier BV | Tetrahedron Letters
Naoki Ohmiya, Masanao Nakamura, Takeshi Yamamura, Kôji Yamada, Asuka Nagura, Toru Yoshimura, Yoshiki Hirooka, Ichiro Hirata, Hidemi Goto,
We classified intestinal lymphangiectasia (IL) into two categories, the white and non-white villi types, and evaluated their clinical characteristics and therapeutic responses.Of the 988 patients who underwent double-balloon enteroscopy, 14 consecutive patients (7 men and 7 women, median age at onset 34 years) were enrolled with immunohistochemically confirmed IL with protein-losing enteropathy.Enteroscopically the white villi type (n = 8) showed white plaques and white-tipped villi were scattered in ...
Tópico(s): Gastrointestinal disorders and treatments
2014 - Karger Publishers | Digestion
Kosumi Yamada, Hiroshi Matsumoto, Kentaro Ishizuka, Kensuke Miyamoto, Seiji Kosemura, S. YAMAMURA, Koji Hasegawa,
Tópico(s): Light effects on plants
1998 - Springer Science+Business Media | Journal of Plant Growth Regulation
Kensuke Miyamoto, Jun‐ya Ueda, Kosumi Yamada, Seiji Kosemura, S. YAMAMURA, Koji Hasegawa,
Tópico(s): Legume Nitrogen Fixing Symbiosis
1997 - Springer Science+Business Media | Journal of Plant Growth Regulation
Kensuke Miyamoto, Junichi Ueda, Kosumi Yamada, Seiji Kosemura, Shosuke Yamamura, Koji Hasegawa,
The effect of lepidimoide (Na 2-O-rhamnopyranosyl-4-deoxy-α-L-threo-hex-4-enopyranosiduronate) and its free carboxylic acid (hereafter referred as lepidimoic acid), on senescence in oat (Avena sativa L. cv. Victory I) leaf segments in the dark was studied. Lepidimoic acid inhibited loss of total chlorophyll in excised oat leaf segments during the initial phase of senescence. The loss of total chlorophyll was also retarded in the presence of 10 μmol/L kinetin. Lepidimoic acid preserved chlorophyll content ...
Tópico(s): Phytochemistry and Biological Activities
1997 - Elsevier BV | Journal of Plant Physiology