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Artigo Revisado por pares

Md. Anowar Hossain, Ryohei Nakano, Kôsuke Nakamura, Yuka Kimura,

... this author on: Oxford Academic PubMed Google Scholar Kosuke Nakamura, Kosuke Nakamura 1Department of Biofunctional Chemistry, Graduate School of Natural ...

Tópico(s): Phytase and its Applications

2009 - Oxford University Press | The Journal of Biochemistry

Artigo Acesso aberto Revisado por pares

Hiroshi Akiyama, Fumi Nakamura, C. Yamada, Kôsuke Nakamura, Osamu Nakajima, Hiroshi Kawakami, Naoki Harikai, Satoshi Furui, Kazumi Kitta, Reiko Teshima,

To screen for unauthorized genetically modified organisms (GMO) in the various crops, we developed a multiplex real-time polymerase chain reaction high-resolution melting-curve analysis method for the simultaneous qualitative detection of 35S promoter sequence of cauliflower mosaic virus (35SP) and the nopaline synthase terminator (NOST) in several crops. We selected suitable primer sets for the simultaneous detection of 35SP and NOST and designed the primer set for the detection of spiked ColE1 plasmid ...

Tópico(s): Transgenic Plants and Applications

2009 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin

Artigo

David E. Kandzari, Raymond R. Townsend, Kazuomi Kario, Felix Mahfoud, Michael A. Weber, Roland E. Schmieder, Stuart J. Pocock, Konstantinos Tsioufis, D. Konstantinidis, James W. Choi, Cara East, Lucas Lauder, Debbie L. Cohen, Taisei Kobayashi, Axel Schmid, David P. Lee, Adrian Ma, Joachim Weil, Tolga Agdirlioglu, Markus P. Schlaich, Sharad Shetty, Chandan Devireddy, Janice P. Lea, Jiro Aoki, Andrew S.P. Sharp, Richard Anderson, Martin Fahy, Vanessa DeBruin, Sandeep Brar, Michael Böhm, Yale Wang, Desmond Jay, Brent McLaurin, Carl Lomboy, Suhail Allaqaband, Fuad Jan, Bharat Gummadi, Marc R. Litt, Fidel Garcia, Jasvindar Singh, Angela L. Brown, James W. Choi, Ashley Paul, Andrew S.P. Sharp, James Coulson, Aravinda Nanjundappa, Ganpat G. Thakker, James Campbell, Benjamin Honton, Bruno Farah, Manesh R. Patel, Antonio Gutiérrez, Crystal C. Tyson, Laura P. Svetkey, Marat Fudim, Neha J. Pagidipati, Schuyler Jones, Sreekanth Vemulapalli, Chandan Devireddy, Ambar Kulshreshtha, Bryan Wells, Janice P. Lea, Bryan Batson, Robert B. Wilkins, Faisal Sharif, Abdullahi Mohamed Khair, Abhishek Wilson Pallippattu, Aishah Alhmoudi, Brian Gaffney, Christian Cawley, Colin Gorry, Hanan Hamed, Jennifer Carron, John Birrane, Liesbeth Rosseel, Mattia Lunardi, Michael J. Cronin, Myles McKittrick, Naeif Almagal, Noman Khalid, Qussai Shehahd, Shirjeel Shahzad, Simone Fezzi, Stanislav Tyulkin, Xavier Armario, Sanjit S. Jolly, Gordon Yip, Jon-David Schwalm, Michael Tsang, Shamir R. Mehta, Philipp Lurz, Christian Binner, Danilo Obradović, Florian Fahr, Ines Richter, Johannes Rotta detto Loria, Karl Fengler, Karl‐Philipp Rommel, Mateo Marín-Cuartas, Matthias Lerche, Philipp Hartung, Phillip Münch, Robert Höllriegel, Silke John, Satoru Otsuji, Hirofumi Kusumoto, Hiroto Tamaru, Kasumi Ishibuchi, Katsuyuki Hasegawa, Ken Sugimoto, Mikio Kakishita, Rui Ishii, Shin Takiuchi, Shingo Yasuda, Sho Nakabayashi, Wataru Yamamoto, Yorihiko Higashino, Yuji Shimatani, Yusuke Taniguchi, Konstantinos Tsioufis, Alexandros Kasiakogias, D. Konstantinidis, E. Andrikou, Κωνσταντίνος Κωνσταντίνου, Kyriakos Dimitriadis, Theodoros Kalos, Debbie L. Cohen, Garvey Rene, Jordana B. Cohen, Maria Bonanni, Matthew G. Denker, Rasi Wickramisinghe, Robert Wilensky, Tai Kobayashi, Venkatesh Y. Anjan, Yonghong Huan, Walter Herbert Haught, Joshua Krasnow, Alejandro Arias Väsquez, C. Gessler, Christopher Roth, David Drenning, Enrique M. Velasquez, George Soliman, James E. Murphy, Kaushik K. Jain, Michael Butler, Mihir Kanitkar, Phillip Laney, Ross J. Hunter, Shi-Chi Cheng, Thomas C. Wright, Walter Herbert Haught, Neil Chapman, Ahran Arnold, Alexandra N. Nowbar, Azara Janmohamed, Ben Corden, Christopher Cook, Christopher Rajkumar, Daniel Keene, David Thompson, Henry Seligman, James P. Howard, Justin E. Davies, Mark Sweeney, Matthew Shun‐Shin, Michael Foley, Nicholas M. Quaife, Rasha Al‐Lamee, Savvas Hadjiphilippou, Sayan Sen, Yousif Ahmad, Kazuomi Kario, Hayato Shimizu, Hirotaka Waki, Keisuke Narita, Masahisa Shimpo, Satoshi Hoshide, Takahiro Komori, Yukako Ogoyama, Yukiyo Ogata, Yusuke Oba, Mohanned Bisharat, Anton Lishmanov, Mohanned Bisharat, Travis Jeffords, Magdi Ghali, Beth Chia, Rachel Onsrud, Randolph Rough, Jiro Aoki, Daijiro Tomii, Fumiko Mori, Hosei Kikushima, Kai Ninomiya, Kazuyuki Yahagi, Kengo Tanabe, Kôsuke Nakamura, Kota Komiyama, Masaaki Nakase, Masahiko Asami, Naoto Setoguchi, Tetsu Tanaka, Yu Horiuchi, Yusuke Watanabe, Dmitriy N. Feldman, Geoffrey Bergman, Ines Sherifi, Luke Kim, Nivee Amin, Robert M. Minutello, S. Chiu Wong, Stephen McCullough, Richard D’Souza, Andrew S.P. Sharp, Hibba Kurdi, Richard D’Souza, Sarah Statton, Tony Watkinson, Barry Bertolet, Amit Gupta, Benjamin Blossom, Chris Bell, D.C. Hill, Francisco Sierra, James G. Johnson, John Estess, Joseph P. Adams, Katie McDuffie, Lee Ferguson, Nelson Little, Richard Dane Ballard, Roger A. Williams, Wanda Ikeda, William J. Calhoun, William L. Carroll, Avneet Singh, Benjamin J. Hirsh, Perwaiz Meraj, Rajiv Jauhar, Harsh Golwala, Jose Rueda, Kellie Graham, Ramsey Al-Hakim, Robert Rope, David E. Kandzari, Dariush Bahrami, Denise Reedus, Shukri David, Iram Rehman, Khalid Zakaria, Nishit Choksi, Samer Kazziha, Sarwan Kumar, Souheil Saba, Susan Steigerwalt, Yassir Sirajeldin, Omar Hyder, Herbert D. Aronow, Andrea Connors, Douglas Shemin, Clare Bent, Terry Levy, Vivek Kodoth, Markus P. Schlaich, Márcio Galindo Kiuchi, Revathy Carnagarin, Sharad Shetty, Sabino R. Torre, Howard Levitt, Lin Chen, Sarah Fan, Sergio Waxman, Wendy Porr, George Mangos, Brendan Smyth, Cathie Lane, Mark Sader, Kirit Patel, Anjani Rao, Brett Milford, Guneet Ahluwalia, Jaqueline Sennott, Justin Field, Nihar Jena, Stacy Loree, John Graham, Abdul Al‐Hesayen, Akshay Bagai, Junya Shite, Amane Kozuki, Atsushi Suzuki, Eri Masuko, Fumitaka Soga, Hiroyuki Asada,

Renal denervation (RDN) reduces blood pressure (BP) in patients with uncontrolled hypertension in the absence of antihypertensive medications.

Elsevier BV

Artigo Revisado por pares

Hidetaka Matsumoto, Junki Hoshino, Kosuke Nakamura, Tetsuhiro Nagashima, Hideo Akiyama,

Tópico(s): Retinal and Optic Conditions

2023 - Springer Science+Business Media | Graefe s Archive for Clinical and Experimental Ophthalmology

Artigo Revisado por pares

Satomi Shima, Kosuke Nakamura, Hiroshi Gotoda, Yuya Ohmichi, Shingo Matsuyama,

We study the formation mechanism of high-frequency combustion oscillations in a model rocket combustor from the viewpoints of symbolic dynamics and complex networks. The flow velocity fluctuations in the fuel injector generated by the pressure fluctuations in the combustor give rise to the periodic ignition of the unburnt fuel/oxidizer mixture, resulting in a significant change in the heat release rate fluctuations in the combustor. The heat release rate fluctuations drive the pressure fluctuations ...

Tópico(s): stochastic dynamics and bifurcation

2021 - American Institute of Physics | Physics of Fluids

Artigo Revisado por pares

R Yamada, Morio Sato, M. Kawabata, H Nakatsuka, Kôsuke Nakamura, Nobuo Kobayashi,

Five patients with segmental obstruction of the hepatic inferior vena cava associated with Budd-Chiari syndrome were successfully treated by percutaneous transluminal angioplasty using Grüntzig balloon catheters. Three or four balloons were used simultaneously to achieve sufficient dilatation. Long-term patency was obtained in all 5 cases without serious complications. This procedure may be applicable to other portions of the venous system as well.

Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis

1983 - Radiological Society of North America | Radiology

Artigo Revisado por pares

Y Nishimura, M Fushiki, Miki Yoshida, Kôsuke Nakamura, Michio Imai, Takeharu Ono, Shuji Morikawa, T Hatayama, Y Komatz,

The pullback pressure from the left renal vein (LRV) to the inferior vena cava was studied in 16 patients with left renal bleeding of unknown origin (group A), 15 patients with hematuria of miscellaneous laterality (group B), and nine control subjects (group C). The mean pressure gradients were 5.0 +/- 2.0 mm Hg (mean +/- SD) in group A, 1.9 +/- 1.0 mm Hg in group B, and 1.1 +/- 0.9 mm Hg in group C. The mean pressure gradient of group A was significantly higher than that of groups B and C (P less than .001). From the ...

Tópico(s): Renal and Vascular Pathologies

1986 - Radiological Society of North America | Radiology

Artigo Revisado por pares

Kôsuke Nakamura, Masami Inoue, Megumi Maeda, Ryohei Nakano, Katsutoshi Hosoi, Kazuhito Fujiyama, Yoshinobu Kimura,

In this study, we identified a gene encoding tomato ENGase (Endo-LE) using the gene information of rice ENGase, and expressed the Endo-LE protein in Escherichia coli. The substrate specificity of the recombinant Endo-LE was the same as that of the native enzyme, showing strong activity towards the high-mannose type N-glycans with the Manalpha1-2Manalpha1-3Manbeta1-4GlcNAcbeta1-4GlcNAc unit. Real-time PCR analysis revealed that the gene expression of Endo-LE did not vary significantly with the tomato ...

Tópico(s): Enzyme Production and Characterization

2009 - Oxford University Press | Bioscience Biotechnology and Biochemistry

Artigo Acesso aberto Revisado por pares

Md. Anowar Hossain, Kôsuke Nakamura, Yoshinobu Kimura,

In this study, we purified and characterized an alpha-mannosidase to homogeneity from mature red tomato fruits. Purified alpha-mannosidase (alpha-Man LE-1) gave two separate bands, of molecular masses of 70 kDa (L-subunit) and 47 kDa (S-subunit), on SDS-PAGE under non-reducing and reducing conditions. On the other hand, the molecular weight was estimated to be 230 kDa by gel filtration, indicating that alpha-Man LE-1 functions in a tetrameric structure in plant cells. The N-terminal sequence of the ...

Tópico(s): Biofuel production and bioconversion

2009 - Oxford University Press | Bioscience Biotechnology and Biochemistry

Artigo Revisado por pares

Kôsuke Nakamura, Masami Inoue, Takeo Yoshiie, Katsutoshi Hosoi, Yoshinobu Kimura,

In developing plants, free N-glycans occur ubiquitously at micromolar concentrations. Such oligosaccharides have been proposed to be signaling molecules in plant development. As a part of a study to elucidate the physiological roles of de-N-glycosylation machinery involved in fruit ripening, we analyzed changes in the amounts and structural features of free N-glycans in tomato fruits at four ripening stages. The amount of high-mannose type free N-glycans increased significantly in accordance with ...

Tópico(s): Carbohydrate Chemistry and Synthesis

2008 - Oxford University Press | Bioscience Biotechnology and Biochemistry

Artigo Revisado por pares

Yasutoshi Kido, Kimitoshi Sakamoto, Kôsuke Nakamura, Michiyo Harada, Takashi Suzuki, Yoshisada Yabu, Hiroyuki Saimoto, Fumiyuki Yamakura, Daijiro Ohmori, Anthony L. Moore, Shigeharu Harada, Kiyoshi Kita,

The trypanosome alternative oxidase (TAO) functions in the African trypanosomes as a cytochrome-independent terminal oxidase, which is essential for their survival in the mammalian host and as it does not exist in the mammalian host is considered to be a promising drug target for the treatment of trypanosomiasis. In the present study, recombinant TAO (rTAO) overexpressed in a haem-deficient Escherichia coli strain has been solubilized from E. coli membranes and purified to homogeneity in a stable ...

Tópico(s): Synthesis and Biological Evaluation

2010 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Bioenergetics

Artigo Revisado por pares

Md. Anowar Hossain, Ryohei Nakano, Kôsuke Nakamura, Md. Tofazzal Hossain, Yoshinobu Kimura,

It has been reported that acidic α-mannosidase activity increases during tomato fruit ripening, suggesting the turnover of N-glycoproteins is deeply associated with fruit ripening. As part of a study to reveal the relationship between the plant α-mannosidase activity and fruit maturation at the molecular level, we have already purified and characterized an α-mannosidase from tomato fruit (Hossain et al., Biosci. Biotechnol. Biochem. 2009;73:140-146). In this article, we describe the identification ...

Tópico(s): Polysaccharides and Plant Cell Walls

2010 - Oxford University Press | The Journal of Biochemistry

Artigo Revisado por pares

Mika Ikehata, Ryoko Yumoto, Kôsuke Nakamura, Junya Nagai, Mikihisa Takano,

Tópico(s): Caveolin-1 and cellular processes

2007 - Springer Science+Business Media | Pharmaceutical Research

Artigo Acesso aberto Revisado por pares

Kôsuke Nakamura, Hiroshi Akiyama, Kiyomi Ohmori, Yuki Takahashi, Reona Takabatake, Kazumi Kitta, Hiroyuki Nakazawa, Kazunari Kondo, Reiko Teshima,

Unauthorized genetically modified (GM) papaya (Carica papaya LINNAEUS) was detected in a commercially processed product, which included papaya as a major ingredient, in Japan. We identified the transgenic vector construct generated based on resistance to infection with the papaya ringspot virus (PRSV) YK strain. A specific detection method to qualitatively monitor papaya products for contamination with the GM papaya was developed using the real-time polymerase chain reaction.

Tópico(s): Insect Resistance and Genetics

2011 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin

Artigo

Kosuke Nakamura, Koji Ueda, Asahi Tomitaka, Tsutomu Yamada, Yasushi Takemura,

Magnetic nanoparticles are expected to be used as hyperthermia agents. The mechanism of self-heating of the magnetic nanoparticles under an ac magnetic field is different according to their size. In this study, the temperature rise for the ac/dc hysteresis loops of magnetic nanoparticles were evaluated to clarify the contribution of the Néel and Brownian relaxations to heat dissipation. The samples were dextran-coated magnetic iron oxide nanoparticles of different hydrodynamic diameters (40, 54, ...

Tópico(s): Iron oxide chemistry and applications

2012 - IEEE Magnetics Society | IEEE Transactions on Magnetics

Artigo Revisado por pares

Manabu Kanno, Kôsuke Nakamura, E. Kanai, Kunihito Hoki, Hirohiko Kono, Motohiko Tanaka,

There have been a growing number of articles that report dramatic improvements in the experimental performance of chemical reactions by microwave irradiation compared to that under conventional heating conditions. We theoretically examined whether nonthermal microwave effects on intramolecular reactions exist or not, in particular, on Newman-Kwart rearrangements and intramolecular Diels-Alder reactions. The reaction rates of the former calculated by the transition state theory, which consider only ...

Tópico(s): Ammonia Synthesis and Nitrogen Reduction

2012 - American Chemical Society | The Journal of Physical Chemistry A

Artigo Revisado por pares

Junichi Mano, Mioko Harada, Reona Takabatake, Satoshi Furui, Kazumi Kitta, Kôsuke Nakamura, Hiroshi Akiyama, Reiko Teshima, Hiromichi Noritake, Shuko Hatano, Satoshi Futo, Yasutaka Minegishi, Tayoshi Iizuka,

Abstract We have developed a real-time PCR array method to comprehensively detect genetically modified (GM) organisms. In the method, genomic DNA extracted from an agricultural product is analyzed using various qualitative real-time PCR assays on a 96-well PCR plate, targeting for individual GM events, recombinant DNA (r-DNA) segments, taxon-specific DNAs, and donor organisms of the respective r-DNAs. In this article, we report the single-laboratory validation of both DNA extraction methods and component ...

Tópico(s): Insect Resistance and Genetics

2012 - Oxford University Press | Journal of AOAC International

Artigo Revisado por pares

Kôsuke Nakamura, Hiroshi Akiyama, Yuki Takahashi, Tomoko Kobayashi, Akio Noguchi, Kiyomi Ohmori, Masaki Kasahara, Kazumi Kitta, Hiroyuki Nakazawa, Kazunari Kondo, Reiko Teshima,

Genetically modified (GM) papaya (Carica papaya L.) line 55-1 (55-1), which is resistant to papaya ringspot virus infection, has been marketed internationally. Many countries have mandatory labeling regulations for GM foods, and there is a need for specific methods for detecting 55-1. Here, an event- and construct-specific real-time polymerase chain reaction (PCR) method was developed for detecting 55-1 in papaya products. Quantitative detection was possible for fresh papaya fruit up to dilutions of ...

Tópico(s): Insect Resistance and Genetics

2012 - Elsevier BV | Food Chemistry

Artigo Revisado por pares

Kaoru Yamazaki, Naoyuki Niitsu, Kôsuke Nakamura, Manabu Kanno, Hirohiko Kono,

We investigated the reaction paths of Stone–Wales rearrangement (SWR), i.e., π/2 rotation of two carbon atoms with respect to the midpoint of the bond, in graphene and carbon nanotube quantum chemically. Our particular attention is focused on the roles of electronic excitations and conical intersections (CIs) in the reaction mechanism. We used pyrene as a model system. The reaction paths were determined by constructing potential energy surfaces at the MS-CASPT2//SA-CASSCF level of theory. We found ...

Tópico(s): Graphene research and applications

2012 - American Chemical Society | The Journal of Physical Chemistry A

Artigo Revisado por pares

Takashi Suzuki, Tetsuo Hashimoto, Yoshisada Yabu, Phelix A.O. Majiwa, Shigeru Ohshima, Mitsuko Suzuki, Shaohong Lu, Mariko Hato, Yasutoshi Kido, Kimitoshi Sakamoto, Kôsuke Nakamura, Kiyoshi Kita, Nobuo Ohta,

Abstract. To clarify evolution and phylogenetic relationships of trypanosome alternative oxidase (AOX) molecules, AOX genes (cDNAs) of the African trypanosomes, Trypanosoma congolense and Trypanosoma evansi , were cloned by PCR. Both AOXs possess conserved consensus motifs (‐E‐, ‐EXXH‐). The putative amino acid sequence of the AOX of T. evansi was exactly the same as that of T. brucei . A protein phylogeny of trypanosome AOXs revealed that three genetically and pathogenically distinct strains of T. congolense ...

Tópico(s): Studies on Chitinases and Chitosanases

2005 - Wiley | Journal of Eukaryotic Microbiology

Artigo Revisado por pares

Kôsuke Nakamura, Kimitoshi Sakamoto, Yasutoshi Kido, Yoko Fujimoto, Takashi Suzuki, Mitsuko Suzuki, Yoshisada Yabu, Nobuo Ohta, Akiko Tsuda, Misao Onuma, Kiyoshi Kita,

Based on amino acid sequence similarity and the ability to catalyze the four-electron reduction of oxygen to water using a quinol substrate, mitochondrial alternative oxidase (AOX) and plastid terminal oxidase (PTOX) appear to be two closely related members of the membrane-bound diiron carboxylate group of proteins. In the current studies, we took advantage of the high activity of Trypanosoma vivax AOX (TvAOX) to examine the importance of the conserved Glu and the Tyr residues around the predicted ...

Tópico(s): Biochemical and Molecular Research

2005 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo Acesso aberto Revisado por pares

Yumiko Katoh, Mitsuaki Fujimoto, Kôsuke Nakamura, Sachiye Inouye, Kazuma Sugahara, Hanae Izu, Akira Nakai,

Protein aggregates are oligomeric complexes of misfolded proteins, and serve as the seeds of inclusion bodies termed aggresomes in the cells. Heat shock proteins (Hsps) prevent misfolding and aggregate formation. Here, we found that only avian Hsp25 dominantly accumulated in the aggresomes induced by proteasome inhibition. Molecular cloning of chicken Hsp25 (cHsp25) revealed that it belongs to the Hsp30 family, which is a subfamily of the α‐crystallin/small Hsp gene family. Unexpectedly, overexpression ...

Tópico(s): Enzyme Structure and Function

2004 - Wiley | FEBS Letters

Artigo Acesso aberto Revisado por pares

Satoshi Kimura, Shinsaku Matsumoto, Nagisa Muto, Tomoko Yamanoi, Tatsuya Higashi, Kôsuke Nakamura, Mineo Miyazaki, Moritoki Egi,

Although chloride is one of the major electrolytes measured routinely in dairy practice, the amount of attention chloride receives in critically ill patients is limited. There are still a few studies reporting the incidence of derangements of chloride and its association with patients' outcomes. Accordingly, we conducted a retrospective study to assess the prevalence of abnormality of serum chloride level in postoperative patients in the intensive care unit on the early phase of surgery and its ...

Tópico(s): Electrolyte and hormonal disorders

2014 - BioMed Central | Journal of Intensive Care

Artigo Revisado por pares

Shunpei Hitosugi, Kei Ohkubo, Ryosuke Iizuka, Yuki Kawashima, Kôsuke Nakamura, Sota Sato, Hirohiko Kono, Shunichi Fukuzumi, Hiroyuki Isobe,

Photoinduced electron-transfer processes in a carbonaceous supramolecular combination of a tubular host and a C60 guest were investigated with time-resolved transient absorption spectra upon laser flash photolysis. Following the formation of triplet charge-separated species via electron transfer from the host to the guest, a rapid back electron transfer proceeded to afford triplet C60.

Tópico(s): Porphyrin and Phthalocyanine Chemistry

2014 - American Chemical Society | Organic Letters

Artigo Revisado por pares

Kôsuke Nakamura, Hiroshi Akiyama, Noriaki Kawano, Tomoko Kobayashi, Kayo Yoshimatsu, Junichi Mano, Kazumi Kitta, Kiyomi Ohmori, Akio Noguchi, Kazunari Kondo, Reiko Teshima,

Genetically modified (GM) rice (Oryza sativa) lines, such as insecticidal Kefeng and Kemingdao, have been developed and found unauthorised in processed rice products in many countries. Therefore, qualitative detection methods for the GM rice are required for the GM food regulation. A transgenic construct for expressing cowpea (Vigna unguiculata) trypsin inhibitor (CpTI) was detected in some imported processed rice products contaminated with Kemingdao. The 3' terminal sequence of the identified transgenic ...

Tópico(s): Transgenic Plants and Applications

2013 - Elsevier BV | Food Chemistry

Artigo Acesso aberto

Asahi Tomitaka, R. Matthew Ferguson, Amit P. Khandhar, Scott J. Kemp, Satoshi Ota, Kosuke Nakamura, Yasushi Takemura, Kannan M. Krishnan,

The magnetic response of magnetic particle imaging (MPI) tracers varies with the slew rate of the applied magnetic field, as well as with the tracer's average magnetic core size. Currently, 25 kHz and 20 mT/μ0 drive fields are common in MPI, but lower field amplitudes may be necessary for patient safety in future designs. We studied how several different sizes of monodisperse MPI tracers behaved under different drive field amplitude and frequency, using magnetic particle spectrometry and ac hysteresis ...

Tópico(s): Minerals Flotation and Separation Techniques

2015 - IEEE Magnetics Society | IEEE Transactions on Magnetics

Artigo Revisado por pares

Shinichi Sato, Kôsuke Nakamura, Hiroyuki Nakamura,

Tyrosine-specific chemical modification was achieved using in situ hemin-activated luminol derivatives. Tyrosine residues in peptide and protein were modified effectively with N-methylated luminol derivatives under oxidative conditions in the presence of hemin and H2O2. Both single and double modifications of the tyrosine residue occurred in the reaction of angiotensin II with N-methylated luminol derivative 9. Tyrosine-specific chemical modification of the model protein bovine serum albumin (BSA) ...

Tópico(s): Fluorine in Organic Chemistry

2015 - American Chemical Society | ACS Chemical Biology

Artigo Acesso aberto Revisado por pares

Hiroyuki Isobe, Kôsuke Nakamura, Shunpei Hitosugi, Sota Sato, Hiroaki Tokoyama, Hideo Yamakado, Koichi Ohno, Hirohiko Kono,

The dynamics of a carbonaceous molecular bearing were investigated by DFT methods to reveal dual-mode motions with a minute energy barrier.

Tópico(s): Nonlinear Optical Materials Research

2015 - Royal Society of Chemistry | Chemical Science

Carta Acesso aberto Revisado por pares

Hiroyuki Isobe, Kôsuke Nakamura, Shunpei Hitosugi, Sota Sato, Hiroaki Tokoyama, Hideo Yamakado, Koichi Ohno, Hirohiko Kono,

We reply to the comments raised by Cabaleiro-Lago et al. on our article (H. Isobe et al. , Chem. Sci. , 2015, 6 , 2746–2753).

Tópico(s): Advanced Chemical Physics Studies

2016 - Royal Society of Chemistry | Chemical Science