Produção Nacional
Revisado por pares
Rogério Favareto, Pedro. H. Fregadolli, Vladimir Ferreira Cabral, O. A. C. Antunes, Lúcio Cardozo‐Filho,
Vapor–liquid equilibrium (VLE) of acrylonitrile and the solubility of p-bromobenzaldehyde in compressed and/or supercritical carbon dioxide were measured using a synthetic static method with a variable-volume cell with a front sapphire window for visualization of phase transitions. For CO2 + acrylonitrile, the bubble point (BP) and dew point (DP) were verified at temperatures ranging from (303 to 333) K and pressure up to 100 bar. For CO2 + p-bromobenzaldehyde, solid−fluid (SF) transitions were verified ...
Tópico(s): Ionic liquids properties and applications
2008 - American Chemical Society | Journal of Chemical & Engineering Data
Helena Branco, Júlio Oliveira, Catarina Antunes, Lúcio Lara Santos, M. Helena Vasconcelos, Cristina P. R. Xavier,
Pirfenidone, an antifibrotic drug, has antitumor potential against different types of cancers. Our work explored whether pirfenidone sensitizes non-small cell lung cancer (NSCLC) cell lines to chemotherapeutic treatments. The cytotoxic effect of paclitaxel in combination with pirfenidone against three NSCLC cell lines (A549, NCI-H322 and NCI-H460) was evaluated using the sulforhodamine B assay. The effects of this combination on cell viability (trypan blue exclusion assay), proliferation (BrdU incorporation ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
Andrea de Martino Luppi, Guilherme Emílio Ferreira, Denis Luiz Prudêncio, Douglas Eulálio Antunes, Lúcio Araújo, Diogo Fernandes dos Santos, Marcello Henrique Nogueira‐Barbosa, Isabela Maria Bernardes Goulart,
Leprosy household contacts (HC) represent a high-risk group for the development of the disease. Anti-PGL-I IgM seropositivity also increases the risk of illness. Despite significant advances in leprosy control, it remains a public health problem; and early diagnosis of this peripheral neuropathy represents one of the main goals of leprosy programs. The present study was performed to identify neural impairment in leprosy HC by analyzing differences in high-resolution ultrasonographic (US) measurements ...
Tópico(s): Ocular Diseases and Behçet’s Syndrome
2023 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Vanessa Amaral Mendonça, Rosane Dias Costa, Gustavo Eustáquio Brito Alvim de Melo, Carlos Maurício de Figueiredo Antunes, Antônio Lúcio Teixeira,
A hanseníase é doença crônica infecciosa que se caracteriza por apresentar formas clínicas contrastantes, que são dependentes da interação do bacilo com a resposta imune do hospedeiro. O estudo dos processos imunológicos torna-se fundamental para o entendimento dos mecanismos envolvidos na apresentação e no desenvolvimento da doença. Neste artigo, é revisada a imunopatogênese da hanseníase.
Tópico(s): Infectious Diseases and Tuberculosis
2008 - Elsevier BV | Anais Brasileiros de Dermatologia
Produção Nacional
Revisado por pares
Götz Schroth, Deborah Faria, Marcelo Antunes Araújo, Lúcio Cadaval Bedê, Sunshine A. Van Bael, Camila Righetto Cassano, Leonardo de Carvalho Oliveira, Jacques Hubert Charles Delabie,
Tópico(s): Oil Palm Production and Sustainability
2011 - Springer Science+Business Media | Biodiversity and Conservation
Produção Nacional
Revisado por pares
Pietro Menezes Sanchez Macedo, Paulo Tarso Sanches de Oliveira, Mauro Antônio Homem Antunes, Valdemir Lúcio Durigon, E. C. C. Fidalgo, Daniel Fonseca de Carvalho,
We present a new approach for calculating the C-factor of RUSLE considering the effect of low-reflectance vegetation cover areas on the reduction of the effects on erosion caused by rainfall seasonality. For this, we propose the coefficients Cr2 (rescaled 2) and C-PC (Precipitation Correction), which represent the C-factor, and an adaptation in NDVI calculation, according to the seasonality of precipitation (NDVI-PC). The Cr2 factor is used when there is no seasonal effect of rainfall on vegetation, ...
Tópico(s): Remote Sensing and LiDAR Applications
2020 - Elsevier BV | International Soil and Water Conservation Research
Produção Nacional
Revisado por pares
Gaya C.S. Vieira, Henrique dos Santos Antunes, Alejandro R. Pérez, Lúcio Souza Gonçalves, Fernanda E. Antunes, José F. Siqueira, Isabela N. Rôças,
In this case series, bacterial reduction promoted by antimicrobial photodynamic therapy (PDT) used during endodontic surgery was evaluated. Cases were also followed up, and the surgical outcome was reported. The study consisted of 19 teeth with posttreatment apical periodontitis that were consecutively treated by endodontic surgery. After apicoectomy, the root end was treated with PDT using methylene blue as the photosensitizer. Bacteriologic samples were taken from both the cut root surface and ...
Tópico(s): Ocular Infections and Treatments
2018 - Elsevier BV | Journal of Endodontics
Produção Nacional
Revisado por pares
Cosmo Rossi, Christian Gonçalves Alonso, Octávio Augusto Ceva Antunes, Reginaldo Guirardello, Lúcio Cardozo‐Filho,
In the past few years there has been a growing interest in environmentally clean renewable sources for hydrogen production. In this context new technologies have been developed for ethanol and glycerine reforming. Hydrogen production varies significantly according to the operating conditions such as pressure, temperature and feed reactants ratio. The thermodynamic analysis provides important knowledge about the effects of those variables on the process of ethanol and glycerine reforming. The present ...
Tópico(s): Catalysis and Oxidation Reactions
2008 - Elsevier BV | International Journal of Hydrogen Energy
Produção Nacional
Daniell Rodrigo Rodrigues Fernandes, Nicanor Tiago Bueno Antunes, Elton Lucio Araújo, Rogéria Inês Rosa Lara, Nelson Wanderley Perioto,
The objectives of this study were to carry out a survey of families of Hymenoptera, with emphasis on Ichneumonidae, in an area of Caatinga, and register the occurrence of new species, if any, for the biome. Samples were taken with Malaise traps between September and November 2008 in a native area of vegetation of Serra do Lima, municipality of Patu, Rio Grande do Norte, Brazil. 7,562 hymenopterans, from 11 superfamilies and 31 families, were collected. The most abundant superfamilies were: Chalcidoidea ( ...
Tópico(s): Insect-Plant Interactions and Control
2020 - Entomologistas do Brasil | EntomoBrasilis
Produção Nacional
Revisado por pares
Ana Isabel Vieira Fernandes, Ciro Leite Mendes, Raíssa Holmes Simões, Ana Elisa Vieira Fernandes Silva, Clarissa Barros Madruga, Carlos Alexandre Antunes de Brito, Lúcio Roberto Cançado Castellano, Marli Tenório Cordeiro,
A 26-year-old postpartum female presented with symptoms characteristic of dengue fever on the 16th day of puerperium. On the third day of the illness, the patient presented a clinical picture consistent with shock. Tests determined primary infection with dengue virus serotype 2. Cardiac tamponade was confirmed by echocardiography. This rare manifestation is described in a patient without any associated comorbidity.
Tópico(s): Cardiovascular Effects of Exercise
2017 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Fernanda Santos, Auteliano Antunes dos Santos, F. Bruni, Lúcio T. Santos,
Railroad wheels fail in two main modes: rolling surface defects like spalling, shelling and wear, and internal defects including cracks propagating after a change takes place in the original stress pattern. Although the effects of the latter are almost always catastrophic, the former is more usual. The onset of rolling surface defects depends on the strength of the surface and the applied loads. The strength is related to surface hardness and can be determined through experimental evaluation under ...
Tópico(s): Gear and Bearing Dynamics Analysis
2004 - Springer Science+Business Media | Journal of the Brazilian Society of Mechanical Sciences and Engineering
Micaela Freitas, Fábio Miguel Ferreira, Sónia Carvalho, Fernanda Silva, Paula Lopes, Luís Antunes, Sofia Salta, Francisca Diniz, Lúcio Lara Santos, José Flávio Videira, Rui Henrique, Cármen Jerónimo,
Colorectal cancer (CRC) is one of the most incident cancers, associated with significant morbidity and mortality, and usually classified into three main molecular pathways: chromosomal instability, microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Currently, available screening methods are either costly or of limited specificity, impairing global implementation. More cost-effective strategies, including DNA methylation-based tests, might prove advantageous. Although some ...
Tópico(s): Colorectal Cancer Screening and Detection
2018 - BioMed Central | Journal of Translational Medicine
Produção Nacional
Revisado por pares
Cléver Briedis, João Carlos de Moraes Sá, Roberto Simão De-Carli, Erielton Aparecido Pupo Antunes, Lucas Simon, Marielle Leticia Romko, Lucio Schenekenberg Elias, Ademir de Oliveira Ferreira,
In soils under no-tillage (NT), the continuous crop residue input to the surface layer leads to carbon (C) accumulation. This study evaluated a soil under NT in Ponta Grossa (State of Paraná, Brazil) for: 1) the decomposition of black oat (Avena strigosa Schreb.) residues, 2) relation of the biomass decomposition effect with the soil organic carbon (SOC) content, the particulate organic carbon (POC) content, and the soil carbon stratification ratio (SR) of an Inceptisol. The assessments were based on seven ...
Tópico(s): Crop Yield and Soil Fertility
2012 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo
Produção Nacional
Revisado por pares
Vanessa Amaral Mendonça, Gustavo Eustáquio Brito Alvim de Melo, Mauro Martins Teixeira, Olindo Assis Martins‐Filho, Carlos Maurício de Figueiredo Antunes, Antônio Lúcio Teixeira,
Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes.
Tópico(s): Chronic Lymphocytic Leukemia Research
2008 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
This paper discusses some results of a broader research, focusing on a set of eleven socio-educational practices aiming to overcome school failure and dropout, developed in Portugal, giving particular attention to the local and innovative dimensions. This research aims to understand the point of view of the several actors involved, about which factors, processes and relationships contribute the most to building such practices. Data was gathered through documental analysis and semi-structured interviews ...
Tópico(s): Global Educational Policies and Reforms
2019 - Hipatia Press | Multidisciplinary Journal of Educational Research
Produção Nacional
Revisado por pares
Alyssa Teixeira Obeid, Luisa Helena Antunes Garcia, Tatiana Rita de Lima Nascimento, Lúcio Roberto Cançado Castellano, Juliana Fraga Soares Bombonatti, Heitor Marques Honório, Rafael Francisco Lia Mondelli, Salvatore Sauro, Marilia Mattar de Amoêdo Campos Velo,
This in vitro study aimed to evaluate the overall mechanical properties of resin infiltrants doped with bioactive nanofibers and their ability in inhibiting enamel demineralization or achieving remineralization of the adjacent enamel to white spots. A commercial resin infiltrant (ICON, DMG) was doped with hybrid inorganic-organic nanofibers and analyzed for degree of conversion (DC, n = 3) and surface hardness (SH, n = 6). Subsequently, enamel specimens (6 × 4 × 2 mm3) were prepared and submitted to a demineralizing/ ...
Tópico(s): Dental Implant Techniques and Outcomes
2022 - Elsevier BV | Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
Produção Nacional
Revisado por pares
Vanessa Amaral Mendonça, Luiz Cosme Cotta Malaquias, Gustavo Eustáquio Brito Alvim de Melo, Alexandre Castelo-Branco, Carlos Maurício de Figueiredo Antunes, Antônio Luiz Pinho Ribeiro, Mauro Martins Teixeira, Antônio Lúcio Teixeira,
Diagnosis of leprosy is usually made clinically and there are no tests available for the routine laboratory diagnosis of the disease. The aim of this study was to investigate the potential role of chemokines as biologic markers of disease activity. We used an enzyme-linked immunosorbent assay to measure chemokines in plasma of patients with leprosy (LE) and non-infected (NI) individuals. There were significantly greater concentrations of the chemokines CCL3 and CCL11 in plasma of LE patients than ...
Tópico(s): Infectious Diseases and Tuberculosis
2007 - American Society of Tropical Medicine and Hygiene | American Journal of Tropical Medicine and Hygiene
Produção Nacional
Revisado por pares
Daniel Fonseca de Carvalho, Valdemir Lúcio Durigon, Mauro Antônio Homem Antunes, Wilk Sampaio de Almeida, Paulo Tarso Sanches de Oliveira,
The objective of this work was to evaluate the seasonal variation of soil cover and rainfall erosivity, and their influences on the revised universal soil loss equation (Rusle), in order to estimate watershed soil losses in a temporal scale. Twenty-two TM Landsat 5 images from 1986 to 2009 were used to estimate soil use and management factor (C factor). A corresponding rainfall erosivity factor (R factor) was considered for each image, and the other factors were obtained using the standard Rusle method. ...
Tópico(s): Hydrology and Sediment Transport Processes
2014 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira
Leila R. Martins, Paulo Lúcio, Alice Melão, Inês Antunes, Bruno A. Cardoso, Ryan Stansfield, Maria Teresa Sabrina Bertilaccio, Paolo Ghia, Denis Drygin, María Gomes da Silva, João T. Barata,
Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia
Tópico(s): Immunodeficiency and Autoimmune Disorders
2013 - Springer Nature | Leukemia
Produção Nacional
Revisado por pares
Carolina Coimbra Marinho, Thales Lage Bicalho Bretas, Izabela Voieta, Leonardo Campos de Queiróz, Raiza Ruiz‐Guevara, Antônio Lúcio Teixeira, Carlos M. F. Antunes, Áluízio Prata, José Roberto Lambertucci,
Non-invasive markers of fibrosis have been used to diagnose liver fibrosis in a variety of diseases. Hyaluronic acid (HA) and collagen IV (C-IV) levels were measured in the sera of patients from an endemic area for schistosomiasis in Brazil to diagnose and to rank the intensity of liver fibrosis. Seventy-nine adult patients with schistosomiasis, in the age range of 21-82 years (49 ± 13.4) were submitted to clinical and ultrasonographic examinations. Ultrasound was employed to diagnose and categorise ...
Tópico(s): Parasites and Host Interactions
2010 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz
Produção Nacional
Revisado por pares
Maíra da Costa, Rafael Cardoso Seiceira, Carlos Rangel Rodrigues, Cristiane Rodrigues Drago Hoffmeister, Lúcio Mendes Cabral, Helvécio Vinícius Antunes Rocha,
AIDS constitutes one of the most serious infectious diseases, representing a major public health priority. Efavirenz (EFV), one of the most widely used drugs for this pathology, belongs to the Class II of the Biopharmaceutics Classification System for drugs with very poor water solubility. To improve EFV’s dissolution profile, changes can be made to the physical properties of the drug that do not lead to any accompanying molecular modifications. Therefore, the study objective was to develop and characterize ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2012 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Produção Nacional
Revisado por pares
Matías Bonansea, Claudia Ledesma, Claudia Rodríguez, Lucio Pinotti, Mauro Antônio Homem Antunes,
Empirical relationships between Landsat data and water clarity expressed in terms of Secchi disk transparency (SDT) have been widely used for monitoring and assessment of water quality. The atmosphere affects differently sensor bands depending on the waveband, thus affecting the relationships obtained from top-of-atmosphere reflectance. The objective of this study was to evaluate whether the reliability of water clarity can be improved applying atmospheric correction of Landsat imagery. Further, ...
Tópico(s): Marine and coastal ecosystems
2015 - Elsevier BV | Advances in Space Research
Produção Nacional
Revisado por pares
Vanessa Amaral Mendonça, Rosane Dias Costa, Sandra Lyon, Rachel Adriana Penido, Valdinéria Oliveira Borges, Thales Lage Bicalho Bretas, Carlos Maurício de Figueiredo Antunes, Mauro Martins Teixeira, Antônio Lúcio Teixeira,
Leprosy, whose etiologic agent is Mycobacterium leprae, is an illness of ample clinical and immunopathological spectrum. Although chemokines seem to be involved in the immunopathogenesis of leprosis, few studies have been carried out to unveil the potential of chemokines as biological markers of the disease. The purpose of this study was to investigate the value of measuring CCL2, CCL3, CCL11 and CCL24 in plasma of patients with leprosy (LE) at different stages of multi-drug therapy (MDT). Chemokines ...
Tópico(s): Ocular Diseases and Behçet’s Syndrome
2009 - Elsevier BV | Acta Tropica
Produção Nacional
Revisado por pares
Eduardo Costa Pinto, Flávia Almada do Carmo, Thiago da Silva Honório, Rita de Cássia da Silva Ascenção Barros, Helena Carla Castro, Carlos Rangel Rodrigues, Valéria Sant'Anna Dantas Esteves, Helvécio Vinícius Antunes Rocha, Valéria Pereira de Sousa, Lúcio Mendes Cabral,
The purpose of this study was to propose an analytical procedure that provides the effects of particle size and surface area on dissolution of efavirenz. Five different batches obtained by different micronization processes and with different particle size distribution and surface area were studied. The preformulation studies and dissolution curves were used to confirm the particle size distribution effect on drug solubility. No polymorphic variety or amorphization was observed in the tested batches ...
Tópico(s): Analytical Chemistry and Chromatography
2012 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
Luís Antunes, Lúcio Lara Santos, María José Bento,
The aim of this study was to evaluate net survival from cancer diagnosed during the period 2001–2010 in the north region of Portugal to identify the tumours that need actions to improve the outcomes. Data were retrieved from the North Region Cancer Registry of Portugal database. The top 20 cancer sites in adults were considered: oesophagus, stomach, colon, rectum, pancreas, liver, larynx, lung, skin melanoma, breast, cervix, corpus uteri, ovary, prostate, kidney, bladder, brain and central nervous ...
Tópico(s): Colorectal Cancer Screening and Detection
2017 - Lippincott Williams & Wilkins | European Journal of Cancer Prevention
Produção Nacional
Revisado por pares
Bruno Raphael de Carvalho Santos, Luana Bittencourt Saraiva, Claudete Barbosa Ruschival, Alef Vernon de Oliveira Santos, Eduardo Jorge Lira Antunes da Silva, Lúcio Vasconcellos Dias, Nelson Kuwahara,
Este artigo apresenta o conceito de um aplicativo em realidade aumentada para dispositivo móvel, desenvolvido com o objetivo de apoiar a realização de atividades físicas. O que se pretende é estimular a realização de exercícios físicos para melhoria da qualidade de vida e diminuição do sedentarismo entre a população ativa, prevenindo o aparecimento de doenças não contagiosas. O processo de desenvolvimento está no uso de métodos e ferramentas de UX e UI Design. As etapas de Imersão, Definição, Ideação ...
Tópico(s): Usability and User Interface Design
2021 - | DAT Journal
Produção Nacional
Revisado por pares
Marcos C. Álvarez, Maria Luiza L. Albuquerque, Henrique P. Neiva, Luís Cid, Diogo Teixeira, Rui Matos, Raúl Antunes, Liane Lúcio, Leandro de Oliveira Sant’Ana, Diogo Monteiro,
Background and Objectives: Fibromyalgia are heterogeneous and differ from patient to patient; however, the most reported are general myalgia and at specific points associated with fatigue and certain psychological adversities. Physical activity can mitigate the effects of the symptoms. However, the associations between fibromyalgia-related fatigue, self-esteem, anxiety, depression, satisfaction with life and physical activity are unclear. Therefore, the aim of the present study was to understand ...
Tópico(s): Health and Wellbeing Research
2022 - Multidisciplinary Digital Publishing Institute | Medicina
Produção Nacional
Revisado por pares
Anderson Felipe Jácome de França, Jonalson Nogueira de Araujo, Elizeu Antunes dos Santos, Gabriella Silva Campos Carelli, D.A. Silva, Ticiana Maria Lúcio de Amorim, Ludovico Migliolo, Elizeu Antunes dos Santos, Adeliana S. Oliveira, Adriana Ferreira Uchôa,
Vicilins are seed proteins, and they constitute 70–80% of the total protein in leguminous seeds; with amolecular mass between 150 and 190 kDa, they are composed of subunits without disulfide bridges, with high affinity for chitin-binding. They are also associated with seed defense against insect pests. The chitin-binding vicilin from Anadenanthera colubrina seeds was purified by ammonium sulfate, followed by affinity chromatography on a chitin column, molecular exclusion on Superdex 75 Tricorn in ...
Tópico(s): Agricultural pest management studies
2021 - Elsevier BV | Saudi Journal of Biological Sciences
Produção Nacional
Revisado por pares
Mara Heloisa Neves Olsen, Gisele Cantalice Salomão, V. Drago, Christiane Fernandes, Adolfo Horn, Lúcio Cardozo‐Filho, O. A. C. Antunes,
The catalytic activities of 5,10,15,20-meso-tetraphenylporphyrinatechloroiron(III), [Fe(TPP)Cl], and 5,10,15,20-meso-tetraphenylporphyrinatechloroiron(III) encapsulated in zeolite Y, [FeIII(TPP)Y], were investigated using cyclohexane as substrate in supercritical carbon dioxide (scCO2), using either tert-butyl-hydroperoxide (t-BuOOH) or hydrogen peroxide (H2O2) as terminal oxidants. Using [Fe(TPP)Cl], in 2 h, at 0.724 g cm−3, were obtained conversions of up to 26 turnover per hour. The selectivity with [ ...
Tópico(s): Metal-Catalyzed Oxygenation Mechanisms
2005 - Elsevier BV | The Journal of Supercritical Fluids
Produção Nacional
Revisado por pares
Marcos L. Corazza, Lúcio Cardozo‐Filho, O. A. C. Antunes, Cláudio Dariva,
The use of supercritical CO2 (SCCO2) as an alternative solvent in reactional systems has received increased attention nowadays because of its favorable transport properties that can accelerate mass-transfer limited reactions and also because of imposed environmental restrictions. The comprehension of the phase behavior of the reaction mixture is of relevance to determine selectivity and yield of such reactions at high pressures. In this context, the main objective of this work was to investigate ...
Tópico(s): Subcritical and Supercritical Water Processes
2003 - American Chemical Society | Journal of Chemical & Engineering Data