P B, Edna Davies, Martina Thomas, John Dugdale, Michael Prescott, Julia Llewellyn Smith, Mark Stretton, Matthew Wall, Karan Junker, Barbara Hall, Nigel Botherway, Alec Stewart, Jeff Dawson, Peter Shaffer, N J, Fred Redwood, Christine McGourty, John Seddon, Stewart McArthur, Nicholas Rufford, Anthony Clare, Rob Hughes, John Peter, Amanda Ursell, Jonathan Miller, Jim Howard, Emer Gillespie's, Colm Murphy, J D, Mark Hiscox, Tim Nagle, Ivo Tennant, Terence Blacker, Elizabeth Forrest, Alistair Scott, Kathryn Cooper, Hannah Morris, Sally Payne, Brian Clement, David Smith, Kirstie Hamilton City Editor, Alastair McCall, Tim Richards, Ian J Hartill, Melanie Phillips, Neil Wormald, E P, George Harrison, Andrew Sullivan, Polly Vernon, Richard McCann, Mary Wilson, Lynne Truss, Dr Roger Headerson, Dr Roger Henderson, Leslie Fraser-Mitchell, A C, Tony Allen-Mills, Simon Wilde, Martin James, Robert Sandall, Isabella Blow, Anthony Sattin, Alison Brace, Robert Winnett, Irwin Stelzer, Jane Moore, Nick Proctor, Anthony Seldon, Peter Wilson, Robert Hewison, M Rayers, Mr G Lazarus, Lawrence Dallaglio, David Dougill, Sir Alan Sugar, John Evans, Philip Kingsley, Tony Edwards, H C, Marian Martin, Sarah Toyne, David Hewson, Jonathon Carr-Brown, Alasdair Reid, Margarette Driscoll, Jeremy Clarkson, Stewart Lee, Peter Conradi, Christine Stopp, Louise Taylor, John Waples Deputy City Editor, Dr Kirkby Howard, Eben Black, Anita Chaudhuri, Liz Jones, Lisa Chaney, Ewan McAlpine, David Eimer, Andrew Barr, Phil Craigie, Belinda Bugkley, Adam Nathan, Denis Christian, Nick Gardner, Jane O'grady, Mr Mills, Richard Johnson, L Rayers, Alison Riddell, S Labovitch, Stuart Wavell, Roger Eglin, Paul Donovan, Deborah Collcutt, Alastair Hendy, Fabienne Smith, Peter Bishop, Lucinda Kemeny, Smita Talati, Jasper Gerard, Paul Bray, Paul Driver, Boris Schapiro, John Humphrys, Nicholas Hellen, Richard Brooks, Ian Hawkey, Pete Sawyer, Shelley Von Strunckel, Christopher Morgan, David Leppard, Sian Philips, Paul Durman, Marc Hinton, Matt Seaton, Mark Edwards, Kirstie Hamilton, Robbie Paul, Sarah Gracie, David Rothnie, Susan Clark, Nigel Batherway, David Lawrenson, Eben Black Chief Political Correspondent, Hugh McLlvanney, Samantha Fisher, Peter McCann, George Sassoon, Rob Brydon, Michael Fell, Charlotte Wolf, Victoria O'Brien, Alan Combes, Peter Hale, Sean Newsom, Sue Reid, C L, Raymond Keene, Gareth Huw Davies, Senay Boztas, Cosmo Landesman, Peter Hall, Marie Colvin, Terry Waite, Diana Wright, Greg Hadfield, Robbie Hudson, Andy Knott, Cliff Lambton, Chris Partridge, Michael Prescott Political Editor, Stephen Jones, Richard Evans, Tim Moorey, M J, Stephen Roberts, Dominic Rushe, Caroline Donald, Lois Rogers Medical correspondent, Keith Wheatley, Claire Oldfield, David Walsh, Jo Glanville-Blackburn, Steve Fitzgerald, Trevor Lewis, S P, Bryan Appleyard, Paul Britton, Danny O'brien, Stephen Armstrong, John Elliott, Ron Clarke, Nick MacKinnon, Paul Kavanagh, Ann Cloag, Simon Verdon, Peter Thomas Lovesey, Mark Prigg, Mark O'Shea, Nick Nalladorai, Roland White, Garth Alexander, Heather McCabe, Matthew Chapman, Steve Yorke, Robert Shepherd, Maurice Chittenden, Alex Fortune, Kevin Pratt, Richard Brooks Arts Editor, Roger Lewis, Molly Hammond, Richard Rae, Mark Franchetti, Jonathan Powell, John Graham, Martin Ivens, Ray Hutton, Michael Sheridan, D J Taylor, Christine Webb, John Harlow, Philip Beresford, Martin Pollecoff, Donald McRae, Godfrey Smith, Paul Metson, Barry Collins, John Waples, Toby Musgrave, Hunter Davies, Matthew Campbell, Brian Glanville, Ghulan Hasnain, Tom Robbins, Andrew Lycett, Nick Fielding, David Snowden, Lewis Stuart, Jonathan Carr-Brown, Stephen Pettitt, Jonathan Leake Science Editor, John Spurling, T L, R H, Angie Buttrose, Sally Kinnes, Liam Clarke, Nicholas Hellen Media Editor, David Wickers, Roger Dobson, Tom Rhodes, John R Mickerson, Suzy Greaves, John Aizlewood, J P, Mark Hodson, Graham Norwood, Joe Lovejoy, Rupert Steiner, Helen, Hugh Pearman, Dan Cairns, T R Speight, David Parsley, Tony Perrottet, Christopher Bray, Tim Rice, George Noble, David Smith Economics Editor, Tom Deveson, Christian Dymond, Penny Perrick, Ms S Fleming, S Batestone, Walter Ellis, India Knight, Steve Grant, Simon Howard, Patrick McIlroy, Danny Danziger, Barry Newcombe, Rosie Waterhouse, Max Green, Sian Griffiths, Nicola Gill,
... s Bazaar Movie Market Bernaco Marketing Ltd Compuserve Laetitia Allen The Sunday Times The Iron Bed Company ...
2000 - Gale Group | Sunday Times HA GDA
Aurélie Allais‐Bonnet, Cécile Grohs, Ivica Međugorac, Stefan Krebs, Anis Djari, Alexander Graf, Sébastien Fritz, Doris Seichter, Aurélia Baur, Ingolf Ruß, Stéphan Bouet, Sophie Rothammer, Per Wahlberg, Diane Esquerré, Chris Hozé, Mekki Boussaha, Bernard Weiss, Dominique Thépot, Marie-Noëlle Fouilloux, Marie‐Noëlle Rossignol, E. van Marle-Köster, Gunnfríður Elín Hreiðarsdóttir, Sarah Barbey, Dominique Dozias, Emilie Cobo, Patrick Reversé, Olivier Catros, J Marchand, Pascal Soulas, Pierre Van Roy, B. Marquant-Leguienne, Daniel Le Bourhis, Laëtitia Clément, Laura Salas‐Cortés, Eric Venot, Maëlle Pannetier, Florence Phocas, Christophe Klopp, Dominique Rocha, Michel Fouchet, L. Journaux, Carine Bernard-Capel, Claire Ponsart, Andre A. Eggen, Helmut Blum, Yves Gallard, Didier Boichard, Éric Pailhoux, Aurélien Capitan,
Despite massive research efforts, the molecular etiology of bovine polledness and the developmental pathways involved in horn ontogenesis are still poorly understood. In a recent article, we provided evidence for the existence of at least two different alleles at the Polled locus and identified candidate mutations for each of them. None of these mutations was located in known coding or regulatory regions, thus adding to the complexity of understanding the molecular basis of polledness. We confirm ...
Tópico(s): Cancer-related molecular mechanisms research
2013 - Public Library of Science | PLoS ONE
Richard Glauser, Weekend Money Staff, Anthony Harris, Hans Albert, Paul Heiney, Clifford Longley, Le Gallois, Michael Saward, Patricia Davies, Louise Roddon, Robert W. Lamb, Richard Warren, Jane MacQuitty, Simon Barnes, Richard Ford, Home Correspondent, Daniel Schulthess, Ruth Barcan Marcus, Jill Sherman Political Correspondent, Bill Frost, Andrew Longmore, Tim Judah, Wolfgang Röd, Sheila Gunn, Political Correspondent, Martin Spence, Harvey Elliott, Edmund Runggaldier, Shirley Jenkins, Ivo Tennant, Angela MacKay, Ross Tieman, Industrial Correspondent, Philip Howard, Massimo Mugnai, Ian Murray, Guislaine Morland, A. N. Gudgin, Brian Fender, Melinda Wittstock, Media Correspondent, Daniel Adams, Noel Goodwin, David Armstrong, Peter B. Landon, Carol Leonard, Lynne Truss, Frances Welch, Albert Dormer, Harry Eyres, Richard Eaton, Stuart Jones Football Correspondent, Neil Bennett, Banking Correspondent, Aurea Carpenter, J. H., Tom Walker, B. Xiros, Colin Narbrough, Jean Wilson, Antony Flew, Kevin Mulligan, Joe Joseph, Francesca Greenoak, Ruth Gledhill, Religion Correspondent, Mitchell Platts, Golf Correspondent, Stuart Jones, Peter Ball, Ruth Gledhill, Sheila Gunn and Jill Sherman, Barry Smith (Editor), Michael Hofmann, Peter Ackroyd, Peter Bills, Michael Evans, Defence Correspondent, Jeremy Laurance Health Services Correspondent, Chris Smart, Alan Hamilton, Robin Young, Joy Hancox, John Byron, Rodney Milnes, Robert Nye, Daniel Johnson, Jenny MacArthur, H. Lindsay, Michael Clark, Leslie Geddes-Brown, Michael Hamlyn, Douglas Broom, Local Government Correspondent, Frances Bissell, Ian Bradley, Charles Bremner, Neil Bennett Banking Correspondent, Peter Barnard, Ros Drinkwater, L. T., Julie Welch, D. M. Silver, Keith Campbell, Angela Brooks, Nicole Swengley, John Woodcock, George Brock, Robert McGeehan, Lindsay Cook Money Editor, David Miller, Rupert Bruce, Jill Insley, Geoffrey Wheeler, Alison Roberts, Karl Schuhmann, Richard Hough, Michael Watkins, David Powell Athletics Correspondent, Kerry Gill, Raymond Keene, Paul Du Vivier, Raymond Keene, Chess Correspondent, Frances Gibb, Legal Correspondent, Paul Wilkinson, Nick Nuttall and Nigel Hawkes, Alix Ramsay, Matthew d'Ancona, Richard Evans, Leo Chamberlain, Craig Seton, Ian Ross, Mike McShane, Brian Beel, Keith MacKlin, Rudolf Haller, Jamie Dettmer, Peter Simons, Joanna Pitman, Nick Nuttall, Technology Correspondent, Sara McConnell, Christopher Walker, P. H., Michael Clark and Rodney Hobson, Colin Narbrough, Economics Correspondent, Brian Alderson, Clive White, Liz Smith, Willard Van Orman Quine, John Shaw, L. E. Dowdall, Jane Owen, Edna St Vincent Millay, Ben MacIntyre, Peter Victor, Marlene Dietrich, Alan Lee Cricket Correspondent, Michael Phillips, Lindsay Cook Weekend Money Editor, Martin Waller, Charles Hennessy, Dallas Willard, Mark Sanderson, Renéthom, Cyrus Bradford, Benedict Nightingale, Jonathan Meades, Dennis Stevenson, Richard M. Norman, David Powell, Jack Bailey, Sam Kiley, Arthur Leathley, Valerie Grove, Michael Evans, Laetitia Chalk, Jay McInerney, Alan Jackson, Adam Kelliher, Lorenzo Pena, Matthew Bond, Jan Wolenski, John O'leary, Education Correspondent, Judy Froshaug, Philip Jacobson, Andrew Longmore, Tennis Correspondent, Robert P. Lamb (Executive Producer), Stewart Tendler and Jill Sherman, John Watson,
... Frisco Paring the meal to fit Gut Feelings Clement Freud Clement Freud cooks a dish for Mike McShane Pears ...
1992 - Gale Group | TDA
Aurélien Capitan, Aurélie Allais‐Bonnet, Alain Pinton, B. Marquant-Le Guienne, Daniel Le Bourhis, Cécile Grohs, Stéphan Bouet, Laëtitia Clément, Laura Salas‐Cortés, Eric Venot, Stéphane Chaffaux, Bernard Weiss, Arnaud Delpeuch, Guy Noé, Marie‐Noëlle Rossignol, Sarah Barbey, Dominique Dozias, Emilie Cobo, Harmonie Barasc, Aurélie Auguste, Maëlle Pannetier, Marie-Christine Deloche, Emeline Lhuilier, Olivier Bouchez, Diane Esquerré, Gérald Salin, Christophe Klopp, Cécile Donnadieu, Céline Chantry-Darmon, Hélène Hayes, Yves Gallard, Claire Ponsart, Didier Boichard, Éric Pailhoux,
Polled and Multisystemic Syndrome (PMS) is a novel developmental disorder occurring in the progeny of a single bull. Its clinical spectrum includes polledness (complete agenesis of horns), facial dysmorphism, growth delay, chronic diarrhea, premature ovarian failure, and variable neurological and cardiac anomalies. PMS is also characterized by a deviation of the sex-ratio, suggesting male lethality during pregnancy. Using Mendelian error mapping and whole-genome sequencing, we identified a 3.7 Mb ...
Tópico(s): Wheat and Barley Genetics and Pathology
2012 - Public Library of Science | PLoS ONE
Fabienne Nuttinck, Laurence Gall Pouget Gall, Sylvie Ruffini, Ludivine Laffont, Laëtitia Clément, Pierrette P. Reinaud, Pierre Adenot, Bénédicte Grimard, Gilles Charpigny, Brigitte Marquant-Le Guienne,
During the periovulatory period, the induction of prostaglandin G/H synthase-2 (PTGS2) expression in cumulus cells and associated prostaglandin E2 (PGE2) production are implicated in the terminal differentiation of the cumulus-oocyte complex. During the present study, the effects of the PTGS2/PGE2 pathway on the developmental competence of bovine oocytes were investigated using an in vitro model of maturation, fertilization, and early embryonic development. The specific inhibition of PTGS2 activity ...
Tópico(s): Sperm and Testicular Function
2011 - Oxford University Press | Biology of Reproduction
Fabienne Nuttinck, B. Marquant-Le Guienne, Laëtitia Clément, Pierrette Reinaud, Gilles Charpigny, Bénédicte Grimard,
Prostaglandin E(2) (PGE(2)) and progesterone appear to be critical mediators of cumulus expansion and the resumption of oocyte meiosis. The aim of this study was to identify the types of prostaglandin E synthase (PTGES) expressed in the bovine cumulus-oocyte complex (COC), to characterize their temporal expression during the periconceptional interval using an in vitro model of maturation (IVM) and fertilization (IVF), and to compare their expression with the level of steroidogenic gene expression. Real- ...
Tópico(s): Reproductive System and Pregnancy
2008 - Bioscientifica | Reproduction
Matthieu Legrand, Damien Barraud, Isabelle Constant, Pauline Devauchelle, Nicolas Donat, Mathieu Fontaine, Lætitia Goffinet, Clément Hoffmann, M. Jeanne, Jeanne Jonqueres, Thomas Leclerc, Hugues Lefort, Nicolas Louvet, Marie-Reine Losser, Célia Lucas, Olivier Pantet, Antoine Roquilly, Anne‐Françoise Rousseau, Sabri Soussi, Sandrine Wiramus, Étienne Gayat, Alice Blet,
To provide recommendations to facilitate the management of severe thermal burns during the acute phase in adults and children. A committee of 20 experts was asked to produce recommendations in six fields of burn management, namely, (1) assessment, admission to specialised burns centres, and telemedicine; (2) haemodynamic management; (3) airway management and smoke inhalation; (4) anaesthesia and analgesia; (5) burn wound treatments; and (6) other treatments. At the start of the recommendation-formulation ...
Tópico(s): Wound Healing and Treatments
2020 - Elsevier BV | Anaesthesia Critical Care & Pain Medicine
D. Cornet, Marc Cohen, Arthur Clément, Edouard Amar, Laetitia Fournols, Patrice Clément, Paul Neveux, Y. Ménézo,
The aim of this study is to evaluate whether the MTHFR contribution to male decreased fertility can be attributable to anomalies in sperm nucleus DNA structure in relation to defective methylation.The presence of MTHFR C677T, contributing at most for male infertility, was determined from a venous blood sample, using real-time polymerase chain reaction (PCR). Sperm DNA fragmentation (SDF) and sperm nucleus decondensation index (SDI) measurements were performed using acridine orange and flow cytometry. ...
Tópico(s): Folate and B Vitamins Research
2017 - Springer Science+Business Media | Journal of Assisted Reproduction and Genetics
Stephanie Oerum, Tom Dendooven, Marjorie Catala, Laetitia Gilet, Clément Dégut, Aude Trinquier, Maxime Bourguet, Pierre Barraud, Sarah Cianférani, Ben F. Luisi, Ciarán Condon, Carine Tisné,
The pathways for ribosomal RNA (rRNA) maturation diverge greatly among the domains of life. In the Gram-positive model bacterium, Bacillus subtilis, the final maturation steps of the two large ribosomal subunit (50S) rRNAs, 23S and 5S pre-rRNAs, are catalyzed by the double-strand specific ribonucleases (RNases) Mini-RNase III and RNase M5, respectively. Here we present a protocol that allowed us to solve the 3.0 and 3.1 Å resolution cryoelectron microscopy structures of these RNases poised to cleave ...
Tópico(s): RNA modifications and cancer
2020 - Elsevier BV | Molecular Cell
Jean‐Christophe Tille, André Filipe Vieira, C. Saint-Martin, Lounes Djerroudi, Laëtitia Furhmann, François‐Clément Bidard, Youlia Kirova, A. Tardivon, Fabien Reyal, Matthieu Carton, Anne Vincent‐Salomon,
The prognostic impact of tumor-infiltrating lymphocytes (TILs) within invasive lobular carcinoma (ILC) remains to be better characterized. In estrogen receptor (ER)-negative invasive ductal carcinomas of no special type (IDC-NST), TILs are associated with good prognosis. The aim of this study was to examine TILs in ILC, with particular focus on prognostic and clinicopathologic features. A cohort comprising 459 consecutive ILCs diagnosed in a single institution from 2005 to 2008 met the eligibility criteria ...
Tópico(s): Cancer Cells and Metastasis
2020 - Elsevier BV | Modern Pathology
Sibel Isal, Julien Pierson, Laëtitia Imbert, Alexandra Clément, Charlotte Collet, Sophie Pinel, Nicolas Veran, Aurélie Reinhard, Sylvain Poussier, Guillaume Gauchotte, Steeven Frezier, Gilles Karcher, Pierre‐Yves Marie, Fatiha Maskali,
Tracers triggering αvβ3 integrins, such as certain RGD-containing peptides, were found promising in previous pilot studies characterizing high-grade gliomas. However, only limited comparisons have been performed with current PET tracers. This study aimed at comparing the biodistribution of 18F-fluorodeoxyglucose (18F-FDG) with that of 68Ga-NODAGA-RGD, an easily synthesized monomeric RGD compound with rapid kinetics, in two different rodent models of engrafted human glioblastoma. Nude rodents bearing ...
Tópico(s): Prostate Cancer Treatment and Research
2018 - Springer Science+Business Media | EJNMMI Research
Anthony Jourdon, Carole Petit, Yann Rolland, Chloé Loury, Nicolas Bellahsen, Stéphane Guillot, Laëtitia Le Pourhiet, Clément Ganino,
The tectonic evolution of the Central Asian Orogenic Belt (CAOB) is characterized by the successive accretion of lithospheric blocks, leading to different interpretations about the polarity of subductions during the Paleozoic, the number of microplates and oceanic basins and the timing of tectonic events. This is especially the case in the Tien Shan area. In this paper, we propose new structural maps and cross-sections of Middle and South Kyrgyz Tien Shan (MTS and STS respectively). These cross-sections ...
Tópico(s): High-pressure geophysics and materials
2017 - Elsevier BV | Gondwana Research
Laëtitia Ruppé, Gaël Clément, Anthony Herrel, Laurent Ballesta, Thierry Décamps, Loïc Kéver, Éric Parmentier,
Significance More and more studies stress the potential deleterious effect of anthropogenic sounds on fish acoustic communication. Paradoxically, how the communication between fishes in a community is organized remains extremely poorly known, as studies using passive acoustic recordings are typically restricted to one or two species. At a single site, we were able to follow 16 different vertebrate sounds for 15 days. We demonstrate that the fish population can be distributed into two groups: one ...
Tópico(s): Animal Behavior and Reproduction
2015 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Erica Silvestris, Marc Cohen, D. Cornet, Laetitia Jacquesson-Fournols, Patrice Clément, J. Chouteau, Marc A. Schneider, Thierry Besnard, Y. Ménézo,
Environmental endocrine disrupting chemicals (EDCs), including bisphenol A (BPA), induce DNA methylation errors and oxidative stress, and alter fertility. Animal studies have demonstrated that supporting the one-carbon cycle (1-CC) with appropriate dietary supplements can reduce the effects of EDCs. Anti-Mullerian hormone (AMH), a marker of ovarian functionality, has been tested in subfertile female patients, to control this hypothesis in humans. Fifty-five women with a history of 3–7 years of infertility, ...
Tópico(s): Reproductive Health and Technologies
2017 - Mary Ann Liebert, Inc. | BioResearch open access
David M. Smadja, Laëtitia Mauge, Hilario Nunès, Clément d’Audigier, Karine Juvin, Raphaël Borie, Z. Carton, Sébastien Bertil, Anne Blanchard, Bruno Crestani, Dominique Valeyre, Pascale Gaussem, Dominique Israëł-Biet,
Tópico(s): Eosinophilic Disorders and Syndromes
2012 - Springer Science+Business Media | Angiogenesis
David M. Smadja, Laëtitia Mauge, Pascale Gaussem, Clément d’Audigier, Dominique Israëł-Biet, David S. Celermajer, Damien Bonnet, Marilyne Lévy,
Pulmonary vasodilators in general and prostacyclin therapy in particular, have markedly improved the outcome of patients with pulmonary arterial hypertension (PAH). As endothelial dysfunction is a key feature of PAH, and as endothelial progenitor cells (EPC) may contribute to vascular repair in PAH, we suspected that prostacyclin therapy might enhance EPC numbers and functions. In the present study, objectives were to determine whether EPC may contribute to vasodilator treatment efficacy in PAH.We ...
Tópico(s): Vascular Anomalies and Treatments
2010 - Springer Science+Business Media | Angiogenesis
David M. Smadja, Ivan Bièche, Sophie Susen, Laëtitia Mauge, Ingrid Laurendeau, Clément d’Audigier, Françoise Grelac, Joseph Emmerich, Martine Aiach, Pascale Gaussem,
Abstract The proinflammatory chemokine interleukin 8 exerts potent angiogenic effects on endothelial cells by interacting with its receptors CXCR1 and CXCR2. As thrombin is also a potent inflammatory factor, and as endothelial progenitor cells (EPC) express functional PAR‐1 thrombin receptor, we examined whether PAR‐1 stimulation interferes with the IL‐8 pathway in EPC. EPC were obtained from adult blood (AB) and cord blood (CB). The effect of PAR‐1 stimulation by the peptide SFLLRN on IL‐8, CXCR1 ...
Tópico(s): Platelet Disorders and Treatments
2008 - Wiley | Journal of Cellular and Molecular Medicine
Laëtitia Bréchet, Daniel A. Warren, Clément Stahl, Benoît Burban, Jean-Yves Gorêt, Roberto L. Salomón, Ivan A. Janssens,
Summary Tree stems and soils can act as sources and sinks for the greenhouse gases (GHG) carbon dioxide (CO 2 ), methane (CH 4 ), and nitrous oxide (N 2 O). Since both uptake and emission capacities can be large, especially in tropical rainforests, accurate assessments of the magnitudes and temporal variations of stem and soil GHG fluxes are required. We designed a new flexible stem chamber system for continuously measuring GHG fluxes in a French Guianese rainforest. Here, we describe this new system, which ...
Tópico(s): Fire effects on ecosystems
2021 - Wiley | New Phytologist
Leandro Van Langenhove, Lore T. Verryckt, Laëtitia Bréchet, Élodie A. Courtois, Clément Stahl, Florian Hofhansl, Marijn Bauters, Jordi Sardans, Pascal Boeckx, Erik Fransén, Josep Peñuelas, Ivan A. Janssens,
Atmospheric deposition is an important component of the nutrient cycles of terrestrial ecosystems, but field measurements are especially scarce in tropical regions. In this study we analysed 15 months of precipitation chemistry collected in an old growth tropical forest located in French Guiana. We measured nutrient inputs via bulk precipitation and throughfall and used the canopy budget model to estimate nutrient fluxes via canopy exchange and dry deposition. Based on this method we quantified ...
Tópico(s): Soil and Water Nutrient Dynamics
2020 - Springer Science+Business Media | Biogeochemistry
Guille Peguero, Fernando Coello, Jordi Sardans, Dolores Asensio, Oriol Grau, Joan Llusià, Romà Ogaya, Ifigenia Urbina, Leandro Van Langenhove, Lore T. Verryckt, Clément Stahl, Laëtitia Bréchet, Élodie A. Courtois, Jérôme Chave, Bruno Hérault, Ivan A. Janssens, Josep Peñuelas,
Abstract Soil nutrient availability and functional traits interact in complex ways during the assembly of tree communities hindering our understanding of the implications that this may have for their phylogenetic and functional diversity. We combined abundance, taxonomic, phylogenetic and functional trait data of 222 tree species distributed along nutrient concentration gradients at 24 plots in two tropical forest study sites. We analysed micro and macronutrient concentration in organic and topsoil ...
Tópico(s): Plant Diversity and Evolution
2023 - Wiley | Journal of Ecology
Jean‐François Payen, Yoann Launey, Russell Chabanne, Samuel Gay, Gilles Francony, Laurent Gergelé, Emmanuel Vega, Ambroise Montcriol, David Couret, Vincent Cottenceau, Sébastien Pili‐Floury, Clément Gakuba, Emmanuelle Hammad, Gérard Audibert, Julien Pottecher, Claire Dahyot‐Fizelier, L. Abdennour, Tobias Gauss, Marion Richard, Antoine Vilotitch, Jean‐Luc Bosson, Pierre Bouzat, Marie-Cécile Fevre, Clotilde Schilte, Olivier Vincent, Marie-Christine Hérault, Thomas Mistral, Thibaut Trouvé-Buisson, Julien Picard, Dominique Falcon, Samuel Bersinger, Clément Mourey, Anaïs Adolle, Samia Salah, Pauline Manhes, Angélina Pollet, Frédéric Greco, Kévin Chalard, Bailleul Andréa, Lionel Velly, Nicolas Bruder, Imane Inal, Clément Magand, Laetitia Burnol, Jérôme Morel, Anaèle PREGNY, Jean‐Christophe Ferré, Élise Bannier, Thomas Lebouvier, Sophie Caradec, Claire-Marie Drevet, Abdelouaïd Nadji, Romain Lewandowski, Frédéric Dailler, Romain Carrillon, Florent Gobert, Thomas Ritzenthaler, Mathilde LECLERCQ, Nathalie Dumont, Claire Charpentier, Ionel Alb, N. C. De, Nicolas Declerck, Pierre Boussemart, Julie Bellet, Eric Meaudre-Desgouttes, Erwan D’Aranda, Pierre Esnault, Camille CHARRUAU, Rémy Bellier, Thierry Bénard, Elsa Carise, Sabrina Seguin, Jean Yves Lefrant, Aurélien Daurat, Audrey Ambert, Marie Lebouc, Serge Hautefeuille, Étienne Escudier, F. Bing, Bernard Cosserant, Romain Grobost, Camille Boissy, Marc Bégard, Adrien Guyot, Kevin Lagarde, Elodie Caumon, Thomas Geeraerts, Maxime Pommier, Edouard Naboulsi, Maxime Beilvert, Elodie Parry, Marc Léone, Laurent Zieleskiewicz, Gary Duclos, Charlotte Arbelot, Carole Ichai, Hervé Quintard, Diop Aminata, Louis Puybasset, Grégory Torkomian, Magdalena Szczot, Stéphane Kremer, Guillaume Becker, Stephane Hecketsweiler, Dejan Ilić, Lucie Vettoretti, Coline Grisotto, Romain Asmolov, Vincent Ehinger, N. Laquay, Virginie Chevallier, Zahra Mahlal, Sigismond Lasocki, Anne-Sylvie SCHOLASTIQUE, Thomas GAILLARD, Soizic Gergaud, Emmanuel Barbier, F. Tahon, Alexandre Krainik, Michel Dojat, Irène Troprés, Bernard Vigué, Laura Leo, Vincent Piriou, Antoine Coquerel, Jean‐Luc Cracowski, F. Proust, Michel Mallaret,
Background Optimisation of brain oxygenation might improve neurological outcome after traumatic brain injury. The OXY-TC trial explored the superiority of a strategy combining intracranial pressure and brain tissue oxygen pressure (PbtO2) monitoring over a strategy of intracranial pressure monitoring only to reduce the proportion of patients with poor neurological outcome at 6 months. Methods We did an open-label, randomised controlled superiority trial at 25 French tertiary referral centres. Within ...
Tópico(s): Cardiac Arrest and Resuscitation
2023 - Elsevier BV | The Lancet Neurology
Clément Bonet, Laëtitia Chapel, Lucas Drumetz, Nicolas Courty,
Deep learning methods have become an integral part of computer vision and machine learning research by providing significant improvement performed in many tasks such as classification, regression, and detection. These gains have been also observed in the field of remote sensing for Earth observation where most of the state-of-the-art results are now achieved by deep neural networks. However, one downside of these methods is the need for large amounts of annotated data, requiring lots of labor-intensive ...
Tópico(s): Domain Adaptation and Few-Shot Learning
2022 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Clément Moreau, Laëtitia Giraldi, Hermes Gadêlha,
The inertialess fluid–structure interactions of active and passive inextensible filaments and slender-rods are ubiquitous in nature, from the dynamics of semi-flexible polymers and cytoskeletal filaments to cellular mechanics and flagella. The coupling between the geometry of deformation and the physical interaction governing the dynamics of bio-filaments is complex. Governing equations negotiate elastohydrodynamical interactions with non-holonomic constraints arising from the filament inextensibility. ...
Tópico(s): Cellular Mechanics and Interactions
2018 - Royal Society | Journal of The Royal Society Interface
Céline Bonnet, David Pellerin, Virginie Roth, Guillemette Clément, Marion Wandzel, Laëtitia Lambert, Solène Frismand, Marian Douarinou, Anaïs Grosset, Inès Bekkour, Frédéric Weber, Florent Girardier, Clément Robin, Stéphanie Cacciatore, Myriam Bronner, Carine Bossenmeyer‐Pourié, Natacha Dreumont, Salomé Puisieux, Pablo Iruzubieta, Marie‐Josée Dicaire, François Evoy, Marie‐France Rioux, Armand Hocquel, Roberta La Piana, Matthis Synofzik, Henry Houlden, Matt C. Danzi, Stephan Züchner, Bernard Brais, M. Renaud,
Dominantly inherited GAA repeat expansions in FGF14 are a common cause of spinocerebellar ataxia (GAA-FGF14 ataxia; spinocerebellar ataxia 27B). Molecular confirmation of FGF14 GAA repeat expansions has thus far mostly relied on long-read sequencing, a technology that is not yet widely available in clinical laboratories. We developed and validated a strategy to detect FGF14 GAA repeat expansions using long-range PCR, bidirectional repeat-primed PCRs, and Sanger sequencing. We compared this strategy ...
Tópico(s): Amyotrophic Lateral Sclerosis Research
2023 - Nature Portfolio | Scientific Reports
Leandro Van Langenhove, Ivan A. Janssens, Lore T. Verryckt, Laëtitia Bréchet, Iain P. Hartley, Clément Stahl, Élodie A. Courtois, Ifigenia Urbina, Oriol Grau, Jordi Sardans, Guille Peguero, Albert Gargallo‐Garriga, Josep Peñuelas, Sara Vicca,
Tree growth on weathered soils in lowland tropical forests is limited by low phosphorous (P) availability. However, nutrient manupulation experiments do not always increase the P content in these trees, which raises the question whether trees are taking up added P. In French Guianese lowland rainforest, we measured changes in nitrogen (N) and P availability before and up to two months after N and P fertilizer addition, in soils with intact root systems and in soils where roots and mycorrhizal fungi ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2019 - Elsevier BV | Soil Biology and Biochemistry
Marie Courbebaisse, Aurélie Bourmaud, Jean–Claude Souberbielle, Rébecca Sberro‐Soussan, Valérie Moal, Yannick Le Meur, Nassim Kamar, Laetitia Albano, Antoine Thierry, Jacques Dantal, Clément Danthu, Karine Moreau, Emmanuel Morélon, Anne-Elisabeth Heng, Dominique Bertrand, Nadia Arzouk, Peggy Perrin, Marie-Pascale Morin, Philippe Rieu, Claire Presne, Philippe Grimbert, Didier Ducloux, Matthias Büchler, Moglie Le Quintrec, Nacéra Ouali, Vincent Pernin, Nicolas Bouvier, Antoine Dürrbach, É. Alamartine, Christine Randoux, Virginie Besson, Marc Hazzan, Justine Pages, Sandra Colas, Marie‐Liesse Piketty, Gérard Friedlander, Dominique Prié, Corinne Alberti, Éric Thervet,
Vitamin D sufficiency is associated with a reduced risk of fractures, diabetes mellitus, cardiovascular events, and cancers, which are frequent complications after renal transplantation. The VITALE (VITamin D supplementation in renAL transplant recipients) study is a multicenter double-blind randomized trial, including nondiabetic adult renal transplant recipients with serum 25-hydroxy vitamin D (25(OH) vitamin D) levels of <30 ng/mL, which is randomized 12 to 48 months after transplantation to receive ...
Tópico(s): Neurological Complications and Syndromes
2023 - Elsevier BV | American Journal of Transplantation
Laëtitia Mauge, Florence Sabatier, Pierre Boutouyrie, Clément d’Audigier, Séverine Peyrard, Erwan Bozec, Anne Blanchard, Michel Azizi, Blandine Dizier, Françoise Dignat‐George, Pascale Gaussem, David M. Smadja,
Background aimsCirculating endothelial progenitor cells and especially endothelial colony-forming cells (ECFCs) are promising candidate cells for endothelial regenerative medicine of ischemic diseases, but the conditions for an optimal collection from adult blood must be improved.MethodsOn the basis of a recently reported vascular niche of ECFCs, we hypothesized that a local ischemia could trigger ECFC mobilization from the vascular wall into peripheral blood to optimize their collection for autologous ...
Tópico(s): Mesenchymal stem cell research
2013 - Elsevier BV | Cytotherapy
Kiave-Yune HoWangYin, Céline Loinard, Wineke Bakker, Coralie L. Guérin, José Vilar, Clément d’Audigier, Laëtitia Mauge, Patrick Bruneval, Joseph Emmerich, Bernard Lévy, Jacques Pouysségur, David M. Smadja, Jean‐Sébastien Silvestre,
Upregulation of hypoxia-inducible transcription factor-1α (HIF-1α), through prolyl-hydroxylase domain protein (PHD) inhibition, can be thought of as a master switch that coordinates the expression of a wide repertoire of genes involved in regulating vascular growth and remodeling. We aimed to unravel the effect of specific PHD2 isoform silencing in cell-based strategies designed to promote therapeutic revascularization in patients with critical limb ischemia (CLI). PHD2 mRNA levels were upregulated ...
Tópico(s): Mesenchymal stem cell research
2013 - Oxford University Press | Stem Cells
Solène Evrard, Clément d’Audigier, Laëtitia Mauge, Dominique Israëł-Biet, Coralie L. Guérin, Ivan Bièche, Jason C. Kovacic, A Fischer, Pascale Gaussem, David M. Smadja,
Summary. Background: Transforming growth factor-β1 (TGF-β1) is a profibrotic cytokine that plays a major role in vascular biology, and is known to regulate the phenotype and activity of various vascular cell populations. Because most fibrotic diseases, such as idiopathic pulmonary fibrosis (IPF), are associated with vascular remodeling, and as endothelial progenitor cells (EPCs) may be involved in this process, we investigated the impact of TGF-β1 modulation of EPC angiogenic properties. Methods: TGF- ...
Tópico(s): Kruppel-like factors research
2012 - Elsevier BV | Journal of Thrombosis and Haemostasis
Y. Ménézo, Pasquale Patrizio, Silvia Álvarez, Edouard Amar, Michel Brack, C. Brami, J. Chouteau, Arthur Clément, Patrice Clément, Marc Cohen, D. Cornet, Brian Dale, Guiseppe D' Amato, Laetitia Jacquesson-Fournols, P. Marès, Paul Neveux, Jean Clement Sage, Edouard J. Servy, To Minh Huong, Géraldine Viot,
MTHFR, one of the major enzymes in the folate cycle, is known to acquire single-nucleotide polymorphisms that significantly reduce its activity, resulting in an increase in circulating homocysteine. Methylation processes are of crucial importance in gametogenesis, involved in the regulation of imprinting and epigenetic tags on DNA and histones. We have retrospectively assessed the prevalence of MTHFR SNPs in a population consulting for infertility according to gender and studied the impact of the ...
Tópico(s): Assisted Reproductive Technology and Twin Pregnancy
2021 - Springer Science+Business Media | Journal of Assisted Reproduction and Genetics