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Artigo Acesso aberto Revisado por pares

Hadda‐Imene Ouzari, Ameur Chérif, Diego Mora,

Aims: To evaluate the autolytic properties of Lactococcus lactis strains isolated from artisan Tunisian dairy products, their peptidoglycan hydrolase content and their activity spectrum. Methods and Results: The autolytic phenotype of Lactococcus strains was evaluated under starvation conditions in potassium ... allowing the identification of high and low autolytic Lactococcus lactis strains. Peptidoglycan hydrolase content was evaluated by ... 5. The substrate specificity of peptidoglycan hydrolase from Lactococcus strains was evaluated in renaturing SDS-PAGE incorporating ...

Tópico(s): Genomics and Phylogenetic Studies

2002 - Oxford University Press | Journal of Applied Microbiology

Artigo Revisado por pares

P. Descheemaeker, Bruno Pot, A.M. Ledeboer, Theo Verrips, K. Kersters,

... of whole-cell proteins for the identification of Lactococcus strains to subspecies level, a total of 99 Lactococcus lactis subsp. lactis and subsp. cremoris strains were ... bacteria of the genera Aerococcus, Carnobacterium, Enterococcus, Lactobacillus, Lactococcus, Leuconostoc, Pediococcus, Tetragenococcus, and Vagococcus. Numerical analysis of ... patterns clearly discriminated all species investigated. Seventy two Lactococcus lactis strains were assigned to their respective Lactococcus lactis subspecies. Twelve strains were originally incorrectly identified ...

Tópico(s): Bacterial Infections and Vaccines

1994 - Elsevier BV | Systematic and Applied Microbiology

Artigo Acesso aberto

Roland J. Siezen, Herwig Bachmann,

... final product. Cheese production makes use of predominantly Lactococcus lactis. It is the major component of cheese ... GenBank code Size (kb) GC% Origin/use Reference Lactococcus lactis lactis/IL1403 NC_002662 2365 35 Cheese ... to a substantial gene loss especially in the Lactococcus–Streptococcus branch (Makarova and Koonin, 2007). Gene loss ... from the genus St reptococcus to the genus Lactococcus (Ammann et al., 2008). As bacteriophages can cause ... Plasmid transfer via transduction from Streptococcus thermophilus to Lactococcus lactis. J Bacteriol 190: 3083– 3087. CrossrefCASPubMedWeb of ...

Tópico(s): Microbial Metabolic Engineering and Bioproduction

2008 - Wiley | Microbial Biotechnology

Artigo Revisado por pares

Yimin Cai, Jin‐Song Yang, Huili Pang, Maki Kitahara,

... indicated that the strains belonged to the genus Lactococcus. These strains shared similar phenotypic characteristics and exhibited ... with those of other species of the genus Lactococcus. On the basis of phylogenetic analysis the three strains grouped with other members of the genus Lactococcus. Lactococcus lactis and Lactococcus garvieae were the most closely related species, sharing ... from reference strains of species of the genus Lactococcus and DNA-DNA hybridization studies indicated that the ... 415 represent a novel species of the genus Lactococcus, for which the name Lactococcus fujiensis sp. nov. ...

Tópico(s): Genomics and Phylogenetic Studies

2010 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Acesso aberto Revisado por pares

Anton Steen, Elena Wiederhold, Tejas Gandhi, Rainer Breitling, Dirk Jan Slotboom,

... produced human CFTR in the prokaryotic expression host Lactococcus lactis. The full-length protein was detected in ... produced human CFTR in the prokaryotic expression host Lactococcus lactis. The full-length protein was detected in ... 5Kunji E.R. Slotboom D.J. Poolman B. Lactococcus lactis as host for overproduction of functional membrane ... a project to express CFTR in the bacterium Lactococcus lactis. cystic fibrosis transmembrane conductance regulator n-dodecyl- ... Vos W.M. Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin.Appl. ...

Tópico(s): Bacterial biofilms and quorum sensing

2010 - Elsevier BV | Molecular & Cellular Proteomics

Artigo Revisado por pares

C Frossard, Lothar Steidler, Philippe Eigenmann,

... the gut.ObjectivesWe hypothesized that administration of a Lactococcus lactis transfected to secrete murine IL-10 could ... cholera toxin, young mice were administered the transfected Lactococcus lactis. Antigen-induced anaphylaxis after oral challenge assessed ... spleen and in Peyer patches.ResultsPretreatment with transfected Lactococcus lactis contributed to diminish anaphylaxis significantly, and inhibit ... IgE and IgG1 production strongly. In addition, transfected Lactococcus lactis increased the production of antigen-specific IgA ...

Tópico(s): Eosinophilic Esophagitis

2007 - Elsevier BV | Journal of Allergy and Clinical Immunology

Artigo Acesso aberto Revisado por pares

Toshitaka Odamaki, S. Yonezawa, Maki Kitahara, Yoshiyuki Sugahara, Jin‐zhong Xiao, Tomoko Yaeshima, Keiji Iwatsuki, Moriya Ohkuma,

Aims: The gram‐positive bacterial genus Lactococcus has been taxonomically classified into seven species (Lactococcus lactis, Lactococcus garvieae, Lactococcus piscium, Lactococcus plantarum, Lactococcus raffinolactis, Lactococcus chungangensis and Lactococcus fujiensis). This study aimed to develop a novel ...

Tópico(s): Infective Endocarditis Diagnosis and Management

2011 - Oxford University Press | Letters in Applied Microbiology

Artigo Acesso aberto Revisado por pares

Gozde Koral, Yasin Tuncer,

... p. 1044-1053 Original Article Nisin Z-Producing Lactococcus lactis Subsp. Lactis GYl32 Isolated from Boza Gozde ... Copy URL Abstract In this study, bacteriocin-producing Lactococcus lactis subsp. lactis GYL32 strain was isolated from ... is the best-studied bacteriocin produced by some Lactococcus lactis strains and has been used for food ... Davidson, B.E. 1992. Rapid genomic fingerprinting of Lactococcus lactis strains by arbitrarily primed polymerase chain reaction ... the production of a nisin-like bacteriocin by Lactococcus lactis subsp. lactis A164 isolated from kimchi. J. ...

Tópico(s): Meat and Animal Product Quality

2012 - Wiley | Journal of Food Processing and Preservation

Artigo Acesso aberto Revisado por pares

Giampietro Pellizzer, P. Benedetti, Francesca Biavasco, Vinicio Manfrin, Marzia Franzetti, Mariuccia Scagnelli, Claudio Scarparo, Fausto de Lalla,

... streptococci) and, more recently, transferred to the genus Lactococcus [1Schleifer KH Kraus J Dvorak C Kilpper-Bälz ... Streptococcus lactis and related streptococci to the genus Lactococcus gen.nov. Syst Appl Microbiol. 1985; 6: 183-195Crossref Scopus (355) Google Scholar]. Lactococcus lactis subsp. lactis and L. lactis subsp. cremoris- ... cheese starters and commonly included in foodstuffs. Although Lactococcus species are generally thought to be non-pathogenic ... 3Facklam RR Pigott N Collins MD Identification of Lactococcus species from human sources.in: Orefici G New ...

Tópico(s): Diphtheria, Corynebacterium, and Tetanus

1996 - Elsevier BV | Clinical Microbiology and Infection

Carta Acesso aberto Revisado por pares

Au Mofredj, Daoud Baraka, J.F. Cadranel, Patrice Lemaître, G. Kloeti, Jean Loup Dumont,

Lactococcus garvieae was first isolated from cases of bovine mastitis, and it may also infect several species ... Eldar A. Ghittino C. Bercovier H. Identification of Lactococcus garvieae by PCR.J Clin Microbiol. 1998; 36: ... Goria M. Ghittino C. et al.Biodiversity of Lactococcus garvieae strains isolated from fish in Europe, Asia, ... J.A. Facklam R.R. Antimicrobial susceptibilities of Lactococcus lactis and Lactococcus garvieae and a proposed method to discriminate between ... Ratzan K.R. Sharp S.E. Saiz E. Lactococcus garvieae endocarditis report of case and review of ...

Tópico(s): Aquaculture disease management and microbiota

2000 - Elsevier BV | The American Journal of Medicine

Artigo Acesso aberto Revisado por pares

Aurora Meucci, Miriam Zago, Lia Rossetti, Maria Emanuela Fornasari, Barbara Bonvini, Flavio Tidona, Milena Povolo, Giovanna Contarini, Domenico Carminati, Giorgio Giraffa,

... indicated that these isolates belonged to the genus Lactococcus. Strain 117(T) was closely related to Lactococcus fujiensis, Lactococcus lactis subsp. lactis, L. lactis subsp. cremoris, L. lactis subsp. hordniae, L. lactis subsp. tructae and Lactococcus taiwanensis, showing 93-94% and 82-89% 16S ... respectively. Strain 4195(T) was closely related to Lactococcus chungangensis, Lactococcus raffinolactis, Lactococcus plantarum and Lactococcus piscium, showing 92-98% and ...

Tópico(s): Gut microbiota and health

2015 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marjory Xavier Rodrigues, S.F. Lima, Catherine H. Higgins, Solange Guidolin Canniatti‐Brazaca, R.C. Bicalho,

Abstract The bacterium Lactococcus lactis is widely used in food production and in medical applications, and is considered safe for human and animal use. However, studies have also linked Lactococcus bacteria to infection. For example, certain variants of Lactococcus species have been associated with bovine mastitis (e.g., Lactococcus lactis and Lactococcus garvieae ). In this study, we investigated an outbreak of bovine mastitis thought to be associated with Lactococcus bacteria by using microbiological and molecular techniques. We ...

Tópico(s): Genomics and Phylogenetic Studies

2016 - Elsevier BV | Journal of Dairy Science

Artigo Acesso aberto Revisado por pares

Sophea Pheng, Ho Le Han, Doo‐Sang Park, Chang Ho Chung, Song‐Gun Kim,

... strain S-13T had the highest similarity to Lactococcus taiwanensis 0905C15T (97.9 %), Lactococcus lactis subsp. tructae L105T (97.6 %), Lactococcus lactis subsp. cremoris NCDO 607T (97.5 %), Lactococcus lactis subsp. hordniae NBRC 100931T (97.2 %), and Lactococcus lactis subsp. lactis JCM 5805T (97.2 %). The ... the other species and subspecies in the genus Lactococcus. The DNA-DNA relatedness between S-13T and ... 13T represents a novel species in the genus Lactococcus for which the name Lactococcus kimchii sp. nov. (=KCTC 21096T=NBRC 113348T) is ...

Tópico(s): Oral microbiology and periodontitis research

2019 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Revisado por pares

Donghui Ma, Yue Jiang, Saeed Ahmed, Wen Qin, Yaowen Liu,

... sodium carboxymethylcellulose, and collagen. In addition, we evaluated Lactococcus lactis, which produces bacteriocin and lactic acid. Lactococcus lactis-containing edible films were constructed via tape- ... films were measured to examine the effects of Lactococcus lactis on film matrices. Further, we determined the survival of Lactococcus lactis after the film-drying process and viability of Lactococcus lactis stored for 24 days at 4 °C. Our results indicate that incorporation of Lactococcus lactis changed the physical properties of edible films. ...

Tópico(s): Protein Hydrolysis and Bioactive Peptides

2019 - Elsevier BV | International Journal of Biological Macromolecules

Artigo Revisado por pares

Ting Ting Li, Wen Tian, Chun Tao Gu,

Currently, Lactococcus lactis contains four subspecies: L. lactis subsp. lactis , L. lactis subsp. hordniae , L. lactis subsp. cremoris and ... L. lactis subsp. hordniae , L. lactis subsp. lactis , Lactococcus taiwanensis , Lactococcus kimchii , Lactococcus allomyrinae , Lactococcus protaetiae , Lactococcus hircilactis , Lactococcus fujiensis and ...

Tópico(s): Infective Endocarditis Diagnosis and Management

2019 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Acesso aberto Revisado por pares

Maik Hilgarth, Victoria Werum, Rudi F. Vogel,

... analysis revealed a distinct lineage within the genus Lactococcus , with Lactococcus piscium and Lactococcus plantarum as closest relatives. Results indicated that they ... 78 % the most closely related type strain of Lactococcus piscium , respectively. However, the ANIb value between the ... 2.1615 T , and the type strain of Lactococcus piscium was only 94.3 and 92.0 %, ... and the most closely related type strain of Lactococcus piscium was only 59.9 and 48.9 %, ... isolates represent two novel species of the genus Lactococcus , for which the names Lactococcus carnosus sp. nov ...

Tópico(s): Oral microbiology and periodontitis research

2020 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Revisado por pares

Junchang Feng, Shasha Liu, Chaojie Zhu, Zhongliang Cai, Wenshan Cui, Xulu Chang, Xiao Yan, Chaobin Qin, Jianxin Zhang, Guoxing Nie,

Based on beneficial effects of Lactococcus spp. and their extracellular polysaccharides on common carp (Cyprinus carpio L.) in previous studies, the main purpose of this paper was ... the functions of single or multi-strains of Lactococcus spp. on the growth performance, glucose absorption and ... that when the fish consumed diets containing single (Lactococcus lactis Q-8, L. lactis Q-9, L. lactis Z-2) or multi-strains of Lactococcus spp. (5 × 108 CFU g−1 of feed) ... While the feed conversion ratio (FCR) of all Lactococcus spp. addition groups was significantly lower than that ...

Tópico(s): Animal Nutrition and Physiology

2021 - Elsevier BV | Aquaculture

Revisão Acesso aberto Revisado por pares

H. Guérin, Saulius Kulakauskas, Marie‐Pierre Chapot‐Chartier,

... cocci belonging to the genera Streptococcus, Enterococcus, or Lactococcus, synthesize WTA in small amounts or not at ... in nonpathogenic food lactic acid bacteria such as Lactococcus lactis (formerly Streptococcus lactis, group N Streptococcus) (14Sadovskaya ... wall: A rhamnan polysaccharide trapped inside peptidoglycan of Lactococcus lactis.MBio. 2017; 8: e01303-e01317Crossref PubMed Scopus ( ... wall: A rhamnan polysaccharide trapped inside peptidoglycan of Lactococcus lactis.MBio. 2017; 8: e01303-e01317Crossref PubMed Scopus ( ...

Tópico(s): Carbohydrate Chemistry and Synthesis

2022 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Taylor Abraham, Zeinab Yazdi, Eric M. Littman, Khalid Shahin, Taylor I. Heckman, Eva Marie Quijano Cardé, Diễm Thư Nguyễn, Ruixue Hu, Mark Adkison, Tresa Veek, Kavery Mukkatira, Christine Richey, Kevin Kwak, Haitham H. Mohammed, César Ortega-Santana, Rubén Avendaño‐Herrera, William Keleher, Véronique LePage, Ian A. Gardner, Timothy J. Welch, Esteban Soto,

... the study aimed to detect the presence of Lactococcus petauri, L. garvieae, and L. formosensis in fish ( ... objective was to compare the virulence of the Lactococcus spp. in Rainbow Trout Oncorhynchus mykiss and Largemouth ... Standard bacterial culture methods were used to isolate Lactococcus spp. from brain and posterior kidney of sampled ... lakes. Quantitative PCR (qPCR) was utilized to detect Lactococcus spp. DNA in fish tissues and environmental samples ... 4), and monitored for 14 days postchallenge (dpc). Lactococcus garvieae was isolated from the brains of two ...

Tópico(s): Identification and Quantification in Food

2023 - Wiley | Journal of Aquatic Animal Health

Artigo Revisado por pares

Tariq Aziz, Haider Khan, S. M. Bakhtair, M. Naurin,

... Lactobacillus acidophilus (25%), Lactobacillus delbrueckii ssp. bulgaricus (21%), Lactococcus lactis ssp. cremoris (21%), Lactococcus lactis ssp. lactis (19%), and Streptococcus thermophilus (14%). ... in cow milk samples were, Streptococcus thermophilus (34%), Lactococcus lactis ssp. lactis (28%), Lactobacillus delbrueckii ssp. bulgaricus (28%) and Lactococcus lactis ssp. cremoris (10%). Isolates of sheep milk were identified as Lactococcus lactis ssp. lactis (36%), Lactococcus lactis ssp. cremoris (32%), Lactobacillus acidophilus (22%) and ...

Tópico(s): Protein Hydrolysis and Bioactive Peptides

2009 - ELEWA BIOSCIENCES, F.a.C.T.LTD | The Journal of Animal and Plant Sciences

Artigo Acesso aberto Revisado por pares

Maytiya Konkit, Woo Jin Choi, Wonyong Kim,

... can metabolize acetaldehyde, produce from ethanol to acetate. Lactococcus species, which is commonly used as a starter ... determined. In this study, the ALDH activity of Lactococcus chungangensis CAU 28(T) and 11 other type strains in the genus Lactococcus was studied. Only 5 species, 3 of dairy origin (Lactococcus lactis ssp. lactis KCTC 3769(T), Lactococcus lactis ssp. cremoris KCCM 40699(T), and Lactococcus raffinolactis DSM 20443(T)) and 2 of nondairy origin (Lactococcus fujiensis NJ317(T) and L. chungangensis CAU 28( ...

Tópico(s): Microbial Metabolites in Food Biotechnology

2015 - Elsevier BV | Journal of Dairy Science

Artigo Acesso aberto Revisado por pares

Michael Bandell, M. E. Lhotte, C. Marty-Teysset, Ana Veyrat, Hervé Prévost, Véronique Dartois, Charles Diviès, W N Konings, Juke S. Lolkema,

... energetics of citrate metabolism in the related organism Lactococcus lactis are contradictory, and this study was performed ... to the known sequence of the CitP of Lactococcus lactis. The cloned gene was expressed in a Lactococcus lactis Cit- strain, and the gene product was ... it is embedded in the cytoplasmic membrane of Lactococcus lactis. Furthermore, using the same criteria and experimental approach, we demonstrated that the endogenous CitP of Lactococcus lactis has the same properties, showing that the ...

Tópico(s): Microbial Metabolites in Food Biotechnology

1998 - American Society for Microbiology | Applied and Environmental Microbiology

Artigo Acesso aberto Revisado por pares

Jie Yu, Yuqin Song, Yan Ren, Yanting Qing, Wenjun Liu, Zhihong Sun,

... genomic diversity of different species within the genus Lactococcus and the relationships between genomic differentiation and environmental ... unclear. In this study, type isolates of ten Lactococcus species/subspecies were sequenced to assess their genomic ... The total genome sizes varied between 1.99 (Lactococcus plantarum) and 2.46 megabases (Mb; L. lactis ... Analysis of genome dynamics indicated that the genus Lactococcus has an open pan-genome, while the core ... Comparative genomics indicated that species in the genus Lactococcus had high degrees of diversity in genome size, ...

Tópico(s): Oral microbiology and periodontitis research

2017 - BioMed Central | BMC Microbiology

Artigo Acesso aberto Revisado por pares

Maytiya Konkit, Woo Jin Choi, Wonyong Kim,

... ethanol to acetaldehyde. However, the ADH activity of Lactococcus spp., except Lactococcus lactis ssp. lactis, has not been widely determined, ... In the current study, the ADH activity of Lactococcus chungangensis CAU 28(T) and 11 reference strains from the genus Lactococcus was determined. Only 5 strains, 3 of dairy ... L. lactis ssp. cremoris KCCM 40699(T), and Lactococcus raffinolactis DSM 20443(T), and 2 of nondairy origin, Lactococcus fujiensis NJ317(T) and Lactococcus chungangensis CAU 28(T) KCTC 13185(T), showed ...

Tópico(s): Microbial Metabolites in Food Biotechnology

2015 - Elsevier BV | Journal of Dairy Science

Artigo Acesso aberto Revisado por pares

Satoko Noda, Fumiya Koyama, Chihiro Aihara, Nao Ikeyama, Masahiro Yuki, Moriya Ohkuma, Mitsuo Sakamoto,

... and phenotypically. Strain Hs20B0-1T was related to Lactococcus piscium DSM 6634T showing 96.3 and 84. ... sequences, respectively. Strain Hs30E4-3T was related to Lactococcus plantarum DSM 20686T showing 94.8 and 82. ... are distinguishable from each other and other established Lactococcus species phylogenetically and phenotypically. In conclusion, two novel species of the genus Lactococcus are proposed, namely Lactococcus insecticola Hs20B0-1T (=JCM 33485T=DSM 110147T) and Lactococcus hodotermopsidis Hs30E4-3T (=JCM 33486T=DSM 110148T), respectively.

Tópico(s): Insect and Pesticide Research

2020 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Revisão Acesso aberto Revisado por pares

Wahib Lahlou, Abderrahim Bourial, Taib Maaouni, Ahmed Bensaad, Ilham Bensahi, Mohamed Sabry, M. Miguil,

... two decades, several cases of infections caused by Lactococcus lactis have been reported. This Gram-positive coccus ... and the microbiological study of the pus revealed Lactococcus lactis subsp. cremoris . Three days after admission, control ... and the evolution was clinically and biologically favorable. Lactococcus lactis subsp. cremoris , formerly known as Streptococcus cremoris , ... cause of human infections. The first case of Lactococcus lactis cremoris endocarditis was reported in 1955. This ... only 13 cases of infectious endocarditis due to Lactococcus lactis , with subsp. cremoris identified in four of ...

Tópico(s): Otolaryngology and Infectious Diseases

2023 - BioMed Central | Journal of Medical Case Reports

Artigo Revisado por pares

Giuseppe Blaiotta, Olimpia Pepe, Gianluigi Mauriello, Francesco Villani, Rosamaria Andolfi, Giancarlo Moschetti,

... representing 11 different species belonging to the genera Lactococcus, Streptococcus, Lactobacillus, Enterococcus and Leuconostoc, and 127 wild ... sequences vary greatly, in size and sequence, among Lactococcus garvieae, Lactococcus raffinolactis, Lactococcus lactis as well as other streptococci from dairy ...

Tópico(s): Identification and Quantification in Food

2002 - Elsevier BV | Systematic and Applied Microbiology

Artigo Acesso aberto Revisado por pares

Sung‐Lim Cho, S.-W. Nam, Jae Hyun Yoon, Jung‐Sook Lee, Ampaitip Sukhoom, Wonyong Kim,

... identified tentatively as a member of the genus Lactococcus. Comparative 16S rRNA gene sequence analysis showed that ... CAU 28T and the type strains of recognized Lactococcus species ranged from 90.4 to 97.2 %. ... 1 % relatedness to the type strains of recognized Lactococcus species. The rep-PCR fingerprints revealed that strain CAU 28T was well separated from reference Lactococcus species. The combined genotypic and phenotypic data indicate ... 28T represents a novel species of the genus Lactococcus, for which the name Lactococcus chungangensis sp. nov. ...

Tópico(s): Probiotics and Fermented Foods

2008 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Artigo Revisado por pares

Benoît Foligné, Rodrigue Dessein, Michaël Marceau, Sabine Poiret, Mathias Chamaillard, Bruno Pot, Michel Simonet, Catherine Daniel,

... Methods: We genetically engineered the food-grade bacterium Lactococcus lactis to secrete the LcrV protein from the ... Methods: We genetically engineered the food-grade bacterium Lactococcus lactis to secrete the LcrV protein from the ... we genetically engineered a food-grade strain of Lactococcus lactis (a nonpathogenic, noninvasive, and noncolonizing gram-positive ... W. Improved cloning vectors and transformation procedure for Lactococcus lactis.J Appl Bacteriol. 1993; 74: 629-636Crossref ... usp45, a gene encoding a secreted protein from Lactococcus lactis subsp lactis MG1363.Gene. 1990; 95: 155- ...

Tópico(s): Pharmacological Effects of Natural Compounds

2007 - Elsevier BV | Gastroenterology

Artigo Acesso aberto Revisado por pares

Karen K. Yam, F. Hugentobler, Philippe Pouliot, Andrew M. Stern, Jean-Daniel Lalande, Greg Matlashewski, Martin Olivier, Benoit Cousineau,

... the non-colonizing, non-pathogenic Gram-positive bacterium Lactococcus lactis. A truncated, codon-optimized version of the ... from Leishmania donovani was engineered for expression in Lactococcus lactis in three different subcellular compartments: in the ... to the cell wall. These three A2-expressing Lactococcus lactis strains were tested for their ability to ... in BALB/c mice. Subcutaneous immunization with live Lactococcus lactis expressing A2 anchored to the cell wall ... antigen-specific serum antibodies. It was demonstrated that Lactococcus lactis-based vaccines are a feasible approach in ...

Tópico(s): Research on Leishmaniasis Studies

2011 - Microbiology Society | Journal of Medical Microbiology