C. D. Binnie, W. van Emde Boas, D. G. A. Kasteleijn‐Nolste‐Trenite, R. Korte, J. W. A. Meijer, H. Meinardi, A A Miller, J. Overweg, A. W. Peck, Astrid Van Wieringen, W. C. Yuen,
... exacerbation de doléances préexistantes. RESUMEN Dosis únicas de lamotrigina de 120 ó 240 mg han sido administradas ... 2 de ellos) después de la administración de lamotrigina. También se observó una reducción en la frecuencia ... durante 24 horas después de la administración de lamotrigina en 5 sujetos con puntas interictales frecuentes. La ... no se afectó por una dosis única de lamotrigina. En 5 enfermos se observaron ligeros efectos colaterales ...
Tópico(s): Drug Transport and Resistance Mechanisms
1986 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Túlio César Azevedo Alves, Giselli Santos Azevedo, Emannuela Santiago de Carvalho,
... o placebo. Em três estudos controlados comparando a lamotrigina, o topiramato e o cloridrato de proparacaína ao placebo, somente a lamotrigina mostrou-se superior a ele. O dextrometafano foi ... o tratamento da neuralgia do trigêmeo, estando a lamotrigina e a pimozida indicadas em casos refratários à ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2004 - Elsevier BV | Brazilian Journal of Anesthesiology
Rita Rodrigues, Pedro Amador, Leandro Rassi, Filipe Seixo, Leonor Parreira, Nuno Moreira Fonseca, Luís Soares,
... de 52 anos com síndrome depressiva, medicada com lamotrigina há cerca de cinco meses, que recorre à ... objetivou o mesmo padrão. Com a interrupção da lamotrigina, houve reversão do padrão eletrocardiográfico típico de Brugada. ... estar atualmente contraindicada na síndrome de Brugada, a lamotrigina é um antidepressivo que bloqueia canais de sódio, ...
Tópico(s): ECG Monitoring and Analysis
2013 - Elsevier BV | Revista Portuguesa de Cardiologia (English Edition)
Produção Nacional
Revisado por pares
provavelmente ocasionado pela toxicidade da lamotrigina secundaria ao aumento abrupto da dosagem do acido valproico.Relato de caso: AML, 36 anos, sexo masculino, leucodermico, advogado, com diagnostico ... 78 ug/ml, mas o nivel serico da lamotrigina nao pode ser averiguado. Com a suspeita de toxicidade da lamotrigina secundaria ao aumento abrupto do acido valproico, ambas ... do quadro clinico em tres dias.Discussao: A lamotrigina tem se apresentado nos ultimos anos como um ...
Tópico(s): Bipolar Disorder and Treatment
2008 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
A A Miller, P L Wheatley, David A. Sawyer, Martin G. Baxter, Barbara Roth,
... des crises partielles ou généralisées tonicocloniques. RESUMEN La lamotrigina [3,5‐diamino‐6‐(2,3‐diclorofenil)‐1, ... de estructura nueva. El petfil anticonvulsivo de la lamotrigina (LTG), tras la administración oral en dos tests ...
Tópico(s): Neuroscience and Neuropharmacology Research
1986 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Ricardo Alberto Moreno, Doris Hupfeld Moreno, Márcia Britto de Macedo Soares, Roberto Ratzke,
... sobre o uso de anticonvulsivantes (valproato, carbamazepina, oxcarbazepina, lamotrigina, gabapentina, topiramato, clonazepam) e antipsicóticos atípicos (clozapina, risperidona, ... o valproato são eficazes na mania aguda. A lamotrigina parece reduzir ciclagem e ser eficaz em episódios ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2004 - Associação Brasileira de Psiquiatria | Brazilian Journal of Psychiatry
Janusz Rybakowski, Wiesław Jerzy Cubała, Piotr Gałecki, Joanna Rymaszewska, Jerzy Samochowiec, Agata Szulc, Dominika Dudek,
... Depresję w okresie ciąży można leczyć kwetiapiną lub lamotriginą lub dodać lek przeciwdepresyjny do stosowanego leczenia normotymicznego. ... kwetiapina, sertralina i paroksetyna, a wysoki – lit i lamotrigina. W przypadku wystąpienia psychozy poporodowej konieczna jest hospitalizacja ...
Tópico(s): Pregnancy and Medication Impact
2019 - Polish Psychiatric Association | Psychiatria Polska
Produção Nacional
Elie Cheniaux, Allan Dias, José Luiz Martins Lessa, Márcio Versiani,
Em ensaios clínicos controlados com pacientes bipolares, a lamotrigina tem demonstrado eficácia no tratamento da fase aguda ... clínicos da literatura científica, os quais associam a lamotrigina a uma taxa muito baixa de virada para ...
Tópico(s): Electroconvulsive Therapy Studies
2005 - Sociedade de Psiquiatria do Rio Grande do Sul | Revista de Psiquiatria do Rio Grande do Sul
M.J. Leach, Caroline M. Marden, A A Miller,
... étiologie de l'épilepsie est discuté. RESUMEN La lamotrigina [LTG; 3,5‐diamino‐6‐(2,3‐diclorofenil)‐ ...
Tópico(s): Synthesis and pharmacology of benzodiazepine derivatives
1986 - Wiley | Epilepsia
Produção Nacional
Revisado por pares
Susana Barreto Mory, Carlos A.M. Guerreiro, Li Li, Ricardo Afonso Teixeira, Alberto Costa, Tânia Aparecida Marchiori de Oliveira Cardoso, Fernando Cendes,
... 25 pacientes apresentaram melhora significativa. A associação de lamotrigina em três destes pacientes propiciou redução significativa da ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2002 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
José Ángel Mauri Llerda, María Dolores Morales Martínez, Javier Salas Puig, Francisco Javier Vadillo Olmo, AA.VV. Campos, Maria Carmen G. Diaz, AA.VV. Fernández, José Manuel Paz González, Oscar Vega López, Silvia Cobaleda, Grupo de Investigadores de Estudio Grupo de Investigadores de Estudio,
The efficacy and tolerability of lamotrigine (LTG) in monotherapy and in combination therapy have been demonstrated in clinical trials. The aim of the ERELMO study was to retrospectively evaluate the effectiveness and safety of LTG, as monotherapy in the control of epileptic seizures in routine clinical practice in Spain.446 clinical records were selected of patients with LTG treatment in the twelve months previously to the beginning of the study. The main endpoints retrospectively analyzed were ...
Tópico(s): Neuroscience and Neuropharmacology Research
2008 - Viguera Publishers | Revista de Neurología
Produção Nacional
Revisado por pares
Osvaldo J. M. Nascimento, Marco Orsini, Giseli Quintanilha,
Tópico(s): Shoulder Injury and Treatment
2010 - Viguera Publishers | Revista de Neurología
Miguel Ángel Ruiz Ginés, García S. García, Juan Antonio Ruiz Ginés, Tze Kiong, E. Fernández Rodríguez,
... síndrome depresivo exógeno, en tratamiento conjunto con Carbamacepina, Lamotrigina y Venlafaxina que sufre cuadro sincopal secundario a ...
Tópico(s): Neurological and metabolic disorders
2007 - SciELO | Anales de Medicina Interna
Produção Nacional
Revisado por pares
... sobre a substituição de uma nova DAE, a lamotrigina. O nível de evidência é fraco, baseado em ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2007 - SciELO | Journal of Epilepsy and Clinical Neurophysiology
Produção Nacional
Paulo José Ribeiro Teixeira, Fábio Lopes Rocha,
... o haloperidol, a ziprasidona, o aripiprazol e a lamotrigina não estão associadas a ganho importante de peso ...
Tópico(s): Schizophrenia research and treatment
2006 - Sociedade de Psiquiatria do Rio Grande do Sul | Revista de Psiquiatria do Rio Grande do Sul
Daniel Jorge Luis Serrani Azcurra,
Objective: To determine the safety of lamotrigine rechallenge after a first episode of skin rash in bipolar patients.Method: An open cases prospective study was conducted with patients, who developed a skin rash when first treated with lamotrigine, were refractory to other treatments, and were offered lamotrigine rechallenge using a different dose titration.Additionally a review was performed on previous skin rash management strategies and lamotrigine rechallenge reports.Results: Every 3 out of ...
Tópico(s): Schizophrenia research and treatment
2012 - Elsevier BV | Revista de Psiquiatría y Salud Mental
Gustavo Mönckeberg F, Antonio Vukusich C, Gonzalo Valls G, Helmar Rosenberg G,
Acute interstitial nephritis associated to lamotrigine use. Report of one caseAcute interstitial nephritis is a mononuclear and sterile inflammation of the renal interstice caused by drugs, infections or immune phenomena.The clinical presentation is characterized by the triad of rash, fever and eosinophilia.We report a 32 years old man, in treatment with lamotrigine for depression, admitted to the hospital due to fever, abdominal pain, jaundice, cutaneus rash and malaise.Due to an oliguric renal ...
Tópico(s): Sarcoidosis and Beryllium Toxicity Research
2004 - Q16635223 | Revista médica de Chile
Alexandre García Escrivá, Nicolás López Hernández, María Álvarez Saúco, Ana Pampliega Pérez, Clara Oliver Navarrete, M. Asensio, José Manuel Moltó Jordà, Antonio Palao Sánchez,
Lamotrigine (LTG) is a new antiepileptic drug indicated in all kinds of partial and generalised clonic-tonic seizures, both in monotherapy and polytherapy. Between 20 and 30% of epileptic patients have poor control over their seizures despite adequate treatment.We report on our experience regarding the long-term efficacy and tolerability of LTG in refractory seizures.We conducted a consecutive 10-year study of patients who began LTG therapy following poor control of their seizures, in spite of being ...
Tópico(s): Coordination Chemistry and Organometallics
2004 - Viguera Publishers | Revista de Neurología
M.A. Fernández-Galán, Guillermo Martín–Núñez, M.R. López-López, Fernando Raga Castellanos,
Tópico(s): Blood groups and transfusion
2000 - Elsevier BV | Medicina Clínica
C. Fernández Calvo, Javier Olascoaga Urtaza, A. Resano, Javier Urcola Echevarria, A. Turneu, J.I. Pijoan Zubizarreta,
Lamotrigine (LTG) is a new antiepileptic of habitual use in monotherapy as much in partial epileptic as in generalised, which presents among other adverse effects: slight rashes and less frequently severe rashes such as Stevens-Johnson syndrome and Lyell syndrome or toxic epidermal necrolysis, above all in combination with valproate (VPA).A 44-yr-old woman in toxico-alcoholic epileptic treatment with VPA, showed a neutropenia possibly of secondary type which it was intended to change to LTG, following ...
Tópico(s): Pharmaceutical studies and practices
2000 - Viguera Publishers | Revista de Neurología
Salvador González-Pal, José M. Quintana, Reinaldo Fabelo, Luis López Rivero,
Epilepsy is a chronic illness which causes psychosocial problems in the patients affected. These disorders may be investigated by using the Washington Psychosocial Inventory (WPSI). We wish to show the variables which affect the WPSI most and also the changes seen in the results of this test and the control of seizures after treatment with lamotrigine for a year.Using the WPSI, we studied 70 patients in the epilepsy outpatient clinic of the Psychiatric Hospital in La Habana during the period February- ...
Tópico(s): Attention Deficit Hyperactivity Disorder
2000 - Viguera Publishers | Revista de Neurología
Rita Rodrigues, Pedro Amador, Leandro Rassi, Filipe Seixo, Leonor Parreira, Nuno Moreira Fonseca, Luís Soares,
The authors report the case of a 52-year-old woman with depressive syndrome, treated with lamotrigine for about five months, who went to the emergency department for atypical precordial pain. The electrocardiogram (ECG) revealed a 2-mm downsloping ST-segment elevation and negative T waves in V1 and V2. Due to suspicion of ST-elevation acute coronary syndrome, cardiac catheterization was performed, which revealed normal coronary arteries. The initial ECG was suggestive of type 1 Brugada pattern, but ...
Tópico(s): Ion channel regulation and function
2013 - Elsevier BV | Revista Portuguesa de Cardiologia
... potentes. El clobazam, la eslicarbazepina, el felbamato, la lamotrigina, la oxcarbazepina, el rufinamide, el topiramato, la vigabatrina ...
Tópico(s): Pharmaceutical studies and practices
2015 - Elsevier BV | Revista de Psiquiatría y Salud Mental (English Edition)
... potentes. El clobazam, la eslicarbazepina, el felbamato, la lamotrigina, la oxcarbazepina, la rufinamida, el topiramato, la vigabatrina ...
Tópico(s): Bipolar Disorder and Treatment
2015 - Elsevier BV | Revista de Psiquiatría y Salud Mental
Elena Fernández-Suárez, Rubén Villa-Estébanez, Alberto García-Martínez, José A Fidalgo-González, Ahmad Amer Zanabili Al-Sibbai, Javier Salas‐Puig,
... 5%. Farmacos mas prescritos: acido valproico, carbamacepina, fenitoina, lamotrigina y levetiracetam. Un 78,6% sin efectos secundarios. ...
Tópico(s): Pharmaceutical studies and practices
2015 - Viguera Publishers | Revista de Neurología
A. Alcántara-Montero, C.I. Sánchez-Carnerero,
... dolor neuropatico por las agencias reguladoras, como la lamotrigina, el topiramato o la oxcarbacepina, pero se utilizan ...
Tópico(s): Pain Management and Opioid Use
2016 - Viguera Publishers | Revista de Neurología
Meritxell Martínez Ferri, Pilar Peña Mayor, I Pérez López-Fraile, A. Escartin Siquier, M. Martin Moro, M. Forcadas Berdusan,
The prescription pattern of antiepileptic drugs (AEDs) during pregnancy is changing but to what extent this is occurring in Spain remains unknown. The efficacy of newer drugs for controlling seizures is a key issue and may have changed over the years as doctors gained familiarity with these drugs during pregnancy. To assess these 2 topics, we report the results from the Spanish EURAP register gathered over a 12-year period.After signing informed consent forms, patients were included in the register ...
Tópico(s): Epilepsy research and treatment
2016 - Elsevier BV | Neurología
B E Caviedes, J L Herranz, Rosa Arteaga, Juan A. Armijo,
Both vigabatrin (VGB) and lamotrigine (LTG) have been shown to be effective in the control of epileptic crises in double-blind randomized studies, as compared with placebos and as treatment in addition to the classical drugs.In this study we made a retrospective analysis of the evolution of 97 children aged from 6 months to 16 years with resistant epilepsy, to whose treatment either VGB or LTG were added.Frequency of the crises was reduced by > 50% in 54.7% of the children treated with VGB and in 57. ...
Tópico(s): Ion Transport and Channel Regulation
1999 - Viguera Publishers | Revista de Neurología
Jesús García-Jiménez, Marisol Álvarez-Fernández, Lidia Aguado-Bailón, Luís Gutiérrez-Rojas,
... síntomas mixtos y melancólicos y el uso de lamotrigina y quetiapina. Variabilidad en los resultados. Pocos estudios ...
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2017 - Elsevier BV | Revista de Psiquiatría y Salud Mental
A. Alcántara Montero, C.I. Sánchez Carnerero,
... el dolor neuropático por las agencias reguladoras, como lamotrigina o lacosamida, pero se utilizan en la práctica ...
Tópico(s): Pain Management and Opioid Use
2017 - Elsevier BV | Neurología