Karen K. Briggs, Ioanna K. Bolia,
... the damage caused by femoroacetabular impingement.2Kierkegaard S Langeskov-Christensen M Lund B et al.Pain, activities ... phase 1 trials had been done.2Kierkegaard S Langeskov-Christensen M Lund B et al.Pain, activities ...
Tópico(s): Musculoskeletal synovial abnormalities and treatments
2018 - Elsevier BV | The Lancet
Martin Langeskov‐Christensen, Daniel Langeskov-Christensen, Kristian Overgaard, Andreas Möller, Ulrik Dalgas,
Tópico(s): Cerebral Palsy and Movement Disorders
2014 - Elsevier BV | Journal of the Neurological Sciences
Martin Langeskov‐Christensen, Erika Franzén, Lars G. Hvid, Ulrik Dalgas,
Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or progression, while pharmacological symptomatic treatments have limited effects in certain domains and cause side effects. Identification of interventions that prevent, slow, halt or mitigate the disease is therefore pivotal. Exercise is safe and represents a cornerstone in PD rehabilitation, but exercise ...
Tópico(s): Botulinum Toxin and Related Neurological Disorders
2024 - BMJ | Journal of Neurology Neurosurgery & Psychiatry
Mads Gamborg, Lars G. Hvid, Cecilie Thrue, Sverker Johansson, Erika Franzén, Ulrik Dalgas, Martin Langeskov‐Christensen,
No studies have synthesized the literature regarding mechanical muscle function (ie, strength, power, rate of force development [RFD]) in people with Parkinson disease (PD). Here, we aimed to expand our understanding of mechanical muscle function in people with PD (PwPD) by systematically reviewing (1) the psychometric properties of isokinetic/isometric dynamometry in PD, (2) the literature comparing mechanical muscle function in PwPD with healthy controls (HC), and (3) reported associations between muscle ...
Tópico(s): Cerebral Palsy and Movement Disorders
2022 - Lippincott Williams & Wilkins | Journal of Neurologic Physical Therapy
Mads Gamborg, Lars G. Hvid, Ulrik Dalgas, Martin Langeskov‐Christensen,
In 2015, Uhrbrand et al. published the first review on Parkinson´s disease (PD) and exercise entirely based on randomized controlled trials (RCT) applying strict exercise definitions. The present review aimed to update the PD literature by assessing the effects of different intensive exercise modalities: resistance training (RT), endurance training (ET), and other intensive exercise modalities (OITM). An updated systematic literature search identified 33 new RCTs. Qualitative and quantitative analyses ...
Tópico(s): Muscle activation and electromyography studies
2022 - Wiley | Acta Neurologica Scandinavica
Martin Langeskov‐Christensen, Lars G. Hvid, Henrik Boye Jensen, Helle Hvilsted Nielsen, Thor Petersen, Egon Stenager, Ulrik Dalgas,
Objectives Fatigue and walking impairment are disabling symptoms of multiple sclerosis (MS). We investigated the effects of progressive aerobic exercise (PAE) on fatigue, walking, cardiorespiratory fitness (VO2max), and quality of life in people with MS (pwMS). Materials & Methods Randomized controlled trial (1:1 ratio, stratified by sex) with a 24-week crossover follow-up and intention-to-treat analysis. Allocation to an exercise (24 weeks of PAE followed by self-guided physical activity) and a waitlist ( ...
Tópico(s): Systemic Sclerosis and Related Diseases
2021 - Wiley | Acta Neurologica Scandinavica
Martin Langeskov‐Christensen, Lars G. Hvid, Mikkel Nygaard, Steffen Ringgaard, Henrik Boye Jensen, Helle Hvilsted Nielsen, Thor Petersen, Egon Stenager, Simon F. Eskildsen, Ulrik Dalgas,
To determine whether 24 weeks of high-intensity progressive aerobic exercise (PAE) affects brain MRI measures in people with multiple sclerosis (MS).We conducted a randomized, controlled, phase 2 trial (with a crossover follow-up) including an exercise group (supervised PAE followed by self-guided physical activity) and a waitlist group (habitual lifestyle followed by supervised PAE). Mildly to severely impaired patients with MS aged 18-65 years were randomized (1:1). The primary outcome was percentage ...
Tópico(s): Systemic Sclerosis and Related Diseases
2020 - Lippincott Williams & Wilkins | Neurology
Martin Langeskov‐Christensen, Lars G. Hvid, Henrik Boye Jensen, Helle Hvilsted Nielsen, Thor Petersen, Egon Stenager, Päivi Hämäläinen, Ulrik Dalgas,
Background Cognitive impairment is highly prevalent in multiple sclerosis (MS). Progressive aerobic exercise (PAE) represents a promising approach toward preservation or even improvement of cognitive performance in people with MS (pwMS). Objective To investigate the effects of PAE on the cognitive domains of information processing, learning and memory, and verbal fluency in pwMS. Methods This randomized controlled trial included an exercise ( n = 43, 24 weeks of supervised PAE, followed by self-guided ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2020 - SAGE Publishing | Multiple Sclerosis Journal
Ulrik Dalgas, Martin Langeskov‐Christensen, Egon Stenager, Morten Riemenschneider, Lars G. Hvid,
Tópico(s): Amyotrophic Lateral Sclerosis Research
2019 - Springer Science+Business Media | Current Neurology and Neuroscience Reports
Ulrik Dalgas, Martin Langeskov‐Christensen, Anders Guldhammer Skjerbæk, Ellen Jensen, Ilse Baert, Anders Romberg, Carme Santoyo-Medina, Benoit Gebara, Benoît Maertens de Noordhout, Kathy Knuts, F. Béthoux, Kamila Řasová, Deborah Severijns, Bo Martin Bibby, Alon Kalron, Bryan A. Norman, Fanny Van Geel, Inez Wens, Peter Feys,
The relationship between fatigue impact and walking capacity and perceived ability in patients with multiple sclerosis (MS) is inconclusive in the existing literature. A better understanding might guide new treatment avenues for fatigue and/or walking capacity in patients with MS.To investigate the relationship between the subjective impact of fatigue and objective walking capacity as well as subjective walking ability in MS patients.A cross-sectional multicenter study design was applied. Ambulatory ...
Tópico(s): Powdery Mildew Fungal Diseases
2018 - Elsevier BV | Journal of the Neurological Sciences
Daniel Langeskov-Christensen, Peter Feys, Ilse Baert, Morten Riemenschneider, Egon Stenager, Ulrik Dalgas,
Background The severity of walking impairment in persons with multiple sclerosis (pwMS) at different levels on the expanded disability status scale (EDSS) is unclear. Furthermore, it is unclear if the EDSS is differently related to performed- and perceived walking capacity tests. Aims To quantify walking impairment and perceived impact of MS on walking according to EDSS scores and to examine the relations between these parameters in pwMS. Methods EDSS was collected by neurologists and walking was ...
Tópico(s): Effects of Vibration on Health
2017 - Elsevier BV | Journal of the Neurological Sciences
Martin Langeskov‐Christensen, Etienne J. Bisson, Marcia Finlayson, Ulrik Dalgas,
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2017 - Elsevier BV | Journal of the Neurological Sciences
Signe Kierkegaard, Martin Langeskov‐Christensen, Bent Lund, Florian D. Naal, Inger Mechlenburg, Ulrik Dalgas, Nicola C. Casartelli,
Aim To investigate pain, activities of daily living (ADL) function, sport function, quality of life and satisfaction at different time points after hip arthroscopy in patients with femoroacetabular impingement (FAI). Design Systematic review with meta-analysis. Weighted mean differences between preoperative and postoperative outcomes were calculated and used for meta-analysis. Data sources EMBASE, MEDLINE, SportsDiscus, CINAHL, Cochrane Library, and PEDro. Eligibility criteria for selecting studies ...
Tópico(s): Shoulder Injury and Treatment
2016 - BMJ | British Journal of Sports Medicine
Martin Langeskov‐Christensen, Martin Heine, Gert Kwakkel, Ulrik Dalgas,
Tópico(s): Fungal Infections and Studies
2015 - Springer Science+Business Media | Sports Medicine
Tue Kjølhede, Kristian Vissing, Daniel Langeskov-Christensen, Egon Stenager, Thor Petersen, Ulrik Dalgas,
Background Maximal muscle strength has been shown to be an important predictor of functional capacity for persons with multiple sclerosis (PwMS). Another muscle strength parameter known to be important for functional capacity in other patient groups is rate of force development (RFD) in knee extensors and flexors. This has not been investigated for PwMS. Thus, the purpose of this study was to investigate the relationship between RFD and maximal muscle strength of knee extensors and flexors and measures ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2015 - Elsevier BV | Multiple Sclerosis and Related Disorders
Martin Heine, Inez Wens, Martin Langeskov‐Christensen, Olaf Verschuren, Bert O. Eijnde, Gert Kwakkel, Ulrik Dalgas,
In persons with MS (pwMS), a lower cardiopulmonary fitness has been associated with a higher risk for secondary disorders, decreased functional capacity, symptom worsening and reduced health-related quality of life.To investigate the association between disease severity and cardiopulmonary fitness.Data from cardiopulmonary exercise tests, previously conducted in three different countries, were pooled. The association between disease severity (Expanded Disability Status Scale (EDSS)) and cardiopulmonary ...
Tópico(s): Long-Term Effects of COVID-19
2015 - SAGE Publishing | Multiple Sclerosis Journal
M. Albrechtsen, Martin Langeskov‐Christensen, M.L.K. Jørgensen, Ulrik Dalgas, Mette Hansen,
Background Diet may have immunomodulatory effects in persons with multiple sclerosis (PwMS) and studies suggest that diet may be considered a complementary treatment to control the progression of the disease. The role of nutrition in MS and related symptoms have been reported by several studies but remains controversial. Objective To explore the association between dietary intake and physical capacity and fatigue in PwMS. Methods An explorative cross-sectional pilot study was conducted, in which ...
Tópico(s): Fibromyalgia and Chronic Fatigue Syndrome Research
2019 - Elsevier BV | Multiple Sclerosis and Related Disorders
Martin Langeskov‐Christensen, Søren Eskildsen, Egon Stenager, Henrik Boye Jensen, Helle Hvilsted Nielsen, Thor Petersen, Lars G. Hvid, Päivi Hämäläinen, Lisbet Marstrand, Ulrik Dalgas,
(1) Background: Cognitive impairment is highly prevalent in multiple sclerosis (MS). Staying physically fit may be associated with preservation of cognitive performance in persons with MS (pwMS); (2) Objective: To investigate the association between aerobic capacity and the cognitive domains of information processing, learning and memory, and verbal fluency as well as single and composite z-scores of the Brief Repeatable Battery of Neuropsychological tests (BRBNT) in pwMS; (3) Methods: All subjects first ...
Tópico(s): Autoimmune and Inflammatory Disorders Research
2018 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Cecilie Thrue, Lars G. Hvid, Mads Gamborg, Helen Dawes, Ulrik Dalgas, Martin Langeskov‐Christensen,
Purpose To systematically review studies assessing (1) psychometric properties of the maximal oxygen uptake (VO2max) test in PD, (2) VO2max levels in persons with PD (pwPD) compared to healthy controls (HCs), and (3) reported VO2max associations in PD.Materials and methods Six databases were searched. Descriptive data synthesis was used to summarize psychometric properties and reported VO2max associations. The VO2max means and test end-criteria were calculated using linear mixed models. Simple linear ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2022 - Informa | Disability and Rehabilitation
Marit Lea Schlagheck, Jens Bansi, Martin Langeskov‐Christensen, Philipp Zimmer, Lars G. Hvid,
Objectives Cardiorespiratory fitness (measured as peak oxygen uptake; V̇O2peak) is a well-established health predictor in the general population and in persons with multiple sclerosis (pwMS). We aimed to investigate differences in V̇O2peak between age groups and the prevalence of V̇O2peak impairments across the adult lifespan in pwMS compared to age- and sex-matched healthy controls (HC). Design Cross-sectional study. Methods Data from 469 pwMS (EDSS range 1.0–7.0), who carried out graded cardiopulmonary ...
Tópico(s): Balance, Gait, and Falls Prevention
2023 - Elsevier BV | Journal of science and medicine in sport
Emilie K. Langeskov, Kim Kristensen,
Semaglutide is a glucagon-like-peptide-1 (GLP-1) analogue marketed for once-weekly subcutaneous administration for type 2 diabetes mellitus. Like other long-acting GLP-1 analogues, semaglutide reduces gastric emptying and, potentially, alters the rate of absorption of orally co-administered drugs. The objective of the current analysis was to evaluate the effects on the gastric emptying rate caused by semaglutide on pharmacokinetic model parameters of paracetamol and atorvastatin in healthy subjects. ...
Tópico(s): Drug Transport and Resistance Mechanisms
2022 - Wiley | Pharmacology Research & Perspectives
Henrik Thrane, Arne Juottijärvi,
A hoard was discovered at Mariesminde near the centre of the Danish island Funen in 2003 during trial excavations. A pot containing 27 bronzes was later excavated in the museum laboratory. The bronzes were stacked disorderly, with a large piece of sheet bronze at the bottom. The objects consisted of broken rings, several so-called ‘Hohlwulstringe’ or hollow rings, a socketed axe, plus 13 casting cakes and three casting runners. No less than four rings are types new to Scandinavia and reflect connections ...
2020 - Wiley | Acta Archaeologica
Frederik Bonde-Jensen, Ulrik Dalgas, John Brincks, Martin Langeskov‐Christensen,
Direct whole body assessment of maximal oxygen consumption (VO2-max test) is considered the gold standard when assessing cardiorespiratory fitness (VO2-max) in healthy people. VO2-max is also an important health and performance indicator for persons with Parkinson's disease (pwPD) and is often used when prescribing exercise and evaluating aerobic exercise interventions. However, no study has examined the content validity of the VO2-max test in pwPD as well as the test-retest reliability (i.e., day-to- ...
Tópico(s): Balance, Gait, and Falls Prevention
2023 - Elsevier BV | Parkinsonism & Related Disorders
Mikkel Nygaard, Martin Langeskov‐Christensen, Ulrik Dalgas, Simon F. Eskildsen,
Tópico(s): MRI in cancer diagnosis
2021 - Springer Science+Business Media | Journal of Neurology
Martin Langeskov‐Christensen, Tue Kjølhede, Egon Stenager, Henrik Boye Jensen, Ulrik Dalgas,
Flu-like symptoms (FLS) are common side effects of interferon beta (IFNß) treatment, and may affect the willingness to initiate therapy, the long-term acceptability, and the adherence to the treatment. Case reports suggest that aerobic exercise is able to markedly reduce FLS following IFNß-1a injections in persons with multiple sclerosis (PwMS).To test the hypothesis that aerobic exercise can alleviate FLS following IFNß-1a injections in PwMS, and secondarily to examine whether or not fluctuations ...
Tópico(s): Immune Cell Function and Interaction
2016 - Elsevier BV | Journal of the Neurological Sciences
Martin Langeskov‐Christensen, Søren Eskildsen, Egon Stenager, Henrik Boye Jensen, Helle Hvilsted Nielsen, Thor Petersen, Lars G. Hvid, Päivi Hämäläinen, Lisbet Marstrand, Ulrik Dalgas,
The authors wish to make the following corrections to this paper [...]
Tópico(s): Long-Term Effects of COVID-19
2019 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Lars G. Hvid, Martin Langeskov‐Christensen, Egon Stenager, Ulrik Dalgas,
... paradigm shift in our 2019 review.5Dalgas U Langeskov-Christensen M Stenager E Riemenschneider M Hvid LG ... paradigm shift in our 2019 review.5Dalgas U Langeskov-Christensen M Stenager E Riemenschneider M Hvid LG ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2022 - Elsevier BV | The Lancet Neurology
Frederik Bonde-Jensen, Ulrik Dalgas, Martin Langeskov‐Christensen,
IntroductionIncreased physical activity (PA) may slow Parkinson's disease (PD), progression. Associations between markers of PA and PD severity could justify further, studies evaluating interventions increasing PA levels in PD. The objectives of the, present study were to assess associations between PA, cardiorespiratory fitness (VO2-, max), and muscle peak power and measures of the Movement Disorder Societysponsored, revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), the Parkinson' ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2024 - Elsevier BV | Journal of the Neurological Sciences
I Made Aryantha Anthara, Emilie Kirstine Langeskov Salim,
Abstract The purpose of this research is to find out the opportunity to move from a coffee brand to another coffee brand in a certain period of time and then, make a prediction of the chances of further coffee transfer until the steady state condition is obtained. This research is motivated by the phenomenon of selling three brands of coffee in one of the stalls in the Garut area. The method that used in this research was “Markov Theory” in which the time span used was the number of sales of each ...
Tópico(s): Health, Technology, Consumer Behavior
2019 - IOP Publishing | IOP Conference Series Materials Science and Engineering
Anoire El attari, Chaimae Bouchala, Emilie Kirstine Langeskov Salim, Abderrahman Tenkoul,
During the COVID-19 pandemic, journalists all over the world were tasked with the mission of disseminating information and providing answers to the public opinion. This paper aims at exploring the challenges that have influenced Moroccan journalists using a comparative study. Through a thematic analysis of N=30 interviews with journalists from public and private media, this study aims to study the differences in the challenges during the coverage of the Covid-19 pandemic. The results of this study ...
Tópico(s): COVID-19 Pandemic Impacts
2024 - | Studies in Media and Communication