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Jornais Acesso aberto

L. Wulff, M. A. Denaeyer, M. J. -B. Tondeur, M. Paul Roy,

... De Révélateurs Énergiques, Moyen De Blanchir La Gomme Laque Blonde Pour Le Vernis Négatif. Review: Société Francaise ...

0000 - Gale Group | NCCO Photography

Artigo

A. I. G. McLaughlin, P. L. Bidstrup, M. Konstam,

... dames provenaient d'établissements utilisant (i) uniquement des laques à base de gomme laque, (ii) uniquement des laques à base de polyvinylpyrolidone (PVP) et (iii) des laques des deux types susmentionnés. Dans le cas (i) ... des sujets avaient été en contact avec la laque depuis plus de 6 ans; dans le cas ( ... dans la thésaurose. La majorité des particules de laque, provenant aussi bien des vaporisateurs manuels que des ... de particules en fonction de la quantité de laque employée et des conditions de ventilation. Dans deux ...

Tópico(s): Occupational exposure and asthma

1963 - Elsevier BV | Food and Cosmetics Toxicology

Jornais Acesso aberto

R. Namias, C. W. Butler, Ch. Puttemans, T. Thorne Backer, Ch. Puttemans, J. Vanderborght, Robert Vander Haeghen, L. Morisseaux, Charles Mendel,

... D'impression Au Phosphate Et À La Gomme Laque, Section De Liége Séance Du 8 Octobre 1909, ...

1909 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Ken Sutherland,

... widespread than previously thought. Résumé «Les vernis gomme‐laque blanche des peintures: caractérisation et études de cas» ... au point pour l'identification de la gomme‐laque blanchie en utilisant la chromatographie en phase gazeuse ... masse sur des échantillons de référence de gomme‐laque blanchie et non blanchie obtenus auprès de fournisseurs ... avec succès à l'identification des vernis gommes‐laques blanches («white shellac» ou «bleached shellac») sur des ... des Beaux Arts de Philadelphie (USA). La gomme‐laque blanche a aussi été identifiée sur un échantillon ...

Tópico(s): Building materials and conservation

2010 - Taylor & Francis | Journal of the Institute of Conservation

Jornais Acesso aberto

P Morris, Michael Moorcock, Mike Long, Will Ellsworth-Jones, Philip Norman, Elsie Marshall, Rob Hughes, Jean Robertson Travel Editor, Nicaragua, Tony Avirgan, Peter Marson, Francis Wyndham, David Basnett, Ian Hodgson, Nairobi, Margaret Norton Briggs, Peter Calvocoressi, Berry Ritchie, Graham Rose, Geoffrey Tucker, David Fletcher, Antony Terry, Ronald Blythe, Colin New, Anne Redmon, Cal McCrystal, Jason Tomas, Brian Quinn, Mark Jackson, Dalbert Hallenstein Milan, Majorie Wallace, Philip Oakes, John Power Labour prospective, Renate Kohler, Henry Brandon, Maurice Barnfather, Joseph Sebag, Richard Milner, Bernard Levin, Mark Ottaway, Geoff Gower, Craig Raine, David Dougill, Richard J Manville, Joe Irving, N G Wilson, John Clarke, Susannah Clapp, Charles Reiss, Ivor Tilney, Jad Adams, Sarah Meysey-Thompson, David Coward, Kenneth Fleet Editor Business News, Peter Watson, Peter Rodgers Energy Editor, David Cairns, John Ballantine, Joan Lock, Caroline Darby, David Blundy, Carol Price, Geoff Whitten, Peter Kellner, Robert Troop, James Jarche, Malcolm Crawford Economics Editor, Patrick Forman, Johnny Rotten, Woodrow Wyatt, Roger Eglin, Michael Nimmo, Michael Howard, Mrs Agnes Donnellon, Boris Schapiro, Robert Stoten, Robert Blake, Sir Robert Mark, Philip Harbottle, Mrs E W Taylor, Brian Jackman, Judith Jackson, Richard Girling, John Fryer Labour Correspondent, MacMillar, Nicholas Royston TV director, John Hopkins, Russell Kerr, Eric Marsden, Stephen Wood, David Robson, Hugo Young Political Editor, Bryan Silcock, Gareth Huw Davies, Eric Jacobs Labour Editor, Peter Scott, Joan Asquith, Arnold Legh, Elaine Potter, Peter Stothard, Michael Pye, Martin Webster, Charles Harrison, Muir, Jeremy Brooks, Alan Brien, Russell Davies, Alfred Morris, Gwen Nuttall, Herbie Stewert, Jane Henderson, F S Cole Retired Aa man, Patrick Rowley, Dylan Thomas, Dilys Powell, John Bell City Editor, Brough Scott, Tony Rocca, Oliver Gillie Medical Correspondent, Elkan Allan, Kenneth Fleet, Gordon Burn, Dar es Salaam, M Mohsin, Dudley Doust, Ian Nairn, Quentin Crewe, Maurice Cranston, Benjamin Pogrund, Peter Wilby, Tony Allaway, Ian Jack, Matthew Hoffman, Stephen Fay, John Thirsk, Peter Clarke, Robert Kennedy, Richard Burnell, Anthony Mascarenhas, Bernard D Nossiter London Correspondent, Andrew Stephen, Michael Moynihan, Brian Glanville, Michael Booth, Anthony Holden, Paddy French, Michael Roberts, Michael Green, Peter James, Michael Jones Political Correspondent, Linda Melvern, Marina Vaizey, John Campbell, M S Kalindjian, Alan Minter, Sir John Methven, Philip Jacobson, Patience Wheatcroft, Dr Frank A Heller, Jon Connell, Muriel Bowen,

... Killed Great Tew Prettiest Village in England The Laque Rough from Waterman Asbach Brandy SieMatic UK Ltd. ...

1978 - Gale Group | Sunday Times HA GDA

Artigo

Albert Selva-O’Callaghan, Dolors Rodríguez-Pardo, Lluis Sanchez-Sitjes, Laia Matas-Pericas, Roser Soláns-Laqué, Josep Angel Bosch-Gil, Miguel Vilardell-Tarr�s,

... SpainSearch for more papers by this authorRoser Solans-Laque MD, PhD, Roser Solans-Laque MD, PhD Vall d'Hebron General Hospital, Barcelona, ... SpainSearch for more papers by this authorRoser Solans-Laque MD, PhD, Roser Solans-Laque MD, PhD Vall d'Hebron General Hospital, Barcelona, ...

Tópico(s): Salivary Gland Disorders and Functions

1999 - Wiley | Arthritis & Rheumatism

Artigo Revisado por pares

Patricia Roger, Inès Villela-Petit, Solène Vandroy,

... nous avions identifié un colorant rouge utilisé en laque qui ne correspondait pas à ceux Ie plus ... la fabrication en laboratoire de. différents échantillons de laques de brésil. Chaque laque, appliquée en glacis ou en couche opaque, a ...

Tópico(s): Conservation Techniques and Studies

2003 - Taylor & Francis | Studies in Conservation

Jornais Acesso aberto

M. A. Taylor, M. Stillman, M. Léon Vidal,

... Par M. Stillman, Communications Positifs a La Gomme Laque, Polychromie Photographique; Par M. Léon Vidal, Secrétaire De ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Marcel Pourbaix,

... Traud, ainsi que l'exposé de F. L. LaQue sur les relations entre la recherche électrochimique et ... W. Traud and the statement of F. L. LaQue on the links connecting electrochemical research and corrosion ... W. Traud und die Feststellung von F. L. LaQue über die Verbindungen zwischen elektrochemischer Forschung und Korrosionsforschung ...

Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals

1974 - Elsevier BV | Corrosion Science

Jornais Acesso aberto

E. Egasse, A. Dietrich, Henry Labbé, Fabien Bénardeau, M. Paul Roy, E. Schmidt, G. Rongier,

... Lumière Au Magnésium, Moyen De Blanchir La Gomme Laque Blonde Pour Le Vernis Négatif, Premiére Exposition Italienne ...

1887 - Gale Group | NCCO Photography

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gabriela Hernández‐Molina, Belchin Kostov, Pilar Brito‐Zerón, Arjan Vissink, Thomas Mandl, Anneline C. Hinrichs, Luca Quartuccio, Chiara Baldini, Raphaèle Séror, Antónia Szántó, David Isenberg, Roberto Gerli, Gunnel Nordmark, Astrid Rasmussen, Roser Soláns-Laqué, Benedikt Hofauer, D. Sène, Sandra Gofinet Pasoto, Maureen Rischmueller, Sonja Praprotnik, Tamer A. Gheita, Debashish Danda, Berkan Armağan, Yasunori Suzuki, Valéria Valim, Valérie Devauchelle‐Pensec, Soledad Retamozo, Marika Kvarnström, Agata Sebastian, Fabiola Atzeni, Roberto Giacomelli, Steven E. Carsons, Seung‐Ki Kwok, Hideki Nakamura, Virgínia Fernandes Moça Trevisani, Alejandra Flores-Chávez, Xavier Mariette, Manuel Ramos‐Casals, Pilar Brito‐Zerón, Alejandra Flores-Chávez, Manuel Ramos‐Casals, Ildikó Fanny Horváth, Antónia Szántó, Tünde Tarr, F Ng, Astrid Rasmussen, Darise Farris, Dong Xu, Yan Zhang, Xingyuan Li, Baoshan Xu, Chiara Baldini, Stefano Bombardieri, Thomas Mandl, Peter Olsson, Roberta Priori, Federico Giardina, Raffaella Izzo, Raphaèle Séror, Xavier Mariette, Jacques‐Eric Gottenberg, Aike A. Kruize, Anneline C. Hinrichs, Hendrika Bootsma, Arjan Vissink, Debashish Danda, Pulukool Sandhya, Gabriela Hernández‐Molina, Jorge Sánchez‐Guerrero, Berkan Armağan, Levent Kılıç, Umut Kalyoncu, Luca Quartuccio, Saviana Gandolfo, Salvatore De Vita, Sonja Praprotnik, Agata Sebastian, Piotr Wiland, Roberto Gerli, Elena Bartoloni, S-K Kwok, So Hyun Park, Marika Kvarnström, Marie Wahren‐Herlenius, Maureen Rischmueller, Sarah Downie‐Doyle, Roser Soláns-Laqué, D. Sène, Sandra Gofinet Pasoto, Yasunori Suzuki, M Kawano, David Isenberg, Gunnel Nordmark, Valéria Valim, Hideki Nakamura, Toshimasa Shimizu, Shinya Nishihata, Takashi Nakamura, Yukinori Takagi, Virgínia Fernandes Moça Trevisani, Soledad Retamozo, Benedikt Hofauer, Andreas Knopf, G. Fraile, Roberto Giacomelli, Valérie Devauchelle‐Pensec, Alain Saraux, Stefano Bombardieri, Elisa Astorri, Fabiola Atzeni, Daniel Hammenfors, Johan G. Brun, Steven E. Carsons, B. Maure Noia, A. Filgueira, Tamer A. Gheita, Isabel Sánchez Berná, Miguel López-Dupla, R. Rojas, A M Febrer Nafria, Jérôme Morel, Eva Fonseca Aizpuru, Samuel Seoane, Pilar Brito‐Zerón, C. Morcillo, Sheila Melchor Díaz, Patrícia Carreira, Cristina Vollenveider, Marcos Vázquez, P Ericka Díaz Cuiza, B E Herrera, Sandra Consani, A Comotto, Borja de Miguel Campo, Belchin Kostov, Antoni Sisó‐Almirall, Belchin Kostov, Nihan Acar‐Denizli,

To characterize 414 patients with primary SS who developed haematological malignancies and to analyse how the main SS- and lymphoma-related features can modify the presentation patterns and outcomes.By January 2021, the Big Data Sjögren Project Consortium database included 11 966 patients fulfilling the 2002/2016 classification criteria. Haematological malignancies diagnosed according to the World Health Organization (WHO) classification were retrospectively identified.There were 414 patients (355 ...

Tópico(s): Salivary Gland Tumors Diagnosis and Treatment

2022 - Oxford University Press | Lara D. Veeken

Jornais Acesso aberto

Ernest Boivin, J. B. B. Wellington, A. Nicot,

... Épreuves Instantanées, Réactif Concentré D'eastman Pour Développer, Laque (Vernis) Pour Plaque a La Gélatine, Procédé D' ...

1888 - Gale Group | NCCO Photography

Artigo Revisado por pares

Liliane Masschelein-Kleiner, J. Heylen,

... identification des matières colorantes naturelles utilisées dans les laques rouges anciennes.Les spectroscopies d'absorption dans l' ...

Tópico(s): Building materials and conservation

1968 - Taylor & Francis | Studies in Conservation

Jornais Acesso aberto

M. Sebastian Davis, M. Keene, M. Kaiser, M. H. Vogel, M. Gaudin, E. Saint-Edme, M. Arthur Taylor, M. Sarony, C. Schnaitter,

... albumine, Préparation Du Papier Positif a La Gomme Laque, Sur La Solubilité Des Iodures Dans Le Collodion, ...

1866 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Stanislas Grassin‐Delyle, B Mathieu, Emuri Abé, Jean‐Claude Alvarez,

... amphétamines) et des benzodiazépines dans du sang total laqué par l'analyseur Evidence Investigator. 128 échantillons contenant ...

Tópico(s): Biosensors and Analytical Detection

2008 - Elsevier BV | Annales de Toxicologie Analytique

Artigo Revisado por pares

Fernando Schütz, M. Bonfanti, Christophe Champod,

... laiton galvanisé au nickel, aluminium, cuivre et fer laqué), ceci en comparaison avec une technique concurrente: la ... réaction. Les douilles en aluminium et en fer laqué restent des surfaces problématiques pour détecter des traces ...

Tópico(s): Additive Manufacturing Materials and Processes

2000 - Taylor & Francis | Canadian Society of Forensic Science Journal

Artigo

H. E. Searle, F. L. LaQue, R. H. Dohrow,

... of Wines for MetalsH. E. Searle, F. L. LaQue, and R. H. DohrowCite this: Ind. Eng. Chem. ...

Tópico(s): Analytical chemistry methods development

1934 - American Chemical Society | Industrial & Engineering Chemistry

Artigo Revisado por pares

Catherine Coueignoux,

... after treatment.TITRE—Le nettoyage aqueux de la laque orientale endommaǵee par la lumìere: une ´etude de ... est souvent hasardeux et problématique de nettoyer la laque orientale endommagée par la lumière. Bien que l' ... elle peut aussi interagir avec les surfaces de laque dégradée. Cette recherche a démontré que le pH ... cas sur le nettoyage d'une surface en laque rouge déjà dégradée, qui avait été endommagée par ... sans retirer aucun produit de dégradation de la laque. Un examen sous microscope de coupes stratigraphiques montre ...

Tópico(s): Building materials and conservation

2009 - Routledge | Journal of the American Institute for Conservation

Artigo Revisado por pares

M. C. Festou, J. Lecacheux, J. L. Kohl, Thérèse Encrenaz, J. Baudrand, M. Combes, R. Despiau, R. Laques, P. Laques, O. Le Fèvre, J. P. Lemonnier, G. Lelièvre, G. Mathez, M. Pierre, J. L. Vidal,

Enregistrement de l'activite de la comete de Halley entre novembre 1984 et mars 1985 depuis quatre sites d'observation differents

Tópico(s): Solar and Space Plasma Dynamics

1986 - EDP Sciences | Astronomy and Astrophysics

Artigo Acesso aberto Revisado por pares

José Loureiro-Amigo, Clara Franco‐Jarava, Janire Perurena-Prieto, Carlos Palacio, Fernando Martínez‐Valle, Roser Soláns-Laqué,

Objective.To investigate the utility of serum BAFF, CXCL13, as biomarkers of disease activity in primary Sjögren's syndrome (pSS), their relationship with lymphocyte subpopulations and their accuracy to discriminate pSS from Sicca syndrome.Methods.We conducted an observational study on 66 pSS patients and 48 controls (25 with Sicca syndrome and 23 healthy volunteers).Serum levels of BAFF, IL-17 A/F, IL-18, IL-21, IL-22, CXCL13, TNF-R2 and PD-L2 were measured using a multiplex immunoassay.Lymphocyte ...

Tópico(s): Lymphatic System and Diseases

2021 - Springer Vienna | Clinical and Experimental Rheumatology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Soledad Retamozo, Nihan Acar‐Denizli, Ildikó Fanny Horváth, Wan‐Fai Ng, Astrid Rasmussen, Dong Xu, Xiaomei Li, Chiara Baldini, Peter Olsson, Roberta Priori, Raphaèle Séror, Jacques-Éric Gottenberg, Aike A. Kruize, Gabriela Hernández‐Molina, Arjan Vissink, Pulukool Sandhya, Berkan Armağan, Luca Quartuccio, Agata Sebastian, Sonja Praprotnik, Elena Bartoloni, Seung‐Ki Kwok, Marika Kvarnström, Maureen Rischmueller, Roser Soláns-Laqué, D. Sène, Sandra Gofinet Pasoto, Yasunori Suzuki, David Isenberg, Valéria Valim, Gunnel Nordmark, Hideki Nakamura, Virgínia Fernandes Moça Trevisani, Benedikt Hofauer, Antoni Sisó‐Almirall, Roberto Giacomelli, Valérie Devauchelle‐Pensec, Stefano Bombardieri, Fabiola Atzeni, Daniel Hammenfors, B. Maure, Steven E. Carsons, Tamer A. Gheita, Isabel Sánchez‐Berná, Miguel López-Dupla, Jacques Morel, Nevsun İnanç, Eva Fonseca‐Aizpuru, C. Morcillo, Cristina Vollenweider, Sheila Melchor, Marcos Vázquez, Ericka Díaz-Cuiza, Sandra Consani-Fernández, Borja De-Miguel-Campo, Antónia Szántó, Stefano Bombardieri, Angelica Gattamelata, Anneline C. Hinrichs, Jorge Sánchez‐Guerrero, Debashish Danda, Levent Kılıç, Salvatore De Vita, Piotr Wiland, Roberto Gerli, Sung‐Hwan Park, Marie Wahren‐Herlenius, Hendrika Bootsma, Xavier Mariette, Manuel Ramos‐Casals, Pilar Brito‐Zerón,

To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS).By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagnosis was defined as the time when the attending physician confirmed fulfilment of the criteria. Patients were clustered according ...

Tópico(s): Inflammasome and immune disorders

2021 - Springer Vienna | Clinical and Experimental Rheumatology

Artigo Revisado por pares

Ryan A. Rava, Samantha Seymour, Meredith E. LaQue, B Peterson, Kenneth V. Snyder, Maxim Mokin, Muhammad Waqas, Yiemeng Hoi, Jason M. Davies, Elad I. Levy, Adnan H. Siddiqui, Ciprian N. Ionita,

Immediate and accurate detection of intracranial hemorrhages (ICHs) is essential to provide a good clinical outcome for patients with ICH. Artificial intelligence has the potential to provide this, but the assessment of these methods needs to be investigated in depth. This study aimed to assess the ability of Canon's AUTOStroke Solution ICH detection algorithm to accurately identify patients both with and without ICHs present. Data from 200 ICH and 102 non-ICH patients who presented with stroke-like ...

Tópico(s): Neurosurgical Procedures and Complications

2021 - Elsevier BV | World Neurosurgery

Artigo Revisado por pares

Eloi García-Vives, José F. Rodríguez‐Palomares, Len Harty, Roser Soláns-Laqué, David Jayne,

To define the pattern of cardiac involvement in eosinophilic granulomatosis and polyangiitis (EGPA) and propose an algorithm for heart disease screening.This was a retrospective study of EGPA patients attending a specialized vasculitis clinic (1989-2016). Clinical characteristics and cardiovascular evaluation (CE) results (serum troponin, ECG, echocardiography and cardiac magnetic resonance) were collected and compared according to symptoms and inflammatory cardiac disease (ICD).A total of 131 EGPA patients ...

Tópico(s): Sarcoidosis and Beryllium Toxicity Research

2021 - Oxford University Press | Lara D. Veeken

Artigo Revisado por pares

Matt A. Limmer, Abby E. Evans, Angelia L. Seyfferth,

The roots of aquatic plants, including rice, release oxygen into the subsurface, precipitating reduced metals, such as iron (Fe) and manganese (Mn), as plaques that form on the surface of the roots. These plaques are a unique habitat for microorganisms and a hotspot for biogeochemical cycling, including the toxic trace metalloid arsenic (As). However, studying plaque deposition and mineral composition in this spatially and temporally heterogeneous environment is challenging, particularly in situ. Here, ...

Tópico(s): Geochemistry and Elemental Analysis

2020 - American Chemical Society | Environmental Science & Technology

Artigo Acesso aberto Revisado por pares

Amanda Laque, Genna L. De Ness, Grant E. Wagner, Hermina Nedelescu, Ayla Carroll, Debbie D. Watry, Tony M. Kerr, Eisuke Koya, Bruce T. Hope, Friedbert Weiss, Gregory I. Elmer, Nobuyoshi Suto,

Abstract Drug addiction is a chronic relapsing disorder of compulsive drug use. Studies of the neurobehavioral factors that promote drug relapse have yet to produce an effective treatment. Here we take a different approach and examine the factors that suppress—rather than promote—relapse. Adapting Pavlovian procedures to suppress operant drug response, we determined the anti-relapse action of environmental cues that signal drug omission (unavailability) in rats. Under laboratory conditions linked ...

Tópico(s): Memory and Neural Mechanisms

2019 - Nature Portfolio | Nature Communications

Artigo Revisado por pares

Roser Soláns-Laqué, Mónica Rodríguez‐Carballeira, Juan José Ríos Blanco, G. Fraile, Luis Sáez‐Comet, Aleida Martínez Zapico, Begoña Frutos, Xavier Solanich, Eva Fonseca‐Aizpuru, Francisco Pasquau‐Liaño, Mónica Zamora, J. Oristrell, P. Fanlo, Miguel López-Dupla, M. Abdilla, Isabel Sánchez, B. Sopeña, María Jesús Castillo, Isabel Perales, José Luis Callejas‐Rubio,

Objective To compare the accuracy of the Birmingham Vasculitis Activity Score ( BVAS ), version 3, and the Five Factor Score ( FFS ), version 1996 and version 2009, to assess survival in antineutrophil cytoplasmic antibody–associated vasculitis ( AAV ). Methods A total of 550 patients with AAV (41.1% with granulomatosis with polyangiitis, 37.3% with microscopic polyangiitis, and 21.6% with eosinophilic granulomatosis with polyangiitis), diagnosed between 1990 and 2016, were analyzed. Receiver operating characteristic ( ...

Tópico(s): Urticaria and Related Conditions

2019 - Wiley | Arthritis Care & Research

Artigo Revisado por pares

Jaume Mestre-Torres, M. Simó-Perdigó, Fernando Martínez‐Valle, I. Navales, José Loureiro-Amigo, Roser Soláns-Laqué,

Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes

2019 - Springer Science+Business Media | European Journal of Nuclear Medicine and Molecular Imaging

Artigo Acesso aberto Revisado por pares

Mark D Lyttle, Naomi Rainford, Carrol Gamble, Shrouk Messahel, Amy Humphreys, Helen Hickey, Kerry Woolfall, Louise Roper, Joanne Noblet, Elizabeth D. Lee, Sarah Potter, Paul Tate, Anand Iyer, Vicki Evans, Richard Appleton, Matthew Pereira, Susie Hardwick, Shrouk Messahel, Joanne Noblet, Elizabeth D Lee, Rachel Greenwood-Bibby, M S Buchanan, Lucy Lewis, Sharon Hughes, Stuart Hartshorn, Louise Rogers, Juliet Hopkins, Mark D Lyttle, Daphin Fernandez, Sarah Potter, Holly R Lavigne-Smith, Phoebe Moulsdale, Alice Smith, Tracey Bingham, James N. Ross, Natasha Ramsey, Jo Hacking, Niall Mullen, Paul Corrigan, S Prudhoe, Hani Faza, Gisela Robinson, Rachel Sunley, Coral Smith, Vanessa Unsworth, John Criddle, Martin Laque, Alyce B Sheedy, Mark Anderson, Kathryn M. Bell, Kirsty Devine, Alex Scott, Ramesh Kumar, Sonia Armstrong, Emer Sutherland, Fleur Cantle, Sinead Helyer, Paul Riozzi, Hannah Cotton, Alice Downes, Helen Mollard, Damian Roland, Felix Hay, Christopher M. Gough, Sonya Finucane, Catherine Bevan, Rebecca Ramsay, Emily Walton, Julie‐Ann Maney, Elizabeth Dalzell, Muriel Millar, R J Howells, Andy Appelboam, Daisy Mackle, J. G. Small, Ashleigh Neil, V. Choudhery, Stewart MacLeod, J Browning, Thomas J. O’Neill, Julia Grahamslaw, Ami Parikh, Imogen Skene, Rhys Thomas, Katherine Potier de la Morandiere, Jill L Wilson, Donna Danziger, Derek Burke, Shammi Ramlakhan, Jayne Evans, Julie Morcombe, Stuart Gormley, Jason M Barling, Katrina Cathie, Jane Bayreuther, Ruth Ensom, Yasser Iqbal, Sarah Rounding, Joanne Mulligan, Claire L. Bell, Shona McLellan, Shona Leighton, T Sajjanhar, Moffat Nyirenda, Laura Crome, Neil Williamson, Anastasia Alcock, Sara Edwards, Jeffrey R. Morgan, Colin Powell, Chaniyil A Ramesh, Solomon Kamal-Uddin, Mike Linney, Katia Vamvakiti, Sharon Floyd, Gill Hobden,

Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsive status epilepticus in the UK; however, some evidence suggests that levetiracetam could be an effective and safer alternative. This trial compared the efficacy and safety of phenytoin and levetiracetam for second-line management of paediatric convulsive status epilepticus.This open-label, randomised clinical trial was undertaken at 30 UK emergency departments at secondary and tertiary care centres. ...

Tópico(s): Metabolism and Genetic Disorders

2019 - Elsevier BV | The Lancet

Artigo Acesso aberto Revisado por pares

Paul Lyons, James E. Peters, Federico Alberici, James Liley, Richard Coulson, William J. Astle, Chiara Baldini, Francesco Bonatti, María C. Cid, Heather Elding, Giacomo Emmi, Jörg T. Epplen, Loı̈c Guillevin, David Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, Stephen Leslie, Mark A. Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A. Ramirez, Barbara Rewerska, Georg Schett, Renato Alberto Sinico, Wojciech Szczeklik, Vladimı́r Tesař, Damjan Vukcevic, Mohammed Akil, Jonathan Barratt, Neil Basu, Adam S. Butterworth, Ian N Bruce, Michael Clarkson, Niall Conlon, Bhaskar Dasgupta, Timothy Doulton, Georgina Espígol‐Frigolé, Oliver Floßmann, Tianlu Li, Jolanta Gąsior, Gina Gregorini, Giuseppe Guida, José Hernández‐Rodríguez, Zdenka Hrušková, Amy W. Hudson, Ann Knight, Peter Lanyon, Raashid Luqmani, Malgorzata Magliano, Angelo A. Manfredi, Christopher Marguerie, Federica Maritati, Chiara Marvisi, Neil McHugh, Eamonn Molloy, Allan Motyer, Chetan Mukhtyar, Leonid Padyukov, Alberto Pesci, Sergio Prieto‐González, Marc Ramentol-Sintas, Petra Reis, Dario Roccatello, Patrizia Rovere‐Querini, Carlo Salvarani, Francesca Santarsia, Roser Soláns-Laqué, Nicole Soranzo, Jo Taylor, Julie Wessels, Jochen Zwerina, Benjamin Terrier, Richard A. Watts, Augusto Vaglio, Julia U. Holle, Chris Wallace, Kenneth G. C. Smith,

Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) specific for myeloperoxidase (MPO). Here, we describe a genome-wide association study in 676 EGPA cases and 6809 controls, that identifies 4 EGPA-associated loci through conventional case-control analysis, and 4 additional associations through a conditional false discovery rate approach. Many variants are also associated with ...

Tópico(s): Mast cells and histamine

2019 - Nature Portfolio | Nature Communications