Jonathan Northcroft, Lisa DePaulo, John Dugdale, Mark Stretton, Barbara Hall, Matthew Wall, George Lange, Terri Evans, Frank Parker, Jeff Dawson, David Brown, Paula Radcliffe, Jon Swain, James Clark, Nicholas Rufford, Rob Hughes, John Peter, Pam Barrett, Amanda Ursell, Jonathan Miller, James Wallis, Bill Gates, Judith Ransome, Susan d'Arcy, J D, Frank Whitford, Ivo Tennant, Sarena Braich, Sam Gilpin, Kathryn Cooper, Susan Bell, David Smith, Kirstie Hamilton City Editor, Tim Richards, Edin Hamzic, Rory Godson, Janet Walker Director of finance and business affairs, Dan Calms, E P, Clive Davis, Bill Nightingale, Karen Robinson, Penny Chorlton, Kathy Brewis, Richard Eaton, Sarah Gracle, Simon Wilde, Jenny Knight, Robert Sandall, Anthony Sattin, Stephan Lebert, Robert Winnett, Irwin Stelzer, Jane Moore, Matt Rudd, Robert Hewison, Peter Wilson, John O'Farrell, David Dougill, Nicholas Hellen Social Affairs Editor, York Membery, Allan Massie, Sophie Gilbert, Jad Adams, Geraldine Hackett, Thrasy Petropoulos, Sue Clayton, Robert Peston, Marian Martin, David Hewson, Mark Pitman, Jonathon Carr-Brown, Alasdair Reid, Jon Haywood, Fred Henley, Margarette Driscoll, Jeremy Clarkson, Stewart Lee, Graham Duffill, Edward Porter, Hugh Canning, Louise Taylor, Victoria Segal, Max Anderson, Kali Cooper, Jenny Shields, Monte Dann, Cheryl Markosky, Freda Ward, Peter Hain, John O'Donnell, Alan Armstrong, Kevin Jackson, Beatrice Aldin, Peter Oliver, Lydia Slater, Adam Nathan, Victoria Hervey, Melanie McDanagh, Paul Bailey, Steve Hamman, Lizzie Enfield, Richard Johnson, Ben Davies, Stuart Wavell, Paul Donovan, Alastair Hendy, Simon Mills, Steve Boyd, Uzi Mahnaiml, Lucinda Kemeny, Jasper Gerard, Derek Clements, Paul Driver, Simon Fanshawe, John Humphrys, Garth Pearce, Nicholas Hellen, John Follain, Norman Greensmith, Caroline Scott, Ian Hawkey, Shelley Von Strunckel, Patrick Garratt, Christopher Morgan, David Leppard, Amber Cowan, Paul Durman, Stuart Andrews, Alicia Wyllie, Sue Beenstock, Mark Edwards, Kirstie Hamilton, Susan Clark, David Lawrenson, Eben Black Chief Political Correspondent, David Dudley, Danny O'Brien, Christina Patterson, John Franklin, Victoria O'Brien, Alan Combes, Raymond Keene, Ron Martin, Rev Paul Flowers, Ian Evans, Gareth Huw Davies, Cosmo Landesman, David Leppard Home Affairs Editor, Robbie Hudson, Diana Wright, Alastair McQueen, William Peakin, Andy Knott, Siobhan Mason, Chris Partridge, Rebecca Mileham, Stephen Bleach, Paul Sullivan, Uzi Mahnaimi, Vaughan Nail, Michael Wright, Peta Bee, Dr Andrew Schapira, Jonathan Charter, Tim Moorey, Clive Aslet, Rosie Thomas, Keith Wheatley, Pat Butcher, Miranda Seymour, David Walsh, John Stern, Trevor Lewis, Marion Harris, Stephen Armstrong, Mark Macaskill, Twiggy, R W Johnson, Roland White, Jake Tapper, Garth Alexander, Gosia Kaszubska, Michael Leidig, Fiona Howat, Maurice Chittenden, Nick Hanna, M W, Richard Rae, Mark Franchetti, Ray Hutton, Frank Fitzgibbon, Saily Kinnes, Jonathan Leake, Sophie Kirkham, Belinda Scaburri, Michael Sheridan, John Wadham Director, Victoria Zisman, Marianne Hinton, John Harlow, Margaret Walters, James Marianski, Kevin Dowling, Dipesh Gadher, John Urbanek, Barry Collins, John Waples, Gareth Jenkins, Rupert Stelner, Iain Maitland, K L Hutchinson, Brian Glanville, H I M Smith, John Carey, Malcolm Wren, Tom Robbins, Harvey Jones, Sarah Curtis, Andrew Lycett, Stephen Pettitt, Peter Butler, Claudia Croft, Robert Johnston, Jonathan Leake Science Editor, Howard Jacobson, Margaret Kemp, Rw Johnson, Paul Dunman, Sally Kinnes, R H, Naomi Caine, Liam Clarke, David Wickers, Nigel Powell, Roger Dobson, Jason Henderson, Vivien Cosh, John Cornwell, Mark Hodson, Kenneth Bryan, Graham Norwood, Andrew Ban, Joe Lovejoy, Jonathan Futrell, Rupert Steiner, John Duffield, Jimmy Choo, Brian Pendreigh, Dan Cairns, Adrian Noble, Correlli Barnett, Mrs Mills, John Alzlewood, David Smith Economics Editor, Penny Perrick, Tom Deveson, Sarah Baxter, Jonathan Aitken, Walter Ellis, India Knight, Rev Donald Allister, Steve Grant, Nicola Gill, T R Houghton, Victoria Stanley, Dan Pearson, Rosie Waterhouse, Boris Schapiro, Bob Latham, Ian Watson,
... Two-day record under threat from Fastnet boats Flores takes Ascot by storm Tim Richards watches the ... Gallery Do the strand Picture Gallery Picture Gallery Laura Ashley … Amelie look Perfect Couple Knife & packer Why ...
2001 - Gale Group | Sunday Times HA GDA
Yelda A. Leal, Laura Flores, Ezequiel M. Fuentes‐Pananá, Roberto Cedillo‐Rivera, Javier Torres,
... MéxicoSearch for more papers by this authorLaura L. Flores, Laura L. Flores Division of Pulmonary and Critical Care ... MéxicoSearch for more papers by this authorLaura L. Flores, Laura L. Flores Division of Pulmonary and Critical Care Medicine, San ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2011 - Wiley | Helicobacter
Andrew Robson, Alan Howden, Simon Barnes Chief Sports Writer, Gabriele Marcotti, Phil Yates, Aidan Magee, Justin Whiteley, Martin Sewell, Andrew Billen, Leo Lewis Asia Business Correspondent, Alexandra Frean, Gary Duncan, Amanda Ursell, Peter Lansley, Neil Barraclough, Richard Hobson, David Rose, Ian Winrow, Philip Howard, Hilary Finch, David Chater, Ben Hoyle Arts Reporter, Joanna Bale, James Bone, Jeremy Kingston, Penny Wark, James Ducker, Moritz Volz, Richard Hobson One-Day Cricket Correspondent, Leon Pollock, Elizabeth Judge, David E. Lowry, Angus MacLeod Scottish Political Editor, Sam Marlowe, William Wordsworth, Jeremy Whittle, Peter Megann, Kevin Eason, John Russell, Kapish Narda, Joe Joseph, Andrew Norfolk, Robin Pagnamenta, Ben Webster Transport Correspondent, Valerie Elliott Countryside Editor, Frieda Hughes, Siobhan Kennedy, Anthony Browne, Gary Jacob, Michael Harvey, Jen Redshaw, Dan Sabbagh, Chris Riley, Alan Hamilton, David Sharrock Ireland Correspondent, Anthony Rodriguez, Richard Lloyd Parry, Sadie Gray, David Hands, Adam LeBor, Ron Lewis, Guillem Balague, Adam Sherwin Media Correspondent, Tim Teeman, Jeremy Plester, Derwent May, Fan Gang, Eric Campbell, Roy Richardson, U. A. Fanthorpe, Russell Kempson, Adam Uren, Gary Duncan Economics Editor, Carola Long, Oliver Kay, Tony Rees, Neil Harman, Michael Theodoulou, G. Woods, Siobhan Kennedy Mergers and Acquisitions Correspondent, John Westerby, Stephen Burgen, Jonathan Clayton Africa Correspondent, Angela Murphy Pro-Vice-Chancellor, John Hopkins Golf Correspondent, Rob Wright, David Watts, Robin Pagnamenta Health Industries Correspondent, Bernard Lagan, Neil Harman Tennis Correspondent, Tony Evans, Raymond Keene, Christine Buckley, Matthew Pryor, Tom Stoppard, Matt Hughes, Bruce Dessau, Sean O'Neill, Dr Tanya Byron, Leslie Bennetts, Kaveh Solhekol, Sylvia Townsend Warner, Peta Bee, Jeremy Page, Chris Campling, Helen Nugent, Richard Owen, Laura Deeley, Christopher Martin-Jenkins Chief Cricket Correspondent, Francesca Steele, Peter Dixon, Nick Hasell, Stewart Tendler, David Hands Rugby Correspondent, Tony Cascarino, Rosemary Bennett Social Affairs Correspondent, Julian Muscat, Mira Bar-Hillel, William Rees-Mogg, Nick Szczepanik, Dearbáil Jordan, Steve Hawkes, Tim Hames, Craig Lord, Ian Johns, Anthony Browne Chief Political Correspondent, Mike Rosewell, Anjana Ahuja, George Caulkin, Sonia Verma, Caitlin Moran, Neil Fisher, Walter Gammie, Raoul Franklin Vice-Chancellor, Richard Beeston, Richard Beeston Diplomatic Editor, Alex Davidson, Bojan Pancevski, Catherine Philp, Danny Baker, Ashling O'Connor, Asif Khan, Dr Thomas Stuttaford, Adrian Dence, Stephen Dalton, Richard Morrison, Alyson Rudd, Bill Edgar, Adam Sherwin, Alan Lee Racing Correspondent, Alexandra Blair Education Correspondent, Olav Bjortomt, Brian Clarke Fishing Correspondent, Fiona Hamilton, Richard Ford, Ed Hughes, Christopher Irvine,
... Hopes of European Glory on a Core … Sánchez Flores has the self-belief to be a champion, ...
2007 - Gale Group | TDA
... to thank my doctoral students Kathryn Fangsrud, Nelson Flores, Laura Kaplan, and Heather Woodley for their careful reading ... of Ofelia García (research director), Haiwen Chu, Nelson Flores, Heather Woodley, Laura Kaplan and Suzanne Dikker (research assistants).
Tópico(s): Linguistic Variation and Morphology
2011 - Routledge | International Journal of Bilingual Education and Bilingualism
Martin Berthoud, Stewart Tendler and Michael Harvey, David Adams, Helen Johnstone, Robert Cole, David Fannick QC, Andrew Pierce, Sally Brock, James Moore, Joanna Coles, Grace Bradberry, Sarah Potter, Tom Baldwin, Philip Webster and Jill Sherman, Peter Philp, Ben Bradshaw, Christopher M. Convey, Ivo Tennant, Philip Howard, Morag MacDonald, Clive Davis, Carl Mortished, Deborah Dooley, Roger Maynard, Thos: Whipham, Kevin Eason, Raymond Snoddy, Joe Joseph, Giles Coren, John O'Leary Education Editor, Peter Brown, K. J. Martin, Alice Lagnado and Tim Jones, Valerie Elliott Countryside Editor, Michael Baum, Norman T. Shepherd, Dominic Walsh, Tracey Croft, Debra Craine, Alix Ramsay Tennis Correspondent, Dr Jane Collins, Huon Mallalieu, Chalfont, Ruth Gledhill Religion Correspondent, Dalya Alberge Arts Correspondent, Michael Mulvihill, Libby Purves, Mark Inglefield, Oliver Wright, Bernard Connolly, Jenny MacArthur, John O'Leary, Reena SenGupta, Anatole Kaletsky, Charles Bremner, Joseph Connolly, Katherine Bergen, Edward Broome and Nick Szczepanik, Peter Barnard, Anthea Lawson, Tim Teeman, James Doran City Correspondent, D. Howarth General Manager, Peter Wright, Robert Cole City Correspondent, Edward Fennell, Paul Armstrong, HazelDavis and Jane Hoyal, Alison Be…, David Lister, Susan Clark, Louise Atkinson, Barry Millington, Simon de Bruxelles, Geoffrey Dean, Celia Brayfield, Steven Wise, Adam Jones, Anne Barrowclough, Raymond Keene, Alan McIvor Dean, David Robinson, Clive Mathieson, Paul Wilkinson, Michael C. Hughes, Huon Mallalleu, Marcus Binney Architecture Correspondent, Peta Bee, Christopher Walker Chief Ireland Correspondent, David Coombs, Richard Owen, Damian Whitworth, Michael Harvey and Stewart Tendler, Christopher Martin-Jenkins Chief Cricket Correspondent, Geoff seward and Iain MacKie, Roger Boyes, John Stern, Nick Kelly, Stewart Tendler, Carol Allen, Dalya Alberge, David Hands Rugby Correspondent, Alison Beckett, Julian Muscat, Adam Fresco, Tom Baldwin and Roland Watson, Martin Fletcher European Correspondent, John Cooper, Dominic Kennedy, Giles Whittell, Philip Webster Political Editor, Gabriella Gamini South America Correspondent, Mel Webb, Lord Irvine, Gerland Isaaman, Penny Lewis, Maureen Paton, Fay Weldon, George Caulkin, Chris McGrath, Michael Austin, Peter Riddell, Ben MacIntyre, Joseph Connly, Michael Gove, Nick Hassell, David Sinclair, Tim Jones, Richard A. Edwards, Martin Waller, Bob Bury, Nigel Hawkes Science Editor, Laura Peek, David Powell, Richard Morrison, Paul Gordon Saker and Tepo Din, Elizabeth Judge, Linus Gregoriadis and Adam Sage, Simon Crompton, Susan MacDonald, Andrew Finkel, Robert Whymant, Allan Hall, Alan Lee Racing Correspondent, Sally Patten, Roland Watson Chief Political Correspondent, Lea Paterson Economics Correspondent, Brian Clarke Fishing Correspondent, James Doran and Lea Paterson, Edward Gorman Sailing Correspondent, Patience Wheatcroft, Christopher Irvine, John Wadham Director,
... No Title Picture Gallery No Title Country Rosie Flores Borderline, WC2 POP Luke Vibert and B. J. ...
2000 - Gale Group | TDA
Monika Sadlonova, Nicole B. Katz, Jane S. Jurayj, Laura Flores, Christopher M. Celano, Christine A. F. Von Arnim, Julie K. Silver,
... Katz, Nicole B. MD; Jurayj, Jane S. MD; Flores, Laura PhD; Celano, Christopher M. MD; von Arnim, Christine ...
Tópico(s): Nutrition and Health in Aging
2023 - Lippincott Williams & Wilkins | International Anesthesiology Clinics
Kevin Winthrop, B. Kubak, David A. Pegues, Catherine Hufana, Pam Costamagna, Ed Desmond, C A Sanders, PAUL T. SHEN, Laura Flores, Eugene Osborne, David A. Bruckner, Jennifer Flood,
... Berkeley, CASearch for more papers by this authorLaura Flores-Ibarra, Laura Flores-Ibarra Department of Epidemiology, University of California ... Berkeley, CASearch for more papers by this authorLaura Flores-Ibarra, Laura Flores-Ibarra Department of Epidemiology, University of California at ...
Tópico(s): Infectious Diseases and Tuberculosis
2004 - Elsevier BV | American Journal of Transplantation
... article:Norberto P. Giannini, Fernando Abdala, David A. Flores, Laura A. B. Wilson Ontogenetic allometry reveals the imprint ...
Tópico(s): Marine animal studies overview
1962 - University of Chicago Press | Physiological Zoology
... 10.1016/j.jbusres.2021.11.074Yvette G. Flores, Laura Grindstaff, Lisceth Brazil-Cruz Making Visible the Invisible: ...
Tópico(s): Management and Organizational Studies
1983 - University of Chicago Press | American Journal of Sociology
F. Gómez-Valdivia, Alejandro Parés‐Sierra, Ana Laura Flores‐Morales,
... MéxicoSearch for more papers by this authorAna Laura Flores-Morales, Ana Laura Flores-Morales Facultad de Ciencias Marinas, Universidad Autónoma ... MéxicoSearch for more papers by this authorAna Laura Flores-Morales, Ana Laura Flores-Morales Facultad de Ciencias Marinas, Universidad Autónoma de ...
Tópico(s): Climate variability and models
2017 - Wiley | Journal of Geophysical Research Oceans
Yelda A. Leal, Laura Flores, Laura B. García-Cortés, Roberto Cedillo‐Rivera, Javier Torres,
Background Numerous serologic tests are available for the diagnosis of H. pylori infection in children. Common designs of antibody-based detection tests are ELISA and Western Blot (WB). For developing countries with limited laboratory resources and access, ELISA would be the preferred method because of its simplicity, lower cost and speed. Although in adults ELISA has proven to be highly accurate in diagnosing H. pylori infection; in children, it has shown variable accuracy. Methods/Findings We conducted ...
Tópico(s): Intestinal and Peritoneal Adhesions
2008 - Public Library of Science | PLoS ONE
Bartolomé Carrilero Fernández, Laura Murcia Flores, Laura Martínez, Manuel Segovia,
espanolLa enfermedad de Chagas es endemica en America Latina y esta causada por el parasito T. cruzi. El benznidazol es la droga usada con mayor frecuencia para el tratamiento etiologico de la enfermedad. Su eficacia varia segun la fase de la misma y los efectos secundarios son frecuentes. Este es un estudio prospectivo que describe los efectos secundarios del tratamiento con benznidazol en una cohorte de 373 pacientes cronicos. De estos, el 40,2% presento reacciones adversas siendo las de tipo ...
Tópico(s): Trypanosoma species research and implications
2011 - | Revista española de quimioterapia. Suplemento
Juan Carlos Núñez-Enríquez, Ana Elena Gil-Hernández, Elva Jiménez‐Hernández, Arturo Fajardo‐Gutiérrez, Aurora Medina‐Sansón, Janet Flores‐Lujano, Laura Eugenia Espinoza‐Hernández, David Aldebarán Duarte-Rodríguez, Raquel Amador‐Sánchez, José Gabriel Peñaloza‐González, José Refugio Torres‐Nava, Rosa Martha Espinosa‐Elizondo, Luz Victoria Flores‐Villegas, Laura Elizabeth Merino‐Pasaye, María Luisa Pérez‐Saldivar, Elisa Dorantes‐Acosta, Beatriz Cortés-Herrera, Karina Anastacia Solís‐Labastida, Nora Nancy Núñez-Villegas, Martha Margarita Velázquez‐Aviña, Angélica Rangel-López, Ana Itamar González‐Ávila, Jessica Denisse Santillán-Juárez, Alejandra Jimena García-Velázquez, Silvia Jiménez‐Morales, Carolina Bekker-Méndez, Haydeé Rosas‐Vargas, Minerva Mata‐Rocha, Omar Alejandro Sepúlveda‐Robles, Jorge Alfonso Martín‐Trejo, Juan Manuel Mejίa‐Aranguré,
Mexico City has one of the highest incidences and mortality rates of acute lymphoblastic leukemia (ALL) in the world and a high frequency of early relapses (17%) and early mortality (15%). Otherwise, childhood overweight and obesity are reaching epidemic proportions. They have been associated with poor outcomes in children with ALL. The aim of present study was to identify if overweight and obesity are predictors of early mortality and relapse in Mexican children with ALL.A multicenter cohort study ...
Tópico(s): Cancer Risks and Factors
2019 - BioMed Central | BMC Cancer
Tere Flores, Laura J. Wagner, Hector E. Flores,
Tópico(s): Plant nutrient uptake and metabolism
1993 - Springer Science+Business Media | In Vitro Cellular & Developmental Biology - Plant
Laura Menatti, Mikel Subiza‐Pérez, Arturo Eduardo Villalpando-Flores, Laura Vozmediano, César San Juan Guillén,
This study explores the roles of place attachment and place identification in the evaluation of the restorative potential of landscapes. Two hundred university students recruited at campuses in the Basque Country (Spain) and Chile evaluated the restorative value of a set of landscape photographs including local and non-local locations. The results indicated that local natural landscapes were preferred and assessed as more restorative as compared to non-local ones, and that place attachment and identification ...
Tópico(s): Land Use and Ecosystem Services
2019 - Elsevier BV | Journal of Environmental Psychology
Albert Meier, Jerry W. Dusseau,
... doi.org/10.1093/icb/icac064Victoria S. Farrar, Laura Flores, Rechelle C. Viernes, Laura Ornelas Pereira, Susan Mushtari, Rebecca M. Calisi Prolactin ...
Tópico(s): Reproductive Physiology in Livestock
1968 - University of Chicago Press | Physiological Zoology
Patrick W. Cervantes, Bruno Martorelli Di Genova, Billy Joel Erazo Flores, Laura J. Knoll,
Toxoplasma gondii infection activates pattern recognition receptor (PRR) pathways that drive innate inflammatory responses to control infection. Necroptosis is a proinflammatory cell death pathway apart from the innate immune response that has evolved to control pathogenic infection. In this study, we further defined the role of Z-DNA binding protein 1 (ZBP1) as a PRR and assessed its contribution to necroptosis as a host protection mechanism to T. gondii infection. We found that ZBP1 does not induce ...
Tópico(s): Inflammasome and immune disorders
2021 - American Society for Microbiology | Infection and Immunity
Liliana Aranda‐Lara, Blanca Ocampo‐García, Keila Isaac‐Olivé, Guillermina Ferro‐Flores, Laura Meléndez‐Alafort, Enrique Morales-Ávila,
Polymeric nanoparticles encompass micelles and dendrimers. They are used for improving or controlling the action of the loaded therapy or imaging agent, including radionuclides. Some radionuclides possess properties appropriate for simultaneous imaging and therapy of a disease and are therefore called theranostic. The diversity in core materials and surface modification, as well as radiolabeling strategies, offers multiples possibilities for preparing polymeric nanoparticles using radionuclides. ...
Tópico(s): Advanced Polymer Synthesis and Characterization
2021 - Wiley | Macromolecular Bioscience
Olga Escuredo, María Shantal Rodríguez‐Flores, Laura Meno, M. Carmen Seijo,
There is an increase in the consumption of natural foods with healthy benefits such as honey. The physicochemical composition contributes to the particularities of honey that differ depending on the botanical origin. Botanical and geographical declaration protects consumers from possible fraud and ensures the quality of the product. The objective of this study was to develop prediction models using a portable near-Infrared (MicroNIR) Spectroscopy to contribute to authenticate honeys from Northwest ...
Tópico(s): Insect and Pesticide Research
2021 - Multidisciplinary Digital Publishing Institute | Foods
Osval A. Montesinos‐López, Abelardo Montesinos‐López, Paulino Pérez‐Rodríguez, José Alberto Barrón‐López, Johannes W. R. Martini, Silvia B. Fajardo-Flores, Laura S. Gaytán-Lugo, Pedro C. Santana-Mancilla, José Crossa,
Several conventional genomic Bayesian (or no Bayesian) prediction methods have been proposed including the standard additive genetic effect model for which the variance components are estimated with mixed model equations. In recent years, deep learning (DL) methods have been considered in the context of genomic prediction. The DL methods are nonparametric models providing flexibility to adapt to complicated associations between data and output with the ability to adapt to very complex patterns.
Tópico(s): Genetics and Plant Breeding
2021 - BioMed Central | BMC Genomics
Mónica Flores, Laura Perea-Sanz, José Javier López-Díez, Carmela Belloch,
The contribution of free amino acids and thiamine to the production of potent meat aroma compounds in nitrite-reduced, dry-fermented sausages inoculated with a D. hansenii strain was the objective of this study. For this, three different sausage formulations were manufactured; a control and two formulations reduced by half in nitrate and nitrite and one of them inoculated with D. hansenii. Free amino acids, thiamine content and savoury volatile compounds were analysed. Eleven savoury volatile compounds ...
Tópico(s): Food Quality and Safety Studies
2021 - Elsevier BV | Food Chemistry
Jagmohan Kalra, Allan M. Grossman, Burton A. Krumholz, Sidney Chen, Mary Ann Tinker, Glorioso T. Flores, Laura Molho, Engracio P. Cortes,
We report the case of a 71-year-old woman with advanced squamous carcinoma of the vulva who achieved marked tumor regression following therapy with 5-fluorouracil and mitomycin combined with preoperative radiotherapy. The patient underwent radical vulvectomy. On microscopic examination of the lesion, only a minute intradermal focus of apparently viable squamous cell carcinoma with no connection to the overlying epidermis could be seen. This multidisciplinary approach for advanced carcinoma of the ...
Tópico(s): Cervical Cancer and HPV Research
1981 - Elsevier BV | Gynecologic Oncology
Luís I. Sánchez-Abarca, Silvia Gutierrez-Cosío, Carlos Santamaría, Teresa Caballero‐Velázquez, Belén Blanco, Carmen Herrero-Sánchez, Juan Luis Garcı́a, Soraya Carrancio, Pilar Hernández-Campo, Xavier González-Argenté, Teresa Flores, Laura Ciudad, Esteban Ballestar, Consuelo del Cañizo, Jesús F. San Miguel, José Antonio Pérez‐Simón,
Abstract Cytokine genes are targets of multiple epigenetic mechanisms in T lymphocytes. 5-azacytidine (5-azaC) is a nucleoside-based DNA methyltransferase inhibitor that induces demethylation and gene reactivation. In the current study, we analyzed the effect of 5-azaC in T-cell function and observed that 5-azaC inhibits T-cell proliferation and activation, blocking cell cycle in the G0 to G1 phase and decreasing the production of proinflammatory cytokines such as tumor necrosis factor-α and interferon- ...
Tópico(s): Cytomegalovirus and herpesvirus research
2009 - Elsevier BV | Blood
Jorge Gutiérrez, María Josefa López Núñez‐Flores, Laura V. Gómez‐Ros, Esther Novo‐Uzal, Alberto Esteban‐Carrasco, José Dı́az, Mariana Sottomayor, Juan Cuello, A. Ros Barceló,
Tópico(s): Plant Gene Expression Analysis
2009 - Springer Science+Business Media | Planta
Luis Vida Pérez, Federico Gómez Camacho, Valle García Sánchez, Eva M.a Iglesias Flores, Laura Castillo Molina, Antonio Cerezo Ruiz, Luis Casáis Juanena, Juan F. Vega,
Aunque parece que no hay un aumento en la prevalencia de infección por el virus de la hepatitis B (VHB) en pacientes con enfermedad inflamatoria intestinal (EII), se especula que la necesidad de exploraciones invasivas e intervenciones quirúrgicas sitúa a estos pacientes dentro de un grupo de riesgo para contraer esta infección. Además, el uso cada vez más frecuente de inmunomoduladores puede conducir a una reactivación vírica latente. El objetivo de este trabajo fue evaluar la eficacia de la vacuna ...
Tópico(s): Hepatitis C virus research
2009 - Elsevier BV | Medicina Clínica
Todd J. Crocco, Travis Gullett, Stephen M. Davis, Nicole Flores, Laura Sauerbeck, Edward C. Jauch, Billie Threlkeld, Brian Pio, Michael Ottaway, Arthur Pancioli, Thomas C. Chenier,
Studies have demonstrated the importance of early stroke treatment. If a neuroprotective agent (NA) clinical trial is successful, the greatest benefit might be attained with early prehospital administration. This study determined the potential reduction in time to treatment of stroke patients when NAs were administered in the prehospital setting.Twenty-three urban emergency medical services (EMS) agencies participated in this study. Prehospital personnel completed a stroke assessment checklist on ...
Tópico(s): Trauma and Emergency Care Studies
2003 - Lippincott Williams & Wilkins | Stroke
Savita Manglik, Eugene Flores, Laura Lubarsky, Fernando Fernandez, Vijay L. Chhibber, John A. Tayek,
Objective To identify the incidence of secondary adrenal insufficiency in severe sepsis. Design Prospective clinical trial testing 100 patients with a 250-μg adrenocorticotropic hormone (ACTH) stimulation test. Setting County-university teaching hospital. Patients One hundred patients with sepsis and septic shock. Forty patients had bacteremia and 17% shock. Interventions ACTH, cortisol, aldosterone, and electrolyte concentrations were measured at baseline. Cortisol and aldosterone were measured ...
Tópico(s): Sepsis Diagnosis and Treatment
2003 - Lippincott Williams & Wilkins | Critical Care Medicine
Zhen Zhao, Johannes Zuber, Ernesto Díaz-Flores, Laura Lintault, Scott C. Kogan, Kevin Shannon, Scott W. Lowe,
The p53 tumor suppressor limits proliferation in response to cellular stress through several mechanisms. Here, we test whether the recently described ability of p53 to limit stem cell self-renewal suppresses tumorigenesis in acute myeloid leukemia (AML), an aggressive cancer in which p53 mutations are associated with drug resistance and adverse outcome. Our approach combined mosaic mouse models, Cre-lox technology, and in vivo RNAi to disable p53 and simultaneously activate endogenous Kras G12D —a ...
Tópico(s): Protein Degradation and Inhibitors
2010 - Cold Spring Harbor Laboratory Press | Genes & Development
Fernando Álvarez, Edgar Flores, Laura V. Castro, J. G. Hernández, A. López, F. Vázquez,
This work presents a theoretical study of the effects of different molecular weights of a triblock co-polymer ethylene oxide/propylene oxide/ethylene oxide, bifunctionalized with ethalamine, on the coalescence of water drops imbibed in a crude oil environment. The polymer/crude oil/water (PCW) time evolution of the emulsion was simulated using the framework of the dissipative particle dynamics (DPD) technique. The bead−bead interactions of the molecular components were calculated using the correlation ...
Tópico(s): Surfactants and Colloidal Systems
2010 - American Chemical Society | Energy & Fuels
Roberto Flore, Laura Gerardino, Angelo Santoliquido, Cesare Catananti, P. Pola, Paolo Tondi,
Background Healthy workers who stand for prolonged periods show enhanced production of reactive oxygen species (ROS) in their systemic circulation. Oxidative stress is thought to be a risk factor for chronic venous insufficiency and other systemic diseases. Aim To evaluate the effectiveness of compression stockings in the prevention of oxidative stress at work. Methods ROS and venous pressure of the lower limbs were measured in 55 theatre nurses who stood in the operating theatre for >6 h, 23 industrial ...
Tópico(s): Thermoregulation and physiological responses
2007 - Oxford University Press | Occupational Medicine