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Andrew Robson, Matt Dickinson Chief Sports Correspondent, Larry Spence, Andrew Billen, Joanne Christie, Jack Lonergan, Frances Gibb Legal Editor, Simon Barnes, David Wighton Business Editor, Katie Perrior, Magnus Linklater, Robert Lindsay, Paul Hoggart, Catherine Boyle, David Rose, Ivo Tennant, Michael Evans Defence Editor, Philip Howard, Christine Seib, Ben Hoyle Arts Reporter, James Bone, Jonathan Bate, James Ducker, Murad Ahmed, Rachel Campbell-Johnston, Rosalind Renshaw, Carl Mortished, Patrick Kidd, Gráinne Gilmore Economics Correspondent, Sam Marlowe, James Hider, Martin E. Simons, Geoff Brown, Martin Samuel Chief Football Correspondent, Joe Joseph, Andrew Norfolk, Mark Barrowcliffe, Jack Malvern, Steve Bird, Debra Craine, Gary Jacob, Melanie Reid, Laura Lovett, Dalya Alberge Arts Correspondent, Richard Ford Home Correspondent, Peter Millar, Dr Robert Gutfreund-Walmsley, Lucille Sher, Valerie Elliott Consumer Editor, Jonathan Richards, Ron Lewis, Adam Sherwin Media Correspondent, Geoffrey Hall, Anthony E. C. W. Spencer, Lilly Peel, Susan Thompson, Hugo Rifkind, David Budworth, Deputy Personal Finance Editor, Derwent May, Tim Teeman, Anthony Hollis, Katie Roiphe, Douglas Henderson, Suzy Jagger, Mark Henderson Science Editor, Michael Theodoulou, John Westerby, Neil Harman, Tom Baldwin, Christopher Martin-Jenkins, Douglas Rankine, Simon de Bruxelles, Rob Wright, Edward Gorman Motor Racing Correspondent, Martin Samuel, Raymond Keene, Matt Hughes, John Cooney, Chris Campling, Fran Yeoman, Adam Fresco Crime Correspondent, Bronwen Maddox, Nigel Brown, Cllr David Hibbert, Roger Boyes, Francesca Steele, Kenneth Denby, Nigel Barraclough, Nick Hasell, Giles Gibbons, Carolyn Asome, David Hands Rugby Correspondent, Tom Dart, Paul Simons, Michael Herman, Philip Webster Political Editor, Rowel W. Samuels, Steve Hawkes, Thomas Catán, Kevin Eason Sports News Correspondent, Alice Fordham, Neil Fisher, Michael Austin, Mike Sant, Joe Clay, Colin Pomeroy, Andrew Lycett, Robert Whelan, Martin Waller, Benedict Nightingale, Paul Larter, Stephen Dalton, Nicola Woolcock, Helen Logan, Richard Morrison, Frances Gibb, Alice Miles, Alan Lee Racing Correspondent, Olav Bjortomt, Mike Atherton Chief Cricket Correspondent, Alexandra Soveral, Richard Ford, Dr Milton Wainwright,

Index The Times Ministers driven to U-turn on road taxes Car and fuel duty rises likely to be scrapped Backbench revolt and hauliers force rethink Index ...

2008 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Laura García‐Otero, I. Soveral, Á. Sepúlveda‐Martínez, M. Rodríguez‐López, X. Torres, L. Guirado, L. Nogué, Brenda Valenzuela‐Alcaráz, J. Martı́nez, E. Gratacós, O. Gómez, F. Crispi,

To construct nomograms for fetal cardiac, ventricular and atrial relative size and geometry parameters from 18 to 41 weeks' gestation using a low-risk population of singleton pregnancies.This was a prospective cohort study of 602 low-risk singleton pregnancies undergoing comprehensive fetal echocardiography, from 18 to 41 weeks of gestation, to assess fetal cardiac, atrial and ventricular relative size and sphericity, ventricular dominance, wall asymmetry and relative wall thickness. Intra- and ...

Tópico(s): Cardiovascular Function and Risk Factors

2020 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

I. Soveral, F. Crispi, L. Guirado, Laura García‐Otero, X. Torres, M. Bennásar, Á. Sepúlveda‐Martínez, L. Nogué, E. Gratacós, J. Martı́nez, Bart Bijnens, Mark K. Friedberg, O. Gómez,

Fetal cardiac function can be evaluated using a variety of parameters. Among these, cardiac cycle time-related parameters, such as filling time fraction (FTF) and ejection time fraction (ETF), are promising but rarely studied. We aimed to report the feasibility and reproducibility of fetal FTF and ETF measurements using pulsed-wave Doppler, to provide reference ranges for fetal FTF and ETF, after evaluating their relationship with heart rate (HR), gestational age (GA) and estimated fetal weight (EFW), ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2020 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Revisado por pares

L. Guirado, F. Crispi, I. Soveral, Brenda Valenzuela‐Alcaráz, M. Rodríguez‐López, Laura García‐Otero, X. Torres, Á. Sepúlveda‐Martínez, Maria C. Escobar‐Diaz, Josep M. Martínez, Mark K. Friedberg, E. Gratacós, O. Gómez,

<b><i>Objectives:</i></b> Fetal right ventricular (RV) function assessment is challenging due to the RV geometry and limitations of in utero assessment. Postnatally, 2D echocardiographic RV fractional area change (FAC) is used to assess RV global systolic function by calculating the percentage of change in RV area from systole to diastole. Reports on FAC are scarce in prenatal life, and nomograms throughout pregnancy are not available. Our aims were (1) to study prenatal RV ...

Tópico(s): Cardiovascular Issues in Pregnancy

2019 - Karger Publishers | Fetal Diagnosis and Therapy

Artigo Acesso aberto Revisado por pares

Á. Sepúlveda‐Martínez, Laura García‐Otero, I. Soveral, L. Guirado, Brenda Valenzuela‐Alcaráz, X. Torres, M. Rodríguez‐López, E. Gratacós, O. Gómez, F. Crispi,

M-mode and 2D have been proposed for evaluating fetal myocardial thickness. However, studies comparing the performance of both modalities are lacking. We aimed to compare 2D versus M-mode reproducibility for assessing myocardial wall thicknesses.A prospective study including 45 healthy fetuses from low-risk pregnancies evaluated between 18 and 41 weeks of gestation. Left and right ventricular free-wall and septal myocardial thicknesses were measured at end-diastole (ED) and end-systole (ES) in transverse ...

Tópico(s): Cardiovascular Issues in Pregnancy

2018 - Informa | The Journal of Maternal-Fetal & Neonatal Medicine

Artigo Revisado por pares

Francisco Javier Molina‐Hidalgo, Laura Medina‐Puche, Samuel Gelis, José Ramos, Farzana Sabir, Graça Soveral, Catarina Prista, Raquel Iglesias‐Fernández, José L. Caballero, Juan Muñoz‐Blanco, Rosario Blanco‐Portales,

Strawberry fruit (Fragaria × ananassa) is a soft fruit with high water content at ripe stage (more than 90% of its fresh weight). Aquaporins play an important role in plant water homeostasis, through the facilitation of water transport and solutes. We report the role played by FaNIP1;1 in the receptacle ripening process. The analysis by qRT-PCR of FaNIP1;1 showed that this gene is mainly expressed in fruit receptacle and has a ripening-related expression pattern that was accompanied by an increase in ...

Tópico(s): Ion Transport and Channel Regulation

2015 - Elsevier BV | Plant Science

Artigo Acesso aberto Revisado por pares

Laura García‐Otero, O. Gómez, M. Rodríguez‐López, X. Torres, I. Soveral, Á. Sepúlveda‐Martínez, L. Guirado, Brenda Valenzuela‐Alcaráz, Marta López, Josep Maria Martínez, E. Gratacós, F. Crispi,

<b><i>Objective:</i></b> There is a need for standardized reference values for cardiac dimensions in prenatal life. The objective of the present study was to construct nomograms for fetal cardiac dimensions using a well-defined echocardiographic methodology in a low-risk population. <b><i>Methods:</i></b> This is a prospective cohort study including 602 low-risk singleton pregnancies undergoing a standardized fetal echocardiography to accurately assess ...

Tópico(s): Congenital Diaphragmatic Hernia Studies

2019 - Karger Publishers | Fetal Diagnosis and Therapy

Artigo Acesso aberto Revisado por pares

C. Murillo Bravo, M. Larroya Sola, F. Crispi, O. Gómez, I. Soveral, Laura García‐Otero, Claudia Orden Rueda, Silvia Ferrero, Laia Grau, Montse Palacio, Teresa Cobo,

To assess the influence of intraamniotic infection and/or inflammation (IAI) on the fetal cardiac structure in preterm labour (PTL) and/or preterm prelabour rupture of membranes (PPROM). Prospective cohort study (2018-2019) including singleton pregnancies with PTL and/or PPROM with an amniocentesis at admission; and asymptomatic (non-exposed) women. We compared women with PTL and/or PPROM with IAI (n = 18), without IAI (n = 22) and a non-exposed group (n = 20). IAI was defined by a positive culture and/or high ...

Tópico(s): Pregnancy and preeclampsia studies

2020 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

I. Soveral, L. Guirado, Laura García‐Otero, X.F. Torres Montebruno, Á. Sepúlveda‐Martínez, Maria C. Escobar‐Diaz, J. Martı́nez, E. Gratacós, F. Crispi, O. Gómez,

The systolic (S) to diastolic (D) duration ratio (S/D) has been proposed as a useful index to assess ventricular function in some pediatric cardiopathies. Prenatal reports on S/D are scarce and nomograms are not available. We aimed to establish normal values for left (LV) and right ventricular (RV) S/D ratios in normal fetuses and to investigate its relation to heart rate (HR), gestational age (GA) and estimated fetal weight (EFW). Prospective cohort study including 602 low-risk singleton pregnancies (GA ...

Tópico(s): Pregnancy and preeclampsia studies

2019 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Revisado por pares

Gelfman Laura, I. Soveral, L. Nogué, M. Pérez‐Cruz, M. Bennásar, M. Escobar, J. Martı́nez, María Dolores Gómez‐Roig, E. Gratacós, F. Crispi, O. Gómez,

The aim of this study was to investigate the differences in cardiac filling (FTF) and ejection time (ETF) fractions between fetuses with right ventricle tract obstruction, including pulmonary stenosis (PS) and tetralogy of Fallot with pulmonary stenosis (ToF-PS) and healthy fetuses. A total of 13 fetuses with PS and 34 with ToF-PS matched by gestational age (GA) at scan with 94 healthy fetuses; were included in the study. A comprehensive echocardiography was performed including the evaluation of biventricular ...

Tópico(s): Pregnancy and preeclampsia studies

2021 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

O. Gómez, L. Guirado, I. Soveral, Brenda Valenzuela‐Alcaráz, M. Rodríguez‐López, Laura García‐Otero, X. Torres, Á. Sepúlveda‐Martínez, M. Escobar, J. Martı́nez, Mark K. Friedberg, E. Gratacós, F. Crispi,

Right ventricular (RV) fractional area change (FAC) is a 2D-echocardiographic parameter to assess RV global systolic function. Fetal reference ranges are not yet available. Our aims were: to study prenatal RV FAC feasibility and reproducibility and to construct nomograms for RV FAC and end-diastolic and end-systolic RV areas throughout gestation. Prospective cohort study including 602 low-risk singleton pregnancies undergoing a fetal echocardiography from 18-41 weeks of gestation. RV end-diastolic ...

Tópico(s): Pregnancy and preeclampsia studies

2019 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Vítor Borges, Joana Isidro, Nídia S. Trovão, Sílvia Duarte, Helena Cortes Martins, Hugo Martiniano, Isabel Gordo, Ricardo B. Leite, Luı́s Vieira, Agostinho José S. Lira, Aida M. Sousa Fernandes, Alexandra Estrada, Alexandra Nunes, Alfredo Sotero Alves Rodrigues, Ana Castro Caldas, Ana Constança, Ana Margarida Henriques, Ana Miguel Matos, Ana Oliveira, Ana Paula Soares Dias, Ana Pelerito, Ana Rita Couto, Anabela Vilares, Antônio Albuquerque, Baltazar Nunes, Bruna R. Gouveia, Carina Rodrigues, Carla Feliciano, Carla Roque, Carlos Cardoso, Carlos Sousa, Cathy Paulino, Célia Bettencourt, Cláudia C. Branco, Cláudia Nunes dos Santos, Conceição Godinho, Constantino Caetano, Cristina Correia, Cristina Toscano, Cristina Veríssimo, Daniela Silva, Diana Patrícia Pinto da Silva, Eliana Costa, Elizabeth Pádua, Fátima Martins, Fátima Vale, Fernanda Vilarinho, Fernando Branca, Filomena Caldeira, Filomena Lacerda, Francisca Rocha, M.P.F. Graça, Helena Ribeiro, Helena Rodrigues, Herberto Jesus, Hugo Sousa, Idalina Ferreira, Inês Baldaque, Inês Costa, Inês Gomes, Inna Slobidnyk, Isabel Soares de Albergaria, Isabel Dias, Isabel Fernandes, Isabel Lopes de Carvalho, Ivone Água‐Doce, Jácome Bruges‐Armas, J M Guerra Ramos, João Carlos Sousa, João Costa, João Victor Leite Dias, João Rodrigues, João Sobral, Jorge Machado, Jorge Meneses, José Antônio Barreto Alves, José Vicente Constantino, Laura Brum, Leonor Silveira, Líbia Zé‐Zé, Lídia Santos, Ludivina Freitas, Luís Silva, Luísa Mota‐Vieira, Lurdes Lopes, Lummy Monteiro, M. T. Faria, Margarida Farinha, Margarida Vaz, M. Alice Pinto, Maria Ana Pessanha, Maria Beatriz Tomaz, Maria Calle Vellés, Maria da Graça Maciel de Soveral, Maria Helena Ramos, María Isabel Veiga, Maria João Gargaté, Maria João Peres, Maria José Borrego, Maria Matos Figueiredo, Mariana Leonel Martins, Mariana Thereza Rodrigues Viana, Maurício Melim, Miguel Babarro Jorreto, Miguel Fevereiro, Miguel Pinheiro, Mónica Oleastro, Nair Seixas, Nelson Ventura, Nuno Verdasca, O. A. Dalla Costa, Patrícia Barros, Patrícia Fonseca, Patricia Martínez‐Miguel, Maria Paula Bajanca-Lavado, Paula Branquinho, Paula Palminha, Paula Matias Soares, Paula Valente, Paulo Leandro, Paulo Pereira, Pedro Henrique Cardoso, Pedro Pechirra, Pedro Ramos, Raquel Neves, Raquel Rocha, Raquel Rodrigues, Raquel Sabino, Regina Sá, Ricardo Filipe Romão Ferreira, Ricardo Gouveia Rodrigues, Rita C. Veloso, Rita Cordeiro, Rita Côrte‐Real, Rita de Sousa, Rita Gralha, Rita Macedo, Rita Matos, Rita Rodrigues, S. Paulo, SARA MELISSA LAGO SOUSA, Sílvia Lopo, Sónia Marta Santos Magalhães, Sônia Rodrigues, Sónia Silva, Susana Ladeiro, Susana Martins, Susana Pereira Silva, Teresa Salvado, Tiago C. Luís, Valquíria Alves, Vera Manageiro, Raquel Guiomar, João Paulo Gomes,

Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration with more than 50 laboratories distributed nationwide.By applying recent phylodynamic models that allow integration of individual-based travel history, we reconstructed and characterized the spatio-temporal dynamics of SARS-CoV-2 introductions and early dissemination in Portugal.We detected at least 277 independent SARS-CoV-2 introductions, ...

Tópico(s): Evolution and Genetic Dynamics

2022 - Nature Portfolio | Communications Medicine

Artigo Acesso aberto Revisado por pares

Á. Sepúlveda‐Martínez, Laura García‐Otero, I. Soveral, Lluís Girado, Brenda Valenzuela‐Alcaráz, X. Torres, M. Bennásar, J. Martı́nez, E. Gratacós, O. Gómez, F. Crispi,

M-mode and 2D modalities are both used for measuring fetal myocardial wall thicknesses. However, studies comparing the performance of both modalities are lacking. We aimed to compare the reproducibility of 2D vs M-mode for measuring myocardial wall thicknesses. A prospective study including 45 healthy fetuses from low-risk pregnancies evaluated between 18 and 41 weeks of gestation. Left and right ventricular free-wall and septal myocardial thicknesses were measured at end-diastole (d) and end-systole ( ...

Tópico(s): Cardiovascular Issues in Pregnancy

2017 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

L. Youssef, Jezid Miranda, Cristina Paulés, Laura Carrera‐García, X. Torres, I. Soveral, E. Gratacós, F. Crispi,

The aim of this study was to describe fetal cardiac structure and function in pregnancies complicated by pre-eclampsia (PE) and/or fetal growth restriction (FGR) as compared to uncomplicated pregnancies. A prospective cohort study of: 112 pregnancies complicated by normotensive FGR (n=36), PE without FGR (n=34), PE with FGR (n=42) and 111 uncomplicated pregnancies, matched by gestational age at assessment. Fetal echocardiography was performed at diagnosis or recruitment for controls. B-type natriuretic ...

Tópico(s): Pregnancy and preeclampsia studies

2018 - Wiley | Ultrasound in Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

F. Crispi, L. Guirado, Onelis Góngora Gómez, Brenda Valenzuela‐Alcaráz, Laura García‐Otero, X. Torres, Á. Sepúlveda‐Martínez, J. M. Martínez, E. Gratacós, I. Soveral,

To compare repeatability between left (LV) and right (RV) systolic function, evaluated by M-mode and 2D-echocardiography. Prospective study including 45 healthy fetuses from low-risk pregnant women evaluated between 18 and 40 weeks of gestation. Biventricular ejection fraction (EF= [(End-diastolic (ED) volume-End-systolic (ES) volume)/ED volume]*100) was evaluated in a transverse 4-chamber view by M-mode as described by Theicholz. Biventricular systolic function was also evaluated in an apical or basal ...

Tópico(s): Cardiovascular Issues in Pregnancy

2017 - Wiley | Ultrasound in Obstetrics and Gynecology

Errata Acesso aberto Revisado por pares

Christopher I. Cassady, Edward P. Buchanan, Matthew G. Kaufman, Charles H. Hyman, W. Lee, Mehernoor F. Watcha, Helena K. Hippard, Olutoyin A. Olutoye, David Y. Khechoyan, Laura A. Monson, María Dolores Gómez‐Roig, Edurne Mazarico, Marta Díaz, Antonio Vela, E. Gratacós, F. Figueras, Daniela Cárdenas, Mariana Fernandez, B. Ruiz de Gauna, Mariona Rius, Teresa Cobo, R. García-Posadas, Sandra Hernàndez, Irene Teixidó, Enrique Barrau, Montse Palacio, Carmen Abad, Anna Knafel, Marcin Wiecheć, Agnieszka Nocuń, Anna Matyszkiewicz, Magdalena Juszczak, Ewa Wiercińska, Emilia Latała, M. Rodríguez, Pilar Prats, Ignacio Rodríguez, C. Comas, Anita J. Moon‐Grady, S. Christopher Derderian, Christine M. Jayme, Lily S. Cheng, Roberta L. Keller, Tippi C. MacKenzie, Mary Patrice Eastwood, Qing‐Yun Song, Xiaoping Jiang, Yu Jiang, Gang Ning, Taizhu Yang, O. Gómez, I. Soveral, M. Bennásar, F. Crispi, N. Masoller, E. Marimón, Joaquim Bartrons, E. Gratacós, Josep M. Martínez, Karl Oliver Kagan, Philipp Wagner, Jiri Sonek, Markus Hoopmann, Harald Abele, Sara Y. Brucker, Jan Deprest, Anouck Kampmeijer, Julio Jiménez, Silvia Zia, Rieta Vanbree, Godelieve Verbist, Jaan Toelen, Andrew Sharp, Kate Navaratnam, Patrícia Abreu, Žarko Alfirević, Peter Stone, Joana de Sousa, Vipul Upadhyay, Satz Mengensatzproduktion, Druckerei Stückle, Druckerei Stückle,

In the article by Rodriguez MA, Prats P, Rodriguez I, Comas C, entitled "Prenatal evaluation of the fetal conus medullaris on a routine scan" [Fetal Diagn Ther 2016;39:113–116, DOI: 10.1159/000441295], the following numbers in the first part of the Results section should be changed: "Among the final 606 (corrected to 696) cases included, 354 were evaluated by explorer A and 342 were evaluated by explorer B. The mean GA at the time of the ultrasound examination was 26.4 gestational weeks (range 20–35), ...

Tópico(s): Fetal and Pediatric Neurological Disorders

2016 - Karger Publishers | Fetal Diagnosis and Therapy