Sílvio Filipe, Laurent Itti, Luı́s A. Alexandre,
One of the major problems found when developing a 3D recognition system involves the choice of keypoint detector and descriptor. To help solve this problem, we present a new method for the detection of 3D keypoints on point clouds and we perform benchmarking between each pair of 3D keypoint detector and 3D descriptor to evaluate their performance on object and category recognition. These evaluations are done in a public database of real 3D objects. Our keypoint detector is inspired by the behavior ...
Tópico(s): Visual Attention and Saliency Detection
2014 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Image Processing
Michael Döhler, Edwin Reynders, Filipe Magalhães, Laurent Mevel, Guido De Roeck, Álvaro Cunha,
In Operational Modal Analysis (OMA) of large structures we often need to process sensor data from multiple nonsimultaneously recorded measurement setups. These setups share some sensors in common, the so-called reference sensors that are fixed for all the measurements, while the other sensors are moved from one setup to the next. To obtain the modal parameters of the investigated structure, it is necessary to process the data of all the measurement setups and normalize it as the unmeasured background ...
Tópico(s): Infrastructure Maintenance and Monitoring
2011 - Springer Nature | Conference proceedings of the Society for Experimental Mechanics
Filipe Marques, Laurent Falquet, Elke Vandewyer, Isabel Beets, Dominique A. Glauser,
In order to thrive in constantly changing environments, animals must adaptively respond to threatening events. Noxious stimuli are not only processed according to their absolute intensity, but also to their context. Adaptation processes can cause animals to habituate at different rates and degrees in response to permanent or repeated stimuli. Here, we used a forward genetic approach in Caenorhabditis elegans to identify a neuropeptidergic pathway, essential to prevent fast habituation and maintain ...
Tópico(s): Spaceflight effects on biology
2021 - Public Library of Science | PLoS Genetics
Produção Nacional
Revisado por pares
Stela Nhandeyara do Carmo Ramos, Amália Luísa Pedrosa Xavier, Filipe Simões Teodoro, Laurent Frédéric Gil, Leandro Vinícius Alves Gurgel,
This study describes, in detail, the chemical modification of sugarcane bagasse with phthalic anhydride to produce a carboxylate-functionalized sugarcane bagasse (SPA). The optimized modification conditions yielded SPA with a percent weight gain of 77.08% and an amount of carboxylic acid groups of 4.76 mmol/g. The SPA was characterized by PZC, FTIR, elemental analysis, TGA, and SEM-EDX. An SPA adsorbent was used to remove Co2+, Cu2+, and Ni2+ from aqueous solution in mono- and multicomponent systems ...
Tópico(s): Clay minerals and soil interactions
2015 - Elsevier BV | Industrial Crops and Products
Μαρία Τσολιά, Ariane Chapgier, P Taprantzi, Marina Servitzoglou, Ioannis Tassios, Nikolaos Spyridis, Fotini Papageorgiou, Orchidée Filipe Santos, Jean‐Laurent Casanova, Panayotis Spyridis,
Tópico(s): Immune Response and Inflammation
2006 - Springer Science+Business Media | European Journal of Pediatrics
Fabien Llambi, Filipe C. Lourenço, Devrim Gözüaçık, Catherine Guix, Laurent Pays, Gabriel del Rio, Adi Kimchi, Patrick Mehlen,
... papers by this author Author Information Fabien Llambi1, Filipe Calheiros Lourenço1, Devrim Gozuacik2, Catherine Guix1, Laurent Pays1, Gabriel Del Rio3, Adi Kimchi2 and Patrick ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2005 - Springer Nature | The EMBO Journal
Pierre Nahon, Marie Najean, Richard Layese, Kevin Zarca, Laeticia Blampain Segar, Carole Cagnot, Nathalie Ganne–Carrié, G. Nkontchou, Stanislas Pol, Cendrine Chaffaut, Fabrice Carrat, Maxime Ronot, Étienne Audureau, Isabelle Durand‐Zaleski, Pierre Nahon, Tarik Asselah, Dominique Guyader, Stanislas Pol, Hélène Fontaine, Georges‐Philippe Pageaux, Victor de Lédinghen, Denis Ouzan, Fabien Zoulim, Dominique Roulot, Albert Tran, Jean‐Pierre Bronowicki, Thomas Decaensi, Ghassan Riachi, Paul Calès, Jean‐Marie Péron, Laurent Alric, Marc Bourlière, Philippe Mathurin, Sébastien Dharancy, Jean–Frédéric Blanc, Armand Abergel, Olivier Chazouillères, Ariane Mallat, Jean‐Didier Grangé, P Attali, Louis d’Altéroche, Claire Wartelle, Thông Dao, Dominique Thabut, Christophe Pilette, Christine Silvain, Christos Christidis, Eric Nguyen‐Khac, Brigitte Bernard‐Chabert, Sophie Hillaire, Vincent Di Martino, Delphine Bonnet, Virginie Payssan-Sicart, Chloe Pomes, François Bailly, Marjolaine Beaudoin, Dominique Giboz, Kerstin Hartig-Lavie, M. Travis Maynard, Eric Billaud, D. Boutoille, Morane Cavellec, Marjorie Cheraud-Carpentier, Isabelle Hubert, Jaouad Benhida, Adrien Lannes, F. Lunel, F. Oberti, Nathalie Boyer, Nathalie Giuily, Corinne Castelnau, Giovanna Scoazec, Aziza Chibah, Sylvie Keser, Karim Bonardi, Anaïs Vallet‐Pichard, Philippe Sogni, Juliette Foucher, Jean‐Baptiste Hiriart, Amy C. Wilson, Sarah Shili, Faïza Chermak, Christelle Ansaldi, Nisserine Ben Amara, Laëtitia Chouquet, Emilie De Luca, Valérie Oulès, Rodolphe Anty, Ève Gelsi, Régine Truchi, Elena Luckina, Nadia Messaoudi, Joseph Moussali, Barbara De Dieuleveult, Damien Labarrière, Pascal Poter, Si Nafa Si Ahmed, Véronique Grando–Lemaire, Pierre Nahon, Valérie Bourcier, Séverine Brulé, Thomas Stalhberger, Caroline Jézéquel, Audrey Brener, Anne Laligant, Aline Rabot, Isabelle Renard, Thomas F. Baumert, Michel Doffoël, Catherine Schmidt‐Mutter, Pauline Simo‐Noumbissie, Esma Razi, Hélène Barraud, Mouni Bensenane, Abdelbasset Nani, Sarah Hassani-Nani, Marie-Albertine Bernard, Georges‐Philippe Pageaux, Michaël Bismuth, Ludovic Caillo, Stéphanie Faure, M.P. Ripault, Christophe Bureau, Jean Marie Péron, Marie Angèle Robic, Léa Tarallo, Marine Faure, Bruno Froissart, Marie‐Noëlle Hilleret, Jean–Pierre Zarski, Odile Goria, Victorien Grard, Hélène Montialoux, Muriel François, Christian Ouedraogo, Christelle Pauleau, Anne Varault, Tony Andréani, Bénédicte Angoulevant, Azeline Chevance, Lawrence Serfaty, Térésa Antonini, Audrey Coilly, Jean‐Charles Duclos Vallée, Mariagrazia Tateo, Christophe Bonny, Chanteranne Brigitte, Géraldine Lamblin, Léon Muti, Abdenour Babouri, Virginie Filipe, Camille Barrault, Laurent Costes, Hervé Hagège, Soraya Merbah, Paul Carrier, Maryline Debette‐Gratien, Jérémie Jacques, Guillaume Lassailly, Florent Artu, V. Canva, Sébastien Dharancy, Alexandre Louvet, Marianne Latournerie, Marc Bardou, Thomas Mouillot, Yannick Bacq, Didier Barbereau, Charlotte Nicolas, Caroline Chevalier, Isabelle Archambeaud, Sarah Habès, Nisserine Ben Amara, Danièle Botta-Fridlund, Eric Saillard, Marie-Josée Lafrance, Marc Bourlière, P. Cacoub, Fabrice Carrat, Patrizia Carrieri, Elisabeth Delarocque‐Astagneau, Victor de Lédinghen, Céline Dorival, Jean Dubuisson, Hélène Fontaine, Chantal Housset, Dominique Larrey, Patrick Marcellin, Philippe Mathurin, Pierre Nahon, Georges‐Philippe Pageaux, Jean‐Michel Pawlotsky, Ventzislava Petrov–Sanchez, Stanislas Pol, Sophie Vaux, Linda Wittkop, Yazdan Yazdanpanah, Jean–Pierre Zarski, Fabien Zoulim, Jessica Zucman‐Rossi, Nathalie Ganne–Carrié, Cendrine Chaffaut, Isabelle Archambeaud, Louis d’Altéroche, F. Oberti, Dominique Roulot, Christophe Moreno, Alexandre Louvet, Thông Dao, Romain Moirand, Odile Goria, Eric Nguyen‐Khac, Nicolas Carbonell, Jean-Charles Duclos-Vallée, Stanislas Pol, Victor de Lédinghen, Violaine Ozenne, Jean Henrion, Jean‐Marie Péron, Albert Tran, Gabriel Perlemuter, Xavier Amiot, Jean–Pierre Zarski, Sylvie Chevret,
Reinforced hepatocellular carcinoma (HCC) surveillance using magnetic resonance imaging (MRI) could increase early tumour detection but faces cost-effectiveness issues. In this study, we aimed to evaluate the cost-effectiveness of MRI for the detection of very early HCC (Barcelona Clinic Liver Cancer [BCLC] 0) in patients with an annual HCC risk >3%.French patients with compensated cirrhosis included in 4 multicentre prospective cohorts were considered. A scoring system was constructed to identify patients ...
Tópico(s): Liver Disease and Transplantation
2021 - Elsevier BV | JHEP Reports
Filipe Correia Martins, Dominique‐Laurent Couturier, Inês de Santiago, Carolin M. Sauer, Maria Vias, Mihaela Angelova, Deborah A. Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa S. Carnevalli, Barry R. Davies, Thomas B.K. Watkins, Ionut G. Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew Eldridge, Bristi Basu, Mercedes Jimenez‐Liñan, Andrew McPherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P. Shah, Iain A. McNeish, Carlos Caldas, Gérard I. Evan, Charles Swanton, James D. Brenton,
Chromosomal instability is a major challenge to patient stratification and targeted drug development for high-grade serous ovarian carcinoma (HGSOC). Here we show that somatic copy number alterations (SCNAs) in frequently amplified HGSOC cancer genes significantly correlate with gene expression and methylation status. We identify five prevalent clonal driver SCNAs (chromosomal amplifications encompassing MYC, PIK3CA, CCNE1, KRAS and TERT) from multi-regional HGSOC data and reason that their strong ...
Tópico(s): PARP inhibition in cancer therapy
2022 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Filipe Correia Martins, Dominique‐Laurent Couturier, Anna Paterson, Anthony N. Karnezis, Christine Chow, Tayyebeh M. Nazeran, Adekunle Odunsi, Aleksandra Gentry‐Maharaj, Aleksandra Vrvilo, Alexander Hein, Aline Talhouk, Ana Osório, Andreas D. Hartkopf, Angela Brooks‐Wilson, Anna deFazio, Anna Fischer, Arndt Hartmann, Brenda Y. Hernandez, Bryan M. McCauley, Chloe Karpinskyj, Christiani Bisinoto de Sousa, Claus Høgdall, Daniel Guimarães Tiezzi, Esther Herpel, Florin‐Andrei Taran, Francesmary Modugno, Gary L. Keeney, Gregg Nelson, Helen Steed, Honglin Song, Hugh Luk, Javier Benı́tez, Jennifer Alsop, Jennifer M. Koziak, Jenny Lester, Joseph H. Rothstein, Jurandyr Moreira de Andrade, Lene Lundvall, Luis Paz‐Ares, Luis A. Díaz‐Robles, Lynne R. Wilkens, María J. García, Maria P. Intermaggio, Marie-Lyne Alcaraz, Mary Anne Brett, Matthias W. Beckmann, Mercedes Jimenez‐Liñan, Michael S. Anglesio, Michael E. Carney, Michael Schneider, Nadia Traficante, Nadja Pejovic, Naveena Singh, Nhu D. Le, Hans‐Peter Sinn, Prafull Ghatage, Ramona Erber, Robert P. Edwards, Robert A. Vierkant, Roberta B. Ness, Samuel Leung, Sandra Oršulić, Sara Y. Brucker, Scott H. Kaufmann, Sián Fereday, Simon A. Gayther, Stacey J. Winham, Stefan Kommoss, Tanja Pejović, Teri A. Longacre, Valerie McGuire, Valerie Rhenius, Weiva Sieh, Yurii B. Shvetsov, Alice S. Whittemore, Annette Staebler, Beth Y. Karlan, Cristina Rodríguez‐Antona, David D.L. Bowtell, Ellen L. Goode, Estrid Høgdall, Francisco José Cândido dos Reis, Jacek Gronwald, Jenny Chang‐Claude, Kirsten B. Moysich, Linda E. Kelemen, Linda S. Cook, Marc T. Goodman, Peter A. Fasching, Robin Crawford, Suha Deen, Usha Menon, David G. Huntsman, Martin Köbel, Susan J. Ramus, Paul D.P. Pharoah, James D. Brenton,
PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous (LGSOC)). We aimed to characterise PTEN expression as a biomarker in epithelial ovarian cancer in a large population-based study.
Tópico(s): Renal Diseases and Glomerulopathies
2020 - Springer Nature | British Journal of Cancer
Arnaud Estoup, Stuart J. E. Baird, Nicolas Ray, Mathias Currat, Jean‐Marie Cornuet, Filipe Santos, Mark Beaumont, Laurent Excoffier,
We developed a spatially explicit model of a bioinvasion and used an approximate Bayesian computation (ABC) framework to make various inferences from a combination of genetic (microsatellite genotypes), historical (first observation dates) and geographical (spatial coordinates of introduction and sampled sites) information. Our method aims to discriminate between alternative introduction scenarios and to estimate posterior densities of demographically relevant parameters of the invasive process. The ...
Tópico(s): Animal Ecology and Behavior Studies
2010 - Wiley | Molecular Ecology Resources
Pierre Génin, Frédérique Cuvelier, Sandrine Lambin, Josina Filipe, Elodie Autrusseau, Christine Laurent, Emmanuel Laplantine, Robert Weil,
Viral invasion into a host is initially recognized by the innate immune system, mainly through activation of the intracellular cytosolic signaling pathway and coordinated activation of interferon regulatory factor 3 (IRF3) and nuclear factor kappa B (NF-κB) transcription factors that promote type I interferon gene induction. The TANK-binding Kinase 1 (TBK1) phosphorylates and activates IRF3. Here, we show that Optineurin (Optn) dampens the antiviral innate immune response by targeting the deubiquitinating ...
Tópico(s): Immune Response and Inflammation
2015 - Public Library of Science | PLoS Pathogens
Alexis Brenes, Jérôme Juillard, Laurent Bourgois, Filipe Vinci dos Santos,
This paper deals with the influence of the shape of the driving waveform on the frequency responses of microelectromechanical systems (MEMS) resonators under nonlinear actuation. Our models show that, at large oscillation amplitudes, these responses are strongly dependent on the shape of the actuation waveform so that the nonlinear frequency response is not the system signature, but the system signature under a specific driving waveform. The case of a MEMS resonator electrostatically driven with ...
Tópico(s): Acoustic Wave Resonator Technologies
2016 - Institute of Electrical and Electronics Engineers | Journal of Microelectromechanical Systems
Michel Cathelineau, Marie‐Christine Boiron, Christian Marignac, Maxime Dour, Mélanie Dejean, Eleonora Carocci, Laurent Truche, Filipe Pinto,
The Variscan vein-type Panasqueira W-Sn(Cu) deposit, one of the main tungsten deposits in Western Europe, has a long and complicated geological history. The first vein infillings, which consist of the quartz-wolframite association as well as the first generation of topaz, underwent significant deformation. As a consequence, most fluid inclusions of the earliest hydrothermal event are deformed and destroyed. Two preserved fluid inclusion assemblages are, however, found in the topaz overgrowth band ...
Tópico(s): High-pressure geophysics and materials
2020 - Elsevier BV | Ore Geology Reviews
Mikkel‐Holger S. Sinding, Shyam Gopalakrishnan, Jazmín Ramos‐Madrigal, Marc de Manuel, Vladimir V. Pitulko, Lukas F. K. Kuderna, Tatiana R. Feuerborn, Laurent Frantz, Filipe Garrett Vieira, Jonas Niemann, José Alfredo Samaniego Castruita, Christian Carøe, Emilie Andersen-Ranberg, Peter Jordan, Elena Y. Pavlova, Pavel A. Nikolskiy, Aleksei Kasparov, Varvara V. Ivanova, Eske Willerslev, Pontus Skoglund, Merete Fredholm, Sanne Eline Wennerberg, Mads Peter Heide‐Jørgensen, Runé Dietz, Christian Sonne, Morten Meldgaard, Love Dalén, Greger Larson, Bent Petersen, Thomas Sicheritz‐Pontén, Lutz Bachmann, Øystein Wiig, Tomás Marquès‐Bonet, Anders J. Hansen, M. Thomas P. Gilbert,
Sled dog arctic adaptations go far back Dogs have been used for sledding in the Arctic as far back as ∼9500 years ago. However, the relationships among the earliest sled dogs, other dog populations, and wolves are unknown. Sinding et al. sequenced an ancient sled dog, 10 modern sled dogs, and an ancient wolf and analyzed their genetic relationships with other modern dogs. This analysis indicates that sled dogs represent an ancient lineage going back at least 9500 years and that wolves bred with the ...
Tópico(s): Pleistocene-Era Hominins and Archaeology
2020 - American Association for the Advancement of Science | Science
Produção Nacional
Revisado por pares
Bruno Christiano Silva Ferreira, Filipe Simões Teodoro, Aparecida Barbosa Mageste, Laurent Frédéric Gil, Rossimiriam Pereira de Freitas, Leandro Vinícius Alves Gurgel,
A new carboxylate-functionalized sugarcane bagasse (SMA) was prepared via a solvent-free procedure involving esterification of sugarcane bagasse with Meldrum's acid. The optimized conditions provided SMA with a percent weight gain of 86.0% and 4.69 ± 0.20 mmol/g of carboxylic acid groups. SMA was characterized by FTIR, TGA, elemental analysis and SEM. Kinetic experiments showed that the amount of crystal violet adsorbed increased with increasing temperature and equilibrium was reached at 12 h. Adsorption ...
Tópico(s): Minerals Flotation and Separation Techniques
2014 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Revisado por pares
Filipe Simões Teodoro, Oscar Fernando Herrera Adarme, Laurent Frédéric Gil, Leandro Vinícius Alves Gurgel,
In the second part of this series of studies, the competitive adsorption of three binary systems Cu2+–Co2+, Cu2+–Ni2+ and Co2+–Ni2+ on a carboxylated cellulose derivative (CTA) was evaluated in binary equimolar (1:1) metal–ion aqueous solutions. Bicomponent adsorption studies were developed as a function of contact time and initial metal ion concentration. Bicomponent adsorption kinetic data was modeled by monocomponent kinetic models of pseudo-first- (PFO) and pseudo-second-order (PSO) and a competitive ...
Tópico(s): Extraction and Separation Processes
2016 - Elsevier BV | Journal of Colloid and Interface Science
Carolina Prando, Arina Samarina, Jacinta Bustamante, Stéphanie Boisson‐Dupuis, Aurélie Cobat, Capucine Pïcard, Zubaida Al‐Sum, Suliman Aljumaah, Sami Al-Hajjar, Husn H. Frayha, Abdullah Alangari, Hamoud Al‐Mousa, Khalid Mobaireek, Imen Ben‐Mustapha, Parvaneh Adimi, J. Feinberg, Maylis de Suremain, Laurent Jannière, Orchidée Filipe‐Santos, Nahal Mansouri, Stephan Jl, R. Nallusamy, D S Kumararatne, Mohamad Reza Bloorsaz, M. Ben-Ali, Houda Elloumi‐Zghal, Jalel Chemli, Jihène Bouguila, Mohamed Béjaoui, Emadia Alaki, Tariq AlFawaz, Eman Al Idrissi, Gehad ElGhazali, Andrew J. Pollard, B Murugasu, B W Lee, Rabih Halwani, Mofareh AlZahrani, Mohammed Al Shehri, Ibrahim Bin-Hussain, Seyed Alireza Mahdaviani, Nima Parvaneh, Laurent Abel, Davood Mansouri, Mohamed‐Ridha Barbouche, Saleh Al‐Muhsen, Jean‐Laurent Casanova,
Tópico(s): Whipple's Disease and Interleukins
2013 - Wolters Kluwer | Medicine
Filipe Vasconcelos, Sylvain Cristol, Jean‐François Paul, Laurent Delevoye, Francesco Mauri, Thibault Charpentier, G. Le Caër,
The extended Czjzek model (ECM) is applied to the distribution of NMR parameters of a simple glass model (sodium metaphosphate, NaPO3) obtained by molecular dynamics (MD) simulations. Accurate NMR tensors, electric field gradient (EFG) and chemical shift anisotropy (CSA) are calculated from density functional theory (DFT) within the well-established PAW/GIPAW framework. The theoretical results are compared to experimental high-resolution solid-state NMR data and are used to validate the considered structural ...
Tópico(s): NMR spectroscopy and applications
2013 - IOP Publishing | Journal of Physics Condensed Matter
Guillaume Girard, Filipe Vasconcelos, Lionel Montagne, Laurent Delevoye,
The present study has investigated the structure of four niobium phosphates compounds using 31P MAS NMR spectroscopy. Niobium 93Nb decoupling, applied during 31P NMR acquisition led to a resolution enhancement by a factor of 2–3, which allowed distinguish phosphorous sites separated by 1 ppm or less. The assignment of 31P spectra has been completed by use of first-principles calculations derived from the original XRD structures. One of the compounds, Na3.04Nb7P4O29, contains a sodium vacancy, clearly ...
Tópico(s): Solid-state spectroscopy and crystallography
2017 - Elsevier BV | Solid State Nuclear Magnetic Resonance
Jin Huang, Anne Filipe, Cécile Rahuel, Philippe Bonnin, Laurent Mesnard, Coralie L. Guérin, Yu Wang, Caroline Le Van Kim, Yves Colin, Pierre‐Louis Tharaux,
Migration of circulating leukocytes from the vasculature into the surrounding tissue is an important component of the inflammatory response. Among the cell surface molecules identified as contributing to leukocyte extravasation is VCAM-1, expressed on activated vascular endothelium, which participates in all stages of leukocyte-endothelial interaction by binding to leukocyte surface expressed integrin VLA-4. However, not all VLA-4-mediated events can be linked to VCAM-1. A novel interaction between ...
Tópico(s): Reproductive System and Pregnancy
2014 - Elsevier BV | Kidney International
H. Seznec, Delphine Simon, Laurent Monassier, Paola Criqui-Filipe, Anne Gansmüller, Pierre Rustin, Michel Kœnig, Hélène Puccio,
Friedreich ataxia (FRDA), a progressive neurodegenerative disorder associated with cardiomyopathy, is caused by severely reduced frataxin, a mitochondrial protein involved in Fe-S cluster assembly. We have recently generated mouse models that reproduce important progressive pathological and biochemical features of the human disease. Our frataxin-deficient mouse models initially demonstrate time-dependent intramitochondrial iron accumulation, which occurs after onset of the pathology and after inactivation ...
Tópico(s): Parkinson's Disease Mechanisms and Treatments
2004 - Oxford University Press | Human Molecular Genetics
Aideen Foley, Daniela Dalmonech, A. D. Friend, Filipe Aires, A. T. Archibald, Patrick J. Bartlein, Laurent Bopp, J. Chappellaz, Peter M. Cox, Neil R. Edwards, Georg Feulner, Pierre Friedlingstein, Sandy P. Harrison, Peter O. Hopcroft, Chris Jones, Jana Kolassa, J. G. Levine, I. Colin Prentice, J. A. Pyle, Natalia Vázquez Riveiros, Eric Wolff, Sönke Zaehle,
Abstract. Earth system models (ESMs) are increasing in complexity by incorporating more processes than their predecessors, making them potentially important tools for studying the evolution of climate and associated biogeochemical cycles. However, their coupled behaviour has only recently been examined in any detail, and has yielded a very wide range of outcomes. For example, coupled climate–carbon cycle models that represent land-use change simulate total land carbon stores at 2100 that vary by ...
Tópico(s): Climate variability and models
2013 - Copernicus Publications | Biogeosciences
Virginie Filipe, Patrick B. Allen, Laurent Peyrin‐Biroulet,
The self-prescribing rates of corticosteroids in inflammatory bowel disease (IBD) patients treated with biologicals are unknown.To investigate the frequency and modalities of self-medication with steroids in adult IBD patients.Patients with IBD who attended Nancy University Hospital between November 2012 and May 2013 were included in the study. Patients were interviewed using an 11 item questionnaire.100 patients participated in the survey. In total 15 patients (15%) had already used corticosteroids ...
Tópico(s): Gastrointestinal motility and disorders
2015 - Elsevier BV | Digestive and Liver Disease
Produção Nacional
Revisado por pares
Stela Nhandeyara do Carmo Ramos, Amália Luísa Pedrosa Xavier, Filipe Simões Teodoro, Megg Madonyk Cota Elias, Fernanda Goncalves, Laurent Frédéric Gil, Rossimiriam Pereira de Freitas, Leandro Vinícius Alves Gurgel,
A new carboxylated-functionalized sugarcane bagasse (STA) was prepared through the esterification of sugarcane bagasse with trimellitic anhydride. The optimized synthesis conditions yield STA with a percent weight gain of 73.9% and the number of carboxylic acid groups accounted for 3.78 mmol/g. STA was characterized by FTIR, elemental analysis, TGA, PZC, and SEM. Adsorption kinetics followed a pseudo-second-order model. The adsorption rate constant showed the following order: k2,Ni2+ > k2,Cu2+ > k2,Co2+. ...
Tópico(s): Extraction and Separation Processes
2015 - Elsevier BV | Industrial Crops and Products
Claire Fieschi, Marita Bosticardo, Ludovic de Beaucoudrey, Stéphanie Boisson‐Dupuis, Jacqueline Feinberg, Orchidée Filipe Santos, Jacinta Bustamante, Jacov Levy, Fabio Candotti, Jean‐Laurent Casanova,
Complete interleukin-12/interleukin-23 receptor beta1 (IL-12Rbeta1) deficiency is the most frequent known genetic etiology of the syndrome of Mendelian susceptibility to mycobacterial disease. The patients described to date lack IL-12Rbeta1 at the surface of their natural killer (NK) and T cells due to IL12RB1 mutations, which either interrupt the open reading frame or disrupt protein folding. We describe a patient with a large in-frame deletion of 12165 nucleotides (nt) in IL12RB1, encompassing exons ...
Tópico(s): T-cell and B-cell Immunology
2004 - Elsevier BV | Blood
Eleonora Carocci, Christian Marignac, Michel Cathelineau, Laurent Truche, Andreï Lecomte, Filipe Pinto,
Abundant W-rich rutile in the tourmalinized wall-rocks from the Panasqueira W-deposit appears to be a marker of the onset of the main wolframite depositing event. Rutile displays spectacular zoning, both sector (SZ) and oscillatory (OZ). An extensive set of compositional data obtained on crystals, beforehand studied using back-scattered electron images and X-ray maps, was used to address (i) the effects of SZ on differential trapping of minor elements, and (ii) the significance of the OZ in deciphering ...
Tópico(s): High-pressure geophysics and materials
2018 - Multidisciplinary Digital Publishing Institute | Minerals
Jacinta Bustamante, Güzide Aksu, Guillaume Vogt, Ludovic de Beaucoudrey, Ferah Genel, Ariane Chapgier, Orchidée Filipe‐Santos, Jacqueline Feinberg, Jean‐François Emile, Necil Kütükçüler, Jean‐Laurent Casanova,
A few known primary immunodeficiencies confer predisposition to clinical disease caused by weakly virulent mycobacteria, such as BCG vaccines (regional disease, known as BCG-itis, or disseminated disease, known as BCG-osis), or more virulent mycobacteria, such as Mycobacterium tuberculosis (pulmonary and disseminated tuberculosis). We investigated the clinical and genetic features of a 12-year-old boy with both recurrent BCG-osis and disseminated tuberculosis. The patient's phagocytic cells produced ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2007 - Elsevier BV | Journal of Allergy and Clinical Immunology
Filipe Marques, Gabriella Sarò, Andrei-Stefan Lia, Richard J. Poole, Laurent Falquet, Dominique A. Glauser,
Understanding how the nervous system bridges sensation and behavior requires the elucidation of complex neural and molecular networks. Forward genetic approaches, such as screens conducted in C. elegans, have successfully identified genes required to process natural sensory stimuli. However, functional redundancy within the underlying neural circuits, which are often organized with multiple parallel neural pathways, limits our ability to identify 'neural pathway-specific genes', i.e. genes that are ...
Tópico(s): Genetics, Aging, and Longevity in Model Organisms
2019 - Public Library of Science | PLoS Genetics
Produção Nacional
Revisado por pares
Renata Aparecida Fideles, Filipe Simões Teodoro, Amália Luísa Pedrosa Xavier, Oscar Fernando Herrera Adarme, Laurent Frédéric Gil, Leandro Vinícius Alves Gurgel,
In the second part of this series of studies, the bicomponent adsorption of safranin-T (ST) and auramine-O (AO) on trimellitated sugarcane bagasse (STA) was evaluated using equimolar dye aqueous solutions at two pH values. Bicomponent batch adsorption was investigated as a function of contact time, solution pH and initial concentration of dyes. Bicomponent kinetic data were fitted by the pseudo-first-order and pseudo-second-order models and the competitive model of Corsel. Bicomponent equilibrium data ...
Tópico(s): Electrostatics and Colloid Interactions
2019 - Elsevier BV | Journal of Colloid and Interface Science
Pierre Génin, Frédérique Cuvelier, Sandrine Lambin, Josina Filipe, Elodie Autrusseau, Christine Laurent, Emmanuel Laplantine, Robert Weil,
There is an error in the first sentence and fourth paragraph of the Introduction. The following sentence is incorrect: Optineurin (tineurin (TE.DATA the MAVS-TRAOptn), also called NRP (NEMO-related protein) or FIP-2 (adenovirus E3-14.7K-interacting protein) exhibits 53% of sequence similarities with NEMO [28, 29]. The correct sentence is: Optineurin (“optic neuropathy inducing” or Optn), also called NRP (NEMO-related protein) or FIP-2 (adenovirus E3-14.7K-interacting protein) is closely related to NEMO with ...
Tópico(s): Neutrophil, Myeloperoxidase and Oxidative Mechanisms
2015 - Public Library of Science | PLoS Pathogens