Produção Nacional
Revisado por pares
Sérgio Henrique Godinho Silva, Phillip Owens, Bruno Montoani Silva, Geraldo César de Oliveira, Michele Duarte de Menezes, Leandro Campos Pinto, Nilton Curi,
In soil surveys, the number of collected samples is commonly reduced by factors that hamper field activities, such as rugged terrain and lack of roads. Conditioned Latin hypercube (CLH) sampling has been used to properly capture soil variability across the landscape, whereas cost-constrained conditioned Latin hypercube (CCLH) sampling limits the sampling to areas of easy access. The objectives of this work were to: (i) compare the efficiency of CLH and CCLH sampling systems to create soil maps, considering ...
Tópico(s): Soil Carbon and Nitrogen Dynamics
2015 - Wiley | Soil Science Society of America Journal
Produção Nacional
Revisado por pares
Léo Fernandes Ávila, Carlos Rogério de Mello, Leandro Campos Pinto, Antônio Marciano da Silva,
http://dx.doi.org/10.5902/1980509815739A análise do comportamento da precipitação e sua interação nas diferentes etapas do ciclo hidrológico em bacias hidrográficas florestadas são essenciais para a determinação do balanço hídrico, devido à sua relevante participação nos processos hidrológicos e à sua variação espaço-temporal em função de fatores edáficos, topográficos, climáticos e de vegetação. Devido à heterogeneidade da Mata Atlântica, aliada à variabilidade espaço-temporal da precipitação, ...
Tópico(s): Geography and Environmental Studies
2014 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Florestal
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, Léo Fernandes Ávila,
Maintaining the quality of water resources is of great importance for environmental preservation and the quality of life of consumers, and is one of the greatest challenges facing humanity today. Land-use for agriculture and animal farming significantly changes the biological, physical and chemical characteristics of natural systems. This study comprised monitoring of two subbasins located in the Mantiqueira Range region, from which water samples were collected on a monthly basis between June 2010 ...
Tópico(s): Geography and Environmental Studies
2013 - UNIVERSIDADE FEDERAL DE LAVRAS | CERNE
Carolina Marques Miranda, Mariana de Lima Isaac Leandro Campos, Hugo Leite‐Almeida,
Obesity has been associated with increased chronic pain susceptibility but causes are unclear. In this review, we systematize and analyze pain outcomes in rodent models of obesity as these can be important tools for mechanistic studies. Studies were identified using MEDLINE/PubMed and Scopus databases using the following search query: (((pain) OR (nociception)) AND (obesity)) AND (rat OR (mouse) OR (rodent))). From each eligible record we extracted the following data: species, strain, sex, pain/obesity ...
Tópico(s): Exercise and Physiological Responses
2021 - Elsevier BV | Neurobiology of Pain
Produção Nacional
Revisado por pares
Sérgio Henrique Godinho Silva, David C. Weindorf, Leandro Campos Pinto, Wilson Missina Faria, Fausto Weimar Acérbi Júnior, Lucas Rezende Gomide, José Márcio de Mello, Alceu Linares de Pádua, Igor Alexandre de Souza, Anita Fernanda dos Santos Teixeira, Luiz Roberto Guimarães Guilherme, Nilton Curi,
Soil texture is an important feature in soil characterization, although its laboratory determination is costly and time-consuming. As an alternative, this study aimed at predicting soil texture from portable X-ray fluorescence (pXRF) spectrometry data in Brazilian soils. 1565 soil samples (503 from superficial and 1062 from subsuperficial horizons) were analyzed in the laboratory for soil texture and scanned with the pXRF. Elemental contents determined by pXRF were correlated with soil texture and ...
Tópico(s): Clay minerals and soil interactions
2019 - Elsevier BV | Geoderma
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, L. D. Norton, Phillip Owens, Nilton Curi,
Tópico(s): Groundwater and Watershed Analysis
2016 - Elsevier BV | CATENA
Produção Nacional
Revisado por pares
Carlos Rogério de Mello, L. D. Norton, Leandro Campos Pinto, Samuel Beskow, Nilton Curi,
ABSTRACT Models have been used by man for thousands of years to control his environment in a favorable way to better human living conditions. The use of hydrologic models has been a widely effective tool in order to support decision makers dealing with watersheds related to several economic and social activities, like public water supply, energy generation, and water availability for agriculture, among others. The purpose of this review is to briefly discuss some models on soil and water movement ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2016 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, Phillip Owens, L. D. Norton, Nilton Curi,
Mantiqueira Range is the most important headwater region in southeastern Brazil, being responsible for streamflows that feed a significant part of Brazilian hydroelectric energy production. This region is extremely fragile with endemic species like those that compose the upper mountain cloud forest (UMCF), and the dominant soils are typical Inceptisols. These forest environments are rapidly disappearing in Brazil. The changing land use combined with shallow Inceptisols lead to important effects on ...
Tópico(s): Groundwater and Watershed Analysis
2015 - American Society of Civil Engineers | Journal of Hydrologic Engineering
Produção Nacional
Revisado por pares
Alba Lucia Araujo Skorupa, Sérgio Henrique Godinho Silva, Giovana Clarice Pôggere, Diego Tassinari, Leandro Campos Pinto, Yuri Lopes Zinn, Nilton Curi,
Soils result from the interaction of five independent formation factors. If one factor varies, while the others remain constant, different soils can be produced. Herein, we demonstrated an opposing trend, wherein two soils were similar, despite considerable differences in all factors of soil formation. We sampled two Inceptisols (Oxic Dystrudepts) formed on different parent materials (gneiss vs. mica schist), climate (tropical altimontane vs. warmer, drier plateau), topography (1 650 m, 45% slope vs. ...
Tópico(s): Soil and Unsaturated Flow
2017 - Elsevier BV | Pedosphere
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, L. D. Norton, Giovana Clarice Pôggere, Phillip Owens, Nilton Curi,
The Mantiqueira Range region is one of the most important headwaters in southeastern Brazil. In this context, the relationship between pedology and hydrology has been debated and analyzed in recent years, contributing to the creation of a multidisciplinary science call hydropedology. Therefore, the aim of this study was to evaluate the hydropedological properties of a mountainous Clayey Humic Dystrudept in the Mantiqueira Range region, in the state of Minas Gerais, Brazil, comparing two land-uses, ...
Tópico(s): Soil Management and Crop Yield
2017 - UNIVERSIDADE DE SÃO PAULO | Scientia Agricola
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Carlos Rogério de Mello, L. D. Norton, Sérgio Henrique Godinho Silva, Luís Renato Silva Taveira, Nilton Curi,
ABSTRACT In Brazil, the Mantiqueira Range, southeastern region, shelters the last remnants of the ecologically important Upper Montane Tropical Forest. since extensive exploration that has been taking place in this biome for decades, the influence of land-use changes on hydropedology in these areas must be investigated once major land-use changes have been observed. This study aims to evaluate the land-use influence on soil drainable porosity (SDP) in a headwater watershed located in the Mantiqueira ...
Tópico(s): Hydrology and Watershed Management Studies
2017 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Leandro Campos Pinto, Yuri Lopes Zinn, Carlos Rogério de Mello, Phillip Owens, L. D. Norton, Nilton Curi,
ABSTRACTUnderstanding soil formation processes across different landscapes is needed to predict how soil properties will respond to land use change. This study aimed to characterize mountainous Inceptisols (Cambisols) under high altitude subtropical climate in southeastern Brazil, by soil physical, chemical and micromorphological analyses, under native forest and pasture. The soil under pasture had a greater bulk density than under forest, resulting in a severe reduction of macroporosity. At two ...
Tópico(s): Soil and Unsaturated Flow
2015 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Marcelo Gomes Davanço, Anna Caroline Campos Aguiar, Leandro Alves dos Santos, Elias Carvalho Padilha, Michel Leandro de Campos, Cléverton Roberto de Andrade, Luiz Marcos da Fonseca, Jean Leandro dos Santos, Chung Man Chin, Antoniana U. Krettli, Rosângela Gonçalves Peccinini,
Plasmodium vivax is the most prevalent of the five species causing malaria in humans. The current available treatment for P. vivax malaria is limited and unsatisfactory due to at least two drawbacks: the undesirable side effects of primaquine (PQ) and drug resistance to chloroquine. Phenylalanine-alanine-PQ (Phe-Ala-PQ) is a PQ prodrug with a more favorable pharmacokinetic profile compared to PQ. The toxicity of this prodrug was evaluated in in vitro assays using a human hepatoma cell line (HepG2), ...
Tópico(s): Traditional and Medicinal Uses of Annonaceae
2014 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Iã Ferreira Miranda, Catiane Souza, Alexandre Tavares Schneider, Leandro Campos Chagas, Jefferson Fagundes Loss,
There is some evidence in the literature about the effectiveness of the Pilates methods in the low back pain. Moreover, Pilates focus on exercises that empathizes the stability and/or mobility of the spine. Therefore, it is discussed in the literature whether higher levels of stability or mobility of the lumbar spine generates better results, both in performance and rehabilitation for low back pain.Compare the effects of the low back mobility and stability exercises from Pilates Method on low back ...
Tópico(s): Spine and Intervertebral Disc Pathology
2017 - Elsevier BV | Complementary Therapies in Clinical Practice
Produção Nacional
Revisado por pares
Virgínia F. Braga, Giselle Camargo Mendes, Raphael T.R. Oliveira, Carla Q.G. Soares, Cristiano F. Resende, Leandro Campos Pinto, Reinaldo de Santana, Lyderson Fácio Viccini, Nádia Rezende Barbosa Raposo, Paulo Henrique Pereira Peixoto,
This work describes an efficient micropropagation protocol for Verbena litoralis and the study of the antinociceptive and antioxidant activities in extracts of this species. For the establishment in vitro, surface-sterilization procedures and PVPP showed high efficiency in fungal-bacterial contamination and phenol oxidation controls. Nodal segments cultivation in MS medium supplemented with 6-benzyladenine (7.5 µM)/α-naphthaleneacetic acid (NAA; 0.005 µM) induced multiple shoots. Elongated shoots ...
Tópico(s): Botany, Ecology, and Taxonomy Studies
2012 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Juliana Silva, Victoria Monge‐Fuentes, Flávia Gomes, Kamila Soares Lopes, Lilian Carneiro dos Anjos, Gabriel Avohay Alves Campos, Claudia Arenas, Andréia Biolchi Mayer, Jacqueline Coimbra Gonçalves, Priscilla Galante, Leandro Ambrósio Campos, Márcia Renata Mortari,
Neurodegenerative diseases are relentlessly progressive, severely impacting affected patients, families and society as a whole. Increased life expectancy has made these diseases more common worldwide. Unfortunately, available drugs have insufficient therapeutic effects on many subtypes of these intractable diseases, and adverse effects hamper continued treatment. Wasp and bee venoms and their components are potential means of managing or reducing these effects and provide new alternatives for the ...
Tópico(s): Insect and Pesticide Research
2015 - Multidisciplinary Digital Publishing Institute | Toxins
Produção Nacional
Wantuir Filipe Teixeira Chagas, Douglas Ramos Guelfi Silva, Jordana Reis Lacerda, Leandro Campos Pinto, André Baldansi Andrade, Valdemar Faquin,
The application of urea in coffee crop has caused high losses of nitrogen (N) by volatilization, causing the low use and recovery of this nutrient. This low use of N may interfere in the growth and nutrition of the coffee crop and thus, influence the efficiency of the nitrogen fertilization. The aim of this work was to assess the growth, nutritional and physiological characteristics and the agronomic efficiency of the nitrogen fertilization with different nitrogen fertilizer technologies. The experiment ...
Tópico(s): Growth and nutrition in plants
2019 - UNIVERSIDADE FEDERAL DE LAVRAS | Coffee Science
Produção Nacional
Anderson Leandro Peres Campos, Lourenço Santos Del Ponte, Adriana Schüler Cavalli, Mariângela da Rosa Afonso, Jose Franscisco Schild, Felipe Fossati Reichert,
Training programs that include aerobics and strength exercises, either at the same session or alternate days are defined as concurrent training (CT). The objective of this study was to verify the effects of a CT program on biochemical parameters,cardiovascular fitness, body composition and neuromuscular aspects. Twenty two elderly women physically active were randomly allocated to one of the five groups: AS (aerobic exercises followed by strength training; n=5), SA (strength activities followed by ...
Tópico(s): Physical Activity and Health
2013 - UNIVERSIDADE FEDERAL DE SANTA CATARINA | Brazilian Journal of Kinanthropometry and Human Performance
Produção Nacional
Revisado por pares
Reuber Albuquerque Brandão, Ulisses Caramaschi, Wilian Vaz Silva, Leandro Ambrósio Campos,
Based on the analyses of specimens collected at several areas in the Cerrado domain from Central Brazil and others housed in scientific collections and on specimens collected at the type-locality, herein we describe three new species belonging to the P. cristiceps group: Proceratophrys bagnoi sp. nov., from UHE Serra da Mesa power plant (13°49’47.5”S, 48°19’17”W; 570 m a.s.l.; WGS84 datum), Municipality of Minaçu, State of Goiás; Proceratophrys branti sp. nov., from Jalapão, Municipality of Mateiros ( ...
Tópico(s): Fish biology, ecology, and behavior
2013 - Q15088586 | Zootaxa
Produção Nacional
Revisado por pares
B. C. L. Dias, Mariana Millan Fachi, Michel Leandro de Campos, Flávia Lada Degaut Degaut, Rosângela Gonçalves Peccinini, Roberto Pontarolo,
Abstract Monitoring the plasma concentrations of metformin and sodium‐glucose cotransporter‐2 inhibitors (canagliflozin, dapagliflozin and empagliflozin) is essential for pharmacokinetic and bioequivalence studies and therapeutic monitoring. The present work therefore aimed to develop and validate a high‐performance liquid chromatography coupled to tandem mass spectrometry (HPLC–MS/MS) method for the simultaneous quantification of these drugs in human plasma. The analyses were performed using an Agilent ...
Tópico(s): Pancreatic function and diabetes
2019 - Wiley | Biomedical Chromatography
Produção Nacional
Natalia Da Ponte Leguizamón, Elisandra Márcia Rodrigues, Michel Leandro de Campos, Andressa Vilas Boas Nogueira, Kennia Scapin Viola, Vanessa Karine Schneider, Daniela Morilha Neo-Justino, Mário Tanomaru‐Filho, Willian Fernando Zambuzzi, Flávio Henrique‐Silva, Andrea Soares‐Costa, Gisele Faria, Joni Augusto Cirelli,
Cystatins are natural inhibitors of cysteine peptidases. Recently, cystatins derived from plants, named phytocystatins, have been extensively studied. Among them, CsinCPI-2 proteins from Citrus sinensis were identified and recombinantly produced by our group. Thus, this study described the recombinant expression, purification, and inhibitory activity of this new phytocystatin against human cathepsins K and B and assessed the anti-inflammatory effect of CsinCPI-2 in vitro in mouse and in vivo in ...
Tópico(s): Phytase and its Applications
2019 - Elsevier BV | Cytokine
Produção Nacional
Revisado por pares
Michelle de Oliveira Pedrosa Rolim, Anderson Rodrigues de Almeida, Maíra Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Lucindo José Quintans‐Júnior, Jullyana de Souza Siqueira Quintans, Luana Heimfarth, Luciana Scotti, Luciana Scotti, Ryldene Marques Duarte da Cruz, Reinaldo Nóbrega de Almeida, Teresinha Gonçalves da Silva, Jonata Augusto de Oliveira, Michel Leandro de Campos, Pascal Marchand, Francisco Jaime Bezerra Mendonça,
The search for new drugs with anti-inflammatory properties remains a challenge for modern medicine. Among the various strategies for drug discovery, deriving new chemical entities from known bioactive natural and/or synthetic compounds remains a promising approach. Here, we designed and synthesized CVIB, a codrug developed by association of carvacrol (a phenolic monoterpene) with ibuprofen (a non-steroidal anti-inflammatory drug). In silico pharmacokinetic and physicochemical properties evaluation ...
Tópico(s): Pharmacological Effects of Natural Compounds
2019 - Elsevier BV | International Immunopharmacology
Produção Nacional
Revisado por pares
Cleverson Antônio Ferreira Martins, Michel Leandro de Campos, Ana Carolina Irioda, Dile Pontarolo Stremel, Angela C. L. B. Trindade, Roberto Pontarolo,
The ability of plant extracts and preparations to reduce inflammation has been proven by different means in experimental models. Since inflammation enhances the release of specific mediators, inhibition of their production can be used to investigate the anti-inflammatory effect of plants widely used in folk medicine for this purpose. The study was performed for leaves and flowers of Malva sylvestris, and leaves of Sida cordifolia and Pelargonium graveolens. These are three plant species known in ...
Tópico(s): Piperaceae Chemical and Biological Studies
2017 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Leandro Duarte Campos, Sulsiene Machado de Souza Gaia, Diogo Alves de Sordi, Felipe Mattos Tavares, Evandro Luiz Klein, Elem Cristina dos Santos Lopes,
Tópico(s): Geological and Geophysical Studies
2017 - Springer Science+Business Media | Natural Resources Research
Produção Nacional
Revisado por pares
Michel Leandro de Campos, Juliana de Moura Alonso, Evelin dos Santos Martins, Jonata Augusto de Oliveira, Carlos Alberto Hussni, Rosângela Gonçalves Peccinini,
Ceftriaxone is a cephalosporin antibiotic with a potent antimicrobial activity and excellent penetration in most body fluids such as pleural, peritoneal, spinal and brain. These facts contribute to the application of ceftriaxone in the treatment of bacterial peritonitis, an abdominal disorder in veterinary medicine, with potential risk of death. The determination of ceftriaxone levels in plasma and peritoneal fluid may be used to assess the pharmacokinetic profile at various instances of administration ...
Tópico(s): Pesticide Residue Analysis and Safety
2017 - Elsevier BV | Diagnostic Microbiology and Infectious Disease
Produção Nacional
Revisado por pares
Consuelo J. Perez, Alessandra Tata, Michel Leandro de Campos, Chun Peng, Demian R. Ifa,
Ambient mass spectrometry imaging has become an increasingly powerful technique for the direct analysis of biological tissues in the open environment with minimal sample preparation and fast analysis times. In this study, we introduce desorption electrospray ionization mass spectrometry imaging (DESI-MSI) as a novel, rapid, and sensitive approach to localize the accumulation of a mildly toxic ionic liquid (IL), AMMOENG 130 in zebrafish (Danio rerio). The work demonstrates that DESI-MSI has the potential ...
Tópico(s): Analytical Chemistry and Chromatography
2016 - American Chemical Society | Journal of the American Society for Mass Spectrometry
Produção Nacional
Revisado por pares
Marcelo Gomes Davanço, Michel Leandro de Campos, Talita Atanazio Rosa, Elias Carvalho Padilha, Alejandro Henao Alzate, Larissa Araújo Rolim, Pedró José Rolim Neto, Rosângela Gonçalves Peccinini,
Benznidazole (BNZ) is the first-line drug for the treatment of Chagas disease. The drug is available in the form of immediate-release tablets for 100-mg (adult) and 12.5-mg (pediatric) doses. The drug is administered two or three times daily for 60 days. The high frequency of daily administrations and the long period of treatment are factors that significantly contribute to the abandonment of therapy, affecting therapeutic success. Accordingly, this study aimed to evaluate the preclinical pharmacokinetics ...
Tópico(s): Parasites and Host Interactions
2016 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Produção Nacional
Revisado por pares
Leandro Cruz Campos, Marcos Vinícius Vieira Rocha, Denise Maria Cunha Willers, Denise Rossato Silva,
Introduction Smear-negative pulmonary TB (SNPT) represents 30–60% of all pulmonary TB cases. The mortality of these patients can reach 25% in populations with high prevalence of HIV infection, and 10–20% of TB transmission at the population level are attributable to SNPT cases. Methods We conducted a retrospective study to evaluate epidemiological, clinical, and radiological characteristics of patients with SNPT and to compare these with patients who were diagnosed as having smear-positive pulmonary ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2016 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Aline Pic‐Taylor, Luciana Gueiros da Motta, Juliana Alves de Morais, Willian Melo, Alana de Fátima Andrade Santos, Leandro Ambrósio Campos, Márcia Renata Mortari, Marcus Vinicius von Zuben, Eloísa Dutra Caldas,
Ayahuasca, a psychoactive beverage used by indigenous and religious groups, is generally prepared by the coction of Psychotria viridis and Banisteriopsis caapi plants containing N,N-dimethyltryptamine (DMT) and β-carboline alkaloids, respectively. To investigate the acute toxicity of ayahuasca, the infusion was administered by gavage to female Wistar rats at doses of 30X and 50X the dose taken during a religious ritual, and the animals observed for 14 days. Behavioural functions were investigated ...
Tópico(s): Neuroscience and Neuropharmacology Research
2015 - Elsevier BV | Behavioural Processes
Produção Nacional
Revisado por pares
Alessandra Tata, Consuelo J. Perez, Michel Leandro de Campos, Mark A. Bayfield, Marcos N. Eberlin, Demian R. Ifa,
Direct analysis of microbial cocultures grown on agar media by desorption electrospray ionization mass spectrometry (DESI-MS) is quite challenging. Due to the high gas pressure upon impact with the surface, the desorption mechanism does not allow direct imaging of soft or irregular surfaces. The divots in the agar, created by the high-pressure gas and spray, dramatically change the geometry of the system decreasing the intensity of the signal. In order to overcome this limitation, an imprinting step, ...
Tópico(s): Plant and animal studies
2015 - American Chemical Society | Analytical Chemistry