Produção Nacional
Revisado por pares
Leda Márcia Araújo Bento, Márcia M. Fagian, Anı́bal E. Vercesi, José Antônio Rocha Gontijo,
We have previously shown that chronic metabolic acidosis, induced in rats by NH(4)Cl feeding, leads to nephron hypertrophy and to a decreased water-salt reabsorption by the kidneys. Since mitochondria are the main source of metabolic energy that drives ion transport in kidney tubules, we examined energy-linked functions (respiration, electrochemical membrane potential and coupling between respiration and ADP phosphorylation) in mitochondria isolated from rat kidney and liver at 48 h after metabolic ...
Tópico(s): Ion Transport and Channel Regulation
2007 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Nelson Afonso Lutaif, Eduardo Melani Rocha, LícioA. Veloso, Leda Márcia Araújo Bento, José Antônio Rocha Gontijo,
Body temperature is closely regulated via the integration of a number of mechanisms, the study of which has been greatly assisted by the exploitation of comparative physiology. Previous studies have demonstrated that chronic renal failure patients have significantly lower body temperatures than healthy subjects when artifacts from circadian changes were taken into consideration. We hypothesize that the blunting of renal sensory neurons after kidney partial ablation may contribute to the lack of ...
Tópico(s): Hormonal Regulation and Hypertension
2008 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Elisabeth Neumann, Mariana Gontijo Ramos, Leandro M. Santos, A.C.P. Rodrigues, Eliane Vieira, Luís Afonso, Jacques R. Nicoli, Leda Quércia Vieira,
Lactobacillus delbrueckii UFV-H2b20 has been shown to increase clearance of bacteria injected into the blood of germ-free mice. Moreover, it induces the production of type 1 cytokines by human peripheral mononuclear cells. The objective of the present study was to investigate the production of inflammatory cytokines [interleukin-12 (IL-12 p40), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ)] triggered in vitro by live, heat-killed or lysozyme-treated L. delbrueckii UFV-H2b20 and in vivo by ...
Tópico(s): Cytomegalovirus and herpesvirus research
2009 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Leda Márcia Araújo Bento, José Barreto Campello Carvalheira, Leonardo Fantinato Menegon, Mário J. A. Saad, José Antônio Rocha Gontijo,
Background. There is a surprising lack of experimental data on the mechanisms of NH4Cl-induced chronic metabolic acidosis which causes kidney hypertrophy. The NH4Cl treatment results in an absolute increase in kidney mass. Despite findings to indicate a close interaction between NH4Cl-induced chronic metabolic acidosis and renal enlargement, the role of the stimulated serine kinase cascade, mediated by the stepwise activation of extracellular signal-regulated kinase (ERK) signalling, on kidney hypertrophy ...
Tópico(s): Nitric Oxide and Endothelin Effects
2005 - Oxford University Press | Nephrology Dialysis Transplantation
Produção Nacional
Revisado por pares
Lêda Maria da Costa Pinheiro Frota, Rosana Ferreira Sampaio, José Lucivan Miranda, Rita Maria Cavalcante Brasil, Ana Paula Bensemann Gontijo, Juliana Vaz de Melo Mambrini, Marina B. Brandão, Marisa Cotta Mancini,
Children with congenital Zika syndrome (CZS) maintain severe motor impairments at the end of the first year of life. Presence of certain symptoms and comorbidities increase these children's vulnerability.
Tópico(s): Neonatal and fetal brain pathology
2020 - Elsevier BV | Heliyon
Produção Nacional
Revisado por pares
G. Wilson Fernandes, Lucas Arantes‐Garcia, Milton Barbosa, Newton P. U. Barbosa, Eugênia Kelly Luciano Batista, Wallace Beiroz, Fernando M. Resende, Anna Abrahão, Emmanuel Duarte Almada, Elaine Vasconcelos Bezerra Alves, Natacha Jordânia da Silva Alves, Patrícia Angrisano, Montserrat Arista, Juan Arroyo, André Jardim Arruda, Thaíse de Oliveira Bahia, Laura Braga, Lílian Brito, Marcos Callisto, Dario C. Paiva, Marilia Pinheiro de Carvalho, Abel Augusto Conceição, Leda N. Costa, António Jorge do Rosário Cruz, Jéssica Cunha-Blum, John Dagevos, Braulio Ferreira Souza Dias, Victor Diniz Pinto, Rodolfo Dirzo, Daniel Quedes Domingos, Lívia Echternacht, Stephannie Fernandes, José Eugênio Côrtes Figueira, Cecília F. Fiorini, Ana María Giulietti, Augusto Gomes, Vanessa M. Gomes, Bernardo Machado Gontijo, Fernando Figueiredo Goulart, Tadeu J. Guerra, Patrícia A. Junqueira, Débora Lima-Santos, Julia Marques, João Augusto Alves Meira‐Neto, Deise Tatiane Bueno Miola, Leonor Patrícia Cerdeira Morellato, Daniel Negreiros, Elizabeth Neire, Ana Carolina de Oliveira Neves, Frederico S. Neves, Samuel Novais, Yumi Oki, E.G. De Oliveira, Rafael S. Oliveira, Marco Otávio Dias Pivari, Euripedes Junior Pontes, Bernardo Ranieri, Rodrigo Pinheiro Ribas, Aldicìr Scariot, Carlos Ernesto Gonçalves Reynaud Schaefer, Letícia Sena, Pedro Giovâni da Silva, Paulo Ricardo Baier Siqueira, Natalia Costa Soares, Britaldo Soares‐Filho, Ricardo Solar, Marcelo Tabarelli, Rogério Vasconcellos, Evaldo F. Vilela, Fernando A. O. Silveira,
Global sustainability rests on a myriad of benefits provided by natural ecosystems that support human livelihoods and well-being, from biodiversity persistence to climate regulation. The undeniable importance of conserving tropical forests has drawn most of the conservation spotlight towards it. However, open ecosystems such as the Brazilian Campo Rupestre (rupestrian grassland), have been historically overlooked despite their high diversity and key associated ecosystem services. We highlight major ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2020 - Elsevier BV | Perspectives in Ecology and Conservation
Produção Nacional
Revisado por pares
Camila Lopes Veronez, Agatha Ribeiro Mendes, Caroliny Souza Leite, Caio Perez Gomes, Anete Sevciovic Grumach, João Bosco Pesquero, Nathália Cagini, Eli Mansour, Jane da Silva, Pedro Giavina‐Bianchi, Ana Júlia Ribeiro Teixeira, Solange Oliveira Rodrigues Valle, Ekaterini Goudouris, Faradiba Sarquis Serpa, Therezinha Ribeiro Moyses, Fernanda Lugão Campinhos, Luís Felipe Ensina, Carolina Sánchez Aranda, Maria Cândida Rizzo, Régis A. Campos, Rozana Fátima Gonçalves, Fernanda Gontijo Minafra, Marli de Souza Bernardes, Herberto José Chong‐Neto, Nelson Augusto Rosário Filho, Carolina Guth, Eliana Toledo, Gabriela Andrade Coelho Dias, Miguel Alberto Piccirillo, Janáira Fernandes Severo Ferreira, Fernanda Marcelino, Pedro da Rocha Rolins Neto, Jackeline Franco, Gustavo Pafume de Sá, Laila Sabino Garro, Ana Carolina da Matta Ain, Helena Fleck Velasco, Ellaine Dóris Fernandes Carvalho, Maria Denise Fernandes Carvalho de Andrade, Cristiane Alves Boll, Natasha Rebouças Ferraroni, Ana Carolina Martins Pinto Swensson, Leandro Augusto Vilela Rabelo, Joanemile P. Figueiredo, Raphael Coelho Figueredo, Ronney Corrêa Mendes, Valéria Soraya Farias Sales, Luíz Leite, Ana Paula Beltrán Moschione Castro, Elke C. Ferreira Mascarenhas, Thaís Bomfim Teixeira, Camila Aparecida Campos Teixeira, Adriana Pereira de Lira Marques, Ludmilla Luzia Pires Amaral Resende, Leda das Neves Almeida Sandrin, Clarissa Soares Tavares,
Primary angioedema (PA) is a complex disorder, presenting multiple hereditary (hereditary angioedema) and acquired subtypes (acquired angioedema). Despite a very similar clinical presentation among subtypes, the differential diagnosis is limited by the difficulty to identify bradykinin-mediated PA and the lack of specific biomarkers.To report the clinical and genetic features of Brazilian patients with PA.Brazilian patients referred from 50 centers were diagnosed on the basis of clinical symptoms, ...
Tópico(s): Urticaria and Related Conditions
2020 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice