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Lew Baxter, John Huxley, Malcolm Brown, Barbara Hall, Toby Moore Agriculture Correspondent, Victoria Glendinning, Will Ellsworth-Jones, Abdul Shamji, Richard Brooks Communications Correspondent, Anne Spackman, Frank Barber, Chris Ryder, Dewey Gram, Rob Hughes, Kate Kellaway, P Turton, George Jones Political Correspondent, Chris Tighe, Christopher Reid, Patrick Bishop, David Hatton, Diana Wright Personal Finance Editor, Mark Lawson, Nick Pitt, John Huxley Industrial Editor, Jason Tomas, Cal McCrystal, Mark Hosenball, D H Lawrence, Henry Porter, Dalbert Hallenstein, Aldington, R. Buchanan-Dunlop, Fabian Acker, Patrick Stoddart, Mario Modiano, Iain Johnstone, Hugh Brogan, James McElroy, John Newell, Robert Hewison, Ivan Fallon, Dr Julian Lewis Director, Simon Grant, John Mortimer, Gilberto Gil, John Witherow, Nicholas Shrimpton, Maria Laura Avignolo, Haluk Sahin, Tim Glover, Sarah Helm, Gavin Green, Stephen Milligan Foreign Editor, David Cairns, Carol Price, Gavin Stamp, Geoff Whitten, Peter Ackroyd, Michael Jones, Yvonne Roberts, Des O'Sullivan, Byron Rogers, Philip Robinson, Anita Brookner, Frances Bissell, Bernard Cafferty, Tana de Zulueta, Roger Eglin, David Connett Crossmaglen, Elizabeth Bode, Sue Stewart, Dr Tuder Parfitt Lecturer, Paul Driver, Anne Jacobs Local Government Correspondent, Brian Jackman, John Hopkins, D M Thomas, Bryan Silcock, Simon Freeman, Roger Wilsher, David Brittain, Gareth Huw Davies, Julian Bright, James Wilson, Simon Frith, Diana Wright, William Peakin, Angela Wilkes, Tim Congdon, Stephen Jones, Tony Levene, Meriel McCooey, Martha Honey, Norman Lebrecht, Irene Woodman, Patrick Rowley, Dilys Powell, David Lipsey, Elizabeth Jane Howard, Russell Miller, Brough Scott, Deyan Sudjic, Caroline McGhie, Tony Osman, Rose Shepherd Editor, Stuart Alexander, Wilfred Thesiger, Kim Fletcher, Simon Winchester, John England, Maurice Chittenden, Amber Carol, Claire Green, Tim Blackstone, Sue Summers, Stephen Fay, Chris Nawrat, Amanda Craig, Mihir Bose, Simon Callow, Philip Beresford, Godfrey Smith, A Duggan, Neil Collins Editor, Gwynn Boyd Harte, Walter Eltis, Brian Glanville, George Rosle, Tim McGirk, Norman Tebbit, Patricia Mowbray, Rosemary Fox, Michael Green, Roy Isacowitz, Ian Williams, Peter Jenkins, Marina Vaizey, Chris Lightbown, Andrew Graham-Dixon, David Montgomery, George Jones, Nick Higham, Tony Hetherington, Julia Bright, Neil Collins, Donald Fields, Sue Summers Editor, Peter Roebuck, Peter Wilby Education Correspondent, Beverly Hayne, Nigel Horne, Jon Connell, Leslie Geddes-Brown, Boris Schapiro,

... Alfa Romeo Multiple Display Advertising Items Ski Freedom Abreu Multiple Display Advertising Items Aston Martin Volante Autosearch ...

1985 - Gale Group | Sunday Times HA GDA

Artigo Revisado por pares

Dirk J. de Jong, Karel J.M. Assmann, Ronney A. De Abreu, L.A.H. Monnens, F. van Liebergen, Henri B.P.M. Dijkman, F.T.M. Huysmans,

... Jong, Karel J.M. Assmann, Ronney A. De Abreu, Leo A.H. Monnens, Frans J.H.M. Van ... this author , Ronney A. De AbreuRonney A. De Abreu More articles by this author , Leo A.H. MonnensLeo A.H. Monnens More articles ... More articles by this author Ronney A. De Abreu More articles by this author Leo A.H. Monnens More articles by this author ...

Tópico(s): Cytomegalovirus and herpesvirus research

1996 - Lippincott Williams & Wilkins | The Journal of Urology

Revisão Revisado por pares

Annelies E. van Ede, Roland Laan, Henk J. Blom, Ronney A. De Abreu, Leo B. A. Van De Putte,

To provide an update of the current knowledge of the mechanism ofaction of low-dose methotrexate (MTX) in the treatment of patients with rheumatoid arthritis (RA), with an emphasis on the mechanisms involved in toxicity. We also considered strategies currently used to prevent or decrease toxicity of MTX. We reviewed the literature dealing with the subjects of MTX treatment ofRA, the mechanisms of action of low-dose MTX regarding efficacy and toxicity, and strategies used to prevent or decrease MTX ...

Tópico(s): Chronic Myeloid Leukemia Treatments

1998 - Elsevier BV | Seminars in Arthritis and Rheumatism

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Cláudia Schweiger, Denise Manica, Carolina Fischer Becker, Larissa Santos Perez Abreu, Michelle Manzini, Leo Sekine, Gabriel Kuhl,

Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications.To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities, complications and decannulation rates.Retrospective study concerning patients under 18 years of age undergoing tracheostomy in a tertiary health care center, from January 2006 to November 2015.123 children ...

Tópico(s): Head and Neck Surgical Oncology

2016 - Elsevier BV | Brazilian Journal of Otorhinolaryngology

Artigo Acesso aberto

P. J. S. M. Kerstens, Jan Stolk, Ronney A. De Abreu, Lambert H.J. Lambooy, Leo B. A. De Van Putte, Agnes A. M. T. Boerbooms,

Objective. Azathioprine (AZA) metabolism largely parallels the endogenous purine pathways. To date, thiopurine methyltransferase (TPMT) deficiency has been reported as a cause of AZA-related bone marrow toxicity in 1 patient with rheumatoid arthritis (RA). We therefore studied purine enzyme activities in 3 patients with RA who experienced AZA-related bone marrow toxicity. Methods. Lymphocyte activity of purine nucleoside phosphorylase and 5′-nucleotidase (5NT) and erythrocyte activity of TPMT, key enzymes ...

Tópico(s): Autoimmune and Inflammatory Disorders Research

1995 - Wiley | Arthritis & Rheumatism

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maurício Silva dos Santos, Adriana O. Gomes, Alice M. R. Bernardino, Marcos C. de Souza, Misbahul Ain Khan, Monique Araújo de Brito, Helena Carla Castro, Paula Alvarez Abreu, Carlos Rangel Rodrigues, Rosa M. M. de Léo, Leonor L. Leon, Marilene M. Canto‐Cavalheiro,

Chemotherapy for leishmaniasis, diseases caused by protozoa of the genus Leishmania, remains inefficient in several treatments. So there is a need to search for new drugs. In this work, we have synthesized 1-aryl-1H-pyrazole-4-carboximidamides derivatives and evaluated antileishmanial activities in vitro, as well as cytotoxic effects. Structure-activity relationship (SAR) studies were carried out with all the compounds of the series. Compound 2 showed an activity profile that can be improved through ...

Tópico(s): Synthesis and Characterization of Heterocyclic Compounds

2011 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society

Artigo

Marinella De Leo, Maryan Bruzual De Abreu, Agata Pawłowska, Pier Luigi Cioni, Alessandra Braca,

The qualitative and quantitative analysis of flavonoids from Opuntia ficus-indica flowers methanol extract from the Mediterranean area is described. On the basis of HPLC–PDA-ESI-MS/MS analysis seven compounds have been identified as kaempferol, quercetin, and isorhamnetin glycosylated derivatives. The total amount of flavonoids of O. ficus-indica flowers was 81.75 mg/1 g of fresh plant material, with isorhamnetin 3-O-robinobioside being the major component (52.22%). The plant flowers volatiles composition ...

Tópico(s): Plant Diversity and Evolution

2009 - Elsevier BV | Phytochemistry Letters

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Carmo Pereira Nunes, Cláudio Léo Gelape, Teresa Cristina Abreu Ferrari,

To describe the epidemiological, clinical, and laboratory profile of infective endocarditis (IE) at a Brazilian tertiary care center, and to identify the predictors of in-hospital mortality.Data from 62 patients who fulfilled the modified Duke's criteria for IE during a seven-year period were gathered prospectively. The Cox proportional hazards model was used to identify predictive factors for death.The mean age of patients was 45 years, and 39 patients (63%) were male. The median time from admission ...

Tópico(s): Bacterial Identification and Susceptibility Testing

2009 - Elsevier BV | International Journal of Infectious Diseases

Artigo Acesso aberto Revisado por pares

Konstantinos A. Papadakis, Leo Treyzon, María T. Abreu, Phillip Fleshner, Stephan R. Targan, Eric A. Vasiliauskas,

Summary Aim : To examine the outcome of infliximab intervention in refractory indeterminate colitis. Methods : Twenty patients with severe, medically refractory indeterminate colitis were treated with infliximab. All patients initially received infliximab, 5 mg/kg, intravenously and, in some patients, the dose was subsequently increased to 10 mg/kg. The number of infusions ranged from one to 16 per patient. Indeterminate colitis was defined as colitis that could not be classified with certainty as Crohn' ...

Tópico(s): Helicobacter pylori-related gastroenterology studies

2003 - Wiley | Alimentary Pharmacology & Therapeutics

Revisão Brasil Produção Nacional Revisado por pares

Maria Carmo Pereira Nunes, Milton Henriques Guimarães Júnior, Adriana C Diamantino, Cláudio Léo Gelape, Teresa Cristina Abreu Ferrari,

Abstract The heart may be affected directly or indirectly by a variety of protozoa and helminths. This involvement may manifest in different ways, but the syndromes resulting from impairment of the myocardium and pericardium are the most frequent. The myocardium may be invaded by parasites that trigger local inflammatory response with subsequent myocarditis or cardiomyopathy, as occurs in Chagas disease, African trypanosomiasis, toxoplasmosis, trichinellosis and infection with free-living amoebae. In amoebiasis ...

Tópico(s): Research on Leishmaniasis Studies

2017 - BMJ | Heart

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Carmo Pereira Nunes, Milton Henriques Guimarães Júnior, Pedro Henrique Oliveira Murta Pinto, Rodrigo Coelho, Thais Lins Souza Barros, Nicole de Paula Aarão Faleiro Maia, Dayane Amaral Madureira, Rodrigo Citton Padilha dos Reis, Paulo Henrique Nogueira Costa, Renato Bráulio, Cláudio Léo Gelape, Teresa Cristina Abreu Ferrari,

BackgroundThe early identification of patients at risk of complications of infective endocarditis (IE) using parameters obtained as part of routine practice is essential for guiding clinical decision-making. This study aimed to identify a parameter at hospital admission that predicts the outcome, adding value to other well-known factors of a poor prognosis in IE.MethodsTwo hundred and three patients with IE were included in this study. Clinical evaluation, echocardiography, blood cultures, and routine ...

Tópico(s): Antimicrobial Resistance in Staphylococcus

2018 - Elsevier BV | International Journal of Infectious Diseases

Artigo Revisado por pares

Williams Turpin, Osvaldo Espin‐Garcia, Larbi Bedrani, Karen Madsen, Jonathan B. Meddings, Juan A. Raygoza Garay, Mark S. Silverberg, Michelle I. Smith, Anne M. Griffiths, Paul Moayyedi, John K. Marshall, David R. Mack, Ernest G. Seidman, Mark J. Ropeleski, Brian G. Feagan, Kevan Jacobson, Dan Turner, Thomas D. Walters, Andrew D. Paterson, Maria Abreu, Paul L. Beck, Çharles N. Bernstein, Kenneth Croitoru, Leo Dieleman, Brian G. Feagan, Anne M. Griffiths, David Guttman, Kevan Jacobson, Gilaad G. Kaplan, Denis O. Krause, Karen Madsen, John K. Marshall, Paul Moayyedi, Mark J. Ropeleski, Ernest G. Seidman, Mark S. Silverberg, Scott B. Snapper, Andy Stadnyk, Hilary Steinhart, Michael G. Surette, Dan Turner, Tom Walters, Bruce A. Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee A. Denson, Colette Deslandres, Wael El‐Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David R. Mack, Jerry McGrath, Dennis G. Cvitkovitch, Anthony Otley, Remo Panancionne, Çharles N. Bernstein, Colette Deslandres, Desmond Leddin, Donald S. Daly, Fred Saibil, Guy Aumais, Hein Huynh, Herbert Brill, Hillary Steinhart, Iwona Wrobel, Jeff Critch, Jeff Hyams, Jennifer Jones, Jerry McGrath, Leo Dieleman, Maria Cino, Martha H. Dirks, Neal S. LeLeiko, Pierre Paré, Remo Panancionne, Mark S. Silverberg, Anne M. Griffiths, John K. Marshall, David R. Mack, Ernest G. Seidman, Mark J. Ropeleski, Brian G. Feagan, Kevan Jacobson, Thomas D. Walters, Wei Xu, Kenneth Croitoru,

Abstract Excessive intestinal permeability or intestinal barrier dysfunction as measured by various assays has been observed in various diseases. However, little is known about the factors contributing to altered gut permeability in these diseases. Our objective was to determine the genetic determinants of altered gut permeability as measured by the lactulose mannitol fractional excretion ratio (LacMan ratio) in 1075 healthy first-degree relatives of patients with Crohn’s disease (CD). In a targeted ...

Tópico(s): Digestive system and related health

2019 - Oxford University Press | Inflammatory Bowel Diseases

Artigo Acesso aberto Revisado por pares

Williams Turpin, Sun-Ho Lee, Juan A. Raygoza Garay, Karen Madsen, Jonathan B. Meddings, Larbi Bedrani, Namita Power, Osvaldo Espin‐Garcia, Wei Xu, Michelle I. Smith, Anne M. Griffiths, Paul Moayyedi, Dan Turner, Ernest G. Seidman, A. Hillary Steinhart, John K. Marshall, Kevan Jacobson, David Mack, Hien Q. Huynh, Çharles N. Bernstein, Andrew D. Paterson, Kenneth Croitoru, Maria Abreu, Paul L. Beck, Çharles N. Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Anne M. Griffiths, David S. Guttman, Kevan Jacobson, Gilaad G. Kaplan, Denis O. Krause, Karen Madsen, John K. Marshall, Paul Moayyedi, Mark J. Ropeleski, Ernest G. Seidman, Mark S. Silverberg, Scott B. Snapper, Andy Stadnyk, Hillary Steinhart, Michael G. Surette, Dan Turner, Thomas D. Walters, Bruce A. Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee A. Denson, Colette Deslandres, Wael El‐Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David Mack, Jerry McGrath, Anthony Otley, Remo Panancionne, Guy Aumais, Robert N. Baldassano, Çharles N. Bernstein, Maria Cino, Lee A. Denson, Colette Deslandres, Wael El‐Matary, Anne M. Griffiths, Charlotte Hedin, Hans Herfarth, Peter Higgins, Séamus Hussey, Hien Hyams, Kevan Jacobson, David J. Keljo, David Kevans, Charlie W. Lees, David Mack, John K. Marshall, Jerry McGrath, Sanjay K. Murthy, Anthony Otley, Remo Panaccione, Nimisha Parekh, Sophie Plamondon, Graham Radford-Smith, Mark J. Ropeleski, Joel R. Rosh, David T. Rubin, Michael Schultz, Ernest G. Seidman, Corey A. Siegel, Scott B. Snapper, Hillary Steinhart, Dan Turner,

Background & Aims Increased intestinal permeability has been associated with Crohn's disease (CD), but it is not clear whether it is a cause or result of the disease. We performed a prospective study to determine whether increased intestinal permeability is associated with future development of CD. Methods We assessed the intestinal permeability, measured by the urinary fractional excretion of lactulose-to-mannitol ratio (LMR) at recruitment in 1420 asymptomatic first-degree relatives (6–35 years old) of patients ...

Tópico(s): Drug Transport and Resistance Mechanisms

2020 - Elsevier BV | Gastroenterology

Artigo Acesso aberto Revisado por pares

Alexandra E. Livanos, Alexandra Dunn, J Fischer, Ryan C. Ungaro, Williams Turpin, Sun-Ho Lee, Shumin Rui, Diane M. Del Valle, Julia Jougon, Gustavo Martínez-Delgado, Mark S. Riddle, Joseph A. Murray, Renée M. Laird, Joana Torres, Manasi Agrawal, Jared Magee, Thierry Dervieux, Sacha Gnjatic, Dean Sheppard, Bruce E. Sands, Chad K. Porter, Kenneth Croitoru, Francesca Petralia, Maria Abreu, Paul L. Beck, Çharles N. Bernstein, Kenneth Croitoru, Leo Dieleman, Brian G. Feagan, Anne Griffiths, David Guttman, Kevan Jacobson, Gilaad G. Kaplan, Denis O. Krause, Karen Madsen, John K. Marshall, Paul Moayyedi, Mark J. Ropeleski, Ernest G. Seidman, Mark S. Silverberg, Scott B. Snapper, Andy Stadnyk, Hillary Steinhart, Michael G. Surette, Dan Turner, Tom Walters, Bruce A. Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee A. Denson, C Deslandres, Wael El‐Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David Mack, Jerry McGrath, Anthony Otley, Remo Panancionne, Jason Shapiro, Samir Shah, Neal S. LeLeiko, Jean‐Frédéric Colombel, Saurabh Mehandru,

Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 (anti-αvβ6) autoantibodies have been described in patients with UC. We tested for the presence of anti-αvβ6 antibodies in the preclinical phase of UC and studied their association with disease-related outcomes after diagnosis.Anti-αvβ6 autoantibodies were measured in 4 longitudinal serum samples collected from 82 subjects who later developed UC and 82 matched controls from a Department ...

Tópico(s): Autoimmune and Inflammatory Disorders

2023 - Elsevier BV | Gastroenterology

Artigo Revisado por pares

Williams Turpin, Mei Dong, Gila Sasson, Juan A. Raygoza Garay, Osvaldo Espin‐Garcia, Sun-Ho Lee, Anna Neustaeter, Michelle I. Smith, Haim Leibovitzh, David S. Guttman, Ashleigh Goethel, Anne M. Griffiths, Hien Q. Huynh, Levinus A. Dieleman, Remo Panaccione, A. Hillary Steinhart, Mark S. Silverberg, Guy Aumais, Kevan Jacobson, David R. Mack, Sanjay K. Murthy, John K. Marshall, Çharles N. Bernstein, Maria T. Abreu, Paul Moayyedi, Andrew D. Paterson, Wei Xu, Kenneth Croitoru, Maria Abreu, Paul L. Beck, Çharles N. Bernstein, Kenneth Croitoru, Leo Dieleman, Brian Feagan, Anne M. Griffiths, David S. Guttman, Kevan Jacobson, Gilaad G. Kaplan, Denis O. Krause, Karen Madsen, John K. Marshall, Paul Moayyedi, Mark J. Ropeleski, Ernest G. Seidman, Mark S. Silverberg, Scott B. Snapper, Andy Stadnyk, Hillary Steinhart, Michael G. Surette, Dan Turner, T D Walters, Bruce A. Vallance, Guy Aumais, Alain Bitton, Maria Cino, Jeff Critch, Lee A. Denson, Colette Deslandres, Wael El‐Matary, Hans Herfarth, Peter Higgins, Hien Q. Huynh, Jeff Hyams, David R. Mack, Jerry McGrath, Anthony Otley, Remo Panancionne, Guy Aumais, Robert N. Baldassano, Çharles N. Bernstein, Lee A. Denson, Colette Deslandres, Wael El‐Matary, Anne M. Griffiths, Charlotte Hedin, Hans Herfarth, Peter Higgins, Séamus Hussey, Hien Hyams, Kevan Jacobson, David J. Keljo, David Kevans, Charlie W. Lees, David R. Mack, John K. Marshall, Jerry McGrath, Sanjay K. Murthy, Anthony Otley, Remo Panaccione, Nimisha Parekh, Sophie Plamondon, Graham Radford-Smith, Mark J. Ropeleski, Joel R. Rosh, David T. Rubin, Michael Schultz, Ernest G. Seidman, Corey A. Siegel, Scott B. Snapper, Hillary Steinhart, Dan Turner,

Background & Aims Case-control studies have shown that patients with Crohn's disease (CD) have a microbial composition different from healthy individuals. Although the causes of CD are unknown, epidemiologic studies suggest that diet is an important contributor to CD risk, potentially via modulation of bacterial composition and gut inflammation. We hypothesized that long-term dietary clusters (DCs) are associated with gut microbiome compositions and gut inflammation. Our objectives were to identify dietary patterns ...

Tópico(s): Nutritional Studies and Diet

2022 - Elsevier BV | Gastroenterology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Leandro dos Santos Machado, Felipe Faccini dos Santos, Cristina Kimie Togashi, Dayse Lima da Costa Abreu, Jorge Couto Pimentel, Luiz Sesti, Virgínia Léo de Almeida Pereira, Elmiro Rosendo do Nascimento,

Mycoplasma gallisepticum causes coughing, ocular and nasal discharge, reduction in feed intake, lower and uneven growth, decline in egg production and quality, and increase in mortality. Among the attenuated vaccination strains, MGF can reduce clinical signs and lesions in layer hens, stimulate immune responses of cellular and humoral basis, act as an instrument of competitive exclusion in relation to field strains, and reduce the use of antimicrobials. This study aimed to investigate the effects ...

Tópico(s): Herpesvirus Infections and Treatments

2016 - Elsevier BV | Poultry Science

Artigo Acesso aberto

Jan Stolk, A M Boerbooms, Ronney A. De Abreu, Diana G. M. de Koning, H. J. Van Beusekom, W Müller, Leo B. A. Van De Putte,

Objective To investigate thiopurine enzyme activities for their possible value in predicting the development of azathioprine (AZA)-related toxicity in patients with rheumatoid arthritis (RA). Methods Patients with longstanding RA (n = 33) were enrolled in a study of treatment with AZA. Before the initiation of AZA treatment and at months 1 and 6 of treatment, we measured activities of the purine key enzymes hypoxanthine guanine phosphoribosyltransferase, 5′-nucleotidase, purine nucleoside phosphorylase, ...

Tópico(s): Renal Transplantation Outcomes and Treatments

1998 - Wiley | Arthritis & Rheumatism

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

L. Nabuco de Abreu, María A. Oquendo, Hanga Galfavy, Ainsley K. Burke, Michael F. Grunebaum, Leo Sher, Gregory M. Sullivan, M. Elizabeth Sublette, J. John Mann, Beny Lafer,

Abstract Background: Comorbid anxiety disorders have been considered a risk factor for suicidal behavior in patients with mood disorders, although results are controversial. The aim of this two-year prospective study was to determine if lifetime and current comorbid anxiety disorders at baseline were risk factors for suicide attempts during the two-year follow-up. Methods: We evaluated 667 patients with mood disorders (504 with major depression and 167 with bipolar disorder) divided in two groups: ...

Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

2017 - Cambridge University Press | European Psychiatry

Artigo

Antonia Sambola, Jordi Lozano-Torres, Eric Boersma, Carmen Olmos, Julien Ternacle, Francisco Calvo, Christophe Tribouilloy, Vlatka Rešković Lukšić, Jadranka Šeparović Hanževački, Seung Woo Park, Sebastiaan C.A.M. Bekkers, Kwan‐Leung Chan, Abdallah Almaghraby, Bernard Iung, Patrizio Lancellotti, Gilbert Habib, Roberto Ferrari, Ángel Barajas, J. J. Bax, Carina Blomström‐Lundqvist, S. Gielen, Aldo P. Maggioni, Patrizio Lancellotti, N Maniadakis, Fausto J. Pinto, Frank Ruschitzka, L. Tavazzi, PE Vardas, F Weidinger, Uwe Zeymer, Alec Vahanian, Andrzej Budaj, Nikolaos Dagres, Nicolas Danchin, Victoria Delgado, Jonathan Emberson, Örjan Friberg, Chris P Gale, Gr. Heyndrickx, Bernard Iung, Sherman A. James, A P Kappetein, Aldo P. Maggioni, N Maniadakis, Kristóf Nagy, G Parati, A-S Petronio, Mikko Pietilä, E Prescott, Frank Ruschitzka, Frans Van de Werf, F Weidinger, Uwe Zeymer, Gilbert Habib, Patrizio Lancellotti, Bernard Cosyns, Erwan Donal, Paola Anna Erba, Gilbert Habib, Bernard Iung, Aldo P. Maggioni, Bogdan A. Popescu, Bernard Prendergast, Pilar Tornos, Nora Nabila Ali Tatar-Chentir, Mouaz H. Al–Mallah, Meriam Åström Aneq, George Athanassopoulos, Luigi P. Badano, S. Benyoussef, Erick Calderón-Aranda, Nuno Cardim, Kwan‐Leung Chan, Bernard Cosyns, Ines Cruz, Thor Edvardsen, Georg Goliasch, Gilbert Habib, Andreas Hagendorff, Krasimira Hristová, Bernard Iung, Otto Kamp, Duk‐Hyun Kang, William Kong, С.Т. Мацкеплишвили, Marwa Sayed Meshaal, M Mirocevic, Aleksandar Nešković, Michal Pazderník, Edyta Płońska‐Gościniak, Bogdan A. Popescu, Bernard Prendergast, Maha Raissouni, Ricardo Ronderos, Leyla Elif Sade, Anita Sadeghpour, Antonia Sambola, Shantanu P. Sengupta, Jadranka Šeparović Hanževački, Masaaki Takeuchi, Edwin S. Tucay, Ana Clara Tude Rodrigues, Albert Varga, Jolanta Justina Vaškelytė, Kentaro Yamagata, Kyriakos Yiangou, Hosam Zaky, Ricardo Ronderos, Gustavo Avegliano, P. Fernandez Oses, Eduardo Filipini, Isabel Granada, Ana Iribarren, M Mahia, Francisco Nacinovich, S Ressi, Ramón De la Cruz Obregón, M Bangher, J Dho, Luis Cartasegna, M. Plastino, V Novas, C Shigel, Graciela Reyes, Lurdes Santos, Natalio Gastaldello, M Granillo Fernandez, M Potito, Gisela Streitenberger, P Velazco, José Casabé, Claudia Cortés, Eduardo Guevara, Fabián Salmo, M Seijo, F Weidinger, Maria Heger, Renee L. Brooks, Claudia Stöllberger, Carolyn Y. Ho, Leonard Perschy, L Puskas, Georg Goliasch, Christian Binder, Raphaël Rosenhek, M Schneider, MP Winter, E Hoffer, M Melissopoulou, E Lecoq, D. Legrand, Sandrine Jacquet, M Massoz, Patrizio Lancellotti, Luc Piérard, Raluca Dulgheru, Stella Marchetta, Céline D'Emal, Cécile Oury, Bernard Cosyns, S Droogmans, D. Kerkhove, Andreea Motoc, D. Plein, Bram Roosens, L Soens, Caroline Weytjens, I Lemoine, Inez Rodrigus, Bernard P. Paelinck, Bram J. Amsel, Philippe Unger, Déborah Konopnicki, C. Beauloye, Agnès Pasquet, S Pierard, David Vancraeynest, Jean‐Louis Vanoverschelde, F Sinnaeve, José Lázaro Andrade, Ana Clara Tude Rodrigues, Kamila Fernanda Staszko, R Dos Santos Monteiro, Marcelo Haertel Miglioranza, D L Shuha, M Alcantara, V Cravo, L Fazzio, Ana Félix, M Iso, C Musa, Ana Paula dos Reis Velloso Siciliano, Fábio Villaça Guimarães Filho, Juarez R. Braga, Ana Clara Tude Rodrigues, R Silva, F Vilela, Daniela Laranja Gomes Rodrigues, L Silva, Samira Saady Morhy, Cláudio Henrique Fischer, R Silva, Marcelo Luiz Campos Vieira, T. Afonso, J. Abreu, Sandra Nívea dos Reis Saraiva Falcão, Valdir Ambrósio Moisés, Agostinho Pinto Gouvêa, G João, Francesco M. Mancuso, Carina Silva, Ana Carolina Mello Fontoura de Souza, Cely Saad Abboud, Rodrigo Bellio de Mattos Barretto, A Ramos, Renato Tambellini Arnoni, Jorge Eduardo Assef, Dorival Júlio Della Togna, David Le Bihan, L. Miglioli, A P Romero Oliveira, Roberto Tadeu Magro Kroll, Daniel Cortez, Cláudio Léo Gelape, Mara Nunes, Teresa Cristina Abreu Ferrari, KL Chan, Kevin A. Hay, V. Le, Mathieu Page, Frédéric Poulin, Claude Sauvé, Karim Serri, Chantal Mercure, J Beaudoin, Philippe Pîbarot, Igal A. Sebag, Lawrence Rudski, G Ricafort, Bruno Baršić, Vladimir Krajinović, Martina Vargović, J Separovic-Hanzevacki, Daniel Lovrić, V Reskovic-Luksic, Josip Vincelj, Sandra Jakšić Jurinjak, V Yiannikourides, Marios Ioannides, Chara Kyriakou, C Pofaides, V Masoura, K Yiangou, Jiří Pudich, Aleš Linhart, Michal Širanec, J Marek, K Blechova, Mirt Kamenik, Michal Pazderník, Radek Pelouch, Zdeněk Coufal, M Mikulica, Martin Gřiva, Eva Jančová, M. Mikulcova, Miloš Táborský, Jan Přeček, Markéta Ječmenová, J. Latal, J Widimský, T. Butta, S Machacek, R. Vancata, Jindřich Špinar, Mária Holická, F Pow Chon Long, N Anzules, Arturo Carpio, G Largacha, Ernesto Peñaherrera, Davide Moreira, E Mahfouz, E Elsafty, Ahmed M. Soliman, Yazan Zayed, J Aboulenein, M Abdel-Hay, Abdallah Almaghraby, Mahmoud Abdelnaby, Mustafa I. Ahmed, Basma Hammad, Yehia Saleh, Hatice S. Zahran, O Elgebaly, Aly M A Saad,

Even though vegetation size in infective endocarditis (IE) has been associated with embolic events (EEs) and mortality risk, it is unclear whether vegetation size associated with these potential outcomes is different in left-sided IE (LSIE). This study aimed to seek assessing the vegetation cut-off size as predictor of EE or 30-day mortality for LSIE and to determine risk predictors of these outcomes.The European Society of Cardiology EURObservational Research Programme European Infective Endocarditis ...

Oxford University Press

Artigo Brasil Produção Nacional Revisado por pares

Gustavo Roncoli Reigado, Patrícia P. Adriani, Jeniffer Farias dos Santos, Bruna Letícia Freitas, Myrian Thiago Pruschinski Fernandes, Felipe S. Chambergo, Patrícia Léo, Viviane Abreu Nunes,

Abstract Trichoderma reesei superoxide dismutase (TrSOD) is a well‐characterized enzyme being stable between 30 and 90°C for 1 h with activity at pH between 2.6 and 9.0. This work aimed to clone, express, purify, and evaluate the protective effect antioxidant of this enzyme on skin cells when fused to transactivator of transcription (TAT) protein transduction domain of HIV‐1 and abalone (Ab) peptides to allow cell penetration. TrSOD, TAT‐TrSOD‐Yfp (fused to yellow fluorescent protein), and Ab‐TrSOD ...

Tópico(s): Invertebrate Immune Response Mechanisms

2022 - Wiley | Biotechnology and Applied Biochemistry

Artigo Brasil Produção Nacional Revisado por pares

Pedro Panzenhagen, Waldemir Silva de Aguiar, Beatriz da Silva Frasão, Virgínia Léo de Almeida Pereira, Dayse Lima da Costa Abreu, Dália dos Prazeres Rodrigues, Elmiro Rosendo do Nascimento, Maria Helena Cosendey de Aquino,

To investigate the prevalence of Campylobacter and Salmonella in poultry carcasses in state of Rio de Janeiro, Brazil, 60 samples from 6 slaughterhouses were collected over a period of 6 months. A total of 82 Campylobacter isolates were obtained from twenty seven (45%) positive chicken carcasses, including 44 isolates (53.66%) of Campylobacter jejuni and 38 (46.34%) of Campylobacter coli. The identification of all strains was confirmed by PCR. Salmonella was isolated from 4 (6.67%) carcasses by conventional ...

Tópico(s): Food Safety and Hygiene

2015 - Elsevier BV | Food Control

Artigo Revisado por pares

Leo Heunks, Herwin A. Machiels, Ronney A. De Abreu, Xiao Ping Zhu, Erik H.F.M. van der Heijden, P.N.R. Dekhuijzen,

Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about the role of free radicals in contractility of the rat diaphragm during hypoxia. We hypothesized that antioxidants improve contractility of the hypoxic rat diaphragm and that xanthine oxidase (XO) is an important source of free radicals in the hypoxic diaphragm. The effects of N-acetylcysteine (NAC; 18 mM), Tiron (10 mM), and the XO inhibitor allopurinol (250 μM) were studied on isometric and isotonic force ...

Tópico(s): High Altitude and Hypoxia

2001 - American Physical Society | AJP Lung Cellular and Molecular Physiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Ary Serpa Neto, Rodrigo Octávio Deliberato, Alistair E. W. Johnson, Lieuwe D. J. Bos, Pedro Amorim, Silvio Moreto Pereira, Denise Carnieli Cazati, Ricardo Luiz Cordioli, Thiago Domingos Corrêa, Tom Pollard, Guilherme Schettino, Karina Tavares Timenetsky, Leo Anthony Celi, Paolo Pelosi, Marcelo Gama de Abreu, Marcus J. Schultz,

Mechanical power (MP) may unify variables known to be related to development of ventilator-induced lung injury. The aim of this study is to examine the association between MP and mortality in critically ill patients receiving invasive ventilation for at least 48 h. This is an analysis of data stored in the databases of the MIMIC–III and eICU. Critically ill patients receiving invasive ventilation for at least 48 h were included. The exposure of interest was MP. The primary outcome was in-hospital ...

Tópico(s): Sepsis Diagnosis and Treatment

2018 - Springer Science+Business Media | Intensive Care Medicine

Artigo Acesso aberto Revisado por pares

Anna‐Friederike Marx, Sandra M. Kallert, Tobias M. Brunner, José A. Villegas, Florian Geier, Jonas Fixemer, Tiago Abreu-Mota, Peter Reuther, Weldy V. Bonilla, Jelizaveta Fadejeva, Mario Kreutzfeldt, Ingrid Wagner, Patricia Aparicio‐Domingo, Leo Scarpellino, Mélanie Charmoy, Daniel T. Utzschneider, Claudia Hagedorn, Min Lu, Karen Cornille, Karsten Stauffer, Florian Kreppel, Doron Merkler, Dietmar Zehn, Werner Held, Sanjiv A. Luther, Max Löhning, Daniel D. Pinschewer,

T cell factor 1 (Tcf-1) expressing CD8+ T cells exhibit stem-like self-renewing capacity, rendering them key for immune defense against chronic viral infection and cancer. Yet, the signals that promote the formation and maintenance of these stem-like CD8+ T cells (CD8+SL) remain poorly defined.Studying CD8+ T cell differentiation in mice with chronic viral infection, we identified the alarmin interleukin-33 (IL-33) as pivotal for the expansion and stem-like functioning of CD8+SL as well as for virus ...

Tópico(s): T-cell and B-cell Immunology

2023 - Cell Press | Immunity

Artigo Revisado por pares

Alvin C. Goh, Inderbir S. Gill, Dennis J. Lee, Andre Luis Abreu, Adrian Fairey, Scott Leslie, André Berger, Siamak Daneshmand, René Sotelo, Karanvir Gill, Hui Xie, Leo Y. Chu, Monish Aron, Mihir Desai,

Robotic radical cystectomy (RC) for cancer is beginning to gain wider acceptance. Yet, the concomitant urinary diversion is typically performed extracorporeally at most centers, primarily because intracorporeal diversion is perceived as technically complex and arduous. Previous reports on robotic, intracorporeal, orthotopic neobladder may not have fully replicated established open principles of reservoir configuration, leading to concerns about long-term functional outcomes.To illustrate step-by- ...

Tópico(s): Urological Disorders and Treatments

2012 - Elsevier BV | European Urology

Artigo

Gilbert Habib, Paola Anna Erba, Bernard Iung, Erwan Donal, Bernard Cosyns, Cécile Laroche, Bogdan A. Popescu, Bernard Prendergast, Pilar Tornos, Anita Sadeghpour, Léopold Oliver, Jolanta-Justina Vaškelytė, Rouguiatou Sow, Olivier Axler, Aldo P. Maggioni, Patrizio Lancellotti, Chris P Gale, B. Beleslin, Andrzej Budaj, Ovidiu Chioncel, Nikolaos Dagres, Nicolas Danchin, Jonathan Emberson, David Erlinge, Michael Glikson, Adam Gray, Meral Kayıkçıoğlu, Aldo P. Maggioni, V K Nagy, А. О. Недошивин, A-S Petronio, Jolien W. Roos‐Hesselink, Lars Wallentin, Uwe Zeymer, Gilbert Habib, Patrizio Lancellotti, Bernard Cosyns, Erwan Donal, Paola Anna Erba, Bernard Iung, Aldo P. Maggioni, Bogdan A. Popescu, Bernard Prendergast, P. Tornos, Maryna Andarala, C Berle, A Brunel-Lebecq, E Fiorucci, C Laroche, V. Missiamenou, Clare Taylor, Nora Nabila Ali Tatar-Chentir, Mouaz H. Al–Mallah, Meriam Åström Aneq, George Athanassopoulos, Luigi P. Badano, S. Benyoussef, Erick Calderón-Aranda, Nuno Cardim, KL Chan, Bernard Cosyns, Isabel Cruz, Thor Edvardsen, Georg Goliasch, Gilbert Habib, Andreas Hagendorff, Krasimira Hristová, Bernard Iung, Otto Kamp, D-H Kang, William Kong, С.Т. Мацкеплишвили, Marwa Sayed Meshaal, M Mirocevic, Aleksandar Nešković, Michal Pazderník, Edyta Płońska‐Gościniak, Bogdan A. Popescu, Bernard Prendergast, Maha Raissouni, Ricardo Ronderos, Leyla Elif Sade, Anita Sadeghpour, Antonia Sambola, Shantanu P. Sengupta, J Separovic-Hanzevacki, Masami Takeuchi, Edwin S. Tucay, Ana Clara Tude Rodrigues, Andréa Varga, J. Vaskelyte, Kazufumi Yamagata, K Yiangou, H. Zaky, Isabel Granada, M Mahia, S Ressi, Francisco Nacinovich, Ana Iribarren, P. Fernandez Oses, Gustavo Avegliano, Eduardo Filipini, Ramón De la Cruz Obregón, M Bangher, J Dho, Luis Cartasegna, M. Plastino, V Novas, C Shigel, Graciela Reyes, Lurdes Santos, Natalio Gastaldello, M Granillo Fernandez, M Potito, Gisela Streitenberger, P Velazco, José Casabé, Claudia Cortés, Eduardo Guevara, Fabián Salmo, M Seijo, F Weidinger, Maria Heger, Renee L. Brooks, Claudia Stöllberger, Carolyn Y. Ho, Leonard Perschy, L Puskas, Christian Binder, Raphaël Rosenhek, M Schneider, MP Winter, E Hoffer, M Melissopoulou, E Lecoq, D. Legrand, Sandrine Jacquet, M Massoz, Luc Piérard, Stella Marchetta, Raluca Dulgheru, C D ́ Emal, Cécile Oury, Steven Droogmans, D. Kerkhove, D. Plein, L Soens, Caroline Weytjens, Andreea Motoc, Bram Roosens, I Lemoine, Inez Rodrigus, Bernard P. Paelinck, Bram J. Amsel, Philippe Unger, Déborah Konopnicki, C. Beauloye, Agnès Pasquet, Jean‐Louis Vanoverschelde, S Pierard, David Vancraeynest, F Sinnaeve, José Lázaro Andrade, Kamila Fernanda Staszko, R Dos Santos Monteiro, Marcelo Haertel Miglioranza, D. L. Shuha, M Alcantara, V Cravo, L Fazzio, Ana Félix, M Iso, C Musa, Ana Paula dos Reis Velloso Siciliano, Fábio Villaça Guimarães Filho, Ana Clara Tude Rodrigues, F Vilela, Juarez R. Braga, R Silva, Daniela Laranja Gomes Rodrigues, L Silva, Samira Saady Morhy, Cláudio Henrique Fischer, R Silva, Marcelo Luiz Campos Vieira, T. Afonso, J. Abreu, Sandra Nívea dos Reis Saraiva Falcão, Valdir Ambrósio Moisés, Agostinho Pinto Gouvêa, Frederico Mancuso, Ana Carolina Mello Fontoura de Souza, C Y Silva, G João, Cely Saad Abboud, Rodrigo Bellio de Mattos Barretto, A Ramos, Renato Tambellini Arnoni, Jorge Eduardo Assef, Dorival Júlio Della Togna, David Le Bihan, L. Miglioli, A P Romero Oliveira, Roberto Tadeu Magro Kroll, Daniel Cortez, Cláudio Léo Gelape, M d C Peirira Nunes, Teresa Cristina Abreu Ferrari, Kevin A. Hay, V. Le, Mathieu Page, Frédéric Poulin, Claude Sauvé, Karim Serri, Chantal Mercure, J Beaudoin, Philippe Pîbarot, Igal A. Sebag, Lawrence Rudski, G Ricafort, Bruno Baršić, Vladimir Krajinović, Martina Vargović, Daniel Lovrić, V Reskovic-Luksic, Josip Vincelj, Sandra Jakšić Jurinjak, V Yiannikourides, Marios Ioannides, C Pofaides, V Masoura, Jiří Pudich, Aleš Linhart, Michal Širanec, J Marek, K Blechova, Mirt Kamenik, Radek Pelouch, Zdeněk Coufal, M Mikulica, Martin Gřiva, Eva Jančová, M. Mikulcova, Miloš Táborský, Jan Přeček, Markéta Ječmenová, J. Latal, J Widimský, T. Butta, S Machacek, R. Vancata, Jindřich Špinar, Mária Holická, F Pow Chon Long, N Anzules, Arturo Carpio, G Largacha, Ernesto Peñaherrera, Davide Moreira, E Mahfouz, E Elsafty, Amel M. Soliman, Yazan Zayed, J Aboulenein, M Abdel-Hay, Abdallah Almaghraby, Mahmoud Abdelnaby, Mustafa I. Ahmed, Basma Hammad, Yehia Saleh, Hatice S. Zahran, O Elgebaly, Aly M A Saad, Mohammed Ali, A Zeid, Reham El Sharkawy, A Al Kholy, Ramy Doss, Dina Osama, Hussien Rizk, A Elmogy, M Mishriky, Patrick Assayag, Safwane El Hatimi, S. Hubert, J-P Casalta, Frédérique Gouriet, Florent Arregle, Serge Cammilleri, L. Tessonnier, Alberto Ribéri, Élisabeth Botelho-Nevers, Amandine Gagneux‐Brunon, Romain Pierrard, C. Tulane, Saveria Campisi,

The EURO-ENDO registry aimed to study the management and outcomes of patients with infective endocarditis (IE).Prospective cohort of 3116 adult patients (2470 from Europe, 646 from non-ESC countries), admitted to 156 hospitals in 40 countries between January 2016 and March 2018 with a diagnosis of IE based on ESC 2015 diagnostic criteria. Clinical, biological, microbiological, and imaging [echocardiography, computed tomography (CT) scan, 18F-fluorodeoxyglucose positron emission tomography/computed tomography ( ...

Oxford University Press

Artigo

Gilbert Habib, Patrizio Lancellotti, P A Erba, Anita Sadeghpour, Marwa Sayed Meshaal, Antonia Sambola, Shumaila Furnaz, Rodolfo Citro, Julien Ternacle, Erwan Donal, Bernard Cosyns, Bogdan A. Popescu, Bernard Iung, Bernard Prendergast, Cécile Laroche, Pilar Tornos, Michal Pazderník, Aldo P. Maggioni, Chris P Gale, Nora Nabila Ali Tatar-Chentir, Mouaz H. Al–Mallah, Meriam Åström Aneq, George Athanassopoulos, Luigi P. Badano, S. Benyoussef, Erick Calderón-Aranda, Nuno Cardim, KL Chan, Bernard Cosyns, Isabel Cruz, Thor Edvardsen, Georg Goliasch, Gilbert Habib, Andreas Hagendorff, Krasimira Hristová, Bernard Iung, Otto Kamp, D-H Kang, William Kong, С.Т. Мацкеплишвили, Marwa Sayed Meshaal, M Mirocevic, Aleksandar Nešković, Michal Pazderník, Edyta Płońska‐Gościniak, Bogdan A. Popescu, Bernard Prendergast, Maha Raissouni, Ricardo Ronderos, Leyla Elif Sade, Anita Sadeghpour, Antonia Sambola, Shantanu P. Sengupta, J Separovic-Hanzevacki, Masami Takeuchi, Edwin S. Tucay, Ana Clara Tude Rodrigues, Andréa Varga, J. Vaskelyte, Kazufumi Yamagata, K Yiangou, H. Zaky, Isabel Granada, M Mahia, S Ressi, Francisco Nacinovich, Ana Iribarren, P. Fernandez Oses, Gustavo Avegliano, Eduardo Filipini, Ramón De la Cruz Obregón, M Bangher, J Dho, L Cartasegna, M. Plastino, V Novas, C Shigel, Graciela Reyes, Lurdes Santos, Natalio Gastaldello, M Granillo Fernandez, M Potito, Gisela Streitenberger, P Velazco, José Casabé, Claudia Cortés, Eduardo Guevara, Fabián Salmo, M Seijo, F Weidinger, Maria Heger, Renee L. Brooks, Claudia Stöllberger, Carolyn Y. Ho, Leonard Perschy, L Puskas, Christian Binder, Raphaël Rosenhek, M Schneider, MP Winter, E Hoffer, M Melissopoulou, E Lecoq, D. Legrand, Sandrine Jacquet, M Massoz, Luc Piérard, Stella Marchetta, Raluca Dulgheru, C. D ́Emal, Cécile Oury, Steven Droogmans, D. Kerkhove, D. Plein, L Soens, Caroline Weytjens, Andreea Motoc, Bram Roosens, I Lemoine, Inez Rodrigus, Bernard P. Paelinck, Bram J. Amsel, Philippe Unger, Déborah Konopnicki, C. Beauloye, Agnès Pasquet, Jean‐Louis Vanoverschelde, S Pierard, David Vancraeynest, F Sinnaeve, José Lázaro Andrade, Kamila Fernanda Staszko, R Dos Santos Monteiro, Marcelo Haertel Miglioranza, D. L. Shuha, M Alcantara, V Cravo, L Fazzio, Ana Félix, M Iso, C Musa, Ana Paula dos Reis Velloso Siciliano, Fábio Villaça Guimarães Filho, Ana Clara Tude Rodrigues, F Vilela, Juarez R. Braga, R Silva, Daniela Laranja Gomes Rodrigues, L Silva, Samira Saady Morhy, Cláudio Henrique Fischer, R Silva, Marcelo Luiz Campos Vieira, T. Afonso, J. Abreu, Sandra Nívea dos Reis Saraiva Falcão, Valdir Ambrósio Moisés, Agostinho Pinto Gouvêa, Frederico Mancuso, Ana Carolina Mello Fontoura de Souza, C Y Silva, G João, Cely Saad Abboud, Rodrigo Bellio de Mattos Barretto, A Ramos, Renato Tambellini Arnoni, Jorge Eduardo Assef, Dorival Júlio Della Togna, David Le Bihan, L. Miglioli, A P Romero Oliveira, Roberto Tadeu Magro Kroll, Daniel Cortez, Cláudio Léo Gelape, M d C Peirira Nunes, Teresa Cristina Abreu Ferrari, Kevin A. Hay, V. Le, Mathieu Page, Frédéric Poulin, Claude Sauvé, Karim Serri, Chantal Mercure, J Beaudoin, Philippe Pîbarot, Igal A. Sebag, Lawrence Rudski, G Ricafort, Bruno Baršić, Vladimir Krajinović, Martina Vargović, Daniel Lovrić, V Reskovic-Luksic, Josip Vincelj, Sandra Jakšić Jurinjak, V Yiannikourides, Marios Ioannides, C Pofaides, V Masoura, Jiří Pudich, Aleš Linhart, Michal Širanec, J Marek, K Blechova, Mirt Kamenik, Radek Pelouch, Zdeněk Coufal, M Mikulica, Martin Gřiva, Eva Jančová, M. Mikulcova, Miloš Táborský, Jan Přeček, Markéta Ječmenová, J. Latal, J Widimský, T. Butta, S Machacek, R. Vancata, Jindřich Špinar, Mária Holická, F Pow Chon Long, N Anzules, Arturo Carpio, G Largacha, Ernesto Peñaherrera, Davide Moreira, E Mahfouz, E Elsafty, Amel M. Soliman, Yazan Zayed, J Aboulenein, M Abdel-Hay, Abdallah Almaghraby, Mahmoud Abdelnaby, Mustafa I. Ahmed, Basma Hammad, Yehia Saleh, Hatice S. Zahran, O Elgebaly, Aly M A Saad, Mohammed Ali, A Zeid, Reham El Sharkawy, A Al Kholy, Ramy Doss, Dina Osama, Hussien Rizk, A Elmogy, M Mishriky, Patrick Assayag, Safwane El Hatimi, S. Hubert, J-P Casalta, Frédérique Gouriet, Florent Arregle, Serge Cammilleri, L. Tessonnier, Alberto Ribéri, Élisabeth Botelho-Nevers, Amandine Gagneux‐Brunon, Romain Pierrard, C. Tulane, Saveria Campisi, J-F Fuzellier, M Detoc, T Mehalla, D. Boutoille, Anne-Sophie Lecompte, M. Lefèbvre, S. Pattier, Ousama Al Habash, N Asseray-Madani, Charlotte Biron, Julia Brochard, J. Caillon, C Cueff, Thierry Le Tourneau, R. Lecomte, M. Michel, Jérémie Orain, S Delarue, M. Le Bras, J-F Faucher, Victor Aboyans, A Beeharry, H. Durox, Maximiliano Otero Lacoste, Julien Magné, Dania Mohty, Anthony S. David, V. Pradel, Victor Sierra, A. Neykova, B Bettayeb, S Elkentaoui,

Abstract Aims The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey. Methods and results Patients (n = 3116) aged over 18 years with a diagnosis of IE based on the ESC 2015 IE diagnostic criteria ...

Oxford University Press

Artigo

Michal Pazderník, Bernard Iung, Bülent Mutlu, François Alla, Robert K. Riezebos, William Kong, Maria Carmo Pereira Nunes, Luc Piérard, Ilija Srdanović, Hirotsugu Yamada, Andrea De Martino, Marcelo Haertel Miglioranza, Julien Magné, Cornelia Piper, Cécile Laroche, Aldo P. Maggioni, Patrizio Lancellotti, Gilbert Habib, Christine Selton‐Suty, Ricardo Ronderos, Gustavo Avegliano, P. Fernandez Oses, E. Filipini, Isabel Granada, Ana Iribarren, M. Mahia, Francisco Nacinovich, S. Ressi, Ramón De la Cruz Obregón, M. Bangher, J. Dho, Luis Cartasegna, M. Plastino, V Novas, C. Shigel, Graciela Reyes, Lurdes Santos, N. Gastaldello, M Granillo Fernandez, M. Potito, G. Streitenberger, P Velazco, J. H. Casabé, C. Cortes, Eduardo Guevara, Fabián Salmo, M. Seijo, F Weidinger, Maria Heger, R. Brooks, Claudia Stöllberger, C.-Y. Ho, L. Perschy, L. Puskas, Georg Goliasch, C. Binder, Raphaël Rosenhek, M Schneider, Matthew Winter, E. Hoffer, M. Melissopoulou, E Lecoq, D. Legrand, Sandrine Jacquet, M. Massoz, Patrizio Lancellotti, Luc Piérard, Raluca Dulgheru, Stella Marchetta, C. D ́Emal, Cécile Oury, B. Cosyns, Steven Droogmans, D. Kerkhove, Andreea Motoc, D. Plein, Bram Roosens, L Soens, Caroline Weytjens, I. Lemoine, Inez Rodrigus, Bernard P. Paelinck, Bram J. Amsel, Philippe Unger, D. Konopnicki, C. Beauloye, Agnès Pasquet, S Pierard, David Vancraeynest, Jean‐Louis Vanoverschelde, F. Sinnaeve, José Lázaro Andrade, Ana Clara Tude Rodrigues, Kamila Fernanda Staszko, R Dos Santos Monteiro, Marcelo Haertel Miglioranza, D. L. Shuha, M Alcantara, V Cravo, L Fazzio, Ana Félix, M. Iso, C Musa, Ana Paula dos Reis Velloso Siciliano, Fábio Villaça Guimarães Filho, Juarez R. Braga, A. Rodrigues, R. Silva, F Vilela, Daniela Laranja Gomes Rodrigues, L. Silva, Samira Saady Morhy, Cláudio Henrique Fischer, R. Silva, Marcelo Luiz Campos Vieira, T. Afonso, J. Abreu, Sandra Nívea dos Reis Saraiva Falcão, Valdir Ambrósio Moisés, A. Gouvea, G. João, Frederico Mancuso, C. Silva, Ândrea Celestino de Souza, Cely Saad Abboud, Rodrigo Bellio de Mattos Barretto, António Ramos, Renato Tambellini Arnoni, Jorge Eduardo Assef, Dorival Júlio Della Togna, David Le Bihan, L. Miglioli, A P Romero Oliveira, Roberto Tadeu Magro Kroll, Daniel Cortez, Cláudio Léo Gelape, M.d. C. Peirira Nunes, Teresa Cristina Abreu Ferrari, Kwan‐Leung Chan, Kevin A. Hay, V. Le, Mathieu Page, Frédéric Poulin, Claude Sauvé, Karim Serri, Chantal Mercure, J Beaudoin, Philippe Pîbarot, Igal A. Sebag, Lawrence Rudski, G Ricafort, Bruno Baršić, Vladimir Krajinović, Martina Vargović, J Separovic-Hanzevacki, Daniel Lovrić, V Reskovic-Luksic, Josip Vincelj, S. Jaksic Jurinjak, V Yiannikourides, Marios Ioannides, C. Kyriakou, C Pofaides, V. Masoura, K. Yiangou, Jiří Pudich, Aleš Linhart, Michal Širanec, J Marek, K Blechova, Mirt Kamenik, Michal Pazderník, Radek Pelouch, Zdeněk Coufal, M Mikulica, Martin Gřiva, Eva Jančová, M. Mikulcova, Miloš Táborský, Jan Přeček, Markéta Ječmenová, J. Latal, J Widimský, T. Butta, S. Machacek, R. Vancata, Jindřich Špinar, Mária Holická, F Pow Chon Long, N. Anzules, Arturo Carpio, G Largacha, Ernesto Peñaherrera, Davide Moreira, E. Mahfouz, E Elsafty, Ahmed M. Soliman, Yazan Zayed, J. Aboulenein, M Abdel-Hay, Abdallah Almaghraby, Mahmoud Abdelnaby, Mustafa I. Ahmed, Basma Hammad, Yehia Saleh, Hatice S. Zahran, O Elgebaly, Aly M A Saad, Mohammed Ali, A. Zeid, Reham El Sharkawy, Marwa Sayed Meshaal, A Al Kholy, Ramy Doss, Dina Osama, Hussien Rizk, A. Elmogy, M. Mishriky, Patrick Assayag, Safwane El Hatimi, Saint- E. Botelho-Nevers, Saveria Campisi, J.-F. Fuzellier, Amandine Gagneux‐Brunon, Romain Pierrard, C. Tulane, M Detoc, T Mehalla, D. Boutoille, Ousama Al Habash, N. Asseray-Madani, Charlotte Biron, J. Brochard, J. Caillon, C Cueff, T. Le Tourneau, Anne-Sophie Lecompte, R. Lecomte, M. Lefèbvre, M. Michel, S. Pattier, S Delarue, M. Le Bras, Jérémie Orain, Jean‐François Faucher, Victor Aboyans, A Beeharry, H. Durox, M. Lacoste, Julien Magné, Dania Mohty, Anthony S. David, V. Pradel, V. Sierra, A. Neykova, B. Bettayeb, S Elkentaoui, B. Tzvetkov, Gregory J. Landry, C. Strady, K. Ainine, S. Baumard, Camille Brasselet, C Tassigny, V. Valente-Pires, Marie‐Paule Lefranc, Bruno Hoen, Benjamin Lefèvre, Elodie Curlier, C. Callier, N Fourcade, Yannick Jobic, S Ansard, Rozenn Le Berre, Philippe Roux, Florent Le Ven, M-C Pouliquen, Gemma Prat, F Bouchart, A. Savouré, C. Alarçon, C. Chapuzet, I. Gueït, C. Tribouilloy, Yohann Bohbot, Fanny Peugnet, Mesut Gun, Bernard Iung, X. Duval, X. Lescure, E. Ilic-Habensus, Nicolas Sadoul, Christine Selton‐Suty, François Alla, Elodie Chevalier, François Goehringer,

High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. As compared to < 80 yo patients, ≥ 80 yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p < 0.001), of surgery performed ( ...

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Joost P. van Melle, Jolien W Roos-Hesselink, Manish Bansal, Otto Kamp, Marwa Sayed Meshaal, Jiří Pudich, Vlatka Rešković Lukšić, Regino Rodríguez, Anita Sadeghpour, Jadranka Šeparović Hanževački, Rouguiatou Sow, Ana Teresa Timóteo, Marisa Trabulo Morgado, Michele De Bonis, Cécile Laroche, Eric Boersma, Patrizio Lancellotti, Gilbert Habib, Gilbert Habib, Patrizio Lancellotti, Bernard Cosyns, Erwan Donal, Paola Anna Erba, Gilbert Habib, Bernard Iung, Aldo P. Maggioni, Bogdan A. Popescu, Bernard Prendergast, Pilar Tornos, Nora Nabila Ali Tatar-Chentir, Mouaz H. Al–Mallah, Meriam Åström Aneq, George Athanassopoulos, Luigi P. Badano, S. Benyoussef, Erick Calderón-Aranda, Nuno Cardim, Kwan‐Leung Chan, Bernard Cosyns, Ines Cruz, Thor Edvardsen, Georg Goliasch, Gilbert Habib, Andreas Hagendorff, Krasimira Hristová, Bernard Iung, Otto Kamp, Duk‐Hyun Kang, William Kong, С.Т. Мацкеплишвили, Marwa Sayed Meshaal, M Mirocevic, Aleksandar Nešković, Michal Pazderník, Edyta Płońska‐Gościniak, Bogdan A. Popescu, Bernard Prendergast, Maha Raissouni, Ricardo Ronderos, Leyla Elif Sade, Anita Sadeghpour, Antonia Sambola, Shantanu P. Sengupta, Jadranka Šeparović Hanževački, Masaaki Takeuchi, Edwin S. Tucay, Ana Clara Tude Rodrigues, Albert Varga, Jolanta Justina Vaškelytė, Kentaro Yamagata, Kyriakos Yiangou, Hosam Zaky, Ricardo Ronderos, Gustavo Avegliano, P. Fernandez Oses, E. Filipini, Isabel Granada, Ana Iribarren, M. Mahia, Francisco Nacinovich, S. Ressi, Ramón De la Cruz Obregón, M. Bangher, J. Dho, Luis Cartasegna, María Laura Plastino, V Novas, C. Shigel, Graciela Reyes, Lurdes Santos, N. Gastaldello, M Granillo Fernandez, M. Potito, G. Streitenberger, P Velazco, José Casabé, C. Cortes, Eduardo Guevara, Fabián Salmo, M. Seijo, F Weidinger, Maria Heger, R. Brooks, Claudia Stöllberger, C.-Y. Ho, L. Perschy, L. Puskas, Georg Goliasch, C. Binder, Raphaël Rosenhek, M Schneider, Matthew Winter, E. Hoffer, M. Melissopoulou, E Lecoq, D. Legrand, Sandrine Jacquet, M. Massoz, Patrizio Lancellotti, Luc Piérard, Raluca Dulgheru, Stella Marchetta, Céline D'Emal, Cécile Oury, B. Cosyns, Steven Droogmans, D. Kerkhove, Andreea Motoc, D. Plein, Bram Roosens, L Soens, Caroline Weytjens, I. Lemoine, Inez Rodrigus, Bernard P. Paelinck, Bram J. Amsel, Philippe Unger, Déborah Konopnicki, C. Beauloye, Agnès Pasquet, S Pierard, David Vancraeynest, Jean‐Louis Vanoverschelde, F. Sinnaeve, José Lázaro Andrade, Ana Clara Tude Rodrigues, Kamila Fernanda Staszko, R Dos Santos Monteiro, Marcelo Haertel Miglioranza, D. L. Shuha, M Alcantara, V Cravo, L Fazzio, Ana Félix, M. Iso, C Musa, Ana Paula dos Reis Velloso Siciliano, Fábio Villaça Guimarães Filho, Juarez R. Braga, Ana Clara Tude Rodrigues, R. Silva, F Vilela, Daniela Laranja Gomes Rodrigues, L Silva, Samira Saady Morhy, Cláudio Henrique Fischer, R. Silva, Marcelo Luiz Campos Vieira, T. Afonso, J. Abreu, Sandra Nívea dos Reis Saraiva Falcão, Valdir Ambrósio Moisés, A. Gouvea, G. João, Frederico Mancuso, C. Silva, Ana Carolina Mello Fontoura de Souza, Cely Saad Abboud, Rodrigo Bellio de Mattos Barretto, António Ramos, Renato Tambellini Arnoni, Jorge Eduardo Assef, Dorival Júlio Della Togna, David Le Bihan, L. Miglioli, A P Romero Oliveira, Roberto Tadeu Magro Kroll, Daniel Cortez, Cláudio Léo Gelape, M d C Peirira Nunes, Teresa Cristina Abreu Ferrari, Kwan‐Leung Chan, Kevin A. Hay, V. Le, Mathieu Page, Frédéric Poulin, Claude Sauvé, Karim Serri, Chantal Mercure, J Beaudoin, Philippe Pîbarot, Igal A. Sebag, Lawrence Rudski, G Ricafort, Bruno Baršić, Vladimir Krajinović, Martina Vargović, Jadranka Šeparović Hanževački, Daniel Lovrić, V Reskovic-Luksic, Josip Vincelj, S. Jaksic Jurinjak, V Yiannikourides, Marios Ioannides, C. Kyriakou, C Pofaides, V. Masoura, K. Yiangou, Jiří Pudich, Aleš Linhart, Michal Širanec, J Marek, K Blechova, Mirt Kamenik, Michal Pazderník, Radek Pelouch, Zdeněk Coufal, M Mikulica, Martin Gřiva, Eva Jančová, M. Mikulcova, Miloš Táborský, Jan Přeček, Markéta Ječmenová, J. Latal, J Widimský, T. Butta, S. Machacek, R. Vancata, Jindřich Špinar, Mária Holická, F Pow Chon Long, N. Anzules, Arturo Carpio, G Largacha, Ernesto Peñaherrera, Davide Moreira, E. Mahfouz, E Elsafty, Ahmed M. Soliman, Yazan Zayed, J. Aboulenein, M Abdel-Hay, Abdallah Almaghraby, Mahmoud Abdelnaby, Mustafa I. Ahmed, Basma Hammad, Yehia Saleh, Hatice S. Zahran, O Elgebaly, Aly M A Saad, Mohammed Ali, A. Zeid, Reham El Sharkawy, Marwa Sayed Meshaal, A Al Kholy, Ramy Doss, Dina Osama, Hussien Rizk, A. Elmogy, M. Mishriky, Patrick Assayag, Safwane El Hatimi, Élisabeth Botelho-Nevers, Saveria Campisi, J.-F. Fuzellier, Amandine Gagneux‐Brunon, Romain Pierrard, C. Tulane, M Detoc, T Mehalla, D. Boutoille, Ousama Al Habash, N. Asseray-Madani, Charlotte Biron, J. Brochard, J. Caillon, C Cueff, Thierry Le Tourneau, Anne-Sophie Lecompte, R. Lecomte, M. Lefèbvre, M. Michel, S. Pattier, S Delarue, M. Le Bras,

BackgroundCongenital Heart Disease (CHD) predisposes to Infective Endocarditis (IE), but data about characterization and prognosis of IE in CHD patients is scarce.MethodsThe ESC-EORP-EURO-ENDO study is a prospective international study in IE patients (n = 3111). In this pre-specified analysis, adult CHD patients (n = 365, 11.7%) are described and compared with patients without CHD (n = 2746) in terms of baseline characteristics and mortality.ResultsCHD patients (73% men, age 44.8 ± 16.6 years) were younger and ...

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