A. Ferreira Dos Santos, A. Ferreira Dos Santos,
... Eis Um Motivo Porque É Tão Séria, Conselheiro Leonel Cardoso, On the Water for Beira, The Monomotapa Concessions, ...
1908 - Gale Group | NCCO EuropeAfrica
Verónica C. Martins, J. Germano, Filipe A. Cardoso, Joana Loureiro, Susana Cardoso, Leonel Sousa, M.S. Piedade, Luís P. Fonseca, P. P. Freitas,
The magnetoresistive (MR) biochip concept has emerged a decade ago and since then considerable achievements were made in the field. At the moment there is a strong effort in building up a fully integrated, portable and accessible spintronic device for bioanalytical assays. Some of the major challenges and working solutions are addressed here. In a MR-biochip platform five main components can be identified as key points for its success: the MR sensing elements, the magnetic labels, the surface chemistry, ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2009 - Elsevier BV | Journal of Magnetism and Magnetic Materials
V. C. Martins, Filipe A. Cardoso, J. Germano, Susana Cardoso, Leonel Sousa, M.S. Piedade, P. P. Freitas, Luís P. Fonseca,
In this paper the biological limit of detection of a spin-valve-based magnetoresistive biochip applied to the detection of 20 mer ssDNA hybridization events is presented. Two reactional variables and their impact on the biomolecular recognition efficiency are discussed. Both the influence of a 250 nm diameter magnetic particle attached to the target molecule during the hybridization event and the effect of a magnetic focusing system in the hybridization of pre-labeled target DNA (assisted hybridization) ...
Tópico(s): Electrochemical Analysis and Applications
2009 - Elsevier BV | Biosensors and Bioelectronics
Filipe S. Cardoso, Leonel Ricardo, A M Oliveira, Jorge Canena, David Horta, Ana Luísa Papoila, J. Ramos de Deus,
C-reactive protein (CRP) has been used widely in the early risk assessment of patients with acute pancreatitis. This study evaluated the prognostic accuracy of CRP for severe acute pancreatitis (SAP), pancreatic necrosis (PNec), and in-hospital mortality (IM) in terms of the best timing for CRP measurement and the optimal CRP cutoff points.This was a single-center retrospective cohort study including 379 patients consecutively admitted with acute pancreatitis. CRP determinations at hospital admission, ...
Tópico(s): Appendicitis Diagnosis and Management
2013 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Vítor Cardoso, Leonel Queimada,
The "cosmic censorship conjecture" asserts that all singularities arising from gravitational collapse are hidden within black holes. We investigate this conjecture in a setup of interest for tests of general relativity: black hole solutions which are parametrically small deviations away from the Kerr solution. These solutions have an upper bound on rotation, beyond which a naked singularity is visible to outside observers. We study whether these (generic) spacetimes can be spun-up past extremality ...
Tópico(s): Cosmology and Gravitation Theories
2015 - Springer Science+Business Media | General Relativity and Gravitation
Filipe S. Cardoso, Leonel Ricardo, Ana Oliveira, David Horta, Ana Luísa Papoila, J. Ramos de Deus, Jorge Canena,
C-reactive protein (CRP) and Bedside Index for Severity in Acute Pancreatitis (BISAP) have been used in early risk assessment of patients with AP.
Tópico(s): Gastrointestinal disorders and treatments
2015 - Karger Publishers | GE Portuguese Journal of Gastroenterology
Produção Nacional
Bruno Homann Zilli, Melise de Lima Pereira, Wellyngton Fernando Leonel de Souza, GUTEMBERG CARDOSO DA SILVA,
By analyzing the tourist demand of destinations and understanding the changes occurring in the tourism sector for various reasons, it becomes possible to elucidate tourists' desires, evaluate their perception regarding the products and services offered, and identify the need for adaptation on the part of business owners and public managers. In this perspective, this study aims to address the following question: how can measurement indicators of tourist experience be used in a research instrument ...
Tópico(s): Cruise Tourism Development and Management
2023 - UNIVERSIDADE DO VALE DO ITAJAÍ | Applied Tourism
António Coelho, Rui Rodrigues, Rui Nóbrega, João Jacob, Leonel Morgado, Pedro Cardoso, Maria van Zeller, Liliana Santos, António Augusto de Sousa,
Serious Pervasive Games extend the “magic circle” to the players’ surrounding environment. The blend of both physical and fictive game worlds provides a push in player engagement and promotes situated learning approaches. Space and time, as well as social context, acquire a more meaningful impact on the gameplay. From pervasive learning towards science communication with location-based games, this article presents case studies that exemplify their benefits and related problems. Pervasive learning ...
Tópico(s): Teaching and Learning Programming
2020 - Frontiers Media | Frontiers in Computer Science
Produção Nacional
Revisado por pares
Natanael Victor Furtunato Bezerra, KF Leite, Mariana Marinho Davino de Medeiros, Mariana Leonel Martins, Andréia Medeiros Rodrigues Cardoso, Pollianna Muniz Alves, Wílton Wilney Nascimento Padilha, Yuri Wanderley Cavalcanti,
To evaluate the prevalence of oral cancer in Brazil according to the clinical stage, anatomical location, alcoholism and smoking.Data referring to 31,217 cases of oral cancer, from 2000 to 2010, were obtained from the Integrator Module of the Hospital Registry of Cancer. Inconsistent data ("non-classified" cases) was eliminated and 21,160 cases were analyzed. The frequency distribution according to clinical stage, anatomical location, alcoholism and smoking was analyzed descriptively and through a ...
Tópico(s): Oral health in cancer treatment
2018 - Medicina Oral S.L. | Medicina oral, patología oral y cirugía bucal
Produção Nacional
Revisado por pares
Carlos Mazariegos-Ortíz, María de los Ángeles Rosales, Leonel Carrillo-Ovalle, Renan Pereira Cardoso, Marcelo Costa Muniz, R. M. Anjos,
In Guatemala, assessment of the impacts of microplastic pollution in marine and coastal protected areas has not yet been carried out. Therefore, the main goal of this paper was to evaluate the abundance, composition, physical forms, and the possible sources of plastic debris in the El Quetzalito Beach. The area was intended for biodiversity conservation but has been excessively contaminated by plastic materials from land-based activities. The results state that plastic debris negatively impact the ...
Tópico(s): biodegradable polymer synthesis and properties
2020 - Elsevier BV | Marine Pollution Bulletin
Produção Nacional
Revisado por pares
Christiano Bruneli Peres, Pedro R. Resende, Leonel J. R. Nunes, Leandro Cardoso de Morais,
One of society’s major current challenges is carbon dioxide emissions and their consequences. In this context, new technologies for carbon dioxide (CO2) capture have attracted much attention. One of these is carbon capture and utilization (CCU). This work focuses on the latest trends in a holistic approach to carbon dioxide capture and utilization. Absorption, adsorption, membranes, and chemical looping are considered for CO2 capture. Each CO2 capture technology is described, and its benefits and ...
Tópico(s): Carbon dioxide utilization in catalysis
2022 - Multidisciplinary Digital Publishing Institute | Clean Technologies
Produção Nacional
Revisado por pares
Viviane Silva Siqueira-Sandrin, Gabriela Moraes Oliveira, Giovana Maria Weckwerth, Nelson Leonel Del Hierro Polanco, Flávio Augusto Cardoso de Faria, Carlos Ferreira Santos, Adriana Maria Calvo,
The aim of this study was to carry out a systematic investigation and analysis of different drug extraction methods, specifically non-steroidal anti-inflammatory drugs in biological fluid samples, for Liquid Chromatography in Mass Spectrometry assays (LC-MS/MS). A search was carried out in the main databases between 1999 and 2021, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. Data were obtained through PubMed, ...
Tópico(s): Forensic Toxicology and Drug Analysis
2022 - Multidisciplinary Digital Publishing Institute | Metabolites
André Oliveira, Tiago Mestre, Leonel Ricardo, Ana Maria Rodrigues, Jorge Cardoso,
Pancreatic panniculitis is a rare complication of pancreatic disease occurring in 2% to 3% of all patients, most commonly those with acute or chronic pancreatitis.We report the case of a pancreatic panniculitis associated with acute pancreatitis in a 63-year-old man. He presented with a 2-day history of multiple tender subcutaneous nodules, followed by nausea, vomiting, severe epigastric pain and loss of appetite, hours before admission. Laboratory and radiologic findings revealed acute pancreatitis. ...
Tópico(s): Parvovirus B19 Infection Studies
2014 - | Journal of Dermatological Case Reports
Produção Nacional
Revisado por pares
Leonel Quinteros, Viviana Meruane, Eduardo Lenz Cardoso,
Tópico(s): Topology Optimization in Engineering
2021 - Springer Science+Business Media | Structural and Multidisciplinary Optimization
Filipe S. Cardoso, Leonel Ricardo, Pedro Gondar, J. Ramos de Deus, David Horta,
Prescription of prophylactic antibiotics in acute pancreatitis (AP) is controversial. We aimed to identify the patients' characteristics that may prompt clinicians to prescribe prophylactic antibiotics in AP.This single-center retrospective cohort study included 299 consecutive patients with AP from a Portuguese hospital in 2009 to 2010. Logistic regression was used to study the association of patients' characteristics with prescription of prophylactic antibiotics in AP.Persistent organ failure developed ...
Tópico(s): Appendicitis Diagnosis and Management
2014 - Lippincott Williams & Wilkins | Pancreas
Produção Nacional
Revisado por pares
Leonel Quinteros, Viviana Meruane, Eduardo Lenz Cardoso, Rafael O. Ruiz,
The development of custom cellular materials has been driven by recent advances in additive manufacturing and structural topological optimization. These contemporary materials with complex topologies have better structural efficiency than traditional materials. Particularly, truss-like cellular structures exhibit considerable potential for application in lightweight structures owing to their excellent strength-to-mass ratio. Along with being light, these materials can exhibit unprecedented vibration ...
Tópico(s): Noise Effects and Management
2021 - Multidisciplinary Digital Publishing Institute | Materials
J. Germano, Verónica C. Martins, Filipe A. Cardoso, T. M. Almeida, Leonel Sousa, P. P. Freitas, M.S. Piedade,
This paper presents a prototype of a platform for biomolecular recognition detection. The system is based on a magnetoresistive biochip that performs biorecognition assays by detecting magnetically tagged targets. All the electronic circuitry for addressing, driving and reading out signals from spin-valve or magnetic tunnel junctions sensors is implemented using off-the-shelf components. Taking advantage of digital signal processing techniques, the acquired signals are processed in real time and ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2009 - Multidisciplinary Digital Publishing Institute | Sensors
Produção Nacional
Revisado por pares
Leonel Alves do Nascimento, Mariana Guimarães Cardoso, Samuel Andrade de Oliveira, Eliane Quina, Denise da Silva Scaneiro Sardinha,
RESUMO JUSTIFICATIVA E OBJETIVOS: A dor é o principal motivo de procura por atendimento nos serviços de saúde. Dessa forma, este estudo teve como objetivo conhecer as práticas utilizadas por profissionais de saúde em relação ao manuseio da dor em um hospital público de nível secundário do norte do Paraná. MÉTODOS: Pesquisa descritiva e exploratória com enfoque quantitativo, realizada no período de março a maio de 2015, por meio de um questionário semiestruturado. Participaram do estudo 112 profissionais ...
Tópico(s): Health, Nursing, Elderly Care
2016 - Sociedade Brasileira para o Estudo da Dor | Revista Dor
Produção Nacional
Revisado por pares
Silvia Lins, Kléber V. Cardoso, Cristiano Bonato Both, Luciano Leonel Mendes, José Ferreira de Rezende, Antônio Morais da Silveira, Neiva Linder, Aldebaro Klautau,
In the context of Fifth Generation mobile networks (5G), Search and Rescue (SAR) missions using Unmanned Aerial Vehicles (UAVs) can benefit from a dynamic, intelligent, and autonomous placement of both Network Functions (NFs) and Artificial Intelligence (AI) systems to quickly adapt in minimal human intervention scenarios. This article examines current 5G architectures and timely standardization efforts within this context. The contribution of this work is to identify associated 5G components and propose ...
Tópico(s): Satellite Communication Systems
2021 - Institute of Electrical and Electronics Engineers | IEEE Access
Produção Nacional
Revisado por pares
Herbert Leonel de Matos Guedes, João M. Rezende Neto, Mayra A. Fonseca, Cristiane Martins Cardoso de Salles, Bartira Rossi‐Bergmann, Salvatore G. De-Simone,
Leishmania (V.) braziliensis is one of the most important ethiologic agents of the two distinct forms of American tegumentary leishmaniasis (cutaneous and mucosal). The drugs of choice used in leishmaniasis therapy are significantly toxic, expensive and are associated with frequent refractory infections. Among the promising new targets for anti-protozoan chemotherapy are the proteases. In this study, serine proteases were partially purified from aqueous, detergent and extracellular extracts of Leishmania ...
Tópico(s): Research on Leishmaniasis Studies
2007 - De Gruyter | Zeitschrift für Naturforschung C
Produção Nacional
Revisado por pares
Talita Mayra Resende Ferreira, Alda Jusceline Leonel, Marco Melo, Rosana R. G. Santos, Denise Carmona Cara, Valbert Nascimento Cardoso, María Isabel Toulson Davisson Correia, Jacqueline I. Alvarez‐Leite,
Mucositis affects about 40 % of patients undergoing chemotherapy. Short chain fatty acids (SCFA), mainly butyrate, are claimed to improve mucosal integrity, reduce intestinal permeability and act as anti-inflammatory agents for the colon mucosa. We evaluated the effects of oral administration of SCFA or butyrate in the 5FU-induced mucositis. Mice received water, SCFA or butyrate during all experiment (10 days) and a single dose of 5FU (200 mg/kg) 3 days before euthanasia. We evaluated inflammatory and ...
Tópico(s): Head and Neck Cancer Studies
2012 - Wiley | Lipids
Produção Nacional
Revisado por pares
Maísa Mota Antunes, Paola Caroline Lacerda Leocádio, Lílian Gonçalves Teixeira, Alda Jusceline Leonel, Denise Carmona Cara, Gustavo Batista Menezes, Simone de Vasconcelos Generoso, Valbert Nascimento Cardoso, Jacqueline I. Alvarez‐Leite, María Isabel Toulson Davisson Correia,
Background: Mucositis is a common complication in patients undergoing radiotherapy and chemotherapy. It is associated with pain, poor quality of life, and malnutrition, leading to an increased number of hospital admissions and prolonged hospitalization. The use of immunonutrients may be an alternative treatment option, which may help to improve patient outcome. Objective : Here we assessed the impact of L‐citrulline (CIT) on a murine model of 5‐fluorouracil (5FU)–induced mucositis. Methods : Swiss male ...
Tópico(s): Neutropenia and Cancer Infections
2015 - Wiley | Journal of Parenteral and Enteral Nutrition
Produção Nacional
Revisado por pares
Natanael Victor Furtunato Bezerra, Karla Lorene de França Leite, Mariana Marinho Davino de Medeiros, Mariana Leonel Martins, Andréia Medeiros Rodrigues Cardoso, Cassiano Francisco Weege Nonaka, Wílton Wilney Nascimento Padilha, Yuri Wanderley Cavalcanti,
Tópico(s): Viral-associated cancers and disorders
2017 - Springer Science+Business Media | Journal of Public Health
Produção Nacional
Revisado por pares
Paola Caroline Lacerda Leocádio, Maísa Mota Antunes, Lílian Gonçalves Teixeira, Alda Jusceline Leonel, Jacqueline I. Alvarez‐Leite, Denise Carmona Cara Machado, Simone V. Generoso, Valbert Nascimento Cardoso, María Isabel Toulson Davisson Correia,
Beneficial effects of L-arginine on immune responses and bowel function have been reported. Mucositis is a side effect of chemotherapy treatment that affects approximately 40% of patients. This complication is characterized by inflammation that affects the gastrointestinal tract, increasing permeability and causing abdominal pain, nausea, vomiting, and diarrhea, which worsen the patient's nutritional status and increases morbimortality. The aim of this study was to evaluate the effect of pretreating ...
Tópico(s): Neutropenia and Cancer Infections
2015 - Routledge | Nutrition and Cancer
Produção Nacional
Gilmar dos Santos Cardoso, Leonel da Silva Rodrigues, Diego Soares Machado, Camille Carijo Domingues, Mauren Burin da Silva, Patrícia Machado Martini, Sander Martinho Adams, Daniele Borchate, Ivan Luiz Brondani, Dari Celestino Alves Filho,
The objective of this study was to evaluate the effect of crude protein substitution of soybean meal with urea (slow-release or otherwise) on the carcass and the meat characteristics of finished steers in confinement. Twenty-seven castrated, purebred and Charolais-Nelore crossbred steers with a mean age of 20 ± 1,5 months and initial mean live weight of 293 ± 31 kg, were distributed in three treatments: Protected Urea (concentrate containing slow degradation urea ); Soybean meal (concentrate containing soybean ...
Tópico(s): Genetic and phenotypic traits in livestock
2019 - UNIVERSIDADE ESTADUAL DE LONDRINA | Semina Ciências Agrárias
Produção Nacional
Rodrigo Rezende, Igor Machado Cardoso, Rayana Bomfim Leonel, Larissa Grobério Lopes Perim, Tarcísio Guimarães Silva Oliveira, Chárbel Jacob Júnior, José Lucas Batista Júnior, Rafael Burgomeister Lourenço,
To evaluate bone mineral density among patients with neuromuscular scoliosis secondary to quadriplegic cerebral palsy. This was a descriptive prospective study in which both bone densitometric and anthropometric data were evaluated. The inclusion criteria used were that the patients should present quadriplegic cerebral palsy, be confined to a wheelchair, be between 10 and 20 years of age and present neuromuscular scoliosis. We evaluated 31 patients (20 females) with a mean age of 14.2 years. Their ...
Tópico(s): Bone and Joint Diseases
2014 - Brazilian Society of Orthopedics and Traumatology | Revista Brasileira de Ortopedia (English Edition)
Produção Nacional
Leonel Tadao Takada, Valéria Santoro Bahia, Henrique Cerqueira Guimarães, Thaís Virgínia Moura Machado Costa, Thiago Cardoso Vale, Roberta Diehl Rodriguez, Fábio H.G. Porto, João Carlos Machado, Rogério Beato, Karolina Gouveia César‐Freitas, Jerusa Smid, Camila Nascimento, Lea T. Grinberg, Sônia Maria Dozzi Brucki, Jéssica Ruivo Maximino, Sarah Camargos, Gerson Chadi, Paulo Caramelli, Ricardo Nitríni,
Background: Mutations in GRN (progranulin) and MAPT (microtubule-associated protein tau) are among the most frequent causes of monogenic frontotemporal dementia (FTD), but data on the frequency of these mutations in regions such as Latin America are still lacking. Objective: We aimed to investigate the frequencies of GRN and MAPT mutations in FTD cohorts from 2 Brazilian dementia research centers, the University of Sao Paulo and the Federal University of Minas Gerais medical schools. Methods: We included ...
Tópico(s): Alzheimer's disease research and treatments
2016 - Lippincott Williams & Wilkins | Alzheimer Disease & Associated Disorders
Luís Fernandes, Gonçalo Cruz, Diogo Azevedo, Ricardo Rodrigues Nunes, Hugo Paredes, Leonel Morgado, Luís Barbosa, Paulo Martins, Benjamim Fonseca, Paulo Cristóvão, Fausto de Carvalho, Bernardo Cardoso,
Gestural interaction devices emerged and originated various studies on multimodal human–computer interaction to improve user experience (UX). However, there is a knowledge gap regarding the use of these devices to enhance learning. We present an exploratory study which analysed the UX with a multimodal immersive videogame prototype, based on a Portuguese historical/cultural episode. Evaluation tests took place in high school environments and public videogaming events. Two users would be present simultaneously ...
Tópico(s): Augmented Reality Applications
2016 - Taylor & Francis | Behaviour and Information Technology
Produção Nacional
Revisado por pares
Lorena Lopes Ferreira, Jéssica Martins de Andrade, William Gustavo Lima, Juliano De P. Souza, Rafael César Russo Chagas, Camyla A. Leonel, Laís Cardoso Cunha, Karina Marjorie Silva Herrera, Alysson V. Braga, Luís Fernando Soares, Jaqueline Maria Siqueira Ferreira,
The emergence of antibiotic resistance among microbial pathogens is a serious public health problem, resulting in a constant need of discovering new antibiotics.For this purpose, we synthetized and determined the antimicrobial activity of copper (Cu), cobalt (Co), and tin (Sn) complexes coordinated with scorpionate ligand in a tridentate mode against microorganisms of clinical importance.New complexes with the sodium hydrotris(2-mercaptothiazolyl)borate ligand were characterized by physicochemical ...
Tópico(s): Inorganic and Organometallic Chemistry
2020 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Christiano Bruneli Peres, Pedro R. Resende, Leonel J. R. Nunes, Leandro Cardoso de Morais,
The growing increase in greenhouse gases, especially carbon dioxide (CO2), by anthropogenic activities can be linked to extreme climate events, such as intensive droughts, floods, or hurricanes, and has led to several studies focused on reducing the concentration of this greenhouse gas in the atmosphere. Some technologies, such as carbon capture and storage (CCS), can potentially sequester billions of tons of CO2 per year. One of the promising methods is the use of carbon mineralization as a CCS methodology. ...
Tópico(s): Carbon Dioxide Capture Technologies
2022 - Multidisciplinary Digital Publishing Institute | Sustainability