Nancy R. Sturm, David A. Campbell,
... Scholar) because these results contrasted with findings in Leptomonas (12Lücke S. Xu G.L. Palfi Z. Cross ... PubMed Scopus (48) Google Scholar) but not in Leptomonas (12Lücke S. Xu G.L. Palfi Z. Cross ... not content, of stem-loop III. Studies in Leptomonas seymouridemonstrated that mutation of a variety of elements ... Our data broadly contrast the results obtained in Leptomonas, where the structure and not the primary sequence ... consistent with results from a similar study in Leptomonas (12Lücke S. Xu G.L. Palfi Z. Cross ...
Tópico(s): Viral Infections and Immunology Research
1999 - Elsevier BV | Journal of Biological Chemistry
Indira Singh Chauhan, Jaspreet Kaur, Shagun Krishna, Arpita Ghosh, Prashant Singh, Mohammad Imran Siddiqi, Neeloo Singh,
Abstract Background Leptomonas is monogenetic kinetoplastid parasite of insects and is primitive in comparison to Leishmania . Comparative studies of these two ... proteins. Results During change of lifestyle from monogenetic ( Leptomonas ) to digenetic ( Leishmania ), we found that the prenyl ... was absent in both Leishmania and its sister Leptomonas. Farnesyltransferase (FTase) and geranylgeranyl transferase-II (GGTase-II) ... alpha-subunit (α-subunit) of GGTase-II in Leptomonas was probably contributed by the α-subunit of ...
Tópico(s): Biochemical and Molecular Research
2015 - Springer Science+Business Media | BMC Evolutionary Biology
Cyrus J. Bacchi, C. Lambros, Burt Goldberg, S. H. Hutner, Gabriel Domingos Carvalho,
... of the lower trypanosomatids Crithidia fasciculata and a Leptomonas from a hemipteron by several established trypanocides and ... in four complex and one defined media. The Leptomonas was more susceptible than C. fasciculata in all ... these drugs required for 50% inhibition of the Leptomonas were <5 μg/ml. In contrast, C. fasciculata ... was three- to sixfold less susceptible than the Leptomonas to isometamidium and prothidium. Both trypanosomatids were susceptible ... by suramin, melarsen, melarsen oxide, or tryparsamide. The Leptomonas was more susceptible to standard trypanocides than five ...
Tópico(s): Insect-Plant Interactions and Control
1974 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Angamuthu Selvapandiyan, Kavita Ahuja, Niti Puri, Anuja Krishnan,
... recent years co-infection of another Trypanosomatid parasite Leptomonas with L. donovani during VL/PKDL in this ... The observation of clinically lesser-known insect parasite, Leptomonas in leishmaniasis is intriguing to researchers. The presence of Leishmania look alike Leptomonas in the cultures of clinical isolates of Leishmania ... elevate mortality, need a thorough investigation. Also whether Leptomonas is involved in leishmaniasis manifestation needs to be ...
Tópico(s): Trypanosoma species research and implications
2015 - Cambridge University Press | Parasitology
Neeloo Singh, Surendra K. Chikara, Shyam Sundar,
... Azar (visceral leishmaniasis) cases were genetically related to Leptomonas. The co-infection in splenic aspirate of these patients with a species of Leptomonas and how likely is it that the infection ... Kala Azar found to be most similar to Leptomonas species put forth important clinical implications for the treatment of Kala Azar in India. Leptomonas have been shown to be highly susceptible to ...
Tópico(s): Research on Leishmaniasis Studies
2013 - Public Library of Science | PLoS ONE
Pankaj Srivastava, Vijay Kumar Prajapati, Manu Vanaerschot, Gert Van der Auwera, Jean‐Claude Dujardin, Shyam Sundar,
... rRNA gene sequencing to be most similar to Leptomonas species. One of these isolates was used to ... PCR analysis: this revealed the presence of both Leptomonas sp. and Leishmania donovani. Therefore, we conclude that there was a mixed infection of Leptomonas sp. and L. donovani in this isolate. We ... infection may be present in the patients themselves, Leptomonas persisting in them because of the immuno-suppression ...
Tópico(s): Insect Pest Control Strategies
2010 - Elsevier BV | Infection Genetics and Evolution
Vyacheslav Yurchenko, Julius Lukeš, Xing Xu, Dmitri Maslov,
ABSTRACT. Leptomonas podlipaevi n. sp., a new trypanosomatid species, is described herein based on light microscopic, ultrastructural, and molecular ... the new species is most closely related to Leptomonas seymouri and Leptomonas pyrrhocoris . The analysis has also highlighted the polyphyly of the genus Leptomonas .
Tópico(s): Insect symbiosis and bacterial influences
2006 - Wiley | Journal of Eukaryotic Microbiology
Xue‐hai Liang, Avivit Ochaion, Yuxin Xu, Qing Liu, Shulamit Michaeli,
... this study, we characterized four snoRNA clusters in Leptomonas collosoma. All of the clusters analyzed carry both ... this study, we characterized four snoRNA clusters in Leptomonas collosoma. All of the clusters analyzed carry both ... Scholar). The first C/D snoRNA identified in Leptomonas collosoma was termed snoRNA-2 and was shown ... the T7 opposing system. However, in Leishmania and Leptomonas, the silencing was elicited by antisense RNA. We ...
Tópico(s): RNA and protein synthesis mechanisms
2004 - Elsevier BV | Journal of Biological Chemistry
Herzel Ben-Shlomo, Alexander Levitan, Naomi Editha Shay, И. Н. Гончаров, Shulamit Michaeli,
Analysis of the trypanosomatid Leptomonas collosoma 7SL RNA revealed the existence of two distinct stable 7SL RNA conformers (7SL I and II). Sequence analysis of ... 7SL RNA in vivo. Analysis of the trypanosomatid Leptomonas collosoma 7SL RNA revealed the existence of two ... between the 7SL RNAs of the monogenetic trypanosomatid Leptomonas collosoma and Trypanosoma brucei (13Ben-Shlomo H. Levitan ... between the 7SL RNAs of the monogenetic trypanosomatid Leptomonas collosoma and Trypanosoma brucei (13Ben-Shlomo H. Levitan ...
Tópico(s): Research on Leishmaniasis Studies
1999 - Elsevier BV | Journal of Biological Chemistry
Kavita Ahuja, Ginni Arora, Prashant Khare, Angamuthu Selvapandiyan,
Leishmania and Leptomonas are protozoan parasites of the family Trypanosomatidae. Leishmania donovani causes the fatal visceral leishmaniasis (VL; kala-azar) in ... leishmaniasis (PKDL) due to the same parasite. Although Leptomonas is parasitic mainly in insects, several recent reports ... PKDL patients in India confirm co-infection of Leptomonas seymouri, probably due to immune suppression in those ...
Tópico(s): Trypanosoma species research and implications
2015 - Elsevier BV | Parasitology International
Michal Mandelboim, Carlos Lopez Estraño, Christian Tschudi, Elisabetta Ullu, Shulamit Michaeli,
... we present a mutational analysis of the trypanosomatid Leptomonas collosoma SL RNA to further our understanding of ... we present a mutational analysis of the trypanosomatid Leptomonas collosoma SL RNA to further our understanding of ... for details). In our laboratory we use the Leptomonas collosoma system to examine structural-functional aspects of ...
Tópico(s): Trypanosoma species research and implications
2002 - Elsevier BV | Journal of Biological Chemistry
Ekaterina M. Merzlyak, Vyacheslav Yurchenko, Alexander Kolesnikov, Kirill Alexandrov, S. A. Podlipaev, Dmitri Maslov,
... from ten isolates, which were originally classified as Leptomonas, Blaslocrithidia , and Wallaceina based on their morphology in ... likelihood, parsimony, and distance trees indicate that the Leptomonas and Blastocrithidia are polyphyletic, and confirm the polyphyly of Herpetomonas and Crithidia. Blaslocrithidia triatoma and Leptomonas collosoma were among the earliest branching lineages among ...
Tópico(s): Insect-Plant Interactions and Control
2001 - Wiley | Journal of Eukaryotic Microbiology
Produção Nacional
Revisado por pares
Alexandre Romeiro, Antônio M. Solé‐Cava, Maria Alice Pereira de Sousa, Wanderley de Souza, Márcia Attias,
... indicated that this trypanosomatid belongs to the genus Leptomonas . The molecular karyotype of this isolate was compared with that of a strain of Leptomonas oncopelti obtained from Oncopeltus varicolor by contour‐clamped ... identical. Based on our findings we are describing Leptomonas wallacei n. sp. for our isolate from O. ...
Tópico(s): Legume Nitrogen Fixing Symbiosis
2000 - Wiley | Journal of Eukaryotic Microbiology
Liu Li, Leo R. Otake, Yuxin Xu, Shulamit Michaeli,
... report the cloning of U4 snRNA gene from Leptomonas collosoma and analysis of elements controlling its expression. ... report the cloning of U4 snRNA gene from Leptomonas collosoma and analysis of elements controlling its expression. ... sequenced the U4 gene from the monogenetic trypanosomatid Leptomonas collosoma. This completes the set of spliceosomal RNAs ...
Tópico(s): Biochemical and Molecular Research
2000 - Elsevier BV | Journal of Biological Chemistry
С. А. Булат, Igor Mokrousov, S. A. Podlipaev,
... except for Wallaceina branch and two species of Leptomonas genera are quite distant from each other and ... Wallaceina together with two others isolates and two Leptomonas formed separate groups. Therefore, separate taxon status for Wallaceina and two Leptomonas species as well as heterogeneity of Leptomonas, Herpetomonas and Crithidia genera are proposed. The low ...
Tópico(s): Trypanosoma species research and implications
1999 - Elsevier BV | European Journal of Protistology
... spliced leader (SL). The SL RNA gene in Leptomonas seymouri is a member of the small nuclear ... spliced leader (SL). The SL RNA gene in Leptomonas seymouri is a member of the small nuclear ... RNA gene. The marked gene was reintroduced into Leptomonas seymouri, an easily manipulated trypanosomatid, using a stably ... 9Crossref PubMed Google Scholar). Our data suggest the Leptomonas PBP-1 protein may be analogous to SNAPc/ ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
1997 - Elsevier BV | Journal of Biological Chemistry
David Hartree, Vivian Bellofatto,
... a stable episome transfected into the monogenetic trypanosomatid Leptomonas seymouri. We now identify components of the MX ... in a tagged MX gene were transfected into Leptomonas on an episomal vector. Expression of tagged and ... sequence-specific blocks within this 70-bp region. Leptomonas cell extracts contain protein(s) that appear to ...
Tópico(s): Viral Infections and Immunology Research
1995 - Elsevier BV | Molecular and Biochemical Parasitology
Produção Nacional
Revisado por pares
José O. Previato, Lúcia Mendonça‐Previato, Christopher Jones, Robin Wait, Bernard Fournet,
Aqueous phenol extraction of the lower trypanosomatid Leptomonas samueli released into the aqueous layer a chloroform/methanol/water-soluble glycophosphosphingolipid fraction. Alkaline degradation and purification by gel filtration chromatography resulted in ... the lipopeptidophosphoglycan of Trypanosoma cruzi. The glycophosphosphingolipids of Leptomonas have features in common with the glycolipids of ... both T. cruzi and Leishmania evolved from a Leptomonas-like ancestor.
Tópico(s): Lysosomal Storage Disorders Research
1992 - Elsevier BV | Journal of Biological Chemistry
SYNOPSIS. Defined media for Leptomonas collosoma, L. mirabilis , and L. sp. from Dysdercus are described. In addition to factors required by Crithidia spp., including a ... of Crithidia factor, all 3 organisms require glycine. Leptomonas collosoma and L. sp. from Dysdercus require choline. ... but L. collosoma has an especially large requirement. Leptomonas mirabilis but not L . sp. from Dysdercus can ...
Tópico(s): Insect and Pesticide Research
1966 - Wiley | The Journal of Protozoology
Lovlesh Thakur, Hemant R. Kushwaha, Ajeet Kumar Negi, Aklank Jain, Manju Jain,
... leishmaniasis patients. Interestingly, we found the presence of Leptomonas seymouri in 38.5% (22/57) of the ... an urgent need to understand the biology of Leptomonas co-infection with L. donovani and its possible ...
Tópico(s): Trypanosoma species research and implications
2020 - Frontiers Media | Frontiers in Cellular and Infection Microbiology
Pavel Flegontov, Anzhelika Butenko, Sergei Firsov, Natalya Kraeva, Marek Eliáš, Mark C. Field, Dmitry A. Filatov, Olga Flegontova, Evgeny S. Gerasimov, Jana Hlaváčová, Aygul Ishemgulova, Andrew P. Jackson, Steven Kelly, Alexei Yu. Kostygov, Maria D. Logacheva, Dmitri Maslov, Fred R. Opperdoes, Amanda O’Reilly, Jovana Sádlová, Tereza Ševčíková, Divya Venkatesh, Čestmı́r Vlček, Petr Volf, Jan Votýpka, Kristína Záhonová, Vyacheslav Yurchenko, Julius Lukeš,
... Here, we present a high-quality genome for Leptomonas pyrrhocoris , which is closely related to the dixenous ... expression data for L. mexicana , L . major and Leptomonas seymouri , we have identified several additional proteins potentially ...
Tópico(s): Helminth infection and control
2016 - Nature Portfolio | Scientific Reports
Natalya Kraeva, Anzhelika Butenko, Jana Hlaváčová, Alexei Yu. Kostygov, Jitka Myšková, Danyil Grybchuk, Tereza Leštinová, Jan Votýpka, Petr Volf, Fred R. Opperdoes, Pavel Flegontov, Julius Lukeš, Vyacheslav Yurchenko,
... The main opportunistic parasite has been identified as Leptomonas seymouri of the sub-family Leishmaniinae. The molecular ... pathways differentially expressed under these experimental conditions. Moreover, Leptomonas seymouri was found to persist for several days ...
Tópico(s): Parasites and Host Interactions
2015 - Public Library of Science | PLoS Pathogens
Vyacheslav Yurchenko, Jan Votýpka, Martina Tesařová, Helena Klepetková, Natalya Kraeva, Milan Jirků, Julius Lukeš,
... Crithidia otongatchiensis Votýpka et lukeš, 2014 from Ecuador, Leptomonas moramango Votýpka et lukeš, 2014 from Madagascar, and ... genera Leishmania ross, 1903, Crithidia léger, 1902 and Leptomonas Kent, 1880, the fourth species clusters together with the 'collosoma' clade (named after 'Leptomonas' collosoma Wallace, clark, Dyer et collins, 1960).Here ...
Tópico(s): Insect symbiosis and bacterial influences
2014 - Institute of Parasitology of the Czech Academy of Sciences | Folia Parasitologica
Produção Nacional
Revisado por pares
Leandro Ferreira, Norival Kesper, Marta M. G. Teixeira, Márcia Dalastra Laurenti, C. Barbieri, José Ângelo Lauletta Lindoso, Eufrosina Setsu Umezawa,
... The antigens from Crithidia fasciculata, Crithidia luciliae, and Leptomonas seymouri showed 100% cross-reactivity with VL and ... by ELISA, that crude extract of Crithidia and Leptomonas have epitopes similar to L. (L.) chagasi, which ...
Tópico(s): Synthesis and Biological Evaluation
2013 - Elsevier BV | Acta Tropica
Jan Votýpka, Helena Klepetková, Vyacheslav Yurchenko, Aleš Horák, Julius Lukeš, Dmitri Maslov,
... frequently occur in Pyrrhocoris apterus, the host of Leptomonas pyrrhocoris Zotta, 1912, a species that had been ... gene sequences, as well as ultrastructure. In addition, Leptomonas scantii n. sp. with an overlapping host range ...
Tópico(s): Hemiptera Insect Studies
2012 - Elsevier BV | Protist
Vyacheslav Yurchenko, Julius Lukeš, Martina Tesařová, Milan Jirků, Dmitri Maslov,
... them has been provisionally assigned to the genus Leptomonas pending the future revision of this genus. Yet, ... Crithidia species. Thus, the extremely long promastigotes of Leptomonas acus sp. n. and the unique morphological features found in Leptomonas bifurcata sp. n. sharply contrast with their respective ...
Tópico(s): Insect symbiosis and bacterial influences
2007 - Elsevier BV | Protist
Produção Nacional
Revisado por pares
S. A. Podlipaev, Nancy R. Sturm, Ivan Fiala, Octávio Fernandes, Scott J Westenberger, Michel Dollet, David A. Campbell, Julius Lukeš,
... Several isolates, assigned by morphology to different genera ( Leptomonas spp., Blastocrithidia spp.), seem to belong to a ... can infect one insect species, as exemplified by Leptomonas sp. PL and Wallaceina sp. Wsd, which were ... and day. However, since the same species of Leptomonas was obtained from insect hosts belonging to different ...
Tópico(s): Insect symbiosis and bacterial influences
2004 - Wiley | Journal of Eukaryotic Microbiology
Hua Luo, Gwen Gilinger, Devi Mukherjee, Vivian Bellofatto,
... of the three promoter elements in the trypanosomatid Leptomonas seymouri. They represent the first trypanosome transcription factors ... of the three promoter elements in the trypanosomatid Leptomonas seymouri. They represent the first trypanosome transcription factors ... Scopus (42) Google Scholar). In the simple trypanosomatid Leptomonas seymouri, a 95-bp region upstream of the ...
Tópico(s): CRISPR and Genetic Engineering
1999 - Elsevier BV | Journal of Biological Chemistry
David Molyneux, S. L. Croft, D. R. Lavin,
Summary The host-parasite relationships of Leptomonas ctenocephali from Ctenocephalides canis and Leptomonas sp. from Orchopeas h. howardi and Palaeopsylla m. minor are described. The latter two species of ...
Tópico(s): Insect and Pesticide Research
1981 - Taylor & Francis | Journal of Natural History
G. Laugé, Richard S. Nishioka,
... Oncopeltus fasciatus was found to be infected by Leptomonas oncopelti. The flagellates form a carpet attached to ... the overlying cuticular intima shows endocuticular canals. The Leptomonas are attached by hemidesmosomes, located most often at ...
Tópico(s): Study of Mite Species
1977 - Wiley | Journal of Morphology