Limpar
1.026 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Jornais Acesso aberto

Jon Ashworth, Richard Beeston and George Brock, Norman Rayner, Graham Chainey, C. B. Bunyan, Campaigns Director, Christopher Warman, Property Correspondent, Patricia Davies, Malcolm Hill, Philip Barron, S. W. Peck, Paul Bompard, Gordon Allan, Sheila Gunn, Political Correspondent, Sally Holloway, Harvey Elliott, C. J. Tyerman, Richard Whitfield, Chairman, Angela MacKay, Philip Howard, Jeremy Kingston, James Bone, Melinda Wittstock, Media Correspondent, Carol Leonard, Wolfgang Münchau, European Business Correspondent, Bill Hayden, Richard Streeton, Stuart Jones Football Correspondent, Neil Bennett, Banking Correspondent, Simon Wilde, Joe Joseph, Martin Fletcher, Brenda Hancock, Bryan Stiles, T. Vafiades (Director), Kavin Eason, Anatole Kaletsky and Ross Tieman, Peter Davenport, Norman Hammond, Archaeology Correspondent, Susan Sturrock, Peter Ball, Louise Taylor, Bill Hagerty, Editor, John Hart, Michael Clark, Philip Robinson, John Young, Tim Hampson (Editor), Richard Lockwood, Geraldine Johnson, Kate Muir, Quentin Cowdry Home Affairs Correspondent, Simon Tait, Roger K. Bingham, Gavin Bell, Douglas Broom Local Government Correspondent, Michael Theodoulou, Janet Daley, Martin Hoyle, Melinda Wittstock Media Correspondent, David Miller, Robin Oakley Political Editor, Barry Millington, Kerry Gill, Jonathan Prynn, Simon Tait Arts Correspondent, John Russell Taylor, Raymond Keene, Chess Correspondent, Alix Ramsay, Paul Griffiths, Peter Bryan, Jonathan Braude, Richard Evans, Jill Sherman, Ian Murray and Robert Seely, Barry Pickthall, John O'leary, Higher Education Correspondent, David Hands Rugby Correspondent, Michael Dynes, Transport Correspondent, Jamie Dettmer, Jack Crossley, John Goodbody, Ross Tieman Industrial Correspondent, James Pringle, Craig Lord, Graham Searjeant, Financial Editor, Mitchell Plattis, Golf Correspondent, John Shaw, Thomson Prentice, Medical Correspondent, Alan Lee Cricket Correspondent, Richard Beeston, Barry Wood, Andrew Lycett, David Sinclair, Melinda Wittstock, William Cash, Michael Horsnell, Alan Coren, Benedict Nightingale, Derek Harris, Quentin Cowdry, Home Affairs Correspondent, Maurice Wood, Chairman, Lulu Yu, James Lancelot, Geoffrey Sykes (Artistic Director), Harvey Elliott Air Correspondent, Matthew Bond, Colin Campbell, Alan Hamilton and Ian Murray, David Watts Diplomatic Correspondent, Mary Dejevsky,

... the mind of a serial killer As Donald Leroy Evans confesses to 60 murders, William Cash describes ... Philip Knowles Church news Don shoots down Robin Hood legend Roland Michener John Monroe Buttresses support a ...

1991 - Gale Group | TDA

Revisão Revisado por pares

Leroy Hood, Lee Rowen, Ben F. Koop,

... Cell Receptor Loci: Genomics, Evolution, Diversity, and Serendipitya LEROY HOOD, LEROY HOOD Department of Molecular Biotechnology University of Washington, FJ- ... 3S1, CanadaSearch for more papers by this author LEROY HOOD, LEROY HOOD Department of Molecular Biotechnology University of Washington, FJ- ...

Tópico(s): RNA and protein synthesis mechanisms

1995 - Wiley | Annals of the New York Academy of Sciences

Artigo Revisado por pares

Leroy Hood, Michael D. Waterfield, James E. Morris, Charles W. Todd,

... LIGHT CHAIN STRUCTURE AND THEORIES OF ANTIBODY DIVERSITY * Leroy Hood, Leroy Hood Division of Biology, California Institute of Technology Pasadena, ... Calif. 91010Search for more papers by this author Leroy Hood, Leroy Hood Division of Biology, California Institute of Technology Pasadena, ...

Tópico(s): Free Radicals and Antioxidants

1971 - Wiley | Annals of the New York Academy of Sciences

Jornais Acesso aberto

Malcolm Brown, Caroline St John-Brooks Education Editor, Rio de Janeiro, Arthur Smith, Jane Langdon-Davies, Richard Ellis, John Jay City Editor, John Davison, Rob Hughes, John Peter, John Child, Eric Dymock, Arthur Marwick Professor, Diana McLellan, Sarah Miller, Christopher Smallwood Economics Editor, Alvin Rakoff President, John Jay, J Pettifer Chairman, Mrs Moira Mulvany, Danby Bloch, Roger Beardwood, Neville Hodgkinson Medical Correspondent, Graham Rose, Gillian Half, Alistair Scott, Joan Greenbalgh, Sally Payne, Ian Williams Business Correspondent, Stephen Milligan, John O'Byrne, Jason Tomas, Cal McCrystal, Mark Hosenball, Patricia Hewitt, Edward Welsh, Carol Rumens, Carol Sarler, Caroline St John-Brooks, Richard Eaton, John Westwell, Neville Hodgkinson, Patrick Stoddart, Susan Marling, Kevin Mitchell, Robert Sandall, Iain Johnstone, Alex Sutherland, Laura Donohue, David Brierley, Irwin Stelzer, Gustav Mahler, Peter Godwin, Robert Hewison, Ivan Fallon, Graham Ogilvie, J Dole Controller & Chief, David Dougill, Mrs M Kirkby, Mark Ottaway, John Mortimer, Mick Brown, Joe Irving, Mark Blacklock, Cliff Temple, Christian Lacroix, Sally Vincent, Wendy Cope, Jihan Ei Tahri, Stan Hibbert Assistant General Secretary, Drew, Justine Picardie, Vincent Whitcombe, Russell Harty, Susan Crosland, Viscount Caldecote, Peter Kemp, Norman Harris, David Connett, Geoff Whitten, Michael Jones, Peter L Boulton, John Cassidy, Sue Mott, Phillips, Bernard Cafferty, Brian Moynahan, Walter Merricks, James Tucker, Amit Roy, Michael Heseltine, Paul Taylor, Conor Cruise O'Brien, Malcolm Smith, Robert Cockburn, Boris Schapiro, Harry Pugh, Ian Hickton, David Hughes, Austin MacCurtain, Mazher Mahmood, Nicolas Freeling, Elizabeth Grice, David Lawrenson, John Hopkins, Keith Orrell, Askold Krushelnycky, Martin Jacques, Patricia Stuart, Liz Fremantle, Judi Bevan, Alan Garner, Joseph Sheehy, Brian Walden, Graham Walker, Eric Marsden, Edwin Riddell, Gill Charlton, Gareth David, Brian Reading, George May, Patrick Woprthington, Anthony Denselom, Bryan Silcock, Jean McGlone, Stephen Pile, Paul Brown, Margaret Prosser, Patricia Wilson, R Tilmouth, Marie Colvin, David Blake, Diana Wright, Christopher Smallwood, Los Angeles, Ellen Donaldson, Stephen Jones, Michel Syrett, Desmond Shawe-Taylor, Brian Deer, Richard Palmer, Raymond Godfrey, Keith Wheatley, Trevor Webster, Patrick Rowley, Dilys Powell, Lyndsay Smith, Andrew Hogg, Brough Scott, Gavin Laird, Charlotte Du Cann, Alison Beckett, Tony Rocca, Caroline McGhie, Clive Everton, Richard Woods, Nicholas Bethell, Louise Branson, Christopher Thomas, Lucia Annunziata, John England, Maurice Chittenden, Max Prangnell, Ian Dunning, Dudley Doust, Felix Aprahamian, Iola Smith, P. F. A. Denman, Michael Haag, David Hughes Political Correspondent, Brian MacArthur, Professor John Radford, Gitta Sereny, Michael Jones Political Editor, Elizabeth Templeton, H A R, John Harrison, Matthew Parris, Malcolm Hart, Terence Lidstone, Steve Tongue, Philip Beresford, Nicholas Kochan, Richard Burnell, Charles Oulton, David Byrne, Brian Glanville, John Carey, Edward Pearce, David Sinclair, Simon Jenkins, Godfrey Golzen, P Murphy, Patricia Mowbray, Rosemary Fong, Sheila Scott, W Bates Director, Jonathan Millar, Barrie Heads, John Cole, Valerie Grove, Marina Vaizey, Alexander MacLeod, Margaret Park, Phillip Knightley, Tony Hetherington, Peter Roebuck, Richard Nixon, Joanna Simon, John Hallows, Paul Gogarty, Deirdre McQuillan, Leslie Geddes-Brown, Georgina Howell, Wendy Craig,

... England Squad Football Results Clough's birthday miss Leroy's the boy Eight is great First salvo ... Bricks on new course Business Extra Henderson Robin Hood Centre plc Rovaspan Modular Buildings Plants learn to ...

1988 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Cecilie Boysen, Melvin I. Simon, Leroy Hood,

... Melvin I. SimonCalifornia Institute of Technology, Pasadena, CA & Leroy Hood*Address correspondence to Leroy Hood, Department of Molecular Biotechnology 357730, University of Washington, ...

Tópico(s): Genomics and Phylogenetic Studies

1997 - Future Science Ltd | BioTechniques

Editorial Acesso aberto Revisado por pares

Charles Auffray, Leroy Hood,

... personalized and participatory (P4) medicine. Edited by Prof. Leroy Hood and Prof. Charles Auffray. During the past decades, ... Institute for Systems Biology & Medicine, Lyon, France Prof. Leroy Hood, Institute for Systems Biology, Seattle, WA, USA

Tópico(s): Bioinformatics and Genomic Networks

2012 - Wiley | Biotechnology Journal

Jornais Acesso aberto

Gráinne Gilmore, Andrew Robson, Giles Smith, Gabriele Marcotti, Alexi Mostrous, Andrew Billen, Charles Mosley, Amy Fallon, Phill Jupitus, Matt Spence, Frances Gibb Legal Editor, Amanda Ursell, Simon Barnes, Peter Lansley, Paul Hoggart, Mark Souster, David Rose, Dr Emily Finch, Ivo Tennant, Philip Howard, Vivien Noakes, Christine Seib, Catherine Bruton, Moritz Volz, Clive Davis, Gabrielle Starkey, Patrick Kidd, Will Pavia, Sam Marlowe, James Hider, Geoff Brown, Martin Samuel Chief Football Correspondent, Robin Pagnamenta, Fiona Hamilton London Correspondent, Pat Gibson, Rob Crilly, Donald Hutera, Siobhan Kennedy, Sir Tom McKillop, Deborah Haynes, Andy Heath, Dominic Walsh, Dan Sabbagh Media Editor, Sir Trevor Brooking, Melanie Reid, Peter Stiff, Daniel Finkelstein, Michael Harvey, Dan Sabbagh, John Drew, Libby Purves, Richard Ford Home Correspondent, Alan Hamilton, Ray Winstone, Anatole Kaletsky, Stephen Claypole, Rhys Blakely, David Hands, John Dresner, Stefanie Marsh, Lilly Peel, Edward Gorman, Richard Hobson Deputy Cricket Correspondent, Richard Simmons Chief executive, Gary Duncan Economics Editor, Oliver Kay, Sarah Vine, Mark Henderson Science Editor, Rick Broadbent, Tom Baldwin, James Rossiter, Pete Paphides, Sandy Milroy, Camila Batmanghelidjh, Rob Wright, Geoffrey Dean, John Hopkins Golf Correspondent, Neil Harman Tennis Correspondent, Professor Desmond Tobin, Martin Samuel, Tim Mickleburgh, Raymond Keene, Adam Sage, Tomás Munita, Lewis Smith, Matthew Pryor, Matt Hughes, Kaveh Solhekol, Mike Drake, Nigel Hawkes, Peta Bee, Chris Campling, Cathy Harris, Anthony Messenger, Lindsey Bareham, Francis Elliott Deputy Political Editor, Stan Collymore, Peter Dixon, Lucy Powell, David Hands Rugby Correspondent, Tony Cascarino, Tom Dart, Julian Muscat, Paul Simons, Guy Legge, William Rees-Mogg, Jonathan Clayton, Philip Webster Political Editor, Celia Hanks, Steve Hawkes, Thomas Catán, Dominic Maxwell, Brendon Batson, Caitlin Moran, Michael Austin, Michael Gove, Philip Webster, Paul Hayes, David Sinclair, Bojan Pancevski, Christopher Irvine, Lisa Verrico, Mark Baldwin, Frank Clark, Veronica Schmidt, Louise Cohen, Brian Logan, Rick Broadbent Athletics Correspondent, Leroy Rosenior, Stephen Dalton, Beth Black, David Escott, Richard Morrison, Alyson Rudd, Gordon Brown, Olav Bjortomt, Mike Atherton Chief Cricket Correspondent, Brian Clarke Fishing Correspondent, Miles Costello, Oliver Fisher, Carolyn Asome Deputy Fashion Editor, Richard Ford, Philip Pank, Rebecca Goldsmith,

... be part of drug rehabilitation Knock down Robin Hood Gardens Timesonline Name and shame Keep it up ...

2008 - Gale Group | TDA

Artigo

Leroy Hood,

... Biology and the Coming of “Big” ScienceLeroy Hood,Leroy Hood,Search for more papers by this authorPublished Online: ... Information© 2011 by GEN PublishingTo cite this article:Leroy Hood,.Biological Complexity Under Attack.Genetic Engineering & Biotechnology News. ...

Tópico(s): Bioinformatics and Genomic Networks

2011 - Mary Ann Liebert, Inc. | Genetic Engineering & Biotechnology News

Jornais Acesso aberto

John Huxley, Barbara Hall, Richard Ellis, James Dairymple, John Davison, Helen Davidson, Philip Norman, Sean O'Brien, David Grubb, Rob Hughes, John Peter, Andrew Grice Political Correspondent, Susan Hill, Mark Reason, Jonathan Miller, Eric Dymock, Lesley White, Fiona Walsh, Susan d'Arcy, Andrew Hogg Middle East Correspondent, Geraldine Bedell, Jeff Rendall, Jan McGirk, Nick Rufford, Isabelle Anscombe, Graham Rose, Leslie Hill, Norman Howell, David Smith, Arthur Appleton, Bernard Knowles, Barbara Amlel, John Pearson, Geordie Greig, Tony Allen-Mills, Susan Marling, Robert Sandall, Don Sieget, Anthony Sattin, Iain Johnstone, John Aspinall, Ivan Fallon, Deryk Brown, Elisabeth Beresford, Jeremy Young, Joanna Rahim, Tania Alexander, Hugh Canning, Margarette Driscoll, David Rocastle, Michael De Larrabeiti, John Prescott, Renée Short, lan Birrell, Mervyn LeRoy, Christie's Davidge, Taki Theodoracopulos, Robert Harris, Michel Montignac, Caroline Lees, Peter Millar, Flona Walsh, George Perry, Sue Mott, John Cassidy, Mark Skipworth, Philip Robinson, Bernard Cafferty, Fiona Walsh Deputy City Editor, Susan Tighe, Paul Donovan, Anthony Rogers, Jeff Randall, John Wardroper, M Walker, Brian Moynahar, Paul Driver, James Adams, Boris Schapiro, Margaret Dibben, David Hughes, David Leppard, Tim Rayment, Brian Jackman, John Walker, John Stalker, David Lawrenson, Janet Holmes, Rosemary Stark, Charles Hymas Education Correspondent, Christopher Lloyd, Malcolm Rifkind, Dennis Appleyard, Sally Ogle Davis, Sian Roberts, Peter Martin, John Karter, Malcolm Winton, Marina Cantacuzino, Marie Colvin, Craig Brown, Diana Wright, Loyd Grossman, Stephen Jones, Richard Palmer, Andrew Grice, Martin Searby, Ian Birrell, Ludovlc Kennedy, Moshe Kabtan, Bryan Appleyard, Chris Jones, Richard Woods, Clive Everton, Garth Alexander, Alistair Scolt, Peter Johnson, Rt Hon Julian Amery, Mark McCormack, Maurice Chittenden, Mitchell Symons, John Walsh, David Hughes Chief Political Correspondent, Brian MacArthur, Andrew Yales, Craig Lord, Rebecca Fowler, Michael Jones Political Editor, Andrew Yates, David Hunn, James Blitz, Daniela Soave, Clare Medwin, Geoffrey Hobbs, Mihir Bose, Michael Austin, Lesley Douglas, Brian Glanville, Stan Levenson, C Whitham, Aileean Ballantyne, Rajeev Syal, Oliver North, Norman Macrae, Chris Dighton, Perry Perrick, Tony Moss, Geordie Grieig, Bookwatch, Andrew Lorenz, Liam Clarke, lan Burrell, Ray Rowland, Doug Houston, Ronald Neame, Keith Waterhouse, Marina Vaizey, Chris Lightbown, Andrew Davidson, Paula Reed, Geoffrey Robertson, John Kohut, David Smith Economics Editor, Roy Baker, Tony Hetherington, Dr L Stather-Dunn, Peter Roebuck, Joanna Simon, Robin Hood, Sotheby's Llewellyn,

Wealthy landowners get handouts for doing nothing Insight Homosexual laws thrown into turmoil Move to lower consenting age to 16 Gloom for Labour as Tories ...

1991 - Gale Group | Sunday Times HA GDA

Revisão Revisado por pares

Carol Readhead, NAOKI TAKASASHI, H. David Shine, Raul A. Saavedra, Richard L. Sidman, L HOOD,

... 02115Search for more papers by this authorLEROY HOOD, LEROY HOOD California Institute of Technology Pasadena, California 91125Search for ... 02115Search for more papers by this authorLEROY HOOD, LEROY HOOD California Institute of Technology Pasadena, California 91125Search for ...

Tópico(s): Axon Guidance and Neuronal Signaling

1990 - Wiley | Annals of the New York Academy of Sciences

Artigo Acesso aberto Revisado por pares

Daehee Hwang, Inyoul Y. Lee, Hyuntae Yoo, Nils Gehlenborg, Ji‐Hoon Cho, Brianne Petritis, David Baxter, Rose Pitstick, Rebecca Young, Doug Spicer, Nathan D. Price, John G. Hohmann, Stephen J. DeArmond, George A. Carlson, Leroy Hood,

... USA Search for more papers by this author Leroy E Hood Corresponding Author Leroy E Hood Institute for Systems Biology, Seattle, WA, USA Search ... USA Search for more papers by this author Leroy E Hood Corresponding Author Leroy E Hood Institute for Systems Biology, Seattle, WA, USA Search ... Stephen J DeArmond6, George A Carlson 4 and Leroy E Hood 1 1Institute for Systems Biology, Seattle, WA, USA ...

Tópico(s): Neurological diseases and metabolism

2009 - Springer Nature | Molecular Systems Biology

Artigo Acesso aberto Revisado por pares

Seth A. Ament, Jocelynn R. Pearl, Jeffrey P. Cantle, Robert M. Bragg, Peter J. Skene, Sydney R. Coffey, Dani E. Bergey, Vanessa C. Wheeler, Marcy E. MacDonald, Nitin S. Baliga, Jim Rosinski, Leroy Hood, Jeffrey B. Carroll, Nathan D. Price,

... USA Search for more papers by this author Leroy E Hood Leroy E Hood Institute for Systems Biology, Seattle, WA, USA Search ... USA Search for more papers by this author Leroy E Hood Leroy E Hood Institute for Systems Biology, Seattle, WA, USA Search ...

Tópico(s): Microbial Metabolic Engineering and Bioproduction

2018 - Springer Nature | Molecular Systems Biology

Artigo Acesso aberto Revisado por pares

Seth A. Ament, Szabolcs Szelinger, Gustavo Glusman, J. R. Ashworth, Liping Hou, Nirmala Akula, Tatyana Shekhtman, Judith A. Badner, Mary E. Brunkow, Denise E. Mauldin, Anna-Barbara Stittrich, Katherine Rouleau, Sevilla D. Detera‐Wadleigh, John I. Nürnberger, Howard J. Edenberg, Elliot S. Gershon, Nicholas J. Schork, Nathan D. Price, Richard Gelinas, Leroy Hood, David W. Craig, Francis J. McMahon, John R. Kelsoe, Jared C. Roach, John R. Kelsoe, Tiffany A. Greenwood, Caroline M. Nievergelt, Paul D. Shilling, Tatyana Shekhtman, Jared C. Roach, Seth A. Ament, Leroy Hood, John I. Nürnberger, Howard J. Edenberg, Tatiana Foroud, Daniel L. Koller, Elliot S. Gershon, Judith A. Badner, Chunyu Liu, William A. Scheftner, William Lawson, William Coryell, James B. Potash, John P. Rice, William Byerley, Francis J. McMahon, Liping Hou, Wade H. Berrettini, Peter P. Zandi, Melvin G. McInnis, David W. Craig, Szabolcs Szelinger, Thomas G. Schulze, Nicholas J. Schork, Danjuma Quarless,

Significance Bipolar disorder (BD) is a common, severe, and recurrent psychiatric disorder with no known cure and substantial morbidity and mortality. Heritable causes contribute up to 80% of the lifetime risk for BD. Common genetic variation explains ∼25% of this heritable risk. Rare genetic variants may explain additional risk. We identified contributions of rare variants to BD by sequencing the genomes of 200 individuals from 41 families with BD. The two main findings of this study were as follows: ...

Tópico(s): Genomics and Rare Diseases

2015 - National Academy of Sciences | Proceedings of the National Academy of Sciences

Artigo Acesso aberto

Biaoyang Lin, Hwahyung Lee, Jae-Geun Yoon, Anup Madan, Elizabeth A. Wayner, Sanja Tonning, Parvinder Hothi, Brett Schroeder, Ilya V. Ulasov, Gregory Foltz, Leroy Hood, Charles Cobbs,

... Schroeder 4 , Ilya Ulasov 4 , Gregory Foltz 4 , Leroy Hood 5 , Charles Cobbs 4 1 Cancer Institute (Key ...

Tópico(s): Cancer-related molecular mechanisms research

2015 - Impact Journals LLC | Oncotarget

Artigo

Leroy Hood, Nathan D. Price,

... 3May 2014 InformationCopyright © GEN PublishingTo cite this article:Leroy Hood and Nathan D. Price.Promoting Wellness & Demystifying Disease: ...

Tópico(s): Health, Environment, Cognitive Aging

2014 - Mary Ann Liebert, Inc. | Clinical OMICs

Artigo Acesso aberto Revisado por pares

Adriano Henney,

... resounding no” (Anon, 2007). In the intervening period, Leroy Hood and Roger Perlmutter had already predicted that the ... to describe systems biology; however, one definition from Leroy Hood lays the foundations for the others: “systems biology ...

Tópico(s): Lung Cancer Treatments and Mutations

2009 - Springer Nature | EMBO Reports

Artigo Revisado por pares

Neil Stahl, Michael A. Baldwin, David B. Teplow, Leroy Hood, Bradford W. Gibson, Alma L. Burlingame, Stanley B. Prusiner,

... sequencingNeil Stahl, Michael A. Baldwin, David B. Teplow, Leroy Hood, Bradford W. Gibson, Alma L. Burlingame, and Stanley ...

Tópico(s): RNA regulation and disease

1993 - American Chemical Society | Biochemistry

Artigo Revisado por pares

Ruedi H. Aebersold, Gary D. Pipes, Heinz Nika, Leroy Hood, Stephen B. H. Kent,

... gelsRuedi H. Aebersold, Gary D. Pipes, Heinz Nika, Leroy E. Hood, and Stephen B. H. KentCite this: Biochemistry 1988, ...

Tópico(s): Advanced biosensing and bioanalysis techniques

1988 - American Chemical Society | Biochemistry

Editorial Acesso aberto Revisado por pares

Ho Jeong Kwon, Thomas E. Fehniger, György Marko‐Varga,

... complemented by the 4P medicine concept, introduced by Leroy Hood, (Institute for Systems Biology in Seattle), where proteomic ... Mill. President Obama's Precision Medicine Program with Leroy Hood has paved the way for the ability to ...

Tópico(s): Colorectal Cancer Treatments and Studies

2016 - Springer Science+Business Media | Clinical and Translational Medicine

Artigo Revisado por pares

John Skår, Peter V. Coveney,

Dr Leroy Hood, the President and Director of the Institute for Systems Biology in Seattle, WA, USA, also spoke at ...

Tópico(s): Sustainability and Ecological Systems Analysis

2003 - Royal Society | Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences

Artigo Acesso aberto Revisado por pares

Elwyn Loh, Brian L. Black, Roy Riblet, Martin Weigert, J.M. Hood, Leroy Hood,

Structural and functional analyses of myeloma immunoglobulins from inbred BALB/c mice and humans have provided important insights into the structure of the antibody molecule and the expression and evolution of antibody genes. One important question concerning these analyses is whether the myeloma process selects, in a nonrandom manner, the lymphocytes to be transformed. The availability of myeloma tumors in a second inbred strain of mouse, NZB, permits us to approach this question. In this respect. ...

Tópico(s): Multiple Myeloma Research and Treatments

1979 - National Academy of Sciences | Proceedings of the National Academy of Sciences

Artigo Acesso aberto Revisado por pares

Ronald A. Barry, Stephen B. H. Kent, Michael P. McKinley, R. Meyer, S. J. DeArmond, L Hood, S. B. Prusiner,

... this author on: Oxford Academic PubMed Google Scholar Leroy E. Hood, Leroy E. Hood From the Departments of Neurology, Biochemistry and Biophysics, ...

Tópico(s): Neurological diseases and metabolism

1986 - Oxford University Press | The Journal of Infectious Diseases

Artigo Revisado por pares

Jens Nielsen,

... called P4 medicines. This concept, introduced earlier by Leroy Hood and described at the Symposium, predicts that society ...

Tópico(s): Microbial Metabolic Engineering and Bioproduction

2011 - Wiley | Journal of Internal Medicine

Artigo Revisado por pares

Allan I Pack,

Dr. Leroy Hood promotes a paradigm to advance medical care that he calls P4 medicine. The four Ps are: personalized, ...

Tópico(s): Fatty Acid Research and Health

2016 - American Thoracic Society | Annals of the American Thoracic Society

Artigo Revisado por pares

Shizhen Qin, Yong Zhou, Li Gray, Ulrike Kusebauch, Laurence McEvoy, Daniel J. Antoine, Lucy Hampson, Kevin B. Park, David Campbell, Juan Caballero-Pérez, Gustavo Glusman, Xiaowei Yan, Taek-Kyun Kim, Yue Yuan, Kai Wang, Lee Rowen, Robert L. Moritz, Gilbert S. Omenn, Munir Pirmohamed, Leroy Hood,

Organ-enriched blood proteins, those produced primarily in one organ and secreted or exported to the blood, potentially afford a powerful and specific approach to assessing diseases in their cognate organs. We demonstrate that quantification of organ-enriched proteins in the blood offers a new strategy to find biomarkers for diagnosis and assessment of drug-induced liver injury (and presumably the assessment of other liver diseases). We used selected reaction monitoring (SRM) mass spectrometry to ...

Tópico(s): Pharmacogenetics and Drug Metabolism

2016 - American Chemical Society | Journal of Proteome Research

Artigo Acesso aberto Revisado por pares

Ivo D. Dinov, Ben Heavner, Ming Tang, Gustavo Glusman, Kyle Chard, Mike D’Arcy, Ravi Madduri, Judy Pa, Cathie Spino, Carl Kesselman, Ian Foster, Eric W. Deutsch, Nathan D. Price, John D. Van Horn, Joseph Ames, Kristi Clark, Leroy Hood, Benjamin M. Hampstead, William T. Dauer, Arthur W. Toga,

A unique archive of Big Data on Parkinson's Disease is collected, managed and disseminated by the Parkinson's Progression Markers Initiative (PPMI). The integration of such complex and heterogeneous Big Data from multiple sources offers unparalleled opportunities to study the early stages of prevalent neurodegenerative processes, track their progression and quickly identify the efficacies of alternative treatments. Many previous human and animal studies have examined the relationship of Parkinson' ...

Tópico(s): Gene expression and cancer classification

2016 - Public Library of Science | PLoS ONE

Revisão Revisado por pares

Michael Sagner, Amy McNeil, Pekka Puska, Charles Auffray, Nathan D. Price, Leroy Hood, Carl J. Lavie, Ze‐Guang Han, Chen Zhu, Samir K. Brahmachari, Bruce S. McEwen, Marcelo B. Soares, Rudi Balling, Elissa S. Epel, Ross Arena,

Chronic diseases (i.e., noncommunicable diseases), mainly cardiovascular disease, cancer, respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and diminished quality of life on the planet. Moreover, these diseases are also a major financial burden worldwide, significantly impacting the economy of many countries. Healthcare systems and medicine have progressively improved upon the ability to address infectious diseases and react to adverse health events through ...

Tópico(s): Health, Environment, Cognitive Aging

2016 - Elsevier BV | Progress in Cardiovascular Diseases