Aleksandar Medović, Aleksandar Mikić, Branko Ćupina, Živko Jovanović, Svetlana Radović, Aleksandra Nikolić, Nemanja Stanisavljević,
... sample from the hill fort settlement Hissar near Leskovac represents a unique example in Bronze / Iron Age ... confirms a long tradition of the city of Leskovac region as a pulse crop production centre in ...
Tópico(s): Ancient Mediterranean Archaeology and History
2011 - Institute of field and vegetable crops, Novi Sad | Ratarstvo i povrtarstvo
Vladimir Leskovac, Anthony D. Theoharides,
... rat liver microsomes, presented in the preceding communication (Leskovac and Theoharides, 1991), we were able to postulate ...
Tópico(s): Computational Drug Discovery Methods
1991 - Elsevier BV | Comparative Biochemistry and Physiology Part C Comparative Pharmacology
Živko Jovanović, Nemanja Stanisavljević, Aleksandra Nikolić, Aleksandar Medović, Aleksandar Mikić, Svetlana Radović, Vuk Djordjević,
... vetch seeds from the site of Hissar near Leskovac, South Serbia, using two different DNA extraction procedures. ...
Tópico(s): Historical and Archaeological Studies
2011 - Institute of field and vegetable crops, Novi Sad | Ratarstvo i povrtarstvo
Aleksandra Đjukić, Milena Vukmirović, Srdjan Stankovic,
... open public space of the main square in Leskovac. The analysis covers the present state, two rewarded ...
Tópico(s): Building Energy and Comfort Optimization
2015 - Elsevier BV | Energy and Buildings
Tatjana Popović, Žarko Ivanović, Maja Ignjatov,
... greenhouse tomato (Solanum lycopersicum L.) was observed in Leskovac, in the south of Serbia. Tomato production in ... the dominant species causing pith necrosis in the Leskovac region where tomato is traditionally grown in greenhouses. ...
Tópico(s): Plant Pathogens and Fungal Diseases
2015 - American Phytopathological Society | Plant Disease
Slaviša Trajković, Srdjan Kolaković, Marija Ignjatović,
... users of waters) about the irrigation of the Leskovac field. The public opinion survey that was conducted in the Leskovac municipality shows that a great majority of farmers ...
Tópico(s): Environmental Science and Water Management
2005 - | Facta universitatis - series Architecture and Civil Engineering
Vladimir Leskovac, Svetlana Trivić,
... of aryl nitroso compounds by 1,4-dihydronicotinamidesVladimir Leskovac and S. TrivicCite this: J. Org. Chem. 1988, ...
Tópico(s): Chemical Synthesis and Reactions
1988 - American Chemical Society | The Journal of Organic Chemistry
Radmila Pivić, Zoran Dinić, Aleksandar Stanojković, Jelena Maksimović, Dragana Jošić, Aleksandra Stanojković-Sebić,
... Eutric cambisol along the E75 route section Belgrade-Leskovac, were examined in order to assess the health ...
Tópico(s): Heavy Metals in Plants
2017 - Faculty of Agronomy in Čačak | Biotechnology in Animal Husbandry
Vladimir Leskovac, Draginja Peričin, Svetlana Trivić,
... preparations tested in this, and our earlier work (Leskovac & Pavkov-Peričin, 1975; Leskovac et al., 1976), bind approx. 2 molecules of ...
Tópico(s): Amino Acid Enzymes and Metabolism
1978 - Elsevier BV | International Journal of Biochemistry
Vladimir Leskovac, Gerhard Pfleiderer,
Article Evidence for a Methionyl Residue in the Active Site of the Cytoplasmic Malate Dehydrogenase from Pig Heart was published on January 1, 1969 in the journal Biological Chemistry (volume 350, issue 1).
Tópico(s): Diet, Metabolism, and Disease
1969 - De Gruyter | Hoppe-Seyler´s Zeitschrift für physiologische Chemie
Milan Stanulović, V. Jeremić, Vladimir Leskovac, Sterling Chaykin,
The only enzyme demonstrated so far to catalyze the formation of 4-pyridoxic acid, the final excretory product of vitamin B(6), was aldehyde oxidase. In this paper we have presented an evidence that another enzyme, NAD^+-dependent aldehyde dehydrogenase, is capable of catalyzing this reaction. Rat mutants with high, low and no aldehyde oxidase activity excrete the same amount of isotope after a single injection of ³H-pyridoxol in a 12-day experiment; 4-pyridoxic acid is also present in the urine ...
Tópico(s): Diabetes and associated disorders
1976 - Karger Publishers | Enzyme
Vladimir Leskovac, Svetlana Trivić, M Latkovska,
1. Yeast alcohol dehydrogenase (EC 1.1.1.1) is inhibited in the presence of 1,10-phenanthroline. 2. A conformational change in the enzyme's structure is induced by 1,10-phenanthroline, and is abolished in the presence of NADH. 1,10-Phenanthroline binds to the enzyme competitively with respect to NADH, with a stoicheiometry of 2 mol of 1,10-phenanthroline/144000g of enzyme. 3. 1,10-Phenanthroline induces a time-dependent dissociation of Zn2+ from the enzyme, which is in correlation with its inhibitions. ...
Tópico(s): Electrochemical sensors and biosensors
1976 - Portland Press | Biochemical Journal
Vladimir Leskovac, D. Pavkov-Peričin,
1. Yeast alcohol dehydrogenase (EC 1.1.1.1) is inhibited by stoicheiometric concentrations of diethyl pyrocarbonate. The inhibition is due to the acylation of a single histidine residue/monomer (mol.wt. 36000). 2. Alcohol dehydrogenase is also inhibited by stoicheiometric amounts of 5,5′-dithiobis-(2-nitrobenzoate), owing to the modification of a single cysteine residue/monomer. 3. Native alcohol dehydrogenase binds two molecules of reduced coenzyme/molecule of enzyme (mol.wt. 144000). 4. Modification ...
Tópico(s): Enzyme Catalysis and Immobilization
1975 - Portland Press | Biochemical Journal
... 1139/m78-109 CASPubMedWeb of Science®Google Scholar Leskovac V, Popovic M (1980): Mechanism of reduction of ...
Tópico(s): Cancer therapeutics and mechanisms
1983 - Wiley | Environmental Mutagenesis
Vladimir Leskovac, Jasmina Svirčević, Svetlana Trivić, M. Popović, Mirjana Radulović,
1. A systematic kinetic investigation of the reduction of aryl-nitroso compounds by pyridine and flavin coenzymes and their analogs, in enzymatic and nonenzymatic systems, has been reported. 2. Two main groups of nitroso compounds have been investigated, representatives nitroso-benzene and 1-nitroso-2-naphthol; in all enzymatic and nonenzymatic systems, the former was always reduced to phenyl-hydroxyl-amine and the latter to 1-amino-2-naphthol. 3. Pyridine compounds included NADH, APAD-4H2 and DBNA- ...
Tópico(s): Chemical Reaction Mechanisms
1989 - Elsevier BV | International Journal of Biochemistry
Mirjana B. Čolović, Danijela Krstić, Sandra Petrović, Andreja Leskovac, Gordana Joksiċ, Jasmina Savić, Mladen Franko, Polonca Trebše, Vesna Vasić,
The toxic effects of diazinon and its irradiated solutions were investigated using cultivated human blood cells (lymphocytes and erythrocytes) and skin fibroblasts. Ultra Performance Liquid Chromatography (UPLC)-UV/VIS system was used to monitor the disappearance of starting diazinon during 115-min photodegradation and formation of its by-products (diazoxon and 2-isopropyl-6-methyl-4-pyrimidinol (IMP)) as a function of time. Dose-dependent AChE and Na(+)/K(+)-ATPase inhibition by diazinon was obtained ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2009 - Elsevier BV | Toxicology Letters
Aleksandra Bočarov‐Stančić, J. Lević, Slavica Stankоvić, Mladen Stanisic, Sasa Bilek,
... DON), was isolated from maize kernel collected at Leskovac in 1975. Preliminary analysis of fungal potential for ...
Tópico(s): Wheat and Barley Genetics and Pathology
2009 - Matica srpska | Zbornik Matice srpske za prirodne nauke
Jelena Cvetićanin, Gordana Joksiċ, Andreja Leskovac, Sandra Petrović, Ana Valenta Šobot, O. Nešković,
Carbon nanotubes are unique one-dimensional macromolecules with promising applications in biology and medicine. Since their toxicity is still under debate, here we present a study investigating the genotoxic properties of purified single wall carbon nanotubes (SWCNTs), multiwall carbon nanotubes (MWCNTs), and amide functionalized purified SWCNTs on cultured human lymphocytes employing cytokinesis block micronucleus assay and enumeration of γH2AX foci as a measure of double strand breaks (DSBs) of the ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2009 - IOP Publishing | Nanotechnology
Vladimir Leskovac, Anthony D. Theoharides,
1. In this communication, metabolism of the semisynthetic antimalarial drugs of the artemisinin class (beta-arteether, beta-artelinic acid and dihydroartemisinin) in rat liver microsomes, is reported. 2. Dihydroartemisinin was the major early metabolite of arteether (57%) and artelinic acid (80%); in addition, arteether was hydroxylated in the positions 9 alpha- and 2 alpha- of the molecule. 3. Dihydroartemisinin was further metabolized by extensive hydroxylation of its molecule; we were able to identify ...
Tópico(s): Pharmacogenetics and Drug Metabolism
1991 - Elsevier BV | Comparative Biochemistry and Physiology Part C Comparative Pharmacology
Biljana Kaličanin, Nikola Marjanović, Zvonimir Suturović,
... manufacture (Faculty of Technology, Novi Sad and "Elektrouniverzal", Leskovac). The accuracy of the method was confirmed by ...
Tópico(s): Analytical Chemistry and Sensors
2002 - Serbian Chemical Society | Journal of the Serbian Chemical Society
Vladimir Leskovac, S TRIVI, D PERIIN,
This review is a summary of our current knowledge of the structure, function and mechanism of action of the three zinc-containing alcohol dehydrogenases, YADH-1, YADH-2 and YADH-3, in baker's yeast, Saccharomyces cerevisiae. The opening section deals with the substrate specificity of the enzymes, covering the steady-state kinetic data for its most known substrates. In the following sections, the kinetic mechanism for this enzyme is reported, along with the values of all rate constants in the mechanism. ...
Tópico(s): Biofuel production and bioconversion
2002 - Oxford University Press | FEMS Yeast Research
Vera Kovačević, Sanja Lučić, Mirela Leskovac,
Abstract Nanocomposites are expected to exhibit new and improved properties when compared to their microcomposite counterparts. By lowering the particle size to nanodimensions (<100 nm), the special effects in polymer composites appear. In this study we compared the properties of composites filled with micro- and nano-sized calcium carbonate (CaCO3) filler particles in poly (vinyl acetate) (PVAc) matrix. The morphology of the composite was found to be responsible for the composite properties. The filler ...
Tópico(s): biodegradable polymer synthesis and properties
2002 - Taylor & Francis | Journal of Adhesion Science and Technology
Vladimir Leskovac, Svetlana TriviÄ, Draginja PeriÄin,
This review is a summary of our current knowledge of the structure, function and mechanism of action of the three zinc-containing alcohol dehydrogenases, YADH-1, YADH-2 and YADH-3, in baker's yeast, Saccharomyces cerevisiae. The opening section deals with the substrate specificity of the enzymes, covering the steady-state kinetic data for its most known substrates. In the following sections, the kinetic mechanism for this enzyme is reported, along with the values of all rate constants in the mechanism. ...
Tópico(s): Protein Structure and Dynamics
2002 - Oxford University Press | FEMS Yeast Research
Perica Ž. Pešić, Vladimir Banković,
... sclarea L. on the experimental plot of Hisar (Leskovac), through three different phases of herbal development: at ...
Tópico(s): Traditional Chinese Medicine Analysis
2003 - Wiley | Flavour and Fragrance Journal
Vera Kovačević, Domagoj Vrsaljko, Sanja Lučić Blagojević, Mirela Leskovac,
Abstract The interface in particulate filled polymer systems determine to a large extent, the mechanical and morphological properties of composites and polymer blends. The present contribution describes surface free energy measurements and calculations of adhesion parameters at the interface in poly(vinyl acetate) (PVAc) and polyurethane (PU) composites as well as in styrene acrylonitrile/ethylene propylene diene monomer (SAN/EPDM) blends filled with calcium carbonate (CaCO 3 ) nanofillers. The effects ...
Tópico(s): Polymer Science and PVC
2008 - Wiley | Polymer Engineering and Science
Domagoj Vrsaljko, Mirela Leskovac, Sanja Lučić Blagojević, Vera Kovačević,
Abstract Polyurethane (PU) and poly(vinyl acetate) (PVAc) are partially miscible polymers. The aim of this study was to investigate the influence of untreated and surface pretreated calcium carbonate (CaCO 3 ) on the interphase properties of PU/PVAc polymer blends with possible compatibilization effects when the conditions of effective adhesion are achieved. With the aim to modify interface between filler and matrices, CaCO 3 was pretreated by grafting PVAc on the filler surface using 60 Co γ‐ray irradiation ...
Tópico(s): biodegradable polymer synthesis and properties
2008 - Wiley | Polymer Engineering and Science
Domagoj Vrsaljko, Sanja Lučić Blagojević, Mirela Leskovac, Vera Kovačević,
AbstractAbstractIn the present paper, the changes at interface between calcium carbonate (CaCO3) and polyurethane (PU) matrix in correlation to the mechanical and morphological properties were investigated. The effect of the untreated CaCO3 microfillers versus nanofillers and/or selected silane pretreatment of nanofiller surface were followed. Correlation between the calculated adhesion parameters i.e. interfacial free energy, thermodynamic reversible work of adhesion and coefficient of wetting, based ...
Tópico(s): Tribology and Wear Analysis
2008 - Taylor & Francis | Materials Research Innovations
Miodrag Šmelcerović, Dragan Djordjеvic, Mile Novakovič, Mirjana Mizdraković,
... of brown coal in the heating station of Leskovac (Serbia) was used for the treatment of waste ...
Tópico(s): Environmental remediation with nanomaterials
2010 - Serbian Chemical Society | Journal of the Serbian Chemical Society
Andreja Leskovac, Dragana Vujić, Marija Guć‐Šćekić, Sandra Petrović, Ivana Joksić, Predrag Slijepčević, Gordana Joksiċ,
Among patients with bone marrow failure (BMF) syndrome, some are happened to have underlying Fanconi anemia (FA), a genetically heterogeneous disease, which is characterized by progressive pancytopenia and cancer susceptibility. Due to heterogeneous nature of the disease, a single genetic test, as in vitro response to DNA cross-linking agents, usually is not enough to make correct diagnosis. The aim of this study was to evaluate whether measuring repair kinetics of radiation-induced DNA double-strand ...
Tópico(s): Genomics and Chromatin Dynamics
2010 - Tohoku University | The Tohoku Journal of Experimental Medicine
Emi Govorčin Bajsić, Anđela Pustak, Ivan Šmit, Mirela Leskovac,
Abstract Neat thermoplastic polyurethane (TPU), polypropylene (PP), and TPU/PP blends with different weight ratios that were prepared in a twin‐screw extruder were investigated with differential scanning calorimetry and light and scanning electron microscopy. The results confirmed PP matrix to TPU matrix phase inversion in the concentration region between 60/40 and 80/20 TPU/PP blends. The total degree of crystallinity of the blends and the crystallization temperature of PP decreased with increasing ...
Tópico(s): biodegradable polymer synthesis and properties
2010 - Wiley | Journal of Applied Polymer Science