"The booke for a justice of peace" has been erroneously attributed to Sir Anthony Fitzherbert. Cf. NUC pre-1956. Date of publication from Goldsmiths' ...
0000 - Gale Group | The Making of Modern World
Michael A. Bachman, Michele S. Swanson,
... regulator LetA/LetS and is enhanced by the letE locus. Here we demonstrate that letE promotes motility by increasing expression of the flagellin ... sigma factor gene. In addition to promoting motility, letE induces the characteristic shape, pigment, and heat resistance ... phase L. pneumophila. To gain insight into how letE promotes the expression of the transmission phenotype, we ... experiments to discriminate between the following three models: letE mutations are polar on milX; letE encodes a small novel protein; or, by analogy ...
Tópico(s): Bacterial Genetics and Biotechnology
2004 - American Society for Microbiology | Infection and Immunity
H. Du Buysson, M. Raffray, G. Rouy, L. Fairmaire, Félix Angey, Emile Deyrolle,
... Georgei.— Long. 26 À 27 Millim.— Noire, Glabre; Lête Avec Une Ponctuation Assez Espacée Et Grossière, …, Séance ...
1886 - Gale Group | NCCO-STM 1of2
Sandra P. D’Angelo, Jonathan Noujaim, Fiona Thistlethwaite, Albiruni Ryan Abdul Razak, Silvia Stacchiotti, Warren Chow, John B.A.G. Haanen, A. Chalmers, Steven I. Robinson, Brian Andrew Van Tine, Kristen N. Ganjoo, Melissa L. Johnson, Victoria L. Chiou, Thomas Faitg, Mary Woessner, Laura Pearce, Aiman Shalabi, Jean‐Yves Blay, George D. Demetri,
TPS11582 Background: Letetresgene autoleucel (lete-cel; GSK3377794) is an autologous T-cell product using a genetically modified T-cell receptor to target cancer cells expressing ... esophageal squamous cell carcinoma 1 (NY-ESO-1). Lete-cel is currently being investigated alone and in ... 3,4], suggesting these tumors may be prime lete-cel targets. This master protocol design (IGNYTE-ESO; ... and treatment stages in separate substudies, beginning with lete-cel in Substudies 1 and 2 for SS ... Substudy 1 is a single-arm study assessing lete-cel in treatment-naïve patients (pts; ie, anthracycline ...
Tópico(s): Immunotherapy and Immune Responses
2021 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... 2291(pt.) Letter. To Sir D. E. De Lete. Yokohama.
0000 - Gale Group | NCCO AsiaWest
Sandra P. D’Angelo, Andrew Furness, Fiona Thistlethwaite, Melissa Burgess, Richard F. Riedel, John B.A.G. Haanen, Jonathan Noujaim, A. Chalmers, Antonio López‐Pousa, Rashmi Chugh, Lara E. Davis, Édouard Forcade, Mark Agulnik, Dennis Williams, Mary Woessner, Thomas Faitg, Beth Ireland, Michael J. Nathenson, Elliot Norry, Albiruni Ryan Abdul Razak,
2500 Background: Letetresgene autoleucel (lete-cel) is an autologous engineered T cell receptor therapy targeting the NY-ESO-1 cancer testis antigen highly expressed in ... sarcoma (SyS) and myxoid/round cell liposarcoma (MRCLS). Lete-cel pilots showed promising efficacy in patients (pts) ... follow-up. Safety population: pts who had received lete-cel at time of the IA. Pre-defined ... IA, 98 pts were apheresed, 73 pts received lete-cel (safety) and 45 pts were evaluable for ... AEs) were consistent with those previously observed with lete-cel. Most common AEs (all grades) were cytokine ...
Tópico(s): Cardiac tumors and thrombi
2024 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
... that the Ministerial policy in Egypt is "obs lete," because of the defeat of Baker Pasha's ...
1884 - Gale Group | SASII
Alexandra Gyurdieva, Stefan Zajic, Ya-Fang Chang, E. Andrés Houseman, Shan Zhong, Jaegil Kim, Michael J. Nathenson, Thomas Faitg, Mary Woessner, David C. Turner, Aisha Hasan, John Glod, Rosandra N. Kaplan, Sandra P. D’Angelo, Dejka M. Araujo, Warren Chow, Mihaela Druta, George D. Demetri, Brian A. Van Tine, Stephan A. Grupp, Gregg Fine, Ioanna Eleftheriadou,
... receptor specific to NY-ESO-1 (letetresgene autoleucel, lete-cel) show promise in the treatment of metastatic ... with 50% overall response rate. The efficacy of lete-cel treatment in 45 synovial sarcoma patients (NCT01343043) ... post-hoc analysis identifies associations of response to lete-cel with lymphodepleting chemotherapy regimen (LDR), product attributes, ... respectively). Analysis of tumor samples post-treatment illustrates lete-cel infiltration and a decrease in expression of ... we report potential predictive and pharmacodynamic markers of lete-cel response that may inform LDR, cell dose, ...
Tópico(s): Virus-based gene therapy research
2022 - Nature Portfolio | Nature Communications
(Mrs.) A. F. Ledbrook, Ernest Newman, Lloyd's, John S. Steele, W. Davies, Yarborough, Autolycus, S. L., T. P. O'connor M. P., C. T. Taylor, J. R. H., Rebecca West, F. G., E. V. Lucas, (Mrs.) May Belben, James Agate, Frederick Annesley, Frank Adkins, Edmund Gosse, George C. Stead, Geo Nickson, Anna Jeuness Miller, S. Eardley-Wilmot, Bennett Harris, E. P. B., George C. Peachey, Isabel Smith, H. C. Minchin, H. J. Stratton, Geo H. Culshaw, Roland Atkinson, St. Andrews, Birdseye, Comdr A. T. Stewart R. N., Scot, E. G., Brodie Fraser, H. Beal, L. Vanvliet, M. D., W. Eugene Wason, Joseph Cullen, Pandora, H. F., St. John Adcock, (Mrs) Catharine Bodham-Johnson, J. W. Y. Bannard, R. M. L., Roy C. Warden, Ernest Loxley, R. J. Barrett Financial Editor, Harold Cox,
... Y. Craig—The Queen of Rumania—Hommage a Lete "The Town": Men and Intimacies Building Blocked Trade ...
1924 - Gale Group | Sunday Times HA GDA
Sandra P. D’Angelo, Mihaela Druta, Brian Andrew Van Tine, David A. Liebner, Scott M. Schuetze, Michael J. Nathenson, Andrew Holmes, Jimson W. D’Souza, Gurpreet S. Kapoor, Stefan Zajic, Neeta Somaiah,
11500 Background: Lete-cel is an autologous T-cell therapy targeting NY-ESO-1 tumors using a genetically modified, high-affinity ... and safety results of a pilot study of lete-cel in patients (pts) with advanced or metastatic ... Methods: This is an open label, study of lete-cel in pts with advanced or metastatic MRCLS ... reported. Conclusions: Treatment with a single dose of lete-cel showed anti-tumor activity, including response and ...
Tópico(s): Immunotherapy and Immune Responses
2022 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
FROM OUR CRICKET CORRESPONDENT, FROM OUR SPECIAL CORRESPONDENT, From Our Racing Correspondent, FROM OUR RACING CORRESPONDENT, FROM OUR NORTHERN CORRESPONDENT, FROM OUR NEWMARKET CORRESPONDENT, From Our Rugby Football Correspondent, FROM A STAFF REPORTER, FROM OUR RACKETS CORRESPONDENT, From Our Association Football Correspondent, From a Staff Reporter, FROM OUR CORRESPONDENT, FROM OUR GLIDING CORRESPONDENT, From Our Special Correspondent, FROM OUR NAVAL CORRESPONDENT, FROM OUR OWN CORRESPONDENT, FROM OUR CHESS CORRESPONDENT, From Our Correspondent, From Our Own Correspondent, FROM OUR WEATHER CORRESPONDENT, S. JOHN BERRY, A. TINDAL HART, E. D. CARTWRIGHT, J. G. SMYTH., J. H. HALLETT., WILLIAM SUTTILL, STRETTON LICHFIELD, G. A. K. MISSEN, HENRY CLARK, S. E. ALLCHURCH, W. JARDINE KERR, FROM OUR MUSEUMS CORRESPONDENT, FROM A CORRESPONDENT, Colonel R. F. A. Butterworth, G. W. L., Sir Harold Gillies, Lord Attlee, J. G. L., J. C. V. W., Mr. A. K. Boyd, Miss Pamela Hansford Johnson, Our Agricultural Correspondent, From Our Agricultural Correspondent, From A Correspondent,
... Tadcaster, Father A. Galvin To Be Bishop Of Lete, New Trial Of Strength In South Africa Pass ...
1960 - Gale Group | TDA
Sandra P. D’Angelo, Mihaela Druta, Brian Andrew Van Tine, David A. Liebner, Scott M. Schuetze, Aisha Hasan, Andrew Holmes, Anne Huff, Gurpreet S. Kapoor, Stefan Zajic, Neeta Somaiah,
... treatment are low (1L, <20%; 2L, <10%) [2]. Lete-cel, an autologous T-cell therapy, targets NY- ... MRCLS. Methods: This open label, pilot study evaluates lete-cel efficacy and safety in advanced MRCLS following ... chronic/intercurrent illness restrictions. Stages include screening, leukapheresis, lete-cel manufacture, LD, lete-cel infusion (1– 8 × 10 9 transduced T ... v1.1. In C1 (n=10 patients [pts]), lete-cel was well tolerated and linked with 2 ... aplastic anemia were not reported. Conclusions: A single lete-cel infusion after high LD showed antitumor activity ...
Tópico(s): Immunotherapy and Immune Responses
2021 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Brian K. Hammer, Eiko S. Tateda, Michele S. Swanson,
... flagellar sigma factor FliA; and a new locus, letE. Unlike wild type, post-exponential-phase letA and ... motile, cytotoxic and to infect macrophages efficiently and letE to express sodium sensitivity and maximal motility and ... contrast, intracellular replication was independent of letA, letS, letE or fliA. Together, the data indicate that, as ... cascade mediated by LetA/ LetS, RpoS, FliA and letE that coordinates differentiation of replicating L. pneumophila to ...
Tópico(s): Bacterial biofilms and quorum sensing
2002 - Wiley | Molecular Microbiology
Paola Brancaccio, Francesco Limongelli, Iride Paolillo, Antonio D’Aponte, Vincenzo Donnarumma, Luca Rastrelli,
... gravity, of a bicarbonate calcic mineral water (Acqua Lete®) compared to a minimally mineralized water.88 amateur ... 44) or 1.5 L/day of Acqua Lete® (Group B, n = 44). Measure of body temperature, ... In conclusion all the athletes hydrated with Acqua Lete® showed a positive impact on hydration status after ...
Tópico(s): Sports Performance and Training
2012 - Springer Science+Business Media | Journal of the International Society of Sports Nutrition
Produção Nacional
Revisado por pares
Luciano Pasqualoto Canellas, Gustavo Alves Santos, Anselmo Alpande Moraes, Víctor Marcos Rumjanek, Fábio Lopes Olivares,
... lodo de estação de tratamento de esgoto (AH-LETE), ambos produzidos na cidade do Rio de Janeiro, ... UV-Vis, indicando sistemas mais substituídos nos AH-LETE. A espectroscopia na região do infravermelho (IV) mostrou ... quantitativas nos diferentes tipos de carbono. Os AH-LETE apresentaram maior quantidade de grupos aromáticos e de ...
Tópico(s): Fluoride Effects and Removal
2000 - Sociedade Brasileira de Ciência do Solo | Revista Brasileira de Ciência do Solo
Krishna Balla Mohan, Raj Tiwari Krishna, Gandhiv Kafle, Gautam Shrikrishna, T V Shiva Shankar, Basnet Bandana,
... on forest dependency for maintaining farm fertility in Lete and Kunjo, Mustang (high mountain) and Tibrekot, Kaski ( ... solicit socio-economic and resource use information. In Lete, each HH collected 582 kg Pinus wallichiana needles, ...
Tópico(s): South Asian Studies and Conflicts
2014 - Academic Journals | International Journal of Biodiversity and Conservation
Lindy Charlery, Martin Reinhardt Nielsen, Henrik Meilby, Carsten Smith‐Hall,
... collected in 2006 from two similar Himalayan villages, Lete and Lulang, and again in 2012 after a new road was constructed in 2008 in Lete. Forest strata data were collected in Lete through permanent sample plots (n = 59) measured in ...
Tópico(s): Economic and Environmental Valuation
2016 - Multidisciplinary Digital Publishing Institute | Sustainability
T. Mamie Lih, Wai-Kok Choong, Yu‐Ju Chen, Ting‐Yi Sung,
... proteomics. Therefore, we propose an analysis pipeline called LeTE-fusion (Le, peptide length; T, theoretical values; E, ... difficulty in detecting genome-annotated events. By applying LeTE-fusion on different MS-based proteome data sets, ... proteases. We then further extended the usage of LeTE-fusion on four variant-containing-sequence data sets ( ... be detectable in real shotgun proteomic experiments when LeTE-fusion utilizes the experimentally observed variant-site-containing ... in shotgun proteomics to demonstrate the efficacy of LeTE-fusion on estimating expected observable coverage of variants. ...
Tópico(s): Genomics and Phylogenetic Studies
2018 - American Chemical Society | Journal of Proteome Research
William H. Pearce, Christopher K. Zarins, J. Michael Bacharach,
... Linares K, Aranjuelo N, Kabongo L, Maclair G, Lete N, Ceresa M, García-Familiar A, Macía I ... 1-May-2018. López-Linares K, Kabongo L, Lete N, Maclair G, Ceresa M, García-Familiar A, ...
Tópico(s): Vascular Procedures and Complications
2008 - Lippincott Williams & Wilkins | Circulation
H. Pöllmann, D. EXTERNEST, Arnold Ganser, Barbara Eifrig, W. Kreuz, H. Lenk, Ingrid Pabinger, W. Schramm, Tino F. Schwarz, R. Zimmermann, Nicholas Zavazava, Johannes Oldenburg, Robert Klamroth,
... 41 cases of 'less than expected therapeutic effect' (LETE). Of these, 39 LETE cases were reported in one centre; however, patients ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2007 - Wiley | Haemophilia
Bishnu Hari Wagle, Ram P. Sharma,
... models with Blue pine (Pinus wallichiana) data from Lete and Kunjo areas of Mustang district in Nepal. ... an individual tree level for Blue pine across Lete and Kunjo areas of Mustang district.
Tópico(s): Tree Root and Stability Studies
2012 - Taylor & Francis | Forest Science and Technology
Michael A. Bachman, Michele S. Swanson,
... FliA and the positive activators LetA/S and LetE promote differentiation to the transmissible form. Here we ... multiple copies, rpoS decreases the amounts of csrA, letE, fliA, and flaA transcripts and inhibits the transmission ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2004 - American Society for Microbiology | Infection and Immunity
László Nemes, Víctor Jiménez‐Yuste, L. Rusen, Ana Rosa Cid, Robert J Charnigo, James A. Baumann, Lynne M. Smith, Joan Korth‐Bradley, Pablo Rendo, Rafael López‐López,
... bleeding rate (ABR), less-than-expected therapeutic effect (LETE), and FVIII recovery. Patients were assigned to one ... 5 % of bleeding episodes resolved after one infusion. LETE incidence was 0.06 % and 0.19 % in ...
Tópico(s): Cancer-related gene regulation
2015 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Alberto Gómez Portilla, Victor Echenagusía, Iñaki Cendoya, Aintzane Maqueda,
... systematic review of parasitic leiomyomas recently published by Lete et al. [ [1] Lete I. González J. Ugarte L. Barbadillo N. Lapuente ...
Tópico(s): Uterine Myomas and Treatments
2016 - Elsevier BV | European Journal of Obstetrics & Gynecology and Reproductive Biology
Kaan Kavaklı, Lynne M. Smith, Kazimierz Kuliczkowski, Joan Korth‐Bradley, Chur Woo You, Joanne Fuiman, Silva Zupančić‐Šalek, F. Abdul Karim, Pablo Rendo,
... the incidence of less‐than‐expected therapeutic effect ( LETE ). FIX :C was measured on day 1 and ... responded to the first infusion. No incident of LETE occurred. No thrombotic events or FIX inhibitors were ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2016 - Wiley | Haemophilia
Produção Nacional
Revisado por pares
Luciano Pasqualoto Canellas, Gabriel de Araújo Santos Nelson, Moura Brasil do Amaral Sobrinho, Anselmo Alpande Moraes, Victor Marcos Rumjamek,
... lodo da estação de tratamento de esgoto (AH-LETE) foi estudada através de isotermas de adsorção a ... 55,5g de Cu2+kg-1 de AH-LETE e de 45,9g de Cu2+kg-1 ...
Tópico(s): Adsorption and biosorption for pollutant removal
1999 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Achyut Tiwari, Ze‐Xin Fan, Alistair S. Jump, Zhe‐Kun Zhou,
... growth responses of Himalayan birch, at moist treeline (Lete Lekh) and semi-arid timberline (Chimang Lekh) sites ... between nearby sites such that the wet site (Lete) is getting warmer and wetter, and the dry ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2017 - Springer Science+Business Media | Plant Ecology
Produção Nacional
Revisado por pares
Daniel Flórez-Orrego, Izabela Batista Henriques, Tuong-Van Nguyen, Júlio Augusto Mendes da Silva, Carlos Eduardo Keutenedjian Mady, Luiz Felipe Pellegrini, Ricardo Gandolfi, Héctor Velásquez, Juan Carlos Burbano, Ralf Lattouf, Silvio de Oliveira,
... of the Laboratory of Environmental and Thermal Engineering (LETE) of the Polytechnic School of the University of ... the development of the various research lines at LETE for the past fifteen years. Complex thermodynamic systems, ...
Tópico(s): Phase Equilibria and Thermodynamics
2018 - Elsevier BV | Energy
Carmen Marino, Imma Pagano, Giuseppe Castaldo, Manuela Grimaldi, Maria D’Elia, Angelo Santoro, Aurelio Conte, Paola Molettieri, Chiara Parisella, Michela Buonocore, Anna Maria D’Ursi, Luca Rastrelli,
... consumption of bicarbonate–calcium mineral water marketed under ®Lete. Remarkably, this water, in addition to being rich ... system-wide metabolic effects. Our data show that Lete water is a valid supplement for compensating for ...
Tópico(s): Diet and metabolism studies
2023 - Multidisciplinary Digital Publishing Institute | Metabolites