Produção Nacional
Revisado por pares
Amy C. Bennett, Thaiane R. Sousa, Abel Monteagudo‐Mendoza, Adriane Esquivel‐Muelbert, Paulo S. Morandi, Fernanda Coelho de Souza, Wendeson Castro, Luisa Fernanda Duque, Gerardo Flores Llampazo, Rubens Manoel dos Santos, Eliana Ramos, Emilio Vilanova, Esteban Álvarez‐Dávila, Timothy R. Baker, Flávia R. C. Costa, Simon L. Lewis, Beatriz Schwantes Marimon, Juliana Schietti, Benoît Burban, Érika Berenguer, Alejandro Araujo‐Murakami, Zorayda Restrepo Correa, Wilmar Lopez, Flávia Delgado Santana, Laura Jessica Viscarra, Fernando Elias, Rodolfo Vásquez, Ben Hur Marimon, David Galbraith, Martin J. P. Sullivan, Thaíse Emilio, Nayane Cristina Candida dos Santos Prestes, Jos Barlow, Nathalle Cristine Alencar Fagundes, Edmar Almeida de Oliveira, Patricia Álvarez-Loayza, Luciana F. Alves, Simone Aparecida Vieira, Vinícius Andrade Maia, Luiz E. O. C. Aragão, E.J.M.M. Arets, Luzmila Arroyo, Olaf Bánki, Christopher Baraloto, Plínio Barbosa de Camargo, Jorcely Barroso, Wilder Bento da Silva, Damien Bonal, Alisson Borges Miranda Santos, Roel Brienen, Foster Brown, Carolina V. Castilho, Sabina Cerruto Ribeiro, Víctor Chama Moscoso, Ezequiel Chavez, James A. Comiskey, Fernando Cornejo Valverde, Nállarett Dávila Cardozo, Natália de Aguiar‐Campos, Lia de Oliveira Melo, Jhon del Águila Pasquel, Géraldine Derroire, Mathias Disney, Maria do Socorro, Aurélie Dourdain, Ted R. Feldpausch, Joice Ferreira, Valéria Forni Martins, Toby Gardner, Emanuel Gloor, Gloria Gutierrez Sibauty, René Guillén, Eduardo Hase, Bruno Hérault, Eurídice N. Honorio Coronado, Walter Huaraca Huasco, John P. Janovec, E. Jiménez, Carlos Alfredo Joly, Michelle Kalamandeen, Timothy J. Killeen, Camila Laís Farrapo, Aurora Levesley, Leon Lizon Romano, Gabriela López‐González, Flavio Antônio Maës dos Santos, William E. Magnusson, Yadvinder Malhi, Simone Matias Reis, Karina Melgaço, Omar Aurelio Melo Cruz, Irina Polo, T. Moreno Montanez, Jean Daniel Morel, Mario Percy Núñez Vargas, Raimunda Oliveira de Araújo, Nadir Pallqui Camacho, Alexander Parada Gutierrez, R. Toby Pennington, Georgia Pickavance, John Pipoly, Nigel C. A. Pitman, Carlos Alberto Quesada, Freddy Ramírez Arévalo, Hirma Ramírez‐Angulo, Rafael Flora Ramos, James Richardson, Cléber Rodrigo de Souza, Anand Roopsind, Gustavo Schwartz, Richarlly da Costa Silva, Javier E. Silva‐Espejo, Marcos Silveira, James Singh, Yhan Soto Shareva, Marc Steininger, Juliana Stropp, Joey Talbot, Hans ter Steege, John Terborgh, Raquel Thomas, Luis Valenzuela Gamarra, Geertje van der Heijden, Peter van der Hout, Roderick Zagt, Oliver L. Phillips,
Abstract The tropical forest carbon sink is known to be drought sensitive, but it is unclear which forests are the most vulnerable to extreme events. Forests with hotter and drier baseline conditions may be protected by prior adaptation, or more vulnerable because they operate closer to physiological limits. Here we report that forests in drier South American climates experienced the greatest impacts of the 2015–2016 El Niño, indicating greater vulnerability to extreme temperatures and drought. ...
Tópico(s): Tree-ring climate responses
2023 - Nature Portfolio | Nature Climate Change
Renato Oliveira, Manuel Correia, João Pedro Marto, Mariana Carvalho Dias, Ghada Mohamed, Thanh N. Nguyen, Raul G. Nogueira, Hassan Aboul Nour, Horia Marin, Alex Chebl, Mahmoud Mohammaden, Alhamza R Al‐Bayati, Diogo C Haussen, Mohamad Abdalkader, Johanna T Fifi, Santiago Ortega‐Gutiérrez, Dileep R. Yavagal, Stephan A. Mayer, Georgios Tsivgoulis, Lia Lucas Neto, Diana Aguiar de Sousa,
Endovascular treatment (EVT) is the standard of care for selected patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO).To systematically review the available data on: (1) incidence, predictors, and outcomes of patients with reocclusion after successful EVT for AIS and, (2) the characteristics, complications, and outcomes of patients with reocclusion treated with repeated EVT (rEVT) within 30 days of the first procedure.PubMed was searched (between January 2012 and April 2021) to ...
Tópico(s): Stroke Rehabilitation and Recovery
2022 - BMJ | Journal of NeuroInterventional Surgery
Diana Aguiar de Sousa, Lia Lucas Neto, Patrícia Canhão, José M. Ferro,
Background and Purpose- The role of recanalization of the occluded dural sinus or vein in the outcome of patients with cerebral venous thrombosis (CVT) is not established. We aimed to systematically review, in patients with CVT, (1) the recanalization rate and its association with (2) clinical outcome and (3) CVT recurrence. Methods- Systematic search in MEDLINE (Medical Literature Analysis and Retrieval System Online), Cochrane Library, and clinicaltrials.gov (inception to September 2017). We considered ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2018 - Lippincott Williams & Wilkins | Stroke
Diana Aguiar de Sousa, Lia Lucas Neto, Simon Jung, Sara Penas, Leonidas D Panos, Mirjam R. Heldner, Urs Fischer, Marcel Arnold, Patrícia Canhão, Marwan El‐Koussy, José M. Ferro, Arsany Hakim,
Background and Purpose— The brush sign (BS) is an abnormally accentuated signal drop of the subependymal and deep medullary veins in paramagnetic-sensitive magnetic resonance sequences, previously described in acute ischemic stroke. We aimed to describe the BS in patients with thrombosis of the cerebral veins and sinuses and explore its association with clinical severity, thrombosis extent, parenchymal brain lesion, and clinical prognosis. Methods— We assessed consecutive adult patients admitted ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2019 - Lippincott Williams & Wilkins | Stroke
Diana Aguiar de Sousa, Lia Lucas Neto, Antonio Araúz, Ana Luísa Sousa, Denis Gabriel, Manuel Correia, Raquel Gil‐Gouveia, Sara Penas, Mariana Carvalho Dias, Manuel Correia, Marta Carvalho, Patrícia Canhão, José M. Ferro,
Background and Purpose— The hypothesis that venous recanalization prevents progression of venous infarction is not established in patients with cerebral venous thrombosis (CVT). Evidence is also scarce on the association between residual symptoms, particularly headache, and the recanalization grade. We aimed to assess, in patients with CVT treated with standard anticoagulation, (1) the rate of early venous recanalization, (2) whether lack of early recanalization was predictor of parenchymal brain lesion ...
Tópico(s): Acute Ischemic Stroke Management
2020 - Lippincott Williams & Wilkins | Stroke
David Berhanu, Joana Cardoso Ferreira, Luís Abegão Pinto, Diana Aguiar de Sousa, Lia Lucas Neto, Joana Ferreira,
ObjectivesTo review the optimal diagnostic cut-off of ultrasonographic optic nerve sheath diameter (ONSD) in the diagnosis of increased intracranial pressure (IICP).MethodsA systematic search was conducted of available studies assessing the use of ONSD ultrasonography in patients with suspected IICP. Meta-analysis of diagnostic accuracy of ultrasonographic ONSD was performed using a bivariate model of random effects to summarize pooled sensitivity and specificity. A summary receiver operating characteristics ( ...
Tópico(s): Pituitary Gland Disorders and Treatments
2023 - Elsevier BV | Journal of the Neurological Sciences
José M. Ferro, Martin Bendszus, Olav Jansen, Jonathan M. Coutinho, Francesco Dentali, Adam Kobayashi, Diana Aguiar de Sousa, Lia Lucas Neto, Corinna Miede, Jorge Caria, Holger Huisman, Hans‐Christoph Diener,
Background The effect of different anticoagulants on recanalization after cerebral venous thrombosis has not been studied in a randomized controlled trial. Methods RE-SPECT CVT (ClinicalTrials.gov number: NCT02913326) was a Phase III, prospective, randomized, parallel-group, open-label, multicenter, exploratory trial with blinded endpoint adjudication. Acute cerebral venous thrombosis patients were allocated to dabigatran 150 mg twice daily, or dose-adjusted warfarin, for 24 weeks, after 5–15 days’ ...
Tópico(s): Venous Thromboembolism Diagnosis and Management
2021 - SAGE Publishing | International Journal of Stroke
Produção Nacional
Marília De Sousa Leite, Lia Cardoso de Aguiar,
Objetivo: conhecer os diagnósticos de enfermagem dos pacientes submetidos à colostomia. Metodologia: trata-se de uma pesquisa descritiva, com abordagem quantitativa, realizada nos meses de julho e agosto de 2015. A amostra foi constituída de 15 pacientes colostomizados de um hospital de referência oncológica do estado do Maranhão. Resultados: os diagnósticos de NANDA identificados e mais citados foram padrão de sono prejudicado, baixa autoestima situacional, negação ineficaz, motilidade gastrointestinal ...
Tópico(s): Women's cancer prevention and management
2017 - | Enfermagem em Foco
Produção Nacional
Revisado por pares
Mariana Nicodemo, Lia Renó das Neves, Josafá Carvalho Aguiar, Flaviane de Souza Brito, Isabelle Ferreira, Luciana Barros Sant’Anna, Leandro Raniero, Rodrigo Álvaro Brandão Lopes‐Martins, Paulo Roxo Barja, Emília Ângela Lo Schiavo Arisawa,
To evaluate the effect of human amniotic membrane (hAM) fragment on inflammatory response, proliferation of fibroblast and organization of collagen fibers in injured tendon.Sixty rats were divided into 3 groups: C - surgical procedures without tendon lesion and with simulation of hAM application; I - surgical procedures, tendon injury and simulation of hAM application; T - surgical procedures, tendon injury and hAM application. These groups were subdivided into four experimental times (3, 7, 14 and 28 days). ...
Tópico(s): Periodontal Regeneration and Treatments
2017 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Produção Nacional
Revisado por pares
Rogério Santos‐Silva, Sérgio Tufik, Silvia G. Conway, José Augusto de Aguiar Carrazedo Taddei, Lia Bittencourt,
To present the rational design, sampling, and procedures utilized in an Epidemiologic Sleep Study carried out in 2007 to establish the epidemiologic profile of sleep disorders in the adult population of a large metropolitan city, Sao Paulo, Brazil.A population-based survey adopting a probabilistic three-stage cluster sample of Sao Paulo was used to represent the population according to gender, age (20-80 years), and socioeconomic class. Questionnaires, actigraphy, polysomnography (PSG), and blood ...
Tópico(s): Sleep and Wakefulness Research
2009 - Elsevier BV | Sleep Medicine
Produção Nacional
Revisado por pares
Renan Magalhães Montenegro, Aline Dantas Costa‐Riquetto, Virgínia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Lucas Santos de Santana, Alexander A.L. Jorge, Lia Beatriz de Azevedo Souza Karbage, Lindenberg Barbosa Aguiar, Francisco Herlânio Costa Carvalho, Milena Gurgel Teles, Catarina Brasil d’Alva,
Background. Dunnigan-type familial partial lipodystrophy, a rare autosomal dominant disease caused by heterozygous missense mutations in LMNA gene presents regional loss of subcutaneous adipose tissue from puberty. But the same mutation may present huge clinical heterogeneity. Methods. We report 4 patients from the same family with p.R582C LMNA mutation, 3 of them with homozygous and 1 with heterozygous state, presenting 3 distinct lipodystrophic phenotypes and we compare their clinical and metabolic ...
Tópico(s): RNA regulation and disease
2018 - Frontiers Media | Frontiers in Endocrinology
Produção Nacional
Revisado por pares
Tânia Maria de Araújo, Estela M. L. Aquino, Greice Maria de Souza Menezes, Cristiane Oliveira Santos, Lia Aguiar,
OBJETIVO: Avaliar a associação entre demanda psicológica e controle sobre o trabalho e a ocorrência de distúrbios psíquicos menores entre trabalhadoras de enfermagem. MÉTODOS: Estudo de corte transversal, incluindo 502 trabalhadoras de enfermagem de um hospital público de Salvador, Bahia. O Modelo Demanda-Controle, de Karasek, foi utilizado para avaliar as dimensões psicossociais estudadas. Para mensuração de distúrbios psíquicos menores (DPM), utilizou-se o SRQ-20. RESULTADOS: A prevalência de DPM ...
Tópico(s): Health, Nursing, Elderly Care
2003 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Pedro Nazareth Aguiar, Ramon Andrade de Mello, Carme lia Maria Noia Barreto, Luke A. Perry, Jahan C. Penny‐Dimri, Hakaru Tadokoro, Gilbertode Lima Lopes,
Lung cancer is the leading cause of cancer-related deaths in the world. Immune checkpoint inhibitors (ICI) stimulate cytotoxic lymphocyte activity against tumour cells. These agents are available for the treatment of non-small cell lung cancer (NSCLC) after failure of platinum-based therapy. One recent study has demonstrated that ICI monotherapy was superior to platinum-based chemotherapy for first-line treatment. Nevertheless, this benefit was only for a minority of the population (30%) whose tumour ...
Tópico(s): Lung Cancer Research Studies
2017 - Elsevier BV | ESMO Open
Neusa Figueiredo, Sara Raquel Mota Merelo de Aguiar, Pedro L. Falé, Lia Ascensão, Maria Luísa Serralheiro, A.R. Lino,
Aqueous extracts of Plectranthus barbatus and Plectranthus ecklonii are traditionally used as anti-inflammatory and anti-fungal agents. The effect of these extracts and of its main component, rosmarinic acid, on the viability of the cariogenic bacteria, Streptococcus sobrinus and Streptococcus mutans, was determined by MIC and MBC. The influence of these extracts on the biofilm formation as well as on the inhibition of glucosyltransferase enzyme, produced by these species, was also analysed. Aqueous ...
Tópico(s): Oral microbiology and periodontitis research
2009 - Elsevier BV | Food Chemistry
Produção Nacional
Revisado por pares
Fernanda Montenegro de Carvalho Araújo, Raimunda Sâmia Nogueira Brilhante, Luciano Pamplona de Góes Cavalcanti, Marcos Fábio Gadelha Rocha, Rossana de Aguiar Cordeiro, Anne Carolinne Bezerra Perdigão, I.S. Miralles, Lia Cavalcante de Araújo, R.M.C. Araújo, Elza Gadelha Lima, José Júlio Costa Sidrim,
The involvement of the central nervous system in dengue infections has been reported in countries where the disease in endemic. The purpose of this study was to determine whether an enzyme-linked immunosorbent assay kit designed to detect the dengue NS1 antigen in serum was able to detect this antigen in cerebral spinal fluid (CSF) samples from patients with fatal outcomes. To evaluate the sensitivity of the kit, 26 dengue-positive CSF samples were used. The Pan-E Dengue Early kit was able to detect ...
Tópico(s): Malaria Research and Control
2011 - Elsevier BV | Journal of Virological Methods
Produção Nacional
Revisado por pares
Fábio de Azevedo Caparroz, Milena de Almeida Torres Campanholo, Renato Stefanini, Tatiana de Aguiar Vidigal, Leonardo Haddad, Lia Bittencourt, Sérgio Tufik, Fernanda Louise Martinho Haddad,
Tópico(s): Gastroesophageal reflux and treatments
2019 - Springer Science+Business Media | Sleep And Breathing
Bianca Ott Andrade, William Dröse, Cassiana Alves de Aguiar, Elisa Teixeira Aires, Diego Janisch Alvares, Rosa Lía Barbieri, Cláudio José Barros de Carvalho, Marie Luise Carolina Bartz, Fernando Gertum Becker, Glayson Ariel Bencke, Anelise Beneduzi, Jorge Bernardo Silva, Betina Blochtein, Ilsi Iob Boldrini, Piter Kehoma Boll, Juçara Bordin, Rosa Mara Borges da Silveira, Márcio Borges Martins, Camila Bosenbecker, João Alberto Leão Braccini, Bruna Marmitt Braun, Rosângela Brito, George Gardner Brown, Henrique Mallmann Büneker, Cristiano Roberto Buzatto, Adriano Cavalleri, Sônia Zanini Cechin, Patrick Colombo, Reginaldo Constantino, Cíntia Fernanda da Costa, Marina Schmidt Dalzochio, Marcelo Gehlen de Oliveira, Rafael Antunes Dias, Luana Amaral dos Santos, Adriane da Fonseca Duarte, Juliano Lessa Pinto Duarte, Jaqueline Durigon, Mayara Escobar Da Silva, Priscila Porto Alegre Ferreira, Talita Ferreira, Juliano Ferrer, Viviane Gianluppi Ferro, Carla Suertegaray Fontana, Marcelo Duarte Freire, Thales Renato Ochotorena de Freitas, Daniel Galiano, Marinês Garcia, Tiágo Gomes dos Santos, Lucas Roberto Pereira Gomes, Felipe Gonzatti, Marco Silva Gottschalk, Gustavo Graciolli, Camille Eichelberger Granada, Martin Grings, Pablo Santos Guimarães, Ingrid Heydrich, Samanta Iop, João André Jarenkow, Patrícia Jungbluth, Márcia Isabel Käffer, Lucas Augusto Kaminski, Diego Costa Kenne, Frederico Dutra Kirst, Tiago Kütter Krolow, Rodrigo Ferreira Krüger, Bruno Busnello Kubiak, Ana María Leal-Zanchet, Daniel Loebmann, Dióber Borges Lucas, Elaine Lucas, André Luís Luza, Iberê Farina Machado, Bruno Madalozzo, Renan Maestri, Luiz Roberto Malabarba, Raúl Maneyro, Marco Antonio Tonus Marinho, Roberta Marques, Kimberly S. Marta, Diego Da Silveira Martins, Giovana Da Silva Martins, Thiago Rambo Martins, Anderson Santos de Mello, Ramon Luciano Mello, Milton de Souza Mendonça, Ana Beatriz Barros de Morais, Felipe Ferraz Figueiredo Moreira, Leonardo Felipe Bairos Moreira, Luciano de Azevedo Moura, Michelle Helena Nervo, Ricardo Ott, Patrícia Paludo, Luciane Maria Pereira Passaglia, Eduardo Périco, Erika Sant'Anna Petzhold, Mateus Marques Pires, Jean Lucas Poppe, Fernando Marques Quintela, Mateus Raguse-Quadros, María João Ramos Pereira, Samuel Renner, Felipe Barbosa Ribeiro, José Ricardo Inácio Ribeiro, Everton Nei Lopes Rodrigues, Patrícia Elesbão da Silva Rodrigues, Helena Piccoli Romanowski, Tatiana Petersen Ruschel, Suelen Da Silva Alves Saccol, Marcoandré Savaris, Fernanda Schmidt Silveira, Hermes José Schmitz, Ana Emília Siegloch, Ricardo Russo Siewert, Pedro Joel Silva da Silva Filho, Aline G. Soares, Alexandre Somavilla, Patrícia Sperotto, Márcia Regina Spies, Flávia Pereira Tirelli, Alexandro Marques Tozetti, Laura Verrastro, Cleusa Vogel Ely, Ândrio Zafalon Da Silva, Caroline Zank, Edison Zefa, Gerhard E. Overbeck,
Knowledge on biodiversity is fundamental for conservation strategies. The Brazilian Pampa region, located in subtropical southern Brazil, is neglected in terms of conservation, and knowledge of its biodiversity is fragmented. We aim to answer the question: how many, and which, species occur in the Brazilian Pampa? In a collaborative effort, we built species lists for plants, animals, bacteria, and fungi that occur in the Brazilian Pampa. We included information on distribution patterns, main habitat ...
Tópico(s): Species Distribution and Climate Change
2023 - International Biogeography Society | Frontiers of Biogeography
Produção Nacional
Revisado por pares
Marília Perrelli Valença, Tatiane Almeida de Menezes, Adriano Almeida Calado, Geraldo de Aguiar Cavalcanti,
Tópico(s): Congenital Anomalies and Fetal Surgery
2012 - Springer Nature | Spinal Cord
Produção Nacional
Revisado por pares
Nuno R. Faria, Josh Quick, Ingra Morales Claro, Julien Thézé, Jhennifer Guimarães Lourenço de Jesus, Marta Giovanetti, Moritz U. G. Kraemer, Sarah C. Hill, Allison Black, Antônio Charlys da Costa, L.C. Junqueira Franco, Serena Pocas Moreno Silva, Chieh‐Hsi Wu, Jayna Raghwani, Simon Cauchemez, Louis du Plessis, Mariana Pastorello Verotti, W. K. de Oliveira, Eduardo Hage Carmo, Giovanini Evelim Coelho, A. C. F. S. Santelli, Livia Vinhal, Cláudio Maierovitch Pessanha Henriques, Jared T. Simpson, Matthew Loose, Kristian G. Andersen, Nathan D. Grubaugh, Sneha Somasekar, Charles Y. Chiu, José Esteban Muñoz‐Medina, César González-Bonilla, Carlos F. Arias, Lia Laura Lewis‐Ximenez, Sally A. Baylis, Alexandre Chieppe, Shirlei Ferreira de Aguiar, Carlos Augusto Fernandes, P. S. Lemos, Bruna Laís Sena do Nascimento, H. A. O Monteiro, Isadora Cristina de Siqueira, Maria Gabriela de Queiroz, Themis Rocha de Souza, João Felipe Bezerra, Marisa Lemos, G. F. Pereira, D. Loudal, Lúcia Cristina Corrêa Moura, Rafael Dhália, R. F. França, Tereza Magalhães, Ernesto T. A. Marques, Thomas Jaenisch, Gabriel Luz Wallau, Magliones Carneiro de Lima, Valdinete Alves do Nascimento, Erenilde Marques de Cerqueira, Maricélia Maia de Lima, D. L. Mascarenhas, José Pereira de Moura Neto, Anna S. Levin, Tânia Regina Tozetto‐Mendoza, Sílvia Nunes Szente Fonseca, Maria Cássia Mendes-Corrêa, Flavio Augusto de Pádua Milagres, Aluísio Augusto Cotrim Segurado, Edward C. Holmes, Andrew Rambaut, Trevor Bedford, Márcio Roberto Teixeira Nunes, Éster Cerdeira Sabino, Luíz Carlos Júnior Alcântara, Nicholas J. Loman, Oliver G. Pybus,
Virus genomes reveal the establishment of Zika virus in Brazil and the Americas, and provide an appropriate timeframe for baseline (pre-Zika) microcephaly in different regions. Three papers in this issue present a wealth of new Zika virus (ZIKV) genome sequences and further insights into the genetic epidemiology of ZIKV. Nathan Grubaugh et al. provide 39 new ZIKV genome sequences from infected patients and Aedes aegypti mosquitoes in Florida. Phylogenetic analysis suggests that the virus has been ...
Tópico(s): Viral Infections and Vectors
2017 - Nature Portfolio | Nature
Produção Nacional
Revisado por pares
Rogério Santos‐Silva, Lia Bittencourt, Maria Laura Nogueira Pires, Marco Túlio de Mello, José Augusto de Aguiar Carrazedo Taddei, Ana Amélia Benedito‐Silva, Celine Pompéia, Sérgio Tufik,
The aim of this study was to compare the prevalence of sleep habits and complaints and to estimate the secular trends through three population-based surveys carried out in 1987, 1995, and 2007 in the general adult population of the city of Sao Paulo, Brazil.Surveys were performed using the same three-stage cluster-sampling technique in three consecutive decades to obtain representative samples of the inhabitants of Sao Paulo with respect to gender, age (20-80 years), and socio-economic status. Sample ...
Tópico(s): Sleep and Wakefulness Research
2010 - Elsevier BV | Sleep Medicine
Produção Nacional
Revisado por pares
Nadine Glesse, Priscila Vianna, Lia Mara Gomes Paim, Maria Cristina Cotta Matte, Ana Karine Kramer de Aguiar, P L Palhano, Odirlei André Monticielo, Claiton Viegas Brenol, Ricardo Machado Xavier, José Artur Bogo Chies,
Background Systemic lupus erythematosus (SLE) is an autoimmune disease marked by the disruption of the immune homeostasis. Patients exhibit a wide range of clinical manifestations, and environmental and genetic factors are involved in SLE pathogenesis. Evidence suggests that abnormalities in the cellular and molecular events that coordinate apoptosis may favour the generation of autoantigens involved in autoimmunity. In this way, the apoptotic deregulation may be affected by polymorphic variants ...
Tópico(s): Cell death mechanisms and regulation
2016 - SAGE Publishing | Lupus
Diana Aguiar de Sousa, Maria Conceição Pereira Santos, Ana Serra‐Caetano, Lia Lucas Neto, Ana Luísa Sousa, Denis Gabriel, Manuel Correia, Raquel Gil‐Gouveia, Renato Oliveira, Sara Penas, Mariana Carvalho Dias, Manuel Correia, Marta Carvalho, Ana E. Sousa, Patrícia Canhão, José M. Ferro,
Experimental studies suggest inflammation can contribute to blood barrier disruption and brain injury in cerebral venous thrombosis (CVT). We aimed to determine whether blood biomarkers of inflammation were associated with the evolution of brain lesions, persistent venous occlusion or functional outcome in patients with CVT.Pathophysiology of Venous Infarction-Prediction of Infarction and Recanalization in CVT (PRIORITy-CVT) was a multicenter prospective cohort study of patients with newly diagnosed ...
Tópico(s): Acute Ischemic Stroke Management
2020 - Wiley | European Journal of Neurology
Produção Nacional
Denise Tomaz Aguiar, Lia Carneiro Silveira, Sandra Mara Nunes Dourado,
A vivência da maternidade é abordada no modelo médico científico do ponto de vista orgânico. Porém, para algumas mulheres, isso se dá como uma experiência de intenso sofrimento psíquico. Desenvolvemos uma reflexão teórica visando refletir acerca das possibilidades de abordagem dessa questão na perspectiva de uma clínica do sujeito, conforme delimitado na abordagem psicanalítica, contrapondo-a à visão do modelo médico científico. A ciência moderna institui-se como práxis pela exclusão do sujeito, ...
Tópico(s): Psychotherapy Techniques and Applications
2011 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Escola Anna Nery
Diana Aguiar de Sousa, Maria Conceição Pereira Santos, Ana Serra‐Caetano, Lia Lucas Neto, Ana Luísa Sousa, Denis Gabriel, Manuel Correia, Raquel Gil‐Gouveia, Renato Oliveira, Sara Penas, Mariana Carvalho Dias, Manuel Correia, Marta Carvalho, Ana E. Sousa, Patrícia Canhão, José M. Ferro,
Abstract Background Elucidating mechanisms of brain damage in cerebral venous thrombosis (CVT) would be instrumental to develop targeted therapies and improve prognosis prediction. Matrix metalloproteinase-9 (MMP-9), a gelatinase that degrades major components of the basal lamina, has been associated to blood–brain barrier disruption. We aimed to assess, in patients with CVT, the temporal change in serum concentrations of MMP-9 and its association with key imaging and clinical outcomes. Methods Pathophysiology ...
Tópico(s): Acute Ischemic Stroke Management
2021 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Produção Nacional
Revisado por pares
Vinicius M. Mello, Bárbara V. Lago, Paulo Sérgio Fonseca de Sousa, Francisco Campello do Amaral Mello, Caroline B. Souza, Laura Cristina Machado Pinto, Cleber F. Ginuino, Carlos A. S. Fernandes, Shirlei Ferreira de Aguiar, Lívia Melo Villar, Elisabeth Lampe, Juliana Gil Melgaço, Lia Laura Lewis‐Ximenez,
Hepatitis A virus (HAV) outbreaks among men who have sex with men (MSM) have been reported worldwide and associated primarily with sexual transmission through oral-anal sex. Here, we provide the molecular and evolutionary description of a European strain, linked to HAV outbreaks among MSM, detected in a Brazilian homosexual couple. Bayesian analysis provided evidence that the viral isolates were introduced in Brazil from Spain between the end of 2016 and the beginning of 2017.
Tópico(s): Viral gastroenteritis research and epidemiology
2019 - Multidisciplinary Digital Publishing Institute | Viruses
Diana Aguiar de Sousa, Lia Lucas Neto,
... Cerebral Venous Thrombosis Diana Aguiar de Sousa and Lia Lucas Neto Diana Aguiar de SousaDiana Aguiar de Sousa Correspondence to: Diana Aguiar ...
Tópico(s): Intracerebral and Subarachnoid Hemorrhage Research
2024 - Lippincott Williams & Wilkins | Stroke
Produção Nacional
Revisado por pares
G. de C. Moraes, Luis Paulo Baldisera Schorr, Jéssica Thalheimer de Aguiar, Tarik Cuchi, Lia de Oliveira Melo,
The knowledge of the ecological characteristics of forest species has helped to identify the patterns of plant formations and their management for use.This study aimed to know the diametric structure and the spatial arrangement of the Manilkara elata species submitted to a sustainable management plan in the Tapajós National Forest located in Belterra-Pará.A total of 79 permanent plots with dimensions of 50 m x 50 m (0.25 ha) were used, resulting in a total of 19.75 ha sampled.All individuals of the ...
Tópico(s): Agricultural and Food Sciences
2017 - Centro Científico Knowing | Enciclopédia Biosfera
Ana Amélia Amorim Carvalho, Cristina Almeida Aguiar, Henrique Santos, Lía Raquel Oliveira, María Aldina Marques, Romana Maciel,
This paper reports the use of podcasts in blended-learning at the University of Minho, in Portugal. Six lecturers created their own podcasts with different purposes in order to support their undergraduate and graduate courses and their students' (n=318) learning. The reported study belongs to a broader project about the impact of podcasts in blended-learning and it reports data from two semesters. Results give evidence of students' acceptance regarding podcasts although they do not yet make use of ...
Tópico(s): Social Media in Health Education
2009 - Springer Science+Business Media | IFIP advances in information and communication technology
Produção Nacional
Silva Lemos Ala iacute de, Leopoldino Coelho Rodrigues Vanessa, Vin iacute cius Oliveira Barros Marcus, Muhammad Torequl Islam, Pablo Sousa de Aguiar Ra iacute, Maria Oliveira Ferreira da Mata Ana, Melo de Carvalho Ricardo, Fernanda Correia Jardim Paz M aacute rcia, Mendes Feitosa Chistiane, eacute lia de Carvalho Melo Ana, Pablo Sousa de Aguiar Ra iacute, eacute lia Carvalho Melo Cavalcante Ana, Pablo Sousa de Aguiar Ra iacute, Maria Oliveira Ferreira da Mata Ana, Fernanda Correia Jardim Paz M aacute rcia, Leopoldino Coelho Rodrigues Vanessa, Muhammad Torequl Islam, Maria Oliveira Ferreira da Mata Ana, Fernanda Correia Jardim Paz M aacute rcia, Mendes Feitosa Chistiane, eacute Carvalho Melo Cavalcante Ana, Muhammad Torequl Islam, Pablo Sousa de Aguiar Ra iacute, Maria Oliveira Ferreira da Mata Ana, Melo de Carvalho Ricardo, Mendes Feitosa Chistiane,
Isotretinoin (ITN), chemically known as 13-cis-retinoic acid, is a part of the broad group of compounds related to vitamin A. It is particularly employed in the treatment of nodular cystic acne and as an inhibitor of proliferation of neoplastic cells, by exerting a regulatory effect on the cell differentiation. This study aimed at investigating the possible oxidative effects of ITN and modulatory effects of vitamins A and C in mutant and non-mutant Saccharomyces cerevisiae strains. In addition, to ...
Tópico(s): Biocrusts and Microbial Ecology
2016 - Academic Journals | AFRICAN JOURNAL OF BIOTECHNOLOGY
Produção Nacional
Revisado por pares
Tatiana de Aguiar Vidigal, Fernanda Louise Martinho Haddad, Luiz Carlos Gregório, Dalva Poyares, Sérgio Tufik, Lia Bittencourt,
Tópico(s): Asthma and respiratory diseases
2012 - Springer Science+Business Media | Sleep And Breathing